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Showing releases 126-150 out of 1282.

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Public Release: 7-Jul-2014
Lancet Oncology
Concern at lack of teenage patients in cancer trials
Age limits on clinical trials need to be more flexible to allow more teenage cancer patients the chance to access new treatments, according to a report from the National Cancer Research Institute, published in the Lancet Oncology.
National Cancer Research Institute

Contact: Alan Worsley
Alan.Worsley@cancer.org.uk
020-346-98300
Cancer Research UK

Public Release: 7-Jul-2014
Nature Communications
Pseudogenes may provide clearer understanding of biomarkers
The results indicated that the science of pseudogene expression analysis may very well play a key role in explaining how cancer occurs by helping medical experts in the discovery of new biomarkers. The study's findings appear in today's issue of Nature Communications.

Contact: Ron Gilmore
rlgilmore1@mdanderson.org
713-745-1898
University of Texas M. D. Anderson Cancer Center

Public Release: 7-Jul-2014
Journal of Cell Biology
Blocking cells' movement to stop the spread of cancer
Insights into how cells move through the body could lead to innovative techniques to stop cancer cells from spreading and causing secondary tumours, finds according to new UCL research.
Medical Research Council, Biotechnology and Biological Sciences Research Council, Uehara Memorial Foundation, Asahi Glass Foundation, Royal Society & Wellcome Trust

Contact: Dr Rebecca Caygill
r.caygill@ucl.ac.uk
44-020-310-83846
University College London

Public Release: 7-Jul-2014
Proceedings of the National Academy of Sciences
UGA researchers use nanoparticles to enhance chemotherapy
University of Georgia researchers have developed a new formulation of cisplatin, a common chemotherapy drug, that significantly increases the drug's ability to target and destroy cancerous cells.
National Institutes of Health

Contact: Shanta Dhar
shanta@uga.edu
706-542-1012
University of Georgia

Public Release: 7-Jul-2014
Journal of Men's Health
Does cycling increase risk for erectile dysfunction, infertility, or prostate cancer?
Cycling is a popular activity that offers clear health benefits, but there is an ongoing controversy about whether men who ride have a higher risk of urogenital disorders such as erectile dysfunction, infertility, or prostate cancer.

Contact: Kathryn Ruehle
kruehle@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 7-Jul-2014
Nature Methods
DNA origami nano-tool provides important clue to cancer
Researchers at Karolinska Institutet in Sweden have headed a study that provides new knowledge about the EphA2 receptor, which is significant in several forms of cancer. This is important knowledge in itself -- but just as important is how this study, which is published in the highly respected journal Nature Methods, was conducted.
Swedish Research Council, VINNOVA, and others

Contact: Press Office
pressinfo@ki.se
46-852-486-077
Karolinska Institutet

Public Release: 7-Jul-2014
Oncology Nursing Forum
Support team aiding caregivers of cancer patients shows success, CWRU researchers report
Many caregivers of terminal cancer patients suffer depression and report regret and guilt from feeling they could have done more to eliminate side effects and relieve the pain. So researchers from the nursing school at Case Western Reserve University devised and tested an intervention that quickly integrates a cancer support team to guide caregivers and their patients through difficult end-of-life treatment and decisions.
NIH/National Institute of Nursing Research, NIH/National Cancer Institute

Contact: Susan Griffith
susan.griffith@case.edu
216-368-1004
Case Western Reserve University

Public Release: 7-Jul-2014
AAPA Conference 2014
GVSU researchers find moral beliefs barrier to HPV vaccine
A survey of first-year Grand Valley State University students showed the biggest barrier to receiving a Human Papillomavirus vaccine was moral or religious beliefs.

Contact: Michele Coffill
coffillm@gvsu.edu
616-331-2221
Grand Valley State University

Public Release: 7-Jul-2014
Journal of Exposure Science and Environmental Epidemiology
Infant toenails reveal in utero exposure to low-level arsenic, Dartmouth study finds
Infant toenails are a reliable way to estimate arsenic exposure before birth, a Dartmouth College study shows.

Contact: John Cramer
John.Cramer@Dartmouth.edu
603-646-9130
Dartmouth College

Public Release: 7-Jul-2014
Proceedings of the National Academy of Sciences
Study shows restored immunity for cancer-related fungal infections
A study at The University of Texas M.D. Anderson Cancer Center used the Sleeping Beauty gene transfer system to modify T cells in hopes of fighting major life-threatening infections caused by invasive Aspergillus fungus.

Contact: Ron Gilmore
rlgilmore1@mdanderson.org
713-745-1898
University of Texas M. D. Anderson Cancer Center

Public Release: 4-Jul-2014
Molecular Cancer Therapeutics
First cancer immunotherapy for dogs developed
Nearly every second dog develops cancer from the age of 10 years onward. A specific form of therapy by which antibodies inhibit tumor growth has not been available for animals so far. Scientists at the Messerli Research Institute of the Vetmeduni Vienna, the Medical University, and the University of Vienna have developed, for the first time, antibodies to treat cancer in dogs. The scientists published their research data in the journal Molecular Cancer Therapeutics.

Contact: Erika Jensen-Jarolim
erika.jensen-jarolim@vetmeduni.ac.at
43-120-577-2660
University of Veterinary Medicine -- Vienna

Public Release: 4-Jul-2014
Nature Communications
Scientists find important piece in the brain tumor puzzle
Scientists at the Montreal Neurological Institute and Hospital, McGill University and McGill University Health Centre have shown that a member of the protein family known as SUMO -- small ubiquitin-like modifier -- is a key to why tumor cells multiply uncontrollably, especially in the case of glioblastoma.

Contact: Anita Kar
anita.kar@mcgill.ca
514-398-3376
McGill University

Public Release: 3-Jul-2014
Human Molecular Genetics
A CNIO team reduces the size of the human genome to 19,000 genes
A study led by Alfonso Valencia and Michael Tress at the Spanish National Cancer Research Centre updates the number of human genes to 19,000; 1,700 fewer than the genes in the most recent annotation, and well below the initial estimations of 100,000 genes. The work, published in the journal Human Molecular Genetics, concludes that almost all of these genes have ancestors prior to the appearance of primates 50 million years ago.

Contact: Nuria Noriega
nnoriega@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)

Public Release: 3-Jul-2014
Cancer Cell
New study reveals how tumors remodel their surroundings to grow
Research identifies a mechanism in the tumor stroma that triggers an inflammatory response, promoting tumor growth and metastasis. The findings suggest a new approach to anti-cancer therapies that incorporates targets in the tumor microenvironment.

Contact: Susan Gammon
sgammon@sanfordburnham.org
858-795-5012
Sanford-Burnham Medical Research Institute

Public Release: 3-Jul-2014
Angewandte Chemie
Safer, cheaper building blocks for future anti-HIV and cancer drugs
A team of researchers from KU Leuven, in Belgium, has developed an economical, reliable and heavy metal-free chemical reaction that yields fully functional 1,2,3-triazoles. Triazoles are chemical compounds that can be used as building blocks for more complex chemical compounds, including pharmaceutical drugs.

Contact: Wim Dehaen
wim.dehaen@chem.kuleuven.be
32-163-27439
KU Leuven

Public Release: 3-Jul-2014
Cell Reports
NUS researchers discover novel protein complex with potential to combat gastric cancer
A team of scientists from the Cancer Science Institute of Singapore at the National University of Singapore discovered that a protein named IL23A is part of our stomach's defense against bacterial infection which leads to gastric cancer. This finding could potentially be used to combat the deadly disease.

Contact: Kimberley Wang
kimberley.wang@nus.edu.sg
National University of Singapore

Public Release: 3-Jul-2014
Cell
Sweet genes
A research team at the Faculty of Medicine & Dentistry at the University of Alberta have discovered a new way by which metabolism is linked to the regulation of DNA, the basis of our genetic code. The findings may have important implications for the understanding of many common diseases, including cancer.
Canadian Institutes for Health Research

Contact: Ross Neitz
rneitz@ualberta.ca
780-492-5986
University of Alberta Faculty of Medicine & Dentistry

Public Release: 3-Jul-2014
Cell Stem Cell
Biochemical cascade causes bone marrow inflammation, leading to serious blood disorders
Like a line of falling dominos, a cascade of molecular events in the bone marrow produces high levels of inflammation that disrupt normal blood formation and lead to potentially deadly disorders including leukemia, an Indiana University-led research team has reported.
National Institutes of Health

Contact: Eric Schoch
eschoch@iu.edu
316-274-8205
Indiana University

Public Release: 3-Jul-2014
Science
New discovery in living cell signaling
A breakthrough discovery into how living cells process and respond to chemical information could help advance the development of treatments for a large number of cancers and other cellular disorders that have been resistant to therapy.
National Institutes of Health

Contact: Lynn Yarris
lcyarris@lbl.gov
510-486-5375
DOE/Lawrence Berkeley National Laboratory

Public Release: 2-Jul-2014
JAMA Surgery
Rapid surgical innovation puts patients at risk for medical errors
Researchers at the University of California, San Diego School of Medicine have found that the risk of patient harm increased two-fold in 2006 -- the peak year that teaching hospitals nationwide embraced the pursuit of minimally invasive robotic surgery for prostate cancer. Results of the study are published in the July 2 online issue of JAMA Surgery.

Contact: Jackie Carr
jcarr@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 2-Jul-2014
eLife
Upending a cancer dogma
Researchers at the University of California, San Diego School of Medicine say a protein essential to regulating cell cycle progression -- the process of cell division and replication -- activates a key tumor suppressor, rather than inactivating it as previously thought.

Contact: Jackie Carr
jcarr@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 2-Jul-2014
PLOS ONE
Noninvasive advanced image analysis could lead to better patient care
Lung cancer patients could receive more precise treatment, and their progress could be better tracked, using a new high-tech method of non-invasive medical imaging analysis, according to a study published today by the journal PLOS ONE.
TGen Foundation, Scottsdale Healthcare Foundation, Flinn Foundation

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute

Public Release: 2-Jul-2014
Experimental Cell Research
Stem cell type resists chemotherapy drug
In lab tests, Brown University researchers have found that adipose-derived stem cells, which can generate bone tissue, appear resistant to the toxicity of the chemotherapy drug methotrexate, which degrades bone in patients such as kids suffering from acute lymphoblastic leukemia. The newly published findings are preliminary but more tests are planned.
National Insitutes of Health, National Science Foundation

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University

Public Release: 2-Jul-2014
Proceedings of the National Academy of Sciences
Purdue-designed tool helps guide brain cancer surgery
A tool to help brain surgeons test and more precisely remove cancerous tissue was successfully used during surgery. The mass spectrometry tool sprays a microscopic stream of charged solvent onto the tissue surface to gather information about its molecular makeup and produces a color-coded image that reveals the location, nature and concentration of tumor cells.
National Institutes of Health

Contact: Elizabeth K. Gardner
ekgardner@purdue.edu
765-494-2081
Purdue University

Public Release: 1-Jul-2014
Oncotarget
Biomarker predicts effectiveness of brain cancer treatment
Researchers at the University of California, San Diego School of Medicine have identified a new biomarker that predicts whether glioblastoma -- the most common form of primary brain cancer -- will respond to chemotherapy. The findings are published in the July print issue of Oncotarget.
Sontag Foundation, Burroughs Wellcome Foundation, Kimmel Foundation, Forbeck Foundation

Contact: Jackie Carr
jcarr@ucsd.edu
619-543-6163
University of California - San Diego

Showing releases 126-150 out of 1282.

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