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Public Release: 3-Feb-2012
 Journal of Allergy and Clinical ImmunologyLower levels of sunlight link to allergy and eczema Increased exposure to sunlight may reduce the risk of both food allergies and eczema in children, according to a new scientific study published this week. Contact: Andrew Gould
Public Release: 27-Jan-2012
British Journal of DermatologyBody location plays part in scratching pleasure New research from Gil Yosipovitch, M.D., Ph.D., professor of dermatology at Wake Forest Baptist Medical Center and a world-renowned itch expert, shows that how good scratching an itch feels is related to the itch's location. 
NIH/National Institute of Arthritis and Musculoskeletal and Skin Disease
Contact: Bonnie Davis
Public Release: 26-Jan-2012
ImmunityGatekeeper signal controls skin inflammation A new study unravels key signals that regulate protective and sometimes pathological inflammation of the skin. The research, published online on Jan. 26th in the journal Immunity by Cell Press, identifies a "gatekeeper" that, when lost, can cause inflammatory skin disease in the absence of injury or infection. The findings may eventually lead to new treatment strategies for the more than 10 percent of people in the western world that suffer from inflammatory skin diseases. Contact: Lisa Lyons
Public Release: 25-Jan-2012
Skin Pharmacology and PhysiologyPycnogenol (French maritime pine bark extract) shown to improve visible signs of aging in new study Natural supplement Pycnogenol, an antioxidant plant extract from the bark of the French maritime pine tree, was found to improve skin hydration and elasticity in women in a clinical trial published this month in Skin Pharmacology and Physiology. The study was conducted at the Leibniz Research Institute for Environmental Medicine in Dusseldorf, Germany and examined 20 healthy women, aged 55-68 years. Participants were given 75 mg of Pycnogenol per day, over a period of 12 weeks. Contact: Katherine Davis
Public Release: 25-Jan-2012
PLoS ONECDC reports that unexplained skin condition is non-infectious, not linked to environmental cause The US Centers for Disease Control and Prevention has completed a comprehensive study of an unexplained skin condition commonly referred to as Morgellons. Contact: Yael Franco
Public Release: 17-Jan-2012
Journal of Clinical InvestigationJCI online early table of contents: Jan. 17, 2012 This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, Jan. 17, 2012, in the JCI: "Plasmacytoid DCs: tumor-killing immune cells"; "How to prevent hepatitis B virus reproducing"; "Modulating the inflammatory environment in liver cancer modifies outcome"; and "Maintaining integrity in the kidney." Contact: Karen Honey
Public Release: 17-Jan-2012
Journal of Clinical InvestigationPlasmacytoid DCs: Tumor-killing immune cells Some skin cancers can be successfully treated with a prescription cream containing the compound imiquimod. One of the more complex aspects of imiquimod's antitumor effects is its ability to modify the immune response. Researchers have now identified a new way in which imiquimod modifies the immune system to clear tumors in a mouse model of melanoma, the most deadly form of skin cancer.
Austrian Science Fund, Austrian Federal Government, European Commission
Contact: Karen Honey
Public Release: 16-Jan-2012
Archives of DermatologyUH Case Medical Center publishes study on novel treatment for skin lymphoma Promising findings on a novel combination treatment approach for a chronic type of skin lymphoma are being published today in JAMA's Archives of Dermatology by clinical researchers from Seidman Cancer Center at University Hospitals Case Medical Center and Case Western Reserve University School of Medicine.
NIH/National Cancer Institute
Contact: Alicia Reale
Public Release: 10-Jan-2012
Breast Cancer Research and TreatmentTreatment of psoriasis gets new hope Researchers at Linkoeping University in Sweden are now launching a plan to effectively treat psoriasis. The study focuses on the psoriasin protein. Contact: Charlotta Enerbäck
Public Release: 9-Jan-2012
Proceedings of the National Academy of SciencesStudy confirms new strategy in fight against infectious diseases New research shows that infectious disease-fighting drugs could be designed to block a pathogen's entry into cells rather than to kill the bug itself. Historically, medications for infectious diseases have been designed to kill the offending pathogen. This new strategy is important, researchers say, because many parasites and bacteria can eventually mutate their way around drugs that target them, resulting in drug resistance.
National Institues of Health
Contact: Abhay Satoskar
Public Release: 5-Jan-2012
MU researcher's photoacoustic device finds cancer cells before they become tumors University of Missouri researchers are one step closer to melanoma cancer detection at the cellular level, long before tumors have a chance to form. Commercial production of a device that measures melanoma using photoacoustics, or laser-induced ultrasound, will soon be available to scientists and academia for cancer studies. The commercial device also will be tested in clinical trials to provide the data required to obtain US Food and Drug Administration approval for early diagnosis of metastatic melanoma and other cancers. Contact: Steven Adams
Public Release: 3-Jan-2012
Journal of Clinical InvestigationResearch identifies how time heals all wounds Wound healing requires interactions between cells resident at the damaged site and infiltrating immune cells. Endothelial progenitor cells (EPCs) come from the bone marrow and are key to the production of new vessels. Here, Toshikazu Kondo and colleagues demonstrate that the chemokine CCL5 helps to direct the recruitment of EPCs to sites of wounding by acting on the chemokine receptor CCR5. These findings identify the CCR5/CCL5 axis as a potential target to promote healing.
Ministry of Education, Culture, Science, and Technology of Japan, Wakayama Medical University
Contact: Karen Honey
Public Release: 22-Dec-2011
CellHow skin is wired for touch Compared to our other senses, scientists don't know much about how our skin is wired for the sensation of touch. Now, research reported in the Dec. 23 issue of the journal Cell, a Cell Press publication, provides the first picture of how specialized neurons feel light touches, like a brush of movement or a vibration, are organized in hairy skin. Contact: Lisa Lyons
Public Release: 19-Dec-2011
First aid after tick bites They come out in the spring, and each year they spread further – the ticks. Thirty percent of them transmit borrelia pathogens, the causative agent of Lyme borreliosis that can damage joints and organs. The disease often goes undetected. In the future, a new type of gel is intended to prevent an infection – if applied after a tick bite. Contact: Dr. Jens Knauer
Public Release: 15-Dec-2011
International Wound JournalResearchers investigate link between autoimmune diseases and wounds that don't heal Millions of Americans suffer from wounds that don't heal, and while most are typically associated with diabetes, new research has identified another possible underlying cause – autoimmune diseases. The finding, published today in the International Wound Journal, represents an unappreciated link that could lead to important new insights in wound healing, say researchers at Georgetown University Medical Center.
Georgetown-Howard Universities Center for Clinical & Translational Science
Contact: Karen Mallet
Public Release: 12-Dec-2011
Journal of Clinical InvestigationJCI online early table of contents: Dec. 12, 2011 This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, Dec. 12, 2011, in the JCI: Predicting resistance to brain tumor chemotherapy; Disease progression halted in rat model of Lou Gehrig's disease; Weaning transplant recipients from their immunosuppressive drugs; Feedback blocked by the regulatory RNA miR-30*; Modeling blood diseases in vitro; Finding a new immune function for NEMO; Putting a stop to immune responses; and others. Contact: Karen Honey
Public Release: 1-Dec-2011
Journal of Investigative DermatologyLower antioxidant level might explain higher skin-cancer rate in males A new study may help explain why men are three times more likely than women to develop a common form of skin cancer. The study found that male mice had lower levels of an important skin antioxidant than female mice and higher levels of certain cancer-linked inflammatory cells. As a result, men may be more susceptible to oxidative stress in the skin, which may raise their risk of skin cancer compared to women.
NIH/National Cancer Institute, Valvano Foundation for Cancer Research
Contact: Darrell E. Ward
Public Release: 30-Nov-2011
Biomedical Optics ExpressScientists use laser imaging to assess safety of zinc oxide nanoparticles in sunscreen Ultra-tiny zinc oxide (ZnO) particles are among the ingredients list of some commercially available sunscreen products, raising concerns about whether the particles may be absorbed beneath the outer layer of skin. To help answer these questions, a team of scientists from Australia and Switzerland have developed a way to optically test the concentration of ZnO nanoparticles at different skin depths. The results were published this month in the OSA's open-access journal Biomedical Optics Express. Contact: Angela Stark
Public Release: 22-Nov-2011
Nature CommunicationsP Rex-1 protein key to melanoma metastasis Researchers from UNC Lineberger Comprehensive Cancer Center are part of a team that has identified a protein, called P-Rex1, that is key to the movement of cells called melanoblasts. When these cells experience uncontrolled growth, melanoma develops.
Association of International Cancer, National Institutes of Health, American Cancer Society, Cancer Research UK, Target-Melanoma
Contact: Ellen de Graffenreid
Public Release: 21-Nov-2011
Archives of Facial Plastic SurgeryLaser removal may be advantageous for treating precancerous skin lesions Carbon dioxide laser ablation may have a role as an alternative treatment for a common precancerous skin lesion known as lentigo maligna when surgery or radiation therapy is not feasible, according to a report in the November/December issue of the Archives of Facial Plastic Surgery, one of the JAMA/Archives journals. Contact: Corey C. Moore, M.D., M.Sc., FRCSC
Public Release: 21-Nov-2011
Archives of DermatologyImportance of treatment process and outcomes varies among patients with psoriasis Among patients with moderate to severe psoriasis, treatment options that are most compatible with their personal and professional life appear to be most important, and treatment location appears more important than probability and magnitude of treatment outcome, according to a report in the November issue of Archives of Dermatology, one of the JAMA/Archives journals. Contact: Wiebke K. Peitsch, M.D.
Public Release: 21-Nov-2011
Archives of DermatologyTreatment of acne using oral antibiotics associated with reporting symptoms of sore throat Taking oral antibiotics for treatment of acne appears to be associated with reporting symptoms of pharyngitis, according to a report published Online First by Archives of Dermatology, one of the JAMA/Archives journals. Contact: Kim Menard
Public Release: 16-Nov-2011
American Heart Association's Scientific Sessions 2011Psoriasis is associated with impaired HDL function, Penn study finds In two new studies presented at the 2011 American Heart Association Scientific Sessions, Penn researchers show that the systemic inflammatory impact of psoriasis may alter both the makeup of cholesterol particles and numbers, as well as impair the function of high density lipoprotein, the "good" cholesterol. Contact: Jessica Mikulski
Public Release: 4-Nov-2011
FASEB JournalProtein causes varicose veins Heidelberg scientists have developed a model for studying varicose veins. Contact: Dr. Gerd Koenig
Public Release: 3-Nov-2011
Current BiologyHuman skin begins tanning in seconds, and here's how We all know that human skin tans after days spent in the sun. That relatively slow process has known links to ultraviolet (and specifically UVB) exposure, which leads to tanning only after it damages the DNA of skin cells. Now, researchers reporting online on Nov. 3 in Current Biology, a Cell Press publication, have uncovered a much speedier path to pigmentation. Contact: Lisa Lyons
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