IMAGE: Lung squamous cell carcinoma

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Field Test

Field Test
Millions may be exposed to private well water that tests above federal safety limits for arsenic. Here, a field test in central Maine shows one homeowner's well has a high level.

Contact: Kevin Krajick
kkrajick@ei.columbia.edu
212-854-9729
The Earth Institute at Columbia University

Arsenic Hot Spots

Arsenic Hot Spots
These are hot spots of dangerously high arsenic content (yellows to reds) can be found in many states. Greens show somewhat lower levels, but some health authorities say no level may be completely ...

Contact: Kevin Krajick
kkrajick@ei.columbia.edu
212-854-9729
The Earth Institute at Columbia University

Figure Showing Clustering of Cases in Liver-Related Cancers

Figure Showing Clustering of Cases in Liver-Related Cancers
The figure shows how the genetic landscape of HCC (in grey) and liver cancers with biliary phenotype with hepatitis (in black) are clustered, unlike those of liver cancers with biliary phenotype ...

Contact: Jens Wilkinson
jens.wilkinson@riken.jp
81-484-621-225
RIKEN

HeLa Cells

HeLa Cells
These are cultured HeLa cancer cells.

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

SIRT1 Inhibition

SIRT1 Inhibition
Above, untreated zebrafish tumor cells fluorescently labeled proliferate and migrate to other parts of the body. Below, cells treated with the SIRT1 inhibitor lose their proliferative and migration ...

Contact: Arantxa Mena
amena@idibell.cat
0034-932-607-282
IDIBELL-Bellvitge Biomedical Research Institute

CNIO Chromosomal Translocation

CNIO Chromosomal Translocation
Chromosomal translocations are possibly linked to the origin of cancer.

Contact: Nuria Noriega
comunicacion@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)

Functionalized Catanionic Vesicles for Drug and Vaccine Delivery

Functionalized Catanionic Vesicles for Drug and Vaccine Delivery
Functionalized catanionic vesicles (red) bind to and fuse with a bacterial cell surface.

Contact: Abby Robinson
abbyr@umd.edu
301-405-5845
University of Maryland

Production of Growth Factors as Public Goods Game Network

Production of Growth Factors as Public Goods Game Network
The microscopic image shows how cancer cells (colorless cells) that do not produce IGF-II but need it for their growth reproduce in a population of cancer cells that produces and consumes IGF-II (...

Contact: Reto Caluori
reto.caluori@unibas.ch
41-612-672-495
University of Basel

Cell Mechanism Discovered That May Cause Pancreatic Cancer

Cell Mechanism Discovered That May Cause Pancreatic Cancer
Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have found that defects in how cells are squeezed out of overcrowded tissue to die, a process called extrusion, may be a ...

Contact: Linda Aagard
801-587-7639
University of Utah Health Sciences

CDK6 is Crucial in Leukemia Formation

CDK6 is Crucial in Leukemia Formation
CDK6 is needed for leukemic stem cell activation (left). When CDK6 is absent, the LSC remains in a quiescent state and leukemia formation is prohibited (right).

Contact: Susanna Kautschitsch
susanna.kautschitsch@vetmeduni.ac.at
43-125-077-1153
University of Veterinary Medicine -- Vienna

Ovarian Cancer Clumps

Ovarian Cancer Clumps
Clumps of ovarian clear cell carcinoma cells formed when the two genes ARID1A and PIK3CA were mutated in mice.

Contact: Mark Derewicz
mark.derewicz@unchealth.unc.edu
919-923-0959
University of North Carolina Health Care

Ovary Comparison

Ovary Comparison
Left image shows: normal mouse ovary. Right image shows: mouse ovary with tumors after for weeks due to specific mutations in the genes ARID1A and PIK3CA.

Contact: Mark Derewicz
mark.derewicz@unchealth.unc.edu
919-923-0959
University of North Carolina Health Care

Nanodiamond

Nanodiamond
This is a schematic model showing surface and chemical structure of nanodiamond (ND) and Epirubicin (Epi), synthesis and aggregation of Epirubicin-ND complex (EPND). ND represented in truncated ...

Contact: Kimberley Wang
kimberley.wang@nus.edu.sg
National University of Singapore

How Cancer Turns Good Cells to the Dark Side

How Cancer Turns Good Cells to the Dark Side
Cancer cells have the ability to hijack the notch-signaling mechanism that cells use to communicate with each other, especially when

Contact: David Ruth
david@rice.edu
713-348-6327
Rice University

Closeup of Drug-Protein Interaction

Closeup of Drug-Protein Interaction
This is a structure of TSPO.

Contact: Karen McNulty Walsh
kmcnulty@bnl.gov
631-344-8350
DOE/Brookhaven National Laboratory

Protein Structure

Protein Structure
Left: This is a structure of TSPO (colorful).

Contact: Karen McNulty Walsh
kmcnulty@bnl.gov
631-344-8350
DOE/Brookhaven National Laboratory

Cdk1-Deficient Megakaryocytes

Cdk1-Deficient Megakaryocytes
Two Cdk1-deficient megakaryocytes extend proplatelet elongations to produce platelets.

Contact: Nuria Noriega
comunicacion@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)

Prostate Study Results

Prostate Study Results
Lead author M. Minhaj Siddiqui, M.D., assistant professor of surgery at the University of Maryland School of Medicine and director of urologic robotic surgery at the University of Maryland Marlene and...

Contact: Karen Lancaster
klancaster@umm.edu
410-328-8919
University of Maryland Medical Center

CXCR4

CXCR4
The newly solved structure of the CXCR4 receptor (black) in complex with a chemokine (purple surface). The background shows cell migration, a process driven by chemokines interacting with receptors on...

Contact: Heather Buschman
hbuschman@ucsd.edu
619-543-6163
University of California - San Diego

Electron Microscope Image of a Harmful Neutrophil

Electron Microscope Image of a Harmful Neutrophil
This is an electron microscope image of a harmful neutrophil described in the research of Dr. Zvika Granot and Dr. Zvi Fridlender.

Contact: Dov Smith
dovs@savion.huji.ac.il
972-258-82844
The Hebrew University of Jerusalem

Cancer Cells

Cancer Cells
Cancer cells in vitro form networks like the one pictured here, in which cells not only compete for space and resources, but also cooperate by sharing diffusible growth factors. Cells that do not ...

Contact: Lisa Horton
l.horton@uea.ac.uk
44-016-035-92764
University of East Anglia

Epstein-Barr Virus Erupts from Infected Immune Cell

Epstein-Barr Virus Erupts from Infected Immune Cell
An Epstein-Barr virus erupts from an infected immune cell, called a B lymphocyte.

Contact: Marc Airhart
mairhart@austin.utexas.edu
512-232-1066
University of Texas at Austin

Merkel Cell Deficiency

Merkel Cell Deficiency
After six months, whisker follicles in adult mice lacking Atoh1-expressing progenitor skin cells (left) have a deficiency of Merkel cells (green) compared with a control group (right).

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press

One Nanoparticle, 6 Types of Imaging

One Nanoparticle, 6 Types of Imaging
University at Buffalo researchers and colleagues have designed a nanoparticle detectable by six medical imaging techniques. This illustration depicts the particles as they are struck by beams of ...

Contact: Charlotte Hsu
chsu22@buffalo.edu
716-645-4655
University at Buffalo

TEM Image, Nanoparticles

TEM Image, Nanoparticles
This transmission electron microscopy image shows the nanoparticles, which consist of a core that glows blue when struck by near-infrared light, and an outer fabric of porphyrin-phospholipids (PoP) ...

Contact: Charlotte Hsu
chsu22@buffalo.edu
716-645-4655
University at Buffalo

Effect of 4-HAP

Effect of 4-HAP
Treating cells with 4-HAP causes the protein myosin II to move to the cells' periphery, making them stiffer.

Contact: Shawna Williams
shawna@jhmi.edu
410-955-8236
Johns Hopkins Medicine

Cell Division

Cell Division
This video shows the process of cell division.

Contact: Shawna Williams
shawna@jhmi.edu
410-955-8236
Johns Hopkins Medicine

Liver Cancer

Liver Cancer
The calcium influx into the liver carcinoma cell can be monitored following the exposure to citronellal (pictured in pseudo-colours).

Contact: Hanns Hatt
hanns.hatt@rub.de
49-234-322-4586
Ruhr-University Bochum

Antibodies in Action

Antibodies in Action
The figure shows human blood vessel cells (endothelial cells) grown outside the body. When endothelial cells are grown on a mixture of proteins that normally surround blood vessels, they form blood ...

Contact: Peter Kristensen
pk@eng.au.dk
45-20-36-90-97
Aarhus University

An Alternative Target for Cancer Therapy at the Ends of Chromosomes

An Alternative Target for Cancer Therapy at the Ends of Chromosomes
This movie shows that an ATR inhibitor induces numerous DNA breaks in ALT-positive cancer cells. ALT-positive U2OS osteosarcoma cells were treated with the ATR inhibitor VE-821 and analyzed by live ...

Contact: Science Press Package
scipak@aaas.org
202-326-6440
American Association for the Advancement of Science

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