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Showing releases 1176-1200 out of 1332.

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Public Release: 14-Nov-2014
Cancer Epidemiology, Biomarkers & Prevention
Nonsmokers in automobiles are exposed to significant secondhand smoke
Nonsmokers sitting in an automobile with a smoker for one hour had markers of significantly increased levels of carcinogens and other toxins in their urine, indicating that secondhand smoke in motor vehicles poses a potentially major health risk according to a groundbreaking study led by University of California San Francisco researchers.
Flight Attendants Medical Research Institute, US Public Health Service, National Institutes of Health

Contact: Elizabeth Fernandez
University of California - San Francisco

Public Release: 14-Nov-2014
Cancer Research
New imaging technique identifies receptors for targeted cancer therapy
Dartmouth researchers have developed a fluorescence imaging technique that can more accurately identify receptors for targeted cancer therapies without a tissue biopsy. They report on their findings in 'Quantitative in vivo immunohistochemistry of epidermal growth factor receptor using a receptor concentration imaging approach,' which was recently published in Cancer Research.
National Institutes of Health

Contact: Robin Dutcher
The Geisel School of Medicine at Dartmouth

Public Release: 14-Nov-2014
Cancer Research
Scientists uncover vast numbers of DNA 'blind spots' that may hide cancer-causing mistakes
Cancer Research UK scientists have found more than 400 'blind spots' in DNA which could hide cancer-causing gene faults, according to research published Friday, Nov. 14, in Cancer Research.
Cancer Research UK

Contact: Emily Head
Cancer Research UK

Public Release: 14-Nov-2014
Molecular Cancer Therapeutics
Killing cancer by protecting normal cells
An anti-cancer drug protects normal cells from radiation damage and increases the effectiveness of radiation therapy in prostate cancer models.

Contact: Edyta Zielinska
Thomas Jefferson University

Public Release: 14-Nov-2014
Nature Scientific Reports
Cutting-edge computer software helps pinpoint aggressiveness of breast cancer tumors
Researchers at Western University are using cutting-edge genetic mutation-analysis software developed in their lab to interpret mutations in tumor genome that may provide insight into determining which breast cancer tumors are more likely spread to other parts of the body and which ones won't.

Contact: Crystal Mackay
519-661-2111 x80387
University of Western Ontario

Public Release: 14-Nov-2014
European Urology
Conventional therapies are less efficient in prostate cancer patients carrying 'BRCA' mutations
Monitoring of over 1,300 patients reveals that the 10-year survival rates for BRCA mutation carriers who undergo radiation therapy are half those for non-carriers. The conclusions recommend a closer monitoring of patients who are carriers of the mutation and the development of clinical trials that specifically target these mutations.

Contact: Nuria Noriega
Centro Nacional de Investigaciones Oncologicas (CNIO)

Public Release: 14-Nov-2014
Histology and Histopathology
Expression of SIP1 protein indicates poor prognosis in pharyngeal cancer
The expression of SIP1 protein in pharyngeal squamous cell carcinoma tumours often indicates an advanced tumour stage, a high risk of recurrence and a poor prognosis, according to research from the University of Eastern Finland. Based on the results, SIP1 is a potential new prognostic factor for clinical use, helping to single out patients with more aggressive tumor behavior requiring more intensive therapy and closer follow-up.

Contact: Anna Jouppila-Mättö
University of Eastern Finland

Public Release: 13-Nov-2014
EMBO Molecular Medicine
Scientists develop scoring scheme that predicts ability of cancer cells to spread
Scientists at the Cancer Science Institute of Singapore at the National University of Singapore and their collaborators have developed a scoring scheme that predicts the ability of cancer cells to spread to other parts of the body, a process known as metastasis. This system, which is the first of its kind, opens up the possibility to explore new treatments that suppress metastasis in cancer patients.

Contact: Kimberley Wang
National University of Singapore

Public Release: 13-Nov-2014
BMJ Open
Britain's obese in denial about their weight
A majority of obese people in Britain would not describe themselves as 'obese,' and many would not even describe themselves as 'very overweight,' according to a Cancer Research UK study published in BMJ Open Friday.
Cancer Research UK

Contact: Stephanie McClellan
Cancer Research UK

Public Release: 13-Nov-2014
Hedgehog signaling pathway for breast cancer identified
Molecules called long non-coding RNAs -- lncRNAs -- have been implicated in breast cancer but exactly why they cause metastasis and tumor growth has been little understood... until now.

Contact: Ron Gilmore
University of Texas M. D. Anderson Cancer Center

Public Release: 13-Nov-2014
Cancer Immunology, Immunotherapy
Novel cancer vaccine approach for brain tumors
Researchers unravel the mechanisms behind a novel cancer vaccine for brain tumors, paving the way for further development.

Contact: Edyta Zielinska
Thomas Jefferson University

Public Release: 13-Nov-2014
Cancer Cell
How the breast cancer cells transform normal cells into tumoral ones?
Researchers at the Bellvitge Biomedical Research Institute of Bellvitge, the Catalan Institute of Oncology and the University Hospital of Bellvitge have participated in an international study published in the journal Cancer Cell that describes how exosomes secreted by tumor cells contain protein and microRNA molecules capable of transform neighboring cells into tumoral cells promoting tumor growth.

Contact: Arantxa Mena
IDIBELL-Bellvitge Biomedical Research Institute

Public Release: 13-Nov-2014
Cell Stem Cell
Tumor suppressor also inhibits key property of stem cells, Stanford researchers say
A protein that plays a critical role in preventing the development of many types of human cancers has been shown also to inhibit a vital stem cell property called pluripotency, according to a study by researchers at the Stanford University School of Medicine.
NIH/National Cancer Institute, Spectrum Child Health, Lucile Packard Foundation for Children's Health, California Institute for Regenerative Medicine New York Stem Cell Foundation

Contact: Krista Conger
Stanford University Medical Center

Public Release: 13-Nov-2014
Direct drug screening of patient biopsies could overcome resistance to targeted therapy
A new screening platform using cells grown directly from tumor biopsy samples may lead to truly individualized treatment strategies that would get around the problem of treatment resistance, which limits the effectiveness of current targeted therapy drugs.
National Institutes of Health, Wellcome Trust, Department of Defense, Conquer CNational Institutes of Health, Wellcome Trust, US Department of Defense, Coancer Foundation, Uniting Against Lung Cancer, Free to Breathe, Lungevity, Be a Piece of the Solution

Contact: Katie Marquedant
Massachusetts General Hospital

Public Release: 13-Nov-2014
Molecule fights cancer on 2 fronts
Researchers at the University of Leeds have made a new synthetic anti-cancer molecule that targets two key mechanisms in the spread of malignant tumors through the body.
Biotechnology and Biological Sciences Research Council, Pfizer Global Inc., Medical Research Council, British Heart Foundation

Contact: Press Office
University of Leeds

Public Release: 13-Nov-2014
Cell Reports
IU researchers identify key mechanism and potential target to prevent leukemia
Researchers have identified two proteins that appear crucial to the development -- and patient relapse -- of acute myeloid leukemia. They have also shown they can block the development of leukemia by targeting those proteins.
National Institutes of Health, Riley Children's Foundation, American Cancer Society

Contact: Eric Schoch
Indiana University

Public Release: 13-Nov-2014
Journal of Medicinal Food
'Tis the season to indulge in walnuts
Researchers at UC Davis and other institutions have found that diets rich in whole walnuts or walnut oil slowed prostate cancer growth in mice. In addition, both walnuts and walnut oil reduced cholesterol and increased insulin sensitivity.
American Institute for Cancer Research, California Walnut Board, KU-Research Professor Program of Konkuk University

Contact: Dorsey Griffith
University of California - Davis Health System

Public Release: 13-Nov-2014
Clinical Cancer Research
Cancer-killing virus plus chemotherapy drug might treat recurrent ovarian cancer
In six out of 10 cases, ovarian cancer is diagnosed when the disease is advanced and five-year survival is only 27 percent. A new study suggests that a cancer-killing virus combined with a chemotherapy drug might safely and effectively treat advanced or recurrent forms of the disease.
NIH/National Cancer Institute

Contact: Darrell E. Ward
Ohio State University Wexner Medical Center

Public Release: 13-Nov-2014
FASEB Journal
U of G scientists find way to reduce ovarian cancer tumors, chemo doses
In a potential breakthrough against ovarian cancer, University of Guelph researchers have discovered how to both shrink tumours and improve drug delivery, allowing for lower doses of chemotherapy and reducing side effects.
Canadian Institutes for Health Research, Ovarian Cancer Canada, National Institutes of Health, Beth Israel Deaconess Medical Center

Contact: Jim Petrik
519-824-4120 x54921
University of Guelph

Public Release: 13-Nov-2014
Journal of the American Geriatrics Society
Nonclinical factors may affect whether intensive procedures are used at the end of life
In a study that looked at what factors might affect whether or not a patient receives intensive medical procedures in the last 6 months of life, investigators found that older age, Alzheimer's disease, cancer, living in a nursing home, and having an advance directive were associated with a lower likelihood of undergoing an intensive procedure. In contrast, living in a region with higher hospital care intensity and black race each doubled a patient's likelihood of undergoing an intensive procedure.

Contact: Dawn Peters

Public Release: 13-Nov-2014
Journal of National Cancer Institute
Genetic testing could improve breast cancer prevention
Screening women for a wide range of known genetic risk factors could improve strategies for breast cancer prevention, a new analysis shows.

Contact: Amy Drummond
Institute of Cancer Research

Public Release: 13-Nov-2014
Molecular Cancer Therapeutics
UNC researchers silence leading cancer-causing gene
Researchers have developed a new approach to block the KRAS oncogene, one of the most frequently mutated genes in human cancer. The approach offers another route to attack KRAS, which has proven to be an elusive and frustrating target for drug developers.
National Institutes of Health

Contact: Mark Derewicz
University of North Carolina Health Care

Public Release: 12-Nov-2014
Cancer Research
Innovative approach to treating pancreatic cancer combines chemo- and immuno-therapy
VCU Massey Cancer Center and VCU Institute of Molecular Medicine researchers discovered a unique approach to treating pancreatic cancer that may be potentially safe and effective.
NIH/National Cancer Institute

Contact: John Wallace
Virginia Commonwealth University

Public Release: 12-Nov-2014
Cancer Discovery
Gene sequencing projects link two mutations to Ewing sarcoma subtype with poor prognosis
An international collaboration has identified frequent mutations in two genes that often occur together in Ewing sarcoma and that define a subtype of the cancer associated with reduced survival. The research, conducted by the St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project and the Institut Curie-Inserm through the International Cancer Genome Consortium, appears in the current issue of the scientific journal Cancer Discovery.
Pediatric Cancer Genome Project, Kay Jewelers, NIH/National Cancer Institute, National Institutes of Health, French National Cancer Institute, Inserm, National Research Agency for Science Projects, Canceropole Ile-de-France, French League Against Cancer

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Public Release: 12-Nov-2014
Lancet Oncology
Prostate cancer researchers develop personalized genetic test to predict recurrence risk
Prostate cancer researchers have developed a genetic test to identify which men are at highest risk for their prostate cancer to come back after localized treatment with surgery or radiotherapy.
Prostate Cancer Canada, The Movember Foundation, Ontario Institute for Cancer Research, The Princess Margaret Cancer Foundation, Wellcome Trust Clinical Research Facility

Contact: Jane Finlayson
University Health Network

Showing releases 1176-1200 out of 1332.

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