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Low CAR T Cell Therapy

Low CAR T Cell Therapy
A graphic depicting the activation and inactivation of CAR T cells through a small molecule adaptor is shown. Philip S. Low, Purdue's Ralph C. Corley Distinguished Professor of Chemistry and director ...

Contact: Elizabeth Gardner
ekgardner@purdue.edu
765-494-2081
Purdue University

Breast Cells

Breast Cells
Androgen (AR, in red) and vitamin D (VDR, in green) receptors are present in the nuclei of a subset of breast cells (yellow).

Contact: Patrick Bartosch
patrick.bartosch@med.miami.edu
305-243-8219
University of Miami Miller School of Medicine

Schematic of Macrolactone 11

Schematic of Macrolactone 11
This is a schematic of macrolactone 11, currently under evaluation as a preclinical cancer drug candidate by the Rice University lab of K.C. Nicolaou. Based on the structure of the natural product and...

Contact: David Ruth
david@rice.edu
713-348-6327
Rice University

Matthew Davids, Dana-Farber Cancer Institute

Matthew Davids, Dana-Farber Cancer Institute
This is Matthew Davids, MD, MMSc.

Contact: Teresa M Herbert
teresa_herbert@dfci.harvard.edu
617-632-5653
Dana-Farber Cancer Institute

Rice University Researchers

Rice University Researchers
Rice University researchers have created a new way to pinpoint the location of cancer tumors using strong LED light, a unique detector and targeted nanotubes. From left: Bruce Weisman, Michael Vu, ...

Contact: David Ruth
david@rice.edu
713-348-6327
Rice University

Pinpointing the Location of Tumors

Pinpointing the Location of Tumors
A new Rice University method for medical imaging uses strong light from an LED array and an avalanche photodiode detector to pinpoint the location of tumors that have been tagged by antibody-targeted ...

Contact: David Ruth
david@rice.edu
713-348-6327
Rice University

Dr. Yi-Lin Jiang

Dr. Yi-Lin Jiang
Dr. Yi-Lin Jiang is on the hunt for better, more lethal therapeutics. He synthesizes novel drugs, which are the next generation of packaged drugs.

Contact: Dawn Brazell
brazell@musc.edu
843-792-3622
Medical University of South Carolina

Potato

Potato
Colorado State University researchers have developed new nutrient-rich purple potatoes.

Contact: Anne Ju Manning
anne.manning@colostate.edu
970-491-7099
Colorado State University

Ovarian

Ovarian
T cells (red) attack ovarian cancer cells (green).

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Researchers Describe Structure of the Nucleolus

Researchers Describe Structure of the Nucleolus
Clifford Brangwynne's research team at Princeton University has demonstrated that the nucleolus, an important cellular body, has a complex internal structure despite being made entirely of liquid. Far...

Contact: john sullivan
js29@princeton.edu
609-258-4597
Princeton University, Engineering School

Dual Nanoparticle Delivery of PL and TRAIL

Dual Nanoparticle Delivery of PL and TRAIL
Piperlongumine (PL) was encapsulated in PLGA polymer nanoparticles. TRAIL was chemically conjugated to the surface of liposomes.

Contact: Philly Lim
mllim@wspc.com.sg
65-646-65775
World Scientific

Sorting and Purification of Human Cancer Stem-Like Cells from Human Blood

Sorting and Purification of Human Cancer Stem-Like Cells from Human Blood
Sorting and purification of human cancer stem-like cells (HuSLCs) from human blood using the novel inertial microfluidic vortex sorter. (a) Photograph of the microfluidic device. (b) Microscopic ...

Contact: Philly Lim
mllim@wspc.com.sg
65-646-65775
World Scientific

T Cell Killing Tumor

T Cell Killing Tumor
Video of a cytotoxic lymphocyte killing a cancer cell. When the cancer cell is 'hit' it uptakes red dye PI and then the cancer cell undergoes apoptosis.

Contact: Ebru Yaman
ebru.yaman@wehi.edu.au
042-803-4089
Walter and Eliza Hall Institute

Human Breast Cell Lacking HOXA5

Human Breast Cell Lacking HOXA5
A human breast cell lacking HOXA5 (right) shows protruding structures similar to tumor cells, compared with a normal human breast cell (left).

Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medicine

Confocal Fluorescence Microscopy Images

Confocal Fluorescence Microscopy Images
These are confocal fluorescence microscopy images of CF2Th cancer cells incubated with LA-Si NPs.

Contact: Vladimir Koryagin
science-release@rector.msu.ru
Lomonosov Moscow State University

Biosensor LNNano

Biosensor LNNano
An inexpensive portable biosensor has been developed by researchers at Brazil's National Nanotechnology Laboratory with FAPESP's support.

Contact: Samuel Antenor
samuel@fapesp.br
55-113-838-4381
Fundação de Amparo à Pesquisa do Estado de São Paulo

Infant Undergoing Phototherapy (horizontal)

Infant Undergoing Phototherapy (horizontal)
Infant undergoing phototherapy for newborn jaundice.

Contact: Irene Sege
irene.sege@childrens.harvard.edu
617-919-3110
Dana-Farber Cancer Institute

Infant Undergoing Phototherapy (vertical)

Infant Undergoing Phototherapy (vertical)
Infant undergoing phototherapy for newborn jaundice.

Contact: Irene Sege
irene.sege@childrens.harvard.edu
617-919-3110
Dana-Farber Cancer Institute

2-DG with Fenofibrate

2-DG with Fenofibrate
Combining 2-DG with fenofibrate yields two forms of cancer cell death.

Contact: Patrick Bartosch
patrick.bartosch@med.miami.edu
305-243-8219
University of Miami Miller School of Medicine

Spread Stopped

Spread Stopped
All four mouse lungs had been exposed to cancer, but the two on the left were left untreated while the two on the right received an intervention that spurred one particular protein pathway to keep ...

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University

Heart Failure Survival Rates for Patients With and Without Sarcopenia

Heart Failure Survival Rates for Patients With and Without Sarcopenia
The heart failure survival rate is lower over a 750-day period for patients who have sarcopenia vs those who do not.

Contact: J. Sanderson, N. Fukuda
research-coordinator@jimu.kumamoto-u.ac.jp
Kumamoto University

Brain Natriuretic Peptide (BNP) Levels vs. Patients With and Without Sarcopenia

Brain Natriuretic Peptide (BNP) Levels vs. Patients With and Without Sarcopenia
The risk of heart failure is higher in patients with sarcopenia vs those who don't.

Contact: J. Sanderson, N. Fukuda
research-coordinator@jimu.kumamoto-u.ac.jp
Kumamoto University

Rapalink, A New Generation mTOR Inhibitor

Rapalink, A New Generation mTOR Inhibitor
The Rapalink compound uses a unique strategy to block mTOR, a molecule that helps drive the growth of many tumors.

Contact: Jim Keeley
keeleyj@hhmi.org
301-215-8858
Howard Hughes Medical Institute

Colonic Crypt

Colonic Crypt
Balance between the two isoforms, P1 and P2, of nuclear receptor HNF4-alpha in the colonic crypt influences susceptibility to colitis and colon cancer. P1 is seen here in green. P2 is seen in red.

Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside

Immunofluorescent Stained Mouse Intestine

Immunofluorescent Stained Mouse Intestine
Immunofluorescent staining of intestinal epithelium tissue shows cell growth (green). In a normal mouse model (left), cell growth is controlled but in a mouse model with the ERK1/2 pathway blocked (...

Contact: Yadira Galindo
ygalindo@ucsd.edu
619-543-6163
University of California - San Diego

Cancer Cells After Treatment

Cancer Cells After Treatment
After treatment: The breast cancer treatment downregulates FLT3. The cancer cells die.

Contact: Iris Uras
iris.uras@vetmeduni.ac.at
43-699-182-04603
University of Veterinary Medicine -- Vienna

Cancer Cells Before Treatment

Cancer Cells Before Treatment
This is a photograph of cancer cells before treatment.

Contact: Iris Uras
iris.uras@vetmeduni.ac.at
43-699-182-04603
University of Veterinary Medicine -- Vienna

Leukemia Therapy

Leukemia Therapy
Childhood cancer: targeted therapy of resistant leukemia cells.

Contact: Beat Bornhauser
beat.bornhauser@kispi.uzh.ch
41-446-348-817
University of Zurich

DNA Damage in Mouse Ovary Treated with Cisplatin

DNA Damage in Mouse Ovary Treated with Cisplatin
A section of mouse ovary treated with cisplatin (chemotherapy drug) for 24 hours. Red staining labels oocytes, green staining marks DNA damage and blue shows nuclei of all cells.

Contact: Joyce Peterson
joyce.peterson@jax.org
207-288-6058
Jackson Laboratory

Breast Cancer Cells Use mTOR Signaling to Recruit Suppressor Cells to Promote Tumor Growth

Breast Cancer Cells Use mTOR Signaling to Recruit Suppressor Cells to Promote Tumor Growth
The mTOR pathway, an important pathway controlling cell growth and metabolism, is aberrantly activated in some breast tumors. This activation leads to increased expression of granulocytic colony ...

Contact: Dana Benson
benson@bcm.edu
713-798-4710
Baylor College of Medicine

Immunostaining

Immunostaining
In pancreatic cancer cells, loss of IGF2BP3 reduced cell invasiveness and other factors associated with tumor progression and metastasis. In these images, immunostaining of control and IGF2BP3-...

Contact: Tim Stephens
stephens@ucsc.edu
831-459-4352
University of California - Santa Cruz

Book Cover

Book Cover
Image shows the book cover.

Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside

Novel insight into Interaction Between Discharge Plasma and Cells via TRP Channel

Novel insight into Interaction Between Discharge Plasma and Cells via TRP Channel
Short-lived reactive species generated by the plasma enhance the calcium influx through the TRP channels.

Contact: Toshiro Kaneko
kaneko@ecei.tohoku.ac.jp
Tohoku University

MSK Surgeons Present Strategies for Increasing Survival in Soft Tissue Sarcoma Patients With Lung Metastases Undergoing Resection

MSK Surgeons Present Strategies for Increasing Survival in Soft Tissue Sarcoma Patients With Lung Metastases Undergoing Resection
Overall survival from first pulmonary metastasectomy.

Contact: Nicole Baritot
press@aats.org
978-299-4520
American Association for Thoracic Surgery

Stuck Dividing

Stuck Dividing
In some cancers, including chondroblastoma and a rare form of childhood sarcoma, a mutation in histone H3 reduces global levels of methylation (dark areas) in tumor cells but not in normal cells (...

Contact: Katherine Fenz
kfenz@rockefeller.edu
212-327-7913
Rockefeller University

Out-FOXing Prostate Cancer

Out-FOXing Prostate Cancer
FOXF1 staining in normal prostate epithelium and prostate tumors. Images are magnified at ×200 (×400, inset); scale bars, 50 μm. This material relates to a paper that appeared in the ...

Contact: Science Press Package
scipak@aaas.org
202-326-6440
American Association for the Advancement of Science

Bone Cancer Cells

Bone Cancer Cells
Cells from a bone cancer caused by a histone mutation are brown if they contain the mutation (left). Purple cells are intact, without the mutation (right).

Contact: Peter W. Lewis
plewis@discovery.wisc.edu
608-316-4388
University of Wisconsin-Madison

MRI

MRI
Radiation dose is delivered by beams directed from many angles combined with implanted seeds (white spots). By integrating the two types of radiation, the highest dose is delivered only within the ...

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Dr. Piyush Sindhu Sharma in the IPC PAS Laboratory

Dr. Piyush Sindhu Sharma in the IPC PAS Laboratory
A special polymer film, developed at the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw, recognizes molecules of neopterin. The film is a key element of future cancer ...

Contact: Wlodzimierz Kutner
wkutner@ichf.edu.pl
48-223-433-217
Institute of Physical Chemistry of the Polish Academy of Sciences

A Special Polymer Film Rrecognizes Molecules of Neopterin

A Special Polymer Film Rrecognizes Molecules of Neopterin
A special polymer film, developed at the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw, recognizes molecules of neopterin. The film is a key element of future cancer ...

Contact: Wlodzimierz Kutner
wkutner@ichf.edu.pl
48-223-433-217
Institute of Physical Chemistry of the Polish Academy of Sciences

Dr. Koichi Kobayashi in His Lab

Dr. Koichi Kobayashi in His Lab
Dr. Koichi Kobayashi, pictured here in his lab at the Texas A&M Health Science Center College of Medicine, found that the gene NLRC5 is a novel biomarker for cancer patient survival and ...

Contact: Holly Shive
hshive@tamhsc.edu
979-436-0613
Texas A&M University

Gamma-Retroviruses Preferentially Integrate near Cancer-Associated Genes

Gamma-Retroviruses Preferentially Integrate near Cancer-Associated Genes
This is a gene comparison in multiple cell types. A: Venn diagram showing the level of overlap between the top 100 gene targets in each cell line tested. B: As (A) but considering overlap of the ...

Contact: Beth Jones
bjones@plos.org
PLOS

Time-Lapse Imaging of Control Cells

Time-Lapse Imaging of Control Cells
Metastatic breast cancer cells placed on a dish and monitored with time-lapse microscopy were active, constantly moving around the dish.

Contact: John Easton
john.easton@uchospitals.edu
773-795-5225
University of Chicago Medical Center

Time-Lapse Video of Cancer Cells Lacking Autophagy-Related Genes

Time-Lapse Video of Cancer Cells Lacking Autophagy-Related Genes
Cancer cells lacking autophagy-related genes didn't move at all. They tried to move, to put out new protrusions, to migrate, but they appeared to be stuck.

Contact: John Easton
john.easton@uchospitals.edu
773-795-5225
University of Chicago Medical Center

Ga-68 DOTATATE PET/CT v. In-111-DTPA-octreotide scan

Ga-68 DOTATATE PET/CT v. In-111-DTPA-octreotide scan
In-111-DTPA-octreotide scan (A) demonstrates recurrent mesenteric nodule (arrow) on the anterior view in a patient with a mid-gut carcinoid tumor resected 5 years previously, with no other tumor seen ...

Contact: Laurie Callahan
lcallahan@snmmi.org
Society of Nuclear Medicine

Arnosti

Arnosti
A new study from Michigan State University makes inroads in learning to 'read' the genome, a key goal of modern biology.

Contact: Layne Cameron
layne.cameron@cabs.msu.edu
517-353-8819
Michigan State University

Human Glioblastoma Cells

Human Glioblastoma Cells
Brain tumors in dogs are strikingly similar to their human tumor counterparts. In a recent study in the journal PLOS Genetics, researchers at Uppsala University and Swedish University of ...

Contact: Karin Forsberg Nilsson
karin.nilsson@igp.uu.se
46-701-679-579
Uppsala University

DNA

DNA
By cutting DNA in the nucleus of a cancer cell, the enzyme MUS81 triggers an immune attack against the cancer cell.

Contact: Khor Ing Wei
medkiw@nus.edu.sg
65-677-26983
National University of Singapore

The Mechanical Forces of T Cells

The Mechanical Forces of T Cells
A 3-D rendering of a fluorescence image maps the piconewton forces applied by T cells. The height and color indicates the magnitude of the applied force.

Contact: Carol Clark
carol.clark@emory.edu
404-727-0501
Emory Health Sciences

Chromosome Separation

Chromosome Separation
When the kinetochore-attached microtubules are from opposite sides of the cell and are pulling in opposite direction they generate tension that causes a protein molecule, Stu2, to stabilize the ...

Contact: Michael McCarthy
leilag@uw.edu
206-685-0381
University of Washington Health Sciences/UW Medicine

Adrenal

Adrenal
This is a photograph of adrenal cancer.

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

One Critical Gene in Green Algae Responsible for Multicellular Evolution

One Critical Gene in Green Algae Responsible for Multicellular Evolution
A gene found in this eight-celled green algae is responsible for the evolution of multicellular organisms.

Contact: Brad Olson
bjsco@k-state.edu
785-532-6149
Kansas State University

Multiple Myeloma

Multiple Myeloma
Multiple myeloma cells in the bone marrow.

Contact: Patrick Bartosch
patrick.bartosch@med.miami.edu
305-243-8219
University of Miami Miller School of Medicine

Glioblastoma Density Map

Glioblastoma Density Map
Glioblastoma density maps reveal that glioblastoma tend to occur in proximity to the subventricular zone.

Contact: Jackie Carr
jcarr@ucsd.edu
619-543-6163
University of California - San Diego

Giant Beam Zaps Tumor Cells

Giant Beam Zaps Tumor Cells
The new proton therapy center at UF Health Cancer Center - Orlando Health took four years to build and is treating as many as 20 patients a day for the 15 minute treatment. On average, patients ...

Contact: Drew Schaar
drew@mediasourcetv.com
614-932-9950
MediaSource

Enormous Machine Beams Protons into Tiny Tumor Cells

Enormous Machine Beams Protons into Tiny Tumor Cells
A person is diagnosed with a brain? Or spinal cord tumor about every six minutes in the US for many, the tumors are inoperable because they grow too close to critical parts of the body. But remarkable...

Contact: Drew Schaar
drew@mediasourcetv.com
614-932-9950
MediaSource

Proton Therapy Saves Critical Areas of Body

Proton Therapy Saves Critical Areas of Body
Proton beam therapy, newly available at UF Health Cancer Center - Orlando Health, is the most precise form of radiation treatment that works by releasing energy precisely at the location of the tumor ...

Contact: Drew Schaar
drew@mediasourcetv.com
614-932-9950
MediaSource

Boxer

Boxer
Boxers are the dog-breed with the highest risk of developing glioma.

Contact: Amy Yau
ayau@plos.org
44-012-234-42823
PLOS

Molecular Mayhem

Molecular Mayhem
In this microscopic image, brain cells from adult mice are shown expressing the protein Olig2 (shown in red). Researchers at Cincinnati Children's Hospital Medical Center report May 9 in Cancer ...

Contact: Nick Miller
nicholas.miller@cchmc.org
513-803-6035
Cincinnati Children's Hospital Medical Center

Controlling Cholesterol Metabolism in Pancreatic Cancer

Controlling Cholesterol Metabolism in Pancreatic Cancer
Researchers have shown how controlling cholesterol metabolism in pancreatic cancer cells reduces metastasis to other organs, pointing to a potential new treatment. Findings showed a higher number of ...

Contact: emil venere
venere@purdue.edu
765-494-4709
Purdue University

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