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Showing releases 1176-1200 out of 1258.

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Public Release: 14-Oct-2014
Journal of Sexual Medicine
Side effects of cancer prevention surgery can be helped with education program
More women are having ovary-removing surgery as a cancer prevention measure, but many are often unaware of sexual or psychological side effects of the procedure. A new study by researchers at Dana-Farber Cancer Institute shows a half-day educational program can help successfully deal with these issues by educating women on how to address them.
NIH/National Cancer Institute

Contact: Anne Doerr
Dana-Farber Cancer Institute

Public Release: 14-Oct-2014
Thyroid carcinoma: Biomarker reveals cancer cause
The expression of the protein CLIP2 provides information on whether a papillary thyroid carcinoma was induced by radiation or had a sporadic origin. With this discovery, scientists from the Helmholtz Zentrum München have identified a new biomarker for the diagnosis of the cancer cause. Their findings have been published in the journal 'Oncogene.'

Contact: Dr. Julia Heß
Helmholtz Zentrum München - German Research Center for Environmental Health

Public Release: 14-Oct-2014
PLOS Biology
Scientists find molecular 'breadcrumb trail' that helps melanoma spread
Cancer Research UK scientists have discovered that melanoma cells are drawn to follow the 'trail' of a naturally-occurring molecule in the body, which directs this serious type of skin cancer to spread, according to research published in PLOS Biology.
Cancer Research UK

Contact: Emily Head
Cancer Research UK

Public Release: 14-Oct-2014
Clinical Cancer Research
University of Calgary research leads to brain cancer clinical trial
Researchers at the University of Calgary have made a discovery that could prolong the life of people living with glioblastoma -- the most aggressive type of brain cancer. The research was published in Clinical Cancer Research, and is leading researchers to start a human phase I/II clinical trial as early as spring 2015.
Alberta Cancer Foundation, Alberta Innovates-Health Solutions, Canadian Stem Cell Network

Contact: Marta Cyperling
University of Calgary, Faculty of Medicine

Public Release: 14-Oct-2014
Study sheds light on factors that may contribute to pancreatic cancer
New research that provides a better understanding of pancreatic cancer may help identify individuals at increased risk.

Contact: Evelyn Martinez

Public Release: 14-Oct-2014
PLOS Biology
Scientists find molecular 'breadcrumb trail' that helps melanoma spread
Cancer Research UK scientists have discovered that melanoma cells are drawn to follow the 'trail' of a naturally-occurring molecule in the body, which directs this serious type of skin cancer to spread, according to research publishing Tuesday Oct. 14 in the open access journal PLOS Biology.
Cancer Research UK

Contact: Press Office

Public Release: 14-Oct-2014
Annals of Oncology
EMA open to discuss use of complementary methodologies for rare cancers
Rare Cancers Europe (RCE) is a multi stakeholder initiative promoted by ESMO dedicated to putting rare cancers on the European political agenda. In their consensus document, RCE argue that a higher degree of uncertainty should be accepted for regulatory as well as clinically informed decision-making in rare cancers, to overcome the limitations imposed by small population trials.

Contact: Rare Cancers Europe
European Society for Medical Oncology

Public Release: 14-Oct-2014
Early detection window when pancreatic cancer is in the family
Pancreatic cancer likely takes between 10 and 20 years to develop, providing the potential for a very 'broad window' of intervention if detected early, which may be possible for people who inherit a predisposition, say Australian clinical researchers.
National Health and Medical Research Council of Australia, Cancer Council NSW, Cancer Institute NSW, Queensland Government, Institute of Molecular Bioscience at the University of Queensland, Avner Nahmani Pancreatic Cancer Foundation

Contact: Alison Heather
Garvan Institute of Medical Research

Public Release: 13-Oct-2014
JAMA Internal Medicine
Study estimates 14 million smoking-attributable major medical conditions in US
Adults in the United States suffered from approximately 14 million major medical conditions attributable to smoking.

Contact: Jenny Haliski
The JAMA Network Journals

Public Release: 13-Oct-2014
Nearly 1 in 3 UK lung cancer patients dies within 3 months of diagnosis
Nearly one in three lung cancer patients in the UK dies within three months of diagnosis, despite having visited their family doctor several times beforehand, reveals an analysis of primary care data, published online in the journal Thorax.
Roy Castle Lung Foundation

Contact: Emma Dickinson

Public Release: 13-Oct-2014
Proceedings of the National Academy of Sciences
Greater rates of mitochondrial mutations discovered in children born to older mothers
The discovery of a 'maternal age effect' could be used to predict the accumulation of mitochondrial DNA mutations in maternal egg cells -- and the transmission of these mutations to children. These mutations cause more than 200 diseases and contribute to others such as diabetes, cancer, Parkinson's disease, and Alzheimer's disease.
Penn State University, Pennsylvania Department of Health, Battelle Memorial Institute

Contact: Barbara K. Kennedy
Penn State

Public Release: 13-Oct-2014
How metastases develop in the liver
Most tumors are only fatal if the cancer cells spread in the body and form secondary tumors, known as metastases, in other organs, such as the liver. Scientists at Klinikum rechts der Isar of Technische Universität München have now shown that increased amounts of a particular protein in the liver create favorable conditions for the implantation of cancer cells and thus for the formation of metastases. The researchers have already succeeded in preventing these processes in an animal model.

Contact: Vera Siegler
Technische Universitaet Muenchen

Public Release: 13-Oct-2014
Developmental Cell
Sonic Hedgehog protein causes DNA damage and the development child brain tumors
Scientists at the Institut de recherches cliniques de Montreal and the University of Montreal discovered a mechanism that promotes the progression of medulloblastoma, the most common brain tumor found in children.
Canadian Institutes of Health Research, Canadian Cancer Society, Cancer Research Society

Contact: William Raillant-Clark
University of Montreal

Public Release: 13-Oct-2014
Cancer Cell
New cancer drug to begin trials in multiple myeloma patients
Scientists at Imperial College London have developed a new cancer drug which they plan to trial in multiple myeloma patients by the end of next year.
Medical Research Council, National Institutes of Health, Cancer Research UK

Contact: Sam Wong
Imperial College London

Public Release: 13-Oct-2014
Cancer Research
Oral drug reduces formation of precancerous polyps in the colon, UB researchers find
Inflammatory cells in the colon, or polyps, are very common after the age of 50. The average 60-year-old has an estimated 25 percent chance of having polyps. Most polyps are benign, but some will develop into colon cancer. Now, an oral drug has successfully treated chronic, precancerous inflammation in the intestine in an animal study.
National Institutes of Health, Howard Hughes Medical Institute

Contact: Ellen Goldbaum
University at Buffalo

Public Release: 13-Oct-2014
Journal of American Chemical Society
Bio-inspired 'nano-cocoons' offer targeted drug delivery against cancer cells
Biomedical engineering researchers have developed a drug delivery system consisting of nanoscale 'cocoons' made of DNA that target cancer cells and trick the cells into absorbing the cocoon before unleashing anticancer drugs.

Contact: Matt Shipman
North Carolina State University

Public Release: 13-Oct-2014
Journal of Occupational and Environmental Medicine
QUT study helps outdoor workers reduce their skin cancer risk
Skin cancer is one of the biggest fears for one in two outdoor workers and when the boss and staff work together the sun safe message gets through, a QUT study has found.
Queensland Government

Contact: Sandra Hutchinson
Queensland University of Technology

Public Release: 13-Oct-2014
Genome Research
PTPRZ-MET fusion protein: A new target for personalized brain cancer treatment
Researchers at the University of California, San Diego School of Medicine have identified a new fusion protein found in approximately 15 percent of secondary glioblastomas or brain tumors. The finding offers new insights into the cause of this cancer and provides a therapeutic target for personalized oncologic care.
Sontag Foundation, Burroughs Wellcome Foundation, Kimmel Foundation, Doris Duke Foundation, Forbeck Foundation

Contact: Jackie Carr
University of California - San Diego

Public Release: 13-Oct-2014
Proceedings of the National Academy of Sciences
Discovery of cellular snooze button advances cancer and biofuel research
The discovery of a cellular snooze button has allowed a team of Michigan State University scientists to potentially improve biofuel production and offer insight on the early stages of cancer.

Contact: Layne Cameron
Michigan State University

Public Release: 13-Oct-2014
Treating cancer: UI biologists find gene that could stop tumors in their tracks
UI researchers have found a gene in a soil amoeba that can overcompensate for the specific mutations of a similar gene. In humans, those genetic mutations can often lead to tumor growth. Researchers are now looking for a separate human gene that could overcompensate for mutations in the same way.
NIH/The Developmental Studies Hybridoma Bank

Contact: Brittany Borghi
University of Iowa

Public Release: 13-Oct-2014
Journal of Clinical Endocrinology and Metabolism
Cushing's syndrome: LCSB researchers characterize a new tumor syndrome
Scientists at the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg have published their findings that mutations in a gene known as 'ARMC5' promote the growth of benign tumors in the adrenal glands and on the meninges: ARMC5 appears to belong to the group of so-called tumor suppressor genes. It is the first time in years that scientists have characterized such a gene.

Contact: Britta Schlüter
University of Luxembourg

Public Release: 10-Oct-2014
Physics in Medicine and Biology
New technique enables increasingly accurate PET scan to detect cancer and heart conditions
A novel technique which reduces image degradation caused by respiratory motion during a PET scan was developed in a recent study at the University of Eastern Finland. The new technique is based on bioimpedance measurement and it allows for image reconstruction at a specific phase of the patient's breathing pattern. This, in turn, makes it possible to reduce image degradation caused by motion.

Contact: Tuomas Koivumäki
University of Eastern Finland

Public Release: 10-Oct-2014
An unexpected bonus
The STAT transcription factors are involved in the development of many forms of cancer. STAT3 is frequently activated in tumor cells, so drugs targeting STAT3 could be used in cancer therapy. However, STAT3 is also important in the development of the immune system. Dagmar Gotthardt and colleagues at the Vetmeduni Vienna now show that blocking STAT3 in cells of the immune system actually leads to increased anti-tumor immunity. Anti-STAT3 therapy may thus be highly promising.

Contact: Susanna Kautschitsch
University of Veterinary Medicine -- Vienna

Public Release: 10-Oct-2014
Clinical and Translational Gastroenterology
LSU Health tumor registry data find Acadiana colon cancer rates among nation's highest
A special study using data from LSU Health New Orleans School of Public Health's Louisiana Tumor Registry has found that colorectal cancer incidence rates in the Louisiana Acadian parishes are among the highest in the United States. This study appears to be the first to identify a high rate of cancer in a large, regional, US founder population, raising the possibility of a genetic predisposition. Alternatively, an unidentified, robust environmental risk factor may be present.
NIH/National Institute of Cancer, US Centers for Disease Control and Prevention

Contact: Leslie Capo
Louisiana State University Health Sciences Center

Public Release: 10-Oct-2014
CNIO researchers associate 2 oncogenes with the aggressiveness and incidence of leukemia in mice
Fighting oncogenes Cdk4 and Cdk6 with inhibitors that target both molecules is more effective than inhibiting them individually. These findings could have relevance in the further development of this group of drugs, which are already being tested successfully in breast cancer clinical trials.

Contact: Nuria Noriega
Centro Nacional de Investigaciones Oncologicas (CNIO)

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