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Showing releases 1076-1100 out of 1216. << < 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 > >>
Public Release: 25-Feb-2013
 Journal of the American College of SurgeonsBreast cancer patients' fear of developing lymphedema far exceeds risk A new study published in the March issue of the Journal of the American College of Surgeons suggests that the vast majority of women who undergo breast cancer operations worry about developing lymphedema, but their fear far exceeds their actual risk of developing the condition. 
Bankhead Coley Florida Cancer Research Program
Contact: Sally Garneski
Public Release: 25-Feb-2013
CancerScreening could avert 12,000 lung cancer deaths each year in the United States Screening for lung cancer with low-dose computed tomography (LDCT) in all screening-eligible current and former smokers has the potential to avert approximately 12,000 lung cancer deaths each year in the United States. That is the conclusion of a new analysis published early online in CANCER, a peer-reviewed journal of the American Cancer Society. By providing a national estimate of potentially avertable lung cancer deaths, the study will help policy makers better understand the possible benefits of LDCT lung cancer screening. Contact: Amy Molnar
Public Release: 25-Feb-2013
PediatricsMajority of Missouri tan salons allow pre-teens A survey of tanning salon operators in Missouri shows that 65 percent would allow children as young as 10 to 12 years old to use tanning beds. That's despite evidence that any tanning bed use increases the risk of all skin cancers, including melanoma, the deadliest form of skin cancer, later in life.
NIH/National Cancer Institute
Contact: Jim Goodwin
Public Release: 25-Feb-2013
PLOS ONESmall molecules in the blood might gauge radiation effects after exposure Researchers have identified molecules in the blood that might gauge the likelihood of radiation illness after exposure to ionizing radiation. The animal study shows that radiation predictably alters levels of certain molecules in the blood. If verified in human subjects, the findings could lead to new methods for rapidly identifying people at risk for acute radiation syndrome after occupational exposures or nuclear reactor accidents, and they might help doctors plan radiation therapy for patients.
NIH/National Cancer Institute, Brain Tumor Funders Collaborative
Contact: Darrell E. Ward
Public Release: 25-Feb-2013
BMC MedicineCell scaffolding protein fascin-1 is hijacked by cancer A protein involved in the internal cell scaffold is associated with increased risk of metastasis and mortality in a range of common cancers finds a meta-analysis published in Biomed Central's open access journal BMC Medicine. Contact: Hilary Glover
Public Release: 24-Feb-2013
Nature Structural & Molecular BiologyNew type of gene that regulates tumor suppressor PTEN identified Researchers at Karolinska Institutet in Sweden have identified a new so-called pseudogene that regulates the tumor-suppressing PTEN gene. They hope that this pseudogene will be able to control PTEN to reverse the tumor process, make the cancer tumor more sensitive to chemotherapy and to prevent the development of resistance.
Swedish Childhood Cancer Foundation, Swedish Research Council, and others
Contact: The Press Office
Public Release: 24-Feb-2013
Nature Structural and Molecular BiologyScientists find surprising new influence on cancer genes Small stretches of DNA in the human genome are known as "pseudogenes" because, while their sequences are nearly identical to those of various genes, they have long been thought to be non-coding "junk" DNA. But now, a new study led by scientists at the Scripps Research Institute shows how pseudogenes can regulate the activity of a cancer-related gene called PTEN. The study also shows that pseudogenes can be targeted to control PTEN's activity.
National Institutes of Health, Swedish Childhood Cancer Foundation, Swedish Cancer Society, Radiumhemmets Forskningsfonder
Contact: Mika Ono
Public Release: 24-Feb-2013
NatureResearchers at IRB Barcelona discover a general mechanism that accelerates tumor development ICREA professor Raúl Méndez publishes a study in Nature describing how the CPBE1 protein "takes the brakes off" the production of proteins associated with the cell switch from being healthy to tumorous. The study highlights CPEB proteins as promising targets, thus opening up a new and unexplored therapeutic window. The lab has developed a system for screening compounds that impede the action of CPEB proteins in tumors. Contact: Sònia Armengou
Public Release: 24-Feb-2013
NatureDistinct niches in bone marrow nurture blood stem cells In research that could one day improve the success of stem cell transplants and chemotherapy, scientists have found that distinct niches exist in bone marrow to nurture different types of blood stem cells.
National Institutes of Health
Contact: Caroline Arbanas
Public Release: 24-Feb-2013
NatureScientists find bone-marrow environment that helps produce infection-fighting T and B cells The Children's Medical Center Research Institute at UT Southwestern has deepened the understanding of the environment within bone marrow that nurtures stem cells, this time identifying the biological setting for specialized blood-forming cells that produce the infection-fighting white blood cells known as T cells and B cells.
Howard Hughes Medical Institute, NIH/National Heart, Lung, and Blood Institute
Contact: Jeff Carlton
Public Release: 24-Feb-2013
Nature MethodsAnalytical trick accelerates protein studies Researchers at the University of Wisconsin-Madison have found a new way to accelerate a workhorse instrument that identifies proteins. The high-speed technique could help diagnose cancer sooner and point to new drugs for treating a wide range of conditions. Contact: Joshua Coon
Public Release: 22-Feb-2013
PLOS ONEUNC-led study documents head and neck cancer molecular tumor subtypes By analyzing data from DNA microarrays, a UNC-led team has completed a study that confirms the presence of four molecular classes of the disease and extends previous results by suggesting that there may be an underlying connection between the molecular classes and observed genomic events, some of which affect known cancer genes.
National Institutes of Health, UNC Lineberger Comprehensive Cancer Center, University Cancer Research Fund
Contact: Dianne Shaw
Public Release: 22-Feb-2013
Journal of Clinical InvestigationJCI early table of contents for Feb. 22, 2013 This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, Feb. 22, 2013, in the JCI: How to mend a broken heart: advances in parthenogenic stem cells; Pulmonary fibrosis: between a ROCK and a hard place; Epigenetic alterations reprogram pancreatic cells to secrete insulin; Brain "clean-up crew" captured by MRI; and many more. Contact: Jillian Hurst
Public Release: 22-Feb-2013
Science SignalingFlipping the 'off' switch on cell growth A protein known for turning on genes to help cells survive low-oxygen conditions also slows down the copying of new DNA strands, thus shutting down the growth of new cells, Johns Hopkins researchers report. Their discovery has wide-ranging implications, they say, given the importance of this copying -- known as DNA replication -- and new cell growth to many of the body's functions and in such diseases as cancer.
US Public Health Service, NIH/National Heart, Lung, and Blood Institute, NIH/National Institute of General Medical Sciences, American Heart Association, Susan G. Komen Foundation
Contact: Shawna Williams
Public Release: 22-Feb-2013
Angewandte ChemieUCLA researchers further refine 'NanoVelcro' device to grab single cancer cells from blood Researchers at UCLA report that they have refined a method they previously developed for capturing and analyzing cancer cells that break away from patients' tumors and circulate in the blood. With the improvements to their device, which uses a Velcro-like nanoscale technology, they can now detect and isolate single cancer cells from patient blood samples for analysis. Contact: Shaun Mason
Public Release: 21-Feb-2013
Journal of Nutritional BiochemistryOmega-3s inhibit breast cancer tumor growth, study finds A lifelong diet rich in omega-3 fatty acids can inhibit growth of breast cancer tumors by 30 percent, according to new research from the University of Guelph. The study, published recently in the Journal of Nutritional Biochemistry, is believed to be the first to provide unequivocal evidence that omega-3s reduce cancer risk.
Canadian Institutes of Health Research/Canadian Breast Cancer Research Alliance, Canada Foundation for Innovation, Ontario Research Fund
Contact: David Ma
Public Release: 21-Feb-2013
Cancer DiscoveryBiomarker may identify neuroblastomas with sensitivity to BET bromodomain inhibitors The MYCN gene is commonly amplified in neuroblastoma and associated with poor prognosis. A BET bromodomain inhibitor downregulated MYCN expression. The drug prolonged survival in three animal models of MYCN-amplified neuroblastoma.
Stand Up To Cancer
Contact: Jeremy Moore
Public Release: 21-Feb-2013
European Journal of NeuroscienceRutgers neuroscientist sheds light on cause for 'chemo brain' It's not unusual for cancer patients being treated with chemotherapy to complain about not being able to think clearly, connect thoughts or concentrate on daily tasks. The complaint -- often referred to as chemo-brain -- is common. The scientific cause, however, has been difficult to pinpoint. New research by Rutgers University behavioral neuroscientist Tracey Shors offers clues for this fog-like condition, medically known as chemotherapy-induced cognitive impairment. Contact: Robin Lally
Public Release: 21-Feb-2013
SensorsSniffing out the side effects of radiotherapy may soon be possible Researchers at the University of Warwick and The Royal Marsden NHS Foundation Trust have completed a study that may lead to clinicians being able to more accurately predict which patients will suffer from the side effects of radiotherapy. Contact: Luke Harrison
Public Release: 21-Feb-2013
Cell ReportsStudy reveals new clues to Epstein-Barr virus Epstein-Barr virus (EBV) affects more than 90 percent of the population worldwide and was the first human virus found to be associated with cancer. Now, researchers from Beth Israel Deaconess Medical Center have broadened the understanding of this widespread infection with their discovery of a second B-cell attachment receptor for EBV.
National Institutes of Health, American Heart Association, St. Baldrick's Foundation, Cancer Research Institute
Contact: Bonnie Prescott
Public Release: 21-Feb-2013
Journal of Thoracic OncologyLocal therapy followed by treatment with EGFR TKI is well tolerated A recent study published in the March 2013 issue of the International Association for the Study of Lung Cancer's Journal of Thoracic Oncology, found that EGFR- mutant lung cancers with acquired resistance to EGFR TKI therapy are amenable to local therapy to treat oligometastatic disease when used in conjunction with continued EGFR inhibition. Contact: Kristal Griffith
Public Release: 21-Feb-2013
Journal of Thoracic OncologyGreater representation of elderly patients in Phase III trials are needed A recent study published in the March 2013 issue of the International Association for the Study of Lung Cancer's Journal of Thoracic Oncology, investigated the degree to which exclusion or underrepresentation of elderly occurs in practice-changing clinical trials in advanced NSCLC. Researchers conclude that greater representation of elderly patients in phase III trials is required to better define evidence-based paradigms in the increasingly elderly NSCLC population. Contact: Kristal Griffith
Public Release: 20-Feb-2013
Technology in Cancer Research and TreatmentPreclinical study shows potential of new technologies to detect response to cancer therapy earlier This study found that by using two non-invasive technologies, a patient's response to therapy can be detected earlier than by relying on tumor volume changes.
National Institutes of Health, University of North Carolina Lineberger Comprehensive Cancer Center, American Cancer Society
Contact: Dianne Shaw
Public Release: 20-Feb-2013
GastroenterologyResearchers identify variations in 4 genes associated with an increased risk of colorectal cancer An international research team co-led by cancer prevention researcher Ulrike "Riki" Peters, Ph.D., M.P.H., and biostatistician Li Hsu, Ph.D., at Fred Hutchinson Cancer Research Center has identified variations in four genes that are linked to an increased risk of colorectal cancer. Peters and colleagues from 40 institutes throughout the world published their findings online ahead of the April print issue of Gastroenterology.
NIH/National Cancer Institute, National Institutes of Health, US Department of Health and Human Services
Contact: Kristen Woodward
Public Release: 20-Feb-2013
Endocrine-Related CancerMushroom-supplemented soybean extract shows therapeutic promise for advanced prostate cancer A natural, nontoxic product called genistein-combined polysaccharide, or GCP, which is commercially available in health stores, could help lengthen the life expectancy of certain prostate cancer patients, UC Davis researchers have found.
Biomedical Laboratory Research and Development service Merit Award, Department of Veterans Affairs
Contact: Dorsey Griffith
Showing releases 1076-1100 out of 1216. << < 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 > >>
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