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Showing releases 1151-1175 out of 1216. << < 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 > >>
Public Release: 12-Feb-2013
Opioid prescription is on the increase More and more opioids are being prescribed for pain relief in Germany. This is the conclusion arrived at by Ingrid Schubert, Peter Ihle, and Rainer Sabatowski, whose study of a sample of inhabitants of the state of Hesse with health insurance from a large statutory provider is published in the latest issue of Deutsches Ärzteblatt International. Contact: Dr. rer. soc. Ingrid Schubert Public Release: 12-Feb-2013
Study identifies factors associated with eradication of bacteria linked to gastric cancer In an analysis of the results of interventions to eradicate the bacterium Helicobacter pylori (a risk factor for gastric cancer) in seven diverse community populations in Latin America, researchers found that geographic site, demographic factors, adherence to initial therapy and infection recurrence may be as important as the choice of antibiotic regimen in H pylori eradication interventions, according to a study appearing in the Feb. 13 issue of JAMA. Contact: Craig Boerner Public Release: 12-Feb-2013
Consumers have few negative reactions to the results of genetic testing for cancer mutations A 23andMe study of consumers' reactions to genetic testing found that even when the tests revealed high-risk mutations in individuals, those individuals had few negative reactions to the news. Instead of inducing serious anxiety, the test results prompted people to take positive steps, including follow-up visits with a doctor and discussions with family members who could also be at risk. Contact: Catherine Afarian Public Release: 12-Feb-2013
Lung cancer set to overtake breast cancer as the main cause of cancer deaths among European women Lung cancer is likely to overtake breast cancer as the main cause of cancer death among European women by the middle of this decade, according to new research published in the cancer journal Annals of Oncology. In the UK and Poland it has already overtaken breast cancer as the main cause of cancer deaths in women. Researchers in Italy and Switzerland predict that just over 1.3 million people will die from cancer in the 27 countries of the European Union in 2013. Contact: Emma Mason Public Release: 11-Feb-2013
Study prompts rethink of how ovaries develop New research from the University of Adelaide will rewrite the textbooks on how an ovary is formed, as well as providing new insights into women's health and fertility. Contact: Professor Ray Rodgers, University of Adelaide Public Release: 11-Feb-2013
First-in-man study demonstrates the therapeutic effect of RNAi gene silencing in cancer treatment A study led by Dr Josep Tabernero, the Director of Clinical Research at the Vall d'Hebron Institute of Oncology and Head of the Medical Oncology Department at the Vall d'Hebron University Hospital, shows for the first time that ribonucleic acid interference is effective in the treatment of cancer patients. Harnessing these molecules to silence genes involved in the development and growth of cancer cells is an important step forward in developing a new and more targeted type of cancer therapy. Contact: Amanda Wren Public Release: 11-Feb-2013
Tumor blood vessels prevent the spread of cancer cells A lack of the protein endoglin in the blood vessels of tumor-bearing mice enables the spread of daughter tumors, according to researchers at Karolinska Institutet and Lund University, Sweden, in a study published in the scientific periodical The Journal of Experimental Medicine. Contact: Karolinska Institutet Press Office Public Release: 11-Feb-2013
Mouse model improves understanding of clear cell sarcoma Geneticists led by University of Utah Nobel Prize Laureate Mario R. Capecchi, Ph.D., have engineered mice that develop clear cell sarcoma, a significant step in better understanding how this rare and deadly soft tissue cancer arises. The mouse model also can potentially speed the development of drugs to target genes that must be activated for the cancer to form. Contact: Phil Sahm Public Release: 11-Feb-2013
Exercise linked with reduced prostate cancer risk in Caucasians but not African-Americans A new study suggests that exercise may reduce Caucasian men's risk of developing prostate cancer. And among Caucasian men who do have prostate cancer, exercise may reduce their risk of having more serious forms of the disease. Unfortunately, the benefits do not seem to apply to African-American men. Contact: Amy Molnar Public Release: 11-Feb-2013
Researchers identify genetic root to early-onset prostate cancer Prostate cancer is often considered an elderly man's disease, and little is known about the approximately 2% of cases that arise in men who are aged 50 years or younger. Research published in the February 11th issue of the Cell Press journal Cancer Cell uncovers the genetic origin of such early-onset prostate cancer. The findings could help in the development of new diagnostic, prognostic, therapeutic, and prevention strategies for the disease. Contact: Mary Beth O'Leary Public Release: 11-Feb-2013
International study suggests improved treatment alternative for lymphoid leukemia Discovering what they call the "Achilles' heel" for lymphoid leukemia, an international research team has tested a possible alternative treatment that eradicated the disease in mouse models. Reporting their results Feb. 11 in the journal Cancer Cell, the scientists said the targeted molecular therapy described in their study could have direct implications for current treatment of acute lymphoid leukemia in people. Contact: Nick Miller Public Release: 11-Feb-2013
1 disease, 2 mechanisms While prostate cancer is the most common cancer in elderly Western men it also, but more rarely, strikes patients aged between 35 and 50. Scientists at EMBL, in collaboration with several other research teams in Germany, have discovered that early-onset prostate cancers are triggered by a different mechanism from that which causes the disease at a later age. Their findings are published today in Cancer Cell, and might have important medical implications. Contact: Isabelle Kling Public Release: 11-Feb-2013
Prostate-specific antigen screening: Values and techniques shape decisions An international team of scientists led by the University of North Carolina has published a study evaluating different ways of helping men consider their values about PSA screening. They report that the decision-making process was influenced by the format in which information was presented. Contact: Dianne Shaw Public Release: 11-Feb-2013
CSHL scientists identify a new strategy for interfering with a potent cancer-causing gene About five-ten percent of cases of acute myeloid leukemia, an aggressive blood cancer that is currently incurable in 70 percent of patients, are characterized by the rearrangement of a gene called MLL (Mixed-Lineage Leukemia). Cold Spring Harbor Laboratory Assistant Professor Christopher Vakoc, M.D., Ph.D., and colleagues have identified a protein, RNF20, involved in DNA packaging that is essential for MLL-rearranged leukemia and thus presents an attractive therapeutic target. Contact: Edward Brydon Public Release: 11-Feb-2013
Synthetic circuit allows dialing gene expression up or down in human cells Scientists who built a synthetic gene circuit that allowed for the precise tuning of a gene's expression in yeast have now refined this new research tool to work in human cells, according to research published online in Nature Communications. Contact: Scott Merville Public Release: 11-Feb-2013
Deep genomic analysis identifies a micro RNA opponent for ovarian cancer Researchers employed an extensive analysis of genomic information to identify a new, high-risk cohort of ovarian cancer patients, characterize their tumors, find a potential treatment and test it in mouse models of the disease. Contact: Scott Merville Public Release: 11-Feb-2013
1-2 punch strategy against bacteria and cancer Rice University scientists are suggesting a new "combinatorial approach" to fight both drug-resistant bacteria and cancer. In this week's Proceedings of the National Academy of Sciences, a team from Rice's Center for Theoretical Biological Physics proposes using drug cocktails that contain both synthetic drug molecules and their nature-made counterparts. The synthetic drugs have a corkscrew-shaped "counterclockwise" twist not found in nature. Rice's team suggests combining them with clockwise-shaped toxins for maximum effect. Contact: Jade Boyd Public Release: 11-Feb-2013
New details on the molecular machinery of cancer New details into the activation of a cell surface protein that has been strongly linked to a large number of cancers and is a major target of cancer therapies have been reported by Berkeley Lab researchers. Contact: Lynn Yarris Public Release: 11-Feb-2013
Researchers discover 'Achilles' heel' for lymphoid leukemia An international research team coordinated at the IRCM in Montreal found a possible alternative treatment for lymphoid leukemia. Led by Dr. Tarik Moroy, the IRCM's President and Scientific Director, the team discovered a molecule that represents the disease's "Achilles' heel" and could be targeted to develop a new approach that would reduce the adverse effects of current treatments such as chemotherapy and radiation therapy. The study's results are being published today in the prestigious scientific journal Cancer Cell. Contact: Julie Langelier Public Release: 11-Feb-2013
Cancer risk for African-American women with benign breast disease factors Wayne State finds A Wayne State University researcher has identified characteristics in benign breast disease associated with future cancer risk in African-American women. Contact: Julie O'Connor Public Release: 8-Feb-2013
DAI provides potential imaging biomarker to indicate brain tumor response to RT Diffusion abnormality index (DAI) shows promise as an imaging biomarker to measure brain tumor response to radiation therapy, according to research being presented at the 2013 Cancer Imaging and Radiation Therapy Symposium. This symposium is sponsored by the American Society for Radiation Oncology and the Radiological Society of North America. Contact: Michelle Kirkwood Public Release: 8-Feb-2013
SUVmax provides valuable indicator of progression-free survival in stage I NSCLC patients SUVmax (Maximum Standardized Uptake Value) may be a significant and clinically independent marker to indicate progression-free survival in stage I non-small cell lung cancer (NSCLC) patients treated with stereotactic body radiation therapy, according to research being presented at the 2013 Cancer Imaging and Radiation Therapy Symposium. This Symposium is sponsored by the American Society for Radiation Oncology and the Radiological Society of North America. Contact: Michelle Kirkwood Public Release: 8-Feb-2013
Villain stomach bug may have a sweet side A stomach bacterium believed to cause health problems such as gastritis, ulcers, and gastric cancer may play a dual role by balancing the stomach's ecosystem and controlling body weight and glucose tolerance, according to immunologists at the Virginia Bioinformatics Institute of Virginia Tech. Contact: Tiffany Trent Public Release: 8-Feb-2013
CT texture analysis of tumors may be a valuable biomarker in localized esophageal cancer CT texture analysis of primary tumors may be a potential imaging biomarker in localized esophageal cancer following neoadjuvant chemotherapy, according to research being presented at the 2013 Cancer Imaging and Radiation Therapy Symposium. This Symposium is sponsored by the American Society for Radiation Oncology and the Radiological Society of North America. Contact: Michelle Kirkwood Public Release: 8-Feb-2013
Hepatic function testing can assist in treatment planning for liver cancer patients Monitoring the hepatic function of unresectable liver cancer patients, measured by 99mTc-labeled iminodiacetic acid via single-photon emission computed tomography prior to and during radiation therapy, provides vital information that could guide more customized treatment plans and reduce risks of liver injury, according to research being presented at the 2013 Cancer Imaging and Radiation Therapy Symposium. This Symposium is sponsored by the American Society for Radiation Oncology and the Radiological Society of North America. Contact: Michelle Kirkwood
Showing releases 1151-1175 out of 1216. << < 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 > >>
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