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Showing releases 101-125 out of 1303.

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Public Release: 18-Aug-2015
American Chemical Society 250th National Meeting & Exposition
Powdered cranberry combats colon cancer in mice
Cranberries are often touted as a way to protect against urinary tract infections, but that may be just the beginning. Cranberry extracts reduced the size and number of colon tumors in mice, say researchers. Identifying the therapeutic molecules in the fruit could lead to a better understanding of its anti-cancer potential, they say. The team will describe their approach at the 250th National Meeting & Exposition of the American Chemical Society.

Contact: Michael Bernstein
American Chemical Society

Public Release: 18-Aug-2015
American Journal of Gastroenterology
Liver damage in hepatitis C patients significantly underestimated, says Henry Ford study
The number of hepatitis C patients suffering from advanced liver damage may be grossly underestimated and underdiagnosed, according to a study led by researchers at Henry Ford Health System and the US Centers for Disease Control and Prevention. The findings were the result of a study of nearly 10,000 patients suffering from hepatitis C, and could have a significant effect on patient care and healthcare policy regarding the chronic disease.

Contact: Tammy Battaglia
Henry Ford Health System

Public Release: 18-Aug-2015
Study compares heparin to warfarin for treatment of blood clots in patients with cancer
Among patients with active cancer and acute symptomatic venous thromboembolism (VTE; blood clots in the deep veins), the use of the low molecular-weight heparin tinzaparin daily for six months compared with warfarin did not significantly reduce recurrent VTE and was not associated with reductions in overall death or major bleeding, but was associated with a lower rate of clinically relevant nonmajor bleeding, according to a study in the Aug. 18 issue of JAMA.

Contact: Heather Amos
The JAMA Network Journals

Public Release: 18-Aug-2015
Journal of the National Cancer Institute
Nine-gene MPI can provide accurate survival stratification in patients with NSCLC
A nine-gene molecular prognostic index for patients with early-stage non-small cell lung cancer was able to provide accurate survival stratification and could potentially inform the use of adjuvant therapy in patients struggling with the disease, according to a study published Aug. 18 in the JNCI: Journal of the National Cancer Institute.

Contact: Zachary Rathner
Oxford University Press USA

Public Release: 18-Aug-2015
Nature Communications
MRI scanners can steer tumor busting viruses to specific target sites within the body
Scientists from the University of Sheffield have discovered MRI scanners, normally used to produce images, can steer cell-based, tumor busting therapies to specific target sites in the body.
Medical Research Council

Contact: Amy Pullan
University of Sheffield

Public Release: 18-Aug-2015
Lancet Oncology
Temple & Fox Chase Cancer Center testing drug for cancer & bone marrow disorders
Temple University Hospital and Fox Chase Cancer Center are the only two sites in Philadelphia that participated in an international phase I, randomized clinical trial which tested the drug guadecitabine (SGI-110) in Myelodysplastic syndromes (MDS) and acute myelogenous leukemia (AML). MDS are a group of bone marrow disorders in which the bone marrow doesn't produce enough healthy blood cells. AML is a cancer of the blood and bone marrow.

Contact: Jennifer Lee
Temple University Health System

Public Release: 17-Aug-2015
Nature Cell Biology
MD Anderson study reveals new insight into tumor progression
Scientists know that activation of growth factor receptors like epidermal growth factor receptors (EGFR) promote tumor progression in many types of cancer.

Contact: Ron Gilmore
University of Texas M. D. Anderson Cancer Center

Public Release: 17-Aug-2015
Journal of Clinical Oncology
Aspirin reverses obesity cancer risk
Research has shown that a regular dose of aspirin reduces the long-term risk of cancer in those who are overweight in an international study of people with a family history of the disease.
Medical Research Council, Cancer Research UK, European Union, Bayer Pharma

Contact: Helen Rae
University of Leeds

Public Release: 17-Aug-2015
Journal of Clinical Oncology
Drinking coffee daily may improve survival in colon cancer patients
Regular consumption of caffeinated coffee may help prevent the return of colon cancer after treatment and improve the chances of a cure, according to a new, large study from Dana-Farber Cancer Institute that reported this striking association for the first time.
NIH/National Cancer Institute, Pharmacia & Upjohn Company, Pfizer Oncology, National Institutes of Health

Contact: Anne Doerr
Dana-Farber Cancer Institute

Public Release: 17-Aug-2015
Journal of Clinical Oncology
Genetic test could improve blood cancer treatment
Testing for genetic risk factors could improve treatment for myeloma -- a cancer of the blood and bone marrow -- by helping doctors identify patients at risk of developing more aggressive disease. New research, published in the Journal of Clinical Oncology today (Monday), found as few as nine genetic features would need to be tested to identify high-risk patients who might benefit from intensive treatment.
Myeloma UK, Cancer Research UK, NIHR Biomedical Research Centre at The Royal Marsden NHS Foundation Trust, The Institute of Cancer Research

Contact: Claire Hastings
Institute of Cancer Research

Public Release: 17-Aug-2015
Journal of Clinical Oncology
Drinking coffee daily may improve survival in colon cancer patients
Regular consumption of caffeinated coffee may help prevent the return of colon cancer after treatment and improve the chances of a cure, according to a new, large study from Dana-Farber Cancer Institute that reported this striking association for the first time.
National Institutes of Health, Alliance for Clinical Trials in OncologyPharmacia, Upjohn Companythe National Cancer Institute

Contact: Anne Doerr
Dana-Farber Cancer Institute

Public Release: 17-Aug-2015
Proceedings of the National Academy of Sciences
'Jumping genes' unusually active in many gastrointestinal cancers, studies find
Results of a trio of studies done on human cancer tissue biopsies have added to growing evidence that a so-called jumping gene called LINE-1 is active during the development of many gastrointestinal cancers. The results suggest that these elements, formally known as transposons, might one day serve as a marker for early cancer diagnosis.
Sol Goldman Pancreatic Cancer Research Center, Fred and Janet Sanfilippo Fund in the Department of Pathology at the Johns Hopkins University School of Medicine, Burroughs Wellcome Fund Career Award for Biomedical Scientists Program

Contact: Catherine Gara
Johns Hopkins Medicine

Public Release: 17-Aug-2015
Journal of Clinical Oncology
First-of-its-kind study finds music therapy lowers anxiety during surgical breast biopsies
A first-of-its-kind study published in the Journal of Clinical Oncology finds that music therapy lessened anxiety for women undergoing surgical breast biopsies for cancer diagnosis and treatment. The two-year study out of University Hospitals Seidman Cancer Center involved 207 patients.
Kulas Foundation

Contact: George Stamatis
University Hospitals Case Medical Center

Public Release: 17-Aug-2015
Study reveals effects of chemoradiation in brains of glioblastoma patients
A study from Massachusetts General Hospital Cancer Center researchers -- the first to examine the effects of combined radiation and chemotherapy on the healthy brain tissue of glioblastoma patients -- reveals not only specific structural changes within patients' brains but also that the effect of cancer therapy on the normal brain appears to be progressive and continues even after radiation therapy has ceased.
NIH/National Cancer Institute, American Cancer Society

Contact: Katie Marquedant
Massachusetts General Hospital

Public Release: 17-Aug-2015
Tobacco Control
Smoking cessation drug not boosting number of smokers who quit
The introduction of a new prescription smoking-cessation aid, varenicline, in 2006 has had no significant impact on the rate at which Americans age 18 and older successfully quit smoking, according to a study led by researchers at University of California, San Diego School of Medicine.
NIH/National Cancer Institute under the State and Community Tobacco Control Initiative

Contact: Scott LaFee
University of California - San Diego

Public Release: 14-Aug-2015
Nature Communications
The protein that keeps cells static is found to play a key role in cell movement
The protein E-Cadherin is a kind of adhesive that keeps cells tightly bound together, thus favouring the organisation of tissues and organs. Scientists at the Institute for Research in Biomedicine now reveal a new function for E-Cad, one that contrasts with its accepted role in impeding cell movement. The researchers have published an article in Nature Communications in which they report that this protein is crucial for the coordinated movement of diverse cell types.

Contact: Sònia Armengou
Institute for Research in Biomedicine (IRB Barcelona)

Public Release: 14-Aug-2015
Science Advances
Revealed -- Helicobacter pylori's secret weapon
Is the game up for Helicobactor pylori? Researchers in the School of Pharmacy, at The University of Nottingham and AstraZeneca R&D have identified the molecular mechanism that the bacterium's best-known adhesion protein uses to attach to stomach sugars and evade the body's attempts to 'flush' it away.
EPSRC and AstraZeneca Centre for Doctoral Training in Targeted Therapeutics

Contact: Lindsay Brooke
University of Nottingham

Public Release: 14-Aug-2015
European Journal of Epidemiology
No link found between PTSD and cancer risk
In the largest study to date that examines Post Traumatic Stress Disorder as a risk factor for cancer, researchers from Boston University School of Medicine, have shown no evidence of an association.

Contact: Gina DiGravio
Boston University Medical Center

Public Release: 14-Aug-2015
Novel diagnostic tool for ethnically diverse non-small-cell lung cancer patients
Early-stage Non-small-cell Lung Cancer is asymptomatic and difficult to detect since no blood test for NSCLC is currently available. In a new study, Chen-Yu Zhang and Chunni Zhang's group at Nanjing Advanced Institute for Life Sciences, Nanjing University identified a panel of five serum microRNAs as the potential biomarker for NSCLC diagnosis. The study is published this week in the journal EBioMedicine.
National Basic Research Program of China (973 Program), Research Special Fund for Public Welfare Industry of Health of China, National Natural Science Foundation of China

Contact: Xi Chen
Nanjing University School of Life Sciences

Public Release: 14-Aug-2015
Newly discovered cells restore liver damage in mice without cancer risk
The liver is unique among organs in its ability to regenerate after being damaged. Exactly how it repairs itself remained a mystery until recently, when researchers supported by the National Institutes of Health discovered a type of cell in mice essential to the process. The researchers also found similar cells in humans.
NIH/National Institute of Environmental Health Sciences

Contact: Virginia Guidry
NIH/National Institute of Environmental Health Sciences

Public Release: 13-Aug-2015
International Journal of Obesity
Heavy smokers and smokers who are obese gain more weight after quitting
For smokers, the number of cigarettes smoked per day and current body mass index are predictive of changes in weight after quitting smoking, according to researchers at Penn State College of Medicine.
Penn State Hershey Cancer Institute

Contact: Matt Solovey
Penn State

Public Release: 13-Aug-2015
Journal of Investigative Dermatology
Transplant recipients more likely to develop aggressive melanoma
Organ transplant recipients are twice as likely to develop melanoma as people who do not undergo a transplant, and three times more likely to die of the dangerous skin cancer, suggests new research led by a Johns Hopkins Bloomberg School of Public Health student.
NIH/National Cancer Institute

Contact: Stephanie Desmon
Johns Hopkins University Bloomberg School of Public Health

Public Release: 13-Aug-2015
Nanomedicine: Nanotechnology, Biology, and Medicine
Advance in photodynamic therapy offers new approach to ovarian cancer
Researchers have made a significant advance in the use of photodynamic therapy to combat ovarian cancer in laboratory animals, using a combination of techniques that achieved complete cancer cell elimination with no regrowth of tumors.
Medical Research Foundation of Oregon

Contact: Oleh Taratula
Oregon State University

Public Release: 13-Aug-2015
A better way to personalize bladder cancer treatments
Researchers at UC Davis, in collaboration with colleagues at Jackson Laboratory, have developed a new way to personalize treatments for aggressive bladder cancer. In early proof-of-concept research, the team took bladder tumors from individual patients, identified actionable mutations and grafted the tumors into mice.
Veteran Administration, NIH/National Cancer Institute, The Laney Foundation

Contact: Carole Gan
University of California - Davis Health System

Public Release: 13-Aug-2015
JAMA Oncology
Mayo Clinic-led study validates tool for pt. reporting side effects in cancer clinical trials
A multicenter study involving Mayo Clinic researchers has found that the National Cancer Institute's Patient Reported Outcomes version of the Common Terminology Criteria for Adverse Events, was accurate, reliable and responsive, compared to other, established patient-reported and clinical measures. The study is published today in the journal JAMA Oncology.
NIH/National Cancer Institute

Contact: Jim McVeigh
Mayo Clinic

Showing releases 101-125 out of 1303.

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