How do the cells in a human embryo know where they are located in the body and how they should develop? Why do certain cells form a finger while others do not? Freiburg biologists have explained the mechanisms that control these steps by showing why veins form at particular points in the wing of a fruit fly. The protein Pentagone spreads a particular signal in the wing that tells the cells how to behave.
Oxford University Press and the Entomological Society of America have released a special collection of free articles on the Asian tiger mosquito (Aedes albopictus).
Researchers at Tufts University School of Dental Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts, led by Jonathan Garlick, have established for the first time that skin cells from diabetic foot ulcers can be reprogrammed to acquire properties of embryonic-like cells.
For patients treated in a hospital, the risk of death from acute myeloid leukemia was elevated in three regions of North Carolina compared to a benchmark.
The enzyme sirtuin 6, or SIRT6, serves many key biological functions in regulating genome stability, DNA repair, metabolism and longevity, but how its multiple enzyme activities relate to its various functions is poorly understood. A team of Cornell University researchers has devised a method for isolating one specific enzyme activity to determine its contribution and lead to better overall understanding of SIRT6.
A meta-analysis of studies in people with diabetes and pre-diabetes has shown that oral aloe vera use was associated with significant decreases in both fasting blood glucose (FBG) and hemoglobin A1c (HbA1c). The data indicate that people with a FBG >200 mg/dL may benefit the most, according to an article in The Journal of Alternative and Complementary Medicine.
A University of Miami math professor has developed a scientific model to address the various ways the Zika virus proliferates. The study, published June 17 in Scientific Reports, reveals that mosquito control should remain the most important mitigation method to control the virus. However, the study reveals that Zika is a complicated virus and sexual transmission increases the risk of infection and prolongs the outbreak.
A research team led by investigators at Beth Israel Deaconess Medical Center (BIDMC) and Seoul National University has developed a new electric mesh device that can be wrapped around the heart to deliver electrical impulses and thereby improve cardiac function in experimental models of heart failure, a major public health concern and leading cause of mortality and disability.
A small, squishy vehicle equipped with soft wheels rolls over rough terrain and runs under water. Future versions of the versatile vehicle might be suitable for search and rescue missions after disasters, deep space and planet exploration, and manipulating objects during magnetic resonance imaging (MRI), according to its creators at Rutgers University. Their most important innovation is a soft motor that provides torque without bending or extending its housing.
The College of American Pathologists, the International Association for the Study of Lung Cancer, and the Association for Molecular Pathology announced today the open comment period for the revised evidence-based guideline, 'Molecular Testing Guideline for Selection of Lung Cancer Patients for EGFR and ALK Tyrosine Kinase Inhibitors.'