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Showing releases 1-25 out of 1310.

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Public Release: 5-Oct-2015
Identifying cancer's food sensors may help to halt tumor growth
Oxford University researchers have identified a protein used by tumors to help them detect food supplies. Initial studies show that targeting the protein could restrict cancerous cells' ability to grow. Anonymous tumor samples from patients with colorectal cancer were compared to the known outcomes for the patients. Those who had higher levels of PAT4 in their tumors did less well than those with lower levels -- being more likely to relapse and die.
Cancer Research UK, Wellcome Trust, Biotechnology and Biological Sciences Research Council, British Province of the Society of Jesus

Contact: Tom Calver
University of Oxford

Public Release: 5-Oct-2015
Annals of Internal Medicine
Should women have an annual pelvic exam? Depends on who you ask
Below is a summary of articles being featured in the next issue of Annals of Internal Medicine. Annals of Internal Medicine attribution is required for all coverage.

Contact: Cara Graeff
American College of Physicians

Public Release: 5-Oct-2015
Nature Structural & Molecular Biology
Study reveals key structure in telomerase enzyme, a target for cancer drugs
Researchers at UC Santa Cruz have determined the structure of a key part of the enzyme telomerase, which is active in most cancers and enables cancer cells to proliferate indefinitely. The new findings reveal how the enzyme carries out a crucial function involved in protecting the ends of chromosomes.
National Institutes of Health

Contact: Tim Stephens
University of California - Santa Cruz

Public Release: 5-Oct-2015
JAMA Pediatrics
Disparities in outcomes for rare pediatric cancer suggest unequal access to primary care
Disparities in outcomes for children with retinoblastoma -- a rare eye tumor usually discovered in routine pediatric check-ups -- suggest unequal access to primary care, researchers from Dana-Farber/Boston Children's Cancer and Blood Disorders Center report in a study published in the journal JAMA Pediatrics. Although virtually all the children in the study survived, Hispanic children and children who lived in disadvantaged areas were more likely to lose an eye due to late diagnosis.

Contact: Irene Sege
Dana-Farber Cancer Institute

Public Release: 5-Oct-2015
A genetic polymorphism associated with lung cancer progression
Researchers at the Hiroshima University and Saitama Medical University found that in patients with lung cancer, a single nucleotide polymorphism may regulate gene and protein expression and be associated with poor prognosis. To establish this genetic polymorphism as a useful clinical prognostic marker and to further clarify its molecular mechanism, large-scale clinicopathological studies of lung cancer and/or other types of cancer are required for additional insights.
Japan Society for the Promotion of Science, Japanese Ministry of Education, Culture, Sports, Science and Technology, and others

Contact: Norifumi Miyokawa
Hiroshima University

Public Release: 5-Oct-2015
Study finds high HPV prevalence in subset of Peruvian men
A few years ago, Brandon Brown of UC Riverside assembled a team of researchers in Lima, Peru. The result of their work is the first study in that country to report human papillomavirus (HPV) infection in men who have sex with men (MSM) in multiple anatomical sites and suggesting benefit of the HPV vaccine in this population. The study is the first to examine HPV epidemiology and concordance at multiple anatomical sites in Peruvian MSM.
Merck & Co., Inc.

Contact: Iqbal Pittalwala
University of California - Riverside

Public Release: 5-Oct-2015
Journal of Urology
UTMB study shows testosterone therapy does not increase aggressive prostate cancer risk
A new population-based study from The University of Texas Medical Branch at Galveston showed for the first time that exposure to testosterone therapy over a five-year period was not associated with an increased risk of aggressive prostate cancer. Further, risk of high-grade prostate cancer did not increase according to the total number of testosterone injections. The study is available in the Journal of Urology.
National Institutes of Health, UTMB Sealy Center for Vaccine Development

Contact: Donna Ramirez
University of Texas Medical Branch at Galveston

Public Release: 4-Oct-2015
Scientific Reports
Predictive model could help guide choices for breast cancer therapies
Biomedical engineers have demonstrated a proof-of-principle technique that could give women and their oncologists more personalized information to help them choose options for treating breast cancer.
Georgia Research Alliance

Contact: John Toon
Georgia Institute of Technology

Public Release: 1-Oct-2015
Genome Research
New method to predict increased risk of non-familial breast cancer
By detecting cancer at an early stage, or even predicting who has an increased risk of being affected, the possibilities to treat the disease can be radically improved. In an international study led from Uppsala University the researchers have discovered that apparently healthy breast cells contain genetic aberrations that can be associated with an increased risk for non-familial breast cancer. The results have been published in the journal Genome Research.

Contact: Jan Dumanski
Uppsala University

Public Release: 1-Oct-2015
Lung Cancer
What is the cost of lung cancer in Germany?
With more than 50,000 newly diagnosed cases each year, lung cancer is one of the most common types of cancer in Germany. As yet, however, very few statistics are available on the care situation of lung cancer sufferers and the associated costs. Scientists at the Helmholtz Zentrum München have now analyzed comprehensive health insurance data in order to discover the cost of the disease and which treatment has the best prognosis. Their findings have been published in the medical journal Lung Cancer.

Contact: Dr. Larissa Schwarzkopf
Helmholtz Zentrum München - German Research Center for Environmental Health

Public Release: 1-Oct-2015
Neurology: Neuroimmunology & Neuroinflammation
New study removes cancer doubt for multiple sclerosis drug
Researchers from Queen Mary University of London are calling on the medical community to reconsider developing a known drug to treat people with relapsing multiple sclerosis (MS) after new evidence shows it does not increase the risk of cancer as previously thought.

Contact: Neha Okhandiar
Queen Mary, University of London

Public Release: 1-Oct-2015
Molecular Cell
Research connects specific variations in RNA splicing with breast cancer causation
Researchers have identified cellular changes traceable to an RNA splicing factor that's also an oncoprotein that may play a role in converting normal breast cells into tumors. Targeting these changes could potentially lead to therapies for some forms of breast cancer
NIH/National Cancer Institute, Swiss National Science Foundation, Susan B. Komen Foundation for the Cure, and Terri Brodeur Breast Cancer Foundation

Contact: Peter Tarr
Cold Spring Harbor Laboratory

Public Release: 1-Oct-2015
Nature Communications
Major study finds 5 new genetic variants linked to brain cancer
The biggest ever study of DNA from people with glioma -- the most common form of brain cancer -- has discovered five new genetic variants associated with the disease. Researchers said their findings provided important new evidence for an inherited susceptibility to glioma, and offered potential clues for how to treat or prevent the disease.
Cancer Research UK, Wellcome Trust, DJ Fielding Medical Research Trust

Contact: Henry French
Institute of Cancer Research

Public Release: 1-Oct-2015
Clinical Cancer Research
Investigational KW-0761 efficiently depletes immune system-suppressing Treg cells
In a phase Ia clinical trial, immune cells called Tregs, which can inhibit anticancer immune responses, were efficiently eliminated from the blood of patients with lung or esophageal cancer by treatment with the investigational therapeutic antibody KW-0761.
Ministry of Health, Labour, and Welfare of Japan; Ministry of Education, Culture, Sports, Science, and Technology of Japan; Japan Society for the Promotion of Science

Contact: Lauren Riley
American Association for Cancer Research

Public Release: 1-Oct-2015
JAMA Oncology
Women getting BRCA testing not receiving counseling by trained genetics professionals
Most women who underwent BRCA genetic testing did not receive genetic counseling by trained genetics professionals and the lack of clinician recommendation was the most commonly reported reason in a study of commercially insured women, according to an article published online by JAMA Oncology.

Contact: Anne DeLotto Baier
The JAMA Network Journals

Public Release: 1-Oct-2015
European Society for Paediatric Endocrinology Annual Meeting
Link between height and cancer
Cancer risk has been found to increase with height in both Swedish men and women, according to research presented today at the 54th Annual European Society for Paediatric Endocrinology Meeting. This long-term study is the largest carried out on the association between height and cancer in both genders.

Contact: Dr. Fiona Docherty
BioScientifica Limited

Public Release: 1-Oct-2015
Developmental Cell
The solution to a 50-year-old riddle: Why certain cells repel one another
When cells from the connective tissue collide, they repel one another -- this phenomenon was discovered more than 50 years ago. It is only now, however, that researchers at the University of Basel have discovered the molecular basis for this process, as they report in the journal Developmental Cell. Their findings could have important implications for cancer research.

Contact: Reto Caluori
University of Basel

Public Release: 1-Oct-2015
18th ECCO - 40th ESMO European Cancer Congress
Gene therapy doubles survival in recurrent glioblastoma
An experimental gene therapy essentially doubled the overall survival of patients with recurrent glioblastoma compared to the current standard of care, a researcher said Oct. 1 at the Cancer Therapy & Research Center at The University of Texas Health Science Center at San Antonio.

Contact: Will Sansom
University of Texas Health Science Center at San Antonio

Public Release: 1-Oct-2015
JAMA Oncology
Study finds gaps in clinical genetic counseling services for women undergoing BRCA testing
A University of South Florida-led research collaboration with Aetna, the American Cancer Society and the national non-profit Facing Our Risk of Cancer Empowered today published results from a national study identifying factors and outcomes associated with the use of genetic counseling and testing services for hereditary breast and ovarian cancer in the community setting. The work indicates a significant opportunity to increase genetic counseling in community care.
Aetna Foundation, USF, Facing Our Risk of Cancer Empowered, Inc (FORCE), American Cancer Society

Contact: Anne DeLotto Baier
University of South Florida (USF Health)

Public Release: 1-Oct-2015
Journal of the National Cancer Institute
Genes of colon cancer recurrence differs among blacks, whites and Asians, Mayo Clinic study finds
The genetic makeup of colon cancer tumors and survival rates for patients with the disease differ by race, according to a study from researchers at the Mayo Clinic Cancer Center, published in the Oct. 2015 issue of the Journal of the National Cancer Institute.

Contact: Joe Dangor
Mayo Clinic

Public Release: 1-Oct-2015
Annals of Thoracic Surgery
Lung cancer screening programs do not increase rates of unnecessary surgeries
Lung cancer screening programs that utilize standardized reporting and include cardiothoracic surgeons as part of a multidisciplinary team can successfully be adopted into clinical practice without an increase in surgical intervention for non-cancerous disease, according to an article in the October 2015 issue of The Annals of Thoracic Surgery.

Contact: Cassie McNulty
Elsevier Health Sciences

Public Release: 1-Oct-2015
Journal of National Cancer Institute
Rising cancer rates in low and middle income countries threaten economic stability
The rising cost of treating and caring for a growing number of cancer patients threatens economic development in low and middle income countries, making prevention key.
American Cancer Society, International Agency for Research on Cancer, Imperial College London

Contact: David Sampson
American Cancer Society

Public Release: 1-Oct-2015
Gynecologic Oncology
Preventing cancer: Study finds dramatic benefits of weight-loss surgery
A study evaluating the effects of bariatric surgery on obese women most at risk for cancer has found that the weight-loss surgery slashed participants' weight by one-third and eliminated precancerous uterine growths in those that had them.

Contact: Josh Barney
University of Virginia Health System

Public Release: 1-Oct-2015
Cancer Cell
Study shows new 'driver' to assess cancer patient survival and drug sensitivity
Cancer specialists have long looked at genetic mutations and DNA copy changes to help predict patient survival and drug sensitivity.

Contact: Ron Gilmore
University of Texas M. D. Anderson Cancer Center

Public Release: 30-Sep-2015
Journal of the National Cancer Institute
Doctors often overtreat with radiation in late-stage lung cancer
Almost half of patients with advanced lung cancer receive more than the recommended number of radiation treatments to reduce their pain, according to a new study published in the Journal of the National Cancer Institute.

Contact: Sharon Parmet
University of Illinois at Chicago

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