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Showing releases 1051-1075 out of 1212. << < 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 > >>
Public Release: 28-Feb-2013
 Applied Physiology, Nutrition and MetabolismGrape seed and skin extract – a weapon in the fight against kidney disease caused by high-fat diets New insight into grape seed extract as a therapeutic and preventative measure to fight obesity-induced kidney damage is presented in a new study. Grape seed and skin extract (GSSE) is known to contain powerful antioxidants. This study, published in the journal Applied Physiology, Nutrition, and Metabolism, is the first to make a link between GSSEs and high-fat-diet-induced renal disease. Contact: Jenny Ryan
Public Release: 28-Feb-2013
CellStudy identifies growth factor essential to the most common malignant pediatric brain tumor A multi-institutional team has identified a molecular pathway that appears to be essential for the growth and spread of medulloblastoma, the most common malignant brain tumor in children. In their report they show that blocking this pathway leads to regression of all four molecular subtypes of medulloblastoma in several mouse models. 
National Institutes of Health, Hoffmann-La Roche
Contact: Katie Marquedant
Public Release: 28-Feb-2013
ScienceMIMR researchers find a protein link to STI susceptibility Monash Institute of Medical Research scientists have found a protein in the female reproductive tract that protects against sexually transmitted diseases such as chlamydia and herpes simplex virus. Contact: Caroline Page
Public Release: 28-Feb-2013
Cancer Epidemiology, Biomarkers & PreventionPhysical activity does not protect against in situ breast cancer Non-invasive, or in situ breast cancer, is characterized by the fact that it does not invade or does not multiply in other cells. Unlike invasive breast cancer, it is not benefited by physical exercise. The experts suggest that exercise would only have protective effects once the tumor starts to invade the breast tissue. Contact: Press Office
Public Release: 28-Feb-2013
Plastic and Reconstructive SurgeryRound or 'shaped,' implants yield good results in breast reconstruction For women undergoing breast reconstruction using implants, most patient-reported outcomes are similar with two different shapes of silicone gel-filled implants, reports a study in the March issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons. Contact: Connie Hughes
Public Release: 27-Feb-2013
Journal of Biological ChemistryCell sugar concentrations affect hyaluronan production and cancer growth According to a recent University of Eastern Finland study, elevated cell sugar concentrations increase the production of hyaluronan which, in turn, promotes cancer growth. Regulating the production of hyaluronan may be a way to prevent the spreading of cancer. Contact: Kirsi Rilla
Public Release: 27-Feb-2013
Science Translational MedicineInfusion of stem cells and specially generated T-cells from same donor improves leukemia survival In a significant advance for harnessing the immune system to treat leukemias, researchers at Fred Hutchinson Cancer Research Center for the first time have successfully infused large numbers of donor T-cells specific for a key anti-leukemic antigen to prolong survival in high-risk and relapsed leukemia patients after stem cell transplantation. Both the stem cells for transplant and the T-cells came from the same matched donors.
NIH/National Cancer Institute, Leukemia and Lymphoma Society
Contact: Dean Forbes
Public Release: 27-Feb-2013
Cancer ResearchNew cancer 'vaccine' shows future promise in treating and preventing metastatic cancers Preclinical, laboratory studies suggest a novel immunotherapy could potentially work like a vaccine against metastatic cancers, according to scientists at Virginia Commonwealth University Massey Cancer Center. Results from a recent study show the therapy could treat metastatic cancers and be used in combination with current cancer therapies.
NIH/National Cancer Institute, National Institutes of Health
Contact: John Wallace
Public Release: 27-Feb-2013
Cochrane LibrarySpinal cancer: Guidelines for diagnosis unsupported in patients with lower back pain A new systematic review published in The Cochrane Library has raised doubts as to the effectiveness of "red flag" indicators at both identifying and excluding cancer in patients with lower back pain. The authors of the review concluded that most individual red flags were poor at diagnosing spinal malignancies and call for further studies focused on combinations of red flags. Contact: Jennifer Beal
Public Release: 27-Feb-2013
Canadian Journal of Public HealthCanadian adult obesity at historic high Obesity rates across Canada are reaching alarming levels and continue to climb, according to a new University of British Columbia study. Contact: Jennifer Parisi
Public Release: 27-Feb-2013
Chemical ScienceResearch update: Chemists find help from nature in fighting cancer Study of several dozen compounds based on a fungal chemical shows potent anti-tumor activity.
NIH/National Institute of General Medical Sciences
Contact: Sarah McDonnell
Public Release: 27-Feb-2013
Proceedings of the National Academy of SciencesChanging shape makes chemotherapy drugs better at targeting cancer cells Bioengineering researchers at University of California, Santa Barbara have found that changing the shape of chemotherapy drug nanoparticles from spherical to rod-shaped made them up to 10,000 times more effective at specifically targeting and delivering anti-cancer drugs to breast cancer cells.
Genentech, University of California Discovery Program, Errett Discovery Award in Biomedical Research
Contact: Melissa Van De Werfhorst
Public Release: 27-Feb-2013
Developmental CellProtein balance key in preventing cancer Two proteins that scientists once thought carried out the same functions are actually antagonists of each other, and keeping them in balance is key to preventing diseases such as cancer, according to new findings published in the Feb. 25 issue of Developmental Cell by scientists at Fox Chase Cancer Center. The results suggest that new compounds could fight cancer by targeting the pathways responsible for maintaining the proper balance between the proteins. Contact: Diana Quattrone
Public Release: 27-Feb-2013
CancerSurgery and radiation improve survival for metastatic gastric cancer patients, Moffitt study shows Researchers at Moffitt Cancer Center studied patients with metastatic gastric cancer and found that those who have both surgery and radiation have better survival than those who receive one or no form of treatment. Contact: Kim Polacek
Public Release: 27-Feb-2013
Journal of Animal ScienceSwine cells could power artificial liver Scientists are examining a line of "immortal" swine cells that can differentiate into liver cells. These cells could be part of an artificial liver device, which could reduce the need for liver transplants. Contact: Madeline McCurry-Schmidt
Public Release: 26-Feb-2013
JAMAStudy finds small increase in incidence of advanced breast cancer among younger women An analysis of breast cancer trends in the US finds a small but statistically significant increase in the incidence of advanced breast cancer for women 25 to 39 years of age, without a corresponding increase in older women, according to a study appearing in the Feb. 27 issue of JAMA. Contact: Alyse Bernal
Public Release: 26-Feb-2013
Cancer ResearchObesity, physical inactivity linked with risk for certain molecular subtype of colorectal cancer Obesity increased risk; physical activity lowered risk. Data consistent with prior research linking exercise to decreased mortality. Research on colon cancer should incorporate heterogeneity of disease. Contact: Jeremy Moore
Public Release: 26-Feb-2013
CellTarget: Cancer A microscopy technique developed at the University of Akron could be key to improving cancer treatments with targeted therapeutic drugs.
NIH/National Cancer Institute, Howard Hughes Medical Institute, US Department of Energy
Contact: Denise Henry
Public Release: 26-Feb-2013
Cancer ResearchU-M study challenges notion of using Herceptin only for HER2-positive breast cancer New research from the University of Michigan Comprehensive Cancer Center finds that the protein HER2 plays a role even in breast cancers that would traditionally be categorized as HER2-negative -- and that the drug Herceptin, which targets HER2, may have an even greater role for treating breast cancer and preventing its spread.
NIH/National Cancer Institute, Breast Cancer Research Foundation, Komen for the Cure, University of Michigan/Taubman Institute, Fashion Footwear Charitable Foundation of New York/QVC Presents Shoes-On-Sale, Stand Up to Cancer
Contact: Nicole Fawcett
Public Release: 26-Feb-2013
Journal of UrologyGeorgia physicians' study published in the Journal of Urology This study, '25 Year Disease Free Survival Rate after Irradiation of Prostate Cancer Calculated with the Prostate Specific Antigen Definition of Recurrence Used for Radical Prostatectomy,' is the first-ever to analyze 25 years of follow-up data after radiation therapy treatment for prostate cancer patients. Contact: Logan Moses
Public Release: 26-Feb-2013
Clinical Cancer ResearchU of M researchers identify genetic variation behind acute myeloid leukemia treatment success Researchers from the College of Pharmacy and Medical School working within the Masonic Cancer Center, University of Minnesota, have partnered to identify genetic variations that may help signal which acute myeloid leukemia patients will benefit or not benefit from one of the newest antileukemic agents. Their study is published today in Clinical Cancer Research. Contact: Amy Leslie
Public Release: 26-Feb-2013
Journal of the National Cancer InstituteStudy revises colorectal cancer risk down and other cancer risks up for women with Lynch Syndrome "This new information helps patient care in two important ways. First, it helps us counsel women with Lynch Syndrome who have had endometrial cancer about the magnitude of their future cancer risk. Second, it helps fill in the picture of the spectrum of cancers that are associated with Lynch Syndrome," says co-author. Contact: Garth Sundem
Public Release: 26-Feb-2013
Proceedings of the National Academy of SciencesNovel combination therapy shuts down escape route, killing glioblastoma tumor cells Scientists at Ludwig uncovered an unexpected, but important molecular mechanism of mTOR inhibitor resistance and a novel drug combination that reverses this resistance using low dose arsenic in mice. The mTOR pathway is hyperactivated in 90 percent of glioblastomas, the most lethal brain cancer in adults. The data suggest a new approach for treatment of glioblastoma. Findings were published in this week's Proceedings of the National Academy of Sciences.
National Institutes of Health, Japan Society for the Promotion of Science, and others
Contact: Rachel Steinhardt
Public Release: 25-Feb-2013
Journal of VirologyVirus shows promise as prostate cancer treatment A recombinant Newcastle disease virus kills all kinds of prostate cancer cells, including hormone resistant cells, but leaves normal cells unscathed, according to a paper published online ahead of print in the Journal of Virology. A treatment for prostate cancer based on this virus would avoid the adverse side effects typically associated with hormonal treatment for prostate cancer, as well as those associated with cancer chemotherapies generally. Contact: Jim Sliwa
Public Release: 25-Feb-2013
Journal of Biological ChemistryResearchers at the UH Cancer Center discover protein that may control the spread of cancer Background: RSK2 alters cell migration and metastasis, but the mechanism is incompletely understood. Results: RSK2 inactivates integrins, increases filamin binding to integrin tails, alters actin distribution, increases migration and decreases fibronectin matrix assembly. Conclusion: RSK2 mediates inactivation of integrins and thus modulates integrin functions. Significance: These findings provide a novel mechanism by which RSK2 affects migration and may lead to more selective ways to inhibit RSK2 dependent metastasis.
National Institutes of Health, Robert C. Perry Fund of Hawaii Community Foundation, US Department of Defense
Contact: Lori Strelow
Showing releases 1051-1075 out of 1212. << < 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 > >>
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