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Showing releases 1001-1025 out of 1386.

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Public Release: 26-Feb-2016
Immunity
Immune cell 'switch' discovery raises hopes in cancer fight
Walter and Eliza Hall Institute researchers have discovered the mechanism that drives specialised immune cells that detect and kill cancer cells in the body, offering scientists a new way to develop potential drug targets and cancer treatments.
Australian National Health and Medical Research Council, The Menzies Foundation, Victorian Government Operational Infrastructure Support Scheme

Contact: Arunee Wilson
wilson.a@wehi.edu.au
047-871-4757
Walter and Eliza Hall Institute

Public Release: 25-Feb-2016
Cell
Molecular 'brake' prevents excessive inflammation
Inflammation is a Catch-22: the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and sometimes leading to organ failure and death. Researchers at University of California, San Diego School of Medicine have discovered that a protein known as p62 acts as a molecular brake to keep inflammation in check and avoid collateral damage.
National Institutes of Health, Leukemia and Lymphoma Society, Alliance for Lupus Research, Cancer Research Institute-Irvington, German Research Foundation, Canadian Institutes of Health Research

Contact: Heather Buschman
hbuschman@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 25-Feb-2016
Neuron
Cooling technique protects speech during brain surgery
A new cooling technique can both protect the brain's speech centers during surgery and pinpoint the areas separately responsible for word formation and speech timing.

Contact: David March
david.march@nyumc.org
212-404-3528
NYU Langone Medical Center / New York University School of Medicine

Public Release: 25-Feb-2016
UEG Journal
One in 4 cases of CRC diagnosed within 2 years of a negative screening result
One in four cases of colorectal cancer (CRC) detected in a guiac faecal occult blood testing (gFOBT) programme are diagnosed within two years of a negative screening result, a study in the UEG Journal1 has found, suggesting that gFOBT should be replaced by more sensitive screening methods to improve detection rates.

Contact: Luke Paskins
media@ueg.eu
44-014-448-11099
SAGE

Public Release: 25-Feb-2016
Cell
Discovery of likely subtypes of rare childhood brain tumor signals diagnostic advance
Research led by St. Jude Children's Research Hospital and the German Cancer Research Center shows molecular analysis is likely to improve classification and diagnosis of a rare brain tumor and advance precision medicine.
National Institutes of Health, American Lebanese Syrian Associated Charities

Contact: Frannie Marmorstein
media@stjude.org
St. Jude Children's Research Hospital

Public Release: 25-Feb-2016
Cell Reports
Pancreatic cancer: Major breakthrough in our understanding of the mechanisms of the disease
A recent breakthrough has shown that pancreatic tumors often lose the ability to express a small ribonucleic acid molecule called miR-137.The loss of miR-137 works in conjunction with various mutations frequently observed in pancreatic tumors to trigger uncontrolled cell growth and then cancer.
Canadian Institutes of Health Research, Fonds de recherche du Québec - Santé

Contact: Julie Gazaille
j.cordeau-gazaille@umontreal.ca
University of Montreal

Public Release: 25-Feb-2016
JCI Insight
Understanding the role of human polyomaviruses in cancer
In this month's issue of JCI Insight, Yuan Chang and colleagues at the University of Pittsburgh Medical Center developed a new method to screen tumor samples for the presence of any human polyomavirus.
National Institutes of Health, NIH/National Cancer Institute, American Cancer Society

Contact: Corinne Williams
press_releases@the-jci.org
JCI Journals

Public Release: 25-Feb-2016
JCI Insight
Innate immune landscape in glioblastoma patient tumors
In this month's issue of JCI Insight, Amy Heimberger and colleagues at the University of Texas MD Anderson Cancer Center provide a comprehensive analysis of myeloid lineage immune cells in the circulation and in tumors of glioblastoma patients.
National Institutes of Health, Dr. Marnie Rose Foundation, University of Texas MD Anderson GBM Moonshot Program, Ethan Dmitrovsky Provost Funds

Contact: Corinne Willams
press_releases@the-jci.org
JCI Journals

Public Release: 25-Feb-2016
Medical Care
Half of elderly colorectal cancer patients receiving value-less treatment
University of Colorado Cancer Center study shows that increased treatments, cost and side effects do little to increase survival in elderly advanced stage colorectal cancer patients.

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Anschutz Medical Campus

Public Release: 24-Feb-2016
Neuro-Oncology
Malignant brain tumors most common cause of cancer deaths in adolescents and young adults
A new report published in the journal Neuro-Oncology and funded by the American Brain Tumor Association (ABTA) finds that malignant brain tumors are the most common cause of cancer-related deaths in adolescents and young adults aged 15-39 and the most common cancer occurring among 15-19 year olds.
American Brain Tumor Association

Contact: Phung Tran
ptran@abta.org
773-577-8792
American Brain Tumor Association

Public Release: 24-Feb-2016
PLOS ONE
Laser surgery opens blood-brain barrier to chemotherapy
Using a laser probe, neurosurgeons have opened the brain's protective cover, enabling them to deliver chemotherapy drugs to patients with a form of deadly brain cancer. The findings also suggest that other exciting approaches such as cancer immunotherapy also may be useful for patients with glioblastomas.
NIH/National Cancer Institute, The Foundation for Barnes-Jewish Hospital, Washington University School of Medicine in St. Louis

Contact: Judy Martin Finch
martinju@wustl.edu
314-286-0105
Washington University School of Medicine

Public Release: 24-Feb-2016
PLOS ONE
Laser treatment may boost effectiveness of brain tumor drugs
The human brain has a remarkable defense system that filters bacteria and chemicals. For brain tumor patients, the barrier works almost too well by blocking most chemotherapy drugs.
National Institutes of Health, The Barnes-Jewish Hospital Foundation, Alvin J. Siteman Cancer Center in St. Louis

Contact: Doug Bennett
dougbennett@ufl.edu
352-273-5706
University of Florida

Public Release: 24-Feb-2016
Science Translational Medicine
Study shows financial engineering could make life-saving drugs more available, affordable
Stratospheric costs for therapies not yet covered by insurance put some drugs out of reach for many patients. This study shows how securitized consumer health-care loans could spread the cost of therapies over many years, giving more patients access to drugs while generating returns to investors.

Contact: Teresa Herbert
teresa_herbert@dfci.harvard.edu
617-632-4090
Dana-Farber Cancer Institute

Public Release: 24-Feb-2016
Science Translational Medicine
Unconventional treatment strategy controls -- rather than eradicates -- cancer
Can we learn to live with--rather than kill--cancer? A new study suggests that frequent, low-dose chemotherapy that keeps tumor growth under control may be more effective than standard high-dose chemotherapy that seeks to eradicate cancer cells completely.

Contact: Science Press Package
scipak@aaas.org
202-326-6440
American Association for the Advancement of Science

Public Release: 24-Feb-2016
Cancer Prevention Research
Omega-3 fatty acids may lower breast cancer risk in postmenopausal obese women
Omega-3 fatty acids may lower the risk of breast cancer in postmenopausal obese women, according to researchers.
Susan G. Komen for the Cure

Contact: Matt Solovey
msolovey@hmc.psu.edu
717-531-8606
Penn State

Public Release: 24-Feb-2016
PLOS Pathogens
Stress wakes up sleeping herpesviruses -- but how?
Hiding their DNA genome inside the nucleus of the infected cells, the herpesviruses establish a lifelong infection in humans, and they are known to reactivate in response to different kinds of stress. The researchers have now found an important link between cellular stress responses, cell cycle regulation and virus reactivation.

Contact: Päivi Ojala
paivi.ojala@helsinki.fi
358-294-159-445
University of Helsinki

Public Release: 24-Feb-2016
Science Translational Medicine
Moffitt develops novel cancer treatment to inhibit chemo-resistance
Many patients develop resistance to standard therapies and eventually relapse. Moffitt Cancer Center researchers hope to improve treatment outcomes with development of a novel therapeutic strategy, called adaptive therapy, which is based on evolutionary principals and aims to keep resistant cells in check by maintaining a population of chemo-sensitive cells.

Contact: Steve Blanchard
steve.blanchard@moffitt.org
813-745-1718
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 24-Feb-2016
Developmental Cell
UTSW researchers build powerful 3-D microscope, create images of cancer cells
UT Southwestern Medical Center researchers have designed and built a microscope capable of creating high-resolution, 3-D images of living cancer cells in realistic, controllable microenvironments.
Cancer Prevention and Research Institute of Texas, National Institutes of Health

Contact: Deborah Wormser
deborah.wormser@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center

Public Release: 24-Feb-2016
Nature Communications
UNC-Chapel Hill researchers make groundbreaking discovery, use skin cells to kill cancer
In a first for medical science, University of North Carolina at Chapel Hill pharmacy researchers turn skin cells into cancer-hunting stem cells that destroy brain tumors known as glioblastoma -- a discovery that can offer, for the first time in more than 30 years, a new and more effective treatment for the disease.
University Cancer Research Fund, North Carolina Translational and Clinical Sciences Institute

Contact: Thania Benios
thania_benios@unc.edu
919-962-8596
University of North Carolina at Chapel Hill

Public Release: 24-Feb-2016
Nature
Pancreatic cancer is 4 diseases, each with new treatment possibilities
An international team led by Australian researchers has studied the genetics of pancreatic cancer, revealing it is actually four separate diseases, with different genetic triggers and survival rates, paving the way for more accurate diagnoses and treatments.

Contact: Nerissa Hannink
nhannink@unimelb.edu.au
61-430-588-055
University of Melbourne

Public Release: 23-Feb-2016
ACS Nano
New therapeutic pathway may keep cancer cells turned 'off'
A new Tel Aviv University study offers tangible evidence that it is possible to keep osteosarcoma lesions dormant using novel nanomedicines.

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University

Public Release: 23-Feb-2016
Journal of the National Cancer Institute
What are the benefits and harms of cancer screening? Most guidelines don't tell you
A new study finds most cancer screening guidelines do not clearly spell out the benefits and harms of the recommended actions.
VA Advanced Fellowship in Health Services Research & Development, Michigan Center for Diabetes Translational Research, National Institutes of Health, VA HSR&D Center of Innovation

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 23-Feb-2016
Small
DNA 'Trojan horse' smuggles drugs into resistant cancer cells
Drug-resistant leukemia cells absorb a drug and die, when the drug is hidden inside a capsule made of folded up DNA.
Leukemia and Lymphoma Society, National Cancer Institute

Contact: Pam Frost Gorder
Gorder.1@osu.edu
614-292-9475
Ohio State University

Public Release: 23-Feb-2016
Cancer Immunology Research
Genetically engineered immune cell therapy found to boost survival in mice with brain tumors
Nagoya University-led research team shows in mice the potential of a special immune cell that targets a key protein in tumor growth that helps stop brain cancer.
Japan Agency for Medical Research and Development

Contact: Koomi Sung
press@aip.nagoya-u.ac.jp
Nagoya University

Public Release: 23-Feb-2016
Frontiers in Oncology
Two forms of radiosurgery for brain metastases are equally effective
While two advanced radiosurgery approaches -- Gamma Knife and RapidArc® -- offer different strengths, they are equally effective at eradicating cancer in the brain, say researchers at Sidney Kimmel Cancer Center.
Sidney Kimmel Cancer Center, Varian Medical

Contact: Colleen Cordaro
colleen.cordaro@jefferson.edu
215-955-2238
Thomas Jefferson University

Showing releases 1001-1025 out of 1386.

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