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Showing releases 1001-1025 out of 1212. << < 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 > >>
Public Release: 7-Mar-2013
American Academy of Microbiology releases resistance report What do cancer cells, weeds, and pathogens have in common? They all evolve resistance to the treatments that are supposed to eliminate them. However, researchers developing the next generation of antibiotics, herbicides, and anti-cancer therapeutics rarely come together to explore the common evolutionary principles at work across their different biological systems. Contact: Garth Hogan
Public Release: 7-Mar-2013
 Genetics in MedicineGenomic screening for improved public health In 10 years' time, routine preventive health care for adults may include genetic testing. As genomic testing prepares to enter the realm of general medical care, an interdisciplinary team of researchers is suggesting in the May 2013 issue of Genetics in Medicine, the peer-reviewed journal of the American College of Medical Genetics and Genomics, that now is the time to explore genetic testing to identify people at high risk for carefully selected, preventable disease. Contact: Kathy Beal
Public Release: 7-Mar-2013
Genes & DevelopmentVHIO scientists eradicate lung tumors in a pre-clinical mouse model The results, to be published in the journal Genes & Development, confirm that repeated, long-term treatment does not cause side effects. Importantly, no resistance to treatment has been encountered, which is one of the biggest concerns with anticancer therapies. These results show that anticancer therapies based on Myc inhibition are a safe, effective therapeutic option in new drug development. Contact: Amanda Wren
Public Release: 7-Mar-2013
Cell ReportsDual systems key to keeping chromosomes intact USC scientists have discovered how two different structural apparatuses collaborate to protect repetitive DNA when it is at its most vulnerable -- while it is being unzipped for replication. 
National Institutes of Health, National Science Foundation
Contact: Robert Perkins
Public Release: 7-Mar-2013
Genome ResearchResearchers find molecular switch turning on self-renewal of liver damage The liver is one of the few organs in our body that can regenerate itself, but how it occurs is a biological mystery. New research from BRIC, University of Copenhagen has identified a protein complex that act to switch on a self-regeneration program in the liver. "Our new data challenge the predominant 'stem cell-mania' as the results reveal important molecular mechanisms that enable ordinary liver cells to repair tissue damage," says Head of Clinic and professor, Bo Porse.
Danish Cancer Society, Novo Nordisk Foundation
Contact: Bo Porse
Public Release: 7-Mar-2013
Molecular CellA cancer-promoting protein is found to also suppress cell growth The cancer-causing oncogene SRSF1, first discovered through its role in splicing, is now shown also to activate cell-growth arrest, or senescence. In states of ribosomal stress or overexpression of SRSF1 it binds to the ribosomal protein RPL5 and prevents degradation of p53. This leads to the phenomenon of oncogene-induced senescence, a program that prevents transformation of normal cells into proliferating cancer cells.
NIH/National Cancer Institute
Contact: Edward Brydon Ph.D.
Public Release: 7-Mar-2013
American College of Cardiology's 62nd Annual Scientific Session & ExpoAfrican-American breast cancer survivors face higher risk of heart failure African-American women who survive breast cancer are more likely to develop heart failure than other women who have beaten the disease, according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session. Contact: Beth Casteel
Public Release: 6-Mar-2013
Cancer Prevention ResearchVisceral fat causally linked to intestinal cancer The loss of fat by surgical removal or a calorie-restricted diet reduced the likelihood of developing intestinal tumors. Differences were found between male and female mice. This study emphasizes the need for strategies to reduce visceral fat. Contact: Jeremy Moore
Public Release: 6-Mar-2013
Cancer Prevention ResearchBiomarkers may help predict progression of Barrett's esophagus to esophageal adenocarcinoma Expression of most microRNAs was similar between the two conditions. A small number were differentially expressed. These microRNAs could be biomarkers for early diagnosis of progression. Contact: Jeremy Moore
Public Release: 6-Mar-2013
NatureOrigin of aggressive ovarian cancer discovered Cornell University researchers have discovered a likely origin of epithelial ovarian cancer (ovarian carcinoma), the fifth leading cause of cancer death among women in the United States.
NIH/National Cancer Institute, National Institutes of Health, New York State Stem Cell Science
Contact: Joe Schwartz
Public Release: 6-Mar-2013
New England Journal of MedicineInvolving other providers in palliative care may help meet growing demand As baby-boomers age and the number of people with serious chronic illnesses rises, demand for experts in palliative medicine is sure to outstrip supply. In a perspective published in today's New England Journal of Medicine, Timothy E. Quill, M.D., president of the American Academy of Hospice and Palliative Medicine, suggests that arming generalists and other specialists with primary palliative care skills is a practical, cost-effective and sustainable way to expand the delivery of palliative care. Contact: Lori Barrette
Public Release: 6-Mar-2013
Nucleic Acids ResearchScientists at A*STAR's Genome Institute of Singapore catch evolving germs and cancer cells early Scientists at A*STAR's Genome Institute of Singapore have developed a novel technique to precisely monitor and study the evolution of micro-organisms such as viruses and bacteria. This is an extremely important capability as it allows scientists to investigate if new drugs designed to kill them are working, and to catch the development of resistance early on.
A*STAR
Contact: Winnie Lim
Public Release: 6-Mar-2013
Journal of the American Chemical SocietyKilling cancer cells with acid reflux A University of Central Florida chemist has come up with a unique way to kill certain cancer cells -- give them acid reflux.
National Institutes of Health, National Science Foundation
Contact: Zenaida Gonzalez Kotala
Public Release: 6-Mar-2013
Nature CommunicationsProtein lost in tumors blocks normal cells from being reprogrammed into stem cells Researchers from the Icahn School of Medicine at Mount Sinai have discovered that a particular protein prevents normal cells from being reprogrammed into cells that resemble stem cells, providing new insight into how they may lose their plasticity during normal development. Contact: Press Office
Public Release: 6-Mar-2013
BMC MedicineA sausage a day is too many Anyone who eats over 40 grams a day of sausage products or other kinds of processed meat is asking for trouble: The risk of mortality increases by 18 percent for every 50 grams of processed meat per day. This is the result of a study conducted with around 450,000 participants by the Institute of Social and Preventive Medicine at the University of Zurich in collaboration with research colleagues from all over Europe. Contact: Sabine Rohrmann
Public Release: 5-Mar-2013
Science SignalingHope in stopping melanoma from spreading: Inhibiting protein prevents metastasis to lungs in mice Researchers have identified a critical protein role in the metastasis of melanoma, the most serious form of skin cancer. Inhibition of the protein known as adenosine diphosphate ribosylation factor 6 (ARF6) reduces the spread of melanoma to the lungs in mice, according to a study published in the March 5 issue of Science Signaling online, suggesting that targeting ARF6 may be an effective approach to preventing melanoma metastasis.
Huntsman Cancer Foundation
Contact: Phil Sahm
Public Release: 5-Mar-2013
CellUT Southwestern scientists make mouse model of human cancer, demonstrate cure Scientists report the first successful blocking of tumor development in a genetic mouse model of an incurable human cancer.
NIH/National Cancer Institute, National Institutes of Health, Department of Defense, Burroughs Wellcome Fund, American Cancer Society
Contact: Deborah Wormser
Public Release: 5-Mar-2013
Annals of Internal MedicineColonoscopy screening reduces risk of advanced colorectal cancer A new study led by a researcher at the Penn Medicine adds support to current medical recommendations stating that screening colonoscopy substantially reduces an average-risk adult's likelihood of being diagnosed with advanced colorectal cancer (CRC) in either the right or left side of the colon. In the new study, researchers noted an overall 70 percent reduction of advanced CRC diagnoses associated with receiving a screening colonoscopy. The full results of the study appear online in the Annals of Internal Medicine.
NIH/National Cancer Institute
Contact: Katie Delach
Public Release: 5-Mar-2013
Nature NeuroscienceResearch leads to better understanding of peripheral neuropathy Researchers from Plymouth University Peninsula Schools of Medicine and Dentistry are part of an international team that has for the first time unlocked the key to a mechanism for peripheral neuropathy in people with multiple brain tumors. Contact: Andrew Gould
Public Release: 5-Mar-2013
Journal of Nuclear MedicineNovel small molecules used to visualize prostate cancer Two novel radiolabeled small molecules targeting prostate-specific membrane antigen have excellent potential for further development as diagnostic and therapeutic radiopharmaceuticals, according to research published this month in The Journal of Nuclear Medicine. The imaging agents -- 123I-MIP-1072 and 123I-MIP-1095 -- were shown to have a high sensitivity of lesion detection in bone, soft tissue and the prostate gland with minimal retention in non-target tissue. Contact: Susan Martonik
Public Release: 5-Mar-2013
Journal of Clinical Endocrinology and MetabolismBetter estrogen-testing methods needed to improve patient care In a position statement unveiled today, the Endocrine Society advocates that all methods for measuring estrogens, which play a crucial role in human biology, be made traceable to a common standard. Contact: Jenni Glenn Gingery
Public Release: 5-Mar-2013
RadiologyFocal therapy offers middle ground for some prostate cancer patients For men with low-risk prostate cancer, focal laser ablation treats just the diseased portion of the prostate rather than the entire gland. A phase 1 trial found it was safe. None of the nine men in the study had a significant side effect. Seven of the nine patients had no evidence of disease six months later.
Partnership for Cures Foundation, Visualase
Contact: John Easton
Public Release: 5-Mar-2013
Molecular MicrobiologyNew insight into double-protected dance of cell division "We know that a process that has to happen as reliably and stably as cell division also has to be flexible enough to allow the organism to grow and respond to its ever-changing environment. We're interested in uncovering all the steps and back-up safeguards that cells use to robustly protect replication while at the same time allowing other functions to proceed."
National Institutes of Health, University of Massachusetts Amherst
Contact: Janet Lathrop
Public Release: 5-Mar-2013
Women's health must be priority for state health exchange marketplaces, new report says Women's issues play a major role in the health of the nation and should be a key consideration for policymakers as they design and set up the new insurance exchanges, according to a report co-authored by policy experts at the George Washington University School of Public Health and Health Services. The report offers a checklist for the state-based health insurance exchanges that helps ensure women, children and family members get the services they need. Contact: Kathy Fackelmann
Public Release: 5-Mar-2013
Qualitative Health ResearchAffordable care alone may not be enough to help Latinos overcome cancer care barriers A combination of financial, cultural and communication barriers contribute to preventing underserved Latino men with prostate cancer access to the care and treatment they need, according to a new study conducted by the UCLA School of Nursing. "Barriers to Prostate Cancer Care: Affordable Care is Not Enough," is published in the March issue of Qualitative Health Research. Contact: Laura Perry
Showing releases 1001-1025 out of 1212. << < 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 > >>
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