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Showing releases 1226-1250 out of 1265.

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Public Release: 23-Jun-2014
Study sheds light on racial disparity in colon cancer
African-Americans with colon cancer are half as likely as Caucasian patients to have a type of colon cancer that is linked to better outcomes. The finding may provide insight into why African-Americans are more likely to die of colon cancer than Caucasians with the same stage of disease.
National Institutes of Health

Contact: Nicole Fawcett
University of Michigan Health System

Public Release: 23-Jun-2014
Annals of Internal Medicine
Annals of Internal Medicine tip sheet for June 24, 2014
The June 24, 2014, Annals of Internal Medicine contains papers titled: 'Task Force recommends one-time screening for abdominal aortic aneurysms in older male smokers' and 'Caution advised before implementing widespread lung cancer screening among Medicare beneficiaries.'

Contact: Megan Hanks
American College of Physicians

Public Release: 22-Jun-2014
Microenvironment of hematopoietic stem cells can be a target for myeloproliferative disorders
The protective microenvironment of the hematopoietic stem cell niche, which produces cells of the blood and the immune system, also protects against myeloproliferative neoplasia.

Contact: AInhoa Iriberri
Centro Nacional de Investigaciones Cardiovasculares

Public Release: 22-Jun-2014
Cancer by remote-control
One of the deadliest forms of paediatric brain tumour, Group 3 medulloblastoma, is linked to a variety of large-scale DNA rearrangements which all have the same overall effect on specific genes located on different chromosomes. The finding, by scientists at EMBL Heidelberg and collaborators, is published online today in Nature.
German Cancer Aid, German Federal Ministry of Education and Research

Contact: Sonia Furtado Neves
European Molecular Biology Laboratory

Public Release: 22-Jun-2014
Researchers discover new genes that promote brain cancer
Study identifies two novel oncogenes that cause childhood brain cancer when activated.

Contact: Susan Gammon, Ph.D.
Sanford-Burnham Medical Research Institute

Public Release: 22-Jun-2014
BPA exposure during fetal development raises risk of precancerous prostate lesions
A new study has found for the first time that the endocrine-disrupting chemical bisphenol A, BPA, reprograms the developing prostate, making the gland more susceptible to precancerous lesions and other diseases later in a man's life. The results will be reported Sunday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.

Contact: Aaron Lohr
The Endocrine Society

Public Release: 22-Jun-2014
Growth hormone defect may protect against diabetes, cancer in unique ecuador population
People who lack growth hormone receptors also appear to have marked insulin sensitivity that prevents them from developing diabetes and lowers their risk for cancer, despite their increased percentage of body fat, new research finds. The results were presented Sunday, June 22, at ICE/ENDO 2014, the joint meeting of the International Society of Endocrinology and the Endocrine Society in Chicago.
The Instituto de Endocrinologia Metabolismo y Reproducción

Contact: Aaron Lohr
The Endocrine Society

Public Release: 21-Jun-2014
Possible new weapon found for fighting some types of breast cancer
Researchers believe they have discovered one reason why some women with estrogen receptor-positive breast cancer may respond poorly or only temporarily to estrogen-blocking drugs such as tamoxifen. Results of a new study, which was presented Saturday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago, point to a previously unrecognized role of the androgen receptor.

Contact: Aaron Lohr
The Endocrine Society

Public Release: 20-Jun-2014
For cancer patients, new tool predicts financial pain
Cancer care has a new side effect. Patients now have to deal with 'financial toxicity,' the expense, anxiety and loss of confidence confronting those who face large, unpredictable costs, often compounded by decreased ability to work. A team of cancer specialists describe COST, the first tool to measure a patient's risk for, and ability to tolerate, financial stress.
National Institutes of Health

Contact: John Easton
University of Chicago Medical Center

Public Release: 20-Jun-2014
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
Festschrift issue for Hilary Koprowski, MD
The June issue of Monoclonal Antibodies in Immunodiagnosis and Immunotherapy is a special tribute issue for Hilary Koprowski, MD (1916-2013).

Contact: Vicki Cohn
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 20-Jun-2014
Cancer Causes & Control
Menthol cigarettes linked to increased smoking among teens
Teens who use menthol cigarettes smoke more cigarettes per day than their peers who smoke non-menthols, says a new study. The findings from the Propel Centre for Population Health Impact at the University of Waterloo mark the first time that menthol cigarettes have been directly linked to elevated nicotine addiction among youth in Canada.
Canadian Cancer Society

Contact: Pamela Smyth
University of Waterloo

Public Release: 19-Jun-2014
Lancet Oncology
Researcher discovers ovarian cancer treatment
Doctors at the University of Arizona Cancer Center at St. Joseph's Hospital and Medical Center in Phoenix reported today in Lancet Oncology that a new treatment for ovarian cancer can improve response rates (increase the rate of tumor shrinkage) and prolong the time until cancers recur. In addition, this breakthrough showed a trend in improving survival although these data are not yet mature.

Contact: lynne Reaves
St. Joseph's Hospital and Medical Center

Public Release: 19-Jun-2014
Proceedings of the National Academy of Sciences
Possible new combination treatment for cancer
Scientists at the Sahlgrenska Academy have developed a new cancer treatment that has proved to be effective in mice. The treatment, which is presented in the prestigious scientific journal PNAS, is based on newly discovered properties of the so-called BET bromodomain inhibitors.

Contact: Krister Svahn
University of Gothenburg

Public Release: 19-Jun-2014
JAMA Surgery
African American women with breast cancer less likely to have newer, recommended surgical procedure
African American women with early stage, invasive breast cancer were 12 percent less likely than Caucasian women with the same diagnosis to receive a minimally invasive technique, axillary sentinel lymph node biopsy, even as the procedure had become the standard of surgical practice, according to research from The University of Texas MD Anderson Cancer Center.

Contact: Laura Sussman
University of Texas M. D. Anderson Cancer Center

Public Release: 19-Jun-2014
Computer-designed protein triggers self-destruction of Epstein-Barr-infected cancer cells
A protein molecule, BINDI, has been built to trigger self-destruction of cancer cells infected with the Epstein-Barr virus.
National Institutes of Health, Washington Life Sciences Discovery Fund, US Defense Threat Reduction Agency, and others

Contact: Elizabeth Hunter
University of Washington Health Sciences/UW Medicine

Public Release: 19-Jun-2014
Cleveland Clinic researchers discover protein that inhibits tumor growth
A previously unknown variant of an extensively studied protein has been found to inhibit the growth of tumors and slow the development of new blood vessels necessary for cancers to metastasize, according to Cleveland Clinic research published today in Cell.
National Institutes of Health

Contact: Laura Ambro
Cleveland Clinic

Public Release: 19-Jun-2014
Pigment Cell & Melanoma Research
Study offers evidence that sunscreen use in childhood prevents melanoma in adults
Research conducted at the Texas Biomedical Research Institute, published in the latest issue of the scientific journal Pigment Cell and Melanoma, has established unequivocally in a natural animal model that the incidence of malignant melanoma in adulthood can be dramatically reduced by the consistent use of sunscreen in infancy and childhood.
Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation

Contact: Mary Uhlig
210-227-0221 x223
Texas Biomedical Research Institute

Public Release: 19-Jun-2014
Scientists identify additional challenges in KRAS-driven cancers
Scientists have redoubled efforts to disable the mutated cancer gene KRAS, which confers an especially poor prognosis and has proved extraordinarily difficult to target. New research reported in the journal Cell has identified an additional hurdle: inhibiting KRAS can activate a backup pathway in cancer cells that enables them to survive and thrive in the oncogene's absence.
NIH/National Cancer Institute, Koch Institute

Contact: Teresa M Herbert
Dana-Farber Cancer Institute

Public Release: 19-Jun-2014
Cell Reports
A new tool to confront lung cancer
Published online in Cell Reports on June 19, Huntsman Cancer Institute investigators report that misregulation of two genes, sox2 and lkb1, drives squamous cell lung cancer in mice. The discovery uncovers new treatment strategies, and provides a clinically relevant mouse model in which to test them.
US Department of Defense, V Foundation for Cancer Research, Damon Runyon Cancer Research Foundation

Contact: Linda Aagard
University of Utah Health Sciences

Public Release: 19-Jun-2014
Drug shows promise for the first time against metastatic melanoma of the eye
For the first time, a therapy has been found that can delay progression of metastatic uveal melanoma, a rare and deadly form of melanoma of the eye.
NIH/National Cancer Institute

Contact: Karin Eskenazi
Columbia University Medical Center

Public Release: 19-Jun-2014
Optics Letters
A better imager for identifying tumors
Researchers have developed a new technique that could improve surgeons' ability to identify cancerous tumors and remove them in real-time in the operating room. The new imaging system combines two techniques -- near-IR fluorescent imaging and visible light reflectance imaging -- to get a much better picture of the tissue. The work, from the University of Arizona and Washington University in St. Louis, was published in the journal Optics Letters today.

Contact: Lyndsay Meyer
The Optical Society

Public Release: 19-Jun-2014
Mechanism discovered for attaching an 'on' switch that helps cells accessorize proteins
St. Jude Children's Research Hospital scientists have discovered how an important 'on' switch is attached to the machinery that cells rely on to adapt thousands of proteins to meet changing conditions. The research appears in the current issue of the journal Cell.
NIH/National Cancer Institute, NIH/National Institute of General Medical Sciences, Howard Hughes Medical Institute, Damon Runyon Cancer Research Foundation, ALSAC

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Public Release: 19-Jun-2014
Cell Stem Cell
Scientists identify link between stem cell regulation and the development of lung cancer
UCLA researchers led by Dr. Brigitte Gomperts have discovered the inner workings of the process thought to be the first stage in the development of lung cancer. Their study explains how factors that regulate the growth of adult stem cells that repair tissue in the lungs can lead to the formation of precancerous lesions.

Contact: Shaun Mason
University of California - Los Angeles

Public Release: 19-Jun-2014
New target: Researchers identify pancreatic cancer resistance mechanism
Pancreatic cancer tumors addicted to mutant Kras signaling for their growth and progression have a ready-made substitute to tap if they're ever forced to go cold-turkey on the mutant oncogene, scientists at The University of Texas MD Anderson Cancer Center report in the journal Cell.

Contact: Scott Merville
University of Texas M. D. Anderson Cancer Center

Public Release: 19-Jun-2014
Gynecologic Oncology
Finding the Achilles' Heel of ovarian tumor growth
A team of scientists, led by principal investigator David D. Schlaepfer, PhD, professor in the Department of Reproductive Medicine at the University of California, San Diego School of Medicine report that small molecule inhibitors to a protein called focal adhesion kinase selectively prevent the growth of ovarian cancer cells as tumor spheroids.
National Institutes of Health, Nine Girls Ask?

Contact: Scott LaFee
University of California - San Diego

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