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Breaking News Public Release: 2-Dec-2012
 Nature Structural & Molecular BiologyScientists at Scripps Research Institute discover how 2 proteins help keep cells healthy Scientists at The Scripps Research Institute have determined how two proteins help create organelles, or specialized subunits within a cell, that play a vital role in maintaining cell health. This discovery opens the door for research on substances that could interfere with the formation of these organelles and lead to new therapies for cancer. 
National Institutes of Health, Japan Science and Technology Agency
Contact: Mika Ono
Public Release: 2-Dec-2012
Nature GeneticsScientists find 'bully' genes in common childhood tumor In a genome sequencing study of 74 neuroblastoma tumors in children, scientists at the Johns Hopkins Kimmel Cancer Center and the Children's Hospital of Philadelphia found that patients with changes in two genes, ARID1A and ARID1B, survive only a quarter as long as patients without the changes. The discovery could eventually lead to early identification of patients with aggressive neuroblastomas who may need additional treatments.
NIH/National Cancer Institute, St. Baldrick's Foundation
Contact: Vanessa Wasta
Public Release: 2-Dec-2012
Nature GeneticsCell surface transporters exploited for cancer drug delivery According to Whitehead Institute researchers, a protein known as monocarboxylate transporter 1 (MCT1), which is highly expressed in a subset of metabolically altered cancer cells, is needed for the entry of the investigational cancer drug 3-bromopyruvate (3-BrPA) into malignant cells. This work may open a new avenue for cancer therapeutic research, as other transport molecules have already been identified on the surface of certain cancer cells.
National Institutes of Health, David H. Koch Institute for Integrative Cancer Research, Jane Coffin Childs Fund, National Science Foundation
Contact: Nicole Rura
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