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Showing releases 1076-1100 out of 1330.

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Public Release: 8-Jan-2015
AMP releases 'A Molecular Diagnostic Perfect Storm' paper
Health care providers -- those developing and delivering innovative diagnostic tests -- along with patients, who are the ultimate intended beneficiaries, are caught in the middle of policies imposed by FDA and CMS.

Contact: Catherine Davidge
cdavidge@amp.org
301-634-7400
Association for Molecular Pathology

Public Release: 8-Jan-2015
Journal of the Academy of Nutrition and Dietetics
Nutrition intervention leads to dietary behavior changes in Latina breast cancer survivors
An intervention designed to provide Latina breast cancer survivors with the knowledge and skills needed to change and sustain dietary behaviors helps survivors adhere to recommended guidelines to eat a diet high in fruits and vegetables. Using a culturally based hands-on educational approach, the program is geared toward Latina breast cancer survivors whose are at higher risk of high obesity rates, low physical activity rates, and poorer access to quality healthcare.
NIH/National Cancer Institute

Contact: Stephanie Berger
sb2247@columbia.edu
212-305-4372
Columbia University's Mailman School of Public Health

Public Release: 8-Jan-2015
Prostate
New study findings help physicians and patients determine prostate cancer risk
A discovery by researchers at Huntsman Cancer Institute shows that looking at whether a man's uncles and great-grandparents, among other second- and third-degree relatives, had prostate cancer could be as important as looking at whether his father had prostate cancer. A more complete family history would give physicians a new tool to decide whether or not a prostate-specific antigen test was appropriate.
US Department of Defense, NIH/National Cancer Institute, Huntsman Cancer Foundation

Contact: Linda Aagard
801-587-7639
University of Utah Health Sciences

Public Release: 8-Jan-2015
Science
Scientists illuminate mysterious molecular mechanism powering cells in most forms of life
A team led by structural biologists at The Scripps Research Institute has taken a big step toward understanding the intricate molecular mechanism of a metabolic enzyme produced in most forms of life on Earth. The finding concerns nicotinamide nucleotide transhydrogenase, an ancient evolutionary enzyme that is part of a process key to maintaining healthy cells and has also recently been linked to diseases such as diabetes and cancer.
National Institutes of Health, NIH/National Institute of General Medical Sciences

Contact: Madeline McCurry-Schmidt
madms@scripps.edu
858-784-9254
Scripps Research Institute

Public Release: 8-Jan-2015
Cancer Cell
Blood vessel lining cells control metastasis
Scientists from the German Cancer Research Center in Heidelberg and from the Medical Faculty Mannheim of Heidelberg University paved the way for an innovative combination therapy against metastases: They treated mice with a combination of a low-dose metronomic chemotherapy and an antibody against Ang-2, a regulatory protein of the blood vessel lining cells. The treated animals had significantly less metastases.

Contact: Dr. Sibylle Kohlstädt
s.kohlstaedt@dkfz.de
German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)

Public Release: 8-Jan-2015
Lancet Respiratory Medicine
How quickly smokers metabolize nicotine may point to most effective way to quit
In a first-of-its-kind randomized clinical trial, researchers from Penn Medicine and collaborators have shown that the most-suited treatment for each smoker may depend on how quickly they metabolize the nicotine in their body after quitting.
NIH/National Institute on Drug Abuse, NIH/National Cancer Institute, NIH/National Institute of General Medical Sciences, NIH/National Human Genome Research Institute

Contact: Steve Graff
stephen.graff@uphs.upenn.edu
215-349-5653
University of Pennsylvania School of Medicine

Public Release: 8-Jan-2015
Gynecologic Oncology
Screening HPV infection alone more accurate than Pap test in detection of cervical cancer
Screening for human papillomavirus (HPV) infection alone gives more accurate results than Pap testing for cervical cancer, say the authors of two papers to published today in the journal Gynecologic Oncology.

Contact: Sarah Jenkins
sl.jenkins@elsevier.com
44-186-584-3243
Elsevier

Public Release: 7-Jan-2015
Research advocates urge Congress to advance top 5 science priorities in first 100 days
Research!America urges the 114th Congress to take action on five science priorities in the first 100 days of the legislative session in order to elevate research and innovation on the nation's agenda. The five priorities: End sequestration, increase funding for our nation's research agencies, advance the 21st Century Cures initiative, repeal the medical device tax, and enact a permanent and enhanced R&D tax credit.

Contact: Anna Briseno
abriseno@researchamerica.org
571-482-2737
Research!America

Public Release: 7-Jan-2015
Radiotherapy & Oncology
Potential new tool to monitor radiotherapy side effects
Researchers in Manchester have investigated a patient-centered approach to assessing the side effects of radiotherapy and have shown that it may be able to improve the detection and management of treatment-related toxicity.
European Union Seventh Framework Programme

Contact: Jamie Brown
Jamie.brown@manchester.ac.uk
44-016-127-58383
University of Manchester

Public Release: 7-Jan-2015
ecancermedicalscience
Are we there yet? A new tool to measure progress in cancer research
In a new paper published today in ecancermedicalscience, researchers aim to measure progress in cancer research through the use of a new tool that relies on multiple measures to determine the 'progress' and 'value' of research.

Contact: Katie Foxall
katie@ecancer.org
44-117-942-0852
ecancermedicalscience

Public Release: 7-Jan-2015
New England Journal of Medicine
Combined therapy can reduce chance of recurrence in women with small, HER2+ breast tumors
Dana-Farber researchers report women with small, HER2-positive breast tumors who received a combination of lower-intensity chemotherapy and a targeted drug following surgery were highly unlikely to have the cancer recur within three years.
Genentech, Susan G. Komen for the Cure

Contact: John Noble
johnw_noble@dfci.harvard.edu
617-632-4090
Dana-Farber Cancer Institute

Public Release: 7-Jan-2015
Journal of the American Chemical Society
Selective functionalization synthesizes chemotherapeutic natural products
Through an extensive international collaboration, scientists at the Center for Selective C-H Functionalization, Emory University and the Institute of Transformative Bio-Molecules, Nagoya University have synthesized marine alkaloids with anti-cancer and therapeutic properties through a sequential C-H functionalization strategy.

Contact: Dr. Ayako Miyazaki
press@itbm.nagoya-u.ac.jp
81-527-894-999
Institute of Transformative Bio-Molecules (ITbM), Nagoya University

Public Release: 7-Jan-2015
American Journal of Preventive Medicine
Analysis finds federal government under-funds chronic disease prevention research
The first comprehensive analysis of National Institutes of Health funding of research to prevent non-communicable chronic diseases shows that prevention research in the United States is severely underfunded. The study published today in the American Journal of Preventive Medicine.
The Vitality Institute, National Institutes of Health

Contact: Tom Langford
tom.langford@fkhealth.com
617-761-6775
The Vitality Institute

Public Release: 7-Jan-2015
Sticking to lifestyle guidelines may reduce risk for certain cancers and for overall mortality
A study of nearly a half-million Americans has found that following cancer prevention guidelines from the American Cancer Society may modestly reduce your overall risk of developing cancer and have a greater impact on reducing your overall risk of dying. Having a healthy body weight and staying active appeared to have the most positive impact.

Contact: Deirdre Branley
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine

Public Release: 7-Jan-2015
Science Translational Medicine
Surprise: High-dose testosterone therapy helps some men with advanced prostate cancer
In a surprising paradox, the male hormone testosterone, generally thought to be a feeder of prostate cancer, has been found to suppress some advanced prostate cancers and also may reverse resistance to testosterone-blocking drugs used to treat prostate cancer.
One-in-Six Foundation

Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medicine

Public Release: 7-Jan-2015
Practical Radiation Oncology
Physician survey indicates positive experience, desire for formal guidelines to improve peer review
A 2013 survey of radiation oncologists indicates that they would like more formal recommendations and guidance in order to improve the peer review process, according to a study published in the January-February 2015 issue of Practical Radiation Oncology, the clinical practice journal of the American Society for Radiation Oncology.

Contact: Michelle Kirkwood
press@astro.org
703-286-1600
American Society for Radiation Oncology

Public Release: 7-Jan-2015
Breast Cancer Research
Dartmouth develops prognostic test for E2F4 in breast cancer
By looking at the expression levels of downstream genes of the regulators in breast cancer, Dartmouth researchers have identified a gene signature in E2F4 that is predictive of estrogen receptor positive (ER+) breast cancer. The findings, published in Breast Cancer Research, define a new opportunity for personalizing medicine for women whose Oncotype DX assay results classify them as of 'intermediate-risk for recurrence.'
American Cancer Society Research, Centers of Biomedical Research Excellence, Geisel School of Medicine at Dartmouth College

Contact: Kirk Cassels
kirk.A.Cassels@Hitchcock.org
603-653-6177
The Geisel School of Medicine at Dartmouth

Public Release: 7-Jan-2015
Tobacco Control
Study: Campus debit cards let students buy cigarettes with parents' money
A University of Colorado Cancer Center study published in the British Medical Journal: Tobacco Control shows that of the top 100 universities as ranked by US News and World Report, 11 allow tobacco sales and 13 allow e-cigarette sales on 'campus cash' debit cards that are commonly prepaid by parents.

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 6-Jan-2015
British Journal of Cancer
More than a third of people with abnormal results drop out of bowel cancer screening
Almost 40 percent of people who have abnormal results from bowel cancer screening tests and are referred for further investigation ignore their next screening invitation two years later.

Contact: Emily Head
emily.head@cancer.org.uk
44-203-469-6189
Cancer Research UK

Public Release: 6-Jan-2015
Science Signaling
Researchers uncover key cancer-promoting gene
One of the mysteries in cancer biology is how one protein, TGF-beta, can both stop cancer from forming and encourage its aggressive growth. Now, researchers at the University of Michigan Comprehensive Cancer Center have uncovered a key gene that may explain this paradox and provide a potential target for treatment.
NIH/National Cancer Institute, National Science Foundation

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 6-Jan-2015
Advanced Materials
'Flying carpet' technique uses graphene to deliver one-two punch of anticancer drugs
An international team of researchers has developed a drug delivery technique that utilizes graphene strips as 'flying carpets' to deliver two anticancer drugs sequentially to cancer cells, with each drug targeting the distinct part of the cell where it will be most effective. The technique was found to perform better than either drug in isolation when tested in a mouse model targeting a human lung cancer tumor.

Contact: Matt Shipman
matt_shipman@ncsu.edu
919-515-6386
North Carolina State University

Public Release: 6-Jan-2015
International Journal of Cancer
Study suggests that dopamine is a safe anti-angiogenic drug in cancer treatment
A new study suggests that dopamine -- an inexpensive drug currently used to treat heart, vascular and kidney disorders -- can be safely used in cancer treatment to curb the growth of blood vessels in tumors.
NIH/National Cancer Institute

Contact: Darrell E. Ward
darrell.ward@osumc.edu
614-293-3737
Ohio State University Wexner Medical Center

Public Release: 6-Jan-2015
Cell Metabolism
Targeting fatty acids may be treatment strategy for arthritis, leukemia
Enzymes linked to diabetes and obesity appear to play key roles in arthritis and leukemia, potentially opening up new avenues for treating these diverse diseases, according to researchers at Washington University School of Medicine in St. Louis.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, National Center for Research Resources

Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine

Public Release: 6-Jan-2015
Journal of Infectious Diseases
Ben-Gurion University researchers discover that AAT drug may prevent deadly infections
In the study, mice were directly infected with highly lethal live bacteria, sepsis and peritonitis. The initial aim was to exclude the possibility that AAT, might worsen infections in patients who are being treated with the drug. AAT is currently being used to treat new clinical indications like type 1 diabetes, emphysema and graft versus host disease. Instead, the BGU research group unexpectedly discovered that the treated mice combatted these lethal infections better than the untreated mice.

Contact: Andrew Lavin
andrewlavin@alavin.com
516-353-2505
American Associates, Ben-Gurion University of the Negev

Public Release: 6-Jan-2015
Prostate Cancer and Prostatic Disease
Novel imaging technique improves prostate cancer detection
In 2014, prostate cancer was the leading cause of newly diagnosed cancers in men and the second leading cause of cancer death in men. A team of scientists and physicians from the University of California, San Diego School of Medicine, with counterparts at University of California, Los Angeles, describe a novel imaging technique that measurably improves upon current prostate imaging -- and may have significant implications for how patients with prostate cancer are ultimately treated.
NIH/National Institute of Biomedical Imaging and Bioengineering, Department of Defense, Prostate Cancer Research Program, American Cancer Society, UC San Diego Clinician Scientist Program.

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Showing releases 1076-1100 out of 1330.

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