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Public Release: 25-Mar-2014
Treatment helps reduce risk of esophagus disorder progressing to cancer
Among patients with the condition known as Barrett's esophagus, treatment of abnormal cells with radiofrequency ablation (use of heat applied through an endoscope to destroy cells) resulted in a reduced risk of this condition progressing to cancer, according to a study in the March 26 issue of JAMA.

Contact: Jacques J. Bergman, M.D., Ph.D.
The JAMA Network Journals

Public Release: 24-Mar-2014
Proceedings of the National Academy of Sciences
Deletion of FAT10 gene reduces body fat, slows down aging in mice
A single gene appears to play a crucial role in coordinating the immune system and metabolism, and deleting the gene in mice reduces body fat and extends lifespan, according to new research by scientists at the Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University and Yale University School of Medicine.
National Institutes of Health

Contact: Andrea Grossman
Tufts University, Health Sciences Campus

Public Release: 24-Mar-2014
International Journal of Radiation Oncology
Radiation therapy and cancer vaccines: Timing is everything
Combining radiation with immnotherapy can boost cancer killing. Now a team from Thomas Jefferson University has shown that the boost works best when the therapies are sequenced correctly.

Contact: Edyta Zielinska
Thomas Jefferson University

Public Release: 24-Mar-2014
Society of Interventional Radiology 39th Annual Scientific Meeting
Journal of Vascular and Interventional Radiology
Y-90 provides new, safe treatment for metastatic breast cancer
A minimally invasive treatment that delivers cancer-killing radiation directly to tumors shows promise in treating breast cancer that has spread to the liver when no other treatment options remain. The outpatient treatment, called yttrium-90 (Y-90) radioembolization, was safe and provided disease stabilization in 98.5 percent of the women's treated liver tumors.

Contact: Ellen Acconcia
Society of Interventional Radiology

Public Release: 24-Mar-2014
72nd Annual Meeting of the American Academy of Dermatology
Increased awareness about skin cancer needed for minorities
More awareness about skin cancer is needed for minorities because they believe they are at low risk of developing it, says Henry Ford Hospital dermatologist Diane Jackson-Richards, M.D.

Contact: David Olejarz
Henry Ford Health System

Public Release: 24-Mar-2014
Journal of Cell Biology
p53 cuts off invading cancer cells
The tumor suppressor p53 does all it can to prevent oncogenes from transforming normal cells into tumor cells. Sometimes oncogenes manage to initiate tumor development in the presence of p53, but the tumor suppressor doesn't give up and focuses its efforts instead on limiting the tumor's ability to invade and metastasize. Researchers uncover one way that p53 acts to prevent cancer cell invasion.
National Research Foundation Singapore, Ministry of Education Singapore, and others

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 24-Mar-2014
Society of Interventional Radiology 39th Annual Scientific Meeting
Journal of Vascular and Interventional Radiology
New implant shows promise for painful osteoporotic spine fractures
Individuals suffering from spinal fractures -- caused by osteoporosis or weakened bones -- now have another option to reduce pain, restore function and improve quality of life, according to a study of 300 patients treated with a new type of vertebral augmentation. Results of a randomized, controlled multicenter trial on a new implant treatment for vertebral compression fractures are being reported for the first time at the Society of Interventional Radiology's 39th Annual Scientific Meeting.

Contact: Ellen Acconcia
Society of Interventional Radiology

Public Release: 24-Mar-2014
Bundled payments come to gastroenterology
Patients want physicians to provide high-quality care and the health system requires good value for physician work. To help gastroenterologists achieve these goals, the American Gastroenterological Association (AGA) has developed a colonoscopy bundled payment model, which has been published in Gastroenterology, the official journal of the AGA.

Contact: Aimee Frank
American Gastroenterological Association

Public Release: 24-Mar-2014
Clinical Genetics
Researchers issue state-of-the-state on genetic-based testing and treatment for breast cancer
Dartmouth researchers at its Norris Cotton Cancer Center have compiled a review of the role that information gathered through genetic testing plays in the diagnosis and treatment of breast cancer. The paper entitled 'Personalized Therapy for Breast Cancer' was accepted on March 17, 2014, for publication in Clinical Genetics. The paper discusses targeted therapies, new biomarkers, and the quality of commercially available testing methods.

Contact: Donna Dubuc
The Geisel School of Medicine at Dartmouth

Public Release: 24-Mar-2014
Journal of Clinical Oncology
Oncologists differ widely on offering cancer gene testing, study finds
Many cancer researchers believe that cutting-edge advances in genomics will pave the way for personalized or 'precision' cancer medicine for all patients in the near future. A new study by researchers at Dana-Farber Cancer Institute, however, suggest that not all doctors are ready to embrace tests that look for hundreds of DNA changes in patients' tumor samples, while others plan to offer this type of cancer gene testing to most of their patients. The findings are published in the Journal of Clinical Oncology.
NIH/National Human Genome Research Institute, American Cancer Society

Contact: Anne Doerr
Dana-Farber Cancer Institute

Public Release: 24-Mar-2014
Advanced Functional Materials
Hot nanoparticles for cancer treatments
Nanoparticles have a great deal of potential in medicine: for diagnostics, as a vehicle for active substances or a tool to kill off tumours using heat. ETH Zurich researchers have now developed particles that are relatively easy to produce and have a wide range of applications.

Contact: Georgios Sotiriou
ETH Zurich

Public Release: 24-Mar-2014
Gene implicated in progression and relapse of deadly breast cancer finding points to potential Achilles' heel in triple negative breast cancer
Scientists from Weill Cornell Medical College and Houston Methodist have found that a gene previously unassociated with breast cancer plays a pivotal role in the growth and progression of the triple negative form of the disease, a particularly deadly strain that often has few treatment options. Their research, published in this week's Nature, suggests that targeting the gene may be a new approach to treating the disease.

Contact: Jen Gundersen
Weill Cornell Medical College

Public Release: 24-Mar-2014
Use of mood-stabilizing drug linked with reduced risk of developing head and neck cancer
A new study indicates that a commonly used mood stabilizing drug may help prevent head and neck cancer. The study is published early online in Cancer, a peer-reviewed journal of the American Cancer Society.

Contact: Evelyn Martinez

Public Release: 23-Mar-2014
Leukemia caused by chromosome catastrophe
Researchers have found that people born with a rare abnormality of their chromosomes have a 2,700-fold increased risk of a rare childhood leukemia. In this abnormality, two specific chromosomes are fused together but become prone to catastrophic shattering.
Wellcome Trust, Leukaemia and Lymphoma Research Specialist Programme, FWO, European Research Council

Contact: Mary Clarke
Wellcome Trust Sanger Institute

Public Release: 23-Mar-2014
Nature Structural & Molecular Biology
Mass. General study identifies path to safer drugs for heart disease, cancer
Massachusetts General Hospital investigators may have found a way to solve a problem that has plagued a group of drugs called ligand-mimicking integrin inhibitors, which have the potential to treat conditions ranging from heart attacks to cancer metastasis.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Sue McGreevey
Massachusetts General Hospital

Public Release: 23-Mar-2014
Nature Genetics
TGen-led study discovers genetic cause of rare type of ovarian cancer
The cause of a rare type of ovarian cancer that most often strikes girls and young women has been uncovered by an international research team led by the Translational Genomics Research Institute, according to a study published online today by the renowned scientific journal, Nature Genetics. The findings revealed a 'genetic superhighway' mutation in a gene found in the overwhelming majority of patients with small cell carcinoma of the ovary, hypercalcemic type, or SCCOHT.

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 23-Mar-2014
Nature Methods
'MaMTH' advance: New technology sheds light on protein interactions
Scientists have a better way to study human proteins -- large molecules that are part of every cell in the body -- thanks to a new technology developed by University of Toronto researchers. The technology tracks a class of proteins called membrane proteins as they interact with other proteins to either maintain health or contribute to disease.
Ontario Genomics Institute, Canadian Institutes of Health Research, Canadian Cancer Society

Contact: Jim Oldfield
University of Toronto

Public Release: 23-Mar-2014
Society of Gynecological Oncology 45th Annual Meeting on Women's Cancer
HPV eradicated by AHCC supplement, preclinical study suggests
HPV, human papilloma virus, was eradicated by AHCC, a Japanese mushroom extract, in vivo and in vitro, in preclinical research presented by Judith A. Smith, PharmD., at Society of Gynecological Oncology 45th Annual Meeting on Women's Cancer in Tampa. These data suggest AHCC can eliminate HPV infections and may have a role in the prevention of HPV-related cancers. A confirmatory pilot study in HPV+ women is underway at UTHealth Women's Center.

Contact: John Carney or Julie McQuain
JMPR Associates, Inc.

Public Release: 22-Mar-2014
Society of Gynecology Oncology Annual Conference
Gynecologic Oncology
Bariatric surgery decreases risk of uterine cancer
Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center report that bariatric surgery resulting in dramatic weight loss in formerly severely obese women reduces the risk of endometrial (uterine) cancer by 71 percent and as much as 81 percent if normal weight is maintained after surgery.

Contact: Scott LaFee
University of California - San Diego

Public Release: 21-Mar-2014
The 9th European Breast Cancer Conference (EBCC-9)
A third of women might benefit from more frequent mammograms
A study of over 50,000 women participating in the United Kingdom NHS Breast Screening Programme has found that, while three-yearly screening intervals are appropriate for the majority of women, approximately one third of women are at higher risk of developing cancer and might benefit from more frequent mammograms. The research is presented at the 9th European Breast Cancer Conference.
National Institute for Health Research, Genesis Breast Cancer Prevention

Contact: Emma Mason
ECCO-the European CanCer Organisation

Public Release: 21-Mar-2014
The 9th European Breast Cancer Conference (EBCC-9)
Harms outweigh benefits for women aged 70 and over in national breast cancer screening programs
Extending national breast cancer screening programs to women over the age of 70 does not result in a decrease in the numbers of cancers detected at advanced stages, according to new research from the Netherlands.

Contact: Emma Mason
ECCO-the European CanCer Organisation

Public Release: 21-Mar-2014
The 9th European Breast Cancer Conference (EBCC-9)
Significant variations between NHS hospitals in adverse outcomes for treatment of DCIS
Analysis of data from the United Kingdom NHS Breast Screening Programme has shown significant variations in the outcomes of treatment for women with ductal carcinoma in situ between United Kingdom hospitals, according to research presented at the European Breast Cancer Conference.
NHS Breast Screening Programme, Public Health England

Contact: Emma Mason
ECCO-the European CanCer Organisation

Public Release: 21-Mar-2014
Journal of Thoracic Oncology
Characteristics of lung cancers arising in germline EGFR T790M mutation carriers
Two studies are providing new insight into germline epidermal growth factor receptor T790M mutation in familial non-small cell lung cancer. The findings suggest the need for tailored approaches for early detection and treatment, as well as for genetic testing to identify carriers.

Contact: Kristin Richeimer
International Association for the Study of Lung Cancer

Public Release: 21-Mar-2014
Journal of Clinical Oncology
Keck Medicine of USC research may point to better predictor of prostate cancer survival
New research by USC Norris Comprehensive Cancer Center scientists demonstrates that measuring circulating tumor cells -- the cells that spread cancer through the body -- may be a better predictor of patient survival than the prostate-specific antigen.
NIH/National Cancer Institute, Hope Foundation

Contact: Leslie Ridgeway
University of Southern California - Health Sciences

Public Release: 21-Mar-2014
Journal of National Cancer Institute
New method can diagnose a feared form of cancer
Pancreatic cancer is often detected at a late stage, which results in poor prognosis and limited treatment options. Researchers at The University of Gothenburg, Sweden, have now developed a method which identifies the cancer's visible precursors with 97 percent certainty. The method, which is expected to aid in the early discovery of the cancer as well as minimize the risk of unnecessary surgery, may be introduced in patient care within five years.

Contact: Karolina Jabbar
University of Gothenburg

Showing releases 1076-1100 out of 1242.

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