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Showing releases 1126-1150 out of 1339.

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Public Release: 31-Dec-2014
Journal of Clinical Oncology
Stereotactic body radiation therapy plus chemotherapy improves survival among stage 4 lung cancer patients
A clinical trial that combined stereotactic body radiation therapy with a specific chemotherapy regimen more than doubled survival rates for certain stage 4 lung cancer patients.

Contact: Lori Sundeen Soderbergh
lori.soderbergh@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center

Public Release: 31-Dec-2014
Cell
3-D culture system for pancreatic cancer has potential to change therapeutic approaches
Pancreatic cancer is one of the most deadly forms of cancer, with only 6 percent of patients surviving five years after diagnosis. Today, CSHL and The Lustgarten Foundation announce the development of a new model system to grow both normal and cancerous pancreatic cells in the laboratory. Their work promises to change the way pancreatic cancer research is done, allowing scientists to interrogate the pathways driving this devastating disease while searching for new drug targets.
Lustgarten Foundation for Pancreatic Cancer Research, Cold Spring Harbor Laboratory Association, NIH/National Cancer Institute Center for Cancer Genomics, Carcinoid Foundation, PCUK, David Rubinstein Center for Pancreatic Cancer Research

Contact: Jaclyn Jansen
jjansen@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory

Public Release: 31-Dec-2014
New England Journal of Medicine
Mayo Clinic: Women with atypical hyperplasia are at higher risk of breast cancer
Women with atypical hyperplasia of the breast have a higher risk of developing breast cancer than previously thought, a Mayo Clinic study has found. Results of the study appear in a special report on breast cancer in the New England Journal of Medicine.
National Institutes of Health

Contact: Joe Dangor
newsbureau@mayo.edu
507-284-5005
Mayo Clinic

Public Release: 31-Dec-2014
CA: A Cancer Journal for Clinicians
More than 1.5 million cancer deaths averted during 2 decades of dropping mortality
The American Cancer Society's annual cancer statistics report finds that a 22 percent drop in cancer mortality over two decades led to the avoidance of more than 1.5 million cancer deaths that would have occurred if peak rates had persisted.
American Cancer Society

Contact: David Sampson
david.sampson@cancer.org
American Cancer Society

Public Release: 30-Dec-2014
PLOS Medicine
Neonatal HBV vaccine reduces liver cancer risk
Neonatal HBV vaccination reduces the risk of liver cancer and other liver diseases in young adults in China, according to a study published by Chunfeng Qu, Taoyang Chen, Yawei Zhang and colleagues from the Cancer Institute & Hospital at the Chinese Academy of Medical Sciences, Qidong Liver Cancer Institute, China, and Yale School of Public Health and School of Medicine, USA in this week's PLOS Medicine.
State Key Projects Specialized on Infection Diseases, 973 Program Project of China, National Institutes of Health, 6th to 11th Key Technologies R&D Program of China

Contact: Maya Sandler
medicinepress@plos.org
PLOS

Public Release: 30-Dec-2014
Proceedings of the National Academy of Sciences
Cancer treatment potential discovered in gene repair mechanism
Case Western Reserve researchers have identified a two-pronged therapeutic approach that shows great potential for weakening and then defeating cancer cells. The team's complex mix of genetic and biochemical experiments unearthed a way to increase the presence of a tumor-suppressing protein which, in turn, gives it the strength to direct cancer cells toward a path that leads to their destruction. The breakthrough detailed appeared in the Nov. 24 online edition of the journal PNAS.
National Institutes of Health, National Center for Advancing Translational Sciences, Clinical and Translational Collaborative of Cleveland

Contact: Jeannette Spalding
jeannette.spalding@case.edu
216-368-3004
Case Western Reserve University

Public Release: 30-Dec-2014
American Journal of Roentgenology
Lung cancer metastases may travel through airways to adjacent or distant lung tissue
A new study by researchers in Canada supports the hypothesis that lung cancer, particularly adenocarcinoma, may spread through the airways. The putative occurrence of intrapulmonary aerogenous metastasis of lung cancer has staging, management, and prognostic implications.

Contact: Lissa D. Hurwitz
lhurwitz@arrs.org
703-858-4332
American Roentgen Ray Society

Public Release: 29-Dec-2014
Protein ID'd as possible universal therapeutic target for many infections, including Ebola
A protein called GRP78 could be a universal therapeutic target for treating human diseases like brain cancer, Ebola, influenza, hepatitis and superbug bacteria such as methicillin-resistant Staphylococcus epidermidis and methicillin-resistant Staphylococcus aureus, according to a Virginia Commonwealth University-led preclinical study published this month in the Journal of Cellular Physiology.
National Institutes of Health, Virginia Commonwealth University

Contact: Brian McNeill
bwmcneill@vcu.edu
804-938-7558
Virginia Commonwealth University

Public Release: 29-Dec-2014
Stem Cells
Reprogramming stem cells may prevent cancer after radiation
University of Colorado Cancer Center study published today in Stem Cells shows that pre-programmed stem cell death allows cancer to grow after full-body irradiation, and that NOTCH signaling may restore stem cell function, protecting against cancer after radiation.
National Institutes of Health, Leukemia and Lymphoma Society

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 29-Dec-2014
Proceedings of the National Academy of Sciences
Sugar molecule links red meat consumption and elevated cancer risk in mice
While people who eat a lot of red meat are known to be at higher risk for certain cancers, other carnivores are not, prompting researchers at the University of California, San Diego School of Medicine to investigate the possible tumor-forming role of a sugar called Neu5Gc, which is naturally found in most mammals but not in humans.
Ellison Medical Foundation, NIH/National Cancer Institute, Samuel and Ruth Engelberg Fellowship from the Cancer Research Institute, Swiss National Science Foundation

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 29-Dec-2014
Cancer Discovery
Cancer-causing mutation discovered in 1982 finally target of clinical trials
A recent article in the journal Cancer Discovery describes clinical trials at the University of Colorado Cancer Center and elsewhere that match drugs to long-overlooked oncogene, TRK, offering targeted treatment options for cancers that harbor these gene abnormalities.
V Foundation, National Institutes of Health, National Cancer Institute

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 29-Dec-2014
Proceedings of the National Academy of Sciences
Tracing evolution of chicken flu virus yields insight into origins of deadly H7N9 strain
An international research team has shown how changes in a flu virus that has plagued Chinese poultry farms for decades helped create the novel avian H7N9 influenza A virus that has sickened more than 375 people since 2013. The research appears in the current online early edition of the scientific journal Proceedings of the National Academy of Sciences.
National Natural Science Foundation of China, National Basic Research Program, China Scholarship Foundation, Key Technologies Research & Development Program of China, China Agriculture Research System, NIH/National Institute of Allergy and Infectious Dise

Contact: Carrie Strehlau
carrie.strehlau@stjude.org
901-595-2295
St. Jude Children's Research Hospital

Public Release: 29-Dec-2014
Plastic and Reconstructive Surgery
Breast reconstruction using patient's own tissues yield higher satisfaction rates
For women who have undergone mastectomy, breast reconstruction using the patient's own tissues -- rather than implants -- provides higher satisfaction scores, reports a study in the January issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

Contact: Connie Hughes
Connie.Hughes@wolterskluwer.com
646-674-6348
Wolters Kluwer Health

Public Release: 24-Dec-2014
Cell Reports
Scientists zero in on how lung cancer spreads
Cancer Research UK scientists have taken microscopic images revealing that the protein ties tethering cells together are severed in lung cancer cells.

Contact: Emily Head
press.office@cancer.org.uk
020-346-96189
Cancer Research UK

Public Release: 24-Dec-2014
Nature Communications
Scientists identify rare cancer's genetic pathway
An international research team, including four Simon Fraser University scientists, has identified the 'mutational landscape' of intrahepatic cholangiocarcinoma, a rare, highly fatal form of liver cancer that disproportionately affects people in Asian countries.
Natural Sciences and Engineering Research Council

Contact: Jack Chen
chenn@sfu.ca
604-368-5049
Simon Fraser University

Public Release: 23-Dec-2014
JAMA Dermatology
Trends in indoor tanning among us high school students
While indoor tanning has decreased among high school students, about 20 percent of females engaged in indoor tanning at least once during 2013 and about 10 percent of girls frequently engaged in the practice by using an indoor tanning device 10 or more times during the year, according to a research letter published online by JAMA Dermatology.

Contact: Brittany Behm
media@cdc.gov
404-639-3286
The JAMA Network Journals

Public Release: 23-Dec-2014
PLOS Biology
CNIO researchers activate hair growth by modifying immune cells
How to restore hair loss is a task not undertaken exclusively by beauty practitioners. The discovery, now published by a group from the Spanish National Cancer Research Centre, reveals a novel angle to spur hair follicle growth. This also adds new knowledge to a broader problem: how to regenerate tissues in an adult organism, especially the skin.

Contact: Nuria Noriega
nnoriega@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)

Public Release: 23-Dec-2014
Clinical Cancer Research
Armed virus shows promise as treatment for pancreatic cancer
A new combination of two different approaches -- virotherapy and immunotherapy -- is showing 'great promise' as a treatment for pancreatic cancer, according to new research from Queen Mary University of London.
Pancreatic Cancer Research Fund

Contact: Maggie Blanks
maggieblanks@pcrf.org.uk
44-020-836-01119
Pancreatic Cancer Research Fund

Public Release: 23-Dec-2014
EBioMedicine
Researchers confirm whole-genome sequencing can successfully identify cancer-related mutations
UT Southwestern Medical Center cancer researchers have demonstrated that whole-genome sequencing can be used to identify patients' risk for hereditary cancer.

Contact: Lori Sundeen Soderbergh
lori.soderbergh@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center

Public Release: 23-Dec-2014
Science Signaling
Researchers map paths to cancer drug resistance
A team of researchers led by Duke Cancer Institute has identified key events that prompt certain cancer cells to develop resistance to otherwise lethal therapies.
National Institutes of Health

Contact: Sarah Avery
sarah.avery@duke.edu
919-660-1306
Duke University Medical Center

Public Release: 22-Dec-2014
Neurosurgery
Limit imaging scans for headache? Neurosurgeons raise concerns
Recent guidelines seeking to reduce the use of neuroimaging tests for patients with headaches run the risk of missing or delaying the diagnosis of brain tumors, according to a special article in the January issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

Contact: Connie Hughes
Connie.Hughes@wolterskluwer.com
646-674-6348
Wolters Kluwer Health

Public Release: 22-Dec-2014
Cancer Research
Suppressing a protein reduces cancer spread in mice
In a new study, researchers found that a specific protein called 'chitinase 3-like-1' appears key in enabling malignant melanoma or breast cancer to spread to the lungs of mice. Decreasing its levels or blocking the protein dramatically reduced that spread.
National Institutes of Health

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University

Public Release: 22-Dec-2014
PLOS ONE
University of Louisville faculty discover mutation role involved in 75 percent of glioblastomas, melanomas
Researchers at the University of Louisville's James Graham Brown Cancer Center have identified for the first time mutations that destabilize a DNA structure that turns a gene off. These mutations occur at four specific sites in what is known as the 'hTERT promoter' in more than 75 percent of glioblastomas and melanomas.

Contact: Jill Scoggins
jill.scoggins@louisville.edu
502-852-7461
University of Louisville

Public Release: 22-Dec-2014
Biophysical Journal
Penn researchers model the mechanics of cells' long-range communication
Interdisciplinary research at the University of Pennsylvania is showing how cells interact over long distances within fibrous tissue, like that associated with many diseases of the liver, lungs and other organs.
National Institutes of Health, National Science Foundation

Contact: Evan Lerner
elerner@upenn.edu
215-573-6604
University of Pennsylvania

Public Release: 22-Dec-2014
Journal of Clinical Oncology
Risk for leukemia after treatment for early-stage breast cancer higher than reported
The risk of developing leukemia after radiation therapy or chemotherapy for early stage breast cancer remains very small, but it is twice as high as previously reported, according to results of a new study led by researchers at the Johns Hopkins Kimmel Cancer Center.
NIH/National Cancer Institute, Susan G. Komen for the Cure

Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medicine

Showing releases 1126-1150 out of 1339.

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