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Showing releases 1201-1225 out of 1235.

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Public Release: 28-Apr-2014
Nature Genetics
Loss of Y chromosome can explain shorter life expectancy and higher cancer risk for men
It is generally well known that men have an overall shorter life expectancy compared to women. A recent study, led by Uppsala University researchers, shows a correlation between a loss of the Y chromosome in blood cells and both a shorter life span and higher mortality from cancer in other organs.

Contact: Jan Dumanski
jan.dumanski@igp.uu.se
46-018-471-5035
Uppsala University

Public Release: 28-Apr-2014
Cancer
Receiving chemotherapy after a breast cancer diagnosis may affect a patient's employment
A new study has found that loss of paid employment after a diagnosis of early-stage breast cancer may be common and potentially related to the type of treatment patients received.

Contact: Evelyn Martinez
sciencenewsroom@wiley.com
Wiley

Public Release: 28-Apr-2014
Current Oncology
Breast cancer patients place huge emphasis on gene expression profiling test
Gene expression profiling tests play a critical role when women with early-stage breast cancer decide whether to have chemotherapy, but many of them do not fully understand what some of the test results mean, new research suggests.
Cancer Care Ontario, Ontario Institute for Cancer Research

Contact: Leslie Shepherd
shepherdl@smh.ca
416-864-6094
St. Michael's Hospital

Public Release: 28-Apr-2014
Chromatographia
Two breath compounds could be associated with larynx cancer
Researchers at the Rey Juan Carlos University and the Alcorcon Hospital (Madrid) have compared the volatile substances exhaled by eleven people with cancer of larynx, with those of another twenty healthy people. The results show that the concentrations of certain molecules, mainly ethanol and 2-butanone, are higher in individuals with carcinoma, therefore they act as potential markers of the disease.

Contact: SINC
info@agenciasinc.es
34-914-251-820
FECYT - Spanish Foundation for Science and Technology

Public Release: 28-Apr-2014
Cancer
Unemployment common after breast cancer treatment
Nearly one-third of breast cancer survivors who were working when they began treatment were unemployed four years later. Women who received chemotherapy were most affected, according to a new study from the University of Michigan Comprehensive Cancer Center.
NIH/National Cancer Institute, American Cancer Society

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 28-Apr-2014
Journal of Biological Chemistry
Researchers identify potential new strategy to treat ovarian cancer
Scientists studying cancerous tumor tissues in a laboratory believe they have identified a potential new strategy to treat ovarian cancer -- which affects around 7,000 women in the UK each year.

Contact: Alison Barbuti
alison.barbuti@manchester.ac.uk
44-016-127-58383
University of Manchester

Public Release: 28-Apr-2014
Nature
Researchers identify mechanism of cancer caused by loss of BRCA1 and BRCA2 gene function
Inherited mutations in the BRCA1 or BRCA2 tumor suppressor genes are by far the most frequent contributors of hereditary cancer risk in the human population, often causing breast or ovarian cancer in young women of child-bearing age. Now investigators at Beth Israel Deaconess Medical Center report a new mechanism by which BRCA gene loss may accelerate cancer-promoting chromosome rearrangements.
National Institutes of Health, American Cancer Society

Contact: Bonnie Prescott
bprescot@bidcm.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center

Public Release: 28-Apr-2014
Nature Reviews Cancer
Imaging gives clearer picture of cancer drugs' chances of success
The quest for new cancer treatments could be revolutionized by advances in technology that can visualize living cells and tissues, scientists claim.

Contact: Jen Middleton
jen.middleton@ed.ac.uk
44-131-650-6514
University of Edinburgh

Public Release: 25-Apr-2014
eLife
A civil war inside our cells: Scientists show how our bodies fight off 'jumping genes'
There's a civil war going on inside every one of the 37 trillion cells in your body. Now, University of Michigan scientists have uncovered how your cells keep this war from causing too much collateral damage.
Howard Hughes Medical Institute

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 25-Apr-2014
Biofabrication
3-D printing cancer tumors
Wei Sun, Ph.D., a mechanical engineering researcher at Drexel University, has devised a method for 3-D printing tumors that could soon be taking cancer research out of the petri dish.
National Science Foundation

Contact: Britt Faulstick
bef29@drexel.edu
215-895-2617
Drexel University

Public Release: 25-Apr-2014
Journal of Clinical Investigation
Researchers generate immunity against tumor vessel protein
A group of researchers from the Abramson Cancer Center and the Perelman School of Medicine at the University of Pennsylvania is employing a novel DNA vaccine to kill cancer, not by attacking tumor cells, but targeting the blood vessels that keep them alive. The vaccine also indirectly creates an immune response to the tumor itself, amplifying the attack by a phenomenon called epitope spreading. The results of the study were published this month in the Journal of Clinical Investigation.
Pennsylvania Department of Health

Contact: Katie Delach
katie.delach@uphs.upenn.edu
215-776-6063
University of Pennsylvania School of Medicine

Public Release: 24-Apr-2014
Blood
Moffitt Cancer Center's phase 3 study may be game-changer for acute myeloid leukemia
Moffitt Cancer Center researchers say clinical trials for a new experimental drug to treat acute myeloid leukemia are very promising. Patients treated with CPX-351, a combination of the chemotherapeutic drugs cytarabine and daunorubicin, are showing better responses than patients treated with the standard drug formulation.
Celator Pharmaceuticals

Contact: Kim Polacek
kim.polacek@moffitt.org
813-745-7408
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 24-Apr-2014
Cell Reports
Scientists find way to target cells resistant to chemo
Scientists from The University of Manchester have identified a way to sensitize cancer cells to chemotherapy -- making them more open to treatment.

Contact: Kath Paddison
kath.paddison@manchester.ac.uk
01-612-755-2111
University of Manchester

Public Release: 24-Apr-2014
Chemistry & Biology
Large-scale identification and analysis of suppressive drug interactions
Cell analysis finds drug interactions to be startlingly common: baker's yeast is giving scientists a better understanding of drug interactions, which are a major cause of illness and hospitalization worldwide.

Contact: Polly Thompson
pthompson@lunenfeld.ca
416-586-4800 x2046
Lunenfeld-Tanenbaum Research Institute

Public Release: 24-Apr-2014
Cell
Surprising new insights into the PTEN tumor suppressor gene
Ever since it was first identified more than 15 years ago, the PTEN gene has been known to play an integral role in preventing the onset and progression of numerous cancers. Now investigators at Beth Israel Deaconess Medical Center explain more precisely how PTEN exerts its anti-cancer effects and how its loss or alteration can set cells on a cancerous course.
National Inistitutes of Health, American-Italian Cancer Foundation

Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center

Public Release: 24-Apr-2014
Neoplasia
New study helps to explain why breast cancer often spreads to the lung
New research led by Alison Allan, Ph.D., a scientist at Western University and the Lawson Health Research Institute, shows why breast cancer often spreads or metastasizes to the lung. The breast cancer stem cell (CSC) has been shown to be responsible for metastasis in animal models, particularly to the lung. And this new research found CSCs have a particular propensity for migrating towards and growing in the lung because of certain proteins found there.
Canadian Breast Cancer Foundation-Ontario Region

Contact: Kathy Wallis
kwallis3@uwo.ca
519-661-2111 x81136
University of Western Ontario

Public Release: 24-Apr-2014
Journal of Pathology
Finnish team of researchers finds a mutation in a tumor of the jaw
A Finnish team of researchers was the first in the world to discover a gene mutation in ameloblastoma, which is a tumor of the jaw. Researchers have been searching for the mutation that causes ameloblastoma for decades, and this mutation has now been found in a patient living in the eastern part of Finland.

Contact: Kristiina Heikinheimo
krihei@uef.fi
358-505-642-669
University of Eastern Finland

Public Release: 24-Apr-2014
Journal of Clinical Investigation
JCI online ahead of print table of contents for April 24, 2014
This release contains summaries, links to PDFs, and contact information for the following newsworthy papers published online, April 24, 2014, in the JCI: 'Ex vivo expansion of hematopoietic stem cells from cord blood,' 'Receptors in the brain mediate the weight loss effects of GLP1 agonists,' 'Peripheral nervous system plasmalogens regulate Schwann cell differentiation and myelination,' 'Estrogen promotes Leydig cell engulfment by macrophages in male infertility,' and more.

Contact: Corinne Williams
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 24-Apr-2014
International Journal of Cancer
Breast cancer replicates brain development process
New research led by a scientist at the University of York reveals that a process that forms a key element in the development of the nervous system may also play a pivotal role in the spread of breast cancer.
United Kingdom Medical Research Council

Contact: David Garner
david.garner@york.ac.uk
44-019-043-22153
University of York

Public Release: 23-Apr-2014
Journal of Adolescent Health
RI Hospital physician: Legalizing medical marijuana doesn't increase use among adolescents
Parents and physicians concerned about an increase in adolescents' marijuana use following the legalization of medical marijuana can breathe a sigh of relief. According to a new study at Rhode Island Hospital, which compared 20 years worth of data from states with and without medical marijuana laws, legalizing the drug did not lead to increased use among adolescents. The study is published online in advance of print in the Journal of Adolescent Health.

Contact: Ellen Slingsby
eslingsby@lifespan.org
401-444-6421
Lifespan

Public Release: 23-Apr-2014
Cancer Research
Scientists identify cancer specific cell for potential treatment of gastric cancer
A team of scientists led by a researcher from the Cancer Science Institute of Singapore at the National University of Singapore has identified the cancer specific stem cell which causes gastric cancer. This discovery opens up the possibility of developing new drugs for the treatment of this disease and other types of cancers.

Contact: Kimberley Wang
kimberley.wang@nus.edu.sg
National University of Singapore

Public Release: 23-Apr-2014
Chemical Science
Following a protein's travel inside cells is key to improving patient monitoring, drug development
Virginia Tech chemical engineer Chang Lu and his colleagues have used a National Science Foundation grant to develop a technique to detect subcellular location of a protein.
National Science Foundation

Contact: Lynn Nystrom
tansy@vt.edu
540-231-4371
Virginia Tech

Public Release: 23-Apr-2014
Molecular Cell
Study identifies enzymes that help fix cancer-causing DNA defects
Purdue University researchers have identified an important enzyme pathway that helps prevent new cells from receiving too many or too few chromosomes, a condition that has been directly linked to cancer and other diseases.
National Institutes of Health, Purdue University Center for Cancer Research

Contact: Natalie van Hoose
nvanhoos@purdue.edu
765-496-2050
Purdue University

Public Release: 23-Apr-2014
Practical Radiation Oncology
ASTRO issues guideline on the role of postoperative radiation therapy for endometrial cancer
The American Society for Radiation Oncology (ASTRO) has issued a new guideline, 'The Role of Postoperative Radiation Therapy for Endometrial Cancer: An ASTRO Evidence-Based Guideline,' that details the use of adjuvant radiation therapy in the treatment of endometrial cancer.

Contact: Michelle Kirkwood
michellek@astro.org
703-286-1600
American Society for Radiation Oncology

Public Release: 23-Apr-2014
Nature Nanotechnology
Gold nanoparticles help target, quantify breast cancer segments in a living cell
Purdue University researchers have developed a way to detect and measure cancer levels in a living cell by using tiny gold particles with tails of synthetic DNA.
National Science Foundation, Indiana Clinical Transitional Sciences Institute, Purdue Center for Cancer Research, Samsung

Contact: Natalie van Hoose
nvanhoos@purdue.edu
765-496-2050
Purdue University

Showing releases 1201-1225 out of 1235.

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