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Key: Meeting Journal Funder
Public Release: 22-Aug-2014
Infection Control and Hospital Epidemiology
Penn study: Electronic alerts significantly reduce catheter-associated urinary tract infections
A Penn Medicine team has found that targeted automated alerts in electronic health records significantly reduce urinary tract infections in hospital patients with urinary catheters. In addition, when the design of the alert was simplified, the rate of improvement dramatically increased.

Contact: Lee-Ann Donegan
leeann.donegan@uphs.upenn.edu
215-349-5660
University of Pennsylvania School of Medicine

Public Release: 22-Aug-2014
Journal of Consulting and Clinical Psychology
Study shows cognitive-behavioral coping skills training has positive effects on rheumatoid arthritis
A team of researchers from Wayne State University and collaborators from Duke University Medical Center recently published a paper in the Journal of Consulting and Clinical Psychology that explores two psychological interventions separately and in combination to determine their effectiveness in offering relief to rheumatoid arthritis patients.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research

Public Release: 22-Aug-2014
Journal of Thoracic Oncology
High concordance between EGFR mutations from circulating-free tumor DNA and tumor tissue in non-small cell lung cancer
Epidermal growth factor receptor mutations found in the circulating free tumor DNA from the plasma of advanced non-small cell lung cancer patients correlates well with the epidermal growth factor receptor mutations from patient-matched tumor tissue DNA.

Contact: Rob Mansheim
rob.mansheim@iaslc.org
720-325-2952
International Association for the Study of Lung Cancer

Public Release: 22-Aug-2014
Journal of Thoracic Oncology
Novel oncogenic RET mutation found in small cell lung cancer
For the first time an oncogenic somatic mutation at amino acid 918 in the rearranged during transfection protein has been identified in small cell lung cancer tumors and enforced expression of this mutation within small cell lung cancer tumor cell lines produced increased intracellular signaling and cell growth.

Contact: Rob Mansheim
rob.mansheim@iaslc.org
720-325-2952
International Association for the Study of Lung Cancer

Public Release: 22-Aug-2014
Journal of Thoracic Oncology
Deletion predicts survival in advanced non-small cell lung cancer
Bcl-2-like protein 11 deletion in advanced non-small cell lung cancer is associated with shorter progression free survival in epidermal growth factor receptor tyrosine kinase inhibitor or chemotherapy treated Asian patients. Also, Bcl-2-like protein 11 deletion independently predicts overall survival of advanced non-small cell lung cancer patients.

Contact: Rob Mansheim
rob.mansheim@iaslc.org
720-325-2952
International Association for the Study of Lung Cancer

Public Release: 22-Aug-2014
29th Annual International Papillomavirus Conference
Study shows Hera Therapeutics compound combats HPV types that cause most cervical cancer
Research presented at the 29th Annual International Papillomavirus Conference shows that a therapy being developed by Hera Therapeutics Inc. combats three types of human papillomavirus, including the two that cause 70 percent of all cervical cancer. When tested in several cultured human cell models, HTI-1968 blocked the replication of HPV-16, HPV-18 and HPV-11 cells, according to the NIH-funded research of Louise T. Chow, Ph.D. and Thomas Broker, Ph.D.
National Institute of Allergy and Infectious Diseases

Contact: Terri Somers, Somers Media
terri@somersmedia.com
619-991-2369
Somers Media

Public Release: 22-Aug-2014
NeuroRehabilitation
Kessler Foundation study of self-awareness in MS has implications for rehabilitation
New study by Kessler Foundation researchers shows that persons with MS may be able to improve their self-awareness through task-oriented cognitive rehabilitation. Yael Goverover, et al: 'Metacognitive knowledge and online awareness in persons with multiple sclerosis' was epublished July 2 in NeuroRehabilitation. Self-awareness is one's ability to recognize cognitive problems caused by brain injury. This is the first study of self-awareness in MS that includes assessment of online awareness, as well as metacognitive awareness.
National Multiple Sclerosis Society

Contact: Carolann Murphy
Cmurphy@kesslerfoundation.org
973-324-8382
Kessler Foundation

Public Release: 22-Aug-2014
Cell Death & Disease
New enzyme targets for selective cancer therapies
A University of Alberta team has designed compounds that target brain cancer.

Contact: Bryan Alary
bryan.alary@ualberta.ca
780-492-0436
University of Alberta

Public Release: 22-Aug-2014
Biomaterials
Tissue regeneration using anti-inflammatory nanomolecules
Researchers are working on innovative approaches to tissue regeneration in order to improve the lives of patients with urinary bladder dysfunction.

Contact: Peggy Murphy
pemurphy@luriechildrens.org
773-755-7485
Children's Memorial Hospital

Public Release: 22-Aug-2014
Catheterization and Cardiovascular Interventions
UH Case Medical Center's Dr. Parikh authors SCAI paper on renal artery stenosis treatment
Renal artery stenting to open blockages in the kidney arteries may benefit patients who have historically been excluded from modern clinical trials, according to new recommendations for renal artery stenosis e-published in Catheterization and Cardiovascular Interventions today by the Society for Cardiovascular Angiography and Interventions.

Contact: Mike Ferrari
mike.ferrari@uhhospitals.org
216-844-7239
University Hospitals Case Medical Center

Public Release: 22-Aug-2014
Preventive Medicine
Women with severe, chronic health issues are screened for breast cancer less often
Women with severe disabilities and multiple chronic conditions are screened for breast cancer less often than women with no disabilities or no chronic conditions, a new study has found.

Contact: Geoff Koehler
koehlerg@smh.ca
416-864-6060 x6537
St. Michael's Hospital

Public Release: 22-Aug-2014
Neurosurgery
More common procedures for painful facial tics carry high costs, reports study in Neurosurgery
For patients who need surgery for facial pain caused by trigeminal neuralgia, the most cost-effective procedure is the least often used, reports a study in the September issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

Contact: Connie Hughes
Connie.Hughes@wolterskluwer.com
646-674-6348
Wolters Kluwer Health

Public Release: 22-Aug-2014
Journal of Urban Health
Study identifies challenges faced by NYU nurses after Hurricane Sandy
A study published in The Journal of Urban Health examines the impact on NYULMC nurses' post-Sandy deployment to help address patient surge in eight local hospitals and health facilities that had not been as affected by the storm.
New York University College of Dentistry

Contact: Christopher James
christopher.james@nyu.edu
212-998-6876
New York University

Public Release: 22-Aug-2014
Molecular Nutrition and Food Research
Research underway to create pomegranate drug to stem Alzheimer's and Parkinson's
The onset of Alzheimer's disease can be slowed and some of its symptoms curbed by a natural compound that is found in pomegranate. Also, the painful inflammation that accompanies illnesses such as rheumatoid arthritis and Parkinson's disease could be reduced, according to the findings of a two-year project headed by University of Huddersfield scientist Dr. Olumayokun Olajide, who specialises in the anti-inflammatory properties of natural products.

Contact: Nicola Werritt
n.c.werritt@hud.ac.uk
01-484-473-315
University of Huddersfield

Public Release: 22-Aug-2014
Cancer Epidemiology
Smokers consume same amount of cigarettes regardless of nicotine levels
Cigarettes with very low levels of nicotine may reduce addiction without increasing exposure to toxic chemicals, according to a new study from the University of Waterloo.

Contact: Pamela Smyth
psmyth@uwaterloo.ca
519-888-4777
University of Waterloo

Public Release: 22-Aug-2014
European Journal of Internal Medicine
Many patients are discharged without a diagnosis
New research shows that one out of four acutely admitted medical patients leave the hospital again without getting a diagnosis.

Contact: Christian Fynbo Christian
cc@dce.au.dk
45-20-20-83-98
Aarhus University

Public Release: 22-Aug-2014
PLOS ONE
Scientists uncover why major cow milk allergen is actually allergenic
A specific protein in milk known as beta-lactoglobulin is able to initiate an allergy only when being devoid of iron. Loaded with iron, the protein is harmless. The scientists discovered the same mechanism recently with regard to birch pollen allergy. Their findings help to decipher allergic reactions and were published in the journal PLOS ONE.

Contact: Susanna Kautschitsch
susanna.kautschitsch@vetmeduni.ac.at
43-125-077-1153
University of Veterinary Medicine -- Vienna

Public Release: 22-Aug-2014
Journal of the National Cancer Institute
Scientists map risk of premature menopause after cancer treatment
Women treated for the cancer Hodgkin lymphoma will be able to better understand their risks of future infertility after researchers estimated their risk of premature menopause with different treatments. The findings, set out in the Journal of the National Cancer Institute, are based on the experience of more than 2,000 young women in England and Wales treated for the cancer over a period of more than 40 years.

Contact: Graham Shaw
henry.french@icr.ac.uk
020-715-35380
Institute of Cancer Research

Public Release: 22-Aug-2014
Neuron
The striatum acts as hub for multisensory integration
A new study from Karolinska Institutet in Sweden provides insight on how the brain processes external input such as touch, vision or sound from different sources and sides of the body, in order to select and generate adequate movements. The findings, which are presented in the journal Neuron, show that the striatum acts as a sensory 'hub' integrating various types of sensory information, with specialized functional roles for the different neuron types.
European Research Council, Swedish Research Council, Knut and Alice Wallenberg Foundation, Karolinska Institutet StratNeuro

Contact: Press Office
pressinfo@ki.se
46-852-486-077
Karolinska Institutet

Public Release: 22-Aug-2014
Inflammatory Bowel Diseases
Study shows epigenetic changes in children with Crohn's disease
A new study finds a wide range of epigenetic change -- alterations in DNA across the genome that may be related to key environmental exposures -- in children with Crohn's disease, reports Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

Contact: Connie Hughes
Connie.Hughes@wolterskluwer.com
646-674-6348
Wolters Kluwer Health

Public Release: 22-Aug-2014
Nature Communications
Calcium and reproduction go together
Everyone's heard of the birds and the bees. But that old expression leaves out the flowers that are being fertilized. The fertilization process for flowering plants is particularly complex and requires extensive communication between the male and female reproductive cells. New research reports discoveries in the chemical signaling process that guides flowering plant fertilization.

Contact: Guido Grossman
guido.grossmann@cos.uni-heidelberg.de
Carnegie Institution

Public Release: 22-Aug-2014
PLOS ONE
From happiness to pain: Understanding serotonin's function
In a study published Aug. 22 in the scientific journal PLOS ONE, researchers at the Champalimaud Neuroscience Programme establish the effect of serotonin on sensitivity to pain using a combination of advanced genetic and optical techniques.

Contact: Maria Joao Soares
mjsoares@jlma.pt
351-914-237-487
JLM&A, SA

Public Release: 22-Aug-2014
Nature Communications
Genetics and lifestyle have a strong impact on biomarkers for inflammation and cancer
In a new study published in Nature Communications, research scientists from Uppsala University present for the first time a large-scale study of the significance of genetic, clinical and lifestyle factors for protein levels in the bloodstream. The results of the study show that genetics and lifestyle are determining factors for protein levels, a discovery which greatly influences the possibilities for using more biomarkers to identify disease.

Contact: Stefan Enroth
stefan.enroth@igp.uu.se
46-018-471-4913
Uppsala University

Public Release: 21-Aug-2014
Brain Connectivity
Influenced by self-interest, humans less concerned about inequity to others
Strongly influenced by their self-interest, humans do not protest being overcompensated, even when there are no consequences, researchers in Georgia State University's Brains and Behavior Program have found.
Brains and Behavior Program at Georgia State University

Contact: LaTina Emerson
lemerson1@gsu.edu
404-413-1353
Georgia State University

Public Release: 21-Aug-2014
Diabetes Care
Losing weight lowers health care costs for adults with type 2 diabetes
Overweight individuals with diabetes who lose weight by dieting and increasing their physical activity can reduce their health care costs by an average of more than $500 per year, according to a new study.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, NIH/National Heart, Blood and Lung Institute, Centers for Disease Control and Prevention

Contact: Marguerite Beck
marbeck@wakehealth.edu
336-716-2415
Wake Forest Baptist Medical Center