IMAGE: Lung squamous cell carcinoma

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Epigenome

Epigenome
This is an example of an epigenome derived from a tumor sample included in study. Green fluorescence signals indicate a loss of epigenetic signal, while red indicates a gain of epigenetic signal.

Contact: Gemma Fornons
gfornons@idibell.cat
0034-638-685-074
IDIBELL-Bellvitge Biomedical Research Institute

Melanoma

Melanoma
A new study finds that melanoma screening by primary care providers did not lead to a potentially problematic spike in dermatologist visits or skin surgeries.

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University

Let-7 and Neuroblastoma Survival

Let-7 and Neuroblastoma Survival
These survival curves, based on 202 patients with neuroblastoma, show that chromosomal let-7 loss reduces survival in both MYCN-amplified and non-MYCN-amplified neuroblastoma. With a larger patient ...

Contact: Keri Stedman
keri.stedman@childrens.harvard.edu
617-919-3110
Boston Children's Hospital

Two Ways Neuroblastoma Takes out let-7

Two Ways Neuroblastoma Takes out let-7
This Venn diagram shows that most patients with neuroblastoma lose let-7 through a single mechanism, but rarely both together. In about 25 percent of patients, the oncogene MYCN is amplified, whereas ...

Contact: Keri Stedman
keri.stedman@childrens.harvard.edu
617-919-3110
Boston Children's Hospital

Basal Cell Carcinoma

Basal Cell Carcinoma
The green-labelled cells show a basal cell carcinoma in mouse tail epidermis derived from a single mutant stem cell and expanding out of the normal epidermis stained in red.

Contact: Craig Brierley
craig.brierley@admin.cam.ac.uk
44-012-237-66205
University of Cambridge

Gene Silencing at Breast Cancer Cells

Gene Silencing at Breast Cancer Cells
Immunofluorescent breast cancer cells used in this study. Green fluorescent shows the phosphorylated progesterone receptor at Serine 294 and red fluorescent signal shows the same progesterone receptor...

Contact: Laia Cendros
laia.cendros@crg.eu
34-607-611-798
Center for Genomic Regulation

In the Absence of Disabled-2 , Vps34/Beclin-1 Interactions are Maintained

In the Absence of Disabled-2 , Vps34/Beclin-1 Interactions are Maintained
Immunofluorescence analysis to detect the expression and localization of Vps34 and Beclin-1 in cathepsin B overexpressing mouse mammary epithelial (CTSB/OE cells) treated -/+ TGF-beta? for 7 days. ...

Contact: Heather Woolwine
woolwinh@musc.edu
843-792-7669
Medical University of South Carolina

Electric Therapy

Electric Therapy
This is a photo of three microfluidic devices filled with food color dyes. The device, about the size of a credit card, is designed to help scientists narrow in on safe ranges of electric fields that ...

Contact: Sarah McDonnell
s_mcd@mit.edu
617-253-8923
Massachusetts Institute of Technology

Going to 'Wars' against Cancer and Heart Disease

Going to 'Wars' against Cancer and Heart Disease
This is a microscopic view to show blood vessel formation or angiogenesis at high resolution. Left: Normal blood vessel formation throughout the body during development of a zebrafish embryo. Right: ...

Contact: Yen May Ong
yenmay.ong@duke-nus.edu.sg
65-660-12057
Duke-NUS Medical School

Mitochondria Stress and Cancer

Mitochondria Stress and Cancer
Mitochondrial stress induces expression of nearly 120 genes involved in cell metabolism, morphology, resistance to apoptosis and cell invasion in addition upregulation of p53 by reduced expression of ...

Contact: Katherine Unger Baillie
kbaillie@upenn.edu
215-898-9194
University of Pennsylvania

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