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Public Release: 12-Feb-2014
Nature
Cancer researchers discover pre-leukemic stem cell at root of AML, relapse
Cancer researchers led by stem cell scientist Dr. John Dick have discovered a pre-leukemic stem cell that may be the first step in initiating disease and also the culprit that evades therapy and triggers relapse in patients with acute myeloid leukemia.

Contact: Jane Finlayson
jane.finlayson@uhn.ca
416-946-2846
University Health Network

Public Release: 12-Feb-2014
JAMA
'Viewpoint' addresses IOM report on genome-based therapeutics and companion diagnostics
The promise of personalized medicine is the ability to tailor therapy to the patient's genome and their cancer's genome using a series of tests, but the system guiding the development of those tests is complex, and plagued with challenges.

Contact: Jennifer Nachbur
jennifer.nachbur@med.uvm.edu
802-656-7875
University of Vermont

Public Release: 12-Feb-2014
British Journal of Cancer
Prostate cancer advance could improve treatment options
Researchers at the University of East Anglia have made an important advance in understanding genetic changes associated with terminal prostate cancer. The research highlights why relapses could happen in some men following hormone therapy. And it could help identify those patients that will develop fatal prostate cancer much earlier for life-extending therapy.
Association for International Cancer Research

Contact: Lisa Horton
press@uea.ac.uk
01-603-593-496
University of East Anglia

Public Release: 12-Feb-2014
Royal Society B
Bees fight to a stalemate in the battle of the sexes according to new research
A new study sheds light on genomic conflict in bumblebees.

Contact: Dr. Eamonn Mallon
ebm3@le.ac.uk
01-162-523-488
University of Leicester

Public Release: 12-Feb-2014
Cell Cycle
New study explains how dense breast tissue drives the early stages of cancer
Scientists from The University of Manchester working with IBM Research have identified a key biological mechanism that for the first time explains why women with dense breast tissue are at greater risk of developing breast cancer.

Contact: Andrew Thompson
andrew@landesbioscience.com
Landes Bioscience

Public Release: 12-Feb-2014
Gerontology
Study highlights long-term effects of childhood obesity on late-life health
"It may be that childhood obesity changes the way the whole metabolism is working -- and changes it during a critical developmental time frame," says Kristen Nadeau, M.D., investigator at the CU Cancer Center.

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 12-Feb-2014
Journal of Antimicrobial Chemotherapy
Popular disinfectants do not kill HPV
Commonly used disinfectants do not kill human papillomavirus (HPV) that makes possible non-sexual transmission of the virus, thus creating a need for hospital policy changes, according to researchers from Penn State College of Medicine and Brigham Young University.
NIH/National Institute of Allergy and Infectious Diseases, Brigham Young University

Contact: Matthew Solovey
msolovey@hmc.psu.edu
717-531-8606
Penn State

Public Release: 11-Feb-2014
Rare cancers: the challenge of accurate diagnosis -- press release
Inaccurate diagnosis is a major obstacle for the proper treatment of patients with rare cancers. A Consensus on Improving the Pathologic Diagnosis of Rare Cancers was presented today by RARE CANCERS EUROPE, together with the European Society for Medical Oncology and the European Society of Pathology in Brussels.

Contact: Rare Cancers Europe Press Office
rarecancereuropenews@esmo.org
33-062-314-5784
European Society for Medical Oncology

Public Release: 11-Feb-2014
Proceedings of the National Academy of Sciences
First observation of a human HAT, key proteins in numerous pathologies
A study published this week in PNAS has revealed the first structure of one of the eight human HATs. This breakthrough paves the way for further research into the functions of the other seven HATs and the resolution of their structures. Moreover, it provides the first sufficiently detailed structural data to tackle their inhibition through drugs.

Contact: Sònia Armengou
armengou@irbbarcelona.org
34-934-037-255
Institute for Research in Biomedicine (IRB Barcelona)

Public Release: 11-Feb-2014
Breast Cancer Research
Alcohol-breakdown molecule may play a role in breast cancer development
Scientists from The University of Manchester -- part of the Manchester Cancer Research Centre -- and the University of Salford looked at a particular enzyme, a biological molecule that accelerates chemical reactions -- known as CYP2E1. Their findings offer a possible target to improve outcomes for patients in the later stages of the disease.
University of Manchester, Ministry of Social Justice and Empowerment, Government of India

Contact: Alison Barbuti
alison.barbuti@manchester.ac.uk
44-016-127-58383
University of Manchester

Public Release: 11-Feb-2014
mBio
A breast cancer drug to fight fungal disease?
The drug tamoxifen appears to kill a fungus associated with a deadly brain infection that afflicts HIV/AIDS patients, according to a University of Rochester study published online today by mBio, the journal of the American Society for Microbiology.
NIH/National Institute of Allergy and Infectious Disease

Contact: Leslie Orr
Leslie_Orr@urmc.rochester.edu
University of Rochester Medical Center

Public Release: 11-Feb-2014
JAMA
Three doses of HPV vaccine recommended against genital warts
Two doses of vaccine against human papillomavirus provide good protection against genital warts, but three doses is better according to an extensive register study by researchers at Karolinska Institutet in Sweden.
Swedish Foundation for Strategic Research

Contact: Press Office
pressinfo@ki.se
46-852-486-077
Karolinska Institutet

Public Release: 11-Feb-2014
Biology of Blood and Marrow Transplantation
Study: Resilience in parents of children undergoing stem cell transplant
After a child's stem cell transplant, parents feel increased distress at the time of the procedure, but eventually recover to normal levels of adjustment.
National Institutes of Health

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 11-Feb-2014
Psychological Medicine
Smoking cessation may improve mental health
Although many health professionals who treat people with psychiatric problems overlook their patients' smoking habits, new research at Washington University School of Medicine in St. Louis shows that people who struggle with mood problems or addiction can safely quit smoking and that kicking the habit is associated with improved mental health.
NIH/National Center for Research Resources, NIH/National Institute on Drug Abuse, American Cancer Society

Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine

Public Release: 11-Feb-2014
Autophagy
Acidic tumor pH inhibits drug effect
Low pH in tumors counteracts the desired effect of the drug chloroquine, according to a new study from Karolinska Institutet in Sweden. The results, which are published in the journal Autophagy, might explain possible lack of efficacy of chloroquine in clinical studies.
Association for International Cancer Research, Swedish Cancer Society, and others

Contact: Press Office
pressinfo@ki.se
46-852-486-077
Karolinska Institutet

Public Release: 11-Feb-2014
Proceedings of the National Academy of Sciences
A new postal code for cancer
Prof. Prasad Shastri and his Team from the University of Freiburg/Germany have discovered that a polymer can provide a key to get into tumors.

Contact: Dr. V. Prasad Shastri
prasad.shastri@makro.uni-freiburg.de
49-761-203-6268
University of Freiburg

Public Release: 11-Feb-2014
Leukemia
New target isolated for leukemia drug development
The protein WTAP and its relationship to Heat shock protein 90 are two discoveries at The University of Texas Health Science Center at San Antonio that open the door to developing more effective therapies in Acute Myeloid Leukemia.
Castella Endowment for Aging Research; NIH/National Cancer Institute, National Institutes of Health, Hyundai Hope on Wheels

Contact: Elizabeth Allen
allenea@uthscsa.edu
210-450-2020
University of Texas Health Science Center at San Antonio

Public Release: 11-Feb-2014
Nature
Researchers find source of new lineage of immune cells
The elusive progenitor cells that give rise to innate lymphoid cells -- a recently discovered group of infection-fighting white blood cells -- have been identified in fetal liver and adult bone marrow of mice.
National Institutes of Health, Howard Hughes Medical Institute

Contact: John Easton
john.easton@uchospitals.edu
773-795-5225
University of Chicago Medical Center

Public Release: 11-Feb-2014
British Medical Journal
Double mastectomy halves death risk for women with BRCA-related breast cancer
Women with BRCA-related breast cancer who have a double mastectomy are nearly 50 percent less likely to die of breast cancer within 20 years of diagnosis compared to women who have a single mastectomy, according to a new study led by Women's College Hospital's Kelly Metcalfe.

Contact: Julie Saccone
julie.saccone@wchospital.ca
416-323-6400 x4054
Women's College Hospital

Public Release: 11-Feb-2014
Radiotherapy & Oncology
Skin reactions during radiation therapy preventable
Severe skin reactions during radiation therapy could be prevented by applying a thin transparent silicone dressing to the skin from the first day of treatment, a clinical trial shows.

Contact: Patries Herst
patries.herst@otago.ac.nz
University of Otago

Public Release: 11-Feb-2014
Proceedings of the National Academy of Sciences
UNC study reveals potential route to bladder cancer diagnostics, treatments
UNC School of Medicine researchers conducted a genetic analysis of invasive bladder cancer tumors to discover that the disease shares genetic similarities with two forms of breast cancer.
National Institutes of Health

Contact: William Davis
william_davis@med.unc.edu
919-966-5906
University of North Carolina Health Care

Public Release: 11-Feb-2014
Cancer Cell
New UK study shows potential for targeting aggressive breast cancers
A new study led by University of Kentucky Markey Cancer Center researcher Peter Zhou shows that targeting Twist, a nuclear protein that is an accelerant of the epithelial-mesenchymal transition program in human cells, may provide an effective approach for treating triple-negative breast cancer.

Contact: Allison Perry
allison.perry@uky.edu
859-323-2399
University of Kentucky

Public Release: 11-Feb-2014
Tobacco Control
I smoke, but I'm not a smoker
While smoking among California adults has dramatically declined in recent decades, researchers at the University of California, San Diego School of Medicine report there is a surprisingly large number of people who say they use cigarettes, but don't consider themselves to be "smokers."
State of California Department of Health Services, University of California, San Diego

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 11-Feb-2014
Journal of American College of Surgeons
Game changer: Biomarker identified for noncancerous pancreatic cysts
Researchers at the Indiana University School of Medicine have discovered a highly accurate, noninvasive test to identify benign pancreatic cysts.

Contact: Mary Hardin
mhardin@iu.edu
317-274-5456
Indiana University

Public Release: 11-Feb-2014
2014 AAAS Annual Meeting
Targeting tumors: Ion beam accelerators take aim at cancer
Hear the latest in the development of particle accelerators for delivering cancer-killing beams from a physicist, a radiobiologist, and a clinical oncologist, and participate in a discussion about cost, access, and ethics.

Contact: Karen McNulty Walsh
kmcnulty@bnl.gov
631-344-8350
DOE/Brookhaven National Laboratory

Showing releases 1201-1225 out of 1281.

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