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Showing releases 1026-1050 out of 1222.

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Public Release: 22-Nov-2013
American Journal of Hematology
Study finds link between allergies and increased risk of blood cancers in women
A team of scientists looking into the interplay of the immune system and cancer have found a link between a history of airborne allergies -- in particular to plants, grass and trees -- with risk of blood cancers in women.
NIH/National Cancer Institute

Contact: Kristen Woodward
Fred Hutchinson Cancer Research Center

Public Release: 22-Nov-2013
Cancer Epidemiology, Biomarkers & Prevention
Sugar-sweetened beverage consumption increases endometrial cancer risk
Postmenopausal women who consumed sugar-sweetened beverages were more likely to develop the most common type of endometrial cancer compared with women who did not drink sugar-sweetened beverages, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
NIH/National Cancer Institute

Contact: Jeremy Moore
American Association for Cancer Research

Public Release: 22-Nov-2013
Journal of Cancer
LSUHSC research finds combo of plant nutrients kills breast cancer cells
A study led by Madhwa Raj, Ph.D., Research Professor in Obstetrics and Gynecology at LSU Health Sciences Center New Orleans and its Stanley S. Scott Cancer Center, has found that a super cocktail of six natural compounds in vegetables, fruits, spices and plant roots killed 100 percent of sample breast cancer cells without toxic side effects on normal cells.

Contact: Leslie Capo
Louisiana State University Health Sciences Center

Public Release: 22-Nov-2013
Chemotherapy: When our intestinal bacteria provide reinforcement
Research jointly conducted by investigators at Institut Gustave Roussy, Inserm, Institut Pasteur and French National Agronomic Research Institute has led to a rather surprising discovery on the manner in which cancer chemotherapy treatments act more effectively with the help of the intestinal flora (also known as the intestinal microbiota).

Contact: Laurence Zitvogel
INSERM (Institut national de la santé et de la recherche médicale)

Public Release: 21-Nov-2013
Scientists show how cells protect their DNA from catastrophic damage
Researchers at the University of Copenhagen have unveiled a profound biological process that explains how DNA can be damaged during genome replication. In addition, the scientists developed a new analytical tool to measure the cell's response to chemotherapy, which could have an important impact on future cancer therapy. The results are now published in the scientific journal Cell.

Contact: Luis Ignacio Toledo
University of Copenhagen

Public Release: 21-Nov-2013
Molecular Cell
Targets of anticancer drugs have broader functions than what their name suggests
Drugs that inhibit the activity of enzymes called histone deacetylases (HDACs) are being widely developed for treating cancer and other diseases, with two already on the market. Researchers show that a major HDAC still functions in mice even when its enzyme activity is abolished, suggesting that the beneficial effects of HDAC inhibitors may not actually be through inhibiting HDAC activity, and thus warranting the reassessment of the molecular targets of this class of drugs.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 21-Nov-2013
The Lancet
Lowering 3 risk factors could cut obesity-related risk of heart disease by more than half
Controlling blood pressure, serum cholesterol, and blood glucose may substantially reduce the risk of heart disease and stroke associated with being overweight or obese.
Medical Research Council, National Institute for Health Research Comprehensive Biomedical Research Centre

Contact: Todd Datz
Harvard School of Public Health

Public Release: 21-Nov-2013
Journal of Wound Ostomy and Continence Nursing
Rutgers-Camden nursing scholar develops tool for ostomy care
Nurses caring for ostomy patients will now be equipped with an essential new tool developed by a Rutgers-Camden scholar that provides them with the first comprehensive guide to optimize ostomy management and enhance patient safety.

Contact: Ed Moorhouse
Rutgers University

Public Release: 21-Nov-2013
Researchers identify genomic variant associated with sun sensitivity, freckles
Researchers have identified a genomic variant strongly associated with sensitivity to the sun, brown hair, blue eyes -- and freckles. The study by an international team including researchers from the National Institutes of Health was reported in the Nov. 21, 2013, online edition of the journal Cell.
National Institutes of Health

Contact: Raymond MacDougall
NIH/National Human Genome Research Institute

Public Release: 21-Nov-2013
2 human proteins found to affect how 'jumping gene' gets around
Using a new method to catch elusive "jumping genes" in the act, researchers have found two human proteins that are used by one type of DNA to replicate itself and move from place to place. The discovery, described in the Nov. 21 issue of Cell, breaks new ground in understanding the arms race between a jumping gene and cells working to limit the risk posed by such volatile bits of DNA.
NIH/National Institute of General Medical Sciences

Contact: Shawna Williams
Johns Hopkins Medicine

Public Release: 21-Nov-2013
Research paves path for hybrid nano-materials that could replace human tissue or today's pills
A team of researchers has uncovered critical information that could help scientists understand how protein polymers interact with other self-assembling biopolymers. The research helps explain naturally occurring nano-material within cells and could one day lead to engineered bio-composites for drug delivery, artificial tissue, bio-sensing, or cancer diagnosis. The collaborative research was centered in the Polytechnic Institute of New York University Montclare Lab for Protein Engineering and Molecular Design.
National Science Foundation, Society of Plastics Engineers, Swiss National Science Foundation, Adolphe-Merkle Foundation

Contact: Kathleen Hamilton
New York University Polytechnic School of Engineering

Public Release: 21-Nov-2013
Journal of Cell Science
A study on cell migration provides insights into the movement of cancer cells
The migration of groups of cells in order to form tissues is common during the development of an organism. Discovering how these multiple movements are achieved is not only crucial to understand the basic principles of development but provides new information and insights for further research into processes associated with the spread of cancer.

Contact: Sònia Armengou
Institute for Research in Biomedicine (IRB Barcelona)

Public Release: 21-Nov-2013
Science Translational Medicine
UCLA researchers' new technique improves accuracy, ease of cancer diagnosis
A team of researchers from UCLA and Harvard University have demonstrated a technique, deformability cytometry, that measures the physical properties of individual cells and can diagnose cancer from body fluids with very high accuracy.

Contact: Matthew Chin
University of California - Los Angeles

Public Release: 21-Nov-2013
A hallmark for the development of testicular tumors found in the aberrant regulation of small non-coding RNA
Researchers from the Bellvitge Biomedical Research Institute in Barcelona, Spain, have studied the role of a peculiar class of small non-coding RNAs that are mainly expressed in the human male germline.

Contact: Andrew Thompson
Landes Bioscience

Public Release: 21-Nov-2013
Cancer Discovery
UCLA research could enhance treatments for drug-resistant melanoma
Drugs called BRAF inhibitors shrink most melanoma tumors quickly. Despite good responses, melanoma tumors do not shrink away completely. Left-behind cancer cells allow tumors to grow back drug resistant. Using multiple drugs that simultaneously target the different tumor resistance mechanisms may prevent drug resistance and tumor regrowth.

Contact: Shaun Mason
University of California - Los Angeles

Public Release: 21-Nov-2013
Cancer Discovery
SU2C researcher identifies potential treatment option for melanoma
Stand Up To Cancer, the charitable initiative supporting ground-breaking research to accelerate new cancer treatments, announces that the Allan H. (Bud) and Sue Selig Stand Up To Cancer Melanoma Innovative Research Grant Recipient Roger S. Lo, M.D., Ph.D., (Jonsson Comprehensive Cancer Center, UCLA) has published two studies in Cancer Discovery which indicate that treatment using combinatory therapy may be effective in suppressing drug resistance in the treatment of melanoma.
Stand Up To Cancer

Contact: Jane E. Rubinstein
Rubenstein Associates, Inc.

Public Release: 20-Nov-2013
Drug strategy blocks a leading driver of cancer
The protein in cells that most often drives the development of cancers has eluded scientists' efforts to block it for three decades -- until now.

Contact: Jeffrey Norris
University of California - San Francisco

Public Release: 20-Nov-2013
New England Journal of Medicine
International Tree Nut Council funded study links nut consumption to reduced death rate
In a study published today in the New England Journal of Medicine, researchers looked at the association of nut consumption with total and cause-specific mortality among 76,464 women in the Nurses' Health Study and 42,498 men in the Health Professionals Follow-up Study.
International Tree Nut Council Nutrition Research & Education Foundation

Contact: Maureen Ternus, M.S., R.D
Motion PR

Public Release: 20-Nov-2013
New England Journal of Medicine
Large study links nut consumption to reduced death rate
In the largest study of its kind, people who ate a daily handful of nuts were 20 percent less likely to die from any cause over a 30-year period than were those who didn't consume nuts, say scientists from Dana-Farber Cancer Institute, Brigham and Women's Hospital, and the Harvard School of Public Health.
International Tree Nut Council Nutrition Research & Education Foundation

Contact: Anne Doerr
Dana-Farber Cancer Institute

Public Release: 20-Nov-2013
Nature Structural & Molecular Biology
Spanish scientists identify a new ancestral enzyme that facilitates DNA repair
Researchers from the Spanish National Cancer Research Centre, led by Juan Mendez, head of the DNA Replication Group, together with Luis Blanco, from the Severo Ochoa Molecular Biology Centre, have discovered how a new human enzyme, the protein PrimPol, is capable of recognizing DNA lesions and facilitate their repair during the DNA copying process, thus avoiding irreversible and lethal damage to the cells and, therefore, to the organism.

Contact: Nuria Noriega
Centro Nacional de Investigaciones Oncologicas (CNIO)

Public Release: 20-Nov-2013
Nutrition and Cancer
Women prescribed combination HRT should use caution when taking apigenin supplement, MU study finds
In 2011, studies conducted by University of Missouri researchers found that a natural compound called apigenin, which is found in celery, parsley, and apples, could reduce the incidence of tumor growth in women receiving hormone replacement therapy. Now, based on subsequent studies conducted by MU researchers, they are recommending that women not ingest pure apigenin as a supplement.

Contact: Jeff Sossamon
University of Missouri-Columbia

Public Release: 20-Nov-2013
New crizotinib side-effect
A University of Colorado Cancer Center study published today in the journal Cancer shows that using crizotinib to treat ALK positive non-small cell lung cancer appears to reduce kidney function when assessed by one of the most commonly used clinical methods.
NIH/National Cancer Institute, National Institutes of Health

Contact: Garth Sundem
University of Colorado Denver

Public Release: 20-Nov-2013
World's leading lung societies unite to call for improvements in health care
Experts from the world's leading lung organizations have come together for the first time to call for a worldwide effort to improve health-care policies and systems and care delivery to make a positive difference for the lung health of the world. Produced by the Forum of International Respiratory Societies, the report has been launched today, on World COPD Day, providing an overview of lung health across the globe.

Contact: Kristi Bruno
American College of Chest Physicians

Public Release: 20-Nov-2013
EORTC head & neck cancer trial shows assessing HRQOL is valuable to both patients and their doctors
EORTC trial 24954 set out to compare two treatment schemes for patients with respectable hypopharyngeal and laryngeal cancers, and the results published in Cancer show that there is a trend towards worse HRQOL scores in patients receiving alternating chemoradiotherapy (alternating arm) as opposed to those given sequential induction chemotherapy and radiotherapy (sequential arm). However, very few differences reached the level of statistical significance, and most patients' HRQOL scores returned to baseline once treatment was completed.
NIH/National Cancer Institute, Fonds Cancer/FOCA, Belgium

Contact: John Bean
European Organisation for Research and Treatment of Cancer

Public Release: 20-Nov-2013
Linking risk factors and disease origins in breast cancer
Researchers from the Geisel School of Medicine at Dartmouth have found that epigenetic changes to DNA are associated with aging in disease-free breast tissues and are further altered in breast tumors. Epigenetic changes describe heritable alterations caused by mechanisms other than by changes in DNA sequence. The discovery, published in the Feb. 2014 issue of Epigenetics, illustrates how cancer and aging are tightly interconnected processes by identifying epigenetic alterations present in the normal aging breast that may increase disease risk in cancer-free individuals.

Contact: Andrew Thompson
Landes Bioscience

Showing releases 1026-1050 out of 1222.

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