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Showing releases 101-125 out of 1239.

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Public Release: 8-Sep-2014
Developmental Cell
Popular cancer drug target implicated in cardiovascular defects
UNC School of Medicine researchers have discovered an unlikely relationship between CXCR7 -- a protein implicated in tumor growth and metastasis -- and adrenomedullin -- a hormone involved in cardiovascular health. Deleting CXCR7 allows adrenomedullin to run rampant, triggering the development of an enlarged heart and the overgrowth of the lymphatic vessels that traffic immune cells and fluids throughout the body.
National Institutes of Health, American Heart Association

Contact: Mark Derewicz
mark.derewicz@unchealth.unc.edu
919-923-0959
University of North Carolina Health Care

Public Release: 8-Sep-2014
European Respiratory Society International Congress
Breath temperature test could identify lung cancer
The temperature of exhaled breath could be used to diagnose lung cancer, according to a new study.

Contact: Lauren Anderson
lauren.anderson@europeanlung.org
142-672-876
European Lung Foundation

Public Release: 8-Sep-2014
Urologic Oncology
Watchful waiting isn't right for everyone
African American men are one population that may be harmed by new guidelines that favor observation over treatment of early-stage prostate cancer.

Contact: Edyta Zielinska
edyta.zielinska@jefferson.edu
215-955-5291
Thomas Jefferson University

Public Release: 8-Sep-2014
Cancer Cell
Notch1 and osteoblasts play role in bone cancer initiation
A new mouse model of osteogenic sarcoma, a potentially deadly form of bone cancer, shows that high levels of Notch1, a gene that helps determine cell fate, can drive osteoblasts, cells that normally lead to bone formation, to become cancerous, said researchers from Baylor College of Medicine in a report in the journal Cancer Cell.
National Institutes of Health, Cancer Prevention and Research Institute of Texas, NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development, Baylor College of Medicine, Cancer Fighters of Houston

Contact: Glenna Picton
picton@bcm.edu
713-798-4710
Baylor College of Medicine

Public Release: 8-Sep-2014
Oncotarget
Gobbling up poison: A method for killing colon cancer
A new immunotoxin works by getting shuttled into cancer cells, selectively destroying colon cancer, thanks to a quirk of biology.

Contact: Edyta Zielinska
edyta.zielinska@jefferson.edu
215-955-5291
Thomas Jefferson University

Public Release: 7-Sep-2014
54th ICAAC
New antifungal as effective as existing drugs with fewer adverse events
A newly developed antifungal, isavuconazole, is as effective as an existing drug, voriconazole, against invasive mold disease in cancer patients with less adverse effects, according to phase 3 clinical data presented at the 54th Interscience Conference on Antimicrobial Agents and Chemotherapy, an infectious disease meeting of the American Society for Microbiology.

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology

Public Release: 7-Sep-2014
Nature Immunology
Dynamic duo takes out the cellular trash
Salk scientists identify how immune cells use two critical receptors to clear dead cells from the body, pointing the way to new autoimmune and cancer therapies.

Contact: Salk Communications
press@salk.edu
Salk Institute

Public Release: 7-Sep-2014
Nature Genetics
Ultraviolet light-induced mutation drives many skin cancers, Stanford researchers find
A genetic mutation caused by ultraviolet light is likely the driving force behind millions of human skin cancers, according to researchers at the Stanford University School of Medicine.
National Institutes of Health, US Veterans Affairs Office of Research and Development

Contact: Krista Conger
kristac@stanford.edu
650-725-5371
Stanford University Medical Center

Public Release: 7-Sep-2014
PLOS ONE
61 percent fall in female genital warts due to free HPV vaccine
General practitioners in Australia are managing 61 percent less cases of genital warts among young women since the introduction of the national human papillomavirus vaccination program, a new study from the University of Sydney reveals.

Contact: Kobi Print
kobi.print@sydney.edu.au
61-481-012-729
University of Sydney

Public Release: 7-Sep-2014
PLOS ONE
Trial shows improved overall survival for patients with liver cancer not amenable to surgery
The mature results from a trial conducted by the Asia-Pacific Hepatocellular Carcinoma Trials Group led by the National Cancer Centre Singapore and Singapore General Hospital have shown that patients who suffer from inoperable advanced hepatocellular carcinoma may have a chance to live significantly longer by using a combined therapy.

Contact: Edwin Yong
yong.c.y@nccs.com.sg
65-623-69465
SingHealth

Public Release: 5-Sep-2014
Oncogene
Combination microRNA therapy shown to suppress non-small-cell lung cancer
New findings show that a combination of two microRNAs suppressed tumor growth in an an animal model of non-small-cell lung cancer.
American Cancer Society, National Institutes of Health, Cancer Prevention & Research Institute of Texas

Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center

Public Release: 5-Sep-2014
Cancer Epidemiology, Biomarkers & Prevention
Research finds no association between wearing a bra and breast cancer
A population-based case-control study found no association between bra wearing and increased breast cancer risk among postmenopausal women, according to research published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
NIH/National Cancer Institute

Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research

Public Release: 5-Sep-2014
Clinical Cancer Research
New blood test could offer more tailored treatment of ovarian cancer
Researchers from the University of Manchester and The Christie NHS Foundation Trust -- both part of Manchester Cancer Research Centre -- say the test could be developed and used in hospitals within the next few years.

Contact: Alison Barbuti
alison.barbuti@manchester.ac.uk
44-016-127-58383
University of Manchester

Public Release: 5-Sep-2014
Nature Communications
UT Southwestern researchers find new gene mutations for Wilms Tumor
Researchers at UT Southwestern Medical Center and the Gill Center for Cancer and Blood Disorders at Children's Medical Center, Dallas, have made significant progress in defining new genetic causes of Wilms tumor, a type of kidney cancer found only in children.

Contact: Lori Sundeen Soderbergh
lori.soderbergh@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center

Public Release: 5-Sep-2014
Breast Cancer Symposium 2014
Novel immunotherapy vaccine decreases recurrence in HER2 positive breast cancer patients
A new breast cancer vaccine candidate, GP2, provides further evidence of the potential of immunotherapy in preventing disease recurrence.

Contact: Laura Sussman
lsussman@mdanderson.org
713-745-2457
University of Texas M. D. Anderson Cancer Center

Public Release: 5-Sep-2014
Journal of Clinical Oncology
Breast cancer specialist reports advance in treatment of triple-negative breast cancer
William M. Sikov, M.D., in the Program in Women's Oncology at Women & Infants Hospital of Rhode Island served as study chair and lead author for a recently-published major national study that could lead to improvements in outcomes for women with triple-negative breast cancer, an aggressive form of the disease that disproportionately affects younger women.

Contact: Susan McDonald
slmcdonald@wihri.org
401-681-2816
Women & Infants Hospital

Public Release: 4-Sep-2014
Breast Cancer Symposium 2014
Disparities persist in early-stage breast cancer treatment, MD Anderson study finds
Despite its acceptance as standard of care for early stage breast cancer almost 25 years ago, barriers still exist that preclude patients from receiving breast conserving therapy, with some still opting for a mastectomy, according to research from The University of Texas MD Anderson Cancer Center.

Contact: Laura Sussman
lsussman@mdanderson.org
713-745-2457
University of Texas M. D. Anderson Cancer Center

Public Release: 4-Sep-2014
Nature Biotechnology
Most accurate measures of gene expression
RNA-sequencing data analysis method BitSeq developed by Academy Research Fellow Antti Honkela's, Univeristy of Helsinki, research group and University of Manchester researchers has been found to be the most accurate gene transcript expression estimation method in a large international assessment. The method is based on probabilistic modelling which can capture the uncertainty related to the measurements.

Contact: Antti Honkela
antti.honkela@hiit.fi
University of Helsinki

Public Release: 4-Sep-2014
Breast Cancer Symposium 2014
Breast conserving therapy shows survival benefit compared to mastectomy in early-stage patients
When factoring in what is now known about breast cancer biology and heterogeneity, breast conserving therapy may offer a greater survival benefit over mastectomy to women with early stage, hormone-receptor positive disease, according to research from The University of Texas MD Anderson Cancer Center.

Contact: Laura Sussman
lsussman@mdanderson.org
713-745-2457
University of Texas M. D. Anderson Cancer Center

Public Release: 4-Sep-2014
New England Journal of Medicine
Phase III FIRST (MM-020/IFM 07-01) trial of REVLIMID (lenalidomide) plus dexamethasone in newly diagnosed multiple myeloma patients who are not candidates for stem cell transplant published in New England Journal of Medicine
The study met the primary endpoint as a significant progression-free survival benefit was seen for patients treated with continuous REVLIMID plus dexamethasone compared with those treated with a standard of care.
Intergroupe Francophone du Myélome, Celgene

Contact: Celgene Corporation
media@celgene.com
908-673-2275
Celgene Corporation

Public Release: 4-Sep-2014
Nature Communications
Avian influenza virus isolated in harbor seals poses a threat to humans
A study led by St. Jude Children's Research Hospital scientists found the avian influenza A H3N8 virus that killed harbor seals along the New England coast can spread through respiratory droplets and poses a threat to humans. The research appears in the current issue of the scientific journal Nature Communications.
NIH/National Institutes of Allergy and Infectious Diseases US Geological Survey, American Lebanese Syrian Associated Charities

Contact: Carrie Strehlau
carrie.strehlau@stjude.org
901-595-2295
St. Jude Children's Research Hospital

Public Release: 4-Sep-2014
SingHealth Duke-NUS Scientific Congress 2014
Study reveals breast surgery as a definitive and safe treatment for elderly patients
A study conducted by National Cancer Centre Singapore has shown that age per se is not a contraindication to breast cancer surgery, and such surgeries may be safely performed for women aged 80 years and above. Led by Dr. Ong Kong Wee, Senior Consultant in the Division of Surgical Oncology, the team consists of Dr. Veronique Tan, Consultant, and Dr. Lee Chee Meng, Resident Doctor. The study explores the safety of breast cancer surgery in women aged 80 years and above.

Contact: Edwin Yong
Edwin.Yong.c.y@nccs.com.sg
65-623-69465
SingHealth

Public Release: 4-Sep-2014
International Conference of the American Thoracic Society
Chest
A minimally invasive, high-performance intervention for staging lung cancer
Endoscopic biopsy of lymph nodes between the two lungs (mediastinum) is a sensitive and accurate technique that can replace mediastinal surgery for staging lung cancer in patients with potentially resectable tumours.
Canadian Foundation for Innovation, Society of University Surgeons, Fonds de recherche en santé du Québec, Thoracic Surgery Research Foundation of Montreal

Contact: Benjamin Augereau
benjamin.augereau@umontreal.ca
514-343-6796
University of Montreal

Public Release: 4-Sep-2014
Immunity
Team identifies important regulators of immune cell response
In a collaborative study, scientists from the Florida campus of The Scripps Research Institute and the La Jolla Institute for Allergy and Immunology have developed a more effective method to determine how immune cells called T cells differentiate into specialized types of cells that help eradicate infected cells and assist other immune cells during infection.
National Institutes of Health, Frenchman's Creek Women for Cancer Research

Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute

Public Release: 4-Sep-2014
Breast Cancer Symposium 2014
2014 Breast Cancer Symposium highlights research advances in prevention, screening, therapy
Five studies from the 2014 Breast Cancer Symposium were highlighted today in an embargoed presscast for reporters. Presentations focused on new studies exploring preventive mastectomy, compliance with recommended screening mammography, and risk of recurrence after pre-surgery therapy for breast cancer. The Symposium will take place Sept. 4-6, 2014, at the San Francisco Marriott Marquis in San Francisco, CA.

Contact: Kate Blackburn
kate.blackburn@asco.org
571-483-1379
American Society of Clinical Oncology

Showing releases 101-125 out of 1239.

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