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Key: Meeting
Showing releases 1-25 out of 1176.
Public Release: 18-Jun-2013
 Cancer Prevention ResearchFat cells in breast may connect social stress to triple-negative breast cancer Local chemical signals released by fat cells in the mammary gland appear to provide a crucial link between exposure to unrelenting social stressors early in life, and the subsequent development of aggressive breast cancer. 
National Institutes of Health, US Army, Department of Defense
Contact: John Easton
Public Release: 18-Jun-2013
PLOS ONEUT Dallas study suggests new approach to fight lung cancer Recent research has shown that cancer cells have a much different -- and more complex -- metabolism than normal cells. Now, scientists at the University of Texas at Dallas have found that exploiting these differences might provide a new strategy to combat lung cancer.
NIH/National Cancer Institute
Contact: Amanda Siegfried
Public Release: 18-Jun-2013
CellAn article in 'Cell' reveals a new resistance mechanism to chemotherapy in breast and ovarian cancer The team led by Spanish National Cancer Research Centre researcher Óscar Fernández-Capetillo, head of the Genomic Instability Group, together with researchers from the National Cancer Institute in the US, have participated in a study that describes the causes that explain why tumors with BRCA1 and BRCA2 mutations stop responding to PARP inhibitor drugs. Contact: Press Office
Public Release: 18-Jun-2013
OncogeneStudy shows how the Nanog protein promotes growth of head and neck cancer Researchers have identified a biochemical pathway in cancer stem cells that is essential for promoting head and neck cancer. The study shows that a protein called Nanog, which is normally active in embryonic stem cells, promotes the growth of cancer stem cells in head and neck cancer. The findings provide information essential for designing novel targeted drugs that might improve the treatment of head and neck cancer.
NIH/National Cancer Institute, American Cancer Society, Joan Bisesi Fund
Contact: Darrell E. Ward
Public Release: 18-Jun-2013
Cancer CellScientists catch EGFR passing a crucial message to cancer-promoting protein Researchers have discovered and mapped the signaling network between two previously unconnected proteins, exposing a link that, if broken, could cut off cancer cell growth at its starting point. Contact: Scott Merville
Public Release: 18-Jun-2013
Proceedings of the National Academy of SciencesChemical probe confirms that body makes its own rotten egg gas, H2S, to benefit health A new study confirms directly what scientists previously knew only indirectly -- that poisonous "rotten egg" gas hydrogen sulfide is generated by the body's blood vessel cells. Researchers made the confirmation by developing a chemical probe that lights up in reaction to rotten egg gas. The scientists observed the process in real-time through a microscope, said chemist Alexander Lippert, Southern Methodist University, Dallas. "This is going to open up many experiments for scientists," Lippert said.
National Institutes of Health, Packard Foundation, Howard Hughes Medical Institute, Amgen
Contact: Margaret Allen
Public Release: 17-Jun-2013
ENDO 2013Exposure to BPA in developing prostate increases risk of later cancer Early exposure to BPA (bisphenol A) -- an additive commonly found in plastic water bottles and soup can liners -- causes an increased cancer risk in an animal model of human prostate cancer, according to University of Illinois at Chicago researcher Gail Prins.
NIH/National Institute of Environmental Sciences
Contact: Sharon Parmet
Public Release: 17-Jun-2013
ENDO 2013Exposure to low doses of BPA linked to increased risk of prostate cancer in human stem cells Exposing developing tissue to low levels of the plastic bisphenol A, commonly known as BPA, is linked to a greater incidence of prostate cancer in tissue grown from human prostate stem cells, a new study finds. The results will be presented Monday, June 17, at The Endocrine Society's 95th Annual Meeting in San Francisco. Contact: Jenni Glenn Gingery
Public Release: 17-Jun-2013
Cancer DiscoveryAbnormalities in new molecular pathway may increase breast cancer risk A new molecular pathway involving the gene ZNF365 has been identified and abnormalities in that pathway may predict worse outcomes for patients with breast cancer, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research. Contact: Jeremy Moore
Public Release: 17-Jun-2013
Journal of Clinical InvestigationJCI early table of contents for June 17, 2013 This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, June 17, 2013, in the JCI: Scouring the genome of adenoid cystic carcinoma; Variants in the SIM1 gene are associated with obesity; Vitamin B3 blocks cyst formation in a mouse model of polycystic kidney disease; and many more. Contact: Jillian Hurst
Public Release: 17-Jun-2013
Biology of Blood and Marrow TransplantationCertain types of graft-versus-host disease may increase risk of death, Moffitt researcher says Joseph Pidala, M.D., M.S., assistant member of the Blood and Bone Marrow Transplant and Immunology programs at Moffitt Cancer Center, and colleagues from the Chronic Graft-Versus-Host Disease Consortium have determined that certain gastrointestinal and liver-related types of chronic graft-versus-host disease are associated with worsened quality of life and death.
NIH/National Cancer Institute
Contact: Kim Polacek
Public Release: 17-Jun-2013
Journal of Clinical InvestigationScouring the genome of adenoid cystic carcinoma In this issue of the Journal of Clinical Investigation, researchers led by Andrew Futreal at the Wellcome Trust Sanger Institute in Cambridge, MA, performed a type of genetic sequencing known as whole exome sequencing of 24 ACC cases.
National Institutes of Health, Adenoid Cystic Carcinoma Research Foundation, Wellcome Trust
Contact: Jillian Hurst
Public Release: 17-Jun-2013
Journal of the National Cancer InstituteTimeline reforms increase initiation speed of NCI sponsored clinical trials The National Cancer Institute and investigators have reduced the deadlines for initiation of trials with the goal of reaching more patients in need of new treatments, according to a study published June 17 in the Journal of the National Cancer Institute. Contact: Zachary Rathner
Public Release: 17-Jun-2013
ENDO 2013Diabetics who use meters to monitor their glucose have better control over disease Mount Sinai researchers will demonstrate new data on diabetes self-management, as well as the role of prostastic acid phosphatase in Prostate Cancer bone metastases; identify new molecules that can stimulate the thyroid gland; reveal the prevalence of primary aldosteronism; and show how thyroid autoimmunity may be triggered by endoplasmic reticulum stress. Contact: Renatt Brodsky
Public Release: 17-Jun-2013
ENDO 2013Preventing eggs' death from chemotherapy Young women who have cancer treatment often lose their fertility because chemotherapy and radiation can damage or kill their immature ovarian eggs, called oocytes. Now, Northwestern Medicine® scientists have found the molecular pathway that can prevent the death of immature ovarian eggs due to chemotherapy, potentially preserving fertility and endocrine function. Scientists achieved this in mice by adding a currently approved chemotherapy drug, imatinib mesylate, to another chemotherapy drug cisplatin.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development
Contact: Marla Paul
Public Release: 17-Jun-2013
Clinical OncologyNIH scientists find promising biomarker for predicting HPV-related oropharynx cancer Researchers have found that antibodies against the human papillomavirus may help identify individuals who are at greatly increased risk of HPV-related cancer of the oropharynx, which is a portion of the throat that contains the tonsils.
NIH/National Cancer Institute
Contact: NCI Press Office
Public Release: 17-Jun-2013
Annals of Internal MedicineOHSU review: Previous studies overstated evidence on Medtronic spinal fusion product An analysis by the Evidence-based Practice Center at Oregon Health & Science University has found that previously published clinical trial studies about a controversial bone growth product used in spinal surgeries overstated the product's effectiveness.
Yale University Open Data Access
Contact: Todd Murphy
Public Release: 17-Jun-2013
PLOS GeneticsAspirin may fight cancer by slowing DNA damage Aspirin is known to lower risk for some cancers, and a new study led by a UC San Francisco scientist points to a possible explanation, with the discovery that aspirin slows the accumulation of DNA mutations in abnormal cells in at least one pre-cancerous condition. Contact: Jeffrey Norris
Public Release: 17-Jun-2013
ENDO 2013New medication treats drug-resistant prostate cancer in the laboratory A new drug called pyrvinium pamoate inhibits aggressive forms of prostate cancer that are resistant to standard drugs, according to a study conducted in an animal model. The results will be presented Monday at The Endocrine Society's 95th Annual Meeting in San Francisco. Contact: Aaron Lohr
Public Release: 17-Jun-2013
New England Journal of MedicineA new target for cancer drug development Harvard Stem Cell Institute researchers have identified in the most aggressive forms of cancer a gene known to regulate embryonic stem cell self-renewal, beginning a creative search for a drug that can block its activity. Contact: B. D. Colen
Public Release: 17-Jun-2013
Annals of Internal MedicineObservation is safe, cost-saving in low-risk prostate cancer Dana-Farber researchers find many men with low-risk, localized prostate cancers can safely choose observation instead of undergoing immediate treatment and a have better quality of life while reducing health care costs.
NIH/National Cancer Institute, US Department of Defense, Prostate Cancer Foundation
Contact: Teresa Herbert
Public Release: 17-Jun-2013
Surgical EndoscopyNew alternative to surgery lets doctors remove suspicious polyps, keep colon intact A UCLA team of surgeons and gastroenterologists has been performing a new, minimally invasive procedure to remove large and hard-to-reach polyps while keeping the colon intact. The procedure, which combines two minimally invasive techniques, has currently been performed at only a handful of medical centers in the United States. Contact: Rachel Champeau
Public Release: 17-Jun-2013
Genes & DevelopmentStudy identifies protein essential for normal heart function A study by researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences and the Department of Pharmacology at the University of California, San Diego, shows that a protein called MCL-1, which promotes cell survival, is essential for normal heart function.
National Institutes of Health
Contact: Debra Kain
Public Release: 16-Jun-2013
Nature Cell Biology'Chase and run' cell movement mechanism explains process of metastasis A mechanism that cells use to group together and move around the body -- called 'chase and run' -- has been described for the first time by scientists at UCL.
Medical Research Council, Wellcome Trust
Contact: Clare Ryan
Public Release: 15-Jun-2013
ENDO 2013Source of tumor growth in aggressive prostate cancer found Researchers have discovered a molecular switch that explains, at least in part, how some fast-growing prostate cancers become resistant to hormone treatment, a new study conducted in human cell cultures and mice finds. The results were presented Saturday at The Endocrine Society's 95th Annual Meeting in San Francisco. Contact: Jenni Glenn Gingery
Showing releases 1-25 out of 1176.
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