IMAGE: Lung squamous cell carcinoma

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How Cells Avoid Aneuploidy

How Cells Avoid Aneuploidy
Inhibiting AAK activity leads to defects in error correction and chromosomes (blue) being pinned near spindle poles because the kinetochores (red) near the poles fail to let go of spindle microtubules...

Contact: Janet Lathrop
jlathrop@admin.umass.edu
413-545-0444
University of Massachusetts at Amherst

Dr. Martha Goetsch, Oregon Health & Science University

Dr. Martha Goetsch, Oregon Health & Science University
Martha Goetsch, M.D., M.P.H., is an adjunct assistant professor in the Oregon Health & Science University Department of Obstetrics and Gynecology.

Contact: Ariane Le Chevallier
holma@ohsu.edu
503-494-8231
Oregon Health & Science University

Stimulated Raman Scattering Imaging of Glucose Uptake Activity

Stimulated Raman Scattering Imaging of Glucose Uptake Activity
Stimulated Raman scattering (SRS) imaging of glucose uptake activity by targeting the alkyne tag of a novel glucose analogue in live mouse brain hippocampal neurons and tumor tissues (in red).

Contact: Wei Min
wm2256@columbia.edu
212-851-9433
Columbia University

Acute Myeloid Leukemia

Acute Myeloid Leukemia
Photo shows cells from acute myeloid leukemia.

Contact: Bonnie Ward
bjward@ucsd.edu
619-543-6163
University of California - San Diego

TOPLESS

TOPLESS
The tetrameric TOPLESS complex with the EAR motif peptides bound at its repressor-peptide binding grooves. The repressor peptides are shown as a ball presentation.

Contact: Beth Hinshaw Hall
Beth.HinshawHall@vai.org
616-234-5519
Van Andel Research Institute

MAGI

MAGI
Brown University computer scientists have developed a new interactive tool to help researchers and clinicians explore the genetic underpinnings of cancer. The tool -- dubbed MAGI, for Mutation ...

Contact: Kevin Stacey
kevin_stacey@brown.edu
401-863-3766
Brown University

<em>Aplidium albicans</em>

Aplidium albicans
The marine anticancer compound APLIDIN was obtained from the tunicate Aplidium albicans, which is found in the Balearic Islands.

Contact: Carolina Pola
cpola@pharmamar.com
34-608-933-677
Pharmamar

Are We Getting Good Value from High-Priced Drugs?

Are We Getting Good Value from High-Priced Drugs?
ICER: Providing independent analysis on drug pricing linked to patient benefit. Visit www.icer-review.org.

Contact: Jemma Weymouth
jweymouth@burness.com
301-280-5706
Burness Communications

Lymph Flow

Lymph Flow
Lymph flow drives development of lymphatic valves in collecting lymphatic vessels in the embryonic mouse mesentery. Two transcription factors: PROX1 (green) and FOXC2 (red) are highly unregulated in ...

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Karawinna

Karawinna
This is Karawinna, a one-year old devil taken at Cradle Mountain.

Contact: Glenn Harris
G.Harris@soton.ac.uk
44-023-805-93212
University of Southampton

Hanhah Siddle Lab

Hanhah Siddle Lab
This is Dr Hannah Siddle.

Contact: Glenn Harris
G.Harris@soton.ac.uk
44-023-805-93212
University of Southampton

Hannah Siddle

Hannah Siddle
This is Dr Hannah Siddle.

Contact: Glenn Harris
G.Harris@soton.ac.uk
44-023-805-93212
University of Southampton

Cancer Therapy

Cancer Therapy
A new delivery system for protective polyphenols like resveratrol may have value in cancer chemotherapy.

Contact: Adam Alani
adam.alani@oregonstate.edu
503-346-4702
Oregon State University

Accessory Proteins and Metephase Chromosomes

Accessory Proteins and Metephase Chromosomes
A) Shelterin recruits accessory proteins to the telomeres that facilitate the complex process of telomere copying and maintenance associated with cell multiplication. B) Representative images of ...

Contact: Nuria Noriega
comunicacion@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)

Making customized T Cells

Making customized T Cells
This is a graphic showing a process for producing large numbers of activated, customized T cells using magnetic nanoparticles and a column.

Contact: Shawna Williams
shawna@jhmi.edu
410-955-8236
Johns Hopkins Medicine

Cell Uptake

Cell Uptake
The cells in this image have turned fluorescent pink, showing that the new drug delivery system results in high cellular uptake after being irradiated by near infrared light.

Contact: Ken Kingery
ken.kingery@duke.edu
919-660-8414
Duke University

TEM Nanoparticles

TEM Nanoparticles
This image, taken using a transmission electron microscope, shows: (A) a bare nanoparticle, (B) a nanoparticle prepared for coating and (C) a nanoparticle coated with a thin layer of drug-delivering ...

Contact: Ken Kingery
ken.kingery@duke.edu
919-660-8414
Duke University

Mesh

Mesh
A 3-D view of the mesh: microtubules (green tubes) of the mitotic spindle are held together by a yellow network, the mesh.

Contact: Nicola Jones
N.Jones.1@warwick.ac.uk
44-247-615-0868
University of Warwick

X-Ray Photoemission Spectroscopy Unlocks Graphene's Cancer-Treating Potential

X-Ray Photoemission Spectroscopy Unlocks Graphene's Cancer-Treating Potential
Elise Ramleth Østli and Ph.D. candidate Federico Mazzola of the Norwegian University of Science and Technology (NTNU) check their experiment. As part of her master's project at NTNU, Elise ...

Contact: Justin Wells
justin.wells@ntnu.no
47-735-93428
Norwegian University of Science and Technology

Neutrophils Induce Bleeding

Neutrophils Induce Bleeding
These time-lapse images of inflamed tissue in mice reveal that bleeding (red arrowheads) occurs exactly at the sites where neutrophils traverse the blood vessel wall (white arrowheads).

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press

Research Links Intrahepatic Cholestasis of Pregnancy with  Liver Cancer and Other Diseases Later in Life

Research Links Intrahepatic Cholestasis of Pregnancy with Liver Cancer and Other Diseases Later in Life
ICP is associated with hepatobiliary diseases that might predispose to cancer and also with gestational diabetes and preeclampsia. Women with ICP have increased risk of later hepatobiliary cancer and ...

Contact: Sybrand Boer Iwema
hmsmedia@elsevier.com
31-204-852-781
Elsevier Health Sciences

Jagged Ligands

Jagged Ligands
New research at Rice University shows how tumors create chaos in the development of neighboring blood vessels, causing them to grow too quickly and not form properly. The notch signaling pathway that ...

Contact: David Ruth
david@rice.edu
713-348-6327
Rice University

Mitotic Spindle Apparatus

Mitotic Spindle Apparatus
Mitotic spindle apparatus preparing for chromosome segregation: an unaligned chromosome activates the checkpoint (green) and thereby prevents premature segregation.

Contact: Olivia Poisson
olivia.poisson@unibas.ch
University of Basel

Microfabricated Device

Microfabricated Device
A microfabricated device developed by the Massachusetts General Hospital Center for Engineering in Medicine is able to analyze the effects of pro-drugs -- substances transformed within the liver into ...

Contact: Philly Lim
mllim@wspc.com.sg
65-646-65775
World Scientific

Glioblastoma

Glioblastoma
Non-tumorigenic glioblastoma cells (left) can spontaneously acquire cancer stem cell characteristics (right).

Contact: Heather Buschman
hbuschman@ucsd.edu
619-543-6163
University of California - San Diego

<I>Conus episcopatus</I>

Conus episcopatus
This is a Conus episcopatus snail.

Contact: Gemma Ward
g.ward1@uq.edu.au
61-733-462-155
University of Queensland

Photostatin Added to Human Cancer Cell Line

Photostatin Added to Human Cancer Cell Line

Video shows a single cell from a human cancer cell line which is fluorescently labeled on the growing tips of its microtubules, revealing where these microtubules are being built up. At the ...

Contact: Joseph Caputo
jcaputo@cell.com
617-335-6270
Cell Press

Photostatin Exposure Comparison

Photostatin Exposure Comparison
This photo shows incubated human cancer cell lines in cell culture, treated with our photostatin. Note the contrast in cell fate for those kept in the dark (left) versus those exposed to brief pulses ...

Contact: Joseph Caputo
jcaputo@cell.com
617-335-6270
Cell Press

Trifunctional Antibody

Trifunctional Antibody
This image shows a trifunctional antibody.

Contact: Dr. Ralph Mocikat
Mocikat@helmholtz-muenchen.de
49-893-187-1302
Helmholtz Zentrum München - German Research Center for Environmental Health

Media Overall Survival for Patients with Stage 4 Colorectal Cancer

Media Overall Survival for Patients with Stage 4 Colorectal Cancer
A Duke Medicine study found that that thinner Stage 4 colorectal cancer patients lived an average of two-and-a-half months less than obese patients.

Contact: Samiha Khanna
samiha.khanna@duke.edu
919-419-5069
Duke University Medical Center

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