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Showing releases 101-125 out of 1332.

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Public Release: 16-Apr-2015
Cell Reports
Study reveals possible new avenues for breast cancer therapy
An exhaustive analysis has been conducted of more than 12,000 distinct proteins present in an often aggressive and difficult to treat form of breast cancer, called triple-negative breast cancer. The results may help explain why these cancers often fail to respond to current drug treatments and may provide researchers with new targets for drug therapy. The types of proteins found in various subtypes of this aggressive cancer may suggest why they behave differently and respond to treatment differently.
NIH/National Cancer Institute, National Science Foundation, South Sound CARE Foundation, Washington Research Foundation, Gary E. Milgard Family Foundation

Contact: Leila Gray
leilag@uw.edu
206-685-0381
University of Washington Health Sciences/UW Medicine

Public Release: 16-Apr-2015
Journal of the National Cancer Institute
Cancer-related PTS linked to very limited cognitive impairment among newly diagnosed breast cancer patients
Cancer-related post-traumatic stress is associated with very limited cognitive impairment before treatment among newly diagnosed breast cancer patients, according to a new study published April 16 in the JNCI: Journal of the National Cancer Institute.

Contact: Zachary Rathner
Zachary.Rathner@oup.com
919-677-2697
Oxford University Press USA

Public Release: 16-Apr-2015
Journal of Cancer Survivorship
After prostate cancer, start walking
Walking at an easy pace for about three hours every week may be just enough physical activity to help prostate cancer survivors reduce damaging side effects of their treatment, according to a new Northwestern Medicine study.
NIH/National Cancer Institute, University of California San Francisco Research Evaluation and Allocation Committee Award

Contact: Erin Spain
spain@northwestern.edu
847-491-4888
Northwestern University

Public Release: 16-Apr-2015
American Journal of Public Health
Smokers who use e-cigarettes less likely to quit
The increase in use of e-cigarettes has led to heated debates between opponents who question the safety of these devices and proponents who claim the battery-operated products are a useful cessation tool. In a new study, University of California, San Diego School of Medicine researchers found that smokers who used e-cigarettes were 49 percent less likely to decrease cigarette use and 59 percent less likely to quit smoking compared to smokers who never used e-cigarettes.
California Department of Public Health

Contact: Yadira Galindo
ygalindo@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 16-Apr-2015
Science
Cell type responsible for scarring, skin-cancer growth identified by Stanford scientists
A skin cell responsible for scarring, and a molecule that inhibits the cell's activity, have been identified by researchers at the Stanford University School of Medicine.
National Institutes of Health, California Institute for Regenerative Medicine, Smith Family Trust, Hagey Laboratory for Pediatric Regenerative Medicine, Oak Foundation, Ingrid Lai and Bill Shu, Gunn/Olivier Fund, Human Frontier Science Program, and others

Contact: Krista Conger
kristac@stanford.edu
650-725-5371
Stanford University Medical Center

Public Release: 16-Apr-2015
JAMA Oncology
More analysis from the women's health initiative on hormones, breast cancer
Analysis of the longer-term influence of menopausal hormone therapy on breast cancer incidence in two Women's Health Initiative clinical trials suggests a pattern of changing influences over time on breast cancer, according to an article published online by JAMA Oncology.

Contact: Laura Mecoy
Lmecoy@labiomed.org
310-546-5860
The JAMA Network Journals

Public Release: 16-Apr-2015
Science
Scientists discover protein that boosts immunity to viruses and cancer
Scientists have discovered a protein that plays a central role in promoting immunity to viruses and cancer, opening the door to new therapies.
Medical Research Council, Wellcome Trust, British Heart Foundation

Contact: Sam Wong
sam.wong@imperial.ac.uk
44-207-594-2198
Imperial College London

Public Release: 16-Apr-2015
JAMA Oncology
Obesity significantly increases prostate cancer risk in African-American men, study finds
Obesity in black men substantially increases the risk of low- and high-grade prostate cancer, while obesity in white men moderately reduces the risk of low-grade cancer and only slightly increases the risk of high-grade cancer, according to the first large, prospective study to examine how race and obesity jointly affect prostate cancer risk.
NIH/National Cancer Institute, NIH/National Center for Complementary and Alternative Medicine, National Institutes of Health

Contact: Kristen Woodward
kwoodwar@fredhutch.org
206-667-5095
Fred Hutchinson Cancer Research Center

Public Release: 16-Apr-2015
JAMA Oncology
Obesity associated with prostate cancer risk in African-American men
Obesity was associated with an increased risk for prostate cancer in African-American men and that risk grew by nearly four times as body mass index increased, according to an article published online by JAMA Oncology.

Contact: Kristen Woodward
kwoodwar@fredhutch.org
206-667-5095
The JAMA Network Journals

Public Release: 15-Apr-2015
Science Translational Medicine
Tumor-only genetic sequencing may misguide cancer treatment in nearly half of all patients
A study by Johns Hopkins scientists strongly suggests that sequencing tumor genomes for clues to genetic changes might misdirect treatment in nearly half of all patients unless it is compared first to a genetic readout of their noncancerous tissue.
Dr. Miriam and Sheldon G. Adelson Medical Research Foundation, Commonwealth Foundation, American Association for Cancer Research's Stand Up To Cancer-Dream Team Translational Cancer Research Grant, John G. Ballenger Trust, and others

Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medicine

Public Release: 15-Apr-2015
Journal of Ovarian Research
Ovarian cancer: Genetic testing should be accessible to all women with the disease
Recent media attention has focused on American actress Angelina Jolie's decision to have her ovaries and fallopian tubes surgically removed after genetic testing for such cancers. A study led by a team from the Research Institute of the McGill University Health Center suggests that all women with ovarian cancer should be tested for these genes, regardless of their family history. The findings have clinical implications both for the treatment of this disease and for the screening of individuals at-risk.
Cancer Research Society and in part by funding from the Fonds de recherche du Québec-Santé, RI-MUHC, McGill's Faculty of Medicine, Ovarian Cancer Canada, and the Canadian Institutes of Health Research.

Contact: Julie Robert
julie.robert@muhc.mcgill.ca
514-934-1934 x71381
McGill University Health Centre

Public Release: 15-Apr-2015
Metabolomics
New blood test can predict future breast cancer
By analyzing a simple blood sample, scientists from the University of Copenhagen have succeeded in predicting if a woman will get breast cancer within two to five years. The method -- a metabolic blood profile -- is still in the early stages but over time the scientists expect it could be used to predict breast cancer and more generally to predict chronic disease.
Villum Foundation

Contact: Lene Hundborg Koss
lene.h.koss@food.ku.dk
Faculty of Science - University of Copenhagen

Public Release: 15-Apr-2015
Science Translational Medicine
Personal genome diagnostics study shows limitations of tumor-only sequencing for cancer
An 815-patient study from Personal Genome Diagnostics and Johns Hopkins shows that almost half of the genetic alterations identified using tumor-only sequencing are not actually associated with the patient's cancer, but instead are 'false positives' reflecting inherited mutations found in normal cells. Personalized medicine tailors treatments to the specific genetic makeup of the tumor, so this high rate of false positives has implications for the accuracy of targeted approaches if they rely on tumor-only sequencing.

Contact: Barbara Lindheim
blindheim@bllbiopartners.com
917-355-9234
BLL Partners, LLC

Public Release: 15-Apr-2015
Pigment Cell & Melanoma Research
Protein finding can pave the way for improved treatment of malignant melanoma
Researchers from Aarhus University have for the first time linked a new protein with malignant melanomas. The protein is detected in aggressive malignant melanoma cells and might be used to predict whether and how the cancer will spread. At the same time, the discovery also opens new doors for future improved treatment of patients with melanomas.

Contact: Mette Madsen
mette@biomed.au.dk
45-28-99-21-37
Aarhus University

Public Release: 15-Apr-2015
PLOS ONE
New method increases accuracy of ovarian cancer prognosis and diagnosis
University of Utah scientists have uncovered patterns of DNA anomalies that predict a woman's outcome significantly better than tumor stage. In addition, these patterns are the first known indicator of how well a woman will respond to platinum therapy. Published in the journal PLOS ONE, the patterns were discovered by using a new mathematical technique in the analysis of DNA profiles from the Cancer Genome Atlas, a national database containing data from hundreds of ovarian cancer patients.
Utah Science, Technology, and Research Initiative, NIH/National Human Genome Research Institute, National Science Foundation

Contact: Julie Kiefer
jkiefer@neuro.utah.edu
801-597-4258
University of Utah Health Sciences

Public Release: 15-Apr-2015
Frontiers in Public Health
Racial disparity in cancer mortality is narrowing, suggests new study
Cancer mortality remains significantly elevated among African-Americans. Between 2000 and 2010, overall mortality from cancer decreased faster among African-American women and men than among Caucasians. If current trends continue, racial disparities in cancer outcomes are expected to narrow further and might disappear over time.

Contact: Michiel Dijkstra
press@frontiersin.org
Frontiers

Public Release: 15-Apr-2015
Nature
New genomic research amends earlier triple negative breast cancer finding
Weill Cornell Medical College investigators tried to validate a previously reported molecular finding on triple negative breast cancer that many hoped would lead to targeted treatments for the aggressive disease. Instead, they discovered that the findings were limited to a single patient and could not be applied to further clinical work. This discovery, published April 15 in Nature, amends the earlier work and underscores the importance of independent study validation and careful assay development.

Contact: Jen Gundersen
jeg2034@med.cornell.edu
646-317-7402
Weill Cornell Medical College

Public Release: 15-Apr-2015
Journal of Clinical Oncology
Early use of palliative care in cancer improves patients' lives, outcomes for caregivers
A new randomized clinical trial with Dartmouth investigators has noted significant improvement in several measures among those who began palliative care early.
NIH/National Institute for Nursing Research, NIH/National Cancer Institute, NIH/National Center for Advancing Translational Sciences, Norris Cotton Cancer Center, American Cancer Society

Contact: Kirk Cassels
kirk.A.Cassels@Hitchcock.org
603-653-6177
The Geisel School of Medicine at Dartmouth

Public Release: 15-Apr-2015
ASTRO praises bipartisan Congress and President for passage of legislation to permanently fix SGR
The American Society for Radiation Oncology applauds the House of Representatives, the Senate and the President for milestone passage last night of the 'Medicare Access and CHIP Reauthorization Act' (H.R. 2) that permanently repeals the sustainable growth rate (SGR) formula, which has plagued the nation's health care infrastructure for more than a decade.

Contact: Michelle Kirkwood
michellek@astro.org
703-286-1600
American Society for Radiation Oncology

Public Release: 15-Apr-2015
Nature
Big data key to precision medicine's success
Technological advances are enabling scientists to sequence the genomes of cancer tumors, revealing a detailed portrait of genetic mutations that drive these diseases. But genomic studies are only one piece of the puzzle that is precision medicine, a Weill Cornell Medical College researcher writes in Nature.

Contact: Jen Gundersen
jeg2034@med.cornell.edu
646-317-7402
Weill Cornell Medical College

Public Release: 15-Apr-2015
Annals of Thoracic Surgery
New '4-D' lung cancer model could quicken discoveries
Researchers at Houston Methodist have invented a new, ex vivo lung cancer model that mimics the process of tumor progression. Tests of the model are published this month in the Annals of Thoracic Surgery, now online.
American Association for Thoracic Surgery, Graham Research Foundation, Houston Methodist Foundation, National Institutes of Health, Cancer Research & Prevention Institute of Texas

Contact: David Bricker
dmbricker@houstonmethodist.org
832-667-5811
Houston Methodist

Public Release: 15-Apr-2015
ecancermedicalscience
Anti-fungal drug shows promise as potential new cancer treatment
A common anti-fungal treatment has joined the ranks of drugs that may be suitable for use in treating cancer, according to research from the Repurposing Drugs in Oncology project published in ecancermedicalscience.

Contact: Audrey Nailor
audrey@ecancer.org
44-011-790-94608
ecancermedicalscience

Public Release: 15-Apr-2015
Journal of Oncology Navigation & Survivorship
GW Cancer Institute publishes core competencies for oncology patient navigators
The George Washington University Cancer Institute has finalized 45 core competency statements for oncology patient navigators, published in the Journal of Oncology Navigation and Survivorship.

Contact: Lisa Anderson
lisama2@gwu.edu
202-994-3121
George Washington University

Public Release: 15-Apr-2015
Annals of Oncology
Potential for prediction of progression for early form of breast cancer
Scientists in Manchester have identified a way to potentially predict which patients with an early form of breast cancer will experience disease progression.

Contact: Jamie Brown
jamie.brown@manchester.ac.uk
44-016-127-58383
University of Manchester

Public Release: 14-Apr-2015
Nanomedicine: Nanotechnology, Biology, and Medicine
Nanoparticles at specific temperature stimulate antitumor response
Seeking a way to stimulate antitumor responses via the immune system, Dartmouth researchers have identified the precise temperature that results in a distinct body-wide antitumor immune response that resists metastatic disease.
Dartmouth University, National Institutes of Health, Center for Molecular, Cellular, and Translational Immunological Research, Norris Cotton Cancer Center

Contact: Kirk Cassels
kirk.A.Cassels@Hitchcock.org
603-653-6177
The Geisel School of Medicine at Dartmouth

Showing releases 101-125 out of 1332.

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