IMAGE: Lung squamous cell carcinoma

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Fibroblasts

Fibroblasts
Left hand side: untreated fibroblasts. Center: inflammatory stimulation hardly affects cell morphology. Right hand side: stimulation of wound healing activity results in proliferation and higher cell ...

Contact: Christopher Gerner
christopher.gerner@univie.ac.at
43-142-775-2302
University of Vienna

Extracting RNA From a Single Cell

Extracting RNA From a Single Cell
Researchers use a small pipette (right) to extract and analyze the RNA of individual breast cancer cells to track a cancer cell line's evolution.

Contact: Salk Communications
press@salk.edu
Salk Institute

Cancer Evolution

Cancer Evolution
In this video, a Salk researcher explains how cancer evolves to become drug resistant.

Contact: Salk Communications
press@salk.edu
Salk Institute

PECAM1-positive Tumor

PECAM1-positive Tumor
This is an intensity-colored image of blood flow in a PECAM1-positive tumor.

Contact: Mark Derewicz
mark.derewicz@unch.unc.edu
919-923-0959
University of North Carolina Health Care

Endocrine Cells

Endocrine Cells
Endocrine cells develop in human islet-like structures following transplantation in an animal model. These cells produce insulin in response to glucose, effectively replacing the insulin that is lost ...

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Thyroid Cancer (3 of 3)

Thyroid Cancer (3 of 3)
This is a tall cell type papillary thyroid carcinoma.

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Thyroid Cancer (1 of 3)

Thyroid Cancer (1 of 3)
This is a classical type papillary thyroid carcinoma.

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Thyroid Cancer (2 of 3)

Thyroid Cancer (2 of 3)
This is a classical type C thyroid carcinoma.

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Cytokinetic Defect and Apoptosis of T4Cytokinetic Defect and Apop7D Cells Caused by OTS964 Treatment

Cytokinetic Defect and Apoptosis of T4Cytokinetic Defect and Apop7D Cells Caused by OTS964 Treatment
This video shows treatment with OTS964 induced cytokinetic defect with inter-cellular bridges that eventually led to cell apoptosis. Cell pictures were taken every 10 min.

Contact: John Easton
john.easton@uchospitals.edu
773-795-5225
University of Chicago Medical Center

OTS964 in Action

OTS964 in Action
This is an illustration depicting liposomal OTS964 entering cancer cells where it blocks the enzyme TOPK, preventing the final stage of cell division.

Contact: John Easton
john.easton@uchospitals.edu
773-795-5225
University of Chicago Medical Center

Initial UV Excitation

Initial UV Excitation
This is the initial UV excitation leading to photofragmentation.

Contact: Jason Socrates Bardi
jbardi@aip.org
240-535-4954
American Institute of Physics

Can Scientists Custom Grow Organs?

Can Scientists Custom Grow Organs?
Michael Helmrath, M.D., M.S., surgical director of the Intestinal Rehabilitation Program at Cincinnati Children's Hospital Medical Center, talks about researchers successfully growing human intestinal...

Contact: Nick Miller
nicholas.miller@cchmc.org
513-803-6035
Cincinnati Children's Hospital Medical Center

Simulated Tumor Growth

Simulated Tumor Growth
Here are snapshots of a simulated noninvasive tumor growing in the extracellular matrix.

Contact: Tien Nguyen
tienn@princeton.edu
Princeton University

Some Rice-Based Foods for People with Celiac Disease Contain Relevant Amounts of Arsenic

Some Rice-Based Foods for People with Celiac Disease Contain Relevant Amounts of Arsenic
The arsenic content is high in some rice-based products for people with celiac disease.

Contact: SINC
info@agenciasinc.es
34-914-251-820
FECYT - Spanish Foundation for Science and Technology

Ebola Particle

Ebola Particle
A study shows mortality from diseases with skin manifestation, including Ebola, is hundreds of times higher in developing countries than in developed countries.

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Nano Medicine

Nano Medicine
The nanomedicine (red) with the optimal size shows the highest tumor tissue (blue) retention integrated over time, which is the collective outcome of deep tumor tissue penetration, efficient cancer ...

Contact: Jianjun Cheng
jianjunc@illinois.edu
217-244-3924
University of Illinois College of Engineering

Helicase Structures

Helicase Structures
This image shows averaged electron microscope images of two intermediate helicase structures. The top shows an ORC binding the two ring structures together, and the bottom shows the completed double-...

Contact: Justin Eure
jeure@bnl.gov
631-344-2347
DOE/Brookhaven National Laboratory

3-D Model

3-D Model
This image shows a 3-D model based on electron microscopy data of the double-ring structure loaded onto a DNA helix.

Contact: Justin Eure
jeure@bnl.gov
631-344-2347
DOE/Brookhaven National Laboratory

Fruit Fly Border Cells (1 of 2)

Fruit Fly Border Cells (1 of 2)
Fruit fly border cells form clusters of six to eight cells, which display directional migration during oogenesis. The egg chamber is in red and border cells (their actin cytoskeletons) are in green. ...

Contact: Minna Poukkula
minna.poukkula@helsinki.fi
University of Helsinki

Fruit Fly Border Cells (2 of 2)

Fruit Fly Border Cells (2 of 2)
Fruit fly border cells form clusters of six to eight cells, which display directional migration during oogenesis. Migration of border cells in egg chambers can be examined in detail by live-cell ...

Contact: Minna Poukkula
minna.poukkula@helsinki.fi
University of Helsinki

Saving Khloe's Eyes

Saving Khloe's Eyes
Some children with advanced retinoblastoma are not good candidates for conventional intraocular ophthalmic infusion therapy -- too often making removal of the eye the only viable treatment for saving ...

Contact: Nick Miller
nicholas.miller@cchmc.org
513-803-6035
Cincinnati Children's Hospital Medical Center

Normal Gene vs. Mutated Gene

Normal Gene vs. Mutated Gene
Here is a normal PTEN gene (top) as compared to a mutated PTEN gene (bottom), where the mutated gene will lose directional ability and its "false foot" (light blue) will force it to walk to different ...

Contact: Brittany Borghi
brittany-borghi@uiowa.edu
319-384-0048
University of Iowa

Mutated Gene vs. Healthy Gene

Mutated Gene vs. Healthy Gene
This is a normal PTEN gene (top) as compared to a mutated PTEN gene (bottom), where the mutated gene will lose directional ability and its "false foot" (light blue) will force it to walk to different ...

Contact: Brittany Borghi
brittany-borghi@uiowa.edu
319-384-0048
University of Iowa

DNA-Based Drug Delivery System

DNA-Based Drug Delivery System
Biomedical engineering researchers have developed a drug delivery system consisting of nanoscale "cocoons" made of DNA that target cancer cells and trick the cells into absorbing the cocoon. Enzymes ...

Contact: Matt Shipman
matt_shipman@ncsu.edu
919-515-6386
North Carolina State University

Neural Stem Cells on the <i>Drosophila</i> Brain

Neural Stem Cells on the Drosophila Brain
This image shows neural stem cells on the Drosophila brain.

Contact: Andrew Gould
andrew.gould@plymouth.ac.uk
University of Plymouth

Sonic Hedgehog Protein Causes DNA Damage

Sonic Hedgehog Protein Causes DNA Damage
Scientists at the IRCM and the University of Montreal discovered a mechanism that promotes the progression of medulloblastoma, the most common brain tumour found in children. The team, led by Frederic...

Contact: William Raillant-Clark
w.raillant-clark@umontreal.ca
514-343-7593
University of Montreal

Loss of STAT3 Changes a NK Cell's Function

Loss of STAT3 Changes a NK Cell's Function
Loss of STAT3 makes NK cells more efficient in recognizing and destroying melanoma cells. Additionally, the excretion of enzymes that fight leukemia cells is increased.

Contact: Susanna Kautschitsch
susanna.kautschitsch@vetmeduni.ac.at
43-125-077-1153
University of Veterinary Medicine -- Vienna

Chronic Skin Inflammation Linked to Cancer

Chronic Skin Inflammation Linked to Cancer
Activated immune cells, shown in red and green, cluster at the site of an allergic skin rash. Scientists have learned that this inflammation can promote skin tumor formation if it persists.

Contact: Michael C. Purdy
purdym@wustl.edu
314-286-0122
Washington University School of Medicine

II-Beta Form of Protein Kinase A

II-Beta Form of Protein Kinase A
With a background of scattered neutrons, this image shows a model of the II-beta form of PKA. A neutron beam used for imaging (behind gray circle) helped researchers identify a region of II-beta that ...

Contact: Phil Sahm
phil.sahm@hsc.utah.edu
801-581-2517
University of Utah Health Sciences

Inner Membrane

Inner Membrane
The inner membrane of each mitochondrion contains distinctive folds known as cristae. In a normal mitochondrion (left) these folds fill the interior, but these folds are lost in damaged or ...

Contact: Barbara K. Kennedy
science@psu.edu
814-863-4682
Penn State

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