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Showing releases 1051-1075 out of 1239.

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Public Release: 20-May-2014
Research identifies genetic alterations in lung cancers that help select treatment
Multiplexed testing of lung cancer tumors identified genetic alterations that were helpful in selecting targeted treatments. Patients that received matched therapy for lung cancer lived longer than patients who did not receive directed therapy, although randomized clinical trials are required to determine if this treatment strategy improves survival, according to a study in the May 21 issue of JAMA.

Contact: Melissa Morgenweck
The JAMA Network Journals

Public Release: 20-May-2014
Nicotine and Tobacco Research
Students swayed by 'relaxing, fun' image of hookah smoking ignore health harms
Educational campaigns meant to dissuade college students from initiating hookah tobacco smoking may be more successful if they combat positive perceptions of hookah use as attractive and romantic, rather than focusing solely on the harmful components of hookah tobacco smoke, a new University of Pittsburgh School of Medicine study found.
NIH/National Cancer Institute, Steven Manners Memorial Fund

Contact: Allison Hydzik
University of Pittsburgh Schools of the Health Sciences

Public Release: 20-May-2014
American Society for Microbiology 114th General Meeting
More than two-thirds of healthy Americans are infected with human papilloma viruses
In what is believed to be the largest and most detailed genetic analysis of its kind, researchers at NYU Langone Medical Center and elsewhere have concluded that 69 percent of healthy American adults are infected with one or more of 109 strains of human papillomavirus.

Contact: David March
NYU Langone Medical Center / New York University School of Medicine

Public Release: 20-May-2014
Genomic tumor testing to match lung cancer patients with targeted drugs transforms care
New data from a study led by Memorial Sloan Kettering physicians that used targeted therapy for patients with the most common type of lung cancer has helped transform treatment for the disease.
NIH/National Cancer Institute

Contact: Melissa Morgenweck
Memorial Sloan-Kettering Cancer Center

Public Release: 20-May-2014
Study shows how streptococcal bacteria can be used to fight colon cancer
Researchers at Western University have shown how the bacteria primarily responsible for causing strep throat can be used to fight colon cancer. By engineering a streptococcal bacterial toxin to attach itself to tumor cells, they are forcing the immune system to recognize and attack the cancer. The study found the engineered bacterial toxin could significantly reduce the size of human colon cancer tumors in mice, with a drastic reduction in the instances of metastasis.
Canadian Institutes of Health Research

Contact: Kathy Wallis
519-661-2111 x81136
University of Western Ontario

Public Release: 20-May-2014
Molecular Cancer Therapeutics
Pine bark substance could be potent melanoma drug
A substance that comes from pine bark is a potential source for a new treatment of melanoma, according to Penn State College of Medicine researchers.
National Institutes of Health, Foreman Foundation for Melanoma Research, H.G. Barsumian, M.D. Memorial Fund

Contact: Matt Solovey
Penn State

Public Release: 20-May-2014
American Urological Association Annual Meeting
Prolaris test predicts mortality risk in prostate cancer biopsy study
Data presented at AUA 2014 show the Prolaris test accurately predicted mortality risk from prostate cancer within 10 years in patients diagnosed with needle biopsy. The use of this test could improve treatment for patients at all risk levels based on each man's personal risk of disease progression. Prolaris has been proven to predict prostate cancer-specific disease progression in 11 clinical trials with more than 6,000 patients.

Contact: Ronald Rogers
Myriad Genetics, Inc.

Public Release: 19-May-2014
Annals of Internal Medicine
Study calls for revisiting cardiac screening guidelines for survivors of childhood cancer
One of the first studies to analyze the effectiveness of screening survivors of childhood cancer for early signs of impending congestive heart failure finds improved health outcomes but suggests that less frequent screening than currently recommended may yield similar clinical benefit. The researchers, in a study published in the Annals of Internal Medicine, utilized a simulation-based model to estimate the long-term benefits associated with routine screening.
NIH/National Cancer Institute

Contact: Irene Sege
Dana-Farber Cancer Institute

Public Release: 19-May-2014
Journal of Urology
Low risk prostate cancer not always low risk
Selection of men for active surveillance should be based not on the widely used conventional biopsy, but with a new, image-guided targeted prostate biopsy.
NIH/National Cancer Institute

Contact: Kim Irwin
University of California - Los Angeles Health Sciences

Public Release: 19-May-2014
Annals of Internal Medicine
Tip sheet from Annals of Internal Medicine May 20, 2014
The May 20 issue of Annals of Internal Medicine includes articles titled: 'Task Force finds insufficient evidence to recommend for or against screening for suicide risk'; 'Vaccination during 'optimal window' is the key to saving lives and money in next flu pandemic'; and 'Two separate studies suggest that longer echocardiographic screening intervals for childhood cancer survivors effective, cost-effective for detecting heart issues.'

Contact: Megan Hanks
American College of Physicians

Public Release: 19-May-2014
American Urological Association Annual Meeting
Robot-assisted prostate cancer surgery as safe but more expensive as open surgery in older men
Minimally invasive robot-assisted surgery, which has become the main choice for surgically removing cancerous prostate glands during recent years, is as safe as open surgery for Medicare patients over age 65. Those are the primary findings of a newly published nationwide patient survey that included participation by researchers at Henry Ford Hospital, a pioneer of robot-assisted radical prostatectomy.

Contact: Dwight Angell
Henry Ford Health System

Public Release: 19-May-2014
Angewandte Chemie
Scripps Research Institute chemists discover structure of cancer drug candidate
Chemists at The Scripps Research Institute have determined the correct structure of a highly promising anticancer compound approved by the US Food and Drug Administration for clinical trials in cancer patients. The new report, published this week by the international chemistry journal Angewandte Chemie, focuses on a compound called TIC10.
Skaggs Institute for Chemical Biology, Scripps Research Institute

Contact: Mika Ono
Scripps Research Institute

Public Release: 19-May-2014
Journal of Clinical Oncology
A call to arms in cancer research
The rapid growth in the Hispanic population in the US is not matched by growth in Hispanics participating in cancer clinical trials -- not even close. Given the health disparities experienced by this population it is crucial that cancer researchers include more Hispanics in their trials, and there are steps they can take to do so, in an analysis from the Cancer Therapy & Research Center at the UT Health Science Center San Antonio.
NIH/National Cancer Institute

Contact: Elizabeth Allen
University of Texas Health Science Center at San Antonio

Public Release: 18-May-2014
American Society for Microbiology 114th General Meeting
Bacteria in mouth may diagnose pancreatic cancer
Patients with pancreatic cancer have a different and distinct profile of specific bacteria in their saliva compared to healthy controls and even patients with other cancers or pancreatic diseases, according to research presented today at the annual meeting of the American Society for Microbiology. These findings could form the basis for a test to diagnose the disease in its early stages.

Contact: Jim Sliwa
American Society for Microbiology

Public Release: 18-May-2014
Nano Letters
One small chip -- one giant leap forward for early cancer detection
An international team of researchers, led by ICFO- Institute of Photonic Sciences in Castelldefels, announce the successful development of a 'lab-on-a-chip' platform capable of detecting protein cancer markers in the blood using the very latest advances in plasmonics, nano-fabrication, microfluids and surface chemistry. The device is able to detect very low concentrations of protein cancer markers in blood, enabling diagnoses of the disease in its earliest stages.

Contact: Alina Hirschmann
ICFO-The Institute of Photonic Sciences

Public Release: 16-May-2014
Cancer Epidemiology, Biomarkers & Prevention
Analysis finds wide variation in lung cancer rates globally
The only recent comprehensive analysis of lung cancer rates for women around the world finds lung cancer rates are dropping in young women in many regions of the globe, pointing to the success of tobacco control efforts.
American Cancer Society

Contact: David Sampson
American Cancer Society

Public Release: 16-May-2014
MicroRNA that could be used to suppress prostate cancer progression found
About one in seven men will develop prostate cancer over the course of a lifetime, and about one in 36 men will die from it. This is why findings by Cincinnati Cancer Center researchers, showing that a tumor suppressive microRNA, when activated by an anti-estrogen drug, could contribute to development of future targeted therapies, are important.
Hong Kong University, Chinese University of Hong Kong, NIH/National Cancer Institute, VA, AstraZeneca

Contact: Katie Pence
University of Cincinnati Academic Health Center

Public Release: 16-May-2014
Cancer Epidemiology, Biomarkers & Prevention
Water pipe smoking causes significant exposure to nicotine and cancer-causing agents
Young adults who smoked water pipes in hookah bars had elevated levels of nicotine, cotinine, tobacco-related cancer-causing agents, and volatile organic compounds in their urine, and this may increase their risk for cancer and other chronic diseases, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
National Institutes of Health, California Tobacco-related Disease Research Program

Contact: Jeremy Moore
American Association for Cancer Research

Public Release: 16-May-2014
Journal of the National Cancer Institute
Herpes-loaded stem cells used to kill brain tumors
Harvard Stem Cell Institute scientists at Massachusetts General Hospital have a potential solution for how to more effectively kill tumor cells using cancer-killing viruses. The investigators report that trapping virus-loaded stem cells in a gel and applying them to tumors significantly improved survival in mice with glioblastoma multiform, the most common brain tumor in human adults and also the most difficult to treat.
James S. McDonnell Foundation, National Institutes of Health

Contact: Joseph Caputo
Harvard University

Public Release: 16-May-2014
American Psychosomatic Society Meeting
Cognitive behavioral or relaxation training helps women reduce distress during breast cancer treatment
Can psychological intervention help women adapt to the stresses of breast cancer? It appears that a brief, five-week psychological intervention can have beneficial effects for women who are dealing with the stresses of breast cancer diagnosis and surgery. Intervening during this early period after surgery may reduce women's distress and providing cognitive or relaxation skills for stress management to help them adapt to treatment.

Contact: Annette Gallagher
University of Miami

Public Release: 16-May-2014
Journal of Clinical Investigation
JCI online ahead of print table of contents for May 16, 2014
This release contains summaries, links to PDFs, and contact information for the following newsworthy papers published online, May 16, 2014 in the JCI: 'Targeting microbial translocation attenuates SIV-mediated inflammation,' 'Estrogen underlies sex-specific responses to sildenafil,' 'Vaccine-induced cell population inhibits SIV vaccine efficacy,' 'Enhancing efficacy of the cancer drug cetuximab,' 'Beta-catenin-regulated myeloid cell adhesion and migration determine wound healing,' 'Elevated sphingosine-1-phosphate promotes sickling and sickle cell disease progression,' and more.

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 15-May-2014
ASCO 50th Annual Meeting
Getting chemo first may help in rectal cancer
A new phase II study to be presented at the annual meeting of the American Society for Clinical Oncology finds that if chemotherapy is offered before radiation and surgery, more patients will be able to tolerate it and receive a full regimen of treatment.
Brown University

Contact: David Orenstein
Brown University

Public Release: 15-May-2014
Anticancer Research
Cancer's potential on-off switch
A team of Boston University School of Medicine researchers have proposed that an 'on and off' epigenetic switch could be a common mechanism behind the development of different types of cancer. Epigenetics is the phenomena whereby genetically identical cells express their genes differently, resulting in different physical traits. Researchers from the Boston University Cancer Center recently published two articles about this in Anticancer Research and Epigenomics.

Contact: Jenny Eriksen Leary
Boston University Medical Center

Public Release: 15-May-2014
Nature Photonics
Going beyond the surface
The new tech involves using near-infrared beams of light that, upon penetrating deep into the body, are converted into visible light that activates the drug and destroys the tumor.
Air Force of Scientific Research

Contact: Cory Nealon
University at Buffalo

Public Release: 15-May-2014
Nature Structural & Molecular Biology
Detailed studies reveal how key cancer-fighting protein is held in check
St. Jude Children's Research Hospital scientists have mapped the structural details of how p53 attaches to its regulatory protein, called BCL-xL, in the cell. The protein p53 is a key activator of the cell's protective machinery against genetic damage, such as the mutations that drive cancer cells' explosive growth.
National Institutes of Health, NIH/National Cancer Institute, American-Lebanese-Syrian Associated Charities

Contact: Summer Freeman
St. Jude Children's Research Hospital

Showing releases 1051-1075 out of 1239.

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