IMAGE: Lung squamous cell carcinoma

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<i>Cryptococcus</i> Germination

Cryptococcus Germination
This is a spore of the deadly human fungal pathogen Cryptococcus (green) germinates into a yeast (yellow). Germination takes about 16 hours. Afterwards, the new yeast begins to reproduce by ...

Contact: Christina Hull
cmhull@wisc.edu
University of Wisconsin-Madison

DNA Damage

DNA Damage
DNA damage (red) in cells submitted to replicative stress, similar to those observed during cell reprogramming.

Contact: Nuria Noriega
comunicacion@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)

Comparison

Comparison
Lean vs. obese tissue is shown.

Contact: Melissa Osgood
mmo59@cornell.edu
607-255-2059
Cornell University

Advanced Materials

Advanced Materials
A confocal micrograph showing HCT 116 cancer cells containing drug delivery nanoparticles.

Contact: Lindsay Brooke
lindsay.brooke@nottingham.ac.uk
44-115-951-5751
University of Nottingham

Fetal Influence

Fetal Influence
Dramatic research has shown that during pregnancy, cells of the fetus often migrate through the placenta, taking up residence in many areas of the mother's body, where their influence may benefit or ...

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-258-8972
Arizona State University

Fetal Microchimerism and Maternal Health

Fetal Microchimerism and Maternal Health
This is a story about the mysteries of life. Where myth meets reality. Where science meets science fiction. Where two bodies collide and fact is stranger than fiction. We all know where babies ...

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-258-8972
Arizona State University

Comparison of Stained and Unstained Images in Breast Cancer Diagnosis

Comparison of Stained and Unstained Images in Breast Cancer Diagnosis
Figure 3 from a new article in the Journal of Biomedical Optics compares stained bright-field microscopy (top row) and SLIM (bottom row) images in their respective abilities to show malignant ...

Contact: Amy Nelson
amy@spie.org
360-685-5478
SPIE--International Society for Optics and Photonics

Salk Institute Shows How DNA Repair Proteins Distinguish DNA Breaks at Cellular and And Viral Genome

Salk Institute Shows How DNA Repair Proteins Distinguish DNA Breaks at Cellular and And Viral Genome
DNA breaks and DNA viruses are ancient and persistent threats to cellular viability. A universal difference between cellular genomes is that they are far larger and have far more proteins called ...

Contact: Salk Communications
press@salk.edu
Salk Institute

The DNA Damage Response Goes Viral: A Way in for New Cancer Treatments

The DNA Damage Response Goes Viral: A Way in for New Cancer Treatments
Salk researchers show how DNA repair proteins sound the alarm to threats, pointing to a novel cancer therapy.

Contact: Salk Communications
press@salk.edu
Salk Institute

Chin-Yo Lin and Sridevi Addanki, University of Houston

Chin-Yo Lin and Sridevi Addanki, University of Houston
Professor Chin-Yo Lin works with Ph.D. student Sridevi Addanki in his lab at the Center for Nuclear Receptors and Cell Signaling in the College of Natural Sciences and Mathematics at the University of...

Contact: Lisa Merkl
lkmerkl@uh.edu
713-743-8192
University of Houston

Cancer Cells Embedded in Cryogel

Cancer Cells Embedded in Cryogel
Cancerous melanoma cells shown with their cell bodies (green) and nuclei (blue) are nestled in tiny hollow lumens within the polymeric cryogel (red) structure.

Contact: Kat McAlpine
katherine.mcalpine@wyss.harvard.edu
617-432-8266
Wyss Institute for Biologically Inspired Engineering at Harvard

Injectable Cryogel-Based Whole-Cell Cancer Vaccines SEM

Injectable Cryogel-Based Whole-Cell Cancer Vaccines SEM
This scanning electron microscopy image shows the thawed cryogel with its well-organized interconnected porous architecture ready to be infused with cancer cells and immune factors.

Contact: Kat McAlpine
katherine.mcalpine@wyss.harvard.edu
617-432-8266
Wyss Institute for Biologically Inspired Engineering at Harvard

3-D Model of a Tumor

3-D Model of a Tumor
This is a three-dimensional model of a tumor showing cell types in varying colors.

Contact: Catriona Kelly
Catriona.Kelly@ed.ac.uk
44-131-651-4401
University of Edinburgh

A New Lens on Colorectal Cancer

A New Lens on Colorectal Cancer
New research shows the impact prostaglandin PGE2 has on the spread of CSCs to the liver. 'In cancer, the cells keep making PGE2 chronically, so it's like this wounding process that never heals. In ...

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-258-8972
Arizona State University

Compound Found in Red Wine Causes Conflicting Changes in Dogs' Immune Systems

Compound Found in Red Wine Causes Conflicting Changes in Dogs' Immune Systems
Researchers at the University of Missouri have found that resveratrol does affect the immune systems of dogs in different ways when introduced to dogs' blood.

Contact: Nathan Hurst
hurstn@missouri.edu
573-882-6217
University of Missouri-Columbia

Brd4 Distribution in Mouse Brain

Brd4 Distribution in Mouse Brain
A striking brain presence: Neurons throughout the mouse brain produce Brd4, a protein targeted by some new cancer drugs. In this cross-section of a mouse brain, Brd4-producing cells are stained red ...

Contact: Eva Kiesler
ekiesler@rockefeller.edu
212-327-7963
Rockefeller University

Protein Interaction

Protein Interaction
Nuclear magnetic resonance-derived images depict the structures of proteins Tom1 (green) and Tollip (red). These interactive regions are required for both proteins to achieve their cooperative ...

Contact: John Pastor
jdpastor@vt.edu
540-231-5646
Virginia Tech

Tumor-Suppressing Protein PTEN at Cellular Membrane

Tumor-Suppressing Protein PTEN at Cellular Membrane
An activated PTEN dimer that contains two non-mutant proteins (A) can transform the functional lipid (D) on the cellular membrane (E) into a chemical form that tunes down cancer predilection. Dimers ...

Contact: Jocelyn Duffy
jhduffy@andrew.cmu.edu
412-268-9982
Carnegie Mellon University

<em>Aplidium albicans</em>

Aplidium albicans
The ascidian Aplidium albicans was found in the Balearic Islands. The anticancer drug APLIDIN was originally found in this marine macroorganism and is now synthetically synthesized.

Contact: Carolina Pola
cpola@pharmamar.com
34-608-933-677
Pharmamar

Effects of Chemoradiation on Healthy Brain Tissue of Glioblastoma Patients

Effects of Chemoradiation on Healthy Brain Tissue of Glioblastoma Patients
MR images taken before (left) and 28 weeks after (right) the initiation of chemoradiation treatment for glioblastoma show an enlargement of the brain's ventricles, reflecting a loss of brain tissue.

Contact: Katie Marquedant
kmarquedant@partners.org
617-726-0337
Massachusetts General Hospital

Charles Fuchs on Caffeinated Coffee

Charles Fuchs on Caffeinated Coffee
Regular consumption of caffeinated coffee may help prevent the return of colon cancer after treatment and improve the chances of a cure, according to a new, large study led by Charles Fuchs, M.D., M.P...

Contact: Anne Doerr
anne_doerr@dfci.harvard.edu
617-632-4090
Dana-Farber Cancer Institute

Casanova

Casanova
In a developing Drosophila embryo, (above) E-Cadherin keep cells together to facilitate coordinated migration; (below) without E-Cad cells are disorganized.

Contact: Sònia Armengou
armengou@irbbarcelona.org
34-934-037-255
Institute for Research in Biomedicine (IRB Barcelona)

Photodynamic Cancer Therapy

Photodynamic Cancer Therapy
A new approach to cancer therapy using improved photodynamic technology has been developed at Oregon State University.

Contact: Oleh Taratula
oleh.taratula@oregonstate.edu
503-346-4704
Oregon State University

Off Target Effects

Off Target Effects
When a mouse's immune system reacts to red blood cells infected with the malaria parasite (dark spots within some of the pink cells above), changes occur in the DNA of B lymphocytes. These alterations...

Contact: Wynne Parry
wparry@rockefeller.edu
212-327-7789
Rockefeller University

Ray and the Sunbeatables™

Ray and the Sunbeatables™
Ray and the Sunbeatables™ are shown.

Contact: Scott Merville
smerville@mdanderson.org
713-792-0661
University of Texas M. D. Anderson Cancer Center

Multi-colored Metastasis

Multi-colored Metastasis
This is a multi-colored metastasis in the peritoneal lining of the abdomen comprised of red and yellow fluorescent cells demonstrating that pancreatic cancer spreads through interactions between ...

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

With New Contrast Agent, MRI Detects Micrometastases in Mice

With New Contrast Agent, MRI Detects Micrometastases in Mice
For earlier detection of metastases, Case Western Reserve University researchers developed a magnetic resonance imaging contrast agent that includes a probe that binds to fibrin-fibronectin complexes ...

Contact: Kevin Mayhood
kevin.mayhood@case.edu
216-534-7183
Case Western Reserve University

Fashioning Cancer: Glioma

Fashioning Cancer: Glioma
Normal brain area on the left (blue and green) is encountering invading cancer cells (glioma; red). Credit: Wun Chey Sin/Christian Naus. Cells in Community dress: Bronwyn Malloy, UBC Alumna & now ...

Contact: Heather Amos
heather.amos@ubc.ca
604-822-3213
University of British Columbia

Intrahepatic Cholestasis of Pregnancy Linked with Liver Cancer

Intrahepatic Cholestasis of Pregnancy Linked with Liver Cancer
In a new study researchers at the University of Gothenburg found that the risk of hepatobiliary cancer and immune-mediated and cardiovascular diseases later in life is higher in women with ...

Contact: Hanns-Ulrich Marschall
hanns-ulrich.marschall@gu.se
University of Gothenburg

MRI Detects Early Breast Cancer Metastases in Mice

MRI Detects Early Breast Cancer Metastases in Mice
Metastasis occurs when cells are shed from primary breast cancer tumor and establish a new tumor at a distant site. For early detection of the metastasis with MRI, the Lu Lab at Case Western ...

Contact: Raymond A MacDougall
macdougallr@mail.nih.gov
301-496-3500
NIH/National Institute of Biomedical Imaging & Bioengineering

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