IMAGE: Lung squamous cell carcinoma

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Sediba Vertebra

Sediba Vertebra
This image shows the sixth thoracic vertebra of juvenile Australopithecus sediba. Top row shows surface rendered image volume. Bottom row shows partially transparent image volume with the ...

Contact: Schalk Mouton
schalk.mouton@wits.ac.za
27-827-399-637
University of the Witwatersrand

Metatarsal Cancer

Metatarsal Cancer
Metatarsal (a) and (b) surface rendered models show medullary spongy bone infill and clear focalized cortical destruction near the periosteal margin; also evident on external cortical margin directly ...

Contact: Schalk Mouton
schalk.mouton@wits.ac.za
27-827-399-637
University of the Witwatersrand

Earliest Cancer on Hominin

Earliest Cancer on Hominin
Volume rendered image of the external morphology of the foot bone shows the extent of expansion of the primary bone cancer beyond the surface of the bone.

Contact: Schalk Mouton
schalk.mouton@wits.ac.za
27-827-399-637
University of the Witwatersrand

Internet Research Not Reaching Everyone

Internet Research Not Reaching Everyone
The government has begun what's called the Precision Medicine Initiatve, an effort to eventually tailor medical care to individual patients and their individual genetic traits. And as that process ...

Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine

Online

Online
Researchers at Washington University School of Medicine in St. Louis found that fewer than half of European-American people who were asked to go to a website as part of a medical research study ever ...

Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine

cGVHD 3 Years after Bone Marrow Transplant

cGVHD 3 Years after Bone Marrow Transplant
University of Colorado Cancer Center study shows reduced chronic graft-versus-host disease with cord blood, compared with blood from unrelated matched donor, three years after bone marrow transplant.

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Anschutz Medical Campus

Making Pancreas Organoids to Test New Therapies

Making Pancreas Organoids to Test New Therapies
New knowledge about pancreatic cancer obtained by members of the Tuveson lab was made possible in significant part by their ability to grow pancreas organoids -- spherical accumulations of ductal ...

Contact: Peter Tarr
tarr@cshl.edu
516-367-5055
Cold Spring Harbor Laboratory

The Power of a Combined Drug Treatment in Pancreas Cancer

The Power of a Combined Drug Treatment in Pancreas Cancer
In tissue sampled from the pancreas of mice that model pancreatic cancer, brown spots stain cells that are dividing rapidly -- a hallmark of cancer progression. The lower image, in mice having ...

Contact: Peter Tarr
tarr@cshl.edu
516-367-5055
Cold Spring Harbor Laboratory

Slowing down Cell Division in Pancreas Cancer

Slowing down Cell Division in Pancreas Cancer
Brown staining in these images marks cancerous mouse pancreas cells in which the AKT pathway, which governs protein synthesis, is activated. Upper left: untreated tissue. Lower left: tissue after ...

Contact: Peter Tarr
tarr@cshl.edu
516-367-5055
Cold Spring Harbor Laboratory

<em>C. elegans</em> with Defective eri-1 Gene

C. elegans with Defective eri-1 Gene

Roundworms (Caenorhabditis elegans) with a disabled eri-1 gene can lose their ability to control repetitive DNA. In the absence of eri-1, even two age-matched siblings ...

Contact: Matthew Wright
mewright@umd.edu
301-405-9267
University of Maryland

Quantitating the Complete Human Proteome

Quantitating the Complete Human Proteome
This is an illustration of SRM peaks and a human face.

Contact: Hsiao-Ching Chou
hchou@systemsbiology.org
206-732-2157
Institute for Systems Biology

Regenstrief Institute investigator Thomas F. Imperiale, M.D., Indiana University

Regenstrief Institute investigator Thomas F. Imperiale, M.D., Indiana University
Thomas F. Imperiale, M.D. is a VA, Regenstrief Institute, and Indiana University clinician-researcher.

Contact: Cindy Fox Aisen
caisen@iupui.edu
317-843-2275
Indiana University

Drugs Deliver One-Two Punch Against Resistant Kidney Cancer

Drugs Deliver One-Two Punch Against Resistant Kidney Cancer
Researchers report that a combination of standard chemotherapy and an epigenetic drug may overcome drug resistance in kidney cancer. This material relates to a paper that appeared in the July 20. 2016...

Contact: Science Press Package
scipak@aaas.org
202-326-6440
American Association for the Advancement of Science

Gene Therapy Staves Off Cancer-Driven Muscle Wasting (2 of 2)

Gene Therapy Staves Off Cancer-Driven Muscle Wasting (2 of 2)
Smad7 gene delivery promotes skeletal muscle hypertrophy in healthy mice. This material relates to a paper that appeared in the July 20, 2016, issue of Science Translational Medicine, ...

Contact: Science Press Package
scipak@aaas.org
202-326-6440
American Association for the Advancement of Science

Gene Therapy Staves Off Cancer-Driven Muscle Wasting (1 of 2)

Gene Therapy Staves Off Cancer-Driven Muscle Wasting (1 of 2)
Muscle-directed gene therapy may protect against muscle wasting associated with advanced cancer, researchers show in mice. This material relates to a paper that appeared in the July 20, 2016, issue of...

Contact: Science Press Package
scipak@aaas.org
202-326-6440
American Association for the Advancement of Science

Fatty Tissue May Be 'Robbers Cave' for Cancer Stem Cells

Fatty Tissue May Be 'Robbers Cave' for Cancer Stem Cells
Study shows that cancer stem cells may hide in fatty tissue, even transforming this tissue to help them resist chemotherapy.

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Anschutz Medical Campus

Silicon Nanoparticles

Silicon Nanoparticles
Left: Schematic representation of silicon nanoparticles (SiNPs) biodegradation processes: (I) localization of SiNPs on the cell membrane; (II) penetration of SiNPs in the cytoplasm with partial ...

Contact: Vladimir Koryagin
science-release@rector.msu.ru
Lomonosov Moscow State University

Synthetic Cell Wiring

Synthetic Cell Wiring
This image represents synthetic lethal wiring of a cancer cell, with previously known interactions in red and newly discovered interactions in gray.

Contact: Heather Buschman
hbuschman@ucsd.edu
858-249-0456
University of California - San Diego

Theresa A. Keresztes, 2016 ASTRO Survivor Circle Award Winner

Theresa A. Keresztes, 2016 ASTRO Survivor Circle Award Winner
Theresa A. Keresztes, 2016 ASTRO Survivor Circle Award Winner

Contact: Erin L. Boyle
erin.boyle@astro.org
703-839-7336
American Society for Radiation Oncology

Functional Units

Functional Units
In the new algorithm, proteins are denoted in a radial-spherical coordinate system, which itself is as close as possible to the shape of the protein. This allows the proteins to be split into "...

Contact: Sergey Divakov
divakov@phystech.edu
Moscow Institute of Physics and Technology

Protein Complex

Protein Complex
The actual structure of a protein complex together with an ensemble of alternative structures selected using the new algorithm.

Contact: Sergey Divakov
divakov@phystech.edu
Moscow Institute of Physics and Technology

Thyroid Cancer

Thyroid Cancer
More imaging after thyroid cancer treatment identifies recurrence, but it does not always improve survival, a new study suggests. Megan Haymart, M.D., and Mousumi Banerjee, Ph.D., discuss.

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Ocean Bacteria

Ocean Bacteria
Marine bacteria Vibrio alginolyticus magnified several thousand times.

Contact: Catriona Kelly
Catriona.Kelly@ed.ac.uk
44-131-651-4401
University of Edinburgh

Turning on T Cells

Turning on T Cells
Researchers imaged cells to identify proteins that affect the expression of a genetic switch for T cells. On the right, T cells where the switch is activated glow in yellow. On the left, the rainbow ...

Contact: Whitney Clavin
wclavin@caltech.edu
626-395-1856
California Institute of Technology

New Structure of a Calcium-Shuttling Molecule Could Help Scientists Target Aggressive Cancers

New Structure of a Calcium-Shuttling Molecule Could Help Scientists Target Aggressive Cancers
Scientists have captured new images of a calcium-shuttling molecule that has been linked to aggressive cancers. The three-dimensional structure could help researchers develop novel therapies and ...

Contact: Lucky Tran
lucky.tran@columbia.edu
212-305-3689
Columbia University Medical Center

New Mass Spectrometry Imaging

New Mass Spectrometry Imaging
A new mass spectrometry imaging protocol allows the analysis of metabolites like Adenosine monophosphate from FFPE tissue, shown here as background.

Contact: Dr. Axel Karl Walch
axel.walch@helmholtz-muenchen.de
49-893-187-2739
Helmholtz Zentrum München - German Research Center for Environmental Health

Contacts with Endoplasmic Reticulum Regulate DNA Synthesis, Division of Mitochondria

Contacts with Endoplasmic Reticulum Regulate DNA Synthesis, Division of Mitochondria
Mitochondria play a vital role in cell health and disease and have their own DNA. New UC Davis research shows that mitochondrial DNA (green spots) is found at points where mitochondria (blue) are in ...

Contact: Andy Fell
ahfell@ucdavis.edu
530-752-4533
University of California - Davis

Enzyme Structure

Enzyme Structure
Panel a: This is a cartoon "ribbon" diagram of the structure of Rumi in complex with the donor substrate UDP-Glucose (UDP-Glc, shown in cyan) and acceptor substrate hFA9 EGF (dark green). ...

Contact: Karen McNulty Walsh
kmcnulty@bnl.gov
631-344-8350
DOE/Brookhaven National Laboratory

Melanoma

Melanoma
The left two columns show resolution of skin lesion samples taken with two conventional types of deep-tissue microscopy. The right column contains images taken with a pump-probe microscope, showing ...

Contact: Anne Ju Manning
anne.manning@colostate.edu
970-491-7099
Colorado State University

Visualization

Visualization
This is a visualization of the coronary vasculature patterning of an adult mouse heart.

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

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