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Showing releases 1076-1100 out of 1124.

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Public Release: 12-Jun-2012
Multi-center clinical study intensifies first strike at high-risk cancer in kids
An experimental treatment that combines intense chemotherapy with a radioactive isotope linked to synthesized neurotransmitter is being tested in newly diagnosed cases of high-risk neuroblastoma -- a deadly, hard-to-cure childhood cancer. Doctors in a new multi-center pilot clinical trial want to know if the innovative combination therapy can help improve cure rates for children and young adults.

Contact: Nick Miller
nicholas.miller@cchmc.org
513-803-6035
Cincinnati Children's Hospital Medical Center

Public Release: 12-Jun-2012
Kill the messenger
A small molecule developed at the Weizmann Institute prevents a cancer-causing message from entering the cell nucleus.

Contact: Yivsam Azgad
news@weizmann.ac.il
972-893-43856
Weizmann Institute of Science

Public Release: 12-Jun-2012
Nature Genetics
A study shows that 'mosaicism' is gaining ground in cancer research
A study recently published in Nature Genetics provides new evidence that the genetic makeup of the embryo may cause the appearance of tumors in adult life. These results bear out the growing theory that some tumors may have an extremely early origin, tracing to the individual's embryonic development, while offering new clues to understand the genetic causes of certain kinds of cancer, and their prevention and treatment.

Contact: Juan J. Gomez
juanj.gomez@cnio.es
34-917-328-000
Centro Nacional de Investigaciones Oncologicas (CNIO)

Public Release: 11-Jun-2012
Cancer Cell
Gene inactivation drives spread of melanoma
In a paper published today in the journal Cancer Cell, a team from UNC Lineberger Comprehensive Cancer Center demonstrates that inactivating a gene called LKB1 (or STK11) causes non-aggressive melanoma cells to become highly metastatic when tested in a variety of models using tumors from humans and mice. While Sharpless and his colleagues showed a role for LKB1 inactivation in lung cancer metastasis, the effects of LKB1 loss on melanoma spread is even more dramatic.
NIH/National Cancer Institute, NCI Mouse Model of Human Cancer Consortium, NIH/National Institute on Aging, NIH/National Institute of Environmental Health Sciences

Contact: Ellen de Graffenreid
edegraff@med.unc.edu
919-962-3405
University of North Carolina Health Care

Public Release: 11-Jun-2012
Cancer
Many adolescent and young adult cancer survivors have poor long-term physical and mental health
A new analysis has found that many adolescent and young adult cancer survivors have unhealthy behaviors, chronic medical conditions, a poor quality of life, and significant barriers to health care access. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study indicates that greater efforts are needed to provide quality follow-up care to adolescent and young adult cancer survivors and to encourage them to live more healthily.

Contact: Amy Molnar
healthnews@wiley.com
201-748-8844
Wiley

Public Release: 11-Jun-2012
Journal of Clinical Investigation
Fighting cancer with the immune system
Dr. Jerome Ritz and colleagues at the Dana-Farber Cancer Institute in Boston identify genes that allow cancer cells to escape immune system-mediated death and show data that some of these pathways can be targeted with therapeutics.
National Institutes of Health, International Myeloma Foundation, Multiple Myeloma Research Foundation, Claudia Adams Barr Research Program

Contact: Sarah Jackson
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 11-Jun-2012
2012 Society of Nuclear Medicine Annual Meeting
Molecular imaging signals new treatment protocol for kidney cancer
Research revealed at the Society of Nuclear Medicine's 2012 Annual Meeting explores treatment with a newly developed type of radioimmunotherapy used for treating a resistant form of kidney cancer. The agent is able to hone in on the disease, called clear cell renal carcinoma, and kill the cancer by delivering radiation directly to it. However, the study shows that its effectiveness could be diminished when used after another anti-cancer therapy.

Contact: Susan Martonik
smartonik@snm.org
703-652-6773
Society of Nuclear Medicine

Public Release: 11-Jun-2012
Journal of Clinical Investigation
JCI early table of contents for June 11, 2012
This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, June 11th, 2011, in the JCI: Fighting cancer with the immune system, New mediator of prostate cancer identified, Insights into the mechanisms of acute lung injury, Thyroid hormone stimulates lipid breakdown, and more.

Contact: Sarah Jackson
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 11-Jun-2012
2012 Society of Nuclear Medicine Annual Meeting
New therapy extends life for prostate cancer patients
Prostate cancer patients with advanced tumors that have spread to bone have a poor chance of surviving. Patients with the disease may now live longer with a new line of radioisotope therapy, say researchers at the Society of Nuclear Medicine's 2012 Annual Meeting.

Contact: Susan Martonik
smartonik@snm.org
703-652-6773
Society of Nuclear Medicine

Public Release: 11-Jun-2012
2012 Society of Nuclear Medicine Annual Meeting
State-of-the-art scanning detects more cancer in bone
Research revealed at the Society of Nuclear Medicine's 2012 Annual Meeting describes new approaches to imaging for the detection of tumors in complex cases of bone cancer. Hybrid imaging technology combining computed tomography with molecular imaging agents targeting two different markers of disease came out on top of the list for the detection of bone lesions.

Contact: Susan Martonik
smartonik@snm.org
703-652-6773
Society of Nuclear Medicine

Public Release: 11-Jun-2012
2012 Society of Nuclear Medicine Annual Meeting
PET quickly predicts success of brain cancer treatment
A study revealed at the Society of Nuclear Medicine's 59th Annual Meeting provides some hope for those with a malignant brain cancer called glioma. A method of molecular imaging that mimics an essential amino acid in the brain can now gauge whether the cancer is still active as early as two weeks after the start of treatment without requiring an invasive biopsy.

Contact: Susan Martonik
smartonik@snm.org
703-652-6773
Society of Nuclear Medicine

Public Release: 11-Jun-2012
2012 Society of Nuclear Medicine Annual Meeting
New skin patch treatment kills most common form of skin cancer
A customized patch treatment for basal cell carcinoma completely destroys facial tumors without surgery or major radiation therapy in 80 percent of patients studied, say researchers at the Society of Nuclear Medicine's 2012 Annual Meeting.

Contact: Susan Martonik
smartonik@snm.org
703-652-6773
Society of Nuclear Medicine

Public Release: 11-Jun-2012
Cancer Cell
Studies show that pancreatic cancer can run but not always hide from the immune system
A pair of recent studies describes how pancreatic cancer cells produce a protein that attracts the body's immune cells and tricks them into helping cancer cells grow. The research, published by Cell Press in the June 12 issue of the journal Cancer Cell, also reveals that blocking the protein may be an effective way to treat pancreatic cancer.

Contact: Lisa Lyons
elyons@cell.com
617-386-2121
Cell Press

Public Release: 11-Jun-2012
2012 Society of Nuclear Medicine Annual Meeting
PET predicts outcome of therapy for colorectal cancer patients
A study presented at the Society of Nuclear Medicine's 2012 Annual Meeting reveals how molecular imaging biomarkers can be used to approximate how an experimental radiochemotherapy for locally advanced rectal cancer will work. Using already available imaging probes, scientists can assess the effectiveness before the course of treatment has ended.

Contact: Susan Martonik
smartonik@snm.org
703-652-6773
Society of Nuclear Medicine

Public Release: 11-Jun-2012
2012 Society of Nuclear Medicine Annual Meeting
University of Alberta breakthrough gives hope for new imaging isotope source
A University of Alberta team has made an important breakthrough in the race to find a viable replacement for supply of technetium-99m, an important isotope produced by Canada's Chalk River reactor.

Contact: Jamie Hanlon
jamie.hanlon@ualberta.ca
780-492-9214
University of Alberta

Public Release: 11-Jun-2012
Jounral of the American Chemical Society
New ruthenium-based drugs show promise for killing cancer cells
A new study by University of Kentucky researchers shows how light and strained ruthenium-based drugs may be more effective at fighting cancer cells and less toxic to healthy cells than a similar and widely used drug.

Contact: Allison Perry
allison.perry@uky.edu
859-323-2399
University of Kentucky

Public Release: 11-Jun-2012
Archives of Internal Medicine
Breast cancer risk can be lowered by avoiding unnecessary medical imaging
A report issued by the Institute of Medicine (IOM) last December reviewed all the available scientific data compiled to date about potential environmental risks of breast cancer -- factors such as pesticides, beauty products, household chemicals, and the plastics used to make water bottles

Contact: Jason Socrates Bardi
jason.bardi@ucsf.edu
415-502-4608
University of California - San Francisco

Public Release: 11-Jun-2012
Journal of Cancer Education
Moffitt researchers: African-American couples have unmet needs when affected by prostate cancer
Researchers at Moffitt Cancer Center have found that in African-American families where men are diagnosed with prostate cancer, they have unmet psychosocial needs that affect their survivorship, as well as family and social relationships.

Contact: Patty Kim
patty.kim@moffitt.org
813-745-7322
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 11-Jun-2012
Proceedings of the National Academy of Sciences
Groundbreaking discovery of the cellular origin of cervical cancer
A team of scientists from A*STAR's Institute of Medical Biology, Genome Institute of Singapore together with clinicians from Boston's Brigham and Women's Hospital have identified a unique set of cells in the cervix that are the cause of human papillomavirus-related cervical cancers. Significantly, the team also showed that these cells do not regenerate when excised. These findings have immense clinical implications in the diagnosis, prevention and treatment of cervical cancer.
Agency for Science Technology and Research

Contact: Ong Siok Ming
ong_siok_ming@a-star.edu.sg
65-682-66254
Agency for Science, Technology and Research (A*STAR), Singapore

Public Release: 11-Jun-2012
Nature Medicine
Vanderbilt-led study identifies genes linked to resistance to breast cancer chemotherapy
A study led by Vanderbilt-Ingram Cancer Center (VICC) investigators has identified a gene expression pattern that may explain why chemotherapy prior to surgery isn't effective against some tumors and suggests new therapy options for patients with specific subtypes of breast cancer.
NIH/National Cancer Institute

Contact: Dagny Stuart
Dagny.stuart@vanderbilt.edu
615-936-7245
Vanderbilt University Medical Center

Public Release: 11-Jun-2012
Cancer Cell
Study provides insight into pancreatic cancer progression, new target for treatment
Researchers at NYU School of Medicine have made a key discovery that could help doctors treat one of the deadliest cancers. A new study reveals a strategy used by pancreatic cancer cells to tinker with the immune system in a way that enables them to escape destruction by specialized immune cells.
National Institutes of Health, Pancreatic Cancer Action Network, Irvington Institute Postdoctoral Fellowship Program of the Cancer Research Institute

Contact: Jessica Guenzel
jessica.guenzel@nyumc.org
212-404-3591
NYU Langone Medical Center / New York University School of Medicine

Public Release: 11-Jun-2012
Journal of Consulting and Clinical Psychology
Mindfulness reduces anxiety and depression in cancer patients
An interdisciplinary research project carried out between Aarhus University, Business and Social Sciences and Aarhus University Hospital and the Danish Cancer Society shows that mindfulness-based psychological therapy helps reduce anxiety and depression in cancer patients.
Aarhus University

Contact: Jacob Piet
jacobpj@psy.au.dk
(45) 61-33-45-04
Aarhus University

Public Release: 11-Jun-2012
Proceedings of the National Academy of Sciences
How infection can lead to cancer
One of the biggest risk factors for liver, colon or stomach cancer is chronic inflammation of those organs, often caused by viral or bacterial infections. A new study from MIT offers the most comprehensive look yet at how such infections provoke tissues into becoming cancerous.
NIH/National Cancer Institute

Contact: Caroline McCall
cmccall5@mit.edu
Massachusetts Institute of Technology

Public Release: 11-Jun-2012
Cancer Cell
Normal gene hinders breast cancer chemotherapy
Presence of normal p53, a tumor suppressor gene, instead of a mutated version, makes breast cancer chemotherapy with doxorubicin less effective. The preclinical study led by MD Anderson scientists was published today in the journal Cancer Cell.

Contact: Scott Merville
smerville@mdanderson.org
713-792-0661
University of Texas M. D. Anderson Cancer Center

Public Release: 11-Jun-2012
Proceedings of the National Academy of Sciences
Identifying the origins of cervical cancer
Research from Brigham and Women's Hospital in close collaboration with Harvard Medical School and the Agency for Science Technology and Research in Singapore finds that a specific population of cells that are found only in the region of the cervix called the 'squamo-columnar junction' can become cancerous when infected with HPV while other cells in the cervix apparently do not.
National Institutes of Health, Defense Advanced Research Projects Agency, Singapore-Massachusetts Institute of Technology Alliance for Research and Technology, European Research Council, and others

Contact: Lori J. Schroth
ljshanks@partners.org
617-534-1604
Brigham and Women's Hospital

Showing releases 1076-1100 out of 1124.

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