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Showing releases 1101-1125 out of 1245.

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Public Release: 14-Jul-2014
Nature Communications
Wisconsin scientists find genetic recipe to turn stem cells to blood
The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality. Writing today in the journal Nature Communications, a group led by University of Wisconsin-Madison stem cell researcher Igor Slukvin reports the discovery of two genetic programs responsible for taking blank-slate stem cells and turning them into both red and the array of white cells that make up human blood.
National Institutes of Health, Charlotte Geyer Foundation

Contact: Igor Slukvin
islukvin@wisc.edu
608-263-0058
University of Wisconsin-Madison

Public Release: 14-Jul-2014
JAMA Internal Medicine
Prostate cancer is focus of 2 studies, commentary
Management of low-risk prostate cancer, which is unlikely to cause symptoms or affect survival if left untreated, varies widely among urologists and radiation oncologists, with patients whose diagnosis is made by a urologist that treats non-low-risk prostate cancer more likely to receive treatment vs. observation.

Contact: William B. Fitzgerald
WBFitzgerald@mdanderson.org
713-792-9518
The JAMA Network Journals

Public Release: 14-Jul-2014
Annals of Family Medicine
Bonuses for doctors do little to improve cancer screening in Ontario
Ontario spent nearly $110 million dollars between 2006 and 2010 on bonuses to motivate family doctors to screen more of their patients for cancer but these bonuses were associated with little or no improvement in actual cancer screening rates, according to researchers at St. Michael's Hospital and the Institute for Clinical Evaluative Sciences.

Contact: Geoff Koehler
koehlerg@smh.ca
416-864-6060 x6537
St. Michael's Hospital

Public Release: 14-Jul-2014
Cancer Cell
MD Anderson researchers discover new route for ovarian cancer spread
Circulating tumor cells spread ovarian cancer through the bloodstream, homing in on a sheath of abdominal fatty tissue where it can grow and metastasize to other organs, scientists at The University of Texas MD Anderson Cancer Center report in Cancer Cell.

Contact: Scott Merville
smerville@mdanderson.org
713-792-0661
University of Texas M. D. Anderson Cancer Center

Public Release: 14-Jul-2014
Cancer
Testicular cancer rates are on the rise in young Hispanic Americans
A new analysis has found that rates of testicular cancer have been rising dramatically in recent years among young Hispanic American men, but not among their non-Hispanic counterparts.

Contact: Evelyn Martinez
sciencenewsroom@wiley.com
Wiley

Public Release: 14-Jul-2014
Journal of Biological Chemistry
UEA research reveals how cannabis compound could slow tumour growth
Scientists at the University of East Anglia have shown how the main psychoactive ingredient in cannabis could reduce tumor growth in cancer patients. Research published today reveals the existence of previously unknown signaling platforms which are responsible for the drug's success in shrinking tumours. It is hoped that the findings could help develop a synthetic equivalent with anti-cancer properties.

Contact: Lisa Horton
l.horton@uea.ac.uk
44-016-035-92764
University of East Anglia

Public Release: 14-Jul-2014
Proceedings of the National Academy of Sciences
Capturing cancer: A powerful new technique for early diagnosis
In research appearing in today's issue of the journal Proceedings of the National Academy of Science, Stafford and his team describe an innovative technique for early disease detection, which they call immunosignaturing.

Contact: Joseph Caspermeyer
Joseph.Caspermeyer@asu.edu
Arizona State University

Public Release: 14-Jul-2014
JAMA Internal Medicine
Study finds diagnosing physicians influence therapy decisions for prostate cancer patients
New research from The University of Texas MD Anderson Cancer Center is shedding light on the important role a diagnosing urologist plays in whether older men with low-risk prostate cancer receive treatment for their disease, and if so, the type of treatment they receive as a result.

Contact: William Fitzgerald
wbfitzgerald@mdanderson.org
713-792-9518
University of Texas M. D. Anderson Cancer Center

Public Release: 14-Jul-2014
PLOS ONE
Scientists developed new technology for the diagnosis of cancer cells
The type of therapy a cancer patient receives, largely depends on the eye of a pathologist. However, human judgment is, by its very nature, subject to variation. To enhance the quality of diagnosis, scientists at Vetmeduni Vienna, the Medical University of Vienna and the Ludwig Boltzmann Institute for Cancer Research have developed a software that identifies cell structures and proteins in order to provide reliable diagnoses. The data was published in the journal PLOS ONE.

Contact: Lukas Kenner
lukas.kenner@meduniwien.ac.at
43-664-118-8385
University of Veterinary Medicine -- Vienna

Public Release: 14-Jul-2014
Biophysical Reviews and Letters
Cancer is avoidable as you grow older. Here's how.
Although it is widely thought that cancer is an inevitable consequence of aging, the risk of developing several common cancers decreases with age.

Contact: Jason Lim Chongjin
cjlim@wspc.com.sg
65-646-65775 x247
World Scientific

Public Release: 14-Jul-2014
Proceedings of the National Academy of Sciences
New combination drug controls tumor growth and metastasis in mice
Researchers at UC Davis, University of Massachusetts and Harvard Medical School have created a combination drug that controls both tumor growth and metastasis. By combining a COX-2 inhibitor, similar to Celebrex, and an epoxide hydrolase inhibitor, the drug controls angiogenesis, limiting a tumor's ability to grow and spread.
NIH/National Institute of Environmental Health Scien, Superfund, NIH/National Institute for Occupational Safety, Stop and Shop Pediatric Brain Tumor Fund, C.J. Buckley Pediatric Brain Tumor Fund, US Department of Veterans Affairs, American Asthma Society

Contact: Dorsey Griffith
dorsey.griffith@ucdmc.ucdavis.edu
916-734-9118
University of California - Davis Health System

Public Release: 13-Jul-2014
Nature
Antibody halts cancer-related wasting condition
Dana-Farber scientists pinpoint a molecular cause of cachexia, a wasting of fat and muscle occurring in half of all cancer patients, and identify a protein that when blocked might prevent the condition.
National Institutes of Health

Contact: Teresa Herbert
teresa_herbert@dfci.harvard.edu
617-632-5653
Dana-Farber Cancer Institute

Public Release: 13-Jul-2014
BioEssays
New theory turns cancer on its head
A new theory of how cancer works could lead to the next generation of treatments of the disease. The theory suggests that cancer forms when recently evolved genes are damaged, and cells have to revert to using older, inappropriate genetic pathways.

Contact: Dr Charley Lineweaver
charley.lineweaver@anu.edu.au
61-261-256-717
Australian National University

Public Release: 10-Jul-2014
International Journal of Clinical and Experimental Hypnosis
Men's hot flashes: Hypnotic relaxation may ease the discomfort men don't talk about
Men who experience hot flashes are unlikely to talk much about it, but they may find relief from their silent suffering if they are willing to try an unusual treatment, according to findings from a Baylor University case study.
National Institutes of Health

Contact: Terry Goodrich
terry_goodrich@baylor.edu
254-710-3321
Baylor University

Public Release: 10-Jul-2014
Biochemical Journal
Research reveals how key controller protein is switched on
New research has uncovered how a complex protein pivotal in the development of cancer, viral infection and autoimmune diseases is activated. The discovery answers a key question about one of the most widely-researched proteins in human biology, which has been the subject of tens of thousands of research papers and millions of pounds in research funding.
Wellcome Trust, Medical Research Council, AstraZeneca, Boehringer Ingelheim, and others

Contact: Alastair Stewart
alastair.stewart@biochemistry.org
44-207-685-2401
Biochemical Society

Public Release: 10-Jul-2014
Science
Cultured CTCs reveal genetic profile, potential drug susceptibility of breast cancer cells
A study in the July 11 issue of Science finds that circulating tumor cells captured with a microchip-based device developed at Massachusetts General Hospital can be cultured to establish cell lines for genetic analysis and drug testing and that those cell lines accurately reflect a tumor's genetic mutation over time and changing susceptibility to therapeutic drugs.
Johnson & Johnson, Stand Up to Cancer, Breast Cancer Research Foundation, National Institutes of Health, Howard Hughes Medical Institute

Contact: Katie Marquedant
kmarquedant@partners.org
617-726-0337
Massachusetts General Hospital

Public Release: 10-Jul-2014
Clinical Cancer Research
New drug active against most aggressive type of lung cancer cells
Scientists from the Cancer Research UK Manchester Institute, based at The University of Manchester and part of the Manchester Cancer Research Centre, teamed up with experts at AstraZeneca, as part of a collaboration agreed in 2010, to test a drug -- known as AZD3965 -- on small cell lung cancer cells.

Contact: Alison Barbuti
alison.barbuti@manchester.ac.uk
44-016-127-58383
University of Manchester

Public Release: 10-Jul-2014
Science
USC stem cell researcher targets the 'seeds' of breast cancer metastasis
For breast cancer patients, the era of personalized medicine may be just around the corner, thanks to recent advances by USC Stem Cell researcher Min Yu and scientists at Massachusetts General Hospital and Harvard Medical School. In a July 11 study in Science, Yu and her colleagues report how they isolated breast cancer cells circulating through the blood streams of six patients.
Breast Cancer Research Foundation, Stand Up to Cancer, Wellcome Trust, National Foundation for Cancer Research, National Institutes of Health, NIH/National Institute of Biomedical Imaging and Bioengineering, Susan G. Komen for the Cure K

Contact: Cristy Lytal
lytal@med.usc.edu
323-442-2172
University of Southern California - Health Sciences

Public Release: 10-Jul-2014
British Journal of Cancer
New therapeutic combination to slow resistant sarcomas
Researchers at sarcomas research group at the Bellvitge Biomedical Research Institute and the Catalan Institute of Oncology have been tested in 19 patients a new therapeutic combination to combat resistant sarcomas. The clinical trial results, which indicate that the new treatment could stabilize the growth of these tumors have been published this week in the British Journal of Cancer.

Contact: Arantxa Mena
amena@idibell.cat
34-932-607-282
IDIBELL-Bellvitge Biomedical Research Institute

Public Release: 9-Jul-2014
Journal of the American College of Surgeons
Fox Chase researchers recommend updating the staging criteria for breast cancer diagnoses
New findings from Fox Chase Cancer Center paint a relatively optimistic picture of women's chances of surviving a subset of breast cancers that have spread to the chest wall or skin, but not beyond.

Contact: Diana Quattrone
Diana.Quattrone@fccc.edu
215-728-7784
Fox Chase Cancer Center

Public Release: 9-Jul-2014
Nature
Protein pushes breast cancer cells to metastasize
Using an innovative tool that captures heretofore hidden ways that cells are regulated, scientists at Rockefeller University have identified a protein that makes breast cancer cells more likely to metastasize. What's more, the protein appears to trigger cancer's spread in part by blocking two other proteins that are normally linked to neurodegeneration, a finding that suggests these two disease processes could have unexpected ties.
National Institutes of Health, US Department of Defense

Contact: Franklin Hoke
fhoke@rockefeller.edu
212-327-8998
Rockefeller University

Public Release: 9-Jul-2014
Nature Communications
CNIO scientists discover that pluripotency factor NANOG is also active in adult organisms
Scientists from the Spanish National Cancer Research Center (CNIO) have discovered that NANOG, an essential gene for embryonic stem cells, also regulates cell division in stratified epithelia in adult organisms. According to the conclusions of the study, published in the journal Nature Communications, this factor could also play a role in the formation of tumors derived from stratified epithelia of the esophagus and skin.

Contact: Nuria Noriega
nnoriega@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)

Public Release: 9-Jul-2014
New England Journal of Medicine
How antioxidants can accelerate cancers, and why they don't protect against them
Two distinguished cancer researchers have proposed why antioxidant supplements might not be working to reduce cancer development, and why they may actually do more harm than good.
Lustgarden Pancreatic Cancer Foundation

Contact: Peter Tarr
tarr@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory

Public Release: 9-Jul-2014
Journal of Clinical Oncology
Depressed men with prostate cancer are diagnosed later stage, get less effective therapies
Depressed men with localized prostate cancer were more likely to be diagnosed with more aggressive prostate cancer, received less effective treatments and survived for shorter times than prostate cancer patients who were not depressed, a UCLA study has found.
Department of Defense Physician Training Award

Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-794-2262
University of California - Los Angeles Health Sciences

Public Release: 9-Jul-2014
Journal of Clinical Oncology
Vasectomy may increase risk of aggressive prostate cancer
Vasectomy was associated with a small increased risk of prostate cancer, and a stronger risk for advanced or lethal prostate cancer according to a new study from Harvard School of Public Health.
NIH/National Cancer Institute

Contact: Todd Datz
tdatz@hsph.harvard.edu
617-432-8413
Harvard School of Public Health

Showing releases 1101-1125 out of 1245.

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