IMAGE: Lung squamous cell carcinoma

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The Mysteries Behind Metabolic Reprograming in Cancer (1 of 1)

The Mysteries Behind Metabolic Reprograming in Cancer (1 of 1)
Metabolic reprogramming is essential for the survival of malignant cancer cells. This material relates to a paper that appeared in the May 27, 2016, issue of Science Advances, published by AAAS...

Contact: Science Advances Press Package Team
vancepak@aaas.org
202-326-6440
American Association for the Advancement of Science

Electroporation Efficiently Drives CRISPR-Cas9 Into Embryos

Electroporation Efficiently Drives CRISPR-Cas9 Into Embryos
Electroporation jolts embryos with electricity to open holes that allow the CRISPR-Cas9 molecule (upper right) to enter and edit the DNA.

Contact: Robert Sanders
rlsanders@berkeley.edu
510-643-6998
University of California - Berkeley

Studying Pancreatic Cancer Cells (1 of 2)

Studying Pancreatic Cancer Cells (1 of 2)
Georgia Tech graduate research assistant Mengnan Zhang examines a solution containing pancreatic cancer cells. The research examined the role of microRNA molecules in controlling resistance to ...

Contact: John Toon
jtoon@gatech.edu
404-894-6986
Georgia Institute of Technology

Studying Pancreatic Cancer Cells (2 of 2)

Studying Pancreatic Cancer Cells (2 of 2)
Georgia Tech graduate research assistant Mengnan Zhang moves samples of pancreatic cancer cells into a flask for study. The research examined the role of microRNA molecules in controlling resistance ...

Contact: John Toon
jtoon@gatech.edu
404-894-6986
Georgia Institute of Technology

Blocking Gateway into Bone May Halt Breast Cancer Spread (3 of 3)

Blocking Gateway into Bone May Halt Breast Cancer Spread (3 of 3)
Video summary of main results of the article. This material relates to a paper that appeared in the May 25, 2016, issue of Science Translational Medicine, published by AAAS. The paper, by T.T. ...

Contact: Science Press Package
scipak@aaas.org
202-326-6440
American Association for the Advancement of Science

Blocking Gateway into Bone May Halt Breast Cancer Spread (2 of 3)

Blocking Gateway into Bone May Halt Breast Cancer Spread (2 of 3)
Circulating breast cancer cells after treatment with a CXCR4 inhibitor. This material relates to a paper that appeared in the May 25, 2016, issue of Science Translational Medicine, published by...

Contact: Science Press Package
scipak@aaas.org
202-326-6440
American Association for the Advancement of Science

Blocking Gateway into Bone May Halt Breast Cancer Spread (1 of 3)

Blocking Gateway into Bone May Halt Breast Cancer Spread (1 of 3)
Circulating breast cancer cells before treatment with a CXCR4 inhibitor. This material relates to a paper that appeared in the May 25, 2016, issue of Science Translational Medicine, published ...

Contact: Science Press Package
scipak@aaas.org
202-326-6440
American Association for the Advancement of Science

Rectal Cancer Images

Rectal Cancer Images
The post-chemoradiation image of rectal cancer on the left shows residual cancer that requires surgery. The image on the right shows no signs of residual cancer.

Contact: Kevin Mayhood
kevin.mayhood@case.edu
216-534-7183
Case Western Reserve University

Tumor Regression after Combined Immunotherapy

Tumor Regression after Combined Immunotherapy
CT scans show the gradual disappearance of a tumor (red arrows) after combined treatment with antitumor T cells and ipilimumab. The combined treatment began at day 300.

Contact: Ben Short
bshort@rockefeller.edu
212-327-7053
Rockefeller University Press

Deep Neural Networks

Deep Neural Networks
This image shows deep neural networks for drug discovery.

Contact: Qingsong Zhu
zhu@insilicomedicine.com
443-451-7212
InSilico Medicine, Inc.

DNA Double-Strand Breaks

DNA Double-Strand Breaks
These are DNA double-strand breaks, introduced by ionizing radiation or other mechanisms, are repaired rapidly and precisely in normal cells (right pathway). In contrast, compromised Tel1 activation ...

Contact: Saori Obayashi
saori_obayashi@mail.osaka-u.ac.jp
81-661-055-886
Osaka University

Low CAR T Cell Therapy

Low CAR T Cell Therapy
A graphic depicting the activation and inactivation of CAR T cells through a small molecule adaptor is shown. Philip S. Low, Purdue's Ralph C. Corley Distinguished Professor of Chemistry and director ...

Contact: Elizabeth Gardner
ekgardner@purdue.edu
765-494-2081
Purdue University

Breast Cells

Breast Cells
Androgen (AR, in red) and vitamin D (VDR, in green) receptors are present in the nuclei of a subset of breast cells (yellow).

Contact: Patrick Bartosch
patrick.bartosch@med.miami.edu
305-243-8219
University of Miami Miller School of Medicine

Schematic of Macrolactone 11

Schematic of Macrolactone 11
This is a schematic of macrolactone 11, currently under evaluation as a preclinical cancer drug candidate by the Rice University lab of K.C. Nicolaou. Based on the structure of the natural product and...

Contact: David Ruth
david@rice.edu
713-348-6327
Rice University

On a Path to Block Breast Cancer Relapse

On a Path to Block Breast Cancer Relapse
Even in the early stages of breast cancer, cancer cells can migrate to the bone marrow. There, they can lie dormant and cause relapse years later. Duke Health scientists have discovered ways to block ...

Contact: Samiha Khanna
samiha.khanna@duke.edu
919-419-5069
Duke University Medical Center

Rice University Researchers

Rice University Researchers
Rice University researchers have created a new way to pinpoint the location of cancer tumors using strong LED light, a unique detector and targeted nanotubes. From left: Bruce Weisman, Michael Vu, ...

Contact: David Ruth
david@rice.edu
713-348-6327
Rice University

Pinpointing the Location of Tumors

Pinpointing the Location of Tumors
A new Rice University method for medical imaging uses strong light from an LED array and an avalanche photodiode detector to pinpoint the location of tumors that have been tagged by antibody-targeted ...

Contact: David Ruth
david@rice.edu
713-348-6327
Rice University

Dr. Yi-Lin Jiang, Medical University of South Carolina

Dr. Yi-Lin Jiang, Medical University of South Carolina
Dr. Yi-Lin Jiang is on the hunt for better, more lethal therapeutics. He synthesizes novel drugs, which are the next generation of packaged drugs.

Contact: Dawn Brazell
brazell@musc.edu
843-792-3622
Medical University of South Carolina

Potato

Potato
Colorado State University researchers have developed new nutrient-rich purple potatoes.

Contact: Anne Ju Manning
anne.manning@colostate.edu
970-491-7099
Colorado State University

Ovarian Cancer Cells

Ovarian Cancer Cells
T cells (red) attack ovarian cancer cells (green).

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Researchers Describe Structure of the Nucleolus

Researchers Describe Structure of the Nucleolus
Clifford Brangwynne's research team at Princeton University has demonstrated that the nucleolus, an important cellular body, has a complex internal structure despite being made entirely of liquid. Far...

Contact: john sullivan
js29@princeton.edu
609-258-4597
Princeton University, Engineering School

Dual Nanoparticle Delivery of PL and TRAIL

Dual Nanoparticle Delivery of PL and TRAIL
Piperlongumine (PL) was encapsulated in PLGA polymer nanoparticles. TRAIL was chemically conjugated to the surface of liposomes.

Contact: Philly Lim
mllim@wspc.com.sg
65-646-65775
World Scientific

Sorting and Purification of Human Cancer Stem-Like Cells from Human Blood

Sorting and Purification of Human Cancer Stem-Like Cells from Human Blood
Sorting and purification of human cancer stem-like cells (HuSLCs) from human blood using the novel inertial microfluidic vortex sorter. (a) Photograph of the microfluidic device. (b) Microscopic ...

Contact: Philly Lim
mllim@wspc.com.sg
65-646-65775
World Scientific

T Cell Killing Tumor

T Cell Killing Tumor
Video of a cytotoxic lymphocyte killing a cancer cell. When the cancer cell is 'hit' it uptakes red dye PI and then the cancer cell undergoes apoptosis.

Contact: Ebru Yaman
ebru.yaman@wehi.edu.au
042-803-4089
Walter and Eliza Hall Institute

Human Breast Cell Lacking HOXA5

Human Breast Cell Lacking HOXA5
A human breast cell lacking HOXA5 (right) shows protruding structures similar to tumor cells, compared with a normal human breast cell (left).

Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medicine

Confocal Fluorescence Microscopy Images

Confocal Fluorescence Microscopy Images
These are confocal fluorescence microscopy images of CF2Th cancer cells incubated with LA-Si NPs.

Contact: Vladimir Koryagin
science-release@rector.msu.ru
Lomonosov Moscow State University

Biosensor LNNano

Biosensor LNNano
An inexpensive portable biosensor has been developed by researchers at Brazil's National Nanotechnology Laboratory with FAPESP's support.

Contact: Samuel Antenor
samuel@fapesp.br
55-113-838-4381
Fundação de Amparo à Pesquisa do Estado de São Paulo

Infant Undergoing Phototherapy (horizontal)

Infant Undergoing Phototherapy (horizontal)
Infant undergoing phototherapy for newborn jaundice.

Contact: Irene Sege
irene.sege@childrens.harvard.edu
617-919-3110
Dana-Farber Cancer Institute

Infant Undergoing Phototherapy (vertical)

Infant Undergoing Phototherapy (vertical)
Infant undergoing phototherapy for newborn jaundice.

Contact: Irene Sege
irene.sege@childrens.harvard.edu
617-919-3110
Dana-Farber Cancer Institute

2-DG with Fenofibrate

2-DG with Fenofibrate
Combining 2-DG with fenofibrate yields two forms of cancer cell death.

Contact: Patrick Bartosch
patrick.bartosch@med.miami.edu
305-243-8219
University of Miami Miller School of Medicine

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