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Showing releases 1176-1200 out of 1265.

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Public Release: 5-Mar-2014
New England Journal of Medicine
Younger men benefit most from surgery for localized prostate cancer
New study finds a substantial long-term reduction in mortality for men with localized cancer who undergo a radical prostatectomy.
Swedish Cancer Society, National Institutes of Health, Karolinska Institutet, Prostate Cancer Foundation, Percy Falk Foundation

Contact: Todd Datz
Harvard School of Public Health

Public Release: 4-Mar-2014
European Journal of Public Health
Screening does not shift breast cancer to earlier stages
New research from Aarhus University suggests that screening for breast cancer results in increased diagnoses of early stage cancer -- but without a similarly sized decrease in the more serious and aggressive cases.

Contact: Henrik Stovring
Aarhus University

Public Release: 4-Mar-2014
Cell Metabolism
Meat and cheese may be as bad for you as smoking
A high-protein diet during middle age makes you nearly twice as likely to die and four times more likely to die of cancer, but moderate protein intake is good for you after 65.
NIH/National Institute of Aging, USC Norris Cancer Center

Contact: Suzanne Wu
University of Southern California

Public Release: 4-Mar-2014
Cell Metabolism
Controlling protein intake may be key to a long and healthy life
While it's clear that diet can affect longevity, there's great uncertainty about which combinations of foods are best for attaining a long and healthy life. Now two groups of researchers publishing in the March 4 issue of the Cell Press journal Cell Metabolism each suggest that low protein intake may be a key factor, at least until old age.

Contact: Mary Beth O'Leary
Cell Press

Public Release: 4-Mar-2014
Molecular Cancer Research
TGen identifies key protein that helps prevent lung cancer tumors from being destroyed
Researchers at the Translational Genomics Research Institute have discovered a protein, Mcl-1, that helps enable one of the most common and deadly types of cancer to survive radiation and drug treatments. In a new laboratory study published in the scientific journal Molecular Cancer Research, TGen investigators found that a protein called Mcl-1 helps enable TWEAK-Fn14, which in turn helps protect NSCLC tumors from being destroyed by radiation and drugs.
National Institutes of Health

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 4-Mar-2014
British Medical Journal
Does palliative chemotherapy palliate?
Terminal cancer patients who receive chemotherapy in the last months of their lives are less likely to die where they want and are more likely to undergo invasive medical procedures than those who do not receive chemotherapy, according to research in this week's BMJ.
NIH/National Cancer Institute, NIH/National Institute of Mental Health

Contact: Jennifer Gundersen
Weill Cornell Medical College

Public Release: 4-Mar-2014
Cell Metabolism
Cholesterol study suggests new diagnostic, treatment approach for prostate cancer
Researchers have discovered a link between prostate cancer aggressiveness and the accumulation of a compound produced when cholesterol is metabolized in cells, findings that could bring new diagnostic and treatment methods. Findings also suggest that a class of drugs previously developed to treat atherosclerosis might be repurposed for treatment of advanced prostate cancer.
National Institutes of Health, National Science Foundation, US Department of Defense

Contact: Emil Venere
Purdue University

Public Release: 4-Mar-2014
Journal of Clinical Oncology
Investigational drug may increase survival for some patients with advanced melanoma
An experimental drug aimed at restoring the immune system's ability to spot and attack cancer-halted cancer progression or shrank tumors in patients with advanced melanoma, according to a multi-site, early-phase clinical trial at Johns Hopkins Kimmel Cancer Center and 11 other institutions. All patients had experienced disease progression despite prior systemic therapies, and most had received two or more prior treatments.

Contact: Vanessa Wasta
Johns Hopkins Medicine

Public Release: 4-Mar-2014
Common cancers evade detection by silencing parts of immune system cells
Johns Hopkins researchers say they have identified a set of genes that appear to predict which tumors can evade detection by the body's immune system, a step that may enable them to eventually target only the patients most likely to respond best to a new class of treatment.
NIH/National Cancer Institute, Stand Up to Cancer, Epigenetic Dream Team

Contact: Stephanie Desmon
Johns Hopkins Medicine

Public Release: 4-Mar-2014
Brain, Behavior and Immunity
Imprint of chemotherapy linked to inflammation in breast cancer survivors
Chemotherapy can leave a long-lasting epigenetic imprint in the DNA of breast cancer patients' blood cells. That imprint is associated with biological signs of inflammation up to six months after the completion of treatment.
NIH/National Cancer Institute

Contact: Quinn Eastman
Emory Health Sciences

Public Release: 3-Mar-2014
Journal of Experimental Medicine
Eliminating bacteria, changing lifestyle could lower risk in people genetically susceptible to colorectal cancer
Using a transgenic mouse model, Mount Sinai researchers found that the intestinal polyps depend on gut bacteria and that antibiotic treatment eradicated the bacteria and prevented polyp formation. They propose that bacteria in the gut cross into the intestine promoting inflammation and tumor growth.
National Institutes of Health

Contact: Sid Dinsay
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 3-Mar-2014
Current Medical Research and Opinion
Myriad publishes clinical utility study for Prolaris
Data from the PROCEDE 500 study published in the journal Current Medical Research and Opinion demonstrate that 65 percent of physicians changed their original treatment plans for men with prostate cancer based on results from the Prolaris test.

Contact: Ronald Rogers
Myriad Genetics, Inc.

Public Release: 3-Mar-2014
Clinical Cancer Research
Ancient Chinese medicine put through its paces for pancreatic cancer
The bark of the Amur cork tree has traveled a centuries-long road with the healing arts. Now it is being put through its paces by science in the fight against pancreatic cancer, with the potential to make inroads against several more.
NIH/National Center for Complementary and Alternate Medicine

Contact: Elizabeth Allen
University of Texas Health Science Center at San Antonio

Public Release: 3-Mar-2014
Journal of Clinical Oncology
Yoga regulates stress hormones and improves quality of life for women with breast cancer undergoing radiation therapy
For women with breast cancer undergoing radiation therapy, yoga offers unique benefits beyond fighting fatigue, according to research from The University of Texas MD Anderson Cancer Center.

Contact: William Fitzgerald
University of Texas M. D. Anderson Cancer Center

Public Release: 3-Mar-2014
Nature Methods
Homing in on cancer with a comprehensive measurement method
Whether a tumor develops from individual cancer cells and whether metastases are formed depends on many factors in the affected tissue. A greater understanding of a tumor's complex switch and control circuits could help to combat cancer in a more targeted fashion. Re-searchers at the University of Zurich have come up with an imaging method that is able to simultaneously visualize a previously unachieved number of factors involved in cancer.

Contact: Bernd Bodenmiller
University of Zurich

Public Release: 3-Mar-2014
Proceedings of the National Academy of Sciences
Big stride in understanding PP1, the ubiquitous enzyme
The enzyme PP1 has a key role in many of the body's healthy functions and diseases. It's so generally important that drug developers dare not target it. In a new study in the Proceedings of the National Academy of Sciences, Brown University scientists report a big leap in understanding how PP1 interacts with other proteins to behave specifically in distinct situations. That could lead to medicines that target it for precise benefits.
NIH/National Institute of General Medical Sciences

Contact: David Orenstein
Brown University

Public Release: 3-Mar-2014
Proceedings of the National Academy of Sciences
Researchers identify 'carbohydrates in a coal mine' for cancer detection
Researchers at New York University and the University of Texas at Austin have discovered that carbohydrates serve as identifiers for cancer cells. Their findings show how these molecules may serve as signals for cancer and explain what's going on inside these cells, pointing to new ways in which sugars function as a looking glass into the workings of their underlying structures.
National Institutes of Health

Contact: James Devitt
New York University

Public Release: 3-Mar-2014
Nanomedicine: Nanotechnology, Biology, and Medicine
Dartmouth researchers find promising results with local hyperthermia of tumors
A combination of iron-oxide nanoparticles and an alternating magnetic field, which together generate heat, have activated an immune system response to tumors in mice according to an accepted manuscript by Dartmouth-Hitchcock Norris Cotton Center researchers in the journal Nanomedicine: Nanotechnology, Biology and Medicine.
National Institutes of Health, NIH/National Institute of General Medical Sciences

Contact: Donna Dubuc
The Geisel School of Medicine at Dartmouth

Public Release: 3-Mar-2014
Frontiers in Oncology
Researchers develop antibody-targeted treatment for recurrent small-cell lung cancer
Researchers at Norris Cotton Cancer Center have found an antibody that may be used in future treatments for recurrent small-cell lung cancer, which currently has no effective therapy. The mouse monoclonal antibody they have developed, MAG-1, targets the ProAVP surface marker. When given alone, it significantly slows the growth of tumor xenografts of human recurrent small-cell lung cancer in mice.
Woomera Therapeutics Inc.

Contact: Donna Dubuc
The Geisel School of Medicine at Dartmouth

Public Release: 3-Mar-2014
Journal of Clinical Investigation
JCI online ahead of print table of contents for March 3, 2014
This release contains summaries, links to PDFs, and contact information for the following newsworthy papers published online, March 3, 2014 in the JCI: 'Identification of factors that influence breast cancer metastasis to bone,' 'Assembly of the cochlear gap junction macromolecular complex requires connexin 26,' 'SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome,' 'Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosis,' 'Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy,' and more.

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 3-Mar-2014
Journal of Urology
Reliable pretreatment information assists prostate cancer patients in decision-making
Men who have been diagnosed with prostate cancer need to assimilate information rapidly in order to weigh the treatment options and make informed decisions. Although patients consult a variety of information sources, outcome information that is specific to the treating physician leads to greater patient satisfaction following treatment, according to a new study published in The Journal of Urology®.

Contact: Linda Gruner
Elsevier Health Sciences

Public Release: 3-Mar-2014
PSRC 59th Annual Meeting
New approach to breast reconstruction surgery reduces opioid painkiller use
A new approach to breast reconstruction surgery aimed at helping patients' bodies get back to normal more quickly cut their postoperative opioid painkiller use in half and meant a day less in the hospital on average, a Mayo Clinic study found. The method includes new pain control techniques, preventive anti-nausea treatment and getting women eating and walking soon after free flap breast reconstruction surgery. It has proved so effective, it is now being used across plastic surgery at Mayo Clinic.

Contact: Sharon Theimer
Mayo Clinic

Public Release: 3-Mar-2014
British Journal of Cancer
Report reveals cancer drug divide
Patients suffering from cancer in England are up to seven times more likely to be prescribed expensive cancer drugs than fellow sufferers in Wales, a new study assessing the impact of the Cancer Drugs Fund has revealed.
National Institute for Health Research

Contact: Philippa Walker
University of Bristol

Public Release: 3-Mar-2014
Journal of Clinical Oncology
Immune system-based therapy produces lasting remissions in melanoma patients
A drug that unleashes the immune system to attack cancer can produce lasting remissions and hold the disease in check -- for more than two years, in some cases -- in many patients with advanced melanoma, according to a new study.
Bristol-Myers Squibb

Contact: Teresa Herbert
Dana-Farber Cancer Institute

Public Release: 3-Mar-2014
AGA journals highlight seminal new CRC research
In support of Colorectal Cancer (CRC) Awareness Month, the American Gastroenterological Association would like to highlight important new CRC research appearing in the March issues of Clinical Gastroenterology and Hepatology and Gastroenterology.

Contact: Rachel Steigerwald
American Gastroenterological Association

Showing releases 1176-1200 out of 1265.

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