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Showing releases 101-125 out of 1337.

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Public Release: 29-Sep-2015
MRI technique could reduce need for breast biopsies
A magnetic resonance breast imaging technique that uses no ionizing radiation or contrast agent could reduce unnecessary biopsies by providing additional information about suspicious findings on X-ray screening mammography, according to a new study.

Contact: Linda Brooks
Radiological Society of North America

Public Release: 29-Sep-2015
Population Health Management
Underdetection, not overdiagnosis, is the real problem in breast cancer screening
While screening mammography has a well-established history of reducing death from breast cancer and enabling earlier detection of breast disease, questions regarding overtreatment and overdiagnosis have entered the screening debate. A new review article discusses the topics of overdiagnosis and overtreatment and the role of providers and technology to address the issues in the context of population health. The article appears in a new supplement to Population Health Management.

Contact: Kathryn Ryan
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 29-Sep-2015
Journal of Clinical Pathology
Intratumor morphological heterogeneity of cancer is not related to chromosome aberrations
Intratumor morphological heterogeneity (diversity) of breast cancer is not related to chromosome aberrations. This conclusion was made based on the study of one case with aggressive variant of breast cancer -- invasive micropapillary carcinoma by researchers from Tomsk State University, Tomsk Cancer Research Institute, and Institute of Medical Genetics.

Contact: Tatiana Arsenyeva
National Research Tomsk State University

Public Release: 29-Sep-2015
Scientists pioneer 3-D-printed drug delivering micro-needles
Researchers have developed a new technique to produce a 3-D 'micro-printed' array of needles capable of drug delivery. The technique would offer a pain-free drug delivery device that would allow drugs to diffuse within the body as the biomaterial device degrades in the body. This offers treatments for a wide range of diseases, including melanoma cancers. The results are published Sept. 30 in the journal Biofabrication.

Contact: Steve Pritchard
Institute of Physics

Public Release: 29-Sep-2015
Advanced Materials
Researchers disguise drugs as platelets to target cancer
Researchers have for the first time developed a technique that coats anticancer drugs in membranes made from a patient's own platelets, allowing the drugs to last longer in the body and attack both primary cancer tumors and the circulating tumor cells that can cause a cancer to metastasize. The work was tested successfully in an animal model.
National Institutes of Health

Contact: Matt Shipman
North Carolina State University

Public Release: 29-Sep-2015
International Journal of Medical Engineering and Informatics
Risk factors for prostate cancer
New research suggests that age, race and family history are the biggest risk factors for a man to develop prostate cancer, although high blood pressure, high cholesterol, vitamin D deficiency, inflammation of prostate, and vasectomy also add to the risk. In contrast, obesity, alcohol abuse, and smoking show a negative association with the disease. Details are reported in the International Journal of Medical Engineering and Informatics.

Contact: Albert Ang
Inderscience Publishers

Public Release: 28-Sep-2015
European Cancer Congress (ECC2015)
New England Journal of Medicine
Cancer diagnosis while pregnant should not lead to treatment delay or end of pregnancy
Women who are pregnant when diagnosed with cancer can start treatment for their disease immediately and do not need to terminate their pregnancy due to worries over the effects of therapy on the development of their child.
Belgian National Cancer plan, Research Fund Flanders, Stichting tegen Kanker, KU Leuven, UZ Leuven

Contact: Emma Mason
ECCO-the European CanCer Organisation

Public Release: 28-Sep-2015
Attacking acute myeloid leukemia
A team of Harvard researchers and other collaborators led by Professor of Chemistry and Chemical Biology Matthew Shair has demonstrated that a molecule isolated from sea sponges and later synthesized in Shair's lab, can halt the growth of acute myeloid leukemia cells and could open the door to a new treatment for leukemia. The study is described in a September 28th paper in Nature.

Contact: Peter Reuell
Harvard University

Public Release: 28-Sep-2015
European Cancer Congress (ECC2015)
Social deprivation and gender affects incidence of Hodgkin's lymphoma
Living in overcrowded conditions appears to protect children and young adults against developing a particular type of Hodgkin's lymphoma, a cancer that originates from the lymphocytes (white blood cells).
North of England Children's Cancer Research Fund

Contact: Mary Rice
ECCO-the European CanCer Organisation

Public Release: 28-Sep-2015
JAMA Internal Medicine
UC Davis researcher advocates ending Medicare coverage of controversial mammography tool
A costly tool used on nearly all mammograms does not increase cancer detection rates and should no longer be covered by Medicare, argues Joshua Fenton, a family physician and comparative effectiveness researcher in an editorial published online today in the Journal of the American Medical Association Internal Medicine.

Contact: Dorsey Griffith
University of California - Davis Health System

Public Release: 28-Sep-2015
JAMA Internal Medicine
Computer-aided detection does not improve breast cancer screening
In the largest study to date of computer-aided detection (CAD) for mammography, the Breast Cancer Surveillance Consortium found CAD improved no measure of accuracy of screening mammography: how often cancers were detected, how often something was incorrectly labeled as cancer, how often they were missed -- and may even have missed more cancers.
NIH/National Cancer Institute

Contact: Katie Marquedant
Group Health Research Institute

Public Release: 28-Sep-2015
Coverage of celebrity's mastectomy has improved awareness of reconstructive breast surgery options
A new study found improved public awareness about reconstructive breast surgery options following Angelina Jolie's decision to undergo a double mastectomy and subsequent reconstruction.

Contact: Evelyn Martinez

Public Release: 28-Sep-2015
Endocrine Reviews
Chemical exposure linked to rising diabetes, obesity risk
Emerging evidence ties endocrine-disrupting chemical exposure to two of the biggest public health threats facing society -- diabetes and obesity, according to the executive summary of an upcoming Scientific Statement issued today by the Endocrine Society.

Contact: Jenni Glenn Gingery
The Endocrine Society

Public Release: 28-Sep-2015
ERS International Congress 2015
Lancet Respiratory Medicine
First UK Biobank genetic study reveals new links between lung disease and smoking behavior
Smokers who survive their habit into old age may hold the key to better lung health for all, according to a Medical Research Council-funded study involving researchers at the University of Nottingham and the University of Leicester.
Medical Research Council

Contact: Emma Rayner
University of Nottingham

Public Release: 28-Sep-2015
European Cancer Congress (ECC2015)
First 'targeted' treatment for small cell lung cancer shows promise
Today US researchers will present two novel findings with important implications for treatment of small cell lung cancer at the 2015 European Cancer Congress.

Contact: Mary Rice
ECCO-the European CanCer Organisation

Public Release: 28-Sep-2015
New England Journal of Medicine
Multi-gene test enables some breast cancer patients to safely avoid chemotherapy
A major study published in the New England Journal of Medicine is providing the best evidence to date that a 21-gene test done on the tumor can identify breast cancer patients who can safely avoid chemotherapy.
NIH/National Cancer Institute

Contact: Jim Ritter
Loyola University Health System

Public Release: 28-Sep-2015
New England Journal of Medicine
Immunotherapy superior to chemotherapy for lung cancer in trial involving UTSW
An international team of cancer researchers that included UT Southwestern Medical Center physicians announced 'game-changing results' using the immunotherapy drug nivolumab to treat certain lung cancers that failed to respond to first-line therapies.
Bristol-Myers Squibb

Contact: Lori Sundeen Soderbergh
UT Southwestern Medical Center

Public Release: 28-Sep-2015
European Cancer Congress 2015
New England Journal of Medicine
New drug improves outcome in treatment resistant kidney cancer
A new drug for renal cell carcinoma slowed the growth of advanced kidney cancer in patients who became resistant to the first-line therapies that had previously kept it in check, according to results from a clinical trial led by Dana-Farber Cancer Institute.
Exelixis, Inc.

Contact: Teresa M Herbert
Dana-Farber Cancer Institute

Public Release: 28-Sep-2015
Proceedings of the National Academy of Sciences
Scientists decode structure at root of muscular disease
Researchers at Rice University and Baylor College of Medicine have unlocked the structural details of a protein seen as key to treating nemaline myopathy, a neuromuscular disease that causes muscle weakness.
National Institutes of Health, Welch Foundation

Contact: David Ruth
Rice University

Public Release: 28-Sep-2015
European Cancer Congress (ECC2015)
Kolltan Pharmaceuticals announces KTN0158 preclinical data at ESMO 2015
Substantial shrinkage in tumors and favorable results from nonclinical toxicology studies support IND filing in 2015. Initiation of Phase 1 clinical trial in GIST and other KIT-dependent solid tumors anticipated in 2016.
Kolltan Pharmaceuticals

Contact: Justin Jackson
Kolltan Pharmaceuticals, Inc.

Public Release: 28-Sep-2015
Early exposure to tobacco as a cause of behavioral problems in children
Researchers from Inserm and Pierre and Marie Curie University, in collaboration with the university hospitals of six French cities, have analyzed data on pre- and postnatal exposure to tobacco in the homes of 5,200 primary school children.

Contact: Isabella Annesi-Maesano
INSERM (Institut national de la santé et de la recherche médicale)

Public Release: 28-Sep-2015
Scientific Reports
Scientists use microchip approach to visualize human breast cancer proteins
Virginia Tech Carilion Research Institute scientists present a new molecular toolkit to investigate protein assemblies natively formed in the context of human disease. BRCA1 gene regulatory complexes from cancer cells were visualized for the first time.

Contact: Paula Brewer Byron
Virginia Tech

Public Release: 28-Sep-2015
European Cancer Congress (ECC2015)
New England Journal of Medicine
New England Journal of Medicine publishes initial data from TAILORx breast cancer trial
Initial results announced today from the Trial Assigning IndividuaLized Options for Treatment (Rx), or TAILORx, a prospectively conducted global trial in 10,000+ women with early stage breast cancer, found that 1,626 trial participants with low Oncotype DX® Recurrence Score® results (≤ 10) who got hormonal therapy alone without chemotherapy had <1 percent chance of distant recurrence at five years, providing evidence that women in the future may effectively forego chemotherapy if their Recurrence Score is ≤10.
NIH/National Cancer Institute

Contact: ECOG-ACRIN Office of Communications
ECOG-ACRIN Cancer Research Group

Public Release: 28-Sep-2015
Journal of Clinical Oncology
HRT safe and perhaps beneficial in women treated for ovarian cancer, major trial shows
Women with the commonest type of ovarian cancer can safely take hormone replacement therapy (HRT), and it could have a beneficial effect on their survival, a long-term clinical trial reports. The 24-year, phase III international trial provides the strongest evidence yet that women with epithelial ovarian cancer -- which accounts for 80-90 per cent of cases -- can safely take HRT during or after their treatment.
The Institute of Cancer Research London, Cancer Research UK

Contact: Henry French
Institute of Cancer Research

Public Release: 27-Sep-2015
2015 Annual Meeting & OTO EXPO
Cancer, sinusitis, tinnitus, and exposure to tobacco smoke
Research to be presented tomorrow at the 2015 Annual Meeting & OTO EXPOSM of the American Academy of Otolaryngology--Head and Neck Surgery Foundation (AAO-HNSF) spans across the otolaryngology specialty.

Contact: Lindsey Walter
American Academy of Otolaryngology - Head and Neck Surgery

Showing releases 101-125 out of 1337.

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