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Public Release: 12-May-2015
U-M researchers take step toward bringing precision medicine to all cancer patients
Researchers have developed and tested a new tool that searches for the most common genetic anomalies seen in cancer. The assay demonstrates the ability to make gene sequencing easier over a large volume of samples.
Evans Foundation/Prostate Cancer Research Foundation, National Institutes of Health, US Department of Defense, Life Technologies/Thermo Fisher Scientific, Stand Up to Cancer-Prostate Cancer Foundation, A. Alfred Taubman Medical Research Institute

Contact: Nicole Fawcett
University of Michigan Health System

Public Release: 12-May-2015
Significant progress made towards individualized cancer immunotherapy
Mainz-based researchers have made significant advances with regard to the development of individualized immunotherapy strategies for treating cancer. They have managed to identify the relevant genetic changes or mutations associated with various types of cancer and have determined their individual blueprints. This makes it possible for the scientists to readily produce customized cancer vaccines of the kind that have already been demonstrated to be effective in animal models.

Contact: Dr. Reneé Dillinger-Reiter
Johannes Gutenberg Universitaet Mainz

Public Release: 12-May-2015
Environmental Science and Technology
Fracking may affect air quality and human health
People living or working near active natural gas wells may be exposed to certain pollutants at higher levels than the Environmental Protection Agency considers safe for lifetime exposure. Air pollution from fracking operations may pose an under-recognized health hazard to people living near them, the researchers concluded.
NIH/National Institute of Environmental Health Sciences

Contact: Kim Anderson
Oregon State University

Public Release: 12-May-2015
American Journal of Preventive Medicine
Inconsistent Medicaid expansion would widen disparities in screenings for women's cancers
Virginia Commonwealth University Massey Cancer Center researchers recently conducted a study that found low-income and uninsured women in states that are not expanding their Affordable Care Act (ACA) Medicaid coverage are less likely to receive breast and cervical cancer screenings compared to states that are implementing expansions.
National Institutes of Health, NIH/National Cancer Institute, Office of Behavioral and Social Sciences Research, VCU Massey Cancer Center

Contact: Stevi Antosh
Virginia Commonwealth University

Public Release: 12-May-2015
MRI shows potential to improve breast cancer risk prediction
Magnetic resonance imaging (MRI) provides important information about a woman's future risk of developing breast cancer, according to a new study. Researchers said the findings support an expanded role for MRI in more personalized approaches to breast cancer screening and prevention.
National Institutes of Health

Contact: Linda Brooks
Radiological Society of North America

Public Release: 12-May-2015
Mid-America Orthopaedic Association Annual Meeting
Survival from rare bone cancer remains low
Among the deadliest cancers is a rare malignancy called mesenchymal chondrosarcoma, which begins in cartilage around bones and typically strikes young adults. Ten-year survival has been reported to be as low as 20 percent. But a Loyola study has found survival is not as dismal as prior reports. Fifty-one percent of patients survived at least five years, and 43 percent survived at least 10 years.

Contact: Jim Ritter
Loyola University Health System

Public Release: 12-May-2015
Journal of Biomedical Optics
Dartmouth team devises use of food dye, near infrared light to aid in breast resection
Investigators at t Dartmouth's Thayer School of Engineering and Norris Cotton Cancer Center devised a novel approach to perform near infrared (NIR) optical measurements of resected breast tissue after the margins have had their traditional marking by the surgeon to preserve information about their orientation for potential follow-up surgeries.
NIH/National Cancer Institute, National Institutes of Health

Contact: Kirk Cassels
The Geisel School of Medicine at Dartmouth

Public Release: 12-May-2015
Cancer Research
siRNA-toting nanoparticles inhibit breast cancer metastasis
Researchers at Case Western Reserve University combined finely crafted nanoparticles with one of nature's potent disrupters to prevent the spread of triple-negative breast cancer in mouse models. The researchers are working toward clinical trials and exploring use of the technology for other cancers and diseases.
National Institutes of Health, National Science Foundation, US Department of Defense

Contact: Kevin Mayhood
Case Western Reserve University

Public Release: 11-May-2015
Advanced viral gene therapy eradicates prostate cancer in preclinical experiments
Even with the best available treatments, the median survival of patients with metastatic, hormone-refractory prostate cancer is only two to three years. Driven by the need for more effective therapies for these patients, researchers at VCU Massey Cancer Center and the VCU Institute of Molecular Medicine have developed a unique approach that uses microscopic gas bubbles to deliver directly to the cancer a viral gene therapy in combination with an experimental drug that targets a specific gene driving the cancer's growth.
NIH/National Cancer Institute, US Department of Defense, National Foundation for Cancer Research, VCU Massey Cancer Center

Contact: John Wallace
Virginia Commonwealth University

Public Release: 11-May-2015
Journal of Clinical Oncology
Men with high estrogen levels could be at greater risk of breast cancer
Men with naturally high levels of the female hormone estrogen may have a greater risk of developing breast cancer.
Cancer Research UK, NIH/National Cancer Institute, Deutsche Krebshilfe, Deutsches Krebforschungszentrum, German Federal Ministry of Education and Research, Swedish Cancer Society, Swedish Scientific Council, Regional Government of Skå

Contact: Emily Head
Cancer Research UK

Public Release: 11-May-2015
Journal of the American Board of Family Medicine
Patients more likely to get HPV vaccine after electronic health record prompts
The HPV vaccine has the lowest completion rates of any other vaccine. New study shows that reminders via electronic health records may help improve rates.
NIH/National Cancer Institute

Contact: Beata Mostafavi
University of Michigan Health System

Public Release: 11-May-2015
Journal of Cell Biology
Leicester research team identifies potential new targets for cancer treatments
Research papers identify key steps in cell division -- and potential to inhibit cancer cell division.
Worldwide Cancer Research, Cancer Research UK, Wellcome Trust, Biotechnology and Biological Sciences Research Council, Medical Research Council, Hope Against Cancer

Contact: Andrew Fry
University of Leicester

Public Release: 11-May-2015
Cancer Cell
Study may suggest new strategies for myelodysplastic syndromes treatment
A study revealing fresh insight about chromosome 'tails' called telomeres may provide scientists with a new way to look at developing treatments or even preventing a group of blood cell disorders known as myelodysplastic syndromes.

Contact: Ron Gilmore
University of Texas M. D. Anderson Cancer Center

Public Release: 11-May-2015
Journal of Clinical Oncology
Breast cancer patients 60+ with luminal A subtype may not need radiation if on hormone therapy
Women with luminal A subtype breast cancer -- and particularly those older than 60 -- may not need radiation treatment if they are already taking hormone therapy, shows clinical research led by radiation oncologists at the Princess Margaret Cancer Centre published online today in the Journal of Clinical Oncology.

Contact: Jane Finlayson
University Health Network

Public Release: 11-May-2015
How cancer tricks the lymphatic system into spreading tumors
Cancer researchers and immunologists at Sweden's Karolinska Institutet have discovered how cancer cells can infiltrate the lymphatic system by 'disguising' themselves as immune cells (white blood cells).
Swedish Research Council, Swedish Cancer Society, Children's Cancer Foundation, Swedish Society for Medical Research, Karolinska Institutet, Nordic Cancer Union

Contact: KI Press Office
Karolinska Institutet

Public Release: 11-May-2015
Nature Biotechnology
Using CRISPR, biologists find a way to comprehensively identify anti-cancer drug targets
Imagine having a complete catalog of the best drug targets to hit in a deadly form of cancer. Imagine having a master catalog of such targets for all major cancers. Scientists at CSHL have published a method of doing precisely this, using the revolutionary gene-editing technology called CRISPR.
National Institutes of Health, Burroughs-Wellcome Fund, Alex's Lemonade Stand Foundation, National Cancer Center, Simons Center for Quantitative Biology

Contact: Peter Tarr
Cold Spring Harbor Laboratory

Public Release: 11-May-2015
Nature Communications
Dying cells can protect their stem cells from destruction
Cells dying as the result of radiation exposure or chemotherapy can send a warning to nearby stem cells or to tumor-initiating cells. The chemical signal allows both the tissue-repair cells and the tumor-forming cells to escape the same fate. This may explain why many cancers return after initially responding to treatment and could lead to new, more effective cancer drugs. These might block the warning signal that stops the cells from going into programmed cell death.
American Heart Association, Western State Affiliate Postdoctoral Fellowship, National Institutes of Health

Contact: Leila Gray
University of Washington Health Sciences/UW Medicine

Public Release: 11-May-2015
Cancer Cell
First cancer-promoting oncogenes discovered in rare brain tumor of children and adults
Researchers have identified three genes that play a pivotal role in the brain tumor choroid plexus carcinoma, a discovery that lays the groundwork for more effective treatment of this rare, often fatal cancer. St. Jude Children's Research Hospital scientists led the study, which appears today in the journal Cancer Cell.
National Institutes of Health, US Department of Defense, and ALSAC

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Public Release: 11-May-2015
Journal of National Cancer Institute
80 percent of cervical cancers found to be preventable with latest 9-valent HPV vaccine
The newest human papillomavirus vaccine, 9-Valent, can potentially prevent 80 percent of cervical cancers in the United States if given to all 11- or 12-year-old children before they are exposed to the virus.
US Centers for Disease Control and Prevention, National Institutes of Health, California Department of Health Services, and others

Contact: Cara Martinez
Cedars-Sinai Medical Center

Public Release: 11-May-2015
Journal of the National Cancer Institute
Combined radiation and hormonal therapy improves survival in node-positive prostate cancer
A new study finds that men with prostate cancer that has spread to nearby lymph nodes can benefit from the addition of radiation therapy to treatments that block the effects of testosterone. The findings imply that the almost half of patients with node-positive disease nationwide who this study found had not received combination therapy were not receiving the treatment that could best control their tumor and possibly save their lives.
American Cancer Society, Prostate Cancer Foundation

Contact: Katie Marquedant
Massachusetts General Hospital

Public Release: 11-May-2015
Childhood cancer treatment and age influence obesity risk for childhood cancer survivors
Childhood cancer survivors -- especially those whose treatment included brain irradiation or chemotherapy with glucocorticoids -- are 14 percent more likely to be obese than their healthy peers. The St. Jude Children's Research Hospital study appears today in the journal Cancer.
NIH/National Cancer Institute, ALSAC

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Public Release: 11-May-2015
Nature Communications
Gene found that is essential to maintaining breast and cancer stem cells
The gene and hormone soup that enables women to breastfeed their newborns also can be a recipe for breast cancer, particularly when the first pregnancy is after age 30.

Contact: Toni Baker
Medical College of Georgia at Georgia Regents University

Public Release: 11-May-2015
American Journal of Epidemiology
Study links father's age and risk of blood cancer as an adult
A new study links a father's age at birth to the risk that his child will develop blood and immune system cancers as an adult, particularly for only children.
American Cancer Society

Contact: David Sampson
American Cancer Society

Public Release: 11-May-2015
Journal of Nutritional Biochemistry
New Harvard research finds walnuts may help slow colon cancer growth
New Harvard research finds walnuts may help slow colon cancer growth. A walnut-enriched diet may cause beneficial genetic changes in animal cancer cells, affecting inflammation, blood supply and growth of tumors.
California Walnut Commission, American Institute for Cancer Research

Contact: Erin Farkaly
Edelman Seattle

Public Release: 11-May-2015
Physical Review Letters
A turning point in the physics of blood
In a paper published May 1, 2015, in the journal Physical Review Letters, Professor Mike Graham and Ph.D. students Kushal Sinha and Rafael G. Henríquez Rivera lay out an equation that yields simple predictions as to how quickly blood cells will migrate away from blood-vessel walls, how they will behave when they collide with each other and accordingly how they will segregate during flow.

Contact: Mike Graham
University of Wisconsin-Madison

Showing releases 1051-1075 out of 1336.

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