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Showing releases 1151-1175 out of 1252.

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Public Release: 12-Jun-2015
Mini-breast grown in Petri dishes -- a new tool for cancer research
About 70,000 Women are diagnosed with breast cancer every year in Germany alone. Despite significant progress in the treatment of common types of breast cancer, some aggressive subtypes are poorly understood and remain incurable. A new experimental model opens new avenues for mammary gland biology and basic breast cancer research. Researchers at the Helmholtz Center in Munich are now able to create three-dimensional organoid-structures that recapitulate normal breast development and function from single patient-derived cells.
Max Eder Grant of the German Cancer Aid Foundation

Contact: Dr. Christina Scheel
Helmholtz Zentrum München - German Research Center for Environmental Health

Public Release: 11-Jun-2015
New drug triggers tissue regeneration: Faster regrowth and healing of damaged tissues
The concept sounds like the stuff of science fiction: take a pill, and new tissues grow to replace damaged ones. Case Western Reserve and University of Texas-Southwestern researchers announce steps toward turning this idea into reality. In a study published in Science June 12, they detail how a new drug repaired damage to the colon, liver and bone marrow in animal models -- even saving mice who would have died in a bone marrow transplantation model.
National Institutes of Health, Cleveland Clinic/National Center for Accelerating Innovation, Marguerite Wilson Foundation, Welch Foundation, Cancer Prevention & Research Institute of Texas, Korean National Research Foundation

Contact: Jeannette Spalding
Case Western Reserve University

Public Release: 11-Jun-2015
Cancer Discovery
MD Anderson study finds gene mutations sensitize tumors to specific cancer drugs
Mutations in ARID1a, which are common in many cancer types, disrupt DNA damage repair in cancer cells, allowing the cancer to progress.

Contact: Clayton R. Boldt
University of Texas M. D. Anderson Cancer Center

Public Release: 11-Jun-2015
JAMA Oncology
Obesity associated with increased breast cancer risk in postmenopausal women
An analysis of extended follow-up data from the Women's Health Initiative clinical trials suggests that postmenopausal women who were overweight and obese had an increased risk of invasive breast cancer compared to women of normal weight, according to an article published online by JAMA Oncology.

Contact: Kristen Lidke Woodward
The JAMA Network Journals

Public Release: 11-Jun-2015
International Journal of Epidemiology
Nuts and peanuts may protect against major causes of death
A paper published today in the International Journal of Epidemiology confirms a link between peanut and nut intake and lower mortality rates, but finds no protective effect for peanut butter. Men and women who eat at least 10 grams of nuts or peanuts per day have a lower risk of dying from several major causes of death than people who don't consume nuts or peanuts.

Contact: Chloe Foster
Oxford University Press

Public Release: 11-Jun-2015
American Journal of Public Health
Probing ways to convince young women not to use indoor tanning
Messages with images depicting the harsh realities of melanoma are more powerful than the text-only warning required by the US Food and Drug Administration in persuading women to reconsider indoor tanning.
Harry J. Lloyd Charitable Trust

Contact: Todd Bentsen
Georgetown University Medical Center

Public Release: 11-Jun-2015
Cell Reports
Scientists find way to disrupt brain tumor stem cells
Brain tumor stem cells can resist treatment and regrow tumors, but scientists have identified a vulnerability in these cells that could lead to a new approach in battling deadly brain tumors.

Contact: Michael C. Purdy
Washington University School of Medicine

Public Release: 11-Jun-2015
Cancer Epidemiology, Biomarkers & Prevention
Comorbid conditions associated with worse lung cancer survival
Lung cancer patients with comorbid conditions such as chronic obstructive pulmonary disease, diabetes, or congestive heart failure had a higher risk of death than lung cancer patients without comorbid conditions.
Patient-Centered Outcomes Research Institute, Veterans Health Administration, Nebraska Department of Health and Human Services, UNMC College of Public Health, National Science Foundation, CDC Public Health Infrastructure

Contact: Lauren Riley
American Association for Cancer Research

Public Release: 11-Jun-2015
WCMC researchers discover how ovarian cancer halts body's natural defense against tumor
Ovarian cancer shuts down immune system cells that would otherwise act as a first line of defense against the deadly tumor, Weill Cornell Medical College scientists report today. But a therapy that restores the cells' disease-fighting abilities could provide a powerful new strategy to attack the cancer, which kills more than 14,000 women each year.
National Institutes of Health, Irvington Institute Fellowship Program of the Cancer Research Institute, Fundación Alfonso Martín Escudero

Contact: Jen Gundersen
Weill Cornell Medical College

Public Release: 11-Jun-2015
Gynecologic Oncology
Nearly 10 percent of women live too far from access to gynecologic cancer care
More than one-third of counties in the Unites States are located more than 50 miles from the nearest gynecologic oncologist, making access to specialty care for ovarian and other gynecologic cancers difficult for nearly 15 million women.

Contact: Katie Delach
University of Pennsylvania School of Medicine

Public Release: 11-Jun-2015
Nature Immunology
Call for help to killer cells improves cancer rejection
Many tumors are infiltrated by cells of the innate immune system called eosinophils. Immunologists from the German Cancer Research Center are now the first to show that eosinophils do, in fact, improve the body's defense against cancer. By releasing special agents, they attract killer T cells into cancerous tissue; the T cells then attack the cancer cells. This finding may help develop more effective cancer immunotherapies.

Contact: Dr. Sibyle Kohlstädt
German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)

Public Release: 11-Jun-2015
European Conferences on Biomedical Optics 2015
Journal of Biomedical Optics
'Light for Life' section marks Year of Light, parallels Biomedical Optics conference
A special section published this month in the Journal of Biomedical Optics titled 'Light for Life' celebrates the International Year of Light and parallels a dedicated session at the European Conference of Biomedical Optics, set for June 21-25, in Munich. The journal is published by SPIE, the international society for optics and photonics, a sponsor of the conference.

Contact: Amy Nelson
SPIE--International Society for Optics and Photonics

Public Release: 11-Jun-2015
Laboratory Investigation
Lab study: Daily aspirin could block growth of breast, other cancers
A Veterans Affairs lab study found that a daily dose of aspirin was effective at blocking breast tumor growth. Previous studies have already shown a similar effect on colon, gastrointestinal, prostate, and other cancers.
Department of Veterans Affairs

Contact: Joseph L. Burks
Veterans Affairs Research Communications

Public Release: 11-Jun-2015
ADAMTS family of genes may be the next 'thing' in ovarian cancer treatment
There is the Addams Family. And then there is the ADAMTS family. While one is mindless entertainment, the latter may prove to be a new genetic avenue for designing ovarian cancer treatment.

Contact: Ron Gilmore
University of Texas M. D. Anderson Cancer Center

Public Release: 10-Jun-2015
ACS Nano
Nanoparticles target and kill cancer stem cells that drive tumor growth
Many cancer patients survive treatment only to have a recurrence within a few years. Recurrences and tumor spreading are likely due to cancer stem cells that can be tough to kill with conventional cancer drugs. But now researchers have designed nanoparticles that specifically target these hardy cells to deliver a drug. The nanoparticle treatment, reported in the journal ACS Nano, worked far better than the drug alone in mice.

Contact: Michael Bernstein
American Chemical Society

Public Release: 10-Jun-2015
Annals of Thoracic Surgery
Multimodality treatment for metastatic lung cancer with surgery may improve survival rates
Patients diagnosed with an advanced form of metastatic non-small cell lung cancer may benefit from surgical resection (removal of all or part of the lung) in combination with chemotherapy and radiation therapy, according to an article in the June 2015 issue of The Annals of Thoracic Surgery.

Contact: Cassie McNulty

Public Release: 10-Jun-2015
Science Translational Medicine
'Mutation accelerator' identified in gene mutation linked to common adult leukemia
In preliminary experiments with mice and lab-grown cells, Johns Hopkins Kimmel Cancer Center scientists have found that a protein-signaling process accelerates the work of the gene most frequently mutated in a common form of adult leukemia and is likely necessary to bring about the full-blown disease.
National Institutes of Health, Leukemia and Lymphoma Society, Gabrielle's Angel Foundation for Cancer Research, Edward P. Evans Foundation, Petre Foundation

Contact: Vanessa Wasta
Johns Hopkins Medicine

Public Release: 10-Jun-2015
1st UK Brain Tumour Research Workshop
Plymouth University researchers in first ever UK brain tumor workshop
Organized by charity Brain Tumour Research, scientists from Plymouth University joined colleagues from other brain tumor research institutions for the first ever UK brain tumor research workshop.

Contact: Andrew Gould
University of Plymouth

Public Release: 10-Jun-2015
2015 AAPS National Biotechnology Conference
Cutting-edge research unveiled at 2015 AAPS National Biotechnology Conference
Innovative vaccine and tumor research will be unveiled at the American Association of Pharmaceutical Scientists' National Biotechnology Conference. The meeting takes place Monday, June 8-10 at the San Francisco Marriott Marquis.

Contact: Stacey May
American Association of Pharmaceutical Scientists

Public Release: 10-Jun-2015
Lancet Oncology
Survival benefit with 'fully human' EGFR antibody necitumumab in squamous NSCLC
This week, Lancet Oncology reports results of a 1,093-person phase III clinical trial of the drug Necitumumab (IMC-11F8) combined with chemotherapies gemcitabine and cisplatin against stage IV squamous non-small cell lung cancer. With addition of necitumumab, median overall survival was 11.5 months compared with median survival of 9.9 months with the two chemotherapies alone.

Contact: Garth Sundem
University of Colorado Anschutz Medical Campus

Public Release: 10-Jun-2015
Researchers develop novel ketone supplements to enhance non-toxic cancer therapy
A team of researchers from the Hyperbaric Biomedical Research Laboratory at the University of South Florida (Tampa, Fla.) doubled survival time in an aggressive metastatic cancer model using a novel combination of non-toxic dietary and hyperbaric oxygen therapies.
Scivation Inc.

Contact: Anne DeLotto Baier
University of South Florida (USF Health)

Public Release: 10-Jun-2015
'Chromosome shattering' seen in plants, cancer
Plants can undergo the same extreme 'chromosome shattering' seen in some human cancers and developmental syndromes, UC Davis researchers have found. Chromosome shattering, or 'chromothripsis,' has until now only been seen in animal cells.
HHMI, Gordon and Betty Moore Foundation

Contact: Andy Fell
University of California - Davis

Public Release: 10-Jun-2015
New England Journal of Medicine
Study discovers new method of classifying low-grade brain tumors
Scientists and physicians from federally designated cancer centers used molecular and genetic analysis to develop a new method of classifying brain tumors known as low and intermediate grade gliomas. The approach reduces the role of individual observers' assessments of the tumors' appearance. This should improve diagnosis and treatment, and identifies biological targets for future therapies.
National Institutes of Health

Contact: George Stamatis
University Hospitals Case Medical Center

Public Release: 10-Jun-2015
SLEEP 2015
Sleep duration and quality may impact cancer survival rate
A new study suggests that pre-diagnostic short sleep duration and frequent snoring were associated with significantly poorer cancer-specific survival, particularly among women with breast cancer.

Contact: Lynn Celmer
American Academy of Sleep Medicine

Public Release: 10-Jun-2015
New England Journal of Medicine
Multi-center study redefines brain tumor diagnosis and treatment
Not all brain cancers are the same but together they represent a deadly disease that has been difficult to identify and treat. Scientists at multiple institutions have found a new way of classifying brain cancers that could very well change how the illness is diagnosed and treated.

Contact: Ron Gilmore
University of Texas M. D. Anderson Cancer Center

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