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Biology
Key: Meeting Journal Funder Dissertation
Public Release: 9-Feb-2010
Ecology Letters
New UC Davis study: Climate 'tipping points' may arrive without warning, says top forecaster
A new University of California, Davis, study by a top ecological forecaster says it is harder than experts thought to predict when sudden shifts in Earth's natural systems will occur -- a worrisome finding for scientists trying to identify the tipping points that could push climate change into an irreparable global disaster.
National Science Foundation

Contact: Alan Hastings
amhastings@ucdavis.edu
530-752-8116
University of California - Davis

Public Release: 9-Feb-2010
PLoS Pathogens
Adapting to clogged airways makes common pathogen resist powerful drugs
Mutations of a common environmental pathogen that causes chronic lung disease in patients with cystic fibrosis are able to survive in oxygen-poor, nitrate-rich airway secretions. This same survival mechanism also enables the mutate bacteria to resist the effects of certain antibiotics -- even without any previous exposure to antibiotics.
Cystic Fibrosis Foundation, National Institutes of Health, National Science Foundation

Contact: Leila Gray
leilag@u.washington.edu
206-685-0381
University of Washington

Public Release: 9-Feb-2010
American Journal of Clinical Nutrition
Multicenter study finds little effect of soy isoflavones on bone loss in postmenopausal women
Results from a new multicenter clinical trial of 224 postmenopausal women questions the value of consuming soy isoflavone tablets to help lessen bone loss and minimize the effect of osteoporosis.
NIH/National Institute of Arthritis, Musculoskeletal and Skin Diseases

Contact: Mike Ferlazzo
ferlazzo@iastate.edu
515-294-8986
Iowa State University

Public Release: 9-Feb-2010
Proceedings of the National Academy of Sciences
Cells can read damaged DNA without missing a beat
Under certain growth-limiting conditions, enzymes that read DNA can skim through damaged DNA without skipping any letters in the genetic "text." This suggests a mechanism that can allow bacteria to develop resistance to antibiotics.
National Institutes of Health

Contact: Vince Dollard
404-778-4580
Emory University

Public Release: 9-Feb-2010
Molecular Ecology
Great tits: birds with character
An important part of individual differences within species is due to variation in the underlying genes. One gene, the dopamine receptor D4 gene, however, is known to influence novelty seeking and exploration behaviour in a range of species, including humans and birds. Researchers of the Max Planck Institute for Ornithology in Seewiesen now show that the gene's influence on birds' behavior differs markedly between wild populations of great tits.
Max Planck Society

Contact: Bart Kempenaers
b.kempenaers@orn.mpg.de
49-081-579-32334
Max-Planck-Gesellschaft

Public Release: 9-Feb-2010
Journal of Insect Physiology
Resistant wheat goes for the gut to protect against Hessian flies
Resistant wheat plants stave off attacks by Hessian fly larvae by essentially destroying the fly's midgut and its ability to absorb nutrients, according to a study by Purdue University and the US Department of Agriculture.
US Department of Agriculture ARS Crop Production and Pest Control Research Unit

Contact: Brian Wallheimer
bwallhei@purdue.edu
765-496-2050
Purdue University

Public Release: 9-Feb-2010
Molelcular Immunology
Research could lead to way to halt deadly immune response
Scientists have published new details of their research into the complement reaction, an immune system response that kills thousands annually. The study is published in the journal Molecular Immunology.

Contact: Doug Gardner
gardneda@evms.edu
757-446-6073
Eastern Virginia Medical School

Public Release: 9-Feb-2010
FASEB Journal
The biggest loser: Maternal obesity puts a load on her offspring that lasts a lifetime
As if there are not enough reasons for obese people to lose weight, a research report recently published online in The FASEB Journal, adds several more. In a study involving rats, Duke University researchers found that obesity in mothers causes cellular programming in utero that predisposes offspring to inflammation-related disorders (such as Alzheimer's, Parkinson's, type 2 diabetes, stroke, heart disease and more) from birth, regardless of whether or not the offspring are obese themselves.

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology

Public Release: 9-Feb-2010
Human Mutation
Comprehensive study using bioinformatics predicts the molecular causes of many genetic diseases
It is widely known that genetic mutations cause disease. What are largely unknown are the mechanisms by which these mutations wreak havoc at the molecular level, giving rise to clinically observable symptoms in patients. Now a new study using bioinformatics, led by scientists at the Buck Institute for Age Research, reports the ability to predict the molecular cause of many inherited genetic diseases. These predictions have led to the creation of a web-based tool available to academic researchers who study disease.
National Science Foundation, Indiana University Biomedical Council, Indiana University, Showalter Trust, Indiana Genomics Initiative

Contact: Kris Rebillot
krebillot@buckinstitute.org
415-209-2080
Buck Institute for Age Research

Public Release: 9-Feb-2010
JAMA
Certain genetic profiles associated with recurrence-free survival for non-small cell lung cancer
An analysis of genetic and clinical data for nearly 800 patients with non-small cell lung cancer has identified differences in genetic characteristics that are associated with age and sex specific patterns of increased or decreased recurrence-free survival, according to a study in the Feb. 10 issue of JAMA.

Contact: Michelle Gailiun
michelle.gailiun@duke.edu
919-660-1306
JAMA and Archives Journals

Public Release: 9-Feb-2010
62nd AAN Annual Meeting
Drinking milk during pregnancy may lower baby's risk of MS
Drinking milk during pregnancy may help reduce your baby's chances of developing multiple sclerosis as an adult, according to a preliminary study released today that will be presented at the American Academy of Neurology's 62nd Annual Meeting in Toronto April 10-17, 2010.

Contact: Rachel Seroka
rseroka@aan.com
651-695-2738
American Academy of Neurology

Public Release: 8-Feb-2010
Proceedings of the National Academy of Sciences
Study challenges bird-from-dinosaur theory of evolution – was it the other way around?
A new study just published in the Proceedings of the National Academy of Sciences provides yet more evidence that birds did not descend from ground-dwelling theropod dinosaurs, experts say, and continues to challenge decades of accepted theories about the evolution of flight.

Contact: John Ruben
rubenj@science.oregonstate.edu
541-737-5347
Oregon State University

Public Release: 8-Feb-2010
Proceedings of the National Academy of Sciences
Study reveals new details on the dangers of third-hand smoke
Nicotine in third-hand smoke, the residue from tobacco smoke that clings to virtually all surfaces long after a cigarette has been extinguished, reacts with the common indoor air pollutant nitrous acid to produce dangerous carcinogens. This new potential health hazard was revealed in a multi-institutional study led by researchers with the Lawrence Berkeley National Laboratory.
University of California

Contact: Lynn Yarris
lcyarris@lbl.gov
510-486-5375
DOE/Lawrence Berkeley National Laboratory

Public Release: 8-Feb-2010
Global Change Biology
Will earlier springs throw nature out of step?
The recent trend towards earlier UK springs and summers has been accelerating, according to a study published today in the scientific journal Global Change Biology. The collaborative study, involving scientists from 12 UK research institutions, universities and conservation organisations, is the most comprehensive and rigorous assessment so far of long-term changes in the seasonal timing of biological events across marine, freshwater and terrestrial environments in the UK.
Natural Environment Research Council

Contact: Barnaby Smith
bpgs@ceh.ac.uk
44-792-029-5384
Centre for Ecology & Hydrology

Public Release: 8-Feb-2010
Proceedings of the National Academy of Sciences
Brown biologist solves mystery of tropical grasses' origin
Brown University biologist Erika Edwards and a colleague have found that rainfall, not temperature, was the primary trigger for the evolutionary beginnings of C4 tropical grasses. Their results are published in the Proceedings of the National Academy of Sciences.

Contact: Richard Lewis
Richard_Lewis@Brown.edu
401-863-3766
Brown University

Public Release: 8-Feb-2010
Proceedings of the National Academy of Sciences
Caltech neuroscientists discover brain area responsible for fear of losing money
Neuroscientists at the California Institute of Technology and their colleagues have tied the human aversion to losing money to a specific structure in the brain -- the amygdala.
Gordon and Betty Moore Foundation, Human Frontier Science Program, Wellcome Trust, National Institutes of Health, Simons Foundation, Global Center of Excellence Grant

Contact: Kathy Svitil
ksvitil@caltech.edu
626-395-8022
California Institute of Technology

Public Release: 8-Feb-2010
Genome Research
Method of the future uses single-cell imaging to identify gene interactions
Cellular imaging offers a wealth of data about how cells respond to stimuli, but harnessing this technique to study biological systems is a daunting challenge. In a study published online in Genome Research, researchers have developed a novel method of interpreting data from single-cell images to identify genetic interactions within biological networks, offering a glimpse into the future of high-throughput cell imaging analysis.
US Department of Energy, Leukemia and Lymphoma Society, National Institutes of Health, Howard Hughes Medical Institute

Contact: Peggy Calicchia
calicchi@cshl.edu
516-422-4012
Cold Spring Harbor Laboratory

Public Release: 8-Feb-2010
Cancer Epidemiology, Biomarkers & Prevention
Soft drink consumption may increase risk of pancreatic cancer
Increased sugar intake may stimulate tumor growth through effects of insulin. Pancreatic cancer rates increased nearly twofold over the past several decades. Drinking two or more soft drinks a week led to an 87 percent increased risk.

Contact: Jeremy Moore
jeremy.moore@aacr.org
267-646-0557
American Association for Cancer Research

Public Release: 8-Feb-2010
Journal of the Science of Food and Agriculture
Research reveals link between beer and bone health
A new study suggests that beer is a significant source of dietary silicon, a key ingredient for increasing bone mineral density. Details of this study are available in the February issue of the Journal of the Science of Food and Agriculture, published by Wiley-Blackwell on behalf of the Society of Chemical Industry.

Contact: Dawn Peters
physicalsciencenews@wiley.com
781-388-8408
Wiley-Blackwell

Public Release: 8-Feb-2010
62nd AAN Annual Meeting
Mediterranean diet may lower risk of brain damage that causes thinking problems
A Mediterranean diet may help people avoid the small areas of brain damage that can lead to problems with thinking and memory, according to a study released today that will be presented at the American Academy of Neurology's 62nd Annual Meeting in Toronto April 10-17, 2010.

Contact: Rachel Seroka
rseroka@aan.com
651-695-2738
American Academy of Neurology

Public Release: 8-Feb-2010
Autism Research
UC Davis study confirms link between advanced maternal age and autism
Advanced maternal age is linked to a significantly elevated risk of having a child with autism, regardless of the father's age, according to an exhaustive study of all births in California during the 1990s by UC Davis Health System researchers.
NIH/National Institute of Environmental Health Sciences, US Environmental Protection Agency, UC Davis School of Medicine and Office of Graduate Studies

Contact: Phyllis Brown
phyllis.brown@ucdmc.ucdavis.edu
916-734-9023
University of California - Davis - Health System

Public Release: 8-Feb-2010
Cancer Epidemiology, Biomarkers & Prevention
More smokers than non-smokers accept HPV vaccination for their daughters
A parent's existing health habits or behaviors, like cigarette smoking, may influence the likelihood that they will have their daughters vaccinated against HPV.

Contact: Tara Yates
tara.yates@aacr.org
267-646-0558
American Association for Cancer Research

Public Release: 8-Feb-2010
Disease Models & Mechanisms
A potent suppressor of endometrial cancer is revealed
Treatment of endometrial cancer has not advanced significantly in 30 years and there are no screening tests to promote early detection. Researchers at the University of Texas Southwestern Medical Center and Harvard Medical School developed a new approach to specifically target genetic changes to the endometrial cells in mice. Using this new technique, they show that loss of an emerging tumor suppressor causes abnormal growth and widespread malignancy of cells lining the uterus.

Contact: Kristy Kain
kristy.kain@vanderbilt.edu
615-343-1298
The Company of Biologists

Public Release: 8-Feb-2010
Disease Models & Mechanisms
Mice shed new light on causes of childhood deafness
Mice with a genetic change that causes progressive hearing loss in children, also have hearing loss because sound waves are not processed properly. The ear's attempts to compensate for hearing loss may, ironically, cause further damage leading to complete hearing loss. These mice will allow detailed research into many forms of deafness, and bring closer the prospects of therapies to slow or halt hearing loss in both children and adults.

Contact: Kristy Kain
kristy.kain@vanderbilt.edu
615-343-1298
The Company of Biologists

Public Release: 8-Feb-2010
Cancer Epidemiology, Biomarkers & Prevention
Few women take tamoxifen to prevent breast cancer
Less than a quarter of one percent of women took tamoxifen in 2000 and 2005 to prevent breast cancer. Further research is recommended to explore explanations for the drug's low use.

Contact: Tara Yates
tara.yates@aacr.org
267-646-0558
American Association for Cancer Research