IMAGE: Lung squamous cell carcinoma

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Meditation Reduces Stress During Biopsy

Meditation Reduces Stress During Biopsy
Meditation reduces stress during biopsy.

Contact: Sarah Avery
sarah.avery@duke.edu
919-660-1306
Duke University Medical Center

MicroRNA (miR-34a)

MicroRNA (miR-34a)
Duke scientists grew two sets of cellular "miniguts" on culture dishes and stimulated them with inflammatory factors. The miniguts on the left are normal. But on the right, the deletion of a...

Contact: Ken Kingery
ken.kingery@duke.edu
919-660-8414
Duke University

Neural Crest Cells

Neural Crest Cells
The image shows induced human neural crest cells. Human embryonic stem cells display neural crest characteristic expression after only five days of culture under WNT induction. Transcription factors ...

Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside

Antibody Targets Multiple Sites to Outsmart Drug-Resistant Colorectal Cancer (1 of 1)

Antibody Targets Multiple Sites to Outsmart Drug-Resistant Colorectal Cancer (1 of 1)
Antibodies that block epidermal growth factor receptor (EGFR), a surface receptor that drives cancer growth, are effective against colorectal cancer, but many patients develop resistance. Researchers ...

Contact: Science Press Package
scipak@aaas.org
202-326-6440
American Association for the Advancement of Science

Modifying Hepatitis E Virus-like Particles to Target Cancer Cells

Modifying Hepatitis E Virus-like Particles to Target Cancer Cells
Hepatitis E virus capsids can resist passing through the digestive system. These virus-like particles could be used to carry vaccines or drugs into the body through the oral route. By modifying the ...

Contact: Andy Fell
ahfell@ucdavis.edu
530-752-4533
University of California - Davis

Cystine RCC

Cystine RCC
The majority of kidney cell carcinomas are missing the VHL tumor-suppressor gene. Duke researchers showed that these renal cancer cells remain healthy when all nutrients are present (left panel), but ...

Contact: Karl Bates
karl.bates@duke.edu
919-681-8054
Duke University

Section of a Head and Neck Cancer Biopsy

Section of a Head and Neck Cancer Biopsy
Section of a head and neck cancer biopsy was stained for p21 (brown) and for S6 phosphorylation (red). S6 phosphorylation depends directly on mTOR and, therefore, its detection is an indication of ...

Contact: Vanessa Pombo
comunicacion@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)

Common Signature Found in Tumor DNA 5 Types of Cancer

Common Signature Found in Tumor DNA 5 Types of Cancer
The signature results from a chemical modification of DNA called methylation, which can control the expression of genes like a dimmer on a light switch. They hope this finding will spur development of...

Contact: Jeannine Mjoseth
Mjosethj@mail.nih.gov
301-402-0911
NIH/National Human Genome Research Institute

Epigenetic Enzyme Inhibition

Epigenetic Enzyme Inhibition
Human breast cancers (blue) grown on mice show marked reductions in inflammatory cytokines such as IL1a and IL6 (yellow) when MLL1 is inhibited.

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Peptide cp28

Peptide cp28
The compound Cp28 (orange) binds to the EGF protein (green), a target in cancer. This interaction prevents EGF from binding to its receptor EGFR.

Contact: Sònia Armengou
armengou@irbbarcelona.org
34-934-037-255
Institute for Research in Biomedicine (IRB Barcelona)

Gene- Fusion Mutation

Gene- Fusion Mutation
Three-Way mechanism drives pediatric low-grade gliomas.

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Chinnaiyan Lab

Chinnaiyan Lab
Arul Chinnaiyan, right, consults with one of his lab associates.

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Autophagy Deregulation

Autophagy Deregulation
This image shows the implication of autophagy deregulation in Parkinson's disease (PD).

Contact: Hayley London
hayley.london@tgac.ac.uk
01-603-450-107
The Genome Analysis Centre

Autophagy

Autophagy
TGAC's Autophagy Regulatory Network resource provides an integrated and systems-level source for autophagy ('biological self-destruction') research in humans, features in the recent "Guidelines ...

Contact: Hayley London
hayley.london@tgac.ac.uk
01-603-450-107
The Genome Analysis Centre

Height Influences Risk of Major Non-Communicable Diseases

Height Influences Risk of Major Non-Communicable Diseases
This infographic shoes that tall people have a lower risk for cardiovascular disease and type 2 diabetes, but a higher risk of cancer due to dietary and interacting factors such as genetics and stress...

Contact: Dr. Astrid Glaser
glaser@dzd-ev.de
Deutsches Zentrum fuer Diabetesforschung DZD

Brain Tumor Vascularisation

Brain Tumor Vascularisation
Brain tumor vascularisation is visualized using T2*-weighted magnetic resonance imaging.

Contact: Emily Packer
e.packer@elifesciences.org
01-223-855-373
eLife

Brain Tumor Microvessels

Brain Tumor Microvessels
Brain tumor microvessels are visualized using dual-color ultramicroscopy.

Contact: Emily Packer
e.packer@elifesciences.org
01-223-855-373
eLife

<I>Escherichia coli</I>

Escherichia coli
Research on the effect of the enzyme APOBEC3G on DNA replication was conducted in the bacteria Escherichia coli.

Contact: Kevin D. Fryling
kfryling@iu.edu
812-856-2988
Indiana University

Accumulation of dihydroceramides after ABC294640 administration

Accumulation of dihydroceramides after ABC294640 administration
The signal for ABC294640 is detected only when the drug but not the vehicle was administered (upper panel). The intensity for two different dihydroceramides is shown in the middle panel (dhC16-cer) ...

Contact: Heather Woolwine
woolwinh@musc.edu
843-792-7669
Medical University of South Carolina

Leukemia Cells

Leukemia Cells
Leukemia cells (yellow) are shown dispersed among fat cells (red) and surrounded by supportive cells (blue).

Contact: Ellin Kavanagh
ekavanagh@chla.usc.edu
323-361-8505
Children's Hospital Los Angeles

Zebrafish Eggs

Zebrafish Eggs
On the far right, a zebrafish embryo breaks free from a group of unhatched sibling eggs.

Contact: Elaine Schmidt
eschmidt@mednet.ucla.edu
310-794-2272
University of California - Los Angeles Health Sciences

A Breast Cancer Metastasis in the Lungs

A Breast Cancer Metastasis in the Lungs
A metastasis now growing in lung tissue (blue) that originated from at least two cells (red and green) from a multicolored tumor in the mammary gland of a mouse.

Contact: Catherine Gara
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine

Aster Formation

Aster Formation
Asters form as motor protein draws the minus ends of the purple microtubules together.

Contact: Leah Burrows
lburrows@seas.harvard.edu
617-495-1351
Harvard John A. Paulson School of Engineering and Applied Sciences

Spontaneous Contraction of Microtubules

Spontaneous Contraction of Microtubules
The microtubules organize into networks that spontaneously contract.

Contact: Leah Burrows
lburrows@seas.harvard.edu
617-495-1351
Harvard John A. Paulson School of Engineering and Applied Sciences

Epigenomic Communication System

Epigenomic Communication System
The epigenomic communication system of embryonic stem cells can be explored interactively on the following website: http://epistemnet.bioinfo.cnio.es.

Contact: Vanessa Pombo
comunicacion@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)

DNA Methylation Heatmap

DNA Methylation Heatmap
A DNA methylation gene marker panel was designed to identify three distinctive IDHmutant groups. Shown here is a heatmap, where samples with a high amount of methylation appear in red, and those with ...

Contact: Karin Eskenazi
ket2116@columbia.edu
212-342-0508
Columbia University Medical Center

Special Issue: New Insights on Obesity and Anti-Obesity Therapy (1 of 2)

Special Issue: New Insights on Obesity and Anti-Obesity Therapy (1 of 2)
This is a schematic of possible maternal influences on cancer risk in offspring. In a maternal obesogenic environment, offspring cells could inherit malfunctioning mitochondria and/or deregulated ...

Contact: Science Press Package
scipak@aaas.org
202-326-6440
American Association for the Advancement of Science

Reach and Reel In

Reach and Reel In
Cancerous cells "recruit" cells into tumors by extending a bridge of sorts and reeling in both healthy and cancerous cells. The UI researchers documented the phenomenon for the first time in...

Contact: Richard Lewis
richard-c-lewis@uiowa.edu
319-384-0012
University of Iowa

Cellular Health

Cellular Health
Researchers at the University of Iowa tracked in real time the movement of individual, healthy cells and cancerous breast tissue cells. This video shows that healthy breast tissue cells remain ...

Contact: Richard Lewis
richard-c-lewis@uiowa.edu
319-384-0012
University of Iowa

Evil Envoys

Evil Envoys
Researchers at the University of Iowa tracked in real time the movement of individual cancerous breast tissue cells. The video shows how the cancerous cells extend and probe for other cells, then reel...

Contact: Richard Lewis
richard-c-lewis@uiowa.edu
319-384-0012
University of Iowa

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