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Showing releases 101-125 out of 1324.

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Public Release: 11-May-2015
Journal of Clinical Oncology
Breast cancer patients 60+ with luminal A subtype may not need radiation if on hormone therapy
Women with luminal A subtype breast cancer -- and particularly those older than 60 -- may not need radiation treatment if they are already taking hormone therapy, shows clinical research led by radiation oncologists at the Princess Margaret Cancer Centre published online today in the Journal of Clinical Oncology.

Contact: Jane Finlayson
jane.finlayson@uhn.ca
416-946-2846
University Health Network

Public Release: 11-May-2015
Oncogene
How cancer tricks the lymphatic system into spreading tumors
Cancer researchers and immunologists at Sweden's Karolinska Institutet have discovered how cancer cells can infiltrate the lymphatic system by 'disguising' themselves as immune cells (white blood cells).
Swedish Research Council, Swedish Cancer Society, Children's Cancer Foundation, Swedish Society for Medical Research, Karolinska Institutet, Nordic Cancer Union

Contact: KI Press Office
pressinfo@ki.se
46-852-486-077
Karolinska Institutet

Public Release: 11-May-2015
Cancer Cell
First cancer-promoting oncogenes discovered in rare brain tumor of children and adults
Researchers have identified three genes that play a pivotal role in the brain tumor choroid plexus carcinoma, a discovery that lays the groundwork for more effective treatment of this rare, often fatal cancer. St. Jude Children's Research Hospital scientists led the study, which appears today in the journal Cancer Cell.
National Institutes of Health, US Department of Defense, and ALSAC

Contact: Carrie Strehlau
carrie.strehlau@stjude.org
901-595-2295
St. Jude Children's Research Hospital

Public Release: 11-May-2015
Nature Biotechnology
Using CRISPR, biologists find a way to comprehensively identify anti-cancer drug targets
Imagine having a complete catalog of the best drug targets to hit in a deadly form of cancer. Imagine having a master catalog of such targets for all major cancers. Scientists at CSHL have published a method of doing precisely this, using the revolutionary gene-editing technology called CRISPR.
National Institutes of Health, Burroughs-Wellcome Fund, Alex's Lemonade Stand Foundation, National Cancer Center, Simons Center for Quantitative Biology

Contact: Peter Tarr
tarr@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory

Public Release: 11-May-2015
Cancer Discovery
First-in-class antibody mixture shows clinical activity against Tx-resistant, advanced CRC
Sym004, a mixture of two anti-epidermal growth factor receptor (EGFR) antibodies, was found to be clinically active in patients with advanced colorectal cancer that had become resistant to prior anti-EGFR therapies.
Symphogen A/S, Merck KGaA

Contact: Lauren Riley
lauren.riley@aacr.org
215-446-7155
American Association for Cancer Research

Public Release: 11-May-2015
Cancer
Certain treatments for childhood cancer may increase obesity risk later in life
Individuals who had cancer as a child may be at increased risk of being obese due to the therapies they received during their youth.

Contact: Evelyn Martinez
sciencenewsroom@wiley.com
Wiley

Public Release: 11-May-2015
Annals of Internal Medicine
ACP calls for policies to support transgender rights, same-sex marriage
ACP officially supports transgender rights and same-sex marriage, opposes conversion therapy in new policy position paper A new policy position paper from the American College of Physicians offers recommendations on how to achieve health care equality for lesbian, gay, bisexual, and transgender patients. Among its recommendations, ACP calls for comprehensive transgender health care services included in health benefits plans and civil marriage rights for same-sex couples.

Contact: Angela Collom
acollom@acponline.org
215-351-2653
American College of Physicians

Public Release: 11-May-2015
Annals of Family Medicine
May/June 2015 Annals of Family Medicine tip sheet
This tip sheet features original research and commentary published in the May/June 2015 issue of Annals of Family Medicine.

Contact: Angela Sharma
asharma@aafp.org
913-269-2269
American Academy of Family Physicians

Public Release: 11-May-2015
Nature
Disrupting cancer pathway could enhance new immunotherapies
Understanding how to overrule a signaling pathway that can cause treatments to fail in metastatic melanoma patients should help physicians extend the benefits of recently approved immunity-boosting drugs known as checkpoint inhibitors. Researchers from the University of Chicago show how these tumors shield themselves from T cells by producing high levels of beta-catenin, an intracellular messenger. They show how beta-catenin prevents T cell invasion and undermines treatment. They also suggest ways to circumvent this roadblock.
Melanoma Research Alliance, Cancer Research Institute

Contact: Kevin Jiang
kevin.jiang@uchospitals.edu
773-795-5227
University of Chicago Medical Center

Public Release: 11-May-2015
Oncotarget
Advanced viral gene therapy eradicates prostate cancer in preclinical experiments
Even with the best available treatments, the median survival of patients with metastatic, hormone-refractory prostate cancer is only two to three years. Driven by the need for more effective therapies for these patients, researchers at VCU Massey Cancer Center and the VCU Institute of Molecular Medicine have developed a unique approach that uses microscopic gas bubbles to deliver directly to the cancer a viral gene therapy in combination with an experimental drug that targets a specific gene driving the cancer's growth.
NIH/National Cancer Institute, US Department of Defense, National Foundation for Cancer Research, VCU Massey Cancer Center

Contact: John Wallace
wallacej@vcu.edu
804-628-1550
Virginia Commonwealth University

Public Release: 11-May-2015
Journal of Cell Biology
Leicester research team identifies potential new targets for cancer treatments
Research papers identify key steps in cell division -- and potential to inhibit cancer cell division.
Worldwide Cancer Research, Cancer Research UK, Wellcome Trust, Biotechnology and Biological Sciences Research Council, Medical Research Council, Hope Against Cancer

Contact: Andrew Fry
amf5@le.ac.uk
01-162-297-069
University of Leicester

Public Release: 11-May-2015
Journal of the American Board of Family Medicine
Patients more likely to get HPV vaccine after electronic health record prompts
The HPV vaccine has the lowest completion rates of any other vaccine. New study shows that reminders via electronic health records may help improve rates.
NIH/National Cancer Institute

Contact: Beata Mostafavi
bmostafa@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 11-May-2015
Nature Communications
Dying cells can protect their stem cells from destruction
Cells dying as the result of radiation exposure or chemotherapy can send a warning to nearby stem cells or to tumor-initiating cells. The chemical signal allows both the tissue-repair cells and the tumor-forming cells to escape the same fate. This may explain why many cancers return after initially responding to treatment and could lead to new, more effective cancer drugs. These might block the warning signal that stops the cells from going into programmed cell death.
American Heart Association, Western State Affiliate Postdoctoral Fellowship, National Institutes of Health

Contact: Leila Gray
leilag@uw.edu
206-685-0381
University of Washington Health Sciences/UW Medicine

Public Release: 11-May-2015
Cancer
Childhood cancer treatment and age influence obesity risk for childhood cancer survivors
Childhood cancer survivors -- especially those whose treatment included brain irradiation or chemotherapy with glucocorticoids -- are 14 percent more likely to be obese than their healthy peers. The St. Jude Children's Research Hospital study appears today in the journal Cancer.
NIH/National Cancer Institute, ALSAC

Contact: Carrie Strehlau
carrie.strehlau@stjude.org
901-595-2295
St. Jude Children's Research Hospital

Public Release: 11-May-2015
Journal of Nutritional Biochemistry
New Harvard research finds walnuts may help slow colon cancer growth
New Harvard research finds walnuts may help slow colon cancer growth. A walnut-enriched diet may cause beneficial genetic changes in animal cancer cells, affecting inflammation, blood supply and growth of tumors.
California Walnut Commission, American Institute for Cancer Research

Contact: Erin Farkaly
erin.farakly@edelman.com
415-486-3256
Edelman Seattle

Public Release: 11-May-2015
Nature Communications
Gene found that is essential to maintaining breast and cancer stem cells
The gene and hormone soup that enables women to breastfeed their newborns also can be a recipe for breast cancer, particularly when the first pregnancy is after age 30.

Contact: Toni Baker
tbaker@gru.edu
706-721-4421
Medical College of Georgia at Georgia Regents University

Public Release: 11-May-2015
American Journal of Epidemiology
Study links father's age and risk of blood cancer as an adult
A new study links a father's age at birth to the risk that his child will develop blood and immune system cancers as an adult, particularly for only children.
American Cancer Society

Contact: David Sampson
david.sampson@cancer.org
American Cancer Society

Public Release: 11-May-2015
Journal of Clinical Oncology
Men with high estrogen levels could be at greater risk of breast cancer
Men with naturally high levels of the female hormone estrogen may have a greater risk of developing breast cancer.
Cancer Research UK, NIH/National Cancer Institute, Deutsche Krebshilfe, Deutsches Krebforschungszentrum, German Federal Ministry of Education and Research, Swedish Cancer Society, Swedish Scientific Council, Regional Government of Skå

Contact: Emily Head
emily.head@cancer.org.uk
44-203-469-6189
Cancer Research UK

Public Release: 11-May-2015
Cancer Cell
Study may suggest new strategies for myelodysplastic syndromes treatment
A study revealing fresh insight about chromosome 'tails' called telomeres may provide scientists with a new way to look at developing treatments or even preventing a group of blood cell disorders known as myelodysplastic syndromes.

Contact: Ron Gilmore
rlgilmore1@mdanderson.org
713-745-1898
University of Texas M. D. Anderson Cancer Center

Public Release: 11-May-2015
Physical Review Letters
A turning point in the physics of blood
In a paper published May 1, 2015, in the journal Physical Review Letters, Professor Mike Graham and Ph.D. students Kushal Sinha and Rafael G. Henríquez Rivera lay out an equation that yields simple predictions as to how quickly blood cells will migrate away from blood-vessel walls, how they will behave when they collide with each other and accordingly how they will segregate during flow.

Contact: Mike Graham
mdgraham@wisc.edu
608-265-3780
University of Wisconsin-Madison

Public Release: 8-May-2015
ecancermedicalscience
Will Mexico's aging population see cancer care as a priority?
Mexico is the second largest economy in Latin America -- and its population is aging rapidly. Researchers offer new predictions and suggestions for lessening the impact of Mexico's cancer burden.

Contact: Audrey Nailor
audrey@ecancer.org
44-011-790-94742
ecancermedicalscience

Public Release: 8-May-2015
PLOS Computational Biology
UM biologist advances cancer research with new data analysis techniques
Patience and persistence are beginning to pay off for University of Montana Professor Mark Grimes, whose research about the behavior of cell proteins in childhood cancer recently was published by the PLOS Computational Biology.

Contact: Mark Grimes
mark.grimes@mso.umt.edu
406-243-4977
The University of Montana

Public Release: 8-May-2015
Toxicological Sciences
New method developed to assess cancer risk of pollutants
Scientists have developed a faster, more accurate method to assess cancer risk from certain common environmental pollutants.
NIH/National Institute of Environmental Health Sciences

Contact: Susan Tilton
susan.tilton@oregonstate.edu
541-737-1386
Oregon State University

Public Release: 8-May-2015
Oncotarget
New combination treatment strategy to 'checkmate' glioblastoma
Therapies that specifically target mutations in a person's cancer have been much-heralded in recent years, yet cancer cells often find a way around them. To address this, researchers at University of California, San Diego School of Medicine and Moores Cancer Center identified a promising combinatorial approach to treating glioblastomas, the most common form of primary brain cancer. The study published May 5 by Oncotarget.
Sontag Foundation, Burroughs Wellcome Foundation, Kimmel Foundation, Doris Duke Foundation and Forbeck Foundation

Contact: Heather Buschman
hbuschman@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 8-May-2015
Journal of Molecular Biology
Tracking defects caused by brain tumor mutation yields insight to advance targeted therapy
St. Jude Children's Research Hospital scientists have gained ground toward developing more targeted therapies for the most common childhood brain tumor. The findings appear today in the Journal of Molecular Biology. The findings involve the DDX3X gene. In 2012, the St. Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project highlighted DDX3X as a promising focus for efforts to develop targeted therapies against medulloblastoma. Such treatments target the genetic mistakes that give rise to the brain tumor's four subtypes.
National Institutes of Health, ALSAC

Contact: Carrie Strehlau
carrie.strehlau@stjude.org
901-595-2295
St. Jude Children's Research Hospital

Showing releases 101-125 out of 1324.

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