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Showing releases 101-125 out of 1136.

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Public Release: 14-Nov-2012
Cancer Research
Research breakthrough could halt melanoma metastasis
In laboratory experiments, scientists have eliminated metastasis, the spread of cancer from the original tumor to other parts of the body, in melanoma by inhibiting a protein known as melanoma differentiation associated gene-9 (mda-9)/syntenin.

Contact: John Wallace
wallacej@vcu.edu
804-628-1550
Virginia Commonwealth University

Public Release: 14-Nov-2012
International Journal of Innovative Computing and Applications
Enhancing breast cancer detection
Straightforward imaging with an infrared, thermal, camera for detecting breast cancer early without the discomfort or inconvenience of mammography or biomolecular tests, according to a study to be published in the International Journal of Innovative Computing and Applications.

Contact: Albert Ang
press@inderscience.com
Inderscience Publishers

Public Release: 14-Nov-2012
Molecular Therapy
Cancer therapy -- Nanokey opens tumors to attack
There are plenty of effective anticancer agents around. The problem is that, very often, they cannot gain access to all the cells in solid tumors. A new gene delivery vehicle may provide a way of making tracks to the heart of the target.

Contact: Kathrin Bilgeri
kathrin.bilgeri@lmu.de
49-892-189-6938
Ludwig-Maximilians-Universität München

Public Release: 14-Nov-2012
Journal of the American College of Cardiology
Heart failure in older breast cancer patients linked to medication
Heart failure is a relatively common complication in older women with breast cancer, but the risk is even higher in those patients treated with adjuvant trastuzumab, Yale School of Medicine researchers report in the current issue of the Journal of the American College of Cardiology.
American Heart Association, Agency for Healthcare Research and Quality

Contact: Karen N. Peart
karen.peart@yale.edu
203-432-1326
Yale University

Public Release: 14-Nov-2012
RNA: Publication of the RNA Society
Rare parasitic fungi could have anti-flammatory benefits
Scientists at The University of Nottingham have discovered that a rare parasitic fungus that lives on hibernating caterpillars in Tibet could have a role to play in anti-inflammatory drugs for conditions such as asthma.
Biotechnology and Biological Sciences Research Council

Contact: Lindsay Brooke
lindsay.brooke@nottingham.ac.uk
44-011-595-15751
University of Nottingham

Public Release: 13-Nov-2012
PLOS ONE
A sip of resveratrol and a full p53: Ingredients for a successful cell death
Researchers at the Universidade Federal in Rio de Janeiro in Brazil have found that introduction of a normal copy of the p53 gene in p53-defective cancer cell lines makes these cells sensitive to the anti-tumor proprieties of resveratrol, the naturally occurring dietary compound found in red wine.
National Council for Scientific and Technological Development, Rio de Janeiro State Foundation for Research, Ministry of Health, Cancer Foundation, National Institute of Science and Technology for Structural Biol

Contact: Jerson Lima Silva
jerson@bioqmed.ufrj.br
55-212-562-6756
Publicase Comunicação Científica

Public Release: 13-Nov-2012
Carcinogenesis
Scientists discover how stomach cancer spreads
Scientists at the University of Liverpool have found that the production of a protein that prevents the growth and spread of cancerous cells is impaired in patients with gastric cancer.
National Institutes of Health, North West Cancer Research

Contact: Samantha Martin
samantha.martin@liv.ac.uk
44-015-179-42248
University of Liverpool

Public Release: 13-Nov-2012
Radiology
Stereoscopic mammography could reduce recall rate
A new three-dimensional digital mammography technique has the potential to significantly improve the accuracy of breast cancer screening.

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America

Public Release: 13-Nov-2012
International Scientific Forum on Alcohol Research
Effects of alcohol on lymphoma, leukemia, and other types of hematological cancers
Diseases associated with the lymphatic system can be separated from those of the myeloid system.

Contact: Helena Conibear
helena@alcohol-forum4profs.org
44-130-032-0869
Boston University Medical Center

Public Release: 13-Nov-2012
Cochrane Database of Systematic Reviews
Cancer: Exercise reduces tiredness
Aerobic exercise can help relieve the fatigue often associated with cancer and cancer treatment, according to Cochrane researchers. Their updated systematic review strengthens findings from an earlier version on cancer-related fatigue published in the Cochrane Library

Contact: Ben Norman
Sciencenewsroom@wiley.com
44-012-437-70375
Wiley

Public Release: 13-Nov-2012
Journal of Clinical Oncology
Terminally ill cancer patients who discuss end-of-life care early can avoid aggressive treatment
Terminally ill cancer patients who have an early talk with their physician about care at the end-of-life are less likely to receive aggressive therapy – and more likely to enter hospice care – than patients who delay such discussions until the days and weeks before death, a new study by Dana-Farber Cancer Institute researchers suggests.
NIH/National Cancer Institute, US Department of Veterans Affairs, American Cancer Society, and others

Contact: Anne Doerr
anne_doerr@dfci.harvard.edu
617-632-5665
Dana-Farber Cancer Institute

Public Release: 13-Nov-2012
Cancer Biotherapy and Radiopharmaceuticals
Can the addition of radiolabeled treatments improve outcomes in advanced metastatic disease?
Radiolabeled agents are powerful tools for targeting and killing cancer cells and may help improve outcomes and lengthen survival times of patients with advanced disease that has spread beyond the initial tumor site.

Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2100 x2156
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 13-Nov-2012
Oncology Nursing Forum
Ancient foot massage technique may ease cancer symptoms
A study led by a Michigan State University researcher offers the strongest evidence yet that reflexology – a type of specialized foot massage practiced since the age of pharaohs – can help cancer patients manage their symptoms and perform daily tasks.
NIH/National Cancer Institute

Contact: Andy McGlashen
andy.mcglashen@cabs.msu.edu
517-355-5158
Michigan State University

Public Release: 13-Nov-2012
Proceedings of the National Academy of Sciences
Injectable sponge delivers drugs, cells, and structure
Bioengineers at Harvard have developed a gel-based sponge that can be molded to any shape, loaded with drugs or stem cells, compressed to a fraction of its size, and delivered via injection. Once inside the body, it pops back to its original shape and gradually releases its cargo, before safely degrading.
National Institutes of Health, Wyss Institute, Juvenile Diabetes Research Foundation

Contact: Caroline Perry
cperry@seas.harvard.edu
617-496-1351
Harvard University

Public Release: 13-Nov-2012
Oncogene
For brain tumors, origins matter
Since stem cells and progenitor cells are regulated by different growth factors, brain tumors arising from these cells might respond differently to different therapies. Researchers at Sanford-Burnham Medical Research Institute found that basic fibroblast growth factor (bFGF) induces stem cell growth, but inhibits neuronal progenitor growth. bFGF also blocks the growth of tumors that originate from progenitors. This study suggests bFGF-like molecules might be used to treat medulloblastoma -- but only tumors with the appropriate origins.
California Institute for Regenerative Medicine, NIH/National Institute of Mental Health, Pediatric Brain Tumor Foundation

Contact: Heather Buschman, Ph.D.
hbuschman@sanfordburnham.org
858-795-5343
Sanford-Burnham Medical Research Institute

Public Release: 13-Nov-2012
PLOS ONE
Stem cell finding could advance immunotherapy for lung cancer
A University of Cincinnati Cancer Institute lung cancer research team reports that lung cancer stem cells can be isolated -- and then grown -- in a preclinical model, offering a new avenue for investigating immunotherapy treatment options that specifically target stem cells.
University of Cincinnati

Contact: Amanda Harper
amanda.harper@uc.edu
513-558-4657
University of Cincinnati Academic Health Center

Public Release: 13-Nov-2012
Journal of Clinical Oncology
Study demonstrates that earlier end of life care discussions are linked to less aggressive care in final days of life
Summary of a study being published online Nov. 13, 2012 in the Journal of Clinical Oncology, reporting that earlier discussions about end of life care preferences are strongly associated with less aggressive care in the last days of life and increased use of hospice care for patients with advanced cancer.

Contact: Amanda Narod
amanda.narod@asco.org
571-483-1364
American Society of Clinical Oncology

Public Release: 13-Nov-2012
Cancer Cell
Targeting downstream proteins in cancer-causing pathway shows promise in cell, animal model
The cancer-causing form of the gene Myc alters the metabolism of mitochondria, the cell's powerhouse, making it dependent on the amino acid glutamine for survival. Depriving cells of glutamine selectively induces programmed cell death in cells overexpressing mutant Myc. Using Myc-active neuroblastoma cells, a team three priotein executors of the glutamine-starved cell, representing a downstream target at which to aim drugs. Roughly 25 percent of all neuroblastoma cases are associated with Myc-active cells.
NIH/National Cancer Institute, Howard Hughes Medical Institute

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Public Release: 12-Nov-2012
Cancer Cell
Scientists at IRB BARCELONA discover a key process that allows colon cancer to metastasize
Researchers at the IRB Barcelona have determined that the ability of colon cancer to metastasize lies in the healthy cells, called stroma, that surround the tumor. Although the stroma has long been hypothesized to be complicit in this process, this study marks the first time that healthy cells in the microenvironment have been observed to play a fundamental role in allowing metastasis to occur in a specific tumor type.

Contact: Sònia Armengou
armengou@irbbarcelona.org
34-934-037-255
Institute for Research in Biomedicine (IRB Barcelona)

Public Release: 12-Nov-2012
International Conference on Pattern Recognition (ICPR 2012) Tsukuba, Japan
New statistical method offers automatic mitotic cell detection for cancer diagnosis
Scientists have developed a statistical image analysis method which can assist in the grading of breast cancer by automatically segmenting tumour regions and detecting dividing cells in tissue samples.

Contact: Anna Blackaby
44-024-765-75910
University of Warwick

Public Release: 12-Nov-2012
Deutsches Ärzteblatt International
Place in the sun carries risks for outdoor workers
Those individuals who work outdoors with resultant sun exposure are at increased risk for non-melanoma skin cancers, such as squamous cell carcinoma and basal cell carcinoma. Manige Fartasch shows that the connection between occupational UV exposure and squamous cell carcinoma is now well-established in her review article in issue 43 of Deutsches Arzteblatt International.

Contact: Manigé Fartasch
fartasch@ipa.ruhr-uni-bochum.de
Deutsches Aerzteblatt International

Public Release: 12-Nov-2012
Nanotechnology
UT Arlington physics team demonstrates new power generation technique
University of Texas at Arlington and Louisiana Tech University researchers created a hybrid nanomaterial that can be used to convert light and thermal energy into electrical current. The team built a prototype thermoelectric generator they hope can eventually produce milliwatts for use in devices such as self-powering sensors, low-power electronic devices and implantable biomedical micro-devices, they said. UT Arlington's Wei Chen has also coupled gold nanoparticles with copper sulfide nanoparticles for potential use in cancer therapy.

Contact: Traci Peterson
tpeterso@uta.edu
817-272-9208
University of Texas at Arlington

Public Release: 12-Nov-2012
Cancer Cell
Gene sequencing project identifies abnormal gene that launches rare childhood leukemia
Research led by the St. Jude Children's Research Hospital -- Washington University Pediatric Cancer Genome Project has identified a fusion gene responsible for almost 30 percent of a rare subtype of childhood leukemia with an extremely poor prognosis.
National Institutes of Health, Pediatric Cancer Genome Project, ALSAC, and others.

Contact: Summer Freeman
summer.freeman@stjude.org
901-595-3061
St. Jude Children's Research Hospital

Public Release: 12-Nov-2012
Nature Genetics
Duke Medicine news -- Genome sequencing of Burkitt Lymphoma reveals unique mutation
In the first broad genetic landscape mapped of a Burkitt lymphoma tumor, scientists at Duke Medicine and their collaborators identified 70 mutations, including several that had not previously been associated with cancer and a new one that was unique to the disease.
National Institutes of Health, American Cancer Society

Contact: Sarah Avery
sarah.avery@duke.edu
919-660-1306
Duke University Medical Center

Public Release: 12-Nov-2012
Cancer Discovery
PI3-kinase and PARP inhibitor combo may offer new treatment option for triple-neg breast cancers
PI3-kinase inhibitors sensitized tumors to PARP inhibitors. Combination significantly prolonged progression-free survival in mouse model.
Stand Up To Cancer

Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research

Showing releases 101-125 out of 1136.

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