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Showing releases 1101-1125 out of 1352.

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Public Release: 5-Jan-2016
DHEA improves vaginal discomfort after menopause
A new phase III trial with positive results is taking intravaginal DHEA a step closer to governmental approval. The formulation could provide women who cannot or do not wish to use intravaginal estrogen with an effective vaginal alternative for easing vaginal symptoms and pain with sex after menopause. The trial results were published online today in Menopause, the journal of The North American Menopause Society.

Contact: Eileen Petridis
The North American Menopause Society (NAMS)

Public Release: 5-Jan-2016
Twin study estimates familial risks of 23 different cancers
A large new study of twins has found that having a twin sibling diagnosed with cancer poses an excess risk for the other twin to develop any form of cancer.
Ellison Foundation to Harvard T.H. Chan School of Public Health, Nordic Cancer Union

Contact: Todd Datz
Harvard T.H. Chan School of Public Health

Public Release: 5-Jan-2016
Long-term follow-up of risk of cancer among twins
In a long-term follow-up study among approximately 200,000 Nordic twin individuals, there was an increased cancer risk in twins whose co-twin was diagnosed with cancer, with an increased risk for cancer overall and for specific types of cancer, including prostate, melanoma, breast, ovary, and uterus, according to a study in the Jan. 5 issue of JAMA.

Contact: Lorelei A. Mucci
The JAMA Network Journals

Public Release: 4-Jan-2016
Gene thought to suppress cancer may actually promote spread of colorectal cancer
A gene that is known to suppress the growth and spread of many types of cancer has the opposite effect in some forms of colorectal cancer, University of Missouri School of Medicine researchers have found. It is a finding that may lay the foundation for new colorectal cancer treatments.
National Institutes of Health, Veterans Affairs Merit Award, University of Missouri Research Board Award, University of Missouri School of Medicine Bridge

Contact: Derek Thompson
University of Missouri-Columbia

Public Release: 4-Jan-2016
Journal of the Federation of American Societies for Experimental Biology
New paste prevents scarring caused by radiation therapy for cancer
An antiscarring paste when applied to the skin of mice halts fibrosis caused by the radiation used in cancer therapy.
National Institutes of Health, Laura and Isaac Perlmutter Cancer Center

Contact: Greg Williams
New York University

Public Release: 4-Jan-2016
Journal of Pain and Symptom Management
Racial bias may be conveyed by doctors' body language
Physicians give less compassionate nonverbal cues when treating seriously ill black patients compared with their white counterparts, a small University of Pittsburgh School of Medicine trial revealed. It is the first to look at such interactions in a time-pressured, end-of-life situation.
American Cancer Society, National Cancer Institute

Contact: Allison Hydzik
University of Pittsburgh Schools of the Health Sciences

Public Release: 4-Jan-2016
Journal of Urology
Prostate cancer surveillance criteria may not be accurate for African American men
A new study published in The Journal of Urology revealed that African American men with Gleason score 3+3=6 prostate cancer (PCa) produce less prostate specific antigen (PSA) and have significantly lower PSA density (PSAD) than Caucasian men. These findings could have important implications when selecting patients for inclusion in active PCa surveillance programs.

Contact: Linda Gruner
Elsevier Health Sciences

Public Release: 4-Jan-2016
BJU International
Prostate surgery patients may have unrealistic expectations concerning their recovery
Patients who have undergone radical prostatectomy often have largely unrealistic expectations with regard to their postoperative sexual function, new research shows.

Contact: Dawn Peters

Public Release: 4-Jan-2016
Journal of Hunger & Environmental Nutrition
Miriam Hospital, R.I. Community Food Bank study dispels belief healthy diets are costly
Research conducted by The Miriam Hospital and The Rhode Island Community Food Bank demonstrated that -- contrary to popular belief -- healthy diets rich in fruits and vegetables are affordable.

Contact: Elena Falcone-Relvas

Public Release: 4-Jan-2016
Annals of Neurology
Medical research influenced by training 'genealogy'
By analyzing peer-reviewed scientific papers that examined the effectiveness of a surgical procedure, researchers at University of California, San Diego School of Medicine provide evidence suggesting that the conclusions of these studies appear to be influenced by the authors' mentors and medical training.
UC San Diego/Czech Duck Research Fellowship in Neurosurgery

Contact: Heather Buschman
University of California - San Diego

Public Release: 4-Jan-2016
Journal of Thoracic Oncology
Improving access to clinical trials when biopsies are required
The requirement for tumor tissue specimens and associated analyses in order to participate in clinical trials appears to be a significant barrier to clinical trial enrollment and may delay treatment. Potential solutions to reducing or eliminating these barriers include routine tissue banking at diagnosis, easing use of available diagnostic samples, development of less invasive tests, faster turnaround time at central laboratories or allowing for local testing and more resources for timely tissue collection.

Contact: Jeff Wolf
International Association for the Study of Lung Cancer

Public Release: 3-Jan-2016
Nucleic Acids Research
Biggest database for cancer drug discovery goes 3-D
The world's largest database for cancer drug discovery has been revolutionized by adding 3-D structures of faulty proteins and maps of cancer's communication networks, according to Cancer Research UK-funded research published in Nucleic Acid Research today (Monday).
Cancer Research UK

Contact: Emma Rigby
Cancer Research UK

Public Release: 1-Jan-2016
Clinical Cancer Research
Three hits to fight lung cancer
A new study in mice has shown that cancers with KRAS-related gene mutations might benefit from a triple therapy with two experimental drugs plus radiation therapy.

Contact: Colleen Cordaro
Thomas Jefferson University

Public Release: 1-Jan-2016
Cancer Research
Sugar in western diets increases risk for breast cancer tumors and metastasis
The high amounts of dietary sugar in the typical western diet may increase the risk of breast cancer and metastasis to the lungs, according to a study at The University of Texas MD Anderson Cancer Center.

Contact: Ron Gilmore
University of Texas M. D. Anderson Cancer Center

Public Release: 31-Dec-2015
Cell Reports
Sylvester researchers describe role of STING protein in development of colorectal cancer
A new study published today by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine (Sylvester) reports on a key finding about the immune system's response to tumor development following studies on colorectal cancer. This is the first detailed examination of how the stimulator of interferon genes (STING) signaling pathway may play an important role in alerting the immune system to cellular transformation.

Contact: Patrick Bartosch
University of Miami Miller School of Medicine

Public Release: 30-Dec-2015
Journal of the National Cancer Institute
Virtual colonoscopy an alternative to FOB test & colonoscopy for colorectal cancer?
Colorectal cancer is the third most diagnosed cancer in the world, with population screening being recommended for early disease detection, however, the most optimal method to screen for the disease remains unknown.

Contact: Zachary Rathner
Oxford University Press USA

Public Release: 30-Dec-2015
New method for better treatment of breast cancer
A new study shows that a novel imaging-based method for defining appropriateness of breast cancer treatment is as accurate as the current standard-of-care and could reduce the need for invasive tissue sampling. The results suggest that the method might lead to more optimal treatment of individual patients.

Contact: Jens Sörensen
Uppsala University

Public Release: 30-Dec-2015
JAMA Oncology
T cells that recognize HER2 teceptor may prevent HER2+ breast cancer recurrence
Recurrence of HER2-positive breast cancer after treatment may be due to a specific and possibly cancer-induced weakness in the patient's immune system -- a weakness that in principle could be corrected with a HER2-targeted vaccine -- according to a new study.
National Institutes of Health

Contact: Katie Delach
University of Pennsylvania School of Medicine

Public Release: 30-Dec-2015
Plastic and Reconstructive Surgery
Travel distance is still a barrier to breast reconstruction after mastectomy
Long travel distances continue to be a significant obstacle to breast reconstruction after mastectomy for breast cancer, reports a study in the January issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons.

Contact: Connie Hughes
Wolters Kluwer Health

Public Release: 29-Dec-2015
Journal of the National Cancer Institute
Factors predicting low patient accrual in cancer clinical trials
Nearly one in four publicly sponsored cancer clinical trials fail to enroll enough participants to draw valid conclusions about treatments or techniques. Such trials represent a waste of scarce human and economic resources and contribute little to medical knowledge.

Contact: Zachary Rathner
Oxford University Press USA

Public Release: 29-Dec-2015
JAMA Oncology
New breast cancer drug may be effective against other types of cancer
Palbociclib, a new oral drug whose efficacy in combating breast cancer has been demonstrated alone and in combination with endocrine therapy, also has potential to combat other types of cancer, according to a literature review and additional original research conducted by experts at the Abramson Cancer Center in the University of Pennsylvania published this month in JAMA Oncology.
Pfizer Inc., National Institutes of Health

Contact: Steve Graff
University of Pennsylvania School of Medicine

Public Release: 28-Dec-2015
Journal of the National Cancer Institute
Breast cancer detection rate using ultrasound is shown to be comparable to mammography
The use of ultrasound in detecting breast cancer has been shown to be comparable in its sensitivity to that of mammography and should be considered when testing for the disease according to a study published Dec. 28 in the JNCI: Journal of the National Cancer Institute.

Contact: Zachary Rathner
Oxford University Press USA

Public Release: 28-Dec-2015
Proceedings of the National Academy of Sciences
Second contagious form of cancer found in Tasmanian devils
Transmissible cancers are believed to arise extremely rarely in nature. One of the few known transmissible cancers causes facial tumors in Tasmanian devils, and is threatening this species with extinction. Today, scientists report the discovery of a second transmissible cancer in Tasmanian devils. The discovery, published in Proceedings of the National Academy of Science, calls into question our current understanding of the processes that drive cancers to become transmissible.
Wellcome Trust, Australian Research Council, Dr Eric Guiler Tasmanian Devil Research Grants, Save the Tasmanian Devil Program

Contact: Craig Brierley
University of Cambridge

Public Release: 28-Dec-2015
Hypnosis may provide new option for 'awake surgery' for brain cancer
Could hypnosis help to reduce the psychological trauma associated with 'awake craniotomy' for brain cancers? A new 'hypnosedation' technique offers a new alternative for patients undergoing awake surgery for gliomas, suggests a study in the January issue of Neurosurgery, official journal of the Congress of Neurological Surgeons, published by Wolters Kluwer.

Contact: Connie Hughes
Wolters Kluwer Health

Public Release: 28-Dec-2015
Oral Oncology
Cell harm seen in lab tests of e-cigarettes
A lab team at the Veterans Affairs San Diego Healthcare System tested two types of electronic cigarettes and found they damaged cells in ways that could lead to cancer. The damage occurred even with nicotine-free versions of the products.
US Department of Veterans Affairs, National Institutes of Health, Brandon C. Gromada Head and Neck Cancer Foundation

Contact: Cindy C. Butler
Veterans Affairs Research Communications

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