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Showing releases 126-150 out of 1216.

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Public Release: 15-Jul-2013
Cancer Research
Scientists at NCI generate largest data set of cancer-related genetic variations
Scientists at the National Cancer Institute have generated a data set of cancer-specific genetic variations and are making these data available to the research community, according to a study published in Cancer Research, a journal of the American Association for Cancer Research.

Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research

Public Release: 15-Jul-2013
Annals of Internal Medicine
Annals of Internal Medicine tip sheet for July 16, 2013
Below is information about articles being published in the July 9 issue of Annals of Internal Medicine. The information is not intended to substitute for the full article as a source of information.

Contact: Megan Hanks
mhanks@acponline.org
215-351-2656
American College of Physicians

Public Release: 14-Jul-2013
Nature Genetics
NIH scientists find that proteins involved in immunity potentially cause cancer
A set of proteins involved in the body's natural defenses produces a large number of mutations in human DNA, according to a study led by researchers at the National Institutes of Health. The findings suggest that these naturally produced mutations are just as powerful as known cancer-causing agents in producing tumors.
NIH/National Institute of Environmental Health Sciences

Contact: Robin Arnette
arnetter@niehs.nih.gov
919-541-5143
NIH/National Institute of Environmental Health Sciences

Public Release: 14-Jul-2013
Nature Genetics
DNA abnormalities may contribute to cancer risk in people with type 2 diabetes
A type of genetic abnormality linked to cancer is more common in people with type 2 diabetes than the rest of the population, a new study has found.

Contact: Sam Wong
sam.wong@imperial.ac.uk
44-207-594-2198
Imperial College London

Public Release: 14-Jul-2013
Nature Genetics
Antiviral enzyme contributes to several forms of cancer, University of Minnesota researchers say
Researchers at the University of Minnesota have discovered that a human antiviral enzyme causes DNA mutations that lead to several forms of cancer.

Contact: Peggy Rinard
rinar001@umn.edu
612-624-0774
University of Minnesota

Public Release: 14-Jul-2013
Nature Structural & Molecular Biology
Key step in molecular 'dance' that duplicates DNA deciphered
Scientists have captured new details of the biochemical interactions necessary for cell division -- molecular images showing how the enzyme that unwinds the DNA double helix gets drawn to and wrapped around its target. The research may suggest ways for stopping cell division when it goes awry.
National Institutes of Health, UK Medical Research Council, Japan Society for Promotion of Science, Uehara Memorial Foundation

Contact: Karen McNulty Walsh
kmcnulty@bnl.gov
631-344-8350
DOE/Brookhaven National Laboratory

Public Release: 14-Jul-2013
Nature Immunology
Scientists discover kill-switch controls immune-suppressing cells
Scientists have uncovered the mechanism that controls whether cells that are able to suppress immune responses live or die. The discovery of the cell death processes that determine the number of 'regulatory T cells' an individual has could one day lead to better treatments for immune disorders.
National Health and Medical Research Council, Victorian Government, European Union, Belgian Government, Flanders Institute for Biotechnology

Contact: Liz Williams
williams@wehi.edu.au
61-428-034-089
Walter and Eliza Hall Institute

Public Release: 12-Jul-2013
Lancet Oncology
Study finds strong pregnancy outcomes for survivors of childhood cancer
New research finds that almost two-thirds of female childhood cancer survivors who tried at least a year to get pregnant eventually conceive.
NIH/National Cancer Institute, Swim Across America

Contact: Irene Sege
irene.sege@childrens.harvard.edu
617-919-7379
Dana-Farber Cancer Institute

Public Release: 12-Jul-2013
American Journal of Public Health
Research finds racial/ethnic disparities in health care among older male cancer survivors
Older African-American and Hispanic men who have survived cancer are less likely than their white counterparts to see a specialist or receive basic preventive care, such as vaccinations, according to new research from Wake Forest Baptist Medical Center.
NIH/National Cancer Institute

Contact: Bonnie Davis
bdavis@wakehealth.edu
336-726-4977
Wake Forest Baptist Medical Center

Public Release: 11-Jul-2013
Environmental Research Letters
Researchers estimate over 2 million deaths annually from air pollution
Over two million deaths occur each year as a direct result of human-caused outdoor air pollution, a new study has found.

Contact: Michael Bishop
michael.bishop@iop.org
01-179-301-032
Institute of Physics

Public Release: 11-Jul-2013
Cancer Cell
Important advance in the fight against skin cancer
Researchers from the Hospital del Mar Medical Research Institute, lead by Lluís Espinosa, have identified a new function of the IB protein that is key in the development of squamous-cell carcinoma, a type of skin cancer. The study has been published in the prestigious journal Cancer Cell and provides a new tool for the diagnosis of the disease and, in the future, will enable the identification of novel therapeutic targets to treat this type of cancer.

Contact: Marta Calsina
mcalsina@imim.es
34-933-160-680
IMIM (Hospital del Mar Medical Research Institute)

Public Release: 11-Jul-2013
Molecular Cell
Critical pathway in cell cycle may lead to cancer development
A team of scientists at the Salk Institute for Biological Studies has identified why disruption of a vital pathway in cell cycle control leads to the proliferation of cancer cells. Their findings on telomeres, the stretches of DNA at the ends of chromosomes that protect our genetic code and make it possible for cells to divide, suggest a potential target for preventive measures against cancer, aging and other diseases. The findings were published July 11 in Molecular Cell.

Contact: Kat Kearney
kkearney@salk.edu
858-453-4100
Salk Institute

Public Release: 11-Jul-2013
Developmental Cell
Hippo pathway to better cancer treatment?
Researchers at the University of British Columbia have discovered a potential new pathway to treat cancer by asking some odd questions about the size of animals.

Contact: Corey Allen
corey.allen@ubc.ca
604-822-2644
University of British Columbia

Public Release: 11-Jul-2013
Science
Nerves play key role in triggering prostate cancer and influencing its spread
Researchers at Albert Einstein College of Medicine of Yeshiva University have found that nerves play a critical role in both the development and spread of prostate tumors. Their findings, using both a mouse model and human prostate tissue, may lead to new ways to predict the aggressiveness of prostate cancer and to novel therapies for preventing and treating the disease. The study published online today in the July 12 edition of Science.
US Department of Defense

Contact: Deirdre Branley
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine

Public Release: 11-Jul-2013
Journal of Clinical Investigation
Clinical trial assesses anti-melanoma vaccine's ability to induce an anti-cancer immune response
In the current issue of the Journal of Clinical Investigation, Dr. Beatriz Carreno and colleagues at Washington University report the results of a clinical trial that tested a vaccine to treat newly diagnosed advanced melanoma.
Barnes-Jewish Hospital Foundation, Siteman Cancer Frontier Fund, Washington University

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 11-Jul-2013
Journal of Biological Chemistry
Molecular discovery puts cancer treatment in a new perspective
Researchers from the University of Copenhagen and the National Institutes of Health have obtained ground-breaking new knowledge about proteases - important enzymes which, among other things, play a role in the development of cancer cells. The findings may be significant for the development of cancer drugs, and have just been published in Journal of Biological Chemistry.

Contact: Stine Friis
sfriis@sund.ku.dk
240-645-5207
University of Copenhagen

Public Release: 11-Jul-2013
Clinical Cancer Research
New hope in the fight against childhood cancer
Cancer Research UK scientists at the University of Southampton are seeing positive results in a pre-clinical trial that could bring treatments for a particular aggressive form of childhood cancer closer to reality.

Contact: Becky Attwood
r.attwood@soton.ac.uk
44-023-805-95457
University of Southampton

Public Release: 11-Jul-2013
International Journal of Cancer
Metastatic pancreatic, primary breast cancer have common growth mechanisms, study suggests
A recently discovered form of the protein that triggers blood clotting plays a critical role in promoting the growth of metastatic pancreatic cancer and primary breast cancer, according to the cumulative findings from two new scientific manuscripts published online ahead of print in the International Journal of Cancer and PNAS.
NIH/National Cancer Institute, Netherlands Organization for Scientific Research

Contact: Amanda Harper
amanda.harper@uc.edu
513-558-4657
University of Cincinnati Academic Health Center

Public Release: 11-Jul-2013
Physics World
New theory uncovers cancer's deep evolutionary roots
A new way to look at cancer -- by tracing its deep evolutionary roots to the dawn of multicellularity more than a billion years ago -- has been proposed by Paul Davies of Arizona State University in collaboration with Charles Lineweaver of the Australian National University. If their theory is correct, it promises to transform the approach to cancer therapy, and to link the origin of cancer to the origin of life and the developmental processes of embryos.
NIH/National Cancer Institute

Contact: Skip Derra
skip.derra@asu.edu
480-965-4823
Arizona State University

Public Release: 11-Jul-2013
Cell
Scientists develop ground-breaking new method of 'starving' cancer cells
A University of Southampton Professor, in collaboration with colleagues at the BC Cancer Agency Research Centre, have discovered a novel way of killing cancer cells.

Contact: Charlotte Woods
c.woods@soton.ac.uk
0238-059-2128
University of Southampton

Public Release: 11-Jul-2013
Aflibercept in colorectal cancer: Indication of minor added benefit
Aflibercept prolongs overall survival in certain patients with colorectal cancer, but also has more severe side effects than comparator therapy.

Contact: IQWiG
presse@iqwig.de
49-022-135-6850
Institute for Quality and Efficiency in Health Care

Public Release: 10-Jul-2013
Cancer Epidemiology, Biomarkers & Prevention
Factors influencing delay in breast cancer treatment differ for African-American and white women
A study using data from the Carolina Breast Cancer Study Phase III, a program of UNC Lineberger Comprehensive Cancer Center, found that among White women, household size and losing a job due to one's diagnosis were reasons for delay in treatment, while among African-American women, the type of treatment received influenced delay.
University Cancer Research Fund of North Carolina, NIH/National Cancer Institute Specialized Program

Contact: Dianne Shaw
dgs@med.unc.edu
919-966-7834
University of North Carolina Health Care

Public Release: 10-Jul-2013
Journal of the American Chemical Society
Researchers perform DNA computation in living cells
Chemists from North Carolina State University have performed a DNA-based logic-gate operation within a human cell. The research may pave the way to more complicated computations in live cells, as well as new methods of disease detection and treatment.
American Chemical Society, American Cancer Society

Contact: Tracey Peake
tracey_peake@ncsu.edu
919-515-6142
North Carolina State University

Public Release: 10-Jul-2013
Genes & Development
Protein targeted for cancer drug development is essential for normal heart function
St. Jude Children's Research Hospital scientists have discovered that a protein used by cancer cells to evade death also plays a vital role in heart health.
NIH/National Cancer Institute, National Institutes of Health, National Cancer Society, American-Lebanese-Syrian Associated Charities

Contact: Summer Freeman
summer.freeman@stjude.org
901-595-3061
St. Jude Children's Research Hospital

Public Release: 10-Jul-2013
Nature Methods
Memorial Sloan-Kettering researchers develop new method for tracking cell signaling
Researchers at Memorial Sloan-Kettering Cancer Center have developed a new method for identifying the cell of origin of intracellular and secreted proteins within multicellular environments.
NIH/National Cancer Institute

Contact: Caitlin Hool
hoolc@mskcc.org
212-639-3573
Memorial Sloan-Kettering Cancer Center

Showing releases 126-150 out of 1216.

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