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Public Release: 14-May-2008
American Journal of Nursing
Research examines factors in delaying or declining total knee replacement surgery
A study led by Dr. Ann F. Jacobson, associate professor in Kent State's College of Nursing, unveils the reasons why people may initially choose to postpone but ultimately undergo total knee replacement surgery and emphasizes the need for better patient education before and after the procedure. Study results identified four overarching themes in patients' experiences of total knee replacement, which the researchers named "putting up and putting off," "waiting and worrying," "letting go and letting in," and "hurting and hoping."
Contact: Rachel Wenger-Pelosi
rwenger@kent.edu
330-672-8046
Kent State University
Public Release: 14-May-2008
Weill Cornell science briefs May 2008
Weill Cornell Science Briefs is an electronic newsletter published by the Office of Public Affairs that focuses on innovative medical research and patient care at Weill Cornell Medical College and NewYork-Presbyterian Hospital/Weill Cornell Medical Center. The newsletter is sent electronically to journalists and available to all on this Web site.
Contact: Andrew Klein
ank2017@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Public Release: 14-May-2008
American Journal of Gastroenterology
New treatment for hepatitis C
A statin drug used to lower cholesterol found to stop hepatitis C, especially in patients resistant to standard treatment.
US Veterans Administration, University of Oklahoma College of Medicine
Contact: Diane Clay
diane-clay@ouhsc.edu
405-271-2323
University of Oklahoma
Public Release: 14-May-2008
nternational Journal of Sport Finance
Racism not an issue in firing of NBA coaches
Race is not a factor in the firing of NBA coaches, although white coaches with losing records had somewhat longer tenures before being fired than African-American coaches with more losses than wins, a new study shows.
Contact: Laura Bailey
baileym@umich.edu
734-647-1848
University of Michigan
Public Release: 14-May-2008
Families shed light on likely causative gene for Alzheimer's
The genetic profile of two large Georgia families with high rates of late-onset Alzheimer's disease points to a gene that may cause the disease, researchers say.
Contact: Toni Baker
tbaker@mcg.edu
706-721-4421
Medical College of Georgia
Public Release: 14-May-2008
Taking on Britain's 'sick note culture'
GPs should lend a hand to beat the 'sick note culture' that sees millions of working days lost every year, according to a survey of smaller business owners.
Contact: Tim Utton
tim.utton@nottingham.ac.uk
44-011-584-68092
University of Nottingham
Public Release: 14-May-2008
Archives of Sexual Behavior
Female sex offenders often have mental problems
Women who commit sexual offenses are just as likely to have mental problems or drug addictions as other violent female criminals. This according to the largest study ever conducted of women convicted of sexual offenses in Sweden.
Contact: Katarina Sternudd
katarina.sternudd@ki.se
46-852-483-895
Karolinska Institutet
Public Release: 14-May-2008
Cell Host & Microbe
Common bacteria activating natural killer T cells may cause autoimmune liver disease
A bacteria commonly found in soil and water triggered autoimmune symptoms in mice similar to those found in an incurable liver disease called Primary Biliary Cirrhosis. Reporting their findings in the May 15 Cell Host & Microbe, the multi-institutional research team said injecting laboratory mice with the bacterium -- Novosphingobium aromaticivorans -- prompted activation of natural killer T cells, which were critical to initiating autoimmune processes that led to liver disease.
Lupus Research Institute, University of Chicago Digestive Diseases Research Core Center, Juvenile Diabetes Research Foundation, Wellcome Trust
Contact: Nick Miller
nicholas.miller@cchmc.org
513-803-6035
Cincinnati Children's Hospital Medical Center
Public Release: 14-May-2008
Innovative antennae may signal a 'new wave' in health care provision
Compact, wireless and power efficient body sensors that allow doctors to monitor illnesses and injuries remotely are a step closer thanks to new research.
Contact: Natasha Richardson
natasha.richardson@epsrc.ac.uk
44-017-934-44404
Engineering and Physical Sciences Research Council
Public Release: 14-May-2008
Cephalalgia
Office initiative reduces headaches and neck and shoulder pain by more than 40 percent
When office staff took part in a workplace educational and physical initiative, headaches fell by 41 percent, neck and shoulder pain fell by 43 percent and painkiller use fell by 51 percent. Researchers taught staff office and home relaxation techniques and provided red stickers to place around the workplace to avoid excessive contraction of the head and shoulder muscles. 169 staff were in the intervention group with 175 in the control group. All kept daily diaries.
Contact: Annette Whibley
wizard.media@virgin.net
Wiley-Blackwell
Public Release: 14-May-2008
Discovery of cell linked to learning and memory
Queensland Brain Institute neuroscientists at The University of Queensland have discovered a fundamental component of the process that regulates memory formation.
Contact: Ron Hohenhaus
r.hohen@uq.edu.au
61-733-466-414
Research Australia
Public Release: 14-May-2008
Neuropsychopharmacology
Research sheds new light on heroin addiction
Researchers from the Howard Florey Institute in Melbourne have identified a factor that may contribute towards the development of heroin addiction by manipulating the adenosine A2A receptor, which plays a major role in the brain's 'reward pathway.'
Contact: Merrin Rafferty
merrin.rafferty@florey.edu.au
61-383-441-658
Research Australia
Public Release: 14-May-2008
American Journal of Physiology: Reg, Integrative & Comp Physiology
Mouse study: When it comes to living longer, it's better to go hungry than go running
A study investigating aging in mice has found that hormonal changes that occur when mice eat significantly less may help explain an already established phenomenon: a low calorie diet can extend the lifespan of rodents, a benefit that even regular exercise does not achieve.
UAB Center for Aging
Contact: Christine Guilfoy
cguilfoy@the-aps.org
301-634-7253
American Physiological Society
Public Release: 14-May-2008
International Journal of Cancer
Research shows HPV testing offers women protection for twice as long as smear testing
The long term findings of a study carried out at Hammersmith hospital reveal that testing for human papilloma virus can be twice as effective at protecting women from developing cervical abnormalities as smear testing. Results of the research -- led by professor Jack Cuzick of Barts and The London School of Medicine and Dentistry -- are published today in the International Journal of Cancer.
Contact: Alex Fernandes
a.fernandes@qmul.ac.uk
020-788-27910
Queen Mary, University of London
Public Release: 14-May-2008
Cancer Epidemiology Biomarkers & Prevention
Tooth loss strongly linked to risk of esophageal, head and neck, and lung cancer
Studying thousands of patients, Japanese researchers have found a strong link between tooth loss and increased risk of three cancers -- esophageal, head and neck, and lung. They suggest that preservation of teeth may decrease risk of developing these diseases.
Contact: Jeremy Moore
Jeremy.moore@aacr.org
267-646-0557
American Association for Cancer Research
Public Release: 14-May-2008
Physiological Genomics
Genetic variation linked to sugary food
A new study released today in the online edition of Physiological Genomics finds that individuals with a specific genetic variation consistently consume more sugary foods. The study offers the first evidence of the role that a variation in the GLUT2 gene -- a gene that controls sugar entry into the cells – has on sugar intake, and may help explain individual preferences for foods high in sugar.
Contact: Donna Krupa
DKrupa@the-aps.org
301-634-7209
American Physiological Society
Public Release: 14-May-2008
European Stroke Conference
Researchers fine-tune clot-busting treatment for bleeding in brain
A multicenter study led by Johns Hopkins doctors has fine-tuned the dosage and timing for administering clot-busting tissue plasminogen activator to patients with strokes caused by bleeding within the brain.
FDA Orphan Drug Program, Genentech
Contact: Christen Brownlee
cbrownlee@jhmi.edu
410-955-7832
Johns Hopkins Medical Institutions
Public Release: 14-May-2008
Lancet Oncology
'Cool' new treatment for hot flashes in breast cancer survivors
A "needle to the neck" may be the answer to debilitating hot flashes and sleep disturbances experienced by women who have been treated for breast cancer.
Contact: Patti Davis
patti@davismedpr.com
630-920-8042
DAVIS MEDPR, Inc.
Public Release: 14-May-2008
Cancer Epidemiology, Biomarkers & Prevention
Molecular 'clock' could predict risk for developing breast cancer
A chemical reaction in genes that control breast cancer provides a molecular clock that could one day help researchers more accurately determine a woman's risk for developing breast cancer and provide a new approach for treatment, UT Southwestern Medical Center researchers have found.
American Cancer Society
Contact: Connie Piloto
connie.piloto@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Public Release: 14-May-2008
Nature
New role found for a cardiac progenitor population
In a discovery that could one day lead to an understanding of how to regenerate damaged heart tissue, researchers at the University of California, San Diego have found that parent cells involved in embryonic development of the epicardium -- the cell layer surrounding the outside of the heart -- give rise to three important types of cells with potential for cardiac repair.
National Institutes of Health, American Heart Association
Contact: Debra Kain
ddkain@ucsd.edu
619-543-6163
University of California - San Diego
Public Release: 14-May-2008
New England Journal of Medicine
Most effective initial therapy for HIV-1 infection identified
In the largest study of its kind to evaluate commonly used HIV drugs, researchers at the University of Pittsburgh School of Medicine confirmed that one of the most frequently prescribed triple drug combinations for initial HIV infection is indeed the most effective at suppressing HIV. The study, published in the May 15 issue of New England Journal of Medicine team also found that a two-drug regimen performed comparably to the triple-drug regimens.
NIH/National Institute of Allergy and Infectious Diseases
Contact: Clare Collins
CollCX@upmc.edu
412-647-3555
University of Pittsburgh Schools of the Health Sciences
Public Release: 14-May-2008
New England Journal of Medicine
Aprotinin associated with increased risk of death
Aprotinin is associated with a 50 percent increase in the relative risk of death, according to a major Canadian clinical trial comparing three drugs routinely used to prevent blood loss during heart surgery. The trial, published in the New England Journal of Medicine, shows that approximately six per cent of patients who received aprotinin died within 30 days of surgery compared to four per cent of patients who received tranexamic acid or aminocaproic acid.
Canadian Institutes of Health Research, Ontario Ministry of Health and Long-Term Care
Contact: Jennifer Paterson
jpaterson@ohri.ca
613-798-5555 x19691
Ottawa Health Research Institute
Public Release: 14-May-2008
Genes & Development
Fat chance: Brown vs. white fat cell specification
In the May 15 issue of G&D, Dr. Bruce Spiegelman and colleagues elucidate the molecular pathway that induces cells to become energy-burning brown fat cells as opposed to energy-storing white fat cells.
Contact: Heather Cosel-Pieper
coselpie@cshl.edu
Cold Spring Harbor Laboratory
Public Release: 14-May-2008
Genes & Development
Effect of mutant p53 stability on tumorigenesis and drug design
In the May 15 issue of G&D, Dr. Guillermina Lozano and colleagues reveal how the stabilization of a mutated form of p53 affects oncogenesis, and lends startling new insight into the potential pitfalls of using Mdm2 inhibitors for cancer therapy.
Contact: Heather Cosel-Pieper
coselpie@cshl.edu
Cold Spring Harbor Laboratory
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