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Showing releases 1176-1200 out of 1210. << < 43 | 44 | 45 | 46 | 47 | 48 | 49 > >>
Public Release: 29-Nov-2012
Study sheds light on how pancreatic cancer begins Research led by scientists at the University of California, San Diego and UC San Francisco Schools of Medicine examined the tumor-initiating events leading to pancreatic cancer (also called pancreatic ductal adenocarcinoma or PDA) in mice. Their work, published on line November 29 in the journal Cancer Cell, may help in the search for earlier detection methods and treatments. Contact: Debra Kain Public Release: 29-Nov-2012
Delayed treatment for advanced breast cancer has 'profound effect' Results from a recent study show women who wait more than 60 days to begin treatment for advanced breast cancer face significantly higher risks of dying than women who start therapy shortly after diagnosis. Contact: Marti Leitch Public Release: 29-Nov-2012
Understanding of the mechanisms of drug resistance to dual-agent chemotherapy in ovarian cancer A study published today in the open-access Journal of Ovarian Research provides novel information that further adds to clinicians' understanding of the mechanisms involved in the development of resistance to dual-agent chemotherapy. Contact: Hilary Glover Public Release: 29-Nov-2012
Study helps resolve debate about how tumors spread A team of scientists, led by researchers at the University of California, San Diego School of Medicine, has shown for the first time how cancer cells control the ON/OFF switch of a program used by developing embryos to effectively metastasize in vivo, breaking free and spreading to other parts of the body, where they can proliferate and grow into secondary tumors. Contact: Scott LaFee Public Release: 29-Nov-2012
Researchers create a fly to study how a normal cell turns cancerous The wing of a fruit fly may hold the key to unraveling the genetic and molecular events that transform a normal cell into a cancerous one. The study, conducted on Drosophila melanogaster by scientists at the IRB Barcelona has reproduced each of the steps known to take place when a healthy cell turns cancerous. The researchers have thus provided an inexpensive and effective model that will allow to scrutinize the genes and molecules involved in each step. Contact: Sònia Armengou Public Release: 29-Nov-2012
New genetic test detects early breast cancer and identifies future risk Breast cancer detection has improved, but more work remains to ensure accurate diagnosis, and to assess future risk. Researchers are developing a test of gene action that predicts cancer risk at first diagnosis, and into the future. This research in The FASEB Journal discusses how genetic switches, which are turned on and off in regular cellular development, can be analyzed in minute detail to determine the presence, or risk, of breast cancer growth. Contact: Cody Mooneyhan Public Release: 28-Nov-2012
COUP-TFII sparks prostate cancer progression Which cancers are essentially indolent and present no risk and which are life threatening? Which can be watched and which need aggressive treatment? Drs. Ming-Jer and Sophia Tsai both professors in the department of molecular and cellular biology at Baylor College of Medicine, think a receptor called COUP-TFII that they have long studied may point the way to an answer. Contact: Dipali Pathak Public Release: 28-Nov-2012
Potentially toxic flame retardants found in many US couches More than half of all couches tested in a Duke University-led study contained potentially toxic or untested chemical flame retardants that may pose risks to human health. Contact: Tim Lucas Public Release: 28-Nov-2012
Combined RB and PTEN loss identifies DCIS primed for invasive breast cancer The combined loss of two tumor suppressor genes, retinoblastoma and phosphatase and tensin homolog was shown to be strongly associated with progression of DCIS to invasive breast cancer, according to a study published Nov. 28 in the Journal of the National Cancer Institute. Contact: Zachary Rathner Public Release: 28-Nov-2012
KRAS and BRAF mutation screening in metastatic colorectal cancer costly in relation to benefits Researchers report that screening for KRAS and BRAF mutations can reduce the cost of anti-EGFR treatment for metastatic colorectal cancer but with a very small reduction in overall survival according to a new study published on Nov. 28 in the Journal of the National Cancer Institute. Contact: Zachary Rathner Public Release: 28-Nov-2012
New study: Many flame retardants in house dust -- unsafe levels In Silent Spring Institute's new peer-reviewed study of the largest number of flame retardants ever tested in homes, we found that most houses had levels of at least one flame retardant that exceeded a federal health guideline. Contact: Kathryn Rodgers Public Release: 28-Nov-2012
NSAID use linked to reduced hepatocellular carcinoma risk and mortality due to chronic liver disease Researchers found that aspirin use is associated with a decreased risk of developing hepatocellular carcinoma and death from chronic liver disease, according to a study published Nov. 28 in the Journal of the National Cancer Institute. Contact: Zachary Rathner Public Release: 28-Nov-2012
Johns Hopkins scientists pair blood test and gene sequencing to detect cancer Scientists at the Johns Hopkins Kimmel Cancer Center have combined the ability to detect cancer DNA in the blood with genome sequencing technology in a test that could be used to screen for cancers, monitor cancer patients for recurrence and find residual cancer left after surgery. Contact: Vanessa Wasta Public Release: 28-Nov-2012
Analysis of conflicting fish oil studies finds that omega-3 fatty acids still matter A new analysis helps to sort through conflicting findings from literally hundreds of studies on use of omega-3 fatty acids for heart disease. It concludes that they still matter; they do work; and that modern therapies for cardiovascular disease help to mask the benefits omega-3 consumption might otherwise provide. Contact: Donald Jump Public Release: 28-Nov-2012
Ponatinib acts against the most resistant types of chronic myeloid leukemia A previously invincible mutation in chronic myeloid leukemia has been thwarted by an investigational drug in a phase I clinical trial reported in the current edition of the New England Journal of Medicine. Contact: Scott Merville Public Release: 28-Nov-2012
Researchers report first success of targeted therapy in most common non-small cell lung cancer A new study by an international team of investigators led by Dana-Farber Cancer Institute scientists is the first to demonstrate that chemotherapy and a new, targeted therapy work better in combination than chemotherapy alone in treating patients with the most common genetic subtype of lung cancer. Contact: Robbin Ray Public Release: 28-Nov-2012
Experts recommend closer scrutiny of radiation exposure from CT scans Amid increasing fear of overexposure to radiation from CT scans, a panel of experts has recommended more research on the health effects of medical imaging and ways to reduce unnecessary CT tests, as well as industry standardization of CT machines. Contact: Dorsey Griffith Public Release: 28-Nov-2012
Studies from 2012 Quality Care Symposium highlight findings in improving quality of cancer care Five additional studies to be presented at the 2012 Quality Care Symposium provide insight on how oncology practices can improve the quality of care they provide. The Symposium will take place Nov. 30 - Dec. 1, at the Manchester Grand Hyatt in San Diego. Contact: Aaron Tallent Public Release: 28-Nov-2012
Scripps Florida scientists uncover a novel cooperative effort to stop cancer spread Scientists from the Florida campus of The Scripps Research Institute have uncovered a group of what have been considered relatively minor regulators in the body that band together to suppress the spread of cancer from its primary site. Contact: Eric Sauter Public Release: 27-Nov-2012
Tracking down smallest biomarkers A new device is to provide the metrological basis for promising biomarkers. The vacuum-compatible version of the Pilatus hybrid pixel detector for X-rays, which was developed by Dectris in cooperation with the Physikalisch-Technische Bundesanstalt, allows the size of nano-particles -- which, to date, have been difficult to characterize -- to be determined using small-angle X-ray scattering at low photon energies. Contact: Michael Krumrey Public Release: 27-Nov-2012
Most women who have double mastectomy don't need it, U-M study finds About 70 percent of women who have both breasts removed following a breast cancer diagnosis do so despite a very low risk of facing cancer in the healthy breast, new research from the University of Michigan Comprehensive Cancer Center finds. Contact: Nicole Fawcett Public Release: 27-Nov-2012
Research reveals new understanding of X chromosome inactivation In a paper published in the Nov. 21 issue of Cell, a team led by Mauro Calabrese, a postdoctoral fellow at the University of North Carolina in the lab of Terry Magnuson, chair of the department of genetics and member of the UNC Lineberger Comprehensive Cancer Center, broadens the understanding of how cells regulate silencing of the X chromosome in a process known as X-inactivation. Contact: William Davis Public Release: 27-Nov-2012
Scripps Research Institute study points to potential new therapies for cancer and other diseases Researchers at the Scripps Research Institute are fueling the future of cancer treatment by improving a powerful tool in disease defense: the body's immune system. By revealing a novel but widespread cell signaling process, the scientists may have found a way to manipulate an important component of the immune system into more effectively fighting disease. Contact: Mika Ono Public Release: 27-Nov-2012
Research from ASCO'S Quality Care Symposium shows advances and challenges in improving the quality of cancer care New studies released today reveal important advances in cancer care quality measurement, physician adherence to quality standards, and end-of-life care, while highlighting the overuse of contralateral prophylactic mastectomy. The studies were released in a presscast today in advance of ASCO's inaugural 2012 Quality Care Symposium. The Symposium will take place Nov. 30 – Dec. 1, 2012, at the Manchester Grand Hyatt in San Diego. Contact: Aaron Tallent Public Release: 27-Nov-2012
New mechanism for cancer progression discovered by UNC and Harvard researchers University of North Carolina Lineberger Comprehensive Cancer Center and Harvard researchers have discovered an alternative mechanism for activating rhe oncogene Ras that does not require mutation or hormonal stimulus. Contact: William Davis
Showing releases 1176-1200 out of 1210. << < 43 | 44 | 45 | 46 | 47 | 48 | 49 > >>
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