IMAGE: Lung squamous cell carcinoma

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Researchers Overcome Radiation Resistance in Leukemia With an Engineered Precision Medicine

Researchers Overcome Radiation Resistance in Leukemia With an Engineered Precision Medicine
CD19L-sTRAIL selectively binds to the CD19 receptor on leukemia cells via its CD19L moiety upon which its sTRAIL component kills the cells by engaging the TRAIL death receptors.

Contact: Sacha Boucherie
s.boucherie@elsevier.com
31-204-853-564
Elsevier

Cross Section of a Pubertal Mouse Mammary Duct

Cross Section of a Pubertal Mouse Mammary Duct
Id4+ stem cells are in red, luminal cells in green, and all cells are marked with blue nuclear dye.

Contact: Alison Heather
a.heather@garvan.org.au
61-292-958-128
Garvan Institute of Medical Research

MRI of Healthy Cells Vs. Cancer Cells

MRI of Healthy Cells Vs. Cancer Cells
Normal cells (left) have far more sugar attached to mucin proteins than do cancerous cells (right). Mucin-attached sugar generates a high MRI signal, shown in red.

Contact: Shawna Williams
shawna@jhmi.edu
410-955-8236
Johns Hopkins Medicine

Stainless Staining

Stainless Staining
Breast tissue is computationally stained using data from infrared imaging without actually staining the tissue, enabling multiple stains on the same sample. From left, the image shows a Hematoxylin ...

Contact: Liz Ahlberg
eahlberg@illinois.edu
217-244-1073
University of Illinois at Urbana-Champaign

Molecular Labeling Machine

Molecular Labeling Machine
Scientists found the enzyme METTL3 (green) tags a particular sequence within RNA molecules destined to become gene-regulating microRNAs. While this happens within cells' nuclei (blue), METTL3 is also ...

Contact: Wynne Parry
wparry@rockefeller.edu
212-327-7789
Rockefeller University

Brain Tumor Cells Decimated by Mitochondrial

Brain Tumor Cells Decimated by Mitochondrial
The new drug MP-MUS (yellow) attacks cancer cell mitochondria by infiltrating both inner and outer membranes (green) after being converted from an inactive, non-toxic form to an active, toxic form by ...

Contact: Gale Smith
gsmith@houstonmethodist.org
281-627-0439
Houston Methodist

CK1α: The Achilles Heel of RAS-Driven Cancer Cells

CK1α: The Achilles Heel of RAS-Driven Cancer Cells
Removal of enzyme CK1α blocks cellular digestion in specific cancers.

Contact: Dharshini Subbiah
dharshini.subbiah@duke-nus.edu.sg
659-616-7532
Duke-NUS Graduate Medical School Singapore

Stress Granules Linked to Metastasis

Stress Granules Linked to Metastasis
The time-lapse video shows how the proteins YB-1 (green) and G3BP1 (red) overlap in stress granules, structures whose prevalence in tumors researchers now link to metastasis.

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press

Stress Granules in Tumors

Stress Granules in Tumors
Fewer stress granules (yellow) occur in cancer cells lacking G3BP1 (right) than in controls (left). Nuclei are labeled blue.

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press

Recruiting Dendritic Cells for Cancer Fight

Recruiting Dendritic Cells for Cancer Fight
This is an artist's representation of the surface of a human dendritic cell.

Contact: Barbara McMakin
nindspressteam@ninds.nih.gov
NIH/National Institute of Neurological Disorders and Stroke

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