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Public Release: 21-May-2013
American Thoracic Society 2013 International Conference JAMAResearchers find genetic tie to improved survival time for pulmonary fibrosis Research into genetic features of pulmonary fibrosis by physicians and scientists at the University of Colorado School of Medicine may lead to improved treatment of this deadly lung disease, according to a paper published online by JAMA. 
NIH/National Heart, Lung and Blood Institute
Contact: Mark Couch
Public Release: 21-May-2013
New England Journal of MedicineResearchers find genetic risk factor for pulmonary fibrosis A paper recently published in the New England Journal of Medicine and co-written by physicians and scientists at the University of Colorado School of Medicine finds that an important genetic risk factor for pulmonary fibrosis can be used to identify individuals at risk for this deadly lung disease.
National Institutes of Health, NIH/National Heart, Lung and Blood Institute, US Veterans Administration
Contact: Mark Couch
Public Release: 21-May-2013
American Thoracic Society 2013 International Conference New England Journal of MedicineTonsil surgery improves some behaviors in children with sleep apnea syndrome Children with sleep apnea syndrome who have their tonsils and adenoids removed sleep better, are less restless and impulsive, and report a generally better quality of life, finds a new study funded by the National Institutes of Health. However, the study found cognitive abilities did not improve compared with children who did not have surgery, and researchers say the findings don't mean surgery is an automatic first choice.
National Institutes of Health
Contact: NHLBI Communications
Public Release: 21-May-2013
American Thoracic Society 2013 International Conference New England Journal of MedicineSurgery on adenoid, tonsils improves outcomes in children with obstructive sleep apnea Children with obstructive sleep apnea who had a common surgery to remove their adenoids and tonsils showed notable improvements in behavior, quality of life and other symptoms compared to those treated with "watchful waiting" and supportive care. However, there was no difference between both groups in attention and executive functioning, as measured by formal neuropsychological tests.
National Institutes of Health
Contact: John Ascenzi
Public Release: 21-May-2013
JAMAEarly use of tracheostomy for mechanically ventilated patients not associated with improved survival For critically ill patients receiving mechanical ventilation, early tracheostomy (within the first 4 days after admission) was not associated with an improvement in the risk of death within 30 days compared to patients who received tracheostomy placement after 10 days, according to a study in the May 22/29 issue of JAMA. Contact: Duncan Young, D.M.
Public Release: 21-May-2013
American Thoracic Society 2013 International Conference JAMAGenetic variation among patients with pulmonary fibrosis associated with improved survival Variation in the gene MUC5B among patients with idiopathic pulmonary fibrosis was associated with improved survival, according to a study published online by JAMA. The study is being released early online to coincide with its presentation at the American Thoracic Society international conference. Contact: Mark Couch
Public Release: 21-May-2013
American Thoracic Society 2013 International Conference JAMAShorter duration steroid therapy may offer similar effectiveness in reducing COPD exacerbations Among patients with acute exacerbations of chronic obstructive pulmonary disease requiring hospital admission, a 5-day glucocorticoid treatment course was non-inferior (not worse than) to a 14-day course with regard to re-exacerbation during 6 months of follow-up, according to a study published online by JAMA. The authors write that these findings support a shorter-course glucocorticoid treatment regimen, which would reduce glucocorticoid exposure and the risk of possible adverse effects. Contact: Jorg D. Leuppi
Public Release: 21-May-2013
American Thoracic Society 2013 International ConferenceTreatment with A1-PI slows the progression of emphysema in Alpha-1 antitrypsin deficiency Treatment with an Alpha-1 proteinase inhibitor, a naturally occurring protein that protects lung tissue from breakdown and protects the lung's elasticity, is effective in slowing the progression of emphysema in patients with Alpha-1 antitrypsin deficiency, a life-threatening genetic disorder, according to a new study presented at the 2013 American Thoracic Society International Conference. Contact: Nathaniel Dunford
Public Release: 21-May-2013
American Thoracic Society 2013 International ConferenceExercise levels may predict hospitalizations in COPD population Clinical measurement of physical activity appears to be an independent predictor of whether or not patients with chronic obstructive pulmonary disease (COPD) will end up being hospitalized, according to a new study conducted by researchers in Connecticut. The study also corroborates an earlier investigation that linked higher levels of inactivity with an increased incidence of hospitalizations among patients with COPD. Contact: Nathaniel Dunford
Public Release: 21-May-2013
American Thoracic Society 2013 International ConferenceLow radiation scans help identify cancer in earliest stages A study of veterans at high risk for developing lung cancer shows that low-dose computed tomography (LDCT) can be highly effective in helping clinicians spot tiny lung nodules which, in a small number of patients, may indicate the earliest stages of the disease. LDCT uses less than a quarter of the radiation of a conventional CT scan. Contact: Nathaniel Dunford
Public Release: 21-May-2013
American Thoracic Society 2013 International ConferenceInflammation is associated with depression in COPD patients Depression is common in patients with chronic obstructive pulmonary disease (COPD) and has been linked with disease severity and impaired quality of life. Now, for the first time, researchers at the University of Pittsburgh have linked the systemic inflammation associated with COPD with depression in these patients. Contact: Nathaniel Dunford
Public Release: 21-May-2013
American Thoracic Society 2013 International ConferenceStudy shows COPD is associated with significant and persistent pain Chronic obstructive pulmonary disease is primarily associated with the respiratory symptoms that are its hallmark, but in fact, patients who struggle with the disease also experience significant amounts of chronic pain. A new study conducted by researchers in Pennsylvania and New Mexico estimates the degree of pain suffered by these patients to be close to that experienced by patients with osteoarthritis and rheumatoid arthritis. Contact: Nathaniel Dunford
Public Release: 21-May-2013
American Thoracic Society 2013 International ConferenceAsthma symptoms impair sleep quality and school performance in children The negative effects of poorly controlled asthma symptoms on sleep quality and academic performance in urban schoolchildren has been confirmed in a new study. Contact: Nathaniel Dunford
Public Release: 21-May-2013
American Thoracic Society 2013 International ConferenceAntibiotic therapy appears beneficial for patients with COPD Extended use of a common antibiotic may prolong the time between hospitalizations for patients suffering from chronic obstructive pulmonary disease, according to a post-hoc analysis of a multicenter study which compared the hospitalization rates of patients treated with a 12-month course of azithromycin to the rates of those treated with placebo. Contact: Nathaniel Dunford
Public Release: 21-May-2013
American Thoracic Society 2013 International ConferenceRace and gender influence diagnosis of COPD African-Americans are less likely than whites and women are more likely than men to have had a prior diagnosis of chronic obstructive pulmonary disease regardless of their current disease severity, according to a new study. Contact: Nathaniel Dunford
Public Release: 21-May-2013
American Thoracic Society 2013 International ConferenceRacial disparities in the surgical management of non-small cell lung cancer The surgical management of non-small cell lung cancer in US hospitals varies widely depending on the race of the patient, according to a new study. Contact: Nathaniel Dunford
Public Release: 20-May-2013
JAMA Internal MedicineBronchodilators appear associated with increased risk of cardiovascular events A study of older patients with chronic obstructive pulmonary disease suggests that new use of the long-acting bronchodilators β-agonists and anticholinergics was associated with similar increased risks of cardiovascular events, according to a study published Online First by JAMA Internal Medicine, a JAMA Network publication. Contact: Deborah Creatura
Public Release: 20-May-2013
American Thoracic Society 2013 International Conference JAMAMusic therapy reduces anxiety, use of sedatives for patients receiving ventilator support Among intensive care unit patients receiving acute ventilatory support for respiratory failure, use of patient-preferred music resulted in greater reduction in anxiety and sedation frequency and intensity compared with usual care, according to a study published online by JAMA. The study is being released early online to coincide with its presentation at the American Thoracic Society international conference. Contact: Kathryn Kelley
Public Release: 20-May-2013
American Thoracic Society International Conference JAMAListening to favorite music lowers anxiety, sedation in ICU patients on ventilators New research suggests that for some hospitalized ICU patients on mechanical ventilators, using headphones to listen to their favorite types of music could lower anxiety and reduce their need for sedative medications.
NIH/National Institute of Nursing Research
Contact: Linda Chlan
Public Release: 20-May-2013
American Thoracic Society 2013 International ConferenceCombined wood and tobacco smoke exposure increases risk and symptoms of COPD People who are consistently exposed to both wood smoke and tobacco smoke are at a greater risk for developing chronic obstructive pulmonary disease and for experiencing more frequent and severe symptoms of the disease, as well as more severe airflow obstruction, than those who are exposed to only one type of smoke, according to the results of a new population-based study conducted by researchers in Colombia. Contact: Nathaniel Dunford
Public Release: 20-May-2013
American Thoracic Society 2013 International ConferenceStress test may help predict increased mortality risk in sleep apnea patients Many studies have shown that men and women who suffer from obstructive sleep apnea (OSA) -- a disorder that causes breathing to halt intermittently during sleep -- have a higher mortality rate than those who do not have the disorder. Now, a study from researchers at the Cleveland Clinic shows that OSA patients who also have poor functional capacity have an even greater risk of mortality. Contact: Nathaniel Dunford
Public Release: 20-May-2013
American Thoracic Society 2013 International ConferenceNew study identifies risk factors for depression among COPD patients Patients suffering from chronic obstructive pulmonary disease (COPD) typically suffer from depression more frequently than those without COPD, resulting in higher levels of disability and illness and increasing the overall healthcare burden for the COPD population. Now, a study from researchers in Argentina indicates female COPD patients and patients who experience significant shortness of breath may have the greatest risk for developing depression. Contact: Nathaniel Dunford
Public Release: 20-May-2013
American Thoracic Society 2013 International ConferenceSource of infection affects hospital mortality in septic shock patients in the ICU In ICU patients who have septic shock, the anatomic source of infection has a strong effect on the chances of survival, according to a new study from researchers in Canada. Contact: Nathaniel Dunford
Public Release: 20-May-2013
American Thoracic Society 2013 International ConferenceExposure to traffic pollution increases asthma severity in pregnant women Air pollutants from traffic are associated with increased asthma severity levels in pregnant asthmatic women, according to a new study. Contact: Nathaniel Dunford
Public Release: 20-May-2013
American Thoracic Society 2013 International ConferenceTiny, implantable coil promises hope for emphysema patients A small, easily implantable device called the Lung Volume Reduction Coil may play a key role in the treatment of two types of emphysema, according to a study conducted in Europe. Results of the study indicate the beneficial effects of the device persist more than a year after initial treatment. Contact: Nathaniel Dunford
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