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Showing releases 126-150 out of 1357.

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Public Release: 10-Jun-2015
New England Journal of Medicine
Researchers take a major step in reclassifying brain tumors with precision
A Cancer Genome Atlas study on diffuse gliomas finds genomic analysis predicts tumor behavior better than microscope appearance
NIH/National Cancer Institute

Contact: Judy Fortin
judy.fortin@emory.edu
404-778-4580
Emory Health Sciences

Public Release: 10-Jun-2015
New England Journal of Medicine
Genetic markers provide better brain cancer classification
A team of scientists from UC San Francisco and Mayo Clinic has shown that using just three molecular markers will help clinicians classify gliomas -- the most common type of malignant brain tumors -- more accurately than current methods.
National Institutes of Health, Bernie and Edith Waterman Foundation, Ting Tsung and Wei Fong Chao Family Foundation, National Center for Research Resources, National Center for Advancing Translational Sciences, National Brain Tumor Foundation, and others

Contact: Elizabeth Fernandez
elizabeth.fernandez@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 9-Jun-2015
Scientific Reports
MIPT physicists develop ultrasensitive nanomechanical biosensor
Two young researchers working at the MIPT Laboratory of Nanooptics and Plasmonics, Dmitry Fedyanin and Yury Stebunov, have developed an ultracompact highly sensitive nanomechanical sensor for analyzing the chemical composition of substances and detecting biological objects, such as viral disease markers, which appear when the immune system responds to incurable or hard-to-cure diseases, including HIV, hepatitis, herpes, and many others. The sensor will enable doctors to identify tumor markers, whose presence in the body signals the emergence and growth of cancerous tumors.

Contact: Stanislav Goryachev
stas.goryachev@gmail.com
7-964-501-2307
Moscow Institute of Physics and Technology

Public Release: 9-Jun-2015
23rd World Congress of Dermatology
Molescope to be unveiled at World Dermatology Conference in Vancouver
Simon Fraser University Ph.D. graduate Maryam Sadeghi will unveil MoleScope™, an innovative hand-held tool that uses a smartphone to monitor skin for signs of cancer, at the World Congress of Dermatology conference in Vancouver June 9-13. MoleScope™ enables people to monitor their moles and skin health, share images with family and healthcare providers and eventually, connect skin specialists with people online.

Contact: Marianne Meadahl
Marianne_Meadahl@sfu.ca
778-782-3210
Simon Fraser University

Public Release: 9-Jun-2015
JAMA Oncology
Chemo may be preferred option for some with advanced prostate cancer
In a small clinical trial, scientists at Johns Hopkins' Kimmel Cancer Center and James Buchanan Brady Urological Institute found that men with advanced prostate cancer and detection of androgen receptor splice variant-7 respond to chemotherapy just as well as men who lack the variant.
Prostate Cancer Foundation, DOD/Prostate Cancer Research Program Patrick C. Walsh Fund, Johns Hopkins Prostate SPORE, National Institutes of Health

Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medicine

Public Release: 9-Jun-2015
Immunity
How a gut feeling for infection programs our immune response
An unexpected finding by an international team of scientists based at The University of Manchester and National Institutes of Health in America has shed new light on how immune cells are programmed to either repair or protect the body.
Wellcome Trust, The Royal Society, NIH/National Institute of Allergy and Infectious Diseases

Contact: Morwenna Grills
Morwenna.Grills@manchester.ac.uk
44-016-127-52111
University of Manchester

Public Release: 9-Jun-2015
Proceedings of the National Academy of Sciences
Study redefines role of estrogen in cervical cancer
Scientists have prior evidence that the hormone estrogen is a major driver in the growth of cervical cancer, but a new study examining genetic profiles of 128 clinical cases reached a surprising conclusion -- estrogen receptors all but vanish in cervical cancer tumors.
National Institutes of Health, Morgridge Institute for Research

Contact: Johan den Boon
jdenboon@morgridge.org
608-316-4462
University of Wisconsin-Madison

Public Release: 9-Jun-2015
Lancet Oncology
Single dose of HPV vaccine may prevent cervical cancer
A single dose of the human papillomavirus (HPV) vaccine Cervarix appears to be as effective in preventing certain HPV infections as three doses, the currently recommended course of vaccination. That is the conclusion of a study published today in The Lancet Oncology and co-authored by Diane Harper, M.D., Ph.D., the Rowntree Endowed Chair and professor in the Department of Family and Geriatric Medicine at the University of Louisville School of Medicine.

Contact: Betty Coffman
betty.coffman@louisville.edu
502-852-4573
University of Louisville

Public Release: 9-Jun-2015
Molecular Cell
UTSW scientists find cellular mechanism for how the body regulates glucose transport
UT Southwestern Medical Center scientists have gleaned a key cellular mechanism of how the body adjusts glucose levels, an important process that when abnormal can promote diabetes, cancer, and rare genetic diseases.
NIH/National Cancer Institute, Burroughs Wellcome Fund, American Cancer Society, Harold C. Simmons Comprehensive Cancer Center, Disease Oriented Clinical Scholar Awards, Department of Dermatology

Contact: Russell Rian
russell.rian@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center

Public Release: 8-Jun-2015
Proceedings of the National Academy of Sciences
Navigating multiple myeloma with 'Google Maps' for the cancer genome
In a new study published June 8 in the Proceedings of the National Academy of Sciences, David Schwartz and his University of Wisconsin-Madison research team describe a new approach for studying the cancer genome that Schwartz says will let scientists account for both the individual tiles and the whole mosaic. It enables researchers and clinicians to look at the small- and large-scale genetic changes that define individual cancers.

Contact: Dave Schwartz
dcschwartz@wisc.edu
608-358-1283
University of Wisconsin-Madison

Public Release: 8-Jun-2015
Health Affairs
Who your doctor is could dictate how you're cared for at end of life
New research from Brigham and Women's Hospital indicates that the individual physician a patient sees is the strongest known predictor of whether or not he or she will enroll in hospice care, outweighing other known drivers such as geographic location, patient age, race and comorbidities.
National Institutes of Health Common Fund

Contact: Lori J. Schroth
ljschroth@partners.org
617-525-6374
Brigham and Women's Hospital

Public Release: 8-Jun-2015
National Cancer Intelligence Network Cancer Outcomes Conference 2015
Women four times less likely to have surgery if breast cancer diagnosed as an emergency
Breast cancer patients are four times less likely to have potentially lifesaving surgery if diagnosed as an emergency rather than through an urgent GP referral, according to a new data published Monday at the NCIN Cancer Outcomes conference.
Cancer Research UK, Public Health England

Contact: Paul Thorne
paul.thorne@cancer.org.uk
44-203-469-8352
Cancer Research UK

Public Release: 8-Jun-2015
Nature Genetics
Novel mutational process targeting gene regulatory elements discovered
Researchers at University of Helsinki, Finland, and Karolinska Institutet, Sweden, discovered previously uncharacterized mutational patterns in the human regulatory genome, especially in gastrointestinal tract cancers.

Contact: Lauri Aaltonen
lauri.aaltonen@helsinki.fi
358-404-435-041
University of Helsinki

Public Release: 8-Jun-2015
Cancer Cell
Disrupting tumor cell 'microenvironment' suggests a new way to treat a prevalent childhood leukemia
Researchers at NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center are reporting a potentially important discovery in the battle against one of the most devastating forms of leukemia that accounts for as many as one in five children with a particularly aggressive form of the disease relapsing within a decade.

Contact: David March
david.march@nyumc.org
212-404-3528
NYU Langone Medical Center / New York University School of Medicine

Public Release: 8-Jun-2015
Journal of Clinical Oncology
Early attention to quality of life reduces hospital costs for advanced cancer patients
Earlier introduction of palliative care for patients hospitalized with advanced cancer is associated with lower hospital costs, according to a new study published in the Journal of Clinical Oncology.
NIH/National Cancer Institute, NIH/National Institute for Nursing Research

Contact: Lauren Rankin
lauren.rankin@mssm.edu
212-201-2671
Center to Advance Palliative Care (CAPC)

Public Release: 8-Jun-2015
Journal of Molecular Diagnostics
Genomic testing can help identify patients at heightened risk for esophageal cancer
Barrett's esophagus (BE) develops in a subset of patients with gastroesophageal reflux disease and can increase the risk of developing cancer of the esophagus. Although periodic surveillance for cancer is recommended for BE patients, these examinations may fail to identify pre-cancerous dysplasia and early cancers. A report in the Journal of Molecular Diagnostics describes a test using next-generation sequencing to detect genomic mutations in precancerous esophageal tissue, which may improve cancer surveillance and early detection in patients with BE.
University of Pennsylvania, Columbia University, BETRNET Consortium, National Institutes of Health

Contact: Eileen Leahy
jmdmedia@elsevier.com
732-238-3628
Elsevier Health Sciences

Public Release: 8-Jun-2015
SNMMI 2015 Annual Meeting
Theranostic drug personalizes prostate cancer imaging and therapy
A novel radionuclide drug tackles the challenge of prostate cancer imaging and takes a turn as a cancer-killing therapy for tumors in and out of the prostate, according to research presented during the 2015 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI).
Helmholtz International Graduate School for Cancer Research, German Research Foundation, Klaus Tschira Foundation

Contact: Laurie Callahan
lcallahan@snmmi.org
703-652-6773
Society of Nuclear Medicine

Public Release: 8-Jun-2015
Proceedings of the National Academy of Sciences
Scientists show antitumor agent can be activated by natural response to cell stress
Scientists from the Florida campus of The Scripps Research Institute have found that a drug candidate with anticancer potential can be activated by one of the body's natural responses to cellular stress. Once activated, the agent can kill prostate cancer cells.
National Institutes of Health

Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute

Public Release: 8-Jun-2015
Nature Communications
Bacterial sepsis protein may inhibit cancer cell growth
A toxin secreted by Vibrio vulnificus, a water and food-borne bacteria that can cause rapidly lethal infections in persons with liver disease, has potential to prevent the growth of tumors.
National Institutes of Health

Contact: Marla Paul
marla-paul@northwestern.edu
312-503-8928
Northwestern University

Public Release: 8-Jun-2015
Development
Researchers identify unique marker on mom's chromosomes in early embryo
Researchers in the University of Georgia's Regenerative Bioscience Center are visually capturing the first process of chromosome alignment and separation at the beginning of mouse development. The findings could lead to answers to questions concerning the mechanisms leading to birth defects and chromosome instability in cancer cells. 'We've generated a model that is unique in the world,' said Rabindranath De La Fuente, an associate professor in the UGA College of Veterinary Medicine.
NIH/National Institute of Child Health and Human Development, Georgia Cancer Coalition, National Institutes of Health

Contact: Charlene Betourney
cbetourney@uga.edu
706-542-4081
University of Georgia

Public Release: 8-Jun-2015
Proceedings of the National Academy of Sciences
Yin and yang -- immune signaling protein has opposing roles in breast cancer development
Countering previously held beliefs, researchers at The University of Texas MD Anderson Cancer Center have discovered that inhibiting the immune receptor protein TLR4 may not be a wise treatment strategy in all cancers.

Contact: Clayton R. Boldt, Ph.D.
crboldt@mdanderson.org
713-792-9518
University of Texas M. D. Anderson Cancer Center

Public Release: 8-Jun-2015
Biology of Blood & Marrow Transplantation
Massey researchers identify patients at risk for stem cell transplant complications
Researchers at VCU Massey Cancer Center's Bone Marrow Transplant Program have recently published findings from a phase 2 clinical trial that demonstrate lymphocyte recovery in related and unrelated stem cell transplant recipients generally falls into three patterns that are significantly associated with survival. This first-of-its-kind research continues the efforts of principal investigator Amir Toor, M.D., to understand the immune system as a dynamical system that can be modeled to improve stem cell transplantation.
Sanofi-Aventis, VCU Massey Cancer Center, Commonwealth Health Research Board

Contact: John Wallace
wallacej@vcu.edu
804-628-1550
Virginia Commonwealth University

Public Release: 8-Jun-2015
Journal of Clinical Oncology
Important new research on early palliative care for advanced cancer patients published
Researchers at Trinity College Dublin and Mount Sinai in New York have just published new research which for the first time provides strong evidence on the economic benefits of early palliative care intervention for people with an advanced cancer diagnosis. Their findings were published today in the highly esteemed international peer-reviewed Journal of Clinical Oncology.

Contact: Yolanda Kennedy
yokenned@tcd.ie
353-189-63551
Trinity College Dublin

Public Release: 8-Jun-2015
Journal of Clinical Oncology
Certain donors with high T cell counts make better match for stem-cell transplant patients
Older patients who received stem cells from younger, unrelated donors with higher numbers of so-called killer T cells (CD8 cells) had significantly reduced risk of disease relapse and improved survival compared to those who received stem-cells from donors with low numbers of CD8 cells, including older matched siblings.
NIH/National Cancer Institute, Conquer Cancer Foundation, The National Marrow Donor Program, Commonwealth of Pennsylvania/CURE Grant

Contact: Steve Graff
stephen.graff@uphs.upenn.edu
215-349-5653
University of Pennsylvania School of Medicine

Public Release: 8-Jun-2015
Journal of Experimental Medicine
Breast cancer study raises hope of therapy to stop tumor spread
Scientists have discovered a trigger that allows breast cancer cells to spread to the lungs. The findings could lead to new therapies that stop the progression of breast cancer, the researchers at the University of Edinburgh say.

Contact: Jen Middleton
jen.middleton@ed.ac.uk
44-131-650-6514
University of Edinburgh

Showing releases 126-150 out of 1357.

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