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Public Release: 19-Nov-2013
Age affects short-term quality of life after breast biopsy
Breast biopsies can adversely affect short-term quality-of-life, and the effects are more pronounced in younger patients, according to a new study.
National Institutes of Health

Contact: Linda Brooks
Radiological Society of North America

Public Release: 19-Nov-2013
UT Dallas computer scientists create 3-D technique
UT Dallas computer scientists are using a famous mathematician's theory to make 3-D images that are more accurate approximations of the shapes of the original objects.

Contact: LaKisha Ladson
University of Texas at Dallas

Public Release: 19-Nov-2013
Biology Open
A CNIO study recreates the history of life through the genome
One of the most important processes in the life of cells is genome replication. In most organisms genome replication follows a set plan, in which certain regions of the genome replicate before others; alterations in the late replication phases had previously been related to cancer and aging. Now, a team from the Spanish National Cancer Research Centre has for the first time related this process to evolution of life.

Contact: Nuria Noriega
Centro Nacional de Investigaciones Oncologicas (CNIO)

Public Release: 19-Nov-2013
Cancer Epidemiology, Biomarkers & Prevention
Smoking increases risk of death for nasopharyngeal carcinoma survivors
Survivors of nasopharyngeal carcinoma who are former or current smokers are more likely to have their disease progress, relapse, or spread, and are more likely to die of their disease, compared with survivors of nasopharyngeal carcinoma who have never smoked, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
National Natural Science Foundation of China, Science Foundation of Key Hospital Clinical Program Ministry of Health China

Contact: Jeremy Moore
American Association for Cancer Research

Public Release: 19-Nov-2013
Clinical Cancer Research
Oral drug may improve survival in men with metastatic prostate cancer
An investigational prostate cancer treatment slows the disease's progression and may increase survival, especially among men whose cancer has spread to the bones, according an analysis led by the Duke Cancer Institute.
Active Biotech

Contact: Rachel Harrison
Duke University Medical Center

Public Release: 19-Nov-2013
American Journal of Preventive Medicine
Smartphone apps lack proven strategies to help smokers quit
An estimated 11 million smokers in the United States own a smartphone and increasingly they're turning to apps in an attempt to quit. But many of the most popular anti-smoking apps for iPhones or Androids lack some basic strategies that are known to help smokers quit, according to a new study in the American Journal of Preventive Medicine.

Contact: Kathy Fackelmann
George Washington University School of Public Health and Health Services

Public Release: 18-Nov-2013
Journal of Experimental Medicine
More than skin deep: New layer to the body's fight against infection
The layers of skin that form the first line of defense in the body's fight against infection have revealed a unanticipated secret. The single cell type that was thought to be behind the skin's immune defense has been found to have a doppelganger, with researchers from the Walter and Eliza Hall Institute showing the cells, despite appearing identical, are actually two different types.
Australian National Health and Medical Research Council, Victorian Government

Contact: Alan Gill
Walter and Eliza Hall Institute

Public Release: 18-Nov-2013
Manipulation of protein could help stop spread of cancer cells
Understanding how and why cancer cells move away from their original location is important to find ways to stop the spread of the disease. New findings, published in the Nature journal Oncogene, reveal how a protein, called "PRH," is normally able to prevent cells from unnecessary migration. It is likely that this protein is less effective in cancer cells allowing the cells to venture away.
Breast Cancer Campaign

Contact: Caroline Clancy
University of Bristol

Public Release: 18-Nov-2013
JAMA Internal Medicine
2 studies on the use of breast MRI
The overall use of breast magnetic resonance imaging has increased, with the procedure most commonly used for diagnostic evaluations and screenings, according to a study published by JAMA Internal Medicine, a JAMA Network publication.

Contact: Rebecca Hughes
The JAMA Network Journals

Public Release: 18-Nov-2013
Journal of the National Cancer Institute
Higher than normal levels of Vitamin B12 may indicate cancer risk
Vitamin B12 (cobalamin [Cbl]) is essential for maintaining healthy bodily function but higher than normal levels (reference range 200-600 pmol/L) may indicate that a patient is at risk of developing certain cancers, according to a study published November 18 in the Journal of the National Cancer Institute. Previous studies had suggested an association between high Cbl levels and specific cancers.

Contact: Zachary Rathner
Journal of the National Cancer Institute

Public Release: 18-Nov-2013
Annals of Internal Medicine
Embargoed news from Nov. 19, 2013 Annals of Internal Medicine tip sheet
Below is information about articles being published in Annals of Internal Medicine. The information is not intended to substitute for the full article as a source of information. Annals of Internal Medicine attribution is required for all coverage.

Contact: Megan Hanks
American College of Physicians

Public Release: 18-Nov-2013
JAMA Internal Medicine
High-risk women get breast MRI -- but room remains for improvement
Breast MRI is a new technology that is recommended, in addition to (less-expensive) mammography, for screening women at high lifetime risk for breast cancer. Two papers in JAMA Internal Medicine (one national from Group Health and one regional from Harvard) show that breast MRI is now being used for screening more often than for diagnosis; and for screening it is overused in average-risk women and underused in higher-risk women, but that pattern is improving.
NIH/National Cancer Institute, Agency for Healthcare Research and Quality

Contact: Rebecca Hughes
Group Health Research Institute

Public Release: 18-Nov-2013
Proceedings of the National Academy of Sciences
Gene plays major role in suppressing cancer
Adelaide researchers have found that a specific gene plays an important role in suppressing lymphoma, a type of blood cell cancer.
National Health and Medical Research Council

Contact: Sharad Kumar
University of Adelaide

Public Release: 18-Nov-2013
Cancer Prevention Research
Men with prostate cancer who ate a low-fat fish oil diet showed changes in their cancer tissue
Men with prostate cancer who ate a low-fat diet and took fish oil supplements had lower levels of pro-inflammatory substances in their blood and a lower cell cycle progression score, a measure used to predict cancer recurrence, than men who ate a typical Western diet, UCLA researchers found.
National Institutes of Health

Contact: Kim Irwin
University of California - Los Angeles Health Sciences

Public Release: 18-Nov-2013
Cancer Research
A study led by CNIO validates a new anti-cancer therapy based on cell division
A study led by Ignacio Pérez de Castro, a researcher in the Spanish National Cancer Research Centre's Cell Division and Cancer Group, and its Group Leader, Marcos Malumbres, describes the cellular consequences of genetically deleting Aurora-A, an important target for the development of new anti-cancer agents, in mouse models.

Contact: Nuria Noriega
Centro Nacional de Investigaciones Oncologicas (CNIO)

Public Release: 18-Nov-2013
Breast Cancer Research and Treatment
Obesity found to be major risk factor in developing basal-like breast cancer
Women who are obese face an increased risk of developing an aggressive sub-type of breast cancer known as "basal-like," according to research conducted at the University of North Carolina.

Contact: William Davis
University of North Carolina Health Care

Public Release: 18-Nov-2013
Journal of Clinical Oncology
Adult survivors of childhood cancer at risk of becoming frail at an early age
Young adults who survived childhood cancer are more likely than their peers to be frail, according to a St. Jude Children's Research Hospital study, which reported the condition is more common among female survivors than women decades older.
NIH/National Cancer Institute, American Lebanese Syrian Associated Charities

Contact: Summer Freeman
St. Jude Children's Research Hospital

Public Release: 18-Nov-2013
Functional & Integrative Genomics
Mutations of immune system found in breast cancers
Mutations in the genes that defend the body against cancer-related viruses and other infections may play a larger role in breast cancer than previously thought, according to a study at the University of Illinois at Chicago.

Contact: Sharon Parmet
University of Illinois at Chicago

Public Release: 18-Nov-2013
Journal of Women's Health
Calcium plus vitamin D supplementation does not reduce risk of hip fracture or colorectal cancer
New results are in from the Women's Health Initiative Calcium plus Vitamin D Supplementation Trial. These findings assess the effects on hip fracture and colorectal cancer incidence among 30,000 postmenopausal women nearly five years after the seven-year period of calcium plus vitamin D supplementation ended.

Contact: Vicki Cohn
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 17-Nov-2013
Nature Methods
Protein coding 'junk genes' may be linked to cancer
By using a new analysis method, researchers at Karolinska Institutet and Science for Life Laboratory in Sweden have found close to one hundred novel human gene regions that code for proteins. A number of these regions are so-called pseudogenes, which may be linked to cancer.
Swedish Research Council, Swedish Cancer Society, EU FP7 project GlycoHit, and others

Contact: The Press Office
Karolinska Institutet

Public Release: 17-Nov-2013
Genome Research
Scientists fingerprint single cancer cells to map cancer's family tree
Scientists at The Institute of Cancer Research, London, have used a DNA sequencing technique to identify mutations present across thousands of cancer cells in three patients with leukemia. The technique can identify the founding mutations from which a tumor evolved and uses computer software to map the cancer's family tree. The findings could be used to identify the key mutations that occur early in a tumor's development, allowing doctors to use targeted treatments more effectively.
Leukaemia and Lymphoma Research, Kay Kendall Leukaemia Fund, The Institute of Cancer Research

Contact: Graham Shaw
Institute of Cancer Research

Public Release: 17-Nov-2013
Cell Cycle
Novel study charts aggressive prostate cancer
Many patients diagnosed with prostate cancer have indolent, slow-growing forms of the disease that are not life-threatening. However, more than 30,000 American men will die from aggressive prostate cancer this year alone. This sharp contrast between low-risk and aggressive disease presents a challenge for many researchers and physicians as they diagnose patients and also determine the prognosis of the men with the most aggressive forms of prostate cancer.
Steven Spielberg Discovery Fund, NIH/National Cancer Institute

Contact: Cara Lasala
Cedars-Sinai Medical Center

Public Release: 15-Nov-2013
5th European Multidisciplinary Meeting for Urological Cancer (EMUC)
Italian study examines clinical predictors of acute urinary symptoms after radiotherapy for prostate
An interim study by Italian researchers showed that using a modelling program together with IPSS and dosage measure can predict the severity of acute urinary symptoms in patients with early prostate cancer who underwent radiotherapy.

Contact: Evgenia Starkova
European Association of Urology

Public Release: 15-Nov-2013
Drug offers promising approach to improve outcome for children with high-risk leukemia
Combining the drug gemtuzumab ozogamicin with conventional chemotherapy may improve the outcome of bone marrow transplantation for some children battling high-risk acute myeloid leukemia, according to a study led by St. Jude Children's Research Hospital.
NIH/National Cancer Institute, National Institutes of Health, American Lebanese Syrian Associated Charities

Contact: Summer Freeman
St. Jude Children's Research Hospital

Public Release: 15-Nov-2013
Clinical Epidemiology
Chronic diseases hinder good cancer survival rates
For bowel cancer patients with several other diseases, the one-year survival rate is 46 percent. For those without other diseases it is 80 percent. The same disparity characterizes other major types of cancer, shows new research based on figures from the Central Denmark Region.
Danish Cancer Society

Contact: Henrik Toft Sørensen
Aarhus University

Showing releases 1026-1050 out of 1249.

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