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Showing releases 1176-1200 out of 1311.

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Public Release: 15-Dec-2014
Annals of Internal Medicine
News from Dec. 16, 2014 Annals of Internal Medicine
This issue of Annals of Internal Medicine includes: 'Earlier detection could close the race gap on colon cancer deaths'; 'Emphysema on CT an important independent risk factor for death'; and 'Patient feelings about consent for use of personal medical data: It's complicated.'

Contact: Megan Hanks
American College of Physicians

Public Release: 14-Dec-2014
Genes & Development
Baby cells learn to communicate using the Lsd1 gene
New research shows that infant cells have to go through a developmental process that involves specific genes before they can take part in the group interactions that underlie normal cellular development and keep our tissues functioning smoothly. The existence of a childhood state where cells cannot communicate fully has potentially important implications for our understanding of how gene activity on chromosomes changes both during normal development and in cancerous cells.
Howard Hughes Medical Institute

Contact: Allan Spradling
Carnegie Institution

Public Release: 12-Dec-2014
Journal of the National Cancer Institute
Migraine was not associated with BC in a pooled analysis of prospective cohort studies
Migraine was not associated with breast cancer risk or differences in the endogenous sex hormones that have been proposed to be associated with migraines, according to a new study published Dec. 12 in the JNCI: Journal of the National Cancer Institute.

Contact: Zachary Rathner
Oxford University Press USA

Public Release: 12-Dec-2014
2014 San Antonio Breast Cancer Symposium
Male and female breast cancers are not identical
Results of the EORTC10085/TBCRC/BIG/NABCG International Male Breast Cancer Program conducted in both Europe and in the United States and presented at the 2014 San Antonio Breast Cancer Symposium found significant improvement in survival for men with breast cancer, but this improvement was not as good as that observed for women. The study, which included 1822 men treated for breast cancer between 1990 and 2010, provides much needed information about the clinical and biological characteristics of male breast cancer.
Breast Cancer Research Foundation, European Organisation for Research and Treatment of Cancer Breast Cancer Group, Dutch Pink Ribbon, European Breast Cancer Conferences Council, Swedish Breast Cancer Association, Susan G. Komen For the Cure

Contact: John Bean
European Organisation for Research and Treatment of Cancer

Public Release: 12-Dec-2014
Proceedings of the National Academy of Sciences
MBL imaging technique reveals that bacterial biofilms are associated with colon cancer
An imaging technology developed at MBL reveals that bacterial biofilms are associated with colon cancer. Reported in PNAS with lead authors from Johns Hopkins Medical Institutions.
National Institutes of Health, Merieux Foundation

Contact: Diana Kenney
Marine Biological Laboratory

Public Release: 12-Dec-2014
Cell Reports
A control knob for fat?
Researchers found a new function for a long-studied gene: it appears to regulate fat storage in C. elegans.
NIH/National Institutes of Health, American Heart Association, The Ellison Medical Foundation, American Federation of Aging Research

Contact: Robert Perkins
University of Southern California

Public Release: 11-Dec-2014
Cancer Cell
New targeted drugs could treat drug-resistant skin cancer
A brand new family of cancer drugs designed to block several key cancer-causing proteins at once could potentially treat incurable skin cancers, a major new study reports. Clinical trials to test the new drugs in patients should begin as early as 2015.
Wellcome Trust, Cancer Research UK

Contact: Clare Ryan
Wellcome Trust

Public Release: 11-Dec-2014
Cancer Cell
Getting antibodies into shape to fight cancer
Scientists at the University of Southampton have found that the precise shape of an antibody makes a big difference to how it can stimulate the body's immune system to fight cancer, paving the way for much more effective treatments.
Cancer Research UK

Contact: Becky Attwood
University of Southampton

Public Release: 11-Dec-2014
San Antonio Breast Cancer Symposium
Lancet Oncology
New evidence reveals tamoxifen reduces breast cancer rates by nearly a third for 20 years
The preventive effect of breast cancer drug 'tamoxifen' remains virtually constant for at least 20 years -- with rates reduced by around 30 percent -- new analysis published in The Lancet Oncology reveals.
Cancer Research UK

Contact: Charli Scouller
Queen Mary, University of London

Public Release: 11-Dec-2014
Developmental Cell
Senescent cells play an essential role in wound healing
Tumor suppressing senescent cells are bad for aging. The no-longer-dividing cells release a continual cascade of inflammatory factors and are implicated in many maladies including arthritis, atherosclerosis and late life cancer. But researchers show that senescent cells are good for wound healing -- identifying a single factor that causes them to promote that process. It's a crucial discovery for researchers working on developing treatments to clear senescent cells as a way to stem age-related disease.
American Italian Cancer Foundation, Japan Science and Technology Agency, National Institutes of Health, European Council

Contact: Kris Rebillot
Buck Institute for Age Research

Public Release: 11-Dec-2014
San Antonio Breast Cancer Symposium
Three San Antonio studies target androgen in breast cancer
Three studies presented by University of Colorado Cancer Center researchers at the San Antonio Breast Cancer Symposium 2014 demonstrate the effects of blocking androgen receptors in breast cancer.

Contact: Garth Sundem
University of Colorado Denver

Public Release: 11-Dec-2014
Medical Care
Early adoption of robotic surgery leads to organ preservation for kidney cancer patients
Researchers at NYU Langone Medical Center conclude that patients with operable kidney tumors were more likely to undergo a partial nephrectomy -- the recommended course of treatment -- at hospitals that were early adopters of robotic surgery.

Contact: Jim Mandler
NYU Langone Medical Center / New York University School of Medicine

Public Release: 11-Dec-2014
American Journal of Epidemiology
Human exposure to metal cadmium may accelerate cellular aging
A new study led by a researcher at Milken Institute School of Public Health at the George Washington University looks at the metal cadmium and finds that higher human exposure can lead to significantly shorter telomeres, bits of DNA at the ends of chromosomes that are associated with cardiovascular disease, diabetes and other diseases of old age.

Contact: Kathy Fackelmann
George Washington University Milken Institute School of Public Health

Public Release: 11-Dec-2014
Medical Care
Surgical robot adopters use more of recommended procedure for kidney cancer, reports Medical Care
Hospitals with robotic surgical systems are more likely to perform 'nephron-sparing' partial nephrectomy -- a recommended alternative to removal of the entire kidney -- in patients with kidney cancer, reports a study in the December issue of Medical Care. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

Contact: Connie Hughes
Wolters Kluwer Health

Public Release: 11-Dec-2014
Journal of Biomedical Nanotechnology
'Trojan horse' proteins used to target hard-to-reach cancers
Scientists at Brunel University London have found a way of targeting hard-to-reach cancers and degenerative diseases using nanoparticles, but without causing the damaging side effects the treatment normally brings.

Contact: Keith Coles
Brunel University

Public Release: 11-Dec-2014
New discoveries in age-related macular degeneration revealed in industry and academia
Insilico Medicine along with scientists from Vision Genomics and Howard University shed light on AMD disease, introducing the opportunity for eventual diagnostic and treatment options.

Contact: Michael Petr
InSilico Medicine, Inc.

Public Release: 11-Dec-2014
Scientists define important gene interaction that drives aggressive brain cancer
Targeted therapies are a growing and groundbreaking field in cancer care in which drugs or other substances are designed to interfere with genes or molecules that control the growth and survival of cancer cells. Now, scientists at Virginia Commonwealth University Massey Cancer Center have identified a novel interaction between a microRNA and a gene that could lead to new therapies for the most common and deadly form of brain tumor, malignant glioma.

Contact: John Wallace
Virginia Commonwealth University

Public Release: 11-Dec-2014
Molecular Cell
MSU scientists find way to boost healthy cells during chemo
Michigan State University scientists are closer to discovering a possible way to boost healthy cell production in cancer patients as they receive chemotherapy. By adding thymine -- a natural building block found in DNA -- into normal cells, they found it stimulated gene production and caused them to multiply.
US Department of Defense, NIH/National Cancer Institute

Contact: Sarina Gleason
Michigan State University

Public Release: 11-Dec-2014
Journal of Clinical Oncology
Youngest bone marrow transplant patients at higher risk of cognitive decline
Toddlers who undergo total body irradiation in preparation for bone marrow transplantation are at higher risk for a decline in IQ and may be candidates for stepped up interventions to preserve intellectual functioning, St. Jude Children's Research Hospital investigators reported. The findings appear in the current issue of the Journal of Clinical Oncology.
National Institutes of Health, ALSAC

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Public Release: 11-Dec-2014
WPI team develops tool to better classify tumor cells for personalized cancer treatments
A new statistical model developed by a research team at Worcester Polytechnic Institute may enable physicians to create personalized cancer treatments for patients based on the specific genetic mutations found in their tumors. The model uses an advanced algorithm to identify the multiple genetic cell subtypes typically found in solid tumors by analyzing gene expression data from a small biopsy sample. The results can help shape more effective treatments and also guide future research.

Contact: Michael Cohen
Worcester Polytechnic Institute

Public Release: 11-Dec-2014
3-D maps reveal the genome's origami code
In a triumph for cell biology, researchers have assembled the first high-resolution, 3-D maps of entire folded genomes and found a structural basis for gene regulation -- a kind of 'genomic origami' that allows the same genome to produce different types of cells. The research appears online today in Cell.
National Science Foundation, National Institutes of Health, NIH/National Human Genome Research Institute, NVIDIA, IBM, Google, Cancer Prevention and Research Institute of Texas, McNair Medical Institute

Contact: Jade Boyd
Rice University

Public Release: 10-Dec-2014
2014 San Antonio Breast Cancer Symposium
New drug combination for advanced breast cancer delays disease progression
A new combination of cancer drugs delayed disease progression for patients with hormone-receptor-positive metastatic breast cancer, according to a multi-center phase II trial. The findings of the randomized study were presented at the 2014 San Antonio Breast Cancer Symposium, held Dec. 6-9, by Kerin Adelson, M.D., assistant professor of medical oncology at Yale Cancer Center and chief quality officer at Smilow Cancer Hospital at Yale-New Haven.
NIH/National Cancer Institute, Millenium, Takeda Oncology Company

Contact: Vicky Agnew
Yale University

Public Release: 10-Dec-2014
Journal of Cardiac Failure
NYIT study: Thyroid hormones reduce animal cardiac arrhythmias
Rats that received thyroid hormones had a reduced risk for dangerous heart arrhythmias following a heart attack, according to a new study by a team of medical researchers at New York Institute of Technology. In the National Institutes of Health-funded study, published in the Journal of Cardiac Failure, the team found that thyroid hormone replacement therapy significantly reduced the incidence of atrial fibrillation -- a specific kind of irregular heartbeat, or arrhythmia -- in the rats, compared to a control group that did not receive the hormones.
National Institutes of Health

Contact: Elaine Iandoli
New York Institute of Technology

Public Release: 10-Dec-2014
2014 San Antonio Breast Cancer Symposium
Novel approach for estrogen-receptor-positive breast cancer reported
Loyola researchers and collaborators have reported promising results from a novel therapeutic approach for women with estrogen-receptor-positive breast cancer.

Contact: Nora Dudley
Loyola University Health System

Public Release: 10-Dec-2014
Chemical Research in Toxicology
New technology tracks carcinogens as they move through the body
Researchers for the first time have developed a method to track through the human body the movement of polycyclic aromatic hydrocarbons as extraordinarily tiny amounts of these potential carcinogens are biologically processed and eliminated.
Public Health Service, US Department of Energy, NIH/National Institute of General Medical Sciences

Contact: David Williams
Oregon State University

Showing releases 1176-1200 out of 1311.

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