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Showing releases 1176-1200 out of 1292.

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Public Release: 18-Nov-2015
Clinical Cancer Research
Investigational immunotherapeutic increased bladder cancer survival
Among patients with metastatic bladder cancer that had progressed after platinum-based chemotherapy, those who received an investigational, personalized peptide cancer vaccine and best-supportive care had extended overall survival compared with those who received best-supportive care alone, according to results from a randomized, phase II clinical.
Ministry of Education, Science, Sports, and Culture in Japan

Contact: Lauren Riley
lauren.riley@aacr.org
215-446-7155
American Association for Cancer Research

Public Release: 18-Nov-2015
PLOS ONE
One very brainy bird
A joint study by the University of Iowa and University of California-Davis found pigeons performed as well as humans in categorizing digitized slides and mammograms of benign and malignant human breast tissue. Results published in the journal PLOS ONE.
National Institutes of Health

Contact: Richard Lewis
richard-c-lewis@uiowa.edu
319-384-0012
University of Iowa

Public Release: 18-Nov-2015
Cancer Epidemiology, Biomarkers & Prevention
Higher nicotine, carcinogen levels among smokeless tobacco users compared with cig users
U.S. adults who used only smokeless tobacco products had higher levels of biomarkers of exposure to nicotine and a cancer-causing toxicant -- the tobacco-specific nitrosamine NNK -- compared with those who used only cigarettes.
U.S. Food and Drug Administration, Centers for Disease Control and Prevention

Contact: Lauren Riley
lauren.riley@aacr.org
215-446-7155
American Association for Cancer Research

Public Release: 18-Nov-2015
Biotechnology Journal
Chemical engineers have figured out how to make vaccines faster
Researchers at Brigham Young University have devised a system to speed up the process of making life-saving vaccines for new viruses. Their concept is to create the biological machinery for vaccine production en masse, put it in a freeze-dried state and stockpile it around the country. Then, when a new virus hits, labs can simply add water to a 'kit' to rapidly produce vaccines.
National Science Foundation, Defense Advanced Research Projects Agency

Contact: Todd Hollingshead
toddh@byu.edu
801-422-8373
Brigham Young University

Public Release: 18-Nov-2015
PLOS ONE
Common pigeon: Not just a bird brain, but a brainy bird
A new study has found that pigeons are very good at distinguishing digitized microscope slides and mammograms of normal vs. cancerous breast tissue. With training and selective food reinforcement, pigeons were remarkably adept at identifying benign and malignant breast cancer slides at all magnification levels, a task that typically requires considerable training for humans to master. They also successfully identified microcalcifications on mammograms but had difficulty with classifying breast masses, a very challenging task even for humans.
National Institutes of Health

Contact: Carole Gan
cfgan@ucdavis.edu
916-734-9047
University of California - Davis Health System

Public Release: 18-Nov-2015
Science Translational Medicine
New method developed to predict response to nanotherapeutics
A collaboration between investigators at Massachusetts General Hospital and Brigham and Women's Hospital has led to a new approach that uses an FDA-approved, magnetic nanoparticle and magnetic resonance imaging to identify tumors most likely to respond to drugs delivered via nanoparticles. The team's preclinical results are published in Science Translational Medicine Nov. 18.
National Institutes of Health, David H. Koch-Prostate Cancer Foundation Award in Nanotherapeutics

Contact: Haley Bridger
hbridger@partners.org
978-807-5302
Brigham and Women's Hospital

Public Release: 18-Nov-2015
Seminars in Cancer Biology
Global task force tackles problem of untreatable cancers and disease relapse 
Combinations of a significant number of non-toxic substances, many of which can be found in plants and foods, may give us a chance to stop untreatable cancers and prevent disease.

Contact: Leroy Lowe
leroy.lowe@gettingtoknowcancer.org
902-893-5362
Saarland University

Public Release: 18-Nov-2015
Science Translational Medicine
Wisconsin scientists grow functional vocal cord tissue in the lab
University of Wisconsin-Madison scientists have succeeded in growing functional vocal cord tissue in the laboratory, a major step toward restoring a voice to people who have lost their vocal cords to cancer surgery or other injuries. Dr. Nathan Welham, a UW speech-language pathologist, and colleagues from several disciplines were able to bioengineer vocal cord tissue able to transmit sound, they reported in a study published today in the journal Science Translational Medicine.
NIH/National Institute on Deafness and Other Communication Disorders, NIH/National Institute of Allergy and Infectious Diseases

Contact: Susan Lampert Smith
ssmith5@uwhealth.org
608-890-5643
University of Wisconsin-Madison

Public Release: 18-Nov-2015
Proceedings of the National Academy of Sciences
Mutations in key cancer protein suggest new route to treatments
Researchers found they could disrupt STAT3's ability to act as a transcription factor by altering part of the protein, which interfered with its cancer-promoting activity. The findings suggest a basis for new, targeted approaches to fighting cancer.

Contact: Katherine Fenz
kfenz@rockefeller.edu
212-327-7913
Rockefeller University

Public Release: 18-Nov-2015
Scientific Reports
Technique to more effectively diagnose and treat cancer developed by Georgia State University
A method to better trace changes in cancers and treatment of the prostate and lung without the limitations associated with radiation has been developed by Georgia State University researchers.

Contact: Brian Mullen
bmullen@gsu.edu
404-413-5464
Georgia State University

Public Release: 18-Nov-2015
Breast Cancer Research and Treatment
Without prescription coverage, some cancer patients do without even low-cost drugs
A University of Colorado Cancer Center study published in the journal Breast Cancer Research and Treatment shows that breast cancer patients whose health insurance plans included prescription drug benefits were 10 percent more likely to start important hormonal therapy than patients who did not have prescription drug coverage. Women with household income below $40,000 were less than half as likely as women with annual household income greater than $70,000 to continue hormonal therapy.
National Institutes of Health, NIH/National Cancer Institute

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Anschutz Medical Campus

Public Release: 18-Nov-2015
International Society of Neurogastronomy Symposium
Neurogastronomy: How our brains perceive the flavor of food
Neuroscientists, food scientists and internationally renowned chefs convened at the University of Kentucky recently to explore ways to help patients with neurologically related taste impairments enjoy food again.

Contact: Laura Dawahare
Laura.Dawahare@uky.edu
859-257-5307
University of Kentucky

Public Release: 18-Nov-2015
Lancet Haematology
Late effects of treatment study continues sustained academic effort in Hodgkin's lymphoma
'These study results are exciting. They should allow physicians to optimize the combination of systemic therapy and radiation and thereby balance the risks and benefits of different regimens in individual patients.'

Contact: John Bean
john.bean@eortc.be
European Organisation for Research and Treatment of Cancer

Public Release: 18-Nov-2015
Seminars in Cancer Biology
Plant and food-based compounds may be key to future cancer prevention
Rather than targeting one or two specific genes or proteins that contribute to cancer, the task force was charged with researching a broad-spectrum approach. 'This type of approach involves combinations of multiple low-toxicity agents that can collectively impact many pathways that are known to be important for the genesis and spread of cancer,' said Kumar.
Getting to Know Cancer

Contact: Steven Blanchard
steve.blanchard@moffitt.org
813-745-1718
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 18-Nov-2015
New England Journal of Medicine
Why do children develop cancer?
As new scientific discoveries deepen our understanding of how cancer develops in children, doctors and other healthcare providers face challenges in better using that knowledge to guide treatment and counsel families and patients. A CHOP pediatric oncologist offers expert commentary on a major study of cancer predisposition genes in children being published today, and outlines areas for further investigation.

Contact: John Ascenzi
Ascenzi@email.chop.edu
267-426-6055
Children's Hospital of Philadelphia

Public Release: 17-Nov-2015
JAMA
Prostate cancer screening drops dramatically in middle-aged men
PSA testing has dropped significantly in middle-aged men after a 2012 recommendation that all men should not be routinely screened for prostate cancer, according to a new study published in the Journal of the American Medical Association.

Contact: Johanna Younghans
jyounghans@partners.org
617-525-6375
Brigham and Women's Hospital

Public Release: 17-Nov-2015
JAMA
Studies find decline in rates of PSA screening, early-stage prostate cancer
Two studies in the Nov. 17 issue of JAMA examine the change in prostate-specific antigen screening and prostate cancer incidence before and after the 2012 US Preventive Services Task Force screening recommendations.

Contact: David Sampson
david.sampson@cancer.org
The JAMA Network Journals

Public Release: 17-Nov-2015
Scientific Reports
Metabolic profiles distinguish early stage ovarian cancer with unprecedented accuracy
Studying blood serum compounds of different molecular weights has led scientists to a set of biomarkers that may enable development of a highly accurate screening test for early-stage ovarian cancer.

Contact: John Toon
jtoon@gatech.edu
404-894-6986
Georgia Institute of Technology

Public Release: 17-Nov-2015
Science Signaling
Researchers identify a new mode of drug resistance to emerging therapies in prostate cancer
Advanced prostate cancer is a disease notoriously resistant to treatment. New research by scientists at Fred Hutchinson Cancer Research Center and the University of California, San Francisco sheds light on a new mode of drug resistance to emerging therapies in metastatic prostate cancer. This discovery ultimately may help predict which patients may benefit most from treatment.
Burroughs Wellcome Fund Career Award for Medical Scientists, Prostate Cancer Foundation, National Institutes of Health, V Foundation, Stand Up to Cancer, Movember Foundation

Contact: Kristen Woodward
kwoodwar@fredhutch.org
206-667-5095
Fred Hutchinson Cancer Research Center

Public Release: 17-Nov-2015
Gastroenterology
Study advances potential test to sort out precancerous pancreatic cysts from harmless ones
In a 'look-back' analysis of data stored on 130 patients with pancreatic cysts, scientists at Johns Hopkins have used gene-based tests and a fixed set of clinical criteria to more accurately distinguish precancerous cysts from those less likely to do harm.
Lustgarten Foundation for Pancreatic Cancer Research, Sol Goldman Center for Pancreatic Cancer Research, Virginia and D.K. Ludwig Fund for Cancer Research, Susan Wojcicki and Dennis Troper, Michael Rolfe Foundation, and others

Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medicine

Public Release: 17-Nov-2015
Working up a sweat may protect men from lethal prostate cancer
A study that tracked tens of thousands of midlife and older men for more than 20 years has found that vigorous exercise and other healthy lifestyle habits may cut their chances of developing a lethal type of prostate cancer by up to 68 percent.

Contact: Suzanne Leigh
Suzanne.Leigh@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 17-Nov-2015
ACS Nano
Nanotech-based sensor developed to measure microRNAs in blood, speed cancer detection
A simple, ultrasensitive microRNA sensor developed and tested by researchers from the schools of science and medicine at Indiana University-Purdue University Indianapolis and the Indiana University Melvin and Bren Simon Cancer Center holds promise for the design of new diagnostic strategies and, potentially, for the prognosis and treatment of pancreatic and other cancers.
Indiana University-Purdue University Indianapolis, Indiana University, NIH/National Cancer Institute

Contact: Cindy Fox Aisen
caisen@iupui.edu
317-843-2276
Indiana University-Purdue University Indianapolis School of Science

Public Release: 17-Nov-2015
PLOS ONE
Scientists find bone protein inhibits prostate cancer invasion
Scientists from Lawrence Livermore National Laboratory in collaboration with researchers from University of California campuses at Merced and Davis have found that a secreted protein predominantly expressed in bone inhibits prostate cancer metastasis to bone.

Contact: Anne Stark
stark8@llnl.gov
925-422-9799
DOE/Lawrence Livermore National Laboratory

Public Release: 17-Nov-2015
Oncotarget
Nondrug interventions improve quality of life for Chinese cancer patients
A meta-analysis of dozens of studies of traditional Chinese medicine and other nonpharmacological interventions meant to improve patients' quality of life affirms that these approaches, on the whole, help alleviate depression, fatigue, pain, anxiety, insomnia and gastrointestinal problems in Chinese cancer patients.
National Institutes of Health, National Science Foundation of China, National Basic Research Program of China

Contact: Diana Yates
diya@illinois.edu
217-333-5802
University of Illinois at Urbana-Champaign

Public Release: 16-Nov-2015
Cancer Research
Researchers find experimental drug can help fight debilitating side effect of ovarian cancer
UCLA researchers have found that a drug that inhibits a receptor called the Colony-Stimulating-Factor-1 Receptor, or CSF1R, reduces ascites with minimal side effects.

Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-794-2262
University of California - Los Angeles Health Sciences

Showing releases 1176-1200 out of 1292.

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