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Public Release: 11-Jun-2012
2012 Society of Nuclear Medicine Annual Meeting
Have no fear: Most cases of thyroid cancer do not affect survival
Research presented at the Society of Nuclear Medicine's 59th Annual Meeting reveals that patients with differentiated thyroid cancer live as long as people in perfect health, unless they are in the minority and have reached the most advanced stages of disease. Survival did not vary based on age, sex, or even if patients' cancer had reached the beginning of stage IV.

Contact: Susan Martonik
smartonik@snm.org
703-652-6773
Society of Nuclear Medicine

Public Release: 11-Jun-2012
2012 Society of Nuclear Medicine Annual Meeting
PET imaging could lead to better care for neuroendocrine cancer
A method of molecular imaging that pinpoints hormonally active tissues in the body could change the course of treatment for a remarkable number of neuroendocrine cancer patients, say researchers at the Society of Nuclear Medicine's 59th Annual Meeting.

Contact: Susan Martonik
smartonik@snm.org
703-652-6773
Society of Nuclear Medicine

Public Release: 10-Jun-2012
Nature
Decoding DNA finds breast tumor signatures that predict treatment response
Decoding the DNA of patients with advanced breast cancer has allowed scientists to identify distinct cancer "signatures" that could help predict which women are most likely to benefit from estrogen-lowering therapy, while sparing others from unnecessary treatment.
NIH/National Cancer Institute, NIH/National Human Genome Research Institute, Susan G. Komen for the Cure, Fashion Footwear Charitable Foundation Inc.

Contact: Caroline Arbanas
arbanasc@wustl.edu
314-286-0109
Washington University School of Medicine

Public Release: 10-Jun-2012
Euroanaesthesia 2012
Quick, simple test developed to identify patients who will not respond to the painkiller tramadol
French researchers have found a way to identify quickly the five-ten percent of patients in whom the commonly used painkiller, tramadol, does not work effectively. A simple blood test can produce a result within a few hours, enabling doctors to switch a non-responding patient on to another painkiller, such as morphine, which will be able to work in these patients. The research will be presented to the European Anaesthesiology Congress in Paris on Sunday.
Hospital Clinical Research Program

Contact: Emma Mason
wordmason@mac.com
ESA (European Society of Anaesthesiology)

Public Release: 10-Jun-2012
Nature Chemical Biology
Scripps Research scientists develop new tools to unveil mystery of the 'glycome'
Scientists at the Scripps Research Institute have developed chemical compounds that can make key modifications to common sugar molecules ("glycans"), which are found on the surface of all cells in our body.
National Institutes of Health

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

Public Release: 8-Jun-2012
Journal of the National Cancer Institute
Probing the mechanism of ADAM28-mediated cancer metastasis
ADAM28, a metalloproteinase belonging to the ADAM gene family, cleaves the von Willebrand factor (VWF) and inhibits VWF-mediated cancer cell apoptosis, thereby enhancing lung metastases, so inhibiting its expression gives a substantial reduction in lung metastases, according to a study published June 8 in the Journal of The National Cancer Institute.

Contact: Zachary Rathner
Zachary.Rathner@oup.com
301-841-1286
Journal of the National Cancer Institute

Public Release: 8-Jun-2012
ASTRO chairman to testify at CARE Act hearing
American Society for Radiation Oncology Chairman Leonard Gunderson, M.D., M.S., FASTRO, will testify before the House Committee on Energy and Commerce Subcommittee on Health today on provisions of the Consistency, Accuracy, Responsibility, and Excellence in Medical Imaging and Radiation Therapy Act of 2011 (CARE Act) related to training and credentialing for medical imaging and radiation therapy technologists.

Contact: Nicole Napoli
nicolen@astro.org
703-839-7336
American Society for Radiation Oncology

Public Release: 8-Jun-2012
Cancer Immunology, Immunotherapy
Moffitt Cancer Center researchers develop and test new anti-cancer vaccine
Researchers at Moffitt Cancer Center have developed and tested in mice a synthetic vaccine and found it effective in killing human papillomavirus-derived cancer, a virus linked to cervical cancers among others. The research was published in a recent issue of Cancer Immunology, Immunotherapy.
National Institutes of Health

Contact: Patty Kim
patty.kim@moffitt.org
813-745-7322
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 8-Jun-2012
Journal of Cell Science
Overexpression of proteins 14-3-3 related to chemotherapy resistance
Certain proteins, such as 14-3-3, conserve their basic functions of cell cycle control in diverse organisms, from worms to humans. In a study led by Julián Cerón and Simó Schwartz Jr, researchers from the Bellvitge Biomedical Research Institute and the Research Institute of Vall d'Hebron respectively, have described germ line functions of par-5, which is one of the two 14-3-3 proteins existing in Caenorhabditis elegans, worms used as experimental model in genetic studies.

Contact: Raül Toran
comunicacio@idibell.cat
IDIBELL-Bellvitge Biomedical Research Institute

Public Release: 8-Jun-2012
2012 Society of Nuclear Medicine Annual Meeting
Piramal Imaging to present data at Society for Nuclear Medicine Annual Meeting
Piramal Imaging SA, a subsidiary of Piramal Healthcare Limited, will present data on several compounds from its molecular imaging portfolio at the Society of Nuclear Medicine's 59th annual meeting in Miami Beach, Fla., from June 9 - 13. Data from five florbetaben studies will be featured, including results from a pivotal Phase III trial which will provide the basis for regulatory submission later this year.

Contact: Julie Armour
julie.armour@ketchum.com
908-656-5887
Ketchum New York

Public Release: 7-Jun-2012
Journal of Health Care for the Poor and Underserved
2-1-1 could be effective tool in fighting cancer disparities
The 2-1-1 phone information and referral system could be a key partner in efforts to reduce cancer disparities affecting low-income and racial and ethnic minorities in the US, finds a new study by Jason Purnell, Ph.D., assistant professor of public health at the Brown School at Washington University in St. Louis.

Contact: Jessica Martin
jessica_martin@wustl.edu
314-935-5251
Washington University in St. Louis

Public Release: 7-Jun-2012
PLOS Genetics
Study sheds new light on role of genetic mutations in colon cancer development
In exploring the genetics of mitochondria -- the powerhouse of the cell -- researchers at Fred Hutchinson Cancer Research Center have stumbled upon a finding that challenges previously held beliefs about the role of mutations in cancer development. For the first time, researchers have found that the number of new mutations are significantly lower in cancers than in normal cells.
NIH/National Institute of Environmental Health Sciences, Ellison Medical Foundation, Fred Hutchinson Cancer Research Center

Contact: Kristen Woodward
kwoodwar@fhcrc.org
206-667-5095
Fred Hutchinson Cancer Research Center

Public Release: 7-Jun-2012
Nature
Mount Sinai researchers develop a multi-target approach to treating tumors
Researchers from Mount Sinai School of Medicine developed a cancer model built in the fruit fly Drosophila, then used it to create a whole new approach to the discovery of cancer treatments. The result is an investigational compound AD80 that precisely targets multiple cancer genes.

Contact: Mount Sinai Press Office
newsmedia@mssm.edu
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 7-Jun-2012
Science
New discovery provides insight on long-standing pregnancy mystery
Researchers at NYU School of Medicine have made an important discovery that partially answers the long-standing question of why a mother's immune system does not reject a developing fetus as foreign tissue.
National Institutes of Health, American Cancer Society

Contact: Jessica Guenzel
jessica.guenzel@nyumc.org
212-404-3591
NYU Langone Medical Center / New York University School of Medicine

Public Release: 6-Jun-2012
Biology of Reproduction
3 types of fetal cells can migrate into maternal organs during pregnancy
A pregnant woman's blood stream contains not only her own cells, but a small number of her child's, as well, and some of them remain in her internal organs long after the baby is born. Understanding the origin and identity of these cells is vital to understanding their potential effects on a mother's long-term health.
NIH/National Institute of Child Health and Human Development, Provost Fund at Tufts University, Sackler Dean's Fellowship Award

Contact: Jeremy Lechan
jlechan@tuftsmedicalcenter.org
617-636-0104
Society for the Study of Reproduction

Public Release: 6-Jun-2012
Proceedings of the National Academy of Sciences
Researchers at IRB Barcelona uncover new clues about the origin of cancer
A study by researchers at the Institute for Research in Biomedicine, in collaboration with scientists at the Memorial Sloan Kettering Cancer Center, reveals new information about the origin of tumors. In this study, the scientists postulate that the initiation of a tumor and the type and aggressivity of the same depend on a specific combination of defects in several processes that safeguard cell integrity, such as DNA repair pathways and cell cycle check-points.

Contact: Sňnia Armengou
sonia.armengou@irbbarcelona.org
34-934-037-255
Institute for Research in Biomedicine (IRB Barcelona)

Public Release: 6-Jun-2012
New England Journal of Medicine
New drug found effective against rare form of basal cell skin cancer
A clinical study has demonstrated that a new drug, a targeted molecular therapy called vismodegib (trade name Erivedge), can dramatically shrink basal cell skin cancers and prevent the formation of new ones, in patients with basal cell nevus syndrome. The phase II clinical study, led by researchers at NewYork-Presbyterian Hospital/Columbia University Medical Center and Children's Hospital of Oakland Research Institute, was published today in the online edition of the New England Journal of Medicine.
National Institutes of Health, NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases, Damon Runyon Cancer Research Foundation, Swim Across America Foundation, Genentech

Contact: Elizabeth Streich
estreich@columbia.edu
212-305-3689
Columbia University Medical Center

Public Release: 6-Jun-2012
European Physical Journal E
Modeling the demise of migrating brain tumor cells
An Israeli physicist has developed a theoretical model to simulate the evolution of highly proliferating brain tumor core cells subjected to treatment by alternating radio frequency electric field. The research, by Alexander Iomin from the Israel Institute of Technology Technion in Haifa, is about to be published in EPJ E. In another model, the author examines the possibility of enhancing the level of treatment by targeting the outer area of the tumor.

Contact: Janine Haubenreisser
janine.haubenreisser@springer.com
49-622-148-78414
Springer

Public Release: 6-Jun-2012
Disease Models & Mechanisms
UC Davis scientists find new role for P53 genetic mutation -- initiation of prostate cancer
A team of UC Davis investigators has found that a genetic mutation may play an important role in the development of prostate cancer.

Contact: Dorsey Griffith
dorsey.griffith@ucdmc.ucdavis.edu
916-734-9118
University of California - Davis Health System

Public Release: 6-Jun-2012
Cancer Research
HIV drug may slow down metastatic breast cancer, say researchers at Jefferson's Kimmel Cancer Center
The HIV drugs known as CCR5 antagonists may also help prevent aggressive breast cancers from metastasizing, researchers from the Kimmel Cancer Center at Jefferson suggest in a preclinical study published in a recent issue of Cancer Research.

Contact: Steve Graff
stephen.graff@jefferson.edu
215-955-5291
Thomas Jefferson University

Public Release: 5-Jun-2012
Nature Structural & Molecular Biology
Identified an anti-oncogene into an oncogene
A study coordinated by Manel Esteller, Director of the program of epigenetics and cancer biology at the Bellvitge Institute for Biomedical Research, Professor of genetics at the University of Barcelona and ICREA researcher, has discovered the existence of an antitumor molecule that originates within an oncogene. The finding is published this week in the Nature Structural & Molecular Biology journal.

Contact: Raül Toran
comunicacio@idibell.cat
IDIBELL-Bellvitge Biomedical Research Institute

Public Release: 5-Jun-2012
Blood
Type 2 diabetes linked to increased blood cancer risk, say Miriam Hospital researchers
A new meta-analysis by Miriam Hospital researchers reveals patients with type 2 diabetes have a 20 percent increased risk of developing blood cancers.
NIH/National Center for Research Resources

Contact: Jessica Collins Grimes
jgrimes2@lifespan.org
401-793-7484
Lifespan

Public Release: 5-Jun-2012
PETA to FDA: Don't let more animals suffer and die for tobacco products
PETA today submitted official comments to the Food and Drug Administration regarding the agency's Draft Guidance for Industry: Modified Risk Tobacco Product (MRTP) Applications, which, as currently written, will lead to animal studies being conducted in support of MRTP applications. PETA, along with hundreds of consumers who submitted comments to the FDA through an action alert on PETA's popular website, is calling on the FDA to amend its guidance to recommend using only modern, effective non-animal testing methods.

Contact: Jessica Sandler
JessicaS@peta.org
People for the Ethical Treatment of Animals

Public Release: 5-Jun-2012
New Firefly technology lights up more precise kidney sparing surgery
During kidney surgery, Firefly fluorescence used with the da Vinci robot lights up in "firefly green" the blood supply to the kidney and helps differentiate cancerous from healthy tissue. More patients can keep the healthy part of their kidney rather than losing the entire organ.

Contact: Marianne Worley
worleym@gunet.georgetown.edu
703-558-1287
MedStar Georgetown University Hospital

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