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Showing releases 1201-1216 out of 1216. << < 44 | 45 | 46 | 47 | 48 | 49
Public Release: 5-Feb-2013
 Cancer ResearchMicroRNA molecule may serve as biomarker, target for brain metastases in breast cancer patients MicroRNA molecule called miR-7 decreased in highly metastatic cancer stem-like cells. miR-7 attenuated cancer stem-like cells' capacity for brain metastasis in mice. MicroRNA molecule suppressed KLF4 expression. Contact: Jeremy Moore
Public Release: 5-Feb-2013
RadiologyBenefits of CT outweigh cancer risks in young adults The underlying medical conditions facing young adults who undergo computed tomography (CT) exams represent a significantly greater health risk than that of radiation-induced cancer from CT, according to a new study. Contact: Linda Brooks
Public Release: 4-Feb-2013
Journal of General Internal MedicineYour history may define your future: Tell your doctor In a study published this week in the online version of the Journal of General Internal Medicine, researchers at Brigham and Women's Hospital found that patients who use a web-based risk appraisal tool are more likely to have important family history documented. Contact: Jessica Maki
Public Release: 4-Feb-2013
Journal of Cell SciencePitt researchers reveal mechanism to halt cancer cell growth, discover potential therapy University of Pittsburgh Cancer Institute researchers have uncovered a technique to halt the growth of cancer cells, a discovery that led them to a potential new anti-cancer therapy. When deprived of a key protein, some cancer cells are unable to properly divide, a finding described in the cover story of the February issue of the Journal of Cell Science. This research is supported in part by a grant from the National Institutes of Health. 
National Institutes of Health, PA Department of Health
Contact: Jennifer Yates
Public Release: 4-Feb-2013
Annals of Internal MedicineAnnals of Internal Medicine tip sheet for Feb. 5, 2013 Below is information about articles being published in the February 5 issue of Annals of Internal Medicine. The information is not intended to substitute for the full articles as a source of information. Annals of Internal Medicine attribution is required for all coverage. Contact: Megan Hanks
Public Release: 4-Feb-2013
Proceedings of the National Academy of SciencesUSC scientists design mouse with more human-like immune response Scientists from the University of Southern California have genetically engineered a mouse to more closely mimic a human immune response. The transgenic mouse exhibits humanized CD1d molecules, naturally occurring molecules that activate an especially potent white blood cell called the natural killer T cell. The mouse model has the potential to accelerate development of human immunotherapies for diseases like cancer, diabetes and tuberculosis.
National Institutes of Health
Contact: Alison Trinidad
Public Release: 4-Feb-2013
British Journal of HematologyHigh-dose Vorinostat effective at treating relapsed lymphomas Patients whose aggressive lymphomas have relapsed or failed to respond to the current front-line chemotherapy regimen now have an effective second line of attack against their disease.
National Institutes of Health, Lymphoma Research Foundation, Leukemia and Lymphoma Society, Mary A. Wright Memorial Research Fund, Washington Life Sciences Discovery Fund, Merck Sharp & Dohme Corp
Contact: Dean Forbes
Public Release: 4-Feb-2013
Journal of ImmunologyCan cancer be turned against itself? Prof. Yoel Kloog of Tel Aviv University has found that a family of proteins associated with melanoma can alert the human immune system to the presence of cancer cells. This may lead to a new therapy to augment the anti-cancer immune response, he says, essentially turning cancer against itself. Contact: George Hunka
Public Release: 4-Feb-2013
PLOS ONEMU scientists build harness for powerful radiation cancer therapy In a new study, University of Missouri researchers have demonstrated the ability to harness powerful radioactive particles and direct them toward small cancer tumors while doing negligible damage to healthy organs and tissues. Contact: Christian Basi
Public Release: 4-Feb-2013
Proceedings of the National Academy of SciencesSome cancer mutations slow tumor growth A surprising result suggests that enhancing these mutations' impact could offer a new way to treat cancer.
NIH/National Cancer Institute Physical Sciences Oncology Center
Contact: Sarah McDonnell
Public Release: 4-Feb-2013
February 2013 story tips from Oak Ridge National Laboratory Precise optical imaging is vital for better diagnosis of breast cancer. Researchers at Oak Ridge National Laboratory and New Mexico State University have produced a graphene sheet 40 inches in diagonal. By studying the effects of climate change on the Gulf Coastal region's economy, agriculture and energy production, ORNL researchers are addressing key questions posed by the Department of Energy while designing a tool that the scientific community can use to predict how climate change will impact small localized areas elsewhere. Contact: Ron Walli
Public Release: 4-Feb-2013
CellA little tag with a large effect Ludwig's Oxford researcher Skirmantas Kriaucionis and colleagues at the Rockefeller University in New York published a study on the epigenetic marker known as 5-methylcytosine (5mC). The scientists report that the epigenetic marker 5hmC has an effect on gene expression opposite to that of 5mC. Since changes in the distribution of 5hmC are known to take place in a broad range of tumor cells, these findings could prove to be of great value to cancer research.
Howard Hughes Medical Institute, Spanish MECD, and others
Contact: Rachel Steinhardt
Public Release: 3-Feb-2013
Nature Structural & Molecular BiologyChanges to DNA on-off switches affect cells' ability to repair breaks, respond to chemotherapy Penn cancer biologists have found a key determinant in the balance between two proteins, BRCA1 and 53BP1, in the DNA repair machinery. Breast and ovarian cancer are associated with a breakdown in the repair systems involving these proteins. Their findings appear in the latest online issue of Nature Structural & Molecular Biology.
NIH/National Cancer Institute, American Cancer Society, US Department of Defense
Contact: Karen Kreeger
Public Release: 3-Feb-2013
Nature GeneticsResearchers discover mutations linked to relapse of childhood leukemia After an intensive three-year hunt through the genome, medical researchers have pinpointed mutations that leads to drug resistance and relapse in the most common type of childhood cancer -- the first time anyone has linked the disease's reemergence to specific genetic anomalies. Contact: Christopher Rucas
Public Release: 3-Feb-2013
Nature MedicineGrowth factor aids stem cell regeneration after radiation damage Epidermal growth factor has been found to speed the recovery of blood-making stem cells after exposure to radiation, according to Duke Medicine researchers. The finding could open new options for treating cancer patients and victims of dirty bombs or nuclear disasters.
National Institutes of Health, NIH/National Heart, Lung and Blood Institute, NIH/National Institute of Allergy and Infectious Diseases
Contact: Sarah Avery
Public Release: 3-Feb-2013
Nature ImmunologyImmune cell 'survival' gene key to better myeloma treatments Scientists have identified the gene essential for survival of antibody-producing cells, a finding that could lead to better treatments for diseases where these cells are out of control, such as myeloma and chronic immune disorders. The discovery that a gene called Mcl-1 is critical for keeping this vital immune cell population alive was made by researchers at Melbourne's Walter and Eliza Hall Institute.
National Health and Medical Research Council of Australia, Multiple Myeloma Research Foundation, European Molecular Biology Organization, Victorian Government
Contact: Liz Williams
Showing releases 1201-1216 out of 1216. << < 44 | 45 | 46 | 47 | 48 | 49
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