IMAGE: Lung squamous cell carcinoma

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The Virtual Breast

The Virtual Breast
A 'virtual breast' image, part of a software program designed by Michigan Tech's Jingfeng Jiang. The software is designed to train health professionals how to read ultrasound elastography images used ...

Contact: Jennifer Donovan
jbdonova@mtu.edu
906-487-4521
Michigan Technological University

Pink Bollworm

Pink Bollworm
The pink bollworm, a foe of cotton, has evolved resistance to genetically modified cotton in India but not in Arizona, where farmers have planted refuges of conventional cotton to reduce selection for...

Contact: Daniel Stolte
stolte@email.arizona.edu
520-626-4402
University of Arizona

Bt Cotton Field in Arizona

Bt Cotton Field in Arizona
This is a field planted with Bt cotton in Southern Arizona.

Contact: Daniel Stolte
stolte@email.arizona.edu
520-626-4402
University of Arizona

Blue Fluorescence

Blue Fluorescence
The new strategy activates the EGFR inhibitor specifically under hypoxic conditions (indicated by blue fluorescence).

Contact: Christian Kowol
christian.kowol@univie.ac.at
0043-142-775-2609
University of Vienna

Prodrug Concept

Prodrug Concept
This is a schematic illustration of the used prodrug concept: The compound is inactive under normoxia, while hypoxia of the malignant tissue induces release of the active drug.

Contact: Christian Kowol
christian.kowol@univie.ac.at
0043-142-775-2609
University of Vienna

ALT Telomeres Fish for Homology

ALT Telomeres Fish for Homology
The perpetual proliferation of cancer cells requires a means to maintain telomere length. Alternative lengthening of telomeres (ALT) is a poorly understood mechanism of telomere maintenance that is ...

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Bacteria Molecule Kills Cancer Cells

Bacteria Molecule Kills Cancer Cells
Cancer cells on the left are pre-molecule treatment. The cells on the right are after the treatment and are dead.

Contact: Nathan Hurst
hurstn@missouri.edu
573-882-6217
University of Missouri-Columbia

Key Factor Maintains Stem Cell Identify

Key Factor Maintains Stem Cell Identify
Following inhibition of a key protein, these embryonic stem cells underwent differentiation and lost their pluripotency, the ability to become any cell type. (Nuclei are in green and nuclei expressing...

Contact: Jim Mandler
Jim.Mandler@nyumc.org
212-404-3525
NYU Langone Medical Center / New York University School of Medicine

West Highland Terrier

West Highland Terrier
This is an image of a West Highland terrier.

Contact: Professor Alexander Gorban
ag153@le.ac.uk
01-162-231-433
University of Leicester

New Chip

New Chip
This illustration shows the design of a new chip capable of simulating a tumor's 'microenvironment' to test the effectiveness of nanoparticles and drugs that target cancer. The new system, called a ...

Contact: Emil Venere
venere@purdue.edu
765-494-4709
Purdue University

The Crystal Structure of TIPE3

The Crystal Structure of TIPE3
This is a cartoon presentation of TH-domain of human TIPE3 (residues 21-204). Helices are shown in green, and the two connected phosphoinositide-shaped tubes of 2Fo-Fc electron density are shown in ...

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Stanford Researchers Develop Protein Therapy to Stop Metastasis

Stanford Researchers Develop Protein Therapy to Stop Metastasis
Early but promising tests in lab mice suggest that a bioengineered 'decoy' protein, administered intravenously, can halt the spread of cancer from the original tumor site. Years of subsequent tests ...

Contact: Tm Abate
tabate@stanford.edu
650-736-2245
Stanford School of Engineering

Graphene Biosensor

Graphene Biosensor
This is an illustration of an epitaxial graphene channel biosensor for detection of targeted 8-hydroxydeoxyguanosine (8-OHdG) biomarker. (A) Schematic of MLEG device (B) Thin film of covalently ...

Contact: Michael Bishop
michael.bishop@iop.org
01-179-301-032
Institute of Physics

Pancreatic Tumor Environment

Pancreatic Tumor Environment
In the pancreatic tumor microenvironment, non-cancerous stromal cells (blue) impede the delivery and efficacy of chemotherapy.

Contact: Salk Communications
press@salk.edu
Salk Institute

Modified Vitamin D Shows Promise as Treatment for Pancreatic Cancer

Modified Vitamin D Shows Promise as Treatment for Pancreatic Cancer
Salk scientists find that a vitamin D-derivative makes tumors vulnerable to chemotherapy.

Contact: Salk Communications
press@salk.edu
Salk Institute

Overview of MRI-Compatible Prostate Biopsy Robot

Overview of MRI-Compatible Prostate Biopsy Robot
This is an overview of the MRI-compatible prostate biopsy robotic system developed by researchers at Worcester Polytechnic Institute (WPI), Johns Hopkins University, and Brigham and Women's Hospital. ...

Contact: Michael Cohen
mcohen@wpi.edu
508-868-4778
Worcester Polytechnic Institute

Professional Recommendations Against Routine Prostate Cancer Screening Have Little Effect

Professional Recommendations Against Routine Prostate Cancer Screening Have Little Effect
The effect of guidelines recommending that elderly men should not be routinely screened for prostate cancer 'has been minimal at best,' according to a new study led by researchers at Henry Ford ...

Contact: Dwight Angell
dwight.angell@hfhs.org
313-876-8709
Henry Ford Health System

Fruit Fly Eyes

Fruit Fly Eyes
Michigan State University scientists look at fruit fly eyes to unlock the secrets of an important cancer gene.

Contact: Layne Cameron
layne.cameron@cabs.msu.edu
517-353-8819
Michigan State University

Neoepitope Distinctions

Neoepitope Distinctions
This simulation shows structural differences between mutant (yellow) and normal (orange) immune targets called neoepitopes. Researchers reveal how evaluating these distinctions can help pinpoint ...

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press

Wistar Leads SPORE Grant in Melanoma

Wistar Leads SPORE Grant in Melanoma
Wistar's Meenhard Herlyn, D.V.M., D.Sc., is the primary investigator of a $12.1 National Cancer Institute SPORE -- Specialized Project of Research Excellence -- grant in collaboration with researchers...

Contact: Greg Lester
glester@wistar.org
215-898-3943
The Wistar Institute

Chokeberry

Chokeberry
These are chokeberries (Aronia melanocarpa).

Contact: Becky Attwood
r.attwood@soton.ac.uk
University of Southampton

Proteins

Proteins
Researchers from Erlangen can identify individual unlabeled proteins by the weak shadow that the biomolecules produce when they scatter light. For their biosensor, the scientists use a very sensitive ...

Contact: Vahid Sandoghdar
vahid.sandoghdar@mpl.mpg.de
49-091-316-877-200
Max-Planck-Gesellschaft

Disease Associations

Disease Associations
University of Pennsylvania researchers identified several miRNA mutations that were associated with particular ethnic groups and had links to cancer and other diseases.

Contact: Katherine Unger Baillie
kbaillie@upenn.edu
215-898-9194
University of Pennsylvania

Cancer Cells

Cancer Cells
This approach will take biological data and develop models to try to answer basic questions about cancer that can possibly help find a cure.

Contact: Ivy F. Kupec
ikupec@nsf.gov
703-292-8796
National Science Foundation

Acute Myeloid Leukemia Cells

Acute Myeloid Leukemia Cells
Harvard and MIT researchers discover that blood cancer cells (shown here) are less tolerant to shifts in their metabolism than their healthy counterparts.

Contact: Joseph Caputo
joseph_caputo@harvard.edu
617-496-1491
Harvard University

A Traditional Healer, Dar es Salaam

A Traditional Healer, Dar es Salaam
To improve treatment of psychosis in Tanzania, Grand Challenges Canada grantees will harness the power of ubiquitous mobile devices to bridge rural traditional healers and urban medical practitioners...

Contact: Terry Collins
tc@tca.tc
416-538-8712
Terry Collins Assoc

Sterile Drill Covers for Low-Cost Orthopedic Trauma Surgery

Sterile Drill Covers for Low-Cost Orthopedic Trauma Surgery
This low-cost, sterilizable cover enables the use of widely available commercial power drills for orthopedic trauma surgery in low-resource settings.

Contact: Terry Collins
tc@tca.tc
416-538-8712
Terry Collins Assoc

HPV Infographic

HPV Infographic
This is an infographic about human papillomavirus.

Contact: Kobi Print
kobi.print@sydney.edu.au
61-481-012-729
University of Sydney

Oncogenic lncRNA FAL1

Oncogenic lncRNA FAL1
This image depicts an oncogenic lncRNA FAL1 (the dragon) dysregulating gene transcription and promoting tumorigenesis. FAL1 stabilizes BMI1 (the stone) by associating with it (the dragon twine around ...

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Keytruda (3 of 3)

Keytruda (3 of 3)
The immune system is able to resume its attack by the white blood cells, shrinking the tumors.

Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-794-2262
University of California - Los Angeles Health Sciences

Keytruda (2 of 3)

Keytruda (2 of 3)
The new drug blocks the protein and breaks down the protective shield.

Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-794-2262
University of California - Los Angeles Health Sciences

Keytruda (1 of 3)

Keytruda (1 of 3)
White blood cells of our immune system attempt to attack a deadly melanoma cancer tumor, but are blocked by a protein that raises up from the cancer cell like a shield.

Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-794-2262
University of California - Los Angeles Health Sciences

Macrophages

Macrophages
In an inflammatory environment (left) and normal environment (right) macrophages (green) engulf dead cells (pink).

Contact: Salk Communications
press@salk.edu
Salk Institute

Mouse Model UBC13 Enzyme

Mouse Model UBC13 Enzyme
This image depicts a tumor with reduced levels of enzyme UBC13 (top) and a control tumor (bottom) that has spread to the lungs.

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Sabotaging a Cancer Cell

Sabotaging a Cancer Cell
In this image, lupus antibodies penetrate a nucleus.

Contact: Vicky Agnew
203-785-7001
Yale University

Activated Oncogene Spurs Production of Hydrogen Peroxide

Activated Oncogene Spurs Production of Hydrogen Peroxide
When the oncogene H-RAS is activated in a cell (right panel), the cell begins to produce hydrogen peroxide (tagged with a red fluorescent marker), a form of reactive oxygen species. It's the first ...

Contact: Peter Tarr
tarr@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory

Raman Spectrometer for Cancer Detection

Raman Spectrometer for Cancer Detection
A team led by researchers at Guangdong Medical College in China has demonstrated the potential of a new, non-invasive method to screen for prostate cancer, a common type of cancer in men worldwide.

Contact: Jason Socrates Bardi
jbardi@aip.org
240-535-4954
American Institute of Physics

HICCC Building

HICCC Building
This is the Herbert Irving Comprehensive Cancer Center building.

Contact: Lucky Tran
lt2549@columbia.edu
212-305-3689
Columbia University Medical Center

HICCC Research

HICCC Research
Research at the Herbert Irving Comprehensive Cancer Center.

Contact: Lucky Tran
lt2549@columbia.edu
212-305-3689
Columbia University Medical Center

Nf-Trip Suppresses Tumor Growth of HCC Orthotopic Model

Nf-Trip Suppresses Tumor Growth of HCC Orthotopic Model
This image proves that Nf-Trip suppresses tumor growth of HCC orthotopic model.

Contact: Han Bin Oh
ohanvin@ibs.re.kr
82-428-788-182
Institute for Basic Science

Nf-Trip for Hepatocellular Carcinoma Targeted Therapy

Nf-Trip for Hepatocellular Carcinoma Targeted Therapy
This is a illustration to explain about Nf-Trip for Hepatocellular Carcinoma (HCC) targeted therapy.

Contact: Han Bin Oh
ohanvin@ibs.re.kr
82-428-788-182
Institute for Basic Science

RUNK Proteins and Fanconi Anemia Factor

RUNK Proteins and Fanconi Anemia Factor
RUNX proteins (red) facilitate the recruitment of Fanconi anemia factor (green) to sites of DNA damage.

Contact: Kimberley Wang
kimberley.wang@nus.edu.sg
National University of Singapore

DNA Damage

DNA Damage
Persistent DNA damage, visualized by gammaH2AX staining (red dots), in hematopoietic stem cells could lead to leukemia.

Contact: Kimberley Wang
kimberley.wang@nus.edu.sg
National University of Singapore

Roving Receptors (1 of 2)

Roving Receptors (1 of 2)
Duke University's David Sherwood and his team are using live-cell imaging to probe living cells to see how they find their way to new tissues and organs in the body. In these time-lapse videos of an ...

Contact: Robin Ann Smith
ras10@duke.edu
919-681-8057
Duke University

Roving Receptors (2 of 2)

Roving Receptors (2 of 2)
Once the receptors locate the signal, they stay put in the region of the cell membrane that is closest to its source.

Contact: Robin Ann Smith
ras10@duke.edu
919-681-8057
Duke University

APC Ceta Catenin Colon

APC Ceta Catenin Colon
This is mouse colon tissue stained for APC (red), b-catenin (green), and nuclei (blue).

Contact: Brendan M. Lynch
blynch@ku.edu
785-864-8855
University of Kansas

Exosome Deployed

Exosome Deployed
Male fruit flies deploy exosomes to alter the mating behavior of females. Shown here, a close-up view (right) of the female reproductive tract (left) reveals a green exosome (arrow) on the surface.

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press

Botox Injection

Botox Injection
This image shows cells from the anterior (left) and posterior (right) halves of the stomach of mice with cancer. Only the anterior stomach half was injected with Botox®.

Contact: Lucky Tran
lt2549@cumc.columbia.edu
212-305-3689
Columbia University Medical Center

Botox Mechanism

Botox Mechanism
Botox® is taken in by the nerves, where it prevents the release of neurotransmitters.

Contact: Lucky Tran
lt2549@cumc.columbia.edu
212-305-3689
Columbia University Medical Center

Stomach Cells

Stomach Cells
This image shows stomach cells (red) growing with nerve cells (fluorescent green) in a lab culture dish.

Contact: Lucky Tran
lt2549@cumc.columbia.edu
212-305-3689
Columbia University Medical Center

Nanoparcticles Producing Logical Calculations

Nanoparcticles Producing Logical Calculations
This illustration shows nanoparcticles producing logical calculations.

Contact: Alexandra O. Borissova
borissova@phystech.edu
7-926-376-1175
Moscow Institute of Physics and Technology

Cells Passing Through EMT Chip

Cells Passing Through EMT Chip
As cells undergoing the epithelial-mesenchymal transition move from left to right through the EMT chip, those expressing mesenchymal markers (red) break away and move independently from other cells, ...

Contact: Katie Marquedant
kmarquedant@partners.org
617-726-0337
Massachusetts General Hospital

Leukemia Cell Image

Leukemia Cell Image
A leukemia cell coated with antibody is marked for destruction by activated natural killer cells.

Contact: Ellin Kavanagh
ekavanagh@chla.usc.edu
Children's Hospital Los Angeles

The Inner Workings of Scalpel

The Inner Workings of Scalpel
Each dot represents a short sequence of DNA from the reads mapped to a gene. The red path spells out the normal version of the gene, while the yellow path spells out a truncated path with the indel. ...

Contact: Jaclyn Jansen
jjansen@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory

The Dangers of Indels

The Dangers of Indels
The letters in the human genome carry instructions to make proteins, via a three-letter code. Each trio spells out a word, and the words are strung together in a sentence to build a specific protein. ...

Contact: Jaclyn Jansen
jjansen@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory

MD Anderson Teams up with Industry Leader to Improve Targeted Therapies in Metastatic Disease

MD Anderson Teams up with Industry Leader to Improve Targeted Therapies in Metastatic Disease
The University of Texas MD Anderson Cancer Center announced an alliance with Boston-based Foundation Medicine and the opening of a randomized-controlled trial called IMPACT2 to determine whether ...

Contact: William Fitzgerald
wbfitzgerald@mdanderson.org
713-792-9518
University of Texas M. D. Anderson Cancer Center

Imaging Cancer Cell Invasion (2 of 2)

Imaging Cancer Cell Invasion (2 of 2)
Cancer cells advance across a microchip designed to be an obstacle course for cells. The device sheds new light on how cancer cells invade and could be used to test drugs aimed at preventing cancer ...

Contact: Kevin Stacey
kevin_stacey@brown.edu
401-863-3766
Brown University

Imaging Cancer Cell Invasion (1 of 2)

Imaging Cancer Cell Invasion (1 of 2)
Cancer cells advance across a microchip designed to be an obstacle course for cells. The device sheds new light on how cancer cells invade and could be used to test drugs aimed at preventing cancer ...

Contact: Kevin Stacey
kevin_stacey@brown.edu
401-863-3766
Brown University

Skeletal Abnormalities in Neurofibromatosis

Skeletal Abnormalities in Neurofibromatosis
Mice missing the gene neurofibromin in bone cells have more non-calcified bone (osteoid), shown in pink, compared to normal mice. In this image, calcified bone is black and bone-forming osteoblasts ...

Contact: Leigh MacMillan
leigh.macmillan@vanderbilt.edu
615-322-4747
Vanderbilt University Medical Center

Deaths Rise with Shift from In-Hospital to Outpatient Procedures for Urology Surgeries

Deaths Rise with Shift from In-Hospital to Outpatient Procedures for Urology Surgeries
Jesse D. Sammon, D.O., a researcher at Henry Ford's Vattikuti Urology Institute and lead author of the study discusses deaths rise with shift from in-hospital to outpatient procedures for common ...

Contact: Dwight Angell
dwight.angell@hfhs.org
313-876-8709
Henry Ford Health System

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