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Public Release: 5-May-2014
Having eczema may reduce your risk of skin cancer
Eczema caused by defects in the skin could reduce the risk of developing skin cancer, according to new research by King's College London. The immune response triggered by eczema could help prevent tumor formation by shedding potentially cancerous cells from the skin.
Medical Research Council, Wellcome Trust, Cancer Research UK

Contact: Jack Stonebridge
King's College London

Public Release: 5-May-2014
BJU International
Low testosterone levels may indicate worsening of disease for men with prostate cancer
For men with low-risk prostate cancer, low levels of testosterone may indicate a worsening of their disease.

Contact: Evelyn Martinez

Public Release: 5-May-2014
JAMA Internal Medicine
Choosing a screening method for cervical cancer: Pap alone or with HPV test
Karen Smith-McCune, M.D., Ph.D., of the University of California, San Francisco, writes: 'The updated guidelines leave physicians and other clinicians with a question: is cotesting with Pap-plus-HPV testing truly preferred over Pap testing alone (the American Cancer Society/the American Society of Colposcopy and Cervical Pathology/the American Society of Clinical Pathology recommendation), or are the options equivalent (the US Preventive Services Task Force recommendation)?'

Contact: Elizabeth Fernandez
The JAMA Network Journals

Public Release: 5-May-2014
Digestive Disease Week
Dual method to remove precancerous colon polyps may substantially reduce health-care costs
A surgical method combining two techniques for removing precancerous polyps during colonoscopies can substantially reduce the recovery time and the length of hospital stays, potentially saving the health-care system millions of dollars, according to research presented today at Digestive Disease Week.

Contact: Aimee Frank
Digestive Disease Week

Public Release: 5-May-2014
Proceedings of the National Academy of Sciences
Where DNA's copy machine pauses, cancer could be next
A comprehensive mapping of the 'fragile sites' where chromosomes are more likely to experience breakage shows the damage appears in specific areas of the genome where the DNA copying machinery is slowed or stalled during replication, either by certain sequences of DNA or by structural elements. The May 5 PNAS study could give insight into the origins of many of the genetic abnormalities seen in solid tumors.
National Institutes of Health

Contact: Karl Bates
Duke University

Public Release: 5-May-2014
Digestive Disease Week
Researchers present findings on promising biomarker for esophageal cancer
A new biomarker for esophageal cancer shows promise in improving screening for this deadly disease and its precursor, Barrett's esophagus. Amitabh Chak, M.D., of University Hospitals Case Medical Center's Seidman Cancer Center and Case Western Reserve University School of Medicine, presented findings today at Digestive Disease Week in Chicago in a research forum titled 'Aberrant Vimentin Methylation in Esophageal Brushings: A Biomarker for Detecting Barrett's Esophagus and Esophageal Adenocarcinoma.'
NIH/National Cancer Institute

Contact: Alicia Reale
University Hospitals Case Medical Center

Public Release: 5-May-2014
Molecular Systems Biology
Glutamine ratio is key ovarian cancer indicator
A Rice University-led analysis of the metabolic profiles of hundreds of ovarian tumors has revealed a new method for tailoring treatments for ovarian cancer and for assessing whether ovarian cancer cells have the potential to metastasize.
Rice's Ken Kennedy Institute, MD Anderson's Odyssey Fellows Program, National Institutes of Health, Cancer Prevention Research Institute of Texas, Gilder Foundation

Contact: Jade Boyd
Rice University

Public Release: 5-May-2014
Journal of National Cancer Institute
Focused ultrasound reduces cancer pain
Non-invasive focused ultrasound thermal therapy reduces pain from bone metastases.

Contact: Edyta Zielinska
Thomas Jefferson University

Public Release: 5-May-2014
PLOS Medicine
Liver cancer screening highly beneficial for people with cirrhosis
Liver cancer survival rates could be improved if more people with cirrhosis are screened for tumors using inexpensive ultrasound scans and blood tests, according to a review by doctors at UT Southwestern Medical Center.

Contact: Patrick McGee
UT Southwestern Medical Center

Public Release: 5-May-2014
The Oncologist
Molecular tumor board helps in advanced cancer cases
With accelerating development of personalized cancer treatments matched to a patient's DNA sequencing, proponents say front-line physicians increasingly need help to maneuver through the complex genomic landscape to find the most effective, individualized therapy.
MyAnswerToCancer, Joan and Irwin Jacobs Fund

Contact: Scott LaFee
University of California - San Diego

Public Release: 5-May-2014
Molecular Cancer Therapeutics
Bioinformatics approach helps researchers find new uses for old drug
Developing and testing a new anti-cancer drug can cost billions of dollars and take many years of research. Now using a bioinformatics approach, a team from Beth Israel Deaconess Medical Center has identified an approved antimicrobial drug that may help patients with advanced kidney cancer.
National Institutes of Health, CAPES International Fellowship

Contact: Bonnie Prescott
Beth Israel Deaconess Medical Center

Public Release: 5-May-2014
American Journal of Geriatric Psychiatry
Dementia diagnosis twice as likely if older adult has schizophrenia; cancer less likely
Regenstrief Institute and Indiana University researchers who followed over 30,000 older adults for a decade have found the rate of dementia diagnosis for patients with schizophrenia to be twice as high as for patients without this chronic, severe and disabling brain disorder. Cancer, however, was less likely.
NIH/National Institute of Mental Health, NIH/National Institute on Aging

Contact: Cindy Fox Aisen
Indiana University

Public Release: 2-May-2014
Digestive Disease Week
AGA unveils latest advances in GI research at DDW 2014
International leaders in the fields of gastroenterology and hepatology will gather together for Digestive Disease Week 2014, the largest and most prestigious gastroenterology meeting, from May 3- 6, 2014, at McCormick Place in Chicago, Ill.

Contact: Rachel Steigerwald
American Gastroenterological Association

Public Release: 2-May-2014
BMC Genomics
Novel analyses improve identification of cancer-associated genes from microarray data
Researchers a the Dartmouth Institute for Quantitative Biomedical Sciences developed a new gene expression analysis approach for identifying cancer genes. The paper entitled, 'How to get the most from microarray data: advice from reverse genomics,' was published online March 21, 2014, in BMC Genomics. The study results challenge the current paradigm of microarray data analysis and suggest that the new method may improve identification of cancer-associated genes.
National Institutes of Health, NIH/National Cancer Institute

Contact: Derik Hertel
The Geisel School of Medicine at Dartmouth

Public Release: 2-May-2014
Better sleep predicts longer survival time for women with advanced breast cancer
A new study reports that sleep efficiency, a ratio of time asleep to time spent in bed, is predictive of survival time for women with advanced breast cancer.
National Institutes of Health

Contact: Lynn Celmer
American Academy of Sleep Medicine

Public Release: 2-May-2014
Researchers find way to decrease chemoresistance in ovarian cancer
Inhibiting enzymes that cause changes in gene expression could decrease chemotherapy resistance in ovarian cancer patients, researchers at Georgia State University and the University of Georgia say.
Georgia State University

Contact: LaTina Emerson
Georgia State University

Public Release: 2-May-2014
Stem Cell Reports
A transcription factor called SLUG helps determines type of breast cancer
A study in Stem Cell Reports determines that the transcription factor SLUG plays a role in regulating stem cell function. In mice without SLUG, basal cells are reprogrammed into a luminal-cell fate, luminal cells hyper-proliferate, and stem-cell function necessary for tissue regeneration and tumor initiation is inhibited.
Breast Cancer Foundation, NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH/National Cancer Institute, NIH/National Center for Research Resources, NIH/National Center for Advancing Translational Sciences

Contact: Siobhan Gallagher
Tufts University, Health Sciences Campus

Public Release: 1-May-2014
International Journal of Clinical Practice
Risk of weight gain deters some smokers from seeking treatment to quit
Smokers may avoid treatment to quit smoking if they previously gained weight while trying to quit, according to researchers at Penn State College of Medicine.

Contact: Matthew Solovey
Penn State

Public Release: 1-May-2014
FASEB Journal
New discovery: Molecule links asthma and cancer and could aid in developing new treatments
A newly discovered molecule described in The FASEB Journal provides a new drug target for controlling both asthma-induced muscle thickening and cancerous tumor growth.

Contact: Cody Mooneyhan
Federation of American Societies for Experimental Biology

Public Release: 1-May-2014
New combination therapy developed for multiple myeloma
Each year, more than 25,000 Americans are diagnosed with multiple myeloma, a form of blood cancer that often develops resistance to therapies. However, researchers at Virginia Commonwealth University Massey Cancer Center are reporting promising results from laboratory experiments testing a new combination therapy that could potentially overcome the resistance hurdle.
NIH/National Cancer Institute, National Institutes of Health

Contact: John Wallace
Virginia Commonwealth University

Public Release: 1-May-2014
FASEB Journal
Killing Kindlin-3 to cure breast cancer: 'Blood' protein implicated
A protein believed to be limited to the hematopoietic system, called Kindlin-3, has been identified as a major player in both the formation and spread of breast cancer to other organs. This discovery, published in the May 2014 issue of The FASEB Journal, could open the door to an entirely new class of breast cancer drugs that targets this protein's newly found activity.

Contact: Cody Mooneyhan
Federation of American Societies for Experimental Biology

Public Release: 1-May-2014
Journal of Urology
Electronic nose sniffs out prostate cancer using urine samples
We may soon be able to make easy and early diagnoses of prostate cancer by smell. Investigators in Finland have established that a novel noninvasive technique can detect prostate cancer using an electronic nose. In a proof of principle study, the eNose successfully discriminated between prostate cancer and benign prostatic hyperplasia by 'sniffing' urine headspace (the space directly above the urine sample). Results using the eNose are comparable to testing prostate specific antigen, reports the Journal of Urology.

Contact: Linda Gruner
Elsevier Health Sciences

Public Release: 1-May-2014
Cell Reports
A 30-year puzzle in breast cancer is solved
In a new study published today in Cell Reports, scientists at the Fred Hutchinson Cancer Research Center demonstrate that mice lacking one copy of a gene called CTCF have abnormal DNA methylation and are markedly predisposed to cancer.

Contact: Michael Nank
Fred Hutchinson Cancer Research Center

Public Release: 1-May-2014
New myeloma-obesity research shows drugs can team with body's defenses
Obesity increases the risk of myeloma, and with obesity rates climbing particularly in the Hispanic population, Dr. Edward Medina is tracing the ways it affects cancer and use those pathways for more effective treatments.
National Institutes of Health

Contact: Elizabeth Allen
University of Texas Health Science Center at San Antonio

Public Release: 1-May-2014
International Journal of Radiation Oncology Biology Physics
Hyperfractionated RT improves local-regional control for patients with head and neck cancer
Patients with locally advanced squamous cell carcinoma of the head and neck treated with hyperfractionated radiation therapy experienced improved local-regional control and, with patients censored at five years, improved overall survival with no increase in late toxicity, according to a study published in the May 1, 2014.

Contact: Michelle Kirkwood
American Society for Radiation Oncology

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