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Halloysite-Doped Biocomposite Scaffolds

Halloysite-Doped Biocomposite Scaffolds
A sketch demonstrating the fabrication and in vitro and in vivo testing of novel halloysite-doped biopolymer tissue engineering scaffold

Contact: Yevgeniya Litvinova
press@kpfu.ru
7-843-233-7345
Kazan Federal University

Professor Jack Cuzick and the IBIS-II Team

Professor Jack Cuzick and the IBIS-II Team
This is a photograph of Professor Jack Cuzick and the IBIS-II team.

Contact: Joel Winston
j.winston@qmul.ac.uk
44-207-882-7943
Queen Mary University of London

Making Precision Medicine a Reality: Genomics Researchers Find Road Map (2 of 2)

Making Precision Medicine a Reality: Genomics Researchers Find Road Map (2 of 2)
Understanding the genetic and biologic basis of diseases like rheumatoid arthritis, cancer, diabetes and Alzheimer's will lead to new therapies.

Contact: Jean Spinelli
jspinell@email.arizona.edu
520-626-2531
University of Arizona Health Sciences

Repair of DNA Breaks

Repair of DNA Breaks
LINP1 enhances the repair of DNA breaks by serving as a scaffold that links two other proteins in the repair machinery.

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Tumor After Anti-angiogenic Therapy

Tumor After Anti-angiogenic Therapy
Following anti-angiogenic therapy, tumors develop regions containing no blood vessels (green) and therefore no oxygen (red). The tumor cells are made visible by dyeing the nuclei blue.

Contact: Yannik Sprecher
yannik.sprecher@unibas.ch
41-612-672-424
University of Basel

Could a Cancer Drug Be Repurposed for Fragile X Syndrome?

Could a Cancer Drug Be Repurposed for Fragile X Syndrome?
Schematic diagram showing the stages of neurogenesis in the adult dentate gyrus of the hippocampus and cell lineage-specific markers. qNSC, quiescent NSC; aNSC, activated NSC. This material relates to...

Contact: Science Press Package
scipak@aaas.org
202-326-6440
American Association for the Advancement of Science

Breast Cancer Cells in 3-D Culture

Breast Cancer Cells in 3-D Culture
Detail of breast cancer cells in 3-D culture, collectively invading into the surrounding extracellular matrix.

Contact: Dr. Christina Scheel
christina.scheel@helmholtz-muenchen.de
49-893-187-2012
Helmholtz Zentrum München - German Research Center for Environmental Health

Image of the NuRD Complex

Image of the NuRD Complex
This is an image of the NuRD complex.

Contact: Professor John Schwabe
john.schwabe@le.ac.uk
01-162-297-030
University of Leicester

Microscopic Images of a Mouse Retina

Microscopic Images of a Mouse Retina
On the left the new blood vessels are in branching mode; on the right they are increasing in diameter under the influence of the VEGFA hormone. The cell membrane is colored green, the cell nuclei blue...

Contact: Vera Glaßer
vera.glasser@mdc-berlin.de
49-309-406-2120
Max Delbrück Center for Molecular Medicine in the Helmholtz Association

Comments from Lead Researcher on New ALL Relapse Revention Protocols

Comments from Lead Researcher on New ALL Relapse Revention Protocols
William L. Carroll, M.D., from NYU Langone Medical Center and its Perlmutter Cancer Center discusses the findings from a Journal of Clinical Oncology study showing new protocols to improve relapse ...

Contact: Jim Mandler
jim.mandler@nyumc.org
212-404-3525
NYU Langone Medical Center / New York University School of Medicine

Dr. Haidong Zhu and Dr. Yanbhin Dong, Augusta University

Dr. Haidong Zhu and Dr. Yanbhin Dong, Augusta University
(Left) Dr. Haidong Zhu, molecular geneticist at the Georgia Prevention Institute at the Medical College of Georgia at Augusta University and corresponding author of the study & Dr. Yanbin Dong, ...

Contact: Toni Baker
tbaker@augusta.edu
706-721-4421
Medical College of Georgia at Augusta University

An image of the HDAC Enzyme

An image of the HDAC Enzyme
This is an image of the HDAC enzyme.

Contact: Professor John Schwabe
js336@leicester.ac.uk
01-162-297-030
University of Leicester

Human PDAC Tumors Showing Expressions

Human PDAC Tumors Showing Expressions
Human PDAC tumors shows co-expression of CXCL1 (red) and CK19 (green; a marker of PADC) by confocal microscopy.

Contact: Jim Mandler
jim.mandler@nyumc.org
212-404-3525
NYU Langone Medical Center / New York University School of Medicine

The GS-DProSw Molecule in Its Inactive Form Can Be Activated By Visible Light

The GS-DProSw Molecule in Its Inactive Form Can Be Activated By Visible Light
The GS-DProSw molecule in its inactive form (blue) can be activated by visible light (red) and "switched off" again by UV light.

Contact: Monika Landgraf
presse@kit.edu
49-721-608-47414
Karlsruher Institut für Technologie (KIT)

Microbial Therapy Develop to Fight Cancer

Microbial Therapy Develop to Fight Cancer
Evelo Biosciences has licensed a cancer therapy developed in the laboratory of University of Chicago researcher Thomas Gajewski that employs select gut microbes to boost the immune system's attack on ...

Contact: Steve Koppes
skoppes@uchicago.edu
773-702-8366
University of Chicago

Brain Tumor Stem Cell

Brain Tumor Stem Cell
This is an image of brain tumor stem cell taken by Dr. Takrima Haque in the laboratory of Dr. Arezu Jahani-Asl.

Contact: Amelia Buchanan
ambuchanan@ohri.ca
61-379-855-557-3687
Ottawa Hospital Research Institute

Caveolin-1

Caveolin-1
The "gatekeeper" caveolin-1 (purple-colored in the picture) makes its way to the surface of a stressed cell, and prevents endocytosis, that is, it prevents most proteins from entering the ...

Contact: Cecilia Schubert
cecilia.schubert@kommunikation.lu.se
46-073-062-3858
Lund University

Mattias Belting Produced this Video Illustration

Mattias Belting Produced this Video Illustration
Video illustrates how some of the proteins that are on the surface of a stressed cell and illuminated first reside on the cell's surface and then gradually enters the cell.

Contact: Cecilia Schubert
cecilia.schubert@kommunikation.lu.se
46-073-062-3858
Lund University

Brain Stem Cells

Brain Stem Cells
Neural stem cells (red) interact with their niche glial cells (green) to remain in quiescence.

Contact: Dr. Christian Berger
bergerc@uni-mainz.de
49-613-139-24328
Johannes Gutenberg Universitaet Mainz

PLK4 Induced Aster Formation

PLK4 Induced Aster Formation
PLK4 induced aster formation around centrioles.

Contact: Vanessa Borges
vborges@igc.gulbenkian.pt
Instituto Gulbenkian de Ciencia

Pancreatic Mouse Model

Pancreatic Mouse Model
A form of immunotherapy shows promise against pancreatic cancer in a mouse model. The scientists engineered T cells to recognize pancreatic cancer cells -- the cells homed to mice's tumors within a ...

Contact: Rhonda Curry
rcurry@fredhutch.org
206-240-6011
Fred Hutchinson Cancer Research Center

Pembrolizumab Image

Pembrolizumab Image
Multispectral immunofluorescence shows the interface between Merkel cell tumor cells (orange) and host immune cells (yellow marks CD8+ lymphocytes, red marks CD68+ macrophages). Cell-surface PD-L1 ...

Contact: Rhonda Curry
rcurry@fredhutch.org
206-240-6011
Fred Hutchinson Cancer Research Center

Cancer Cell Sliding Behavior

Cancer Cell Sliding Behavior
This video shows a breast cancer cell sliding past another cell.

Contact: Joseph Caputo
jcaputo@cell.com
617-397-2802
Cell Press

Cancer Cell Reversing Direction

Cancer Cell Reversing Direction
This video shows a breast cancer cell reversing direction.

Contact: Joseph Caputo
jcaputo@cell.com
617-397-2802
Cell Press

REVEALER

REVEALER
To better characterize the functional context of genomic variations in cancer, researchers developed a new computer algorithm called REVEALER.

Contact: Heather Buschman
hbuschman@ucsd.edu
619-543-6163
University of California - San Diego

Cellular Trojan Horse Yields Potential Cancer Treatment

Cellular Trojan Horse Yields Potential Cancer Treatment
Confocal microscopy image of stem cells loaded with drug containing polymeric microparticles.

Contact: Haley Bridger
hbridger@partners.org
617-525-6383
Brigham and Women's Hospital

Merkel Cell Tumor Cells

Merkel Cell Tumor Cells
Multispectral immunofluorescence shows the interface between Merkel cell tumor cells (orange) and host immune cells (yellow marks CD8+ lymphocytes, red marks CD68+ macrophages). Cell-surface PD-L1 ...

Contact: Vanessa Wasta
wasta@jhmi.edu
410-736-1397
Johns Hopkins Medicine

Ohio State Shows that SPF30 Sunscreen Can Reduce Melanoma

Ohio State Shows that SPF30 Sunscreen Can Reduce Melanoma
In a first of its kind study, researchers at The Ohio State University Comprehensive Cancer Center in Columbus, Ohio prove that sunscreens with an SPF-30 rating can prevent the formation of melanoma, ...

Contact: Amanda Harper
amanda.harper2@osumc.edu
614-685-5420
Ohio State University Wexner Medical Center

SPF30 Sunscreens Delay Melanoma Incidence in Preclinical Model

SPF30 Sunscreens Delay Melanoma Incidence in Preclinical Model
Application of sun protection factor 30 (SPF30) sunscreen prior to exposure to ultraviolet-B (UVB) light delayed melanoma onset in a mouse model of the disease, according to data from a team at The ...

Contact: Amanda Harper
amanda.harper2@osumc.edu
614-685-5420
Ohio State University Wexner Medical Center

Melanoma Survivor Kelly Haldeman

Melanoma Survivor Kelly Haldeman
Kelly Haldeman, of Bucyrus, Ohio, is diligent about using sunscreen after she was diagnosed with stage 3 melanoma at the age of 20.

Contact: Amanda Harper
amanda.harper2@osumc.edu
614-685-5420
Ohio State University Wexner Medical Center

CTC Cluster Unfolds to Pass Through Capillary-Sized Constriction

CTC Cluster Unfolds to Pass Through Capillary-Sized Constriction
Cells within a prostate cancer circulating tumor cell cluster unfold to pass through a capillary-sized constriction in a single-file chain.

Contact: Noah Brown
nbrown9@partners.org
617-643-3907
Massachusetts General Hospital

Clearing the Air

Clearing the Air
This microscopic image shows tissues from an adult mouse lung in which the FOXF1 gene has been deleted in endothelial cells for two weeks. The lungs undergo thickening of tiny air sacs called ...

Contact: Nick Miller
nicholas.miller@cchmc.org
513-803-6035
Cincinnati Children's Hospital Medical Center

Retinoblastoma Tumor Cells

Retinoblastoma Tumor Cells
This is a picture of retinoblastoma tumor cells.

Contact: Debra Kain
dkain@chla.usc.edu
323-361-7628
Children's Hospital Los Angeles

Implantable Device Targets Pancreatic Cancer

Implantable Device Targets Pancreatic Cancer
Researchers engineered a flexible polymer film that is made from a polymer called PLGA. The film can be rolled into a narrow tube and inserted through a catheter. Once the film reaches the pancreas, ...

Contact: Sarah McDonnell
s_mcd@mit.edu
617-253-8923
Massachusetts Institute of Technology

Flexible Polymer Film

Flexible Polymer Film
Researchers engineered a flexible polymer film that is made from a polymer called PLGA. The film can be rolled into a narrow tube and inserted through a catheter. Once the film reaches the pancreas, ...

Contact: Sarah McDonnell
s_mcd@mit.edu
617-253-8923
Massachusetts Institute of Technology

The Study's Key Findings

The Study's Key Findings
This table summarizes the findings of a phase III clinical trial showing that radiation therapy plus combination chemotherapy is better than radiation therapy alone for patients with low-grade gliomas...

Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Wexner Medical Center

Sandra Rieger, Ph.D., MDI Biological Laboratory

Sandra Rieger, Ph.D., MDI Biological Laboratory
Recent research by Sandra Rieger, Ph.D., of the MDI Biological Laboratory identifying the underlying mechanisms of peripheral neuropathy, or nerve damage, has raised the prospect that drug therapies ...

Contact: Stefanie Matteson
smatteso@mdibl.org
207-288-9880
Mount Desert Island Biological Laboratory

HPV Coverage Map

HPV Coverage Map
This map shows full-series HPV coverage among adolescents varies substantially across states.

Contact: Ziba Kashef
ziba.kashef@yale.edu
203-436-9317
Yale University

One Step Closer to a Targeted Therapy for Deadliest Breast Cancer

One Step Closer to a Targeted Therapy for Deadliest Breast Cancer
Triple-negative breast cancer (TNBC) is the most lethal form of breast cancer, and the only type of breast tumor still lacking a targeted treatment. New research pinpoints a JAK2-specific inhibitor as...

Contact: Science Press Package
scipak@aaas.org
202-326-6440
American Association for the Advancement of Science

Chemo Boosts HPV Vaccine's Efficacy Against Cervical Cancer

Chemo Boosts HPV Vaccine's Efficacy Against Cervical Cancer
A human papillomavirus (HPV) vaccine and chemotherapy may offer an effective combination strategy against advanced cervical cancer, results from a small clinical trial and study in mice show. This ...

Contact: Science Press Package
scipak@aaas.org
202-326-6440
American Association for the Advancement of Science

Antioxidants in Antidiabetic Drugs May Fuel Cancer Spread, Mouse Study Shows

Antioxidants in Antidiabetic Drugs May Fuel Cancer Spread, Mouse Study Shows
Antioxidants are commonly used to treat patients with diabetes, a disease driven by oxidative stress. A new study in mice suggests that some antioxidant-containing diabetes medications may fuel cancer...

Contact: Science Press Package
scipak@aaas.org
202-326-6440
American Association for the Advancement of Science

High Expression of COMP in Breast Cancer Cells

High Expression of COMP in Breast Cancer Cells
High expression of COMP in breast cancer cells, seen here in brown, is associated with poor clinical prognosis for the patient. Cancer cells expressing COMP become more invasive and change their ...

Contact: Cecilia Schubert
cecilia.schubert@kommunikation.lu.se
46-073-062-3858
Lund University

New Method to Preserve Microfluidic Devices for HIV Monitoring in Developing Countries

New Method to Preserve Microfluidic Devices for HIV Monitoring in Developing Countries
Researchers employed a lensless imaging method to rapidly count CD4 T cells using CMOS (complementary metal-oxide semiconductor) sensor - the same imaging sensor found in cell phone cameras. The ...

Contact: Gisele Galoustian
ggaloust@fau.edu
561-297-2676
Florida Atlantic University

Researchers Develop New Method to Preserve Microfluidic Devices for HIV Monitoring in Developing Countries

Researchers Develop New Method to Preserve Microfluidic Devices for HIV Monitoring in Developing Countries
Researchers used trehalose, a form of sugar that is present in some plants and animals, to preserve the microfluidic device. They packaged and vacuum sealed the trelahose treated device in plastic and...

Contact: Gisele Galoustian
ggaloust@fau.edu
561-297-2676
Florida Atlantic University

DNA Mutations

DNA Mutations
Median DNA mutations from 1,161 tumors across 14 cancer types analyzed by UNSW Australia scientists.

Contact: Dan Wheelahan
d.wheelahan@unsw.edu.au
61-435-930-465
University of New South Wales

Snakes and Ladders

Snakes and Ladders
Workers representing the repair system known as nucleotide excision repair (NER), repairing DNA and snakes, representing proteins that bind DNA at gene promoters, potentially preventing them from ...

Contact: Dan Wheelahan
d.wheelahan@unsw.edu.au
61-435-930-465
University of New South Wales

Dr. Jason Wong, University of New South Wales

Dr. Jason Wong, University of New South Wales
Lead author of the study Dr. Jason Wong, group leader of Bioinformatics and Integrative Genomics at UNSW's Lowy Cancer Research Centre.

Contact: Dan Wheelahan
d.wheelahan@unsw.edu.au
61-435-930-465
University of New South Wales

Retina

Retina
This is a stem cell-derived retina.

Contact: Debra Kain
DKain@chla.usc.edu
323-361-1812
Children's Hospital Los Angeles

Red-capped Manakin

Red-capped Manakin
This is an adult male red-capped manakin, which produces wing claps by rapidly retracting its wings toward its body.

Contact: Emily Packer
e.packer@elifesciences.org
eLife

'Superfast' Courtship Display

'Superfast' Courtship Display
This is a high-speed video of a golden-collared manakin performing a roll-snap.

Contact: Emily Packer
e.packer@elifesciences.org
eLife

Kaplan-Meier Curves

Kaplan-Meier Curves
This is a picture of Kaplan-Meier curves for overall survival, by lung cancer status.

Contact: Robert J. Chen
rjcc@ntu.edu.tw
Pensoft Publishers

Tumor Penetration

Tumor Penetration
This unique drug delivery strategy involves the decoration of nanovehicles with enzymes known to break down hyaluronic acid.

Contact: Britt Faulstick
bef29@drexel.edu
215-895-2617
Drexel University

Healthy Breast Tissue

Healthy Breast Tissue
In healthy breast tissue, the percentage of cells expressing molecular marker Ki67 (green) and p27 (red) was low.

Contact: BD Colen
bd_colen@harvard.edu
617-495-7821
Harvard Medical School

ATR Inhibitors -- Chemotherapy

ATR Inhibitors -- Chemotherapy
Cell treated with ATR inhibitors were developed at the CNIO. The treatment generates breaks in the DNA of cells. Each green dot indicates the presence of a break. Chromosomes are stained in blue.

Contact: Nuria Noriega
comunicacion@cnio.es
Centro Nacional de Investigaciones Oncológicas (CNIO)

Prostate Cancer Drug Unexpectedly Thwarts Immunotherapy

Prostate Cancer Drug Unexpectedly Thwarts Immunotherapy
Androgen deprivation therapy (ADT) is a mainstay of prostate cancer treatment. New research suggests that some forms of ADT can suppress immune responses against prostate cancer, suggesting that ...

Contact: Science Press Package
scipak@aaas.org
202-326-6440
American Association for the Advancement of Science

The Mevalonate Pathway Activates Arf6

The Mevalonate Pathway Activates Arf6
Thanks to the activity of the mevalonate pathway, Rab11b delivers Arf6 (green) to the plasma membrane, where it can be activated to promote cancer cell invasion and drug resistance.

Contact: Ben Short
bshort@rockefeller.edu
212-327-7053
Rockefeller University Press

Advancing Health Research through Canada's Fastest Supercomputer

Advancing Health Research through Canada's Fastest Supercomputer
This is an IBM Blue Gene/Q supercomputer.

Contact: Ross Neitz
rneitz@ualberta.ca
780-492-5986
University of Alberta Faculty of Medicine & Dentistry

Liver Cell Nucleosome

Liver Cell Nucleosome
Schematic of opening of nucleosome in liver cell, with linker histone ejected, accessible nucleosomes with pioneer factors, and liver-specific transcription factors.

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Self-Stabilizing Magnetic Colloid

Self-Stabilizing Magnetic Colloid
Self-stabilizing magnetic colloid.

Contact: Dmitry Malkov
dvmalkov@corp.ifmo.ru
895-337-75508
ITMO University

<em>Scutellaria</em> Root

Scutellaria Root
Root specific flavones (RSFs) from Scutellaria have a variety of reported additional beneficial effects including anti-oxidant and anti-viral properties.

Contact: Geraldine Platten
geraldine.platten@jic.ac.uk
01-603-450-238
John Innes Centre

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