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Key: Meeting
Showing releases 1-25 out of 1207.
Public Release: 23-May-2013
 CellDiscarded immune cells induce the relocation of stem cells The study reveals a surprising coordination between two fundamental body systems, the immune and the hematopoietic. The study has implications for the understanding of metastasis, because malignant stem cells involved in tumor formation could take advantage of this mechanism. Contact: Ainhoa Iriberri
Public Release: 23-May-2013
Journal of Biological ChemistryUEA scientists make breast cancer advance that turns previous thinking on its head Scientists at the University of East Anglia have made an advance in breast cancer research which shows how some enzymes released by cancerous cells could have a protective function. 
Big C
Contact: University of East Anglia Press Office
Public Release: 23-May-2013
Cancer Epidemiology, Biomarkers & PreventionFrequent heartburn may predict cancers of the throat and vocal cord A frequent history of heartburn elevated risk for throat and vocal cord cancers. Use of antacids lowered risk. Further studies are needed to confirm the protective effect of antacids. Contact: Jeremy Moore
Public Release: 23-May-2013
Chemistry & BiologyNew screening approach uncovers potential alternative drug therapies for neuroblastoma Nearly two-thirds of patients with high-risk neuroblastoma -- a common tumor that forms in the nerve cells of children -- cannot be cured using tumor-killing cancer drugs. A study published in Chemistry & Biology reveals a new genomic approach to screen for compounds that inhibit tumor growth by causing cancer cells to differentiate. Using this screening method, the researchers identified a compound that causes neuroblastoma cells to differentiate, uncovering promising new treatment strategies. Contact: Mary Beth O'Leary
Public Release: 23-May-2013
Molecular CellResearch identifies a way to make cancer cells more responsive to chemotherapy Breast cancer characterized as "triple negative" carries a poor prognosis, with limited treatment options. In some cases, chemotherapy doesn't kill the cancer cells the way it's supposed to. New research from Western University's Dr. Shawn Li, Ph.D., explains why some cancer cells don't respond to chemotherapy, and identifies a mechanism to rectify that.
Canadian Cancer Society
Contact: Kathy Wallis
Public Release: 23-May-2013
Molecular CellProtein preps cells to survive stress of cancer growth and chemotherapy Scientists have uncovered a survival mechanism that occurs in breast cells that have just turned premalignant -- cells on the cusp between normalcy and cancers -- which may lead to new methods of stopping tumors. Contact: Andy Hoang
Public Release: 23-May-2013
BloodImproved chemo regimen for childhood leukemia may offer high survival, no added heart toxicity Treating pediatric leukemia patients with a liposomal formulation of anthracycline-based chemotherapy at a more intense-than-standard dose during initial treatment may result in high survival rates without causing any added heart toxicity, according to the results of a study published online today in Blood, the Journal of the American Society of Hematology. Contact: Amanda Szabo
Public Release: 23-May-2013
Cancer ResearchMayo Clinic genomic analysis lends insight to prostate cancer Mayo Clinic researchers have used next generation genomic analysis to determine that some of the more aggressive prostate cancer tumors have similar genetic origins, which may help in predicting cancer progression. The findings appear online today in the journal Cancer Research.
Waterman Biomarker Discovery
Contact: Bob Nellis
Public Release: 23-May-2013
ScienceAnti-cancer drug viewed as possible Alzheimer's treatment doesn't work in UF study An anti-cancer drug about to be tested in a clinical trial by a biomedical company in Ohio as a possible treatment for Alzheimer's disease has failed to work with the same type of brain plaques that plague Alzheimer's patients, according to results of a study by University of Florida researchers. Contact: Rossana Passaniti
Public Release: 23-May-2013
NatureWhen oxygen is short, EGFR prevents maturation of cancer-fighting miRNAs Even while being dragged to its destruction inside a cell, a cancer-promoting growth factor receptor fires away, sending signals that thwart the development of tumor-suppressing microRNAs before it's dissolved, researchers reported in an early online publication at Nature. Contact: Scott Merville
Public Release: 23-May-2013
Science SignalingUCI study reveals new mechanism for estrogen suppression of liver lipid synthesis By discovering the new mechanism by which estrogen suppresses lipid synthesis in the liver, UC Irvine endocrinologists have revealed a potential new approach toward treating certain liver diseases. With this finding, Dr. Ellis Levin and colleagues believe they are changing long-held views in the field.
National Institutes of Health, Department of Veterans Affairs
Contact: Tom Vasich
Public Release: 23-May-2013
CellScientists discover how rapamycin slows cell growth University of Montreal researchers have discovered a novel molecular mechanism that can potentially slow the progression of some cancers and other diseases of abnormal growth. In the May 23 edition of the prestigious journal Cell, scientists from the University of Montreal explain how they found that the anti-cancer and anti-proliferative drug rapamycin slows down or prevents cells from dividing.
Canadian Institutes of Health Research, Natural Sciences and Engineering Research Council of Canada
Contact: Julie Gazaille
Public Release: 22-May-2013
ACS Chemical BiologyOvercoming resistance to anti-cancer drugs by targeting cell 'powerhouses' Re-routing anti-cancer drugs to the "power plants" that make energy to keep cells alive is a promising but long-neglected approach to preventing emergence of the drug-resistant forms of cancer -- source of a serious medical problem, scientists are reporting. That's the conclusion of a new study published in the journal ACS Chemical Biology. Contact: Michael Bernstein
Public Release: 22-May-2013
Journal of Controlled ReleaseResearch offers promising new approach to treatment of lung cancer Researchers have developed a new drug delivery system that allows inhalation of chemotherapeutic drugs to help treat lung cancer, and in laboratory and animal tests it appears to reduce the systemic damage done to other organs while significantly improving the treatment of lung tumors -- the tumors virtually disappeared.
NIH/National Cancer Institute, National Science Foundation, Department of Defense
Contact: Oleh Taratula
Public Release: 22-May-2013
New England Journal of MedicineNLST: CT detects twice as many lung cancers as X-ray at initial screening exam Low-dose CT scans detected twice as many early-stage lung cancers as chest X-ray on initial screening exam, according to additional National Lung Screening Trial results. Investigators say the 20 percent lung cancer mortality reduction previously reported in the NLST is achievable at experienced screening centers in the United States.
National Cancer Institute
Contact: Shawn Farley
Public Release: 22-May-2013
Cell ReportsStudy details genes that control whether tumors adapt or die when faced with p53 activating drugs When turned on, the gene p53 turns off cancer. However, when existing drugs boost p53, only a few tumors die -- the rest resist the challenge. A study published in the journal Cell Reports shows how: tumors that live even in the face of p53 reactivation create more of the protein p21 than the protein PUMA; tumors that die have more PUMA than p21. And, for the first time, the current study shows a handful of genes that control this ratio. Contact: Garth Sundem
Public Release: 21-May-2013
Journal of Biological ChemistryMayo Clinic: How gold nanoparticles can help fight ovarian cancer Positively charged gold nanoparticles are usually toxic to cells, but cancer cells somehow manage to avoid nanoparticle toxicity. Mayo Clinic researchers found out why, and determined how to make the nanoparticles effective against ovarian cancer cells. Contact: Bob Nellis
Public Release: 21-May-2013
PLOS ONENew tumor-killer shows great promise in suppressing cancers Scientists from Nanyang Technological University and Lund University, Sweden, have bioengineered a novel molecule which has been proven to successfully kill tumor cells. Contact: Lester Kok
Public Release: 21-May-2013
I Iberian Conference on the Clinical Physiology of Health and Sport Tobacco ControlWarning images for cigarette packs proposed by Europe do not make enough emotional impact Not only are some of the images not perceived as negative -- people actually see them as positive. So, they could have the opposite effect by motivating people to approach the stimulus, that is, tobacco. Contact: Miguel Ángel Muñoz
Public Release: 21-May-2013
Nature CommunicationsUofL scientists uncover how grapefruits provide a secret weapon in medical drug delivery University of Louisville researchers have uncovered how to create nanoparticles using natural lipids derived from grapefruit, and have discovered how to use them as drug delivery vehicles.
National Institutes of Health, Louisville Veterans Administration Medical Center, Susan G. Komen Breast Cancer Foundation
Contact: Julie Heflin
Public Release: 21-May-2013
2013 ASCO Annual MeetingPoliovirus vaccine trial shows early promise for recurrent glioblastoma An attack on glioblastoma brain tumor cells that uses a modified poliovirus is showing encouraging results in an early study to establish the proper dose level, researchers at Duke Cancer Institute report. Contact: Sarah Avery
Public Release: 21-May-2013
Journal of the American Chemical SocietyUCI chemists devise inexpensive, accurate way to detect prostate cancer Early screening for prostate cancer could become as easy for men as personal pregnancy testing is for women, thanks to UC Irvine research published today in the Journal of the American Chemical Society. Contact: Janet Wilson
Public Release: 21-May-2013
Cancer DiscoveryChanging cancer's environment to halt its spread By studying the roles two proteins, thrombospondin-1 and prosaposin, play in discouraging cancer metastasis, a trans-Atlantic research team has identified a five-amino acid fragment of prosaposin that significantly reduces metastatic spread in mouse models of prostate, breast and lung cancer. The findings suggest that a prosaposin-based drug could potentially block metastasis in a variety of cancers.
NIH/National Cancer Institute, Norwegian Cancer Society, Norwegian Research Council, and others
Contact: Keri Stedman
Public Release: 21-May-2013
eLifeKeeping stem cells strong A team of researchers led by biologists at the California Institute of Technology has found that, in mouse models, the molecule microRNA-146a acts as a critical regulator and protector of blood-forming stem cells (called hematopoietic stem cells, or HSCs) during chronic inflammation, suggesting that a deficiency of miR-146a may be one important cause of blood cancers and bone marrow failure.
NIH/National Cancer Institute, NIH/National Institute of Allergy and Infectious Disease, NIH/National Heart, Lung, and Blood Institute
Contact: Deborah Williams-Hedges
Public Release: 21-May-2013
2013 City of Hope National Medical Center Immunology Division Seminar SeriesMU researchers develop radioactive nanoparticles that target cancer cells Researchers at the University of Missouri have found a way to create radioactive nanoparticles that target lymphoma tumor cells wherever they may be in the body. Contact: Nathan Hurst
Showing releases 1-25 out of 1207.
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