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Showing releases 1076-1100 out of 1240.

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Public Release: 19-May-2014
Journal of Clinical Oncology
A call to arms in cancer research
The rapid growth in the Hispanic population in the US is not matched by growth in Hispanics participating in cancer clinical trials -- not even close. Given the health disparities experienced by this population it is crucial that cancer researchers include more Hispanics in their trials, and there are steps they can take to do so, in an analysis from the Cancer Therapy & Research Center at the UT Health Science Center San Antonio.
NIH/National Cancer Institute

Contact: Elizabeth Allen
University of Texas Health Science Center at San Antonio

Public Release: 19-May-2014
Annals of Internal Medicine
Study calls for revisiting cardiac screening guidelines for survivors of childhood cancer
One of the first studies to analyze the effectiveness of screening survivors of childhood cancer for early signs of impending congestive heart failure finds improved health outcomes but suggests that less frequent screening than currently recommended may yield similar clinical benefit. The researchers, in a study published in the Annals of Internal Medicine, utilized a simulation-based model to estimate the long-term benefits associated with routine screening.
NIH/National Cancer Institute

Contact: Irene Sege
Dana-Farber Cancer Institute

Public Release: 19-May-2014
Annals of Internal Medicine
Tip sheet from Annals of Internal Medicine May 20, 2014
The May 20 issue of Annals of Internal Medicine includes articles titled: 'Task Force finds insufficient evidence to recommend for or against screening for suicide risk'; 'Vaccination during 'optimal window' is the key to saving lives and money in next flu pandemic'; and 'Two separate studies suggest that longer echocardiographic screening intervals for childhood cancer survivors effective, cost-effective for detecting heart issues.'

Contact: Megan Hanks
American College of Physicians

Public Release: 19-May-2014
Journal of Urology
Low risk prostate cancer not always low risk
Selection of men for active surveillance should be based not on the widely used conventional biopsy, but with a new, image-guided targeted prostate biopsy.
NIH/National Cancer Institute

Contact: Kim Irwin
University of California - Los Angeles Health Sciences

Public Release: 19-May-2014
American Urological Association Annual Meeting
Robot-assisted prostate cancer surgery as safe but more expensive as open surgery in older men
Minimally invasive robot-assisted surgery, which has become the main choice for surgically removing cancerous prostate glands during recent years, is as safe as open surgery for Medicare patients over age 65. Those are the primary findings of a newly published nationwide patient survey that included participation by researchers at Henry Ford Hospital, a pioneer of robot-assisted radical prostatectomy.

Contact: Dwight Angell
Henry Ford Health System

Public Release: 18-May-2014
American Society for Microbiology 114th General Meeting
Bacteria in mouth may diagnose pancreatic cancer
Patients with pancreatic cancer have a different and distinct profile of specific bacteria in their saliva compared to healthy controls and even patients with other cancers or pancreatic diseases, according to research presented today at the annual meeting of the American Society for Microbiology. These findings could form the basis for a test to diagnose the disease in its early stages.

Contact: Jim Sliwa
American Society for Microbiology

Public Release: 18-May-2014
Nano Letters
One small chip -- one giant leap forward for early cancer detection
An international team of researchers, led by ICFO- Institute of Photonic Sciences in Castelldefels, announce the successful development of a 'lab-on-a-chip' platform capable of detecting protein cancer markers in the blood using the very latest advances in plasmonics, nano-fabrication, microfluids and surface chemistry. The device is able to detect very low concentrations of protein cancer markers in blood, enabling diagnoses of the disease in its earliest stages.

Contact: Alina Hirschmann
ICFO-The Institute of Photonic Sciences

Public Release: 16-May-2014
MicroRNA that could be used to suppress prostate cancer progression found
About one in seven men will develop prostate cancer over the course of a lifetime, and about one in 36 men will die from it. This is why findings by Cincinnati Cancer Center researchers, showing that a tumor suppressive microRNA, when activated by an anti-estrogen drug, could contribute to development of future targeted therapies, are important.
Hong Kong University, Chinese University of Hong Kong, NIH/National Cancer Institute, VA, AstraZeneca

Contact: Katie Pence
University of Cincinnati Academic Health Center

Public Release: 16-May-2014
Cancer Epidemiology, Biomarkers & Prevention
Analysis finds wide variation in lung cancer rates globally
The only recent comprehensive analysis of lung cancer rates for women around the world finds lung cancer rates are dropping in young women in many regions of the globe, pointing to the success of tobacco control efforts.
American Cancer Society

Contact: David Sampson
American Cancer Society

Public Release: 16-May-2014
Cancer Epidemiology, Biomarkers & Prevention
Water pipe smoking causes significant exposure to nicotine and cancer-causing agents
Young adults who smoked water pipes in hookah bars had elevated levels of nicotine, cotinine, tobacco-related cancer-causing agents, and volatile organic compounds in their urine, and this may increase their risk for cancer and other chronic diseases, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
National Institutes of Health, California Tobacco-related Disease Research Program

Contact: Jeremy Moore
American Association for Cancer Research

Public Release: 16-May-2014
Journal of the National Cancer Institute
Herpes-loaded stem cells used to kill brain tumors
Harvard Stem Cell Institute scientists at Massachusetts General Hospital have a potential solution for how to more effectively kill tumor cells using cancer-killing viruses. The investigators report that trapping virus-loaded stem cells in a gel and applying them to tumors significantly improved survival in mice with glioblastoma multiform, the most common brain tumor in human adults and also the most difficult to treat.
James S. McDonnell Foundation, National Institutes of Health

Contact: Joseph Caputo
Harvard University

Public Release: 16-May-2014
Journal of Clinical Investigation
JCI online ahead of print table of contents for May 16, 2014
This release contains summaries, links to PDFs, and contact information for the following newsworthy papers published online, May 16, 2014 in the JCI: 'Targeting microbial translocation attenuates SIV-mediated inflammation,' 'Estrogen underlies sex-specific responses to sildenafil,' 'Vaccine-induced cell population inhibits SIV vaccine efficacy,' 'Enhancing efficacy of the cancer drug cetuximab,' 'Beta-catenin-regulated myeloid cell adhesion and migration determine wound healing,' 'Elevated sphingosine-1-phosphate promotes sickling and sickle cell disease progression,' and more.

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 16-May-2014
American Psychosomatic Society Meeting
Cognitive behavioral or relaxation training helps women reduce distress during breast cancer treatment
Can psychological intervention help women adapt to the stresses of breast cancer? It appears that a brief, five-week psychological intervention can have beneficial effects for women who are dealing with the stresses of breast cancer diagnosis and surgery. Intervening during this early period after surgery may reduce women's distress and providing cognitive or relaxation skills for stress management to help them adapt to treatment.

Contact: Annette Gallagher
University of Miami

Public Release: 15-May-2014
Cancer Cell
Genetic tracking identifies cancer stem cells in human patients
The gene mutations driving cancer have been tracked for the first time in patients back to a distinct set of cells at the root of cancer -- cancer stem cells. The international research team, led by scientists at the University of Oxford and the Karolinska Institutet in Sweden, studied a group of patients with myelodysplastic syndromes -- a malignant blood condition which frequently develops into acute myeloid leukemia. The researchers say their findings offer conclusive evidence for the existence of cancer stem cells.
Leukemia and Lymphoma Society, Leukaemia and Lymphoma Research, and others

Contact: University of Oxford
University of Oxford

Public Release: 15-May-2014
New tool to grow cancer cells streamlines laboratory research
A new technique that allows the growth of both normal and cancer cells and keeps them alive indefinitely is transforming and expediting basic cancer research. 'We've had a glimpse of how these cells can provide an amazing advance in human cancer clinical research in preliminary work, and now we demonstrate how incredibly useful they are in laboratory cancer research,' says the lead researcher.
National Institutes of Health

Contact: Karen Teber
Georgetown University Medical Center

Public Release: 15-May-2014
Cell Reports
First test of pluripotent stem cell therapy in monkeys is a success
Researchers have shown for the first time in an animal that is more closely related to humans that it is possible to make new bone from stem-cell-like induced pluripotent stem cells (iPSCs) made from an individual animal's own skin cells. The study in monkeys also shows that there is some risk that those iPSCs could seed tumors, but that unfortunate outcome appears to be less likely than studies in immune-compromised mice would suggest.

Contact: Mary Beth O'Leary
Cell Press

Public Release: 15-May-2014
Journal of Pain and Symptom Management
Next frontier: How can modern medicine help dying patients achieve a 'good' death?
The overall quality of death of cancer patients who die in an urban Canadian setting with ready access to palliative care was found to be good to excellent in the large majority of cases, helping to dispel the myth that marked suffering at the end of life is inevitable.

Contact: Alex Radkewycz
University Health Network

Public Release: 15-May-2014
Journal of the National Cancer Institute
Tumor cells in the blood may indicate poor prognosis in early breast cancer
Tumor cells in bone marrow of early breast cancer patients predict a higher risk of relapse as well as poorer survival, but bone marrow biopsy is an invasive and painful procedure. Now, it may be possible to identify tumor cells in a routine blood sample and use them as prognostic markers, according to a study published May 15 in the Journal of the National Cancer Institute.

Contact: Zachary Rathner
Oxford University Press USA

Public Release: 15-May-2014
Proceedings of the National Academy of Sciences
Learning from sharks
Genetically engineered antibodies are deployed successfully in cancer diagnostics and therapy. Therapeutic antibodies against Alzheimer's disease and multiple sclerosis are currently under development. An important criterion when designing suitable antibody fragments is their stability. Comparing the antibodies of sharks with those of humans, a team of researchers at the Technische Universitaet Muenchen and the Helmholtz Zentrum Muenchen discovered stabilizing mechanisms that can also be applied to optimize custom-tailored antibodies for medical applications.
German Research Foundation, European Molecular Biology Organization, Swedish Research Council, National Institute of Health, German National Academic Foundation

Contact: Dr. Andreas Battenberg
Technische Universitaet Muenchen

Public Release: 15-May-2014
Nature Photonics
Going beyond the surface
The new tech involves using near-infrared beams of light that, upon penetrating deep into the body, are converted into visible light that activates the drug and destroys the tumor.
Air Force of Scientific Research

Contact: Cory Nealon
University at Buffalo

Public Release: 15-May-2014
ASCO 50th Annual Meeting
Getting chemo first may help in rectal cancer
A new phase II study to be presented at the annual meeting of the American Society for Clinical Oncology finds that if chemotherapy is offered before radiation and surgery, more patients will be able to tolerate it and receive a full regimen of treatment.
Brown University

Contact: David Orenstein
Brown University

Public Release: 15-May-2014
Nature Structural & Molecular Biology
Detailed studies reveal how key cancer-fighting protein is held in check
St. Jude Children's Research Hospital scientists have mapped the structural details of how p53 attaches to its regulatory protein, called BCL-xL, in the cell. The protein p53 is a key activator of the cell's protective machinery against genetic damage, such as the mutations that drive cancer cells' explosive growth.
National Institutes of Health, NIH/National Cancer Institute, American-Lebanese-Syrian Associated Charities

Contact: Summer Freeman
St. Jude Children's Research Hospital

Public Release: 15-May-2014
Anticancer Research
Cancer's potential on-off switch
A team of Boston University School of Medicine researchers have proposed that an 'on and off' epigenetic switch could be a common mechanism behind the development of different types of cancer. Epigenetics is the phenomena whereby genetically identical cells express their genes differently, resulting in different physical traits. Researchers from the Boston University Cancer Center recently published two articles about this in Anticancer Research and Epigenomics.

Contact: Jenny Eriksen Leary
Boston University Medical Center

Public Release: 14-May-2014
Journal of Visualized Experiments
SapC-DOPS technology may help with imaging brain tumors, research shows
The Cincinnati Cancer Center and University of Cincinnati Cancer Institute research studies published in an April online issue of the Journal of Magnetic Resonance Imaging and a May issue of the Journal of Visualized Experiments reveal possibly new ways to image glioblastoma multiforme tumors -- a form of brain tumor -- using the SapC-DOPS technology.
Mayfield Education and Research Foundation, New Drug State Key Project, NIH/National Cancer Institute

Contact: Katie Pence
University of Cincinnati Academic Health Center

Public Release: 14-May-2014
Journal of the National Cancer Institute
Study shows breastfeeding, birth control may reduce ovarian cancer risk in women with BRCA mutations
Breastfeeding, tubal ligation -- also known as having one's 'tubes tied' -- and oral contraceptives may lower the risk of ovarian cancer for some women with BRCA gene mutations, according to a comprehensive analysis from a team at the University of Pennsylvania's Basser Research Center for BRCA and the Abramson Cancer Center. The findings, a meta-analysis of 44 existing peer-reviewed studies, are published in the Journal of the National Cancer Institute.

Contact: Katie Delach
University of Pennsylvania School of Medicine

Showing releases 1076-1100 out of 1240.

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