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Showing releases 1076-1100 out of 1311.

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Public Release: 3-Dec-2015
Nature Communications
How to wake a sleeping cancer cell -- and why you might want to
Cancer cells that lie 'snoozing' in the skeleton can be awakened by changes in the bone that surrounds them, Australian scientists have shown. In a world first, researchers from the Garvan Institute of Medical Research have used state-of-the-art microscopy techniques to watch cancer cells sleep within living bone over a period of months. They show that cancer cells can be 'woken up' when bone tissue is broken down around them, suggesting new possibilities for treating metastatic cancer in bone.
Mrs. Janice Gibson, Ernest Heine Family Foundation, National Health and Medical Research Council (Australia), International Bone and Mineral Society, Australian Research Council, Leukaemia and Lymphoma Research

Contact: Meredith Ross
Garvan Institute of Medical Research

Public Release: 3-Dec-2015
Cell Reports
Spreading cancer cells must change their environment to grow
Spreading cancer cells arriving in a new part of the body must be able to change their new environment to continue to grow.

Contact: Press Office
Cancer Research UK

Public Release: 3-Dec-2015
Annals of Oncology
Study shows abiraterone acetate is useful even in most aggressive prostate cancers
In study of nearly 2,000 prostate cancer patients, treatment with the androgen-lowering drug abiraterone acetate (Zytiga) led to longer overall disease control, even when a very high Gleason score indicated especially aggressive cancer.

Contact: Garth Sundem
University of Colorado Anschutz Medical Campus

Public Release: 3-Dec-2015
'Master switch' helps cancer cells survive stress
Scientists have discovered a 'master switch' within cancer cells that seems to override the normal stress response and allows them to survive conditions that would normally be lethal. The mechanism could be critical in allowing cancer cells to withstand the huge amounts of stress they come under as they divide rapidly and their metabolism goes into overdrive.
The Institute of Cancer Research, Biotechnology and Biological Sciences Research Council

Contact: Claire Hastings
Institute of Cancer Research

Public Release: 3-Dec-2015
JAMA Oncology
Neurotoxic effects of chemotherapies on cognition in breast cancer survivors
Cancer-related cognitive impairment is often referred to as 'chemobrain' and anthracycline-based chemotherapy may have greater negative effects on particular cognitive domains and brain network connections than nonanthracycline-based regimens, according to an article published online by JAMA Oncology.

Contact: Laura Sussman
The JAMA Network Journals

Public Release: 3-Dec-2015
Scientific Reports
Researchers isolate cells implicated with breast cancer-derived brain tumors
Researchers from the Houston Methodist Research Institute have isolated genetic signatures of some circulating tumor cells found in breast cancer, which one day may lead to a preventive treatment for metastatic cancer cells.

Contact: Gale Smith
Houston Methodist

Public Release: 3-Dec-2015
Advanced Materials
'Nanobombs' might deliver agents that alter gene activity in cancer stem cells
Researchers at The Ohio State University Comprehensive Cancer Center -- Arthur G. James Cancer Hospital and Richard J. Solove Research Institute have developed nanoparticles that swell and burst when exposed to near-infrared laser light. Such 'nanobombs' might overcome a biological barrier that has blocked development of agents that work by altering the activity -- the expression -- of genes in cancer cells. The agents might kill cancer cells outright or stall their growth.
American Cancer Society, Pelotonia Postdoctoral Fellowship

Contact: Darrell E. Ward
Ohio State University Wexner Medical Center

Public Release: 3-Dec-2015
57th ASH Annual Meeting & Exposition
Cancer Cell
Targeting protein homeostasis holds potential to treat solid tumors and blood cancers
In data published in two journals as well as to be presented at the American Society of Hematology Annual Meeting & Exposition, scientists identified an orally available molecule, CB-5083, that targeting protein homeostasis has the potential to treat solid tumors and blood cancers.
Cleave Biosciences

Contact: Pam Lord
Canale Communications

Public Release: 3-Dec-2015
Scientific Reports
Researchers use ovarian follicles to preserve fertility
Researchers at the University of Michigan have identified a potential new approach to fertility preservation for young cancer patients that addresses concerns about beginning cancer treatment immediately and the possibility of reintroducing cancer cells during the fertility preservation process.
National Institutes of Health

Contact: Nicole Fawcett
University of Michigan Health System

Public Release: 2-Dec-2015
Cancer Epidemiology, Biomarkers & Prevention
False-positive mammograms may indicate increased risk of breast cancer later
Women with a history of a false-positive mammogram result may be at increased risk of developing breast cancer for up to 10 years after the false-positive result.
Breast Cancer Surveillance Consortium, National Institutes of Health

Contact: Lauren Riley
American Association for Cancer Research

Public Release: 2-Dec-2015
Researchers unravel age-old mystery of why cells use fermentation
Wine, beer and yogurt are produced when microorganisms convert sugar into alcohol, gases or acids. But this process of fermentation -- which is used by bacteria, fungi and other fast-growing cells to generate energy in the absence of oxygen -- is a much less efficient way of generating energy for cells than aerobic respiration. So why do many organisms use this seemingly wasteful strategy to generate energy instead of aerobic respiration, even when oxygen is readily available?
National Institutes of Health, Simons Foundation, Walter Haefner Foundation, ETH Foundation

Contact: Kim McDonald
University of California - San Diego

Public Release: 2-Dec-2015
Proceedings of the National Academy of Sciences
Studying stonefish venom may help combat transplant rejection
Monash University researchers have solved the X-ray crystal structure of the lethal factor present in stonefish venom. The discovery has provided unexpected insight into a crucial human immune response that is responsible for the failure of up to 30 percent of bone marrow transplant therapies for treating leukemia.

Contact: Alexia Lyons
Monash University

Public Release: 2-Dec-2015
RNA mystery solved in triple negative breast cancer
Researchers at Thomas Jefferson University have discovered why conventional efforts to block a tiny strand of ribonucleic acid, called microRNA, in triple negative breast cancer cells failed.

Contact: Colleen A Cordaro
Thomas Jefferson University

Public Release: 2-Dec-2015
Journal of Pathology
Researchers develop antibody to save cancerous bones
Osteosarcoma is a rare cancer most often affecting adolescents and children. While most bone cancers have their origin in other body tissues and spread to the bones through metastases, OS originates in the bone tissue. At the Finsen Laboratory, University of Copenhagen researchers now shows that OS cells degrade the bone tissue through a completely different process than metastasized bone cancer. Through treatment with a specific antibody, the researchers blocked the process and reduced up to 80 percent of bone degradation in a cancer model.
Danish Medical Research Council, Danish Cancer Society, Novo Nordisk Foundation, Lundbeck Foundation, Danish National Research Foundation under the programme Danish-Chinese Centre for Proteases and Cancer

Contact: Niels Behrendt
University of Copenhagen, Biotech Research & Innovation Centre

Public Release: 2-Dec-2015
RSNA 2015 101st Scientific Assembly and Annual Meeting
Study suggests breast density alone not a risk factor for cancer
Breast density may not be a strong independent factor for breast cancer risk, according to a new study.

Contact: Linda Brooks
Radiological Society of North America

Public Release: 2-Dec-2015
Nature Communications
Liquid metal 'nano-terminators' target cancer cells
Researchers have developed a new drug delivery technique that uses a biodegradable liquid metal to target cancer cells. The liquid metal drug delivery method promises to boost the effect of cancer drugs.
National Institutes of Health, National Science Foundation

Contact: Matt Shipman
North Carolina State University

Public Release: 2-Dec-2015
New studies create better understanding of cancer-spreading enzymes
Researchers at the University of Missouri have determined a detailed structural view of one of these enzymes, called MMP7, as it binds to the membranes, or surfaces, of cancer cells. This understanding could lead to better treatments for cancer.
National Institutes of Health, Burroughs Wellcome Fund Career Award at the Scientific Interface

Contact: Nathan Hurst
University of Missouri-Columbia

Public Release: 2-Dec-2015
57th ASH Annual Meeting & Exposition
Sylvester presents latest cancer research at ASH Annual Meeting
Researchers from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine will present a selection of the latest advances in hematology research at this year's American Society of Hematology Annual Meeting, Dec. 5-8, at the Orange County Convention Center in Orlando, Fla.

Contact: Patrick Bartosch
University of Miami Miller School of Medicine

Public Release: 2-Dec-2015
Crop Science
Fries with a side of acrylamide
French fry lovers, beware! You may be exposed to a chemical more commonly associated with heavy industry than crispy fried potatoes. Fortunately, researchers are finding ways to reduce that exposure.
US Potato Board, Cavendish Foods, ConAgra Lamb-Weston, J.R. Simplot, McCain Foods, National Institute of Food and Agriculture USDA Specialty Crop Research Initiative

Contact: Susan Fisk
American Society of Agronomy

Public Release: 2-Dec-2015
57th ASH Annual Meeting & Exposition
City of Hope researchers present study results at American Society of Hematology meeting
Clinical trials that lay the groundwork for novel leukemia and lymphoma treatments will be among the highlights of the annual meeting of the American Society of Hematology (ASH) getting under way this week in Orlando. The trials, presented by researchers and physicians from City of Hope, could ultimately lead to innovative therapeutic approaches that improve survival and quality of life for patients with those and other diseases.

Contact: Letisia Marquez
City of Hope

Public Release: 2-Dec-2015
Scientific Reports
Scientists design a new method for screening cancer cells
UCLA life scientists and colleagues today present a new method they developed to screen cancer cells and identify small molecules that can make cancer cells less lethal.

Contact: Stuart Wolpert
University of California - Los Angeles

Public Release: 2-Dec-2015
European Radiology
Breast density alone found not to be a factor for breast cancer risk
Although several studies suggest that women with denser breast tissue have an increased risk of breast cancer, a new study by Johns Hopkins researchers discredits breast density as a risk factor in and of itself.
NIH/National Cancer Institute

Contact: Marin Hedin
Johns Hopkins Medicine

Public Release: 2-Dec-2015
The Journal of Alternative and Complementary Medicine
New study shows high use of complementary therapies by cancer inpatients
Patients hospitalized for cancer treatment commonly use complementary and integrative health (CIH) approaches such as nutritional supplements, special diets, and massage according to a new study. More than 95 percent of patients expressed interest in at least one of these types of therapies if offered during their hospital stay, as reported in the article published in The Journal of Alternative and Complementary Medicine.

Contact: Kathryn Ryan
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 2-Dec-2015
Laboratory Investigation
Genetic mutations differ within a single tumor, study finds
When researchers looked at different areas within an individual rectal cancer sample, they found cases in which each area contained different genetic mutations. The findings could have significant implications for treatment recommendations.
NIH/National Cancer Institute, American Surgical Association Foundation Fellowship

Contact: Nicole Fawcett
University of Michigan Health System

Public Release: 1-Dec-2015
How does your garden grow? For cancer patients, small gardens could bring big benefits
Nature is full of benefits for the cancer patients, but it isn't always accessible. In the latest article in ecancermedicalscience, a team of researchers led by Dr Ceri Phelps of the University of Wales Trinity Saint David, Swansea, Wales decided to test a simpler, smaller approach -- accessible, cheap, and not prone to whims of weather.

Contact: Audrey Nailor

Showing releases 1076-1100 out of 1311.

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