The nerve agent sarin causes a deadly overstimulation of the nervous system that can be stopped if treated with an antidote within minutes of poisoning. Today, a ground-breaking study has been published in PNAS, which in detail describes how such a drug works. Researchers at the Swedish Defence Research Agency, Umeå University and in Germany are behind the study.
Twenty years ago, there were only two species of mouse lemurs. Today, including the newly-discovered species, mouse lemurs comprise 24 species. According to the International Union for Conservation of Nature's Red List, 94 percent of lemurs are threatened with extinction.
Stressing a worm's mitochondria at a key time in early development is known to improve their metabolic health and extend lifespan. UC Berkeley researchers discovered what's behind this: enzymes that tag DNA and make epigenetic changes that affect the expression of mitochondrial genes long into adulthood, making the mitochondria more efficient. In long-lived mice, these same enzymes are up-regulated, implying that they play a key role in boosting metabolic function in mammals as well.
Reuben Brough is running around a gym at a local youth center waving his hands in the air and screeching like a cheetah. A stream of children is in hot pursuit of him and four other students from the University of Vermont who implore the preschoolers to 'catch the cheetah.' It looks like total chaos, but there's a method to the madness, which is really a highly structured, research-based fitness program called Children and Teachers (CATs) on the Move.
Researchers from Brazil and the US mapped and characterized an extensive reef system in an unlikely area of the Brazilian coast. Oil and gas companies operate close to the reefs.
Research has shown the significance of social relationships in influencing adult human behavior and health; however, little is known about how children's perception of their social networks correlates with stress and how it may influence development. Now, a University of Missouri research team has determined that children and adolescents physically react to their social networks and the stress those networks may cause.
A compilation of recommendations from a 2015 workshop organized by the PETA International Science Consortium Ltd. appears in a report in Archives of Toxicology.
New research from Wake Forest University studies the role testosterone plays in the evolutionary process of foot-flag signals used by Bornean rock frogs during mating season.
Research in a mouse model led by Andreas Bäumler, professor of medical immunology and microbiology at UC Davis Health System, has identified the chain of events that occur within the gut lumen after antibiotic treatment that allow 'bad' bugs to flourish.
Before the therapeutic potential of using human tissue-derived mesenchymal stromal cells (MSC) to treat immune and degenerative diseases can be fully determined, the effects of freeze-thawing and intravenous delivery on MSC function must be understood. A new study reporting the changes in MSC gene expression associated with cryopreservation and exposure to the mouse lung is published in Stem Cells and Development.