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Showing releases 1176-1200 out of 1233.

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Public Release: 31-Mar-2014
Journal of Pathology
Novel study into breast cancer origins paves way for personalized treatment
In a new study published by the Journal of Pathology, Dr. Matt Smalley from Cardiff University treads new ground in exploring what drives breast cancers to look and behave so differently from one another.

Contact: Tomas Llewelyn Barrett
Cardiff University

Public Release: 31-Mar-2014
Epidemiology Community Health
Seven a day keeps the reaper at bay
Eating seven or more portions of fruit and vegetables a day reduces your risk of death at any point in time by 42 percent compared to eating less than one portion, reports a new UCL study.

Contact: Harry Dayantis
University College London

Public Release: 31-Mar-2014
Nature Genetics
Scientists discover a number of novel genetic defects which cause oesophageal cancer
A team of scientists from the Cancer Science Institute of Singapore at the National University of Singapore and National University Cancer Institute Singapore, and their collaborators from the Cedars-Sinai Medical Centre, UCLA School of Medicine, demonstrated that a number of novel genetic defects are able to induce oesophageal cancer.

Contact: Kimberley Wang
National University of Singapore

Public Release: 31-Mar-2014
Proceedings of the National Academy of Sciences
Using your loaf to fight brain disease
Experts analyze baker's yeast to discover potential for combating neurological conditions like Parkinson's and even cancer.
Parkinson's United Kingdom, Fundação para a Ciência e Tecnologia Portugal, others

Contact: Flaviano Giorgini
University of Leicester

Public Release: 31-Mar-2014
JAMA Internal Medicine
Aspirin use appears linked with improved survival after colon cancer diagnosis
Taking low doses of aspirin (which inhibits platelet function) after a colon cancer diagnosis appears to be associated with better survival if the tumor cells express HLA class I antigen.

Contact: Gerrit Jan Liefers
The JAMA Network Journals

Public Release: 31-Mar-2014
Oncology Nursing Forum
Mobile tools boost tobacco screening and cessation counseling
Smartphones and tablets may hold the key to getting more clinicians to screen patients for tobacco use and advise smokers on how to quit. Even though tobacco use is the leading cause of preventable disease and death in the US, clinicians often don't ask about smoking during patient exams.
NIH/National Cancer Institute, NIH/National Institute of Nursing Research

Contact: Lisa Rapaport
Columbia University Medical Center

Public Release: 30-Mar-2014
Nature Genetics
Genetic mutations warn of skin cancer risk
In a study published in Nature Genetics, researchers have discovered that mutations in a specific gene are responsible for a hereditary form of skin cancer. These mutations inactivate the POT1 gene that protects our chromosomes, and, in turn, results in skin cancer. The mechanism that underlies this form of skin cancer is also a potential target for drug development in this subset of melanoma patients.

Contact: Aileen Sheehy
Wellcome Trust Sanger Institute

Public Release: 29-Mar-2014
ACMG 2014 Annual Clinical Genetics Meeting
New approach to leukemia testing may better define prognosis, treatment
Nearly half of patients with the most common form of adult leukemia are said to have normal chromosomes but appear instead to have a distinct pattern of genetic abnormalities that could better define their prognosis and treatment, researchers report.

Contact: Toni Baker
Medical College of Georgia at Georgia Regents University

Public Release: 28-Mar-2014
Clinical Cancer Research
Gene may predict if further cancer treatments are needed
University of Texas Southwestern Medical Center researchers are developing a new predictive tool that could help patients with breast cancer and certain lung cancers decide whether follow-up treatments are likely to help.

Contact: Patrick McGee
UT Southwestern Medical Center

Public Release: 28-Mar-2014
ELCC 2014 European Lung Cancer Conference
Call for more awareness of sexual dysfunction in lung cancer patients
Many lung cancer patients suffer difficulties with sexual expression and intimacy, yet for too long the topic has been ignored by doctors and researchers, experts have said at the 4th European Lung Cancer Conference.

Contact: ELCC Press Office
European Society for Medical Oncology

Public Release: 28-Mar-2014
Journal of the National Cancer Institute
Adjuvant chemotherapy increases markers of molecular aging in the blood of BC survivors
Adjuvant chemotherapy for breast cancer is 'gerontogenic,' accelerating the pace of physiologic aging, according to a new study published March 28 in the Journal of the National Cancer Institute.

Contact: Zachary Rathner
Oxford University Press USA

Public Release: 28-Mar-2014
Journal of the National Cancer Institute
UNC researchers show cancer chemotherapy accelerates 'molecular aging'
Using a test developed at UNC Lineberger Comprehensive Cancer Center to determine molecular aging, UNC oncologists have directly measured the impact of anti-cancer chemotherapy drugs on biological aging.
National Institutes of Health, Paul Glenn Foundation, Burroughs Wellcome Fund, Breast Cancer Research Foundation

Contact: William Davis
University of North Carolina Health Care

Public Release: 27-Mar-2014
Cancer Research
QUB discovery signals new treatment for those at high risk of breast and ovarian cancer
Cancer researchers at Queen's University Belfast have made a breakthrough which could signal new treatments for women at high risk of breast and ovarian cancer. The new discovery by researchers in Queen's Centre for Cancer Research and Cell Biology may mean women affected with BRCA1 could use drugs, which are already available, to reduce their risk of developing the disease, rather than undergo irreversible surgery.
Cancer Research United Kingdom, Cancer Focus Northern Ireland

Contact: Una Bradley
Queen's University Belfast

Public Release: 27-Mar-2014
British Journal of Surgery
Faster genetic testing method will likely transform care for patients with breast cancer
Faster and cheaper DNA sequencing techniques will likely improve care for patients with breast cancer but also create challenges for clinicians as they counsel patients on their treatment options. Those are among the conclusions of a study published recently in the British Journal of Surgery. The findings provide insights into how genetic advances will soon be affecting patient care.

Contact: Evelyn Martinez

Public Release: 27-Mar-2014
Cell Reports
Scientists find potential target for treating mitochondrial disorders
Whitehead Institute scientists have identified a protein whose inhibition could hold the key to alleviating suffering caused by mitochondrial disorders found in cancer, Parkinson's disease, Alzheimer's disease, and mitochondrial diseases.
National Institutes of Health, David H. Koch Institute for Integrative Cancer Research, Alexander and Margaret Stewart Trust Fund

Contact: Nicole Giese Rura
Whitehead Institute for Biomedical Research

Public Release: 27-Mar-2014
Cancer Cell
Researchers at IRB discover a key regulator of colon cancer
A team headed by Angel R. Nebreda at the Institute for Research in Biomedicine demonstrates thatp38 is required for the survival and proliferation of colon cancer cells, thus favoring tumor growth. The study is published today in Cancer Cell, a journal with one of the highest impact factors in cancer research.
BBVA Foundation, European Union funds (InflaCare project), European Research Council, Spanish Government

Contact: Sònia Armengou
Institute for Research in Biomedicine (IRB Barcelona)

Public Release: 27-Mar-2014
Nature Medicine
Mechanical forces driving breast cancer lead to key molecular discovery
The stiffening of breast tissue in breast-cancer development points to a new way to distinguish a type of breast cancer with a poor prognosis from a related, but often less deadly type, UC San Francisco researchers have found in a new study.
US Department of Defense Breast Cancer Research Program, Susan G. Komen, National Institutes of Health

Contact: Jeffrey Norris
University of California - San Francisco

Public Release: 27-Mar-2014
European Journal of Cancer
Researchers: Biomarkers predict effectiveness of radiation treatments for cancer
An international team of researchers, led by Beaumont Health System's Jan Akervall, M.D., Ph.D., looked at biomarkers to determine the effectiveness of radiation treatments for patients with squamous cell cancer of the head and neck. They identified two markers that were good at predicting a patient's resistance to radiation therapy. Their findings were published in the February issue of the European Journal of Cancer.
Beaumont Health System, Lund University, Van Andel Institute

Contact: Robert Ortlieb
Beaumont Health System

Public Release: 27-Mar-2014
Cancer Cell
Adult cancer drugs show promise against an aggressive childhood brain tumor
The quest to improve survival of children with a high-risk brain tumor has led St. Jude Children's Research Hospital investigators to two drugs already used to treat adults with breast, pancreatic, lung and other cancers. The study was published today online ahead of print in the journal Cancer Cell.
National Institutes of Health, French National Cancer Institute, Centre national de la recherche scientifique, Institut Curie, Necker Hospital, V Foundation, American-Lebanese-Syrian Associated Charities

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Public Release: 27-Mar-2014
Fertility and Sterility
Study shows promise of preserving fertility in boys with cancer
Scientists have moved a step closer to being able to preserve fertility in young boys who undergo chemotherapy and radiation treatments for cancer. Scientists aim to freeze a sample of the boys' testicular tissue so that when they reach adulthood, spermatogonial stem cells found in the tissue can be reproduced and transplanted back into the patients.

Contact: Karen Richardson
Wake Forest Baptist Medical Center

Public Release: 27-Mar-2014
Proceedings of the National Academy of Sciences
Cancer researchers find key protein link
A new understanding of proteins at the nexus of a cell's decision to survive or die has implications for researchers who study cancer and age-related diseases.
National Institutes of Health, Cancer Prevention Research Institute of Texas, Israeli Science Foundation, European Research Council

Contact: David Ruth
Rice University

Public Release: 26-Mar-2014
American Association for Cancer Research (AACR) Annual Meeting 2014
Albert Einstein College of Medicine researchers present at AACR Annual Meeting symposia
From uncovering the role nerve cells play in metastasis to identifying new cancer-causing genes, researchers at Albert Einstein College of Medicine of Yeshiva University made notable advances in the understanding and potential treatment of cancer during the past year. Several Einstein faculty members and students will present their recent research at the American Association for Cancer Research (AACR) Annual Meeting, taking place in San Diego April 5-9, 2014.

Contact: Kim Newman
Albert Einstein College of Medicine

Public Release: 26-Mar-2014
Journal of Nuclear Medicine
Preoperative PET cuts unnecessary lung surgeries in half
A comprehensive statistical analysis reveals PET changed patient management in 50 percent of lung cancer cases.

Contact: Eleanore Tapscott
Society of Nuclear Medicine

Public Release: 26-Mar-2014
UT Southwestern cancer biologists link tumor suppressor gene to stem cells
Just as archeologists try to decipher ancient tablets to discern their meaning, UT Southwestern Medical Center cancer biologists are working to decode the purpose of an ancient gene considered one of the most important in cancer research.
Cancer Prevention and Research Institute of Texas, Ellison Foundation, NIH/National Institute of General Medical Sciences, Welch Foundation

Contact: Patrick McGee
UT Southwestern Medical Center

Public Release: 26-Mar-2014
European Journal of Pharmacology
Natural plant compounds may assist chemotherapy
Researchers at Plant & Food Research have identified plant compounds present in carrots and parsley that may one day support more effective delivery of chemotherapy treatments.

Contact: Mike Shaw
New Zealand Institute for Plant and Food Research

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