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Showing releases 1076-1100 out of 1299.

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Public Release: 23-Jun-2015
Viagra does something very important -- but it is unlikely to cause melanoma, researchers conclude
A rigorous analysis of more than 20,000 medical records concludes that erectile dysfunction drugs, such as Viagra, are not a cause of melanoma, an often deadly form of skin cancer, despite the higher risk for the disease among users of these drugs.

Contact: David March
NYU Langone Medical Center / New York University School of Medicine

Public Release: 23-Jun-2015
Annals of Surgery
Researchers develop new breath test to diagnose esophageal and gastric cancer
Researchers have devised a breath test that can help doctors diagnose the early signs of esophageal and gastric cancer in minutes.
NIHR Imperial Biomedical Research Centre, NIHR-diagnostic Evidence Cooperatives

Contact: Maxine Myers
Imperial College London

Public Release: 23-Jun-2015
CT allows nonsurgical management of some lung nodules
People who have nonsolid lung nodules can be safely monitored with annual low-dose computed tomography screening, according to a new study. Researchers said the findings could help spare patients from unnecessary surgery and additional imaging.
National Institutes of Health

Contact: Linda Brooks
Radiological Society of North America

Public Release: 23-Jun-2015
Journal of Adolescent Health
Adolescents uncertain about risks of marijuana, e-cigarettes, Stanford study finds
Teenagers are very familiar with the risks of smoking cigarettes, but are much less sure whether marijuana or e-cigarettes are harmful, according to a new study by researchers at the Stanford University School of Medicine.
NIH/National Cancer Institute

Contact: Erin Digitale
Stanford University Medical Center

Public Release: 23-Jun-2015
The American Journal of Surgical Pathology
'Smarter' ordering of breast biomarker tests could save millions in health care dollars
A review of medical records for almost 200 patients with breast cancer suggests that more selective use of biomarker testing for such patients has the potential to save millions of dollars in health care spending without compromising care, according to Johns Hopkins researchers.

Contact: Shawna Williams
Johns Hopkins Medicine

Public Release: 23-Jun-2015
Current blood cancer drug prices not justified, MD Anderson study finds
The costs associated with cancer drug prices have risen dramatically over the past 15 years, which is of concern to many top oncologists. In a new analysis, researchers at The University of Texas MD Anderson Cancer Center concluded the majority of existing treatments for hematologic, or blood, cancers are currently priced too high to be considered cost-effective in the United States.

Contact: Clayton R. Boldt
University of Texas M. D. Anderson Cancer Center

Public Release: 23-Jun-2015
Genome Medicine
New colon cancer culprit found in gut microbiome
Changes in the gut bacteria of colon cancer patients indicate that some virulent bacteria could be linked to the progression of the disease, according to research published in the open-access journal Genome Medicine. The findings could eventually be used to identify a virulence signature in these cancers and help doctors predict how bacterial changes in patients' guts could affect their prognosis.

Contact: Alanna Orpen
BioMed Central

Public Release: 22-Jun-2015
Study finds decreased rates of high-grade cervical lesions in young women
A new analysis indicates that rates of high-grade cervical lesions decreased in young US women after vaccines were made available to protect against human papillomavirus (HPV), but the trend may be due in part to changes in cervical cancer screening recommendations.

Contact: Evelyn Martinez

Public Release: 22-Jun-2015
Journal of the National Cancer Institute
Higher sTNF-RII associated with reduced memory functioning among breast cancer patients before treatment
Pretreatment cytokine levels, specifically soluble TNF receptor type two (sTNF-RII), are associated with reduced memory performance among newly-diagnosed, post-menopausal breast cancer (BC) patients prior to receipt of surgery and/or adjuvant therapy, according to a new study published June 22 in the JNCI: Journal of the National Cancer Institute.

Contact: Zachary Rathner
Oxford University Press USA

Public Release: 22-Jun-2015
Journal of the American College of Cardiology
Cardio-oncology services may improve patient care if more widely available
The impact of cancer treatments on cardiovascular health is an important consideration when treating cancer patients, but many hospital training programs have no formal training or services in cardio-oncology and a lack of national guidelines and funding are frequent barriers to establishing such programs, according to a nationwide survey published today in the Journal of the American College of Cardiology.

Contact: Nicole Napoli
American College of Cardiology

Public Release: 22-Jun-2015
Canadian Medical Association Journal
Most women with early-stage breast cancer undergo imaging for metastatic cancer despite guidelines
Most women -- about 86 percent -- with early-stage breast cancer will undergo imaging to determine if the cancer has metastasized, despite international guidelines that recommend against testing, found a study in CMAJ (Canadian Medical Association Journal).
Patient Quality and Safety Committee, Department of Medicine and Division of Medical Oncology, University of Ottawa

Contact: Kim Barnhardt
613-520-7116 x2224
Canadian Medical Association Journal

Public Release: 22-Jun-2015
A fuse of cardiovascular diseases
A promising biomarker for the severity of age-related white matter changes and endothelial function was evaluated at Hiroshima University, Japan. The researchers at Hiroshima University investigated the association between the telomeric 3'-overhang length of leukocytes and vascular risk, ARWMCs, and endothelial function. They suggested that the telomere G-tail might be a useful marker of endothelial dysfunction, as well as stroke and dementia.
Smoking Research Foundation, Tsuchiya Foundation, Japan Science and Technology Agency, Japan Heart Foundation, Scientific Research on Priority Areas from the Ministry of Education

Contact: Norifumi Miyokawa
Hiroshima University

Public Release: 22-Jun-2015
Stress hormones could undermine breast cancer therapy
Stress hormones often given to patients to treat the side effects of therapy may cause a subset of breast cancers to become treatment-resistant.

Contact: Edyta Zielinska
Thomas Jefferson University

Public Release: 22-Jun-2015
Journal of Nuclear Medicine
Award-winning agent developed for prostate cancer diagnosis and treatment
Scientists at the German Cancer Research Center have developed an agent called PSMA-617, which is capable of attaching specifically to prostate cancer cells. This agent can be labeled with various radioactive substances. When chemically bound to a weakly radioactive diagnostic radionuclide, it can detect prostate tumors and their metastases in PET scans. If labeled with a strongly radioactive therapeutic radionuclide, PSMA-617 can specifically destroy cancer cells. A first clinical application of this radiopharmaceutical at Heidelberg University Hospital has now delivered promising results.

Contact: Stefanie Seltmann
German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)

Public Release: 22-Jun-2015
International Society of Thrombosis and Hemostasis Meeting
New England Journal of Medicine
Study could reduce unnecessary cancer screening
A large clinical trial led by researchers at The Ottawa Hospital and the University of Ottawa has found that contrary to expectations, a CT scan of the abdomen and pelvis does not improve cancer detection in people with unexplained blood clots in their legs and lungs. The results, published in the June 22nd edition of the New England Journal of Medicine, are expected to improve patient care and reduce screening costs around the world.
Heart and Stroke Foundation of Canada, Ottawa Hospital Foundation

Contact: Lois Ross
613-737-8899 x73687
Ottawa Hospital Research Institute

Public Release: 19-Jun-2015
Cell Reports
Supercomputers surprisingly link DNA crosses to cancer
Supercomputers have helped scientists find a surprising link between cross-shaped (or cruciform) pieces of DNA and human cancer, according to a study at The University of Texas at Austin (UT Austin).
National Science Foundation

Contact: Faith Singer-Villalobos
University of Texas at Austin, Texas Advanced Computing Center

Public Release: 19-Jun-2015
Discovery promises new treatments to thwart colon cancer
Scientists at St. Jude Children's Research Hospital have discovered how an immune system protein, called AIM2 (Absent in Melanoma 2), plays a role in determining the aggressiveness of colon cancer. They found that AIM2 deficiency causes uncontrolled proliferation of intestinal cells. Surprisingly, they also discovered that AIM2 influences the microbiota -- the population of gut bacteria -- apparently fostering the proliferation of 'good' bacteria that can protect against colon cancer.
National Institutes of Health, ALSAC

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Public Release: 19-Jun-2015
Journal of Cancer Education
Latina women undergoing chemotherapy for breast cancer need more stress management tools
Moffitt Cancer Center researchers, along with collaborators at the University of South Florida, recently published a study about the attitudes and cultural perspectives of Latinas undergoing chemotherapy for breast cancer. The article also discusses their cancer experiences and the ways they manage stress associated with cancer.
Komen for the Cure

Contact: Kimberly Polacek
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 19-Jun-2015
Moffitt researchers discover mechanism leading to BRAF inhibitor resistance in melanoma
The development of targeted therapies has significantly improved the survival of melanoma patients over the last decade; however, patients often relapse because many therapies do not kill all of the tumor cells, and the remaining cells adapt to treatment and become resistant. Moffitt Cancer Center researchers have discovered a novel mechanism that can lead melanoma cells to develop resistance to drugs that target the protein BRAF.
National Insitutes of Health

Contact: Kim Polacek
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 18-Jun-2015
Future Oncology
Future oncology explores role of biomarkers and next generation sequencing
Highlighting the seismic shift in cancer research and treatment that is underway due to biomarkers and next generation sequencing, a special issue of Future Oncology offers multiple review articles summarizing the opportunities presented by improvements in molecular testing and analysis.

Contact: Leela Ripton
Future Science Group

Public Release: 18-Jun-2015
Cell Stem Cell
Scientists identify progenitor cells for blood and immune system
University of California San Francisco scientists have identified characteristics of a family of daughter cells, called MPPs, which are the first to arise from stem cells within bone marrow that generate the entire blood system
National Institutes of Health, Leukemia and Lymphoma Society, Wellcome Trust

Contact: Laura Kurtzman
University of California - San Francisco

Public Release: 18-Jun-2015
Nature Genetics
Detroit researchers help identify gene mutation that can trigger lymphoblastic leukemia
After collecting data on a leukemia-affected family for nearly a decade, Children's Hospital of Michigan Hematologist and Wayne State University School of Medicine Professor of Pediatrics Madhvi Rajpurkar, M.D., joined an international team of genetic researchers in an effort to track down a mutation partly responsible for causing the disease. Their findings, recently published in one of the world's leading science journals, have 'major implications' for better understanding the genetic basis of several types of cancer, including leukemia.
National Institutes of Health, Postle Family Chair in Pediatric Cancer and Blood Disorders

Contact: Julie O'Connor
Wayne State University - Office of the Vice President for Research

Public Release: 18-Jun-2015
Biomedical breakthrough: Carbon nanoparticles you can make at home
Researchers have found an easy way to produce carbon nanoparticles that are small enough to evade the body's immune system, reflect light in the near-infrared range for easy detection, and carry payloads of pharmaceutical drugs to targeted tissues. The new approach generates the particles in a few hours and uses only a handful of ingredients, including store-bought molasses.

Contact: Diana Yates
University of Illinois at Urbana-Champaign

Public Release: 18-Jun-2015
Analytical and Bioanalytical Chemistry
New tool on horizon for surgeons treating cancer patients
Surgeons could know while their patients are still on the operating table if a tissue is cancerous, according to researchers from the Department of Energy's Oak Ridge National Laboratory and Brigham and Women's Hospital/Harvard Medical School.

Contact: Ron Walli
DOE/Oak Ridge National Laboratory

Public Release: 18-Jun-2015
Massively parallel gene function assays aim to reduce uncertainty of genetic diagnoses
Patients seeking certainty in genetic tests often receive a perplexing result. Many learn they carry a 'variant of unknown significance' of a disease-linked gene. Such variants might -- or equally might not -- increase disease risk. A study published in the June issue of the journal Genetics characterized nearly 2000 variants of the breast cancer-associated gene BRCA1, demonstrating the potential of a new approach for sorting out which variants are harmful and which are harmless.

Contact: Tracey DePellegrin
Genetics Society of America

Showing releases 1076-1100 out of 1299.

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