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Showing releases 1-25 out of 1365.

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Public Release: 29-Jun-2016
Cancer Epidemiology, Biomarkers & Prevention
Persistent HPV infection raises risk of anal and genital cancers
Women with a history of severe cervical intraepithelial neoplasia, a precancerous condition of the cervix that arises from infection with the human papillomavirus (HPV), had a long-term increased risk of developing anal, vulvar, and vaginal cancer.
Danish Cancer Society Research Center

Contact: Lauren Riley
American Association for Cancer Research

Public Release: 28-Jun-2016
Nature Communications
Researchers find protein signatures for accurate noninvasive diagnosis of prostate cancer
Researchers at the Ontario Institute for Cancer Research and University Health Network in Toronto, along with researchers at the Eastern Virginia Medical School, have created protein signatures that accurately diagnose prostate cancer and can distinguish between patients with aggressive versus non-aggressive disease using a simple urine sample.

Contact: Christopher Needles
Ontario Institute for Cancer Research

Public Release: 28-Jun-2016
International Journal of Cancer
Gene signature in ovarian cancer predicts survival and offers new drug target
A new UK study has identified a gene signature that predicts poor survival from ovarian cancer. The study also identified genes which help the cancer develop resistance to chemotherapy -- offering a new route to help tackle the disease.

Contact: Jenny Watkinson
University of Bradford

Public Release: 28-Jun-2016
Journal of Natural Products
Parsley and dill help fight cancer, research shows
A team of Russian scientists proposed an efficient approach to a novel agents with anticancer activity. A synthesis of these compounds is based on compounds extracted from parsley and dill seeds. The results of the study have been published in the Journal of Natural Products.

Contact: Matvey Kireev
Moscow Institute of Physics and Technology

Public Release: 28-Jun-2016
Nature Communications
Researchers use liquid biopsy biomarkers to identify prostate cancer before surgery
Prostate cancer researchers have discovered biomarkers using non-invasive liquid biopsies to identify aggressive disease before surgery.
The Canadian Institutes of Health Research, National Institutes of Health, Ontario Institute for Cancer Research, Ontario Ministry of Health and Long-term Care, The Princess Margaret Cancer Foundation

Contact: Jane Finlayson
University Health Network

Public Release: 28-Jun-2016
ACS Nano
A 2-in-1 punch for taking out cancer
Bioengineers at Brigham and Women's Hospital have engineered a single nanoparticle that comprises a synergistic drug pair and demonstrate that the mechanisms of resistance can be shut down to a degree that has never been achieved before.
US Department of Defense, National Institutes of Health, American Lung Association, Indo-US Joint Center, American Cancer Society

Contact: Haley Bridger
Brigham and Women's Hospital

Public Release: 28-Jun-2016
Journal of Thoracic Oncology
Lung cancer experts seek public comments on revised molecular testing guideline
The College of American Pathologists, the International Association for the Study of Lung Cancer, and the Association for Molecular Pathology announced today the open comment period for the revised evidence-based guideline, 'Molecular Testing Guideline for Selection of Lung Cancer Patients for EGFR and ALK Tyrosine Kinase Inhibitors.'

Contact: Jeffrey Wolf
International Association for the Study of Lung Cancer

Public Release: 28-Jun-2016
Risk of death for adults with blood cancer higher in three N.C. regions
For patients treated in a hospital, the risk of death from acute myeloid leukemia was elevated in three regions of North Carolina compared to a benchmark.

Contact: Laura Oleniacz
UNC Lineberger Comprehensive Cancer Center

Public Release: 27-Jun-2016
Journal of Archives and Lab Medicine and Pathology
Allina Health neuroscience study improves tumor subtyping
Pathology study leads to creation of an algorithm to save time and costs in making brain tumor diagnoses.
Abbott Northwestern Hospital Foundation and Allina Health Center for Healthcare Innovation

Contact: Gloria O'Connell
Allina Health

Public Release: 27-Jun-2016
Journal of Clinical Investigation
Researchers find a likely cause of inflammatory myofibroblastic tumors
Researchers at University of California San Diego School of Medicine have found that a likely cause of inflammatory myofibroblastic tumors is deficiency in nonsense-mediated RNA decay, a system cells use to control which genes are activated.
National Institutes of Health, YangFan Plan of Tongji University School of Medicine

Contact: Heather Buschman
University of California - San Diego

Public Release: 27-Jun-2016
Proceedings of the National Academy of Sciences
Researchers develop method to map cancer progression
A team of scientists has developed a computational method to map cancer progression, an advance that offers new insights into the factors that spur this affliction as well as new ways of selecting effective therapies.
National Science Foundation, Instituto de Salud Carlos III, European Regional Development Fund, Spanish Association Against Cancer Scientific Foundation, Catalan Government DURSI grant

Contact: James Devitt
New York University

Public Release: 27-Jun-2016
Nature Structural & Molecular Biology
TSRI scientists find new cancer drug target in dual-function protein
Scientists at The Scripps Research Institute have identified a protein that launches cancer growth and appears to contribute to higher mortality in breast cancer patients. The new findings suggest that future therapies might target this protein, called GlyRS, to halt cancer growth.
National Institutes of Health

Contact: Madeline McCurry-Schmidt
Scripps Research Institute

Public Release: 27-Jun-2016
Nature Biotechnology
Epigenetics: New tool for precision medicine
Four new papers, co-published by an international consortium of biomedical researchers, mark the feasibility of epigenetic analysis for clinical diagnostics and precision medicine. Epigenetic analysis addresses key limitations of genetic testing, helping to ensure that patients are accurately diagnosed and treated with the right drug at the right time.
BLUEPRINT Consortium

Contact: Wolfgang Däuble
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences

Public Release: 27-Jun-2016
Journal of Clinical Oncology
IU study finds testicular cancer survivors may have hearing loss after cisplatin therapy
Many testicular cancer survivors experience hearing loss after cisplatin-based chemotherapy, according to researchers at Indiana University.
National institutes of Health

Contact: Michael Schug
Indiana University

Public Release: 27-Jun-2016
Nature Communications
New insight into cancer genes could lead to personalized treatments
Research, involving scientists and doctors at the University of Southampton and Royal Bournemouth Hospital, has identified a network of genes that are likely to be shared by all patients who have chronic lymphocytic leukaemia (CLL).
Bloodwise and Bournemouth Leukemia Fund

Contact: Becky Attwood
University of Southampton

Public Release: 27-Jun-2016
Bacterial colonies in human body linked to presence of cancer in mouth and throat
In a sample study, researchers at Johns Hopkins say they have found an association between the makeup of an individual's microbiome and head and neck cancer, a finding that potentially advances the quest for faster and more accurate cancer diagnosis and therapy.
NIH/National Cancer Institute, NIH/National Institute of Dental and Craniofacial Research

Contact: Vanessa McMains
Johns Hopkins Medicine

Public Release: 27-Jun-2016
Journal of Clinical Oncology
UTSA researcher develops new, non-invasive method to wipe out cancerous tumors
Matthew Gdovin, an associate professor in the UTSA Department of Biology, has developed a newly patented method to kill cancer cells. His discovery, described in a new study in The Journal of Clinical Oncology, may tremendously help people with inoperable or hard-to-reach tumors, as well as young children stricken with cancer.

Contact: Joanna Carver
University of Texas at San Antonio

Public Release: 27-Jun-2016
Women with early stage breast cancer experience functional decline after treatment
In a study of older women with newly diagnosed stage I to III breast cancer, approximately one in five lost the ability to complete some of the basic tasks necessary for independent living within one year of initiating treatment. The study also found that a simple survey can help identify which women are at risk of such functional decline. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

Contact: Dawn Peters

Public Release: 27-Jun-2016
Nature Biotechnology
Improvements in epigenomic sequencing technologies could enhance cancer diagnostics
An international research collaboration led by UCL scientists has developed ways to improve the quality and accuracy of information harvested from epigenome sequencing datasets in two new research papers published jointly in Nature Biotechnology and Nature Communications today. According to the studies, epigenome sequencing technologies can allow for more comprehensive analysis of cancers -- a key component in the development of targeted approaches to combat cancer.

Contact: Wendy Russell
University College London

Public Release: 24-Jun-2016
Science Advances
Cross talk between hormone receptors has unexpected effects
Although the estrogen receptor is considered dominant in breast cancer, the progesterone receptor assumes control when both receptors are present and exposed to estrogens and progestins. Then, the progesterone receptor drives estrogen receptor activity. Treating tumor-bearing mice with an estrogen antagonist and a progestin antagonist caused rapid tumor regression.
The Virginia and D. K. Ludwig Fund for Cancer Research, National Health and Medical Research Council of Australia, Cancer Prevention and Research Institute of Texas, and DOD/Breast Cancer Research Program

Contact: John Easton
University of Chicago Medical Center

Public Release: 24-Jun-2016
Applied and Environmental Microbiology
Beneficial bacteria may protect breasts from cancer
Bacteria that have the potential to abet breast cancer are present in the breasts of cancer patients, while beneficial bacteria are more abundant in healthy breasts, where they may actually be protecting women from cancer, according to Gregor Reid, Ph.D., and his collaborators. These findings may lead ultimately to the use of probiotics to protect women against breast cancer.

Contact: Aleea Khan
American Society for Microbiology

Public Release: 24-Jun-2016
Scientific Reports
In mice, daughters of overweight dads have altered breast tissue, higher cancer risk
Obese male mice and normal weight female mice produce female pups that are overweight at birth through childhood, and have delayed development of their breast tissue as well as increased rates of breast cancer. The findings, published online June 24 in Scientific Reports by Georgetown Lombardi Comprehensive Cancer Center researchers, come from one of the first animal studies to examine the impact of paternal obesity on future generations' cancer risk.
American Cancer Society, Prevent Cancer Foundation

Contact: Karen Teber
Georgetown University Medical Center

Public Release: 24-Jun-2016
Genetic signatures expose drug susceptibility in breast cancer cells
A genomics approach at the Medical University of South Carolina has unmasked genetic signatures in breast cancer cells that predict their sensitivity to certain drugs. The findings, published in the May 2, 2016 issue of Oncotarget, provide proof of concept for personalized pharmaceutical therapies that target the genes responsible for driving tumor growth.
Genomics and Biostatistics Shared Resources, Hollings Cancer Center, Medical University of SouthCarolina, National Institutes of Health

Contact: Heather Woolwine
Medical University of South Carolina

Public Release: 24-Jun-2016
Journal of General Internal Medicine
UTSW research: Primary care visits result in more colon cancer screening, better followups
People who visit their primary care physicians are more likely to get potentially life-saving colon cancer screenings and follow up on abnormal stool blood test results -- even in health systems that heavily promote mail-in home stool blood tests that don't require a doctor visit, a study involving UT Southwestern population health researchers shows.

Contact: Lori Sundeen Soderbergh
UT Southwestern Medical Center

Public Release: 24-Jun-2016
Top story for cancer research
A team of researchers led by Dr. Friederike J. Gruhl and Professor Andrew C. B. Cato at Karlsruhe Institute of Technology (KIT) are developing a three-dimensional model for prostate cancer research based on cryogels. The model will be used to reproduce natural processes and above all to examine the development and the progression of tumors. A current paper on this project published in the scientific journal Small (DOI: 10.1002/smll.201600683).

Contact: Monika Landgraf
Karlsruher Institut für Technologie (KIT)

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