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Showing releases 1201-1225 out of 1384.

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Public Release: 23-Mar-2016
Scientific Reports
Brad Pitt's and fruit flies' cowlicks controlled by cancer protein
What does Brad Pitt have in common with a fruit fly? His Hollywood hairstyles cover a prominent cowlick -- the swirl of hair that that is caused by a patterning mechanism also active in our two-winged friends -- that similarly feature 'polarized' hair patterns.
National Institutes of Health

Contact: Layne Cameron
layne.cameron@cabs.msu.edu
517-353-8819
Michigan State University

Public Release: 23-Mar-2016
Nature Communications
Decreased blood vessel leakage can improve cancer therapy and reduce tumor spread
Cancer therapy is often hampered by the accumulation of fluids in and around the tumor, which is caused by leakage from the blood vessels in the tumor. Researchers at Uppsala University now show how leakage from blood vessels is regulated. They have identified a novel mechanism whereby leakage can be suppressed to improve the result of chemotherapy and reduce the spread of tumors in mice. The results have been published in the scientific journal Nature Communications.

Contact: Lena Claesson-Welsh
lena.welsh@igp.uu.se
46-701-679-260
Uppsala University

Public Release: 23-Mar-2016
New England Journal of Medicine
New imaging scans track down persistent cancer cells
Head and neck cancer patients may no longer have to undergo invasive post-treatment surgery to remove remaining cancer cells, as research shows that innovative scanning-led surveillance can help identify the need for, and guidance of, neck dissection.

Contact: Luke Harrison
l.harrison.1@bham.ac.uk
University of Birmingham

Public Release: 23-Mar-2016
PLOS ONE
New proteins discovered that link obesity-driven diabetes to cancer
For the first time, researchers have determined how bromodomain (BRD) proteins work in type 2 diabetes, which may lead to a better understanding of the link between adult-onset diabetes and certain cancers.
NIH/National Cancer Institute

Contact: Gina DiGravio
ginad@bu.edu
617-638-8480
Boston University Medical Center

Public Release: 23-Mar-2016
Nature
VIB, KU Leuven and UGent achieve breakthrough in diagnosis of melanoma skin cancer
In collaboration with researchers from UGent, VIB scientists from KU Leuven have revealed a remarkable link between malignant melanoma and a non-coding RNA gene called SAMMSON. The SAMMSON gene is expressed in human malignant melanoma and, strikingly, the growth of aggressive skin cancer is highly dependent on this gene. The conclusions could pave the way for improved diagnostic tools and skin cancer treatment.

Contact: Sooike Stoops
sooike.stoops@vib.be
32-924-46611
VIB (the Flanders Institute for Biotechnology)

Public Release: 22-Mar-2016
Journal of Biological Chemistry
Lymphoma overrides a key protein's quadruple locks
Protein chemists at Johns Hopkins report they are closer to explaining why certain blood cancers are able to crack a molecular security system and run rampant.
NIH/National Cancer Institute, Johns Hopkins University Institute for Cell Engineering, Leukemia and Lymphoma Society

Contact: Catherine Gara
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine

Public Release: 22-Mar-2016
JAMA
Drug combination reduces polyps for patients with high risk for colorectal cancer
In a study appearing in the March 22/29 issue of JAMA, Deborah W. Neklason, Ph.D., N. Jewel Samadder, M.D., M.S., of the Huntsman Cancer Institute, University of Utah, Salt Lake City, and colleagues randomly assigned 92 patients with familial adenomatous polyposis to the drugs sulindac twice daily and erlotinib daily (n = 46) or placebo (n = 46) for 6 months.

Contact: Linda Aagard
Linda.Aagard@hci.utah.edu
801-587-7639
The JAMA Network Journals

Public Release: 22-Mar-2016
JAMA
New treatment reduces precancerous polyps in hereditary cancer patients
Inheriting a mutation in the APC gene leads to a nearly 100 percent lifetime risk of colorectal cancer. A new study published in the Journal of the American Medical Association, has identified the first prevention treatment for these patients, a two-drug combination that significantly reduces the number and size of precancerous polyps in the small intestine.
NIH/National Cancer institute, Huntsman Cancer Institute, Huntsman Cancer Foundation, American College of Gastroenterology, National Institutes of Health

Contact: Linda Aagard
linda.aagard@hci.utah.edu
801-587-7639
University of Utah Health Sciences

Public Release: 22-Mar-2016
Mount Sinai first hospital to treat liver cancer with radiopaque bead
The M1 LUMI™ Bead provides visible confirmation during embolization treatment for liver cancer.

Contact: Lucia Lee
newsmedia@mssm.edu
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 22-Mar-2016
CA: A Cancer Journal for Clinicians
New guideline addresses long-term needs of head and neck cancer survivors
A new American Cancer Society guideline provides clinicians with recommendations on key areas of clinical follow-up care for survivors of head and neck cancer.
Centers for Disease Control and Prevention

Contact: David Sampson
david.sampson@cancer.org
American Cancer Society

Public Release: 22-Mar-2016
Cancer Research
Many targeted cancer therapies suppress T cell immune responses
New research from The Wistar Institute demonstrated that dozens of these targeted therapies suppressed the activity of T cells that could actually help fight tumors. While studying the FDA-approved targeted therapy trametinib, the researchers also found that pairing it with a signaling protein 'superagonist' stimulated T cell activity while preserving the cancer-blocking effects of the cancer treatment.
National Institutes of Health, Jayne Koskinas Ted Giovanis Foundation Breast Cancer Research Consortium, Ovarian Cancer Research Fund

Contact: Ben Leach
bleach@wistar.org
215-495-6800
The Wistar Institute

Public Release: 22-Mar-2016
Journal of Hepatology
More cost-effective cure for hepatitis C may be close
The cost of treating hepatitis C virus could be cut up to 50 percent if mathematical models are used to predict when patients can safely stop taking direct-acting antiviral medication, according to a new study by researchers at Loyola University Health System and Loyola University Chicago.

Contact: Stasia Thompson
thompson539@att.net
708-543-7377
Loyola University Health System

Public Release: 22-Mar-2016
Journal of Drug Targeting
Scientists distinguish molecules most capable of fighting prostate cancer
Scientists from MIPT (Moscow Institute of Physics and Technology), MSU (Moscow State University), and National University of Science and Technology 'MISIS' provided an overview of the most promising compounds which can be used as medications for prostate cancer. The article was published in the Journal of Drug Targeting.

Contact: Valerii Roizen
press@mipt.ru
7-929-992-2721
Moscow Institute of Physics and Technology

Public Release: 22-Mar-2016
Journal of Internal Medicine
Why do sunbathers live longer than those who avoid the sun?
New research looks into the paradox that women who sunbathe are likely to live longer than those who avoid the sun, even though sunbathers are at an increased risk of developing skin cancer.

Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley

Public Release: 21-Mar-2016
Proceedings of the National Academy of Sciences
Nanoparticle-based cancer therapies shown to work in humans
A team of researchers led by Caltech scientists have shown that nanoparticles can function to target tumors while avoiding adjacent healthy tissue in human cancer patients. The findings demonstrate that nanoparticle-based therapies can act as a 'precision medicine' for targeting tumors while leaving healthy tissue intact.
NIH/National Cancer Institute, National Institutes of Health, Cerulean Pharma Inc.

Contact: Deborah Williams-Hedges
debwms@caltech.edu
626-395-3227
California Institute of Technology

Public Release: 21-Mar-2016
Journal of Clinical Oncology
Racial, socioeconomic disparities in genomic test used in early-stage breast cancer
A University of Colorado Cancer Center study published today in the Journal of Clinical Oncology shows that African American patients are significantly less likely to receive a common test that predicts the seriousness of early-stage, estrogen-receptor-positive breast cancer.

Contact: Erika Matich
erika.matich@ucdenver.edu
University of Colorado Anschutz Medical Campus

Public Release: 21-Mar-2016
JAMA Pediatrics
Review and view of future in cancer in adolescents, young adults
A narrative review published online by JAMA Pediatrics examines the current status of cancer in adolescents and young adults and offers a view of the future.

Contact: Ronald D. Barr
rbarr@mcmaster.ca
The JAMA Network Journals

Public Release: 21-Mar-2016
Cytoskeleton
New way to treat cancer and vessel diseases
Cell biologists from the Lomonosov Moscow State University discovered a new way of regulating of cell motility -- this discovery will make possible development of new drugs for curing onco- and vessel diseases.

Contact: Vladimir Koryagin
science-release@rector.msu.ru
Lomonosov Moscow State University

Public Release: 21-Mar-2016
International Journal of Radiation Oncology, Biology, Physics
Travel burden linked with likelihood of receiving radiation therapy to treat rectal cancer
Increased travel distance to a cancer treatment facility negatively impacts the likelihood that patients with stage II/III rectal cancer will receive radiation therapy (RT) to treat their disease, according to a study analyzing 26,845 patient records from the National Cancer Data Base (NCDB) that was published in the March 2016 issue of International Journal of Radiation Oncology * Biology * Physics (Red Journal), the official scientific journal of the American Society for Radiation Oncology (ASTRO).

Contact: Liz Gardner
liz.gardner@astro.org
703-286-1600
American Society for Radiation Oncology

Public Release: 21-Mar-2016
PLOS ONE
Free pap screening did not increase participation
1,562 women were offered free gynecological pap test screening in three socioeconomically disadvantaged areas in Gothenburg, in 2013. A new study from Sahlgrenska Academy, Narhalsan and the Regional Cancer Center West now shows that these women did not participate to a greater degree than the group that was offered the screening for the usual fee.

Contact: Emilia Alfonzo, Researcher at University of Gothenburg
emilia.alfonzo@vgregion.se
University of Gothenburg

Public Release: 21-Mar-2016
Lancet Oncology
High-risk lung cancer patients may not need annual screenings
Most high-risk lung cancer patients might not need annual low-dose computed tomography (LDCT) screenings if they are cleared of disease in their initial test, according to a study led by a Duke Cancer Institute researcher.

Contact: Sarah Avery
sarah.avery@duke.edu
919-660-1306
Duke University Medical Center

Public Release: 21-Mar-2016
Nanomedicine: Nanotechnology, Biology, and Medicine
UGA researchers find potential treatment for prostate cancer
Researchers at the University of Georgia have created a new therapeutic for prostate cancer that has shown great efficacy in mouse models of the disease. They published their findings recently in the journal Nanomedicine: Nanotechnology, Biology and Medicine. The treatment is designed to inhibit the activity of a protein called PAK-1, which contributes to the development of highly invasive prostate cancer cells.
National Institutes of Health, UGA College of Pharmacy, UGA Research Foundation, American Legion, College Scientists Foundation Award

Contact: Stephanie Schupska
schupska@uga.edu
706-542-6927
University of Georgia

Public Release: 21-Mar-2016
Nature Reviews Genetics
Beyond DNA: TGen points the way to enhanced precision medicine with RNA sequencing
Researchers at the Translational Genomics Research Institute (TGen) are showing how genetic analysis using RNA sequencing can vastly enhance that understanding, providing doctors and their patients with more precise tools to target the underlying causes of disease, and help recommend the best course of action. Published today in the journal Nature Reviews Genetics, TGen scientists highlight the many advantages of using RNA-sequencing in the detection and management of everything from cancer to infectious diseases
Ben & Catherine Ivy Foundation of Scottsdale, National Center for Advancing Translational Sciences, Stand Up To Cancer-Melanoma Research Alliance Melanoma Dream Team Translational Cancer Research Grant

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute

Public Release: 21-Mar-2016
EMBO Reports
'Silencer molecules' switch off cancer's ability to spread around body
Scientists have revealed that a key molecule in breast and lung cancer cells can help switch off the cancers' ability to spread around the body. The findings by researchers at Imperial College London, published in the journal EMBO Reports, may help scientists develop treatments that prevent cancer travelling around the body -- or produce some kind of test that allows doctors to gauge how likely a cancer is to spread.
National Institute for Health Research Imperial Biomedical Research Centre, Medical Research Council, Action Against Cancer and the Cancer Treatment and Research Trust

Contact: Kate Wighton
k.wighton@imperial.ac.uk
44-020-759-42410
Imperial College London

Public Release: 21-Mar-2016
Nature Protocols
Individualized cancer treatment targeting the tumor, not the whole body, a step closer
QUT researchers have developed a new 3-D printable hydrogel that opens the way to rapid, personalized cancer treatment by enabling multiple, simultaneous tests to find the correct therapy to target a particular tumor.
Harvard Club of Australia Foundation, National Health and Medical Research Council, Australian Research Council, National Breast Cancer Foundation, Queensland Cancer Council

Contact: Niki Widdowson
n.widdowson@qut.edu.auQUT
61-731-382-999
Queensland University of Technology

Showing releases 1201-1225 out of 1384.

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