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Showing releases 126-150 out of 1198.

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Public Release: 30-Apr-2013
mBio
Protein improves efficacy of tumor-killing enzyme
Scientists have devised a method for delivering tumor cell-killing enzymes in a way that protects the enzyme until it can do its work inside the cell. In their study in mBio®, the online open-access journal of the American Society for Microbiology, researchers assembled microscopic protein packages that can deliver an enzyme called PEIII to the insides of cells.

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology

Public Release: 30-Apr-2013
PLOS Medicine
Upper GI bleed linked to death from other causes
Individuals who have experienced a major bleed from their stomach or oesophagus (known as an upper gastrointestinal bleed) may be more likely to die from other causes, particularly malignant tumours and cardiovascular disease, than those without an upper gastrointestinal bleed, according to a study by UK researchers published in this week's PLOS Medicine.
Medical Research Council Population Health Scientist, University of Nottingham

Contact: Fiona Godwin
fgodwin@plos.org
01-223-442-834
Public Library of Science

Public Release: 30-Apr-2013
Cancer Epidemiology, Biomarkers & Prevention
Women smokers may have greater risk for colon cancer than men
Smokers of both genders had increased risk for colon cancer compared with never smokers. The risk increase was greater for female smokers. The more and longer a woman smoked the greater her risk.

Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research

Public Release: 30-Apr-2013
JAMA Media Briefing on Child Health
JAMA
Study compares effectiveness of 2 vs. 3 doses of HPV vaccine for girls and young women
With the number of doses and cost of human papillomavirus (HPV) vaccines a barrier to global implementation, researchers have found that girls who received two doses of HPV vaccine had immune responses to HPV-16 and HPV-18 infection that were noninferior to (not worse than) the responses for young women who received three doses, according to a study in the May 1 issue of JAMA, a theme issue on child health.

Contact: Brian Lin
brian.lin@ubc.ca
604-822-2234
The JAMA Network Journals

Public Release: 29-Apr-2013
International Journal of Cancer
Postcode inequality for cancer diagnosis 'costs lives'
Study finds hundreds of lives could be prolonged if women in poorer areas were diagnosed with breast cancer at same stage as those in affluent areas.
Cancer Research UK, National Institute for Health Research

Contact: Mark Rutherford
mark.rutherford@le.ac.uk
44-011-622-97292
University of Leicester

Public Release: 29-Apr-2013
JAMA Internal Medicine
Cancer studies often lack necessary rigor to answer key questions
Fueled in part by an inclination to speed new treatments to patients, research studies for cancer therapies tend to be smaller and less robust than for other diseases.
Food and Drug Administration

Contact: Sarah Avery
sarah.avery@duke.edu
919-660-1306
Duke University Medical Center

Public Release: 29-Apr-2013
Proceedings of the National Academy of Sciences
Big data analysis identifies prognostic RNA markers in a common form of breast cancer
An analysis that integrates three large sets of genomic data available through The Cancer Genome Atlas has identified 37 RNA molecules that might predict survival in patients with the most common form of breast cancer. The study analyzed large masses of data from 466 cases of the most common type of breast cancer and provides the first prognostic signature in cancer composed of both mRNA and microRNA.
NIH/National Cancer Institute, Italian Association for Cancer Research

Contact: Darrell E. Ward
darrell.ward@osumc.edu
614-293-3737
Ohio State University Medical Center

Public Release: 29-Apr-2013
JAMA Internal Medicine
Surgery for nonfatal skin cancers might not be best for elderly patients
Surgery is often recommended for skin cancers, but older, sicker patients can endure complications as a result and may not live long enough to benefit from the treatment.
NIH/National Center for Research Resources, NIH/National Institute of Arthritis and Musculoskeletal and Skin

Contact: Elizabeth Fernandez
elizabeth.fernandez@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 29-Apr-2013
PLOS ONE
Team finds markers related to ovarian cancer survival and recurrence
Illinois animal sciences professor Sandra Rodriguez-Zas and graduate student Kristin Delfino identified biomarkers that are used to determine ovarian cancer survival and recurrence and showed how the interactions between these biomarkers affect these outcomes.

Contact: Chelsey B. Coombs
diya@illinois.edu
217-333-5802
University of Illinois at Urbana-Champaign

Public Release: 29-Apr-2013
BMC Radiation Oncology
VEGF may not be relevant biomarker for advanced prostate cancer
The well-studied protein VEGF does not appear to have any prognostic or predictive value for men with locally advanced prostate cancer, researchers from the Department of Radiation Oncology at Thomas Jefferson University Hospital and other institutions found in a retrospective study published online April 25 in the journal BMC Radiation Oncology.

Contact: Danielle Servetnick
danielle.servetnick@jefferson.edu
215-955-2238
Thomas Jefferson University

Public Release: 29-Apr-2013
Journal of General Physiology
Food dye could provide 'blueprint' for treatment of Panx1-related diseases
The food dye Brilliant Blue FCF could be a useful tool in the development of treatments for a variety of conditions involving the membrane channel protein Pannexin 1, according to a study in the Journal of General.

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press

Public Release: 28-Apr-2013
Nature Structural & Molecular Biology
Mapping of cancer cell fuel pumps paves the way for new drugs
For the first time, researchers at Karolinska Institutet in Sweden have managed to obtain detailed images of the way in which the transport protein GLUT transports sugars into cells. The researchers are hoping that the study, published in the scientific magazine Nature Structural & Molecular Biology, will form the basis for new strategies to fight cancer cells.
Swedish Research Council, Swedish Cancer Society

Contact: Karolinska Institutet Press Office
pressinfo@ki.se
46-852-486-077
Karolinska Institutet

Public Release: 28-Apr-2013
Breast Cancer Research
How does pregnancy reduce breast cancer risk?
Being pregnant while young is known to protect a women against breast cancer. But why? Research in BioMed Central's open access journal Breast Cancer Research finds that Wnt/Notch signalling ratio is decreased in the breast tissue of mice which have given birth, compared to virgin mice of the same age.

Contact: Hilary Glover
hilary.glover@biomedcentral.com
44-020-319-22370
BioMed Central

Public Release: 26-Apr-2013
International Liver Congress 2013
Cardio could hold key to cancer cure
Regular exercise has been proven to reduce the chance of developing liver cancer in a world-first mice study that carries hope for patients at risk from hepatocellular carcinoma.

Contact: Dimple Natali
easlpressoffice@cohnwolfe.com
44-079-001-38904
European Association for the Study of the Liver

Public Release: 26-Apr-2013
International Liver Congress 2013
Novel screening tests for liver cancer
New data from two clinical trials presented today at the International Liver Congress™ 2013 demonstrate substantial improvements in the detection of both hepatocellular carcinoma and cholangiocarcinoma using diagnostic urine tests.

Contact: Dimple Natali
easlpressoffice@cohnwolfe.com
44-790-013-8904
European Association for the Study of the Liver

Public Release: 26-Apr-2013
International Liver Congress 2013
Developments in TACE and SIRT treatment in patients
Data from a number of clinical trials presented today at the International Liver Congress™ 2013 shed new light on the use of TACE and SIRT in the treatment of hepatocellular carcinoma.

Contact: Dimple Natali
easlpressoffice@cohnwolfe.com
44-079-001-38904
European Association for the Study of the Liver

Public Release: 26-Apr-2013
Scientific Reports
Battery of tests on cancer cells shows them as 'squishy,' yet tactically strong
A team of student researchers and their professors from 20 laboratories around the country have gotten a new view of cancer cells. The work could shed light on the transforming physical properties of these cells as they metastasize, said Jack R. Staunton, a Ph.D. candidate at Arizona State University in the lab of Prof. Robert Ros, and the lead author of a paper reporting on the topic.

Contact: Skip Derra
skip.derra@asu.edu
480-965-4823
Arizona State University

Public Release: 26-Apr-2013
Journal of Oncology Navigation and Survivorship
GW Cancer Institute publishes research on challenges faced by adolescent cancer survivors
New research out of the George Washington University Cancer Institute focuses on the difficulties of transitioning to adulthood while dealing with the long-term and late effects of cancer and its treatment. The study was recently published in the Journal of Oncology Navigation and Survivorship, titled "Improving Cancer Survivorship for Adolescents and Adults."

Contact: Lisa Anderson
lisama2@gwu.edu
202-994-3121
George Washington University

Public Release: 26-Apr-2013
Nature Scientific Reports
Physicists, biologists unite to expose how cancer spreads
A multi-institutional study including researchers from Princeton University's Physical Sciences-Oncology Center found that cancer cells that can break out of a tumor and invade other organs are more aggressive and nimble than nonmalignant cells.

Contact: Morgan Kelly
mgnkelly@princeton.edu
609-258-5729
Princeton University

Public Release: 25-Apr-2013
Chemical Communications
Virginia Tech Carilion scientists image nanoparticles in action
Scientists at the Virginia Tech Carilion Research Institute invented a technique for imaging nanoparticle dynamics with atomic resolution as these dynamics occur in a liquid environment. The results will allow, for the first time, the imaging of nanoscale processes, such as the engulfment of nanoparticles into cells.

Contact: Paula Byron
paulabyron@vt.edu
540-526-2027
Virginia Tech

Public Release: 25-Apr-2013
Journal of Investigative Dermatology
BUSM study reveals novel mechanism by which UVA contributes to photoaging of skin
A study conducted by researchers at Boston University School of Medicine provides new evidence that longwave ultraviolet light induces a protein that could result in premature skin aging. The findings demonstrate that aspects of photoaging, the process of skin aging by chronic exposure to ultraviolet radiation, could be linked to genetic factors that accelerate the aging process when induced by the environment.

Contact: Jenny Eriksen
jenny.eriksen@bmc.org
617-638-6841
Boston University Medical Center

Public Release: 25-Apr-2013
Applied Physics Letters
New imaging technology could reveal cellular secrets
Researchers have married two biological imaging technologies, creating a new way to learn how good cells go bad.
National Institutes of Health

Contact: Emil Venere
venere@purdue.edu
765-494-4709
Purdue University

Public Release: 25-Apr-2013
Cell
UK study shows potential new way to detect colorectal and other cancers
A unique new study led by University of Kentucky Markey Cancer Center researchers Guo-Min Li and Libya Gu, in collaboration with Dr. Wei Yang at National Institutes of Health, reveals a novel mechanism explaining the previously unknown root cause of some forms of colorectal cancers.

Contact: Allison Perry
allison.perry@uky.edu
859-323-2399
University of Kentucky

Public Release: 25-Apr-2013
Cell
Scientists discover new way protein degradation is regulated
Researchers at The Rockefeller University and the Howard Hughes Medical Institute have identified the mechanism by which the cell's protein recycler, the proteasome, ramps up its activity to take care of unwanted and potentially toxic proteins. The finding, which has implications for treating muscle wasting neurodegeneration, also suggests that small molecule inhibitors of this mechanism may be clinically useful in treating multiple myeloma.
National Institutes of Health

Contact: Joseph Bonner
joseph.bonner@rockefeller.edu
212-327-8998
Rockefeller University

Public Release: 25-Apr-2013
Cell
Sunshine hormone, vitamin D, may offer hope for treating liver fibrosis
Liver fibrosis results from an excessive accumulation of tough, fibrous scar tissue and occurs in most types of chronic liver diseases. In industrialized countries, the main causes of liver injury leading to fibrosis include chronic hepatitis virus infection, excess alcohol consumption and, increasingly, nonalcoholic steatohepatitis.

Contact: Andy Hoang
AHoang@salk.edu
619-861-5811
Salk Institute

Showing releases 126-150 out of 1198.

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