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Showing releases 1201-1225 out of 1347.

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Public Release: 15-Dec-2015
Cancer Research
Researchers take first step in precision medicine for penile cancer
Researchers have identified potential genetic alterations in penile cancer that could pave the way for targeted treatments.
A. Alfred Taubman Medical Research Institute

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 15-Dec-2015
Cancer Research
Pitt study: New model of collaborative cancer research may help advance precision medicine
A new system that facilitates data and biospecimen sharing among cancer centers may speed cancer research findings from the laboratory to patient care, according to a new study.
NIH/National Cancer Institute

Contact: Jennifer Yates
YatesJC@upmc.edu
412-647-9966
University of Pittsburgh Schools of the Health Sciences

Public Release: 15-Dec-2015
JAMA
Type of electromagnetic field therapy improves survival for patients with brain tumor
Early research indicates that the use of tumor-treating fields, a type of electromagnetic field therapy, along with chemotherapy in patients with a brain tumor who had completed standard chemoradiation resulted in prolonged progression-free and overall survival, according to a study in the Dec. 15 issue of JAMA.

Contact: Roger Stupp, M.D.
roger.stupp@usz.ch
The JAMA Network Journals

Public Release: 14-Dec-2015
Cancer Epidemiology, Biomarkers & Prevention
Cancer rates decline in many high-income countries, but rise in lower-income countries
Improved screening and detection efforts, combined with decreases in risk factors like smoking, have reduced the incidence and mortality rates from several common types of cancer in many high-income countries. However, many low- and middle-income countries have seen cancer rates rise, partially due to increases in risk factors that are typical of Western countries.
American Cancer Society

Contact: Lauren Riley
lauren.riley@aacr.org
215-446-7155
American Association for Cancer Research

Public Release: 14-Dec-2015
Nature Medicine
Study uncovers hard-to-detect cancer mutations
New research shows that current approaches to genome analysis systematically miss detecting a certain type of complex mutation in cancer patients' tumors. Further, a significant percentage of these complex mutations are found in well-known cancer genes that could be targeted by existing drugs, potentially expanding the number of cancer patients who may benefit.
National Institutes of Health

Contact: Julia Evangelou Strait
straitj@wustl.edu
314-286-0141
Washington University School of Medicine

Public Release: 14-Dec-2015
American Society for Cell Biology 2015
Brain cancer self-organizes into streams, swirls, and spheres
Brain cancer is not anarchy, say researchers but highly organized--self-organized. At ASCB 2015, they report that glioma cells build tumors by self-organizing into streams,10-20 cells wide, that obey a mathematically predicted pattern for autonomous agents flowing together. These streams drag along slower gliomas, may block entry of immune cells, and swirl around a central axis containing glioma stem cells that feed the tumor's growth.

Contact: John Fleischman
jfleischman@ascb.org
513-706-0212
American Society for Cell Biology

Public Release: 14-Dec-2015
Journal of the National Cancer Institute
Continuous joint use of estrogen and progestin lowers risk of EC in postmenopausal women
Adding continuous progestin to estrogen has been shown to lower the risk of endometrial cancer in postmenopausal women according to a study published Dec. 14 in the JNCI: Journal of the National Cancer Institute.

Contact: Zachary Rathner
Zachary.Rathner@oup.com
919-677-2697
Oxford University Press USA

Public Release: 14-Dec-2015
Cancer Cell
Treating colon cancer with vitamin A
Scientists at EPFL have identified the biological pathway behind the growth of colon cancer, and were able block it with vitamin A.
EMBO, Swiss League against Cancer, Swiss National Science Foundation, The National Centre of Competence in Research in Molecular Oncology

Contact: Nik Papageorgiou
n.papageorgiou@epfl.ch
41-216-932-105
Ecole Polytechnique Fédérale de Lausanne

Public Release: 14-Dec-2015
Cancer Cell
Mass. General study identifies potential treatment target for IDH1-mutant cancers
A Massachusetts General Hospital-based research team has identified a potential new treatment target for tumors -- including a significant percentage of malignant brain tumors -- driven by mutations in an important metabolic enzyme.
NIH/National Cancer Institute, Burroughs Wellcome Fund, Society for Nuclear Medicine and Molecular Imaging, Japan Foundation, KANAE Foundation

Contact: Terri Ogan
togan@partners.org
617-726-0954
Massachusetts General Hospital

Public Release: 14-Dec-2015
Cancer Cell
Experimental drugs that change energy supply in cells could slow brain tumor growth
Experimental drugs that alter cell metabolism also halted tumor growth and extended survival in mice with cancers linked to changes in the same gene, according to a new study led by researchers at NYU Langone Medical Center, its Laura and Isaac Perlmutter Cancer Center and Massachusetts General Hospital.

Contact: David March
david.march@nyumc.org
212-404-3528
NYU Langone Medical Center / New York University School of Medicine

Public Release: 14-Dec-2015
Endocrinology Today
Medication protects fertility and defense system during chemotherapy
Researchers found the potent humanin analogue protected male germ cells, which are essential to fertility, and white blood cells, which are the soldiers in the body's defense system, during chemotherapy. They also reported that HNG reduced metastases, or the spread of cancer cells to other organs in the body.
UCLA Clinical and Translational Science Institute, National Institutes of Health

Contact: Laura Mecoy
Lmecoy@labiomed.org
310-546-5860
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed)

Public Release: 14-Dec-2015
PLOS ONE
New method of diagnosing deadly fungal lung infection in leukemia patients discovered
A team of researchers have discovered a new way for early detection of a potentially deadly fungal infection in patients with suppressed immune systems such as those being treated for leukemia or have had an organ transplant.

Contact: Donna Ramirez
donna.ramirez@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston

Public Release: 14-Dec-2015
Journal of Clinical Oncology
Expensive, exploratory research biopsies overused in early studies of new cancer drugs
Early trials of new cancer drugs often require extra biopsies to determine the drugs' biochemical and physiological effects. A new study shows that this costly, risky and often painful process has had no impact on subsequent drug development.

Contact: John Easton
john.easton@uchospitals.edu
773-795-5225
University of Chicago Medical Center

Public Release: 14-Dec-2015
Molecular Cancer Therapeutics
Massey scientists uncover process that could drive the majority of cancers
The gene p53 has been described as the 'guardian of the genome' due to its prominent role in preventing genetic mutations. More than half of all cancers are thought to originate from p53 mutations or loss of function, and now a recent study by VCU Massey Cancer Center scientist Richard Moran, Ph.D., explains why.
NIH/National Cancer Institute

Contact: John Wallace
wallacej@vcu.edu
804-628-1550
Virginia Commonwealth University

Public Release: 14-Dec-2015
Chemistry - A European Journal
Promising cancer therapy advanced by chemical explanation
Radiation therapy: A chilling word that creates images of burn-injuries where the cancer killing ray went through the skin. For decades research hospitals have been investigating the alternative method Hadron therapy, or particle therapy, where runaway cells are bombarded with 'naked' atomic nuclei or protons. When the particles pass through sick cells the collision creates chemical reactions preventing further cell division. Now researchers at the Department of Chemistry, University of Copenhagen, have discovered an unknown reaction caused by the therapy.

Contact: Stephan Sauer
Sauer@chem.ku.dk
45-28-26-22-98
Faculty of Science - University of Copenhagen

Public Release: 14-Dec-2015
Cancer Causes & Control
Colorectal cancer risk varies based on Latino subgroup affiliation
In a first study of its kind, USC researchers have found that colorectal cancer risk in Californian Latinos vary widely depending on their country of origin. 'Nowadays, most of the information we have on the molecular characteristics of colorectal cancer comes from the white population,' said Mariana Stern, lead author and a Latina. 'There is little information specific to Latinos. Plus, they are typically clumped as a group.'
California Department of Public Health, National Cancer Institute's Surveillance, Epidemiology and End Results Program, Cancer Prevention Institute of California, Centers for Disease Control and Prevention's National Program of Cancer Registries

Contact: Zen Vuong
zvuong@usc.edu
213-300-1381
University of Southern California

Public Release: 13-Dec-2015
American Society for Cell Biology 2015
Cancer cell collaborators smooth the way for cancer cells to metastasize
At ASCB 2015, Vanderbilt researchers show how metastasizing tumors use non-cancerous fibroblasts to make a migration highway through surrounding extracellular matrix.

Contact: John Fleischman
jfleischman@ascb.org
513-706-0212
American Society for Cell Biology

Public Release: 12-Dec-2015
Journal of Radiation Oncology
Suicide gene therapy kills prostate tumor cells
Results from a long-term clinical trial conducted by cancer researchers at Houston Methodist Hospital show that combining radiation treatment with 'suicide gene therapy' provides a safe and effective one-two punch against the disease.
NIH/National Cancer Institute, General Clinical Research Center

Contact: Gale Smith
gsmith@houstonmethodist.org
281-627-0439
Houston Methodist

Public Release: 11-Dec-2015
Gastroenterology
Scientists in Barcelona discover a potential treatment for cirrhosis
Cirrhosis is the main risk factor for liver cancer. The same target may be the key to preventing and treating this condition. Cirrhosis figures among the top 20 causes of death from disease worldwide.

Contact: Sònia Armengou
armengou@irbbarcelona.org
34-934-037-255
Institute for Research in Biomedicine (IRB Barcelona)

Public Release: 11-Dec-2015
CA: A Cancer Journal for Clinicians
Review explores cancer screening, prevention, and treatment in people with mental illness
A new report suggests that healthcare system and societal factors are just as critical as individual lifestyle factors in creating health disparities among people with metal illness.

Contact: David Sampson
david.sampson@cancer.org
American Cancer Society

Public Release: 11-Dec-2015
Nature Communications
Fallopian tube organoids promise better understanding of ovarian cancer and infertility
A new way of growing Fallopian tube cells in culture is expected to give a boost to our understanding and prevention of female genital diseases, such as infertility, inflammatory disease, and ovarian cancer.

Contact: Thomas F. Meyer
meyer@mpiib-berlin.mpg.de
49-302-846-0400
Max-Planck-Gesellschaft

Public Release: 11-Dec-2015
American Society for Cell Biology
Non-small cell lung cancers can be sorted in clusters by endocytic changes
Endocytosis is not normal in cancer cells but how dysregulated the process is in cancer cells has just been revealed by Sarah Elkin and colleagues in the University of Texas (UT) Southwestern Medical Center lab of Sandra Schmid. The researchers used three endocytic pathways as markers to sort out 29 non-small cell lung cancer (NSCLC) lines into two distinct clusters characterized by their endocytic dysfunction.

Contact: John Fleischman
jfleischman@ascb.org
513-706-0212
American Society for Cell Biology

Public Release: 11-Dec-2015
Current Biology
Healthy or sick? Tiny cell bubbles may hold the answer
Rutgers scientists have uncovered biological pathways in the roundworm that provide insight into how tiny bubbles released by cells can have beneficial health effects, like promoting tissue repair, or may play a diabolical role and carry disease signals for cancer or neurodegenerative diseases like Alzheimer's.

Contact: Robin Lally
rlally@ucm.rutgers.edu
848-932-0557
Rutgers University

Public Release: 11-Dec-2015
San Antonio Breast Cancer Symposium
MSK studies highlight potential of liquid biopsy at San Antonio Breast Cancer Meeting
Information gleaned from a liquid biopsy may help predict how individual women with advanced breast cancer will respond to certain therapies as well as reveal genetic mutations that can impact prognosis, according to two new studies led by Memorial Sloan Kettering Cancer Center Physician-in-Chief José Baselga and physician-scientist Sarat Chandarlapaty. The studies were presented this week at the San Antonio Breast Cancer Symposium.

Contact: Caitlin Hool
hoolc@mskcc.org
212-639-3573
Memorial Sloan Kettering Cancer Center

Public Release: 11-Dec-2015
Thyroid
Thyroid cancer patients report poor quality of life despite 'good' diagnosis
Thyroid cancer survivors report poor quality of life after diagnosis and treatment compared with other patients who are diagnosed with more lethal cancers, according to new research from the University of Chicago Medicine. The findings, published in the journal Thyroid, shed light on a rarely studied outcome for a growing group of patients who are expected to soon account for 10 percent of all of American cancer survivors.

Contact: Ashley Heher
ashley.heher@uchospitals.edu
773-702-0025
University of Chicago Medical Center

Showing releases 1201-1225 out of 1347.

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