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Showing releases 101-125 out of 1264.

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Public Release: 16-Oct-2014
Cancer Cell
Human cancer prognosis is related to newly identified immune cell
A newly discovered population of immune cells in tumors is associated with less severe cancer outcomes in humans, and may have therapeutic potential, according to a new UC San Francisco study of 3,600 human tumors of 12 types, as well as mouse experiments.
National Institutes of Health

Contact: Jeffrey Norris
jeffrey.norris@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 16-Oct-2014
Journal of Experimental Medicine
Researchers develop personalized ovarian cancer vaccines
Researchers used new genomic analysis techniques to identify specific protein sequences, called epitopes, that the immune system can use to identify cancer cells. Their key insight was that the most effective epitopes to include in a personalized vaccine are not those that react most strongly with the immune system, but rather the epitopes that differ most from the host's normal tissue.
National Institutes of Health

Contact: Kim Krieger
kim.krieger@uconn.edu
860-486-0361
University of Connecticut

Public Release: 16-Oct-2014
Cell Reports
Pitt/McGowan Institute team discovers stem cells in the esophagus
Despite previous indications to the contrary, the esophagus does have its own pool of stem cells, said researchers from the University of Pittsburgh School of Medicine in an animal study published online today in Cell Reports. The findings could lead to new insights into the development and treatment of esophageal cancer and the precancerous condition known as Barrett's esophagus.
Commonwealth of Pennsylvania, National Institutes of Health, McGowan Institute of Regenerative Medicine, University of Pittsburgh Department of Pathology

Contact: Anita Srikameswaran
SrikamAV@upmc.edu
412-578-9193
University of Pittsburgh Schools of the Health Sciences

Public Release: 16-Oct-2014
Journal of the National Cancer Institute
A good diet before diagnosis is linked with lower mortality among OVCA survivors
Prediagnosis diet quality was associated with mortality and may have a protective effect after ovarian cancer, according to a new study published Oct. 14 in the JNCI: Journal of the National Cancer Institute.

Contact: Zachary Rathner
Zachary.Rathner@oup.com
919-677-2697
Oxford University Press USA

Public Release: 16-Oct-2014
Musculoskeletal Tumor Society (MSTS) 2014 Annual Meeting
Simple test may predict surgical wound healing complications
A simple test called transcutaneous oximetry may be able to predict which patients with soft tissue sarcomas will experience complications while healing from surgery, potentially enabling surgeons to take extra precautions, a study has found.

Contact: Jim Ritter
jritter@lumc.edu
708-216-2445
Loyola University Health System

Public Release: 16-Oct-2014
PLOS ONE
Modeling tumor dormancy
A new computational model developed in the laboratory of Salvatore Torquato, a Professor of Chemistry at Princeton University, may help illuminate the conditions surrounding tumor dormancy and the switch to a malignant state. Published today in PLOS ONE, the so-called cellular automaton model simulated various scenarios of tumor growth leading to tumor suppression, dormancy or proliferation.
NIH/National Cancer Institute

Contact: Tien Nguyen
tienn@princeton.edu
Princeton University

Public Release: 16-Oct-2014
Food Additives and Contaminants A
Some rice-based foods for people with celiac disease contain relevant amounts of arsenic
Rice is one of the few cereal grains consumed by people with celiac disease, as it does not contain gluten. However, it can have high concentrations of a toxic substance -- arsenic -- as revealed by the analyses of flour, cakes, bread, pasta and other foods made with rice, conducted by researchers from the Miguel Hernández University of Elche, Spain. The European Union is working to establish the maximum quantities of arsenic in these products.

Contact: SINC
info@agenciasinc.es
34-914-251-820
FECYT - Spanish Foundation for Science and Technology

Public Release: 15-Oct-2014
Gut
UK tops global league table for gullet cancer -- adenocarcinoma -- in men
The UK tops the international league table for a type of gullet (oesophageal) cancer, known as adenocarcinoma, in men, reveals a comprehensive estimate of the total number of new cases around the globe in 2012, and published online in the journal Gut. Worldwide, men are around four times as likely as women to develop the disease, the findings show.
World Cancer Research Fund

Contact: Emma Dickinson
edickinson@bmj.com
44-020-738-36529
BMJ-British Medical Journal

Public Release: 15-Oct-2014
BMJ
New test can help doctors choose best treatment for ovarian cancer
Researchers have devized a new test to help doctors diagnose ovarian tumors and choose the most appropriate treatment.
Flemish Government: Research Foundation-Flanders, Flanders' Agency for Innovation by Science and Technology, iMinds, National Institute for Health Research Imperial Biomedical Research Centre

Contact: Sam Wong
sam.wong@imperial.ac.uk
44-207-594-2198
Imperial College London

Public Release: 15-Oct-2014
Cancer Research
Two-faced gene: SIRT6 prevents some cancers but promotes sun-induced skin cancer
SIRT6 -- a protein that inhibits the growth of liver and colon cancers -- can promote the development of skin cancers by turning on an enzyme that increases inflammation, proliferation and survival of sun-damaged skin cells. This suggests that SIRT6 could provide a useful target for cancer prevention.
National Institutes of Health, American Cancer Society, University of Chicago Cancer Research Center

Contact: John Easton
john.easton@uchospitals.edu
773-795-5225
University of Chicago Medical Center

Public Release: 15-Oct-2014
Cancer Research
Prostate cancer's penchant for copper may be a fatal flaw
Like discriminating thieves, prostate cancer tumors scavenge and hoard copper that is an essential element in the body. But such avarice may be a fatal weakness.
National Institutes of Health

Contact: Sarah Avery
sarah.avery@duke.edu
919-660-1306
Duke University Medical Center

Public Release: 15-Oct-2014
JAMA Surgery
MD Anderson study first to compare treatments, survival benefits for early-stage lung cancer
Removal of the entire lobe of lung may offer patients with early-stage lung cancer better overall survival when compared with a partial resection, and stereotactic ablative radiotherapy may offer the same survival benefit as a lobectomy for some patients, according to a study from The University of Texas MD Anderson Cancer Center.

Contact: Laura Sussman
713-745-2457
University of Texas M. D. Anderson Cancer Center

Public Release: 15-Oct-2014
New England Journal of Medicine
NEJM Perspective: 'The FDA, e-cigarettes, and the demise of combusted tobacco'
In this NEJM Perspective, two Georgetown University professors explore the popularity of E-cigarettes and point out that they could lead to the 'demise' of cigarette smoking and save thousands of lives, but not until they are proven safe and are regulated by the US Food and Drug Administration.

Contact: Karen Teber
km463@georgetown.edu
Georgetown University Medical Center

Public Release: 15-Oct-2014
New England Journal of Medicine
Personalized cellular therapy achieves complete remission in 90 percent of acute lymphoblastic leukemia patients studied
Ninety percent of children and adults with acute lymphoblastic leukemia who had relapsed multiple times or failed to respond to standard therapies went into remission after receiving an investigational personalized cellular therapy, CTL019, developed at the Perelman School of Medicine at the University of Pennsylvania. The results are published this week in The New England Journal of Medicine.
National Institutes of Health, Leukemia and Lymphoma Society, Stand Up To Cancer-St. Baldrick's Pediatric Dream Team Translational Research Grant

Contact: Holly Auer
holly.auer@uphs.upenn.edu
215-200-2313
University of Pennsylvania School of Medicine

Public Release: 15-Oct-2014
American Society of Clinical Oncology
Subsidies help breast cancer patients adhere to hormone therapy
A federal prescription-subsidy program for low-income women on Medicare significantly improved their adherence to hormone therapy to prevent the recurrence of breast cancer after surgery.
American Cancer Society, National Institutes of Health

Contact: Sharon Parmet
sparmet@uic.edu
312-413-2695
University of Illinois at Chicago

Public Release: 15-Oct-2014
Journal of the American Academy of Dermatology
Ebola highlights disparity of disease burden in developed vs. developing countries
A recent study in Journal of the American Academy of Dermatology shows Ebola and other skin disease rates are hundreds of times higher in developing than in developed countries. The study highlights the need for disease monitoring even when the global burden of disease remains low.
Bill and Melinda Gates Foundation

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 15-Oct-2014
PLOS ONE
Cryptic clues drive new theory of bowel cancer development
Melbourne researchers have challenged conventional thinking on how the bowel lining develops and, in the process, suggested a new mechanism for how bowel cancer starts. The researchers produced evidence that stem cells are responsible for maintaining and regenerating the 'crypts' that are a feature of the bowel lining, and believe these stem cells are involved in bowel cancer development, a controversial finding as scientists are still divided on the stem cells' existence.
National Health and Medical Research Council, Victorian Government

Contact: Alan Gill
gill.a@wehi.edu.au
61-393-452-719
Walter and Eliza Hall Institute

Public Release: 15-Oct-2014
Current Biology
Novel mechanism affecting cell migration discovered
The GMF protein controls the size and lifetime of protrusions in migrating cells.
Academy of Finland

Contact: Minna Poukkula
minna.poukkula@helsinki.fi
University of Helsinki

Public Release: 15-Oct-2014
Proceedings of the National Academy of Sciences
Study reveals optimal particle size for anticancer nanomedicines
Nanomedicines consisting of nanoparticles for targeted drug delivery to specific tissues and cells offer new solutions for cancer diagnosis and therapy. In a recent study, researchers from the University of Illinois systematically evaluated the size-dependent biological profiles of three monodisperse drug-silica nanoconjugates to determine the optimum particle size for tissue penetration and tumor inhibition.

Contact: Jianjun Cheng
jianjunc@illinois.edu
217-244-3924
University of Illinois College of Engineering

Public Release: 15-Oct-2014
ACS Nano
Tuning light to kill deep cancer tumors
An international group of scientists led by Gang Han, Ph.D., at the University of Massachusetts Medical School, has combined a new type of nanoparticle with an FDA-approved photodynamic therapy to effectively kill deep-set cancer cells in vivo with minimal damage to surrounding tissue and fewer side effects than chemotherapy. This promising new treatment strategy could expand the current use of photodynamic therapies to access deep-set cancer tumors.

Contact: Jim Fessenden
james.fessenden@umassmed.edu
508-856-2688
University of Massachusetts Medical School

Public Release: 15-Oct-2014
Journal of Interferon & Cytokine Research
Pattern recognition receptors may be potent new drug targets for immune-mediated diseases
Chronic inflammation caused by activation of the human immune system contributes to a large and rapidly growing list of diseases including some cancers, cardiovascular disease, metabolic disorders, and autoimmune diseases. Significant advances in understanding the role that the cytokine-mediated JAK/STAT signaling network and pattern recognition receptors play in regulating immune responses and their potential as novel targets for developing potent new therapies are presented in a Review article in Journal of Interferon & Cytokine Research.

Contact: Kathryn Ryan
kryan@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 15-Oct-2014
Genes and Development
Key moment mapped in assembly of DNA-splitting molecular machine
Scientists reveal crucial steps and surprising structures in the genesis of the enzyme that divides the DNA double helix during cell replication.
National Institutes of Health, United Kingdom Medical Research Council

Contact: Justin Eure
jeure@bnl.gov
631-344-2347
DOE/Brookhaven National Laboratory

Public Release: 14-Oct-2014
New treatment target identified for aggressive breast cancer
One of the first-known oncogenes has a protein partner that helps breast cancer proliferate and when it's blocked, so is the cancer, scientists report.

Contact: Toni Baker
tbaker@gru.edu
706-721-4421
Medical College of Georgia at Georgia Regents University

Public Release: 14-Oct-2014
Stem Cell Reports
Stem cell discovery challenges dogma on how fetus develops; holds insights for liver cancer and reg
A Mount Sinai-led research team has discovered a new kind of stem cell that can become either a liver cell or a cell that lines liver blood vessels, according to a study published today in the journal Stem Cell Reports.
Black Family Stem Cell Institute, NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Greg Williams
newsmedia@mssm.edu
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 14-Oct-2014
New treatment designed to save more eyes from cancer
Doctors at Cincinnati Children's Hospital Medical Center have developed a new technique for treating the eye cancer retinoblastoma to improve the odds for preventing eye loss, blindness or death in children with advanced forms of the disease. The new procedure is credited saving the eyesight of a 4-year-old girl.

Contact: Nick Miller
nicholas.miller@cchmc.org
513-803-6035
Cincinnati Children's Hospital Medical Center

Showing releases 101-125 out of 1264.

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