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Showing releases 1-25 out of 1216.
Public Release: 1-Aug-2013
 CellBlocking sugar intake may reduce cancer risk or progression in obese and diabetic people Blocking dietary sugar and its activity in tumor cells may reduce cancer risk and progression, according to researchers from the Icahn School of Medicine. The study, conducted in fruit flies and published in the journal Cell, provides insight as to why metabolism-related diseases such as diabetes or obesity are associated with certain types of cancer, including pancreatic, breast, liver, and colon cancers. Contact: Mount Sinai Press Office
Public Release: 1-Aug-2013
ASTRO applauds new GAO report on physician self-referral abuse ASTRO Chairman Michael L. Steinberg, M.D., FASTRO, called attention to the Government Accountability Office's striking report released today, "Medicare: Higher Use of Costly Prostate Cancer Treatment by Providers Who Self-Refer Warrants Scrutiny," that details clear mistreatment of patients who trusted their physicians to care for their prostate cancer. Contact: Michelle Kirkwood
Public Release: 1-Aug-2013
CarcinogenesisFatty acids could aid cancer prevention and treatment Omega-3 fatty acids, contained in oily fish such as salmon and trout, selectively inhibit growth and induce cell death in early and late-stage oral and skin cancers, according to new research from scientists at Queen Mary, University of London. Contact: Katrina Coutts
Public Release: 1-Aug-2013
Molecular CellSanford-Burnham researchers map a new metabolic pathway involved in cell growth Deciphering the body's complex molecular pathways that lead to disease when they malfunction is highly challenging. Researchers at Sanford-Burnham Medical Research Institute now have a more complete picture of one particular pathway that can lead to cancer and diabetes. In the study published by Molecular Cell, the scientists uncovered how a protein called p62 has a cascade affect in regulating cell growth in response to the presence of nutrients such as amino acids and glucose. 
National Institutes of Health
Contact: Deborah Robison
Public Release: 1-Aug-2013
CellNew target for the fight against cancer as a result of excessive blood vessel formation New blood vessel formation (angiogenesis) stimulates the growth of cancer and other diseases. Anti-angiogenic inhibitors slow down cancer growth by disrupting the blood supply to the tumor. To date, the success of these treatments is limited by resistance, poor efficiency and harmful side effects. In the leading scientific journal Cell, Peter Carmeliet (VIB-KU Leuven) and his team reported that sugar metabolism (a process that we call glycolysis) also plays an essential role in the formation of new blood vessels. Contact: Kris Van der Beken
Public Release: 1-Aug-2013
Cell Stem CellBoning up: McMaster researchers find home of best stem cells for bone marrow transplants McMaster University researchers have revealed the location of human blood stem cells that may improve bone marrow transplants. The best stem cells are at the ends of the bone.
Canadian Institutes of Health Research, Ontario Cancer Research Institute
Contact: Thana Dharmarajah
Public Release: 1-Aug-2013
ScienceScientists find long-sought method to efficiently make complex anticancer compound Scientists at the Scripps Research Institute have achieved the first efficient chemical synthesis of ingenol, a highly complex, plant-derived compound of interest to drug developers for its anticancer potential. The achievement will enable scientists to synthesize a wide variety of ingenol derivatives and investigate their therapeutic properties. The achievement also sets the stage for the efficient commercial production of ingenol mebutate, an existing anticancer drug that at present must be extracted inefficiently from plants.
LEO Pharma, Carlsberg Foundation, Danish Council for Independent Research, Alexander von Humboldt Foundation
Contact: Mika Ono
Public Release: 1-Aug-2013
American Journal of Physiology - Renal PhysiologyResearch hope for bladder cancer Researchers from Plymouth University in the UK have for the first time identified the mechanism that causes a small, benign polyp to develop into severe invasive bladder cancer. Contact: Andrew Gould
Public Release: 1-Aug-2013
Journal of Biological ChemistryStudy highlights possible new approach to prostate cancer treatment A study in the Journal of Biological Chemistry identifies a new therapeutic approach to treat prostate cancer. The research shows that expression of the FoxM1 protein is essential for prostate cancer to develop in mouse models. The study also shows that depletion of FoxM1 in prostate epithelial cells inhibits tumor cell proliferation, the process by which new blood vessels are formed, and metastasis -- the spread of cancer to other organs of the body.
National Institutes of Health, Department of Defense
Contact: Nick Miller
Public Release: 1-Aug-2013
CellTargeted therapy identified for protein that protects and nourishes cancer UT MD Anderson scientists identify the first targeted therapy to block Skp2, which suppresses a cellular defense against cancer and activates glycolysis to feed tumors. The drug restores the senescence program and stifles glycolysis to thwart tumor progression.
NIH/National Cancer Institute, American Cancer Society, Susan G. Komen for the Cure
Contact: Scott Merville
Public Release: 1-Aug-2013
Cancer CellBlocking key enzyme in cancer cells could lead to new therapy Researchers from the University of Illinois at Chicago College of Medicine have identified a characteristic unique to cancer cells in an animal model of cancer -- and they believe it could be exploited as a target to develop new treatment strategies.
National Institutes of Health, US Department of Veterans Affairs, UIC Center for Clinical and Translational Sciences, Chicago Biomedical Consortium, The Searle Funds
Contact: Sharon Parmet
Public Release: 1-Aug-2013
FASEB JournalFetal stress disrupts the way genes are transmitted Stress might have harmed your health even before you were born. In a new report in The FASEB Journal, Harvard researchers find that epigenetic disruptions associated with chronic disease later in life are already common at birth. These aberrations result from stressors in the intrauterine environment (maternal smoking, diet, or high levels of endocrine-disrupting chemicals). Consequently, the seeds of disease may be sown before birth, increasing the importance of optimal prenatal care. Contact: Cody Mooneyhan
Public Release: 1-Aug-2013
PLOS GeneticsGenetics: More than merely a mutated gene If two women have the same genetic mutation that puts them at higher-than-average risk for a disease such as breast cancer, why does only one develop the disease?
National Science Foundation
Contact: Layne Cameron
Public Release: 1-Aug-2013
ScienceScientists discover new type of protein modification, may play role in cancer and diabetes Scientists at the Scripps Research Institute have discovered a new type of chemical modification that affects numerous proteins within mammalian cells. The modification appears to work as a regulator of important cellular processes including the metabolism of glucose. Further study of this modification could provide insights into the causes of diabetes, cancer and other disorders.
National Institutes of Health, Skaggs Institute for Chemical Biology, Damon Runyon Cancer Research Foundation
Contact: Mika Ono
Public Release: 1-Aug-2013
Cell ReportsNovel drug shuts down master protein key to lymphoma Researchers have discovered how an experimental drug is capable of completely eradicating human lymphoma in mice after just five doses. The study, led by researchers at Weill Cornell Medical College, sets the stage for testing the drug in clinical trials of diffuse large B-cell lymphoma, the most common subtype of non-Hodgkin lymphoma, itself the seventh most frequently diagnosed cancer in the US.
NIH/National Cancer Institute, National Science Foundation, Chemotherapy Foundation
Contact: John Rodgers
Public Release: 1-Aug-2013
Journal of the American Academy of DermatologyWhen it comes to skin cancer, pictures are worth 1,000 words Seeing pictures of skin cancer motivates people to regularly check their own moles, according to a new research paper from the School of Public Health and Health Systems at the University of Waterloo. Contact: Nick Manning
Public Release: 1-Aug-2013
BiomicrofluidicsCatching cancer early by chasing it Reaching a clinic in time to receive an early diagnosis for cancer -- when the disease is most treatable -- is a global problem. And now a team of Chinese researchers proposes a global solution: have a user-friendly diagnostic device travel to the patient, anywhere in the world. Contact: Jason Socrates Bardi
Public Release: 1-Aug-2013
Cancer ResearchUPCI researchers target 'cell sleep' to lower chances of cancer recurrence By preventing cancer cells from entering a state of cellular sleep, cancer drugs are more effective, and there is a lower chance of cancer recurrence, according to new research from an international research team led by University of Pittsburgh Cancer Institute scientists. The discovery is the first to show that it is possible to therapeutically target cancer cells to keep them from entering a cellular state called quiescence, or "cell sleep."
American Cancer Society, GIST Cancer Research Fund, Life Raft Group
Contact: Allison Hydzik
Public Release: 1-Aug-2013
Science Translational MedicineA roadblock to personalized cancer care? Leading experts in cancer treatment and research, including university researchers, industry and insurance providers, have published a paper urging more focus and attention on the field of research that involves identifying genetic and molecular markers that help guide cancer treatment. The current attitude toward biomarker research has led to a vicious cycle that undervalues the crucial role these kinds of tests play in developing personalized cancer treatments. Contact: Nicole Fawcett
Public Release: 31-Jul-2013
Journal of Chemical PhysicsVCU physicists discover theoretical possibility of large, hollow magnetic cage molecules Virginia Commonwealth University researchers have discovered, in theory, the possibility of creating large, hollow magnetic cage molecules that could one day be used in medicine as a drug delivery system to non-invasively treat tumors, and in other emerging technologies.
US Department of Energy
Contact: Sathya Achia Abraham
Public Release: 31-Jul-2013
New poll shows minority populations support clinical trials to improve health of others Altruism is a strong motivating factor for clinical trial participation in the general population and even more so among several minority groups. A significant percentage of African-Americans (61 percent), Hispanics (57 percent) and Asians (50 percent) say it's very important to participate as a volunteer in a clinical trial to improve the health of others, compared to 47 percent of non-Hispanic whites, according to a new national public opinion poll commissioned by Research!America. Contact: Anna Briseno
Public Release: 31-Jul-2013
Chemotherapy Research and PracticeNew therapy improves life span in melanoma patients with brain metastases, SLU researchers find The treatment, given to patients with brain metastases, triggers the body's own immune system to recognize and destroy cancer cells. Contact: Riya Anandwala
Public Release: 31-Jul-2013
Journal of the American College of CardiologyFertility therapy not associated with long-term cardiovascular disease Women who gave birth following fertility treatment had no long-term increased risk of death or major cardiovascular events compared to women who gave birth without fertility therapy, according to new research by the Institute for Clinical Evaluative Sciences and Women's College Hospital. Contact: Julie Saccone
Public Release: 31-Jul-2013
Nature CommunicationsUnderstanding the effects of genes on human traits Recent technological developments in genomics have revealed a large number of genetic influences on common complex diseases, such as diabetes, asthma, cancer or schizophrenia. However, discovering a genetic variant predisposing to a disease is only a first step. In a study published today in Nature Communications, Montreal researchers with colleagues from Texas, propose a novel approach for scanning the entire genome that will help us understand the effect of genes on human traits.
National Institutes of Health, Genome Canada, Genome Quebec
Contact: Julie Robert
Public Release: 31-Jul-2013
Cell Stem CellCross-country collaboration leads to new leukemia model They were postdocs at Stanford when they first began considering the problem. Eight years later, and a continent apart, they found the answer. Contact: B. D. Colen
Showing releases 1-25 out of 1216.
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