IMAGE: Lung squamous cell carcinoma

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Controlling Cholesterol Metabolism in Pancreatic Cancer

Controlling Cholesterol Metabolism in Pancreatic Cancer
Researchers have shown how controlling cholesterol metabolism in pancreatic cancer cells reduces metastasis to other organs, pointing to a potential new treatment. Findings showed a higher number of ...

Contact: emil venere
venere@purdue.edu
765-494-4709
Purdue University

Halloysite-Doped Biocomposite Scaffolds

Halloysite-Doped Biocomposite Scaffolds
A sketch demonstrating the fabrication and in vitro and in vivo testing of novel halloysite-doped biopolymer tissue engineering scaffold

Contact: Yevgeniya Litvinova
press@kpfu.ru
7-843-233-7345
Kazan Federal University

Professor Jack Cuzick and the IBIS-II Team

Professor Jack Cuzick and the IBIS-II Team
This is a photograph of Professor Jack Cuzick and the IBIS-II team.

Contact: Joel Winston
j.winston@qmul.ac.uk
44-207-882-7943
Queen Mary University of London

Making Precision Medicine a Reality: Genomics Researchers Find Road Map (2 of 2)

Making Precision Medicine a Reality: Genomics Researchers Find Road Map (2 of 2)
Understanding the genetic and biologic basis of diseases like rheumatoid arthritis, cancer, diabetes and Alzheimer's will lead to new therapies.

Contact: Jean Spinelli
jspinell@email.arizona.edu
520-626-2531
University of Arizona Health Sciences

Repair of DNA Breaks

Repair of DNA Breaks
LINP1 enhances the repair of DNA breaks by serving as a scaffold that links two other proteins in the repair machinery.

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Tumor After Anti-angiogenic Therapy

Tumor After Anti-angiogenic Therapy
Following anti-angiogenic therapy, tumors develop regions containing no blood vessels (green) and therefore no oxygen (red). The tumor cells are made visible by dyeing the nuclei blue.

Contact: Yannik Sprecher
yannik.sprecher@unibas.ch
41-612-672-424
University of Basel

Could a Cancer Drug Be Repurposed for Fragile X Syndrome?

Could a Cancer Drug Be Repurposed for Fragile X Syndrome?
Schematic diagram showing the stages of neurogenesis in the adult dentate gyrus of the hippocampus and cell lineage-specific markers. qNSC, quiescent NSC; aNSC, activated NSC. This material relates to...

Contact: Science Press Package
scipak@aaas.org
202-326-6440
American Association for the Advancement of Science

Duplex-p53-20x

Duplex-p53-20x
In this slide of a Fallopian tube's epithelium, the brown-stained cells "we believe are precursors for ovarian cancers," said Rosana Risques, study co-author.

Contact: Brian Donohue
bdonohue@uw.edu
206-543-7856
University of Washington Health Sciences/UW Medicine

Duplex-p53

Duplex-p53
Among cells stained for the P53 mutation, the brown dots are nuclei of high-grade serous ovarian cancer cells. The blue represents normal Fallopian tube epithelial cells.

Contact: Brian Donohue
bdonohue@uw.edu
206-543-7856
University of Washington Health Sciences/UW Medicine

Breast Cancer Cells in 3-D Culture

Breast Cancer Cells in 3-D Culture
Detail of breast cancer cells in 3-D culture, collectively invading into the surrounding extracellular matrix.

Contact: Dr. Christina Scheel
christina.scheel@helmholtz-muenchen.de
49-893-187-2012
Helmholtz Zentrum München - German Research Center for Environmental Health

Expenditures on Cancer Drugs

Expenditures on Cancer Drugs
This is the net value from expenditures on cancer drugs in selected North American, European, and Asian Pacific Countries, 2004 and 2014.

Contact: Sue Ducat
sducat@projecthope.org
301-841-9962
Health Affairs

Image of the NuRD Complex

Image of the NuRD Complex
This is an image of the NuRD complex.

Contact: Professor John Schwabe
john.schwabe@le.ac.uk
01-162-297-030
University of Leicester

Microscopic Images of a Mouse Retina

Microscopic Images of a Mouse Retina
On the left the new blood vessels are in branching mode; on the right they are increasing in diameter under the influence of the VEGFA hormone. The cell membrane is colored green, the cell nuclei blue...

Contact: Vera Glaßer
vera.glasser@mdc-berlin.de
49-309-406-2120
Max Delbrück Center for Molecular Medicine in the Helmholtz Association

Comments from Lead Researcher on New ALL Relapse Revention Protocols

Comments from Lead Researcher on New ALL Relapse Revention Protocols
William L. Carroll, M.D., from NYU Langone Medical Center and its Perlmutter Cancer Center discusses the findings from a Journal of Clinical Oncology study showing new protocols to improve relapse ...

Contact: Jim Mandler
jim.mandler@nyumc.org
212-404-3525
NYU Langone Medical Center / New York University School of Medicine

Dr. Haidong Zhu and Dr. Yanbhin Dong, Augusta University

Dr. Haidong Zhu and Dr. Yanbhin Dong, Augusta University
(Left) Dr. Haidong Zhu, molecular geneticist at the Georgia Prevention Institute at the Medical College of Georgia at Augusta University and corresponding author of the study & Dr. Yanbin Dong, ...

Contact: Toni Baker
tbaker@augusta.edu
706-721-4421
Medical College of Georgia at Augusta University

An image of the HDAC Enzyme

An image of the HDAC Enzyme
This is an image of the HDAC enzyme.

Contact: Professor John Schwabe
js336@leicester.ac.uk
01-162-297-030
University of Leicester

Human PDAC Tumors Showing Expressions

Human PDAC Tumors Showing Expressions
Human PDAC tumors shows co-expression of CXCL1 (red) and CK19 (green; a marker of PADC) by confocal microscopy.

Contact: Jim Mandler
jim.mandler@nyumc.org
212-404-3525
NYU Langone Medical Center / New York University School of Medicine

The GS-DProSw Molecule in Its Inactive Form Can Be Activated By Visible Light

The GS-DProSw Molecule in Its Inactive Form Can Be Activated By Visible Light
The GS-DProSw molecule in its inactive form (blue) can be activated by visible light (red) and "switched off" again by UV light.

Contact: Monika Landgraf
presse@kit.edu
49-721-608-47414
Karlsruher Institut für Technologie (KIT)

Microbial Therapy Develop to Fight Cancer

Microbial Therapy Develop to Fight Cancer
Evelo Biosciences has licensed a cancer therapy developed in the laboratory of University of Chicago researcher Thomas Gajewski that employs select gut microbes to boost the immune system's attack on ...

Contact: Steve Koppes
skoppes@uchicago.edu
773-702-8366
University of Chicago

Brain Tumor Stem Cell

Brain Tumor Stem Cell
This is an image of brain tumor stem cell taken by Dr. Takrima Haque in the laboratory of Dr. Arezu Jahani-Asl.

Contact: Amelia Buchanan
ambuchanan@ohri.ca
61-379-855-557-3687
Ottawa Hospital Research Institute

Caveolin-1

Caveolin-1
The "gatekeeper" caveolin-1 (purple-colored in the picture) makes its way to the surface of a stressed cell, and prevents endocytosis, that is, it prevents most proteins from entering the ...

Contact: Cecilia Schubert
cecilia.schubert@kommunikation.lu.se
46-073-062-3858
Lund University

Mattias Belting Produced this Video Illustration

Mattias Belting Produced this Video Illustration
Video illustrates how some of the proteins that are on the surface of a stressed cell and illuminated first reside on the cell's surface and then gradually enters the cell.

Contact: Cecilia Schubert
cecilia.schubert@kommunikation.lu.se
46-073-062-3858
Lund University

Brain Stem Cells

Brain Stem Cells
Neural stem cells (red) interact with their niche glial cells (green) to remain in quiescence.

Contact: Dr. Christian Berger
bergerc@uni-mainz.de
49-613-139-24328
Johannes Gutenberg Universitaet Mainz

PLK4 Induced Aster Formation

PLK4 Induced Aster Formation
PLK4 induced aster formation around centrioles.

Contact: Vanessa Borges
vborges@igc.gulbenkian.pt
Instituto Gulbenkian de Ciencia

Pancreatic Mouse Model

Pancreatic Mouse Model
A form of immunotherapy shows promise against pancreatic cancer in a mouse model. The scientists engineered T cells to recognize pancreatic cancer cells -- the cells homed to mice's tumors within a ...

Contact: Rhonda Curry
rcurry@fredhutch.org
206-240-6011
Fred Hutchinson Cancer Research Center

Pembrolizumab Image

Pembrolizumab Image
Multispectral immunofluorescence shows the interface between Merkel cell tumor cells (orange) and host immune cells (yellow marks CD8+ lymphocytes, red marks CD68+ macrophages). Cell-surface PD-L1 ...

Contact: Rhonda Curry
rcurry@fredhutch.org
206-240-6011
Fred Hutchinson Cancer Research Center

Cancer Cell Sliding Behavior

Cancer Cell Sliding Behavior
This video shows a breast cancer cell sliding past another cell.

Contact: Joseph Caputo
jcaputo@cell.com
617-397-2802
Cell Press

Cancer Cell Reversing Direction

Cancer Cell Reversing Direction
This video shows a breast cancer cell reversing direction.

Contact: Joseph Caputo
jcaputo@cell.com
617-397-2802
Cell Press

REVEALER

REVEALER
To better characterize the functional context of genomic variations in cancer, researchers developed a new computer algorithm called REVEALER.

Contact: Heather Buschman
hbuschman@ucsd.edu
619-543-6163
University of California - San Diego

Cellular Trojan Horse Yields Potential Cancer Treatment

Cellular Trojan Horse Yields Potential Cancer Treatment
Confocal microscopy image of stem cells loaded with drug containing polymeric microparticles.

Contact: Haley Bridger
hbridger@partners.org
617-525-6383
Brigham and Women's Hospital

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