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Showing releases 1151-1175 out of 1310.

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Public Release: 19-Nov-2015
Seminars in Cancer Biology
UAEU researchers as part of a global task force re-address untreatable cancers & disease relapse
UAEU scientists in collaboration with colleagues from top tier institutions such as Harvard, MIT, Berkeley, Stanford and John Hopkins were put together by a Canadian NGO called 'Getting to Know Cancer'. Interdisciplinary teams nominated a series of high-priority molecular targets that could be reached with chemicals to improve patient outcomes in most cancers. Candidates for mixtures of natural-based chemicals with potential to reach a broad-spectrum of priority targets in most cancer types were recommended.

Contact: Amr A. Amin
United Arab Emirates University

Public Release: 19-Nov-2015
Cancer Epidemiology, Biomarkers & Prevention
Possible new mechanism for aspirin's role in cancer prevention
In a study published in the journal of Cancer Epidemiology, Biomarkers, and Prevention, Cornelia Ulrich from Huntsman Cancer Institute and her collaborators used a new technique, metabolite profiling, to identify a biochemical pathway previously unknown to be regulated by aspirin. Specifically, the researchers found that aspirin substantially decreases the level of a chemical called 2-hydroxyglutarate in the blood of healthy volunteers and in two colorectal cancer cell lines.
National Institutes of Health, Huntsman Cancer Foundation, German Cancer Research Center

Contact: Linda Aagard
University of Utah Health Sciences

Public Release: 19-Nov-2015
Cancer Cell
Researchers develop model to study, find ways to target rare tumor
Cancer researchers at the University of Cincinnati (UC) have found a new target that could lead to therapies for a rare type of tumor. These findings are being reported in the Nov. 9 advance online edition of the journal Cancer Cell.
National Institutes of Health

Contact: Katie Pence
University of Cincinnati Academic Health Center

Public Release: 19-Nov-2015
Journal of Controlled Release
Nanocarriers may carry new hope for brain cancer therapy
Berkeley Lab researchers have developed a new family of nanocarriers, called '3HM,' that meets all the size and stability requirements for effectively delivering therapeutic drugs to the brain for the treatment of a deadly form of cancer known as glioblastoma multiforme.
National Institutes of Health

Contact: Lynn Yarris
DOE/Lawrence Berkeley National Laboratory

Public Release: 19-Nov-2015
Sensory illusion causes cells to self-destruct
UCSF researchers has discovered that even brainless single-celled yeast have sensory biases that can be hacked by a carefully engineered illusion, a finding that could be used to develop new approaches to fighting diseases such as cancer.

Contact: Nicholas Weiler
University of California - San Francisco

Public Release: 19-Nov-2015
JAMA Oncology
Studies examine long-term outcomes in childhood, young adult cancer survivors
JAMA Oncology published two studies and a related editorial focused on long-term outcomes in survivors of childhood or young adult cancer.

Contact: Kathrine Rugbjerg
The JAMA Network Journals

Public Release: 19-Nov-2015
Applied Catalysis B Environmental
Better catalysts will remove carcinogenic chlorine compounds from water
The Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw has just unveiled two new catalysts developed in close cooperation with the Jagiellonian University in Cracow and the Jan Kochanowski University in Kielce. The catalysts have been designed with the effective treatment of tap water in mind, eliminating harmful chlorine compounds.

Contact: Dr. Anna Srebowata
Institute of Physical Chemistry of the Polish Academy of Sciences

Public Release: 19-Nov-2015
Cell Reports
UTSW research finding could lead to targeted therapies for inflammatory bowel diseases
UT Southwestern Medical Center researchers have shown that a pathogen-sensing molecule plays a vital role in keeping gastrointestinal systems healthy.
Crohn's and Colitis Foundation, American Cancer Society

Contact: Debbie Bolles
UT Southwestern Medical Center

Public Release: 19-Nov-2015
Women's Health Issues
Study: Risk of undetected cancer in gynecologic surgery higher than previously thought
A Boston Medical Center study revealed that 1 in 352 women had an unsuspected cancer at the time of gynecologic surgery for disease that was thought to be benign. The study is published online in advance of print in the journal Women's Health Issues.
American Cancer Society

Contact: Elissa Snook
Boston University Medical Center

Public Release: 19-Nov-2015
Cancer Research
Scientists find way to make resistant brain cancer cells sensitive to treatment
Robert Gourdie and his research team developed a peptide called aCT1 (pronounced act one) to inhibit connexin 43-caused overactivity. The result was damaged tissue healed more quickly, with lower amounts of inflammation and scarring.

Contact: Paula Byron
Virginia Tech

Public Release: 19-Nov-2015
Intelligent gel attacks cancer
A new injectable 'biogel' is effective in delivering anti-cancer agents directly into cancerous tumors and killing them. This technology, developed by researchers at the University of Montreal Hospital Research Centre, has already been successfully tested in the laboratory. If it works in patients, the therapy could one day revolutionize treatment for many forms of cancer.

Contact: Isabelle Girard
University of Montreal Hospital Research Centre (CRCHUM)

Public Release: 18-Nov-2015
Seminars in Cancer Biology
Global task force tackles problem of untreatable cancers and disease relapse 
Combinations of a significant number of non-toxic substances, many of which can be found in plants and foods, may give us a chance to stop untreatable cancers and prevent disease.

Contact: Leroy Lowe
Saarland University

Public Release: 18-Nov-2015
Scientific Reports
Technique to more effectively diagnose and treat cancer developed by Georgia State University
A method to better trace changes in cancers and treatment of the prostate and lung without the limitations associated with radiation has been developed by Georgia State University researchers.

Contact: Brian Mullen
Georgia State University

Public Release: 18-Nov-2015
One very brainy bird
A joint study by the University of Iowa and University of California-Davis found pigeons performed as well as humans in categorizing digitized slides and mammograms of benign and malignant human breast tissue. Results published in the journal PLOS ONE.
National Institutes of Health

Contact: Richard Lewis
University of Iowa

Public Release: 18-Nov-2015
Science Translational Medicine
Wisconsin scientists grow functional vocal cord tissue in the lab
University of Wisconsin-Madison scientists have succeeded in growing functional vocal cord tissue in the laboratory, a major step toward restoring a voice to people who have lost their vocal cords to cancer surgery or other injuries. Dr. Nathan Welham, a UW speech-language pathologist, and colleagues from several disciplines were able to bioengineer vocal cord tissue able to transmit sound, they reported in a study published today in the journal Science Translational Medicine.
NIH/National Institute on Deafness and Other Communication Disorders, NIH/National Institute of Allergy and Infectious Diseases

Contact: Susan Lampert Smith
University of Wisconsin-Madison

Public Release: 18-Nov-2015
Lancet Haematology
Late effects of treatment study continues sustained academic effort in Hodgkin's lymphoma
'These study results are exciting. They should allow physicians to optimize the combination of systemic therapy and radiation and thereby balance the risks and benefits of different regimens in individual patients.'

Contact: John Bean
European Organisation for Research and Treatment of Cancer

Public Release: 18-Nov-2015
Cancer Epidemiology, Biomarkers & Prevention
Higher nicotine, carcinogen levels among smokeless tobacco users compared with cig users
U.S. adults who used only smokeless tobacco products had higher levels of biomarkers of exposure to nicotine and a cancer-causing toxicant -- the tobacco-specific nitrosamine NNK -- compared with those who used only cigarettes.
U.S. Food and Drug Administration, Centers for Disease Control and Prevention

Contact: Lauren Riley
American Association for Cancer Research

Public Release: 18-Nov-2015
Clinical Cancer Research
Investigational immunotherapeutic increased bladder cancer survival
Among patients with metastatic bladder cancer that had progressed after platinum-based chemotherapy, those who received an investigational, personalized peptide cancer vaccine and best-supportive care had extended overall survival compared with those who received best-supportive care alone, according to results from a randomized, phase II clinical.
Ministry of Education, Science, Sports, and Culture in Japan

Contact: Lauren Riley
American Association for Cancer Research

Public Release: 18-Nov-2015
Biotechnology Journal
Chemical engineers have figured out how to make vaccines faster
Researchers at Brigham Young University have devised a system to speed up the process of making life-saving vaccines for new viruses. Their concept is to create the biological machinery for vaccine production en masse, put it in a freeze-dried state and stockpile it around the country. Then, when a new virus hits, labs can simply add water to a 'kit' to rapidly produce vaccines.
National Science Foundation, Defense Advanced Research Projects Agency

Contact: Todd Hollingshead
Brigham Young University

Public Release: 18-Nov-2015
Proceedings of the National Academy of Sciences
Mutations in key cancer protein suggest new route to treatments
Researchers found they could disrupt STAT3's ability to act as a transcription factor by altering part of the protein, which interfered with its cancer-promoting activity. The findings suggest a basis for new, targeted approaches to fighting cancer.

Contact: Katherine Fenz
Rockefeller University

Public Release: 18-Nov-2015
Current Biology
Marine animals use new form of secret light communication
Researchers from the Queensland Brain Institute at The University of Queensland have uncovered a new form of secret light communication used by marine animals. The findings may have applications in satellite remote sensing, biomedical imaging, cancer detection, and computer data storage.
Air Force Office of Scientific Research, Asian Office of Aerospace Research and Development, Australian Research Council

Contact: Bernadette Condren
University of Queensland

Public Release: 18-Nov-2015
International Society of Neurogastronomy Symposium
Neurogastronomy: How our brains perceive the flavor of food
Neuroscientists, food scientists and internationally renowned chefs convened at the University of Kentucky recently to explore ways to help patients with neurologically related taste impairments enjoy food again.

Contact: Laura Dawahare
University of Kentucky

Public Release: 18-Nov-2015
Breast Cancer Research and Treatment
Without prescription coverage, some cancer patients do without even low-cost drugs
A University of Colorado Cancer Center study published in the journal Breast Cancer Research and Treatment shows that breast cancer patients whose health insurance plans included prescription drug benefits were 10 percent more likely to start important hormonal therapy than patients who did not have prescription drug coverage. Women with household income below $40,000 were less than half as likely as women with annual household income greater than $70,000 to continue hormonal therapy.
National Institutes of Health, NIH/National Cancer Institute

Contact: Garth Sundem
University of Colorado Anschutz Medical Campus

Public Release: 18-Nov-2015
Seminars in Cancer Biology
Plant and food-based compounds may be key to future cancer prevention
Rather than targeting one or two specific genes or proteins that contribute to cancer, the task force was charged with researching a broad-spectrum approach. 'This type of approach involves combinations of multiple low-toxicity agents that can collectively impact many pathways that are known to be important for the genesis and spread of cancer,' said Kumar.
Getting to Know Cancer

Contact: Steven Blanchard
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 18-Nov-2015
New England Journal of Medicine
Why do children develop cancer?
As new scientific discoveries deepen our understanding of how cancer develops in children, doctors and other healthcare providers face challenges in better using that knowledge to guide treatment and counsel families and patients. A CHOP pediatric oncologist offers expert commentary on a major study of cancer predisposition genes in children being published today, and outlines areas for further investigation.

Contact: John Ascenzi
Children's Hospital of Philadelphia

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