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Showing releases 126-150 out of 1191.

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Public Release: 5-Jan-2015
Cell Reports
The bowhead whale lives over 200 years. Can its genes tell us why?
A whale that can live over 200 years with little evidence of age-related disease may provide untapped insights into how to live a long and healthy life. In the Jan. 6 issue of Cell Reports, researchers present the complete bowhead whale genome and identify key differences compared to other mammals. Alterations in bowhead genes related to cell division, DNA repair, cancer, and aging may have helped increase its longevity and cancer resistance.

Contact: Joseph Caputo
Cell Press

Public Release: 5-Jan-2015
Cell Reports
Scientists sequence genome of longest-lived mammal
Scientists at the University of Liverpool have sequenced the genome of the bowhead whale, estimated to live for more than 200 years with low incidence of disease.

Contact: Samantha Martin
University of Liverpool

Public Release: 5-Jan-2015
Journal of Clinical Oncology
Radiation plus hormone therapy prolongs survival for older men with prostate cancer
Adding radiation treatment to hormone therapy saves more lives among older men with locally advanced prostate therapy than hormone therapy alone, according to a new study in the Journal of Clinical Oncology this week from Penn Medicine researchers.
NIH/National Cancer Institute, American Cancer Society

Contact: Steve Graff
University of Pennsylvania School of Medicine

Public Release: 5-Jan-2015
American Journal of Preventive Medicine
Rotating night shift work can be hazardous to your health
In a study in the American Journal of Preventive Medicine, researchers found that women working rotating night shifts for five or more years appeared to have a modest increase in all-cause and CVD mortality and those working 15 or more years of rotating night shift work appeared to have a modest increase in lung cancer mortality. These results add to prior evidence of a potentially detrimental effect of rotating night shift work on health and longevity.

Contact: Angela J. Beck
Elsevier Health Sciences

Public Release: 1-Jan-2015
'Bad luck' of random mutations plays predominant role in cancer, study shows
Scientists from the Johns Hopkins Kimmel Cancer Center have created a statistical model that measures the proportion of cancer incidence, across many tissue types, caused mainly by random mutations that occur when stem cells divide. By their measure, two-thirds of adult cancer incidence across tissues can be explained primarily by 'bad luck,' when these random mutations occur in genes that can drive cancer growth, while the remaining third are due to environmental factors and inherited genes.
Virginia and D. K. Ludwig Fund for Cancer Research, Lustgarten Foundation for Pancreatic Cancer Research, Sol Goldman Pancreatic Cancer Research Center, NIH/National Cancer Institute

Contact: Vanessa Wasta
Johns Hopkins Medicine

Public Release: 1-Jan-2015
Cancer Discovery
Researchers target the cell's 'biological clock' in promising new therapy to kill cancer cells
Cell biologists at UT Southwestern Medical Center have targeted telomeres with a small molecule called 6-thiodG that takes advantage of the cell's 'biological clock' to kill cancer cells and shrink tumor growth.

Contact: Russell Rian
UT Southwestern Medical Center

Public Release: 1-Jan-2015
Analytica Chimica Acta
More efficient, sensitive estrogen detection developed at UT Arlington
UT Arlington scientists working in the Shimadzu Institute for Research Technologies have developed a new method for detecting trace amounts of estrogen, an advance that will help health researchers.

Contact: Traci Peterson
University of Texas at Arlington

Public Release: 31-Dec-2014
3-D culture system for pancreatic cancer has potential to change therapeutic approaches
Pancreatic cancer is one of the most deadly forms of cancer, with only 6 percent of patients surviving five years after diagnosis. Today, CSHL and The Lustgarten Foundation announce the development of a new model system to grow both normal and cancerous pancreatic cells in the laboratory. Their work promises to change the way pancreatic cancer research is done, allowing scientists to interrogate the pathways driving this devastating disease while searching for new drug targets.
Lustgarten Foundation for Pancreatic Cancer Research, Cold Spring Harbor Laboratory Association, NIH/National Cancer Institute Center for Cancer Genomics, Carcinoid Foundation, PCUK, David Rubinstein Center for Pancreatic Cancer Research

Contact: Jaclyn Jansen
Cold Spring Harbor Laboratory

Public Release: 31-Dec-2014
New England Journal of Medicine
Mayo Clinic: Women with atypical hyperplasia are at higher risk of breast cancer
Women with atypical hyperplasia of the breast have a higher risk of developing breast cancer than previously thought, a Mayo Clinic study has found. Results of the study appear in a special report on breast cancer in the New England Journal of Medicine.
National Institutes of Health

Contact: Joe Dangor
Mayo Clinic

Public Release: 31-Dec-2014
CA: A Cancer Journal for Clinicians
More than 1.5 million cancer deaths averted during 2 decades of dropping mortality
The American Cancer Society's annual cancer statistics report finds that a 22 percent drop in cancer mortality over two decades led to the avoidance of more than 1.5 million cancer deaths that would have occurred if peak rates had persisted.
American Cancer Society

Contact: David Sampson
American Cancer Society

Public Release: 31-Dec-2014
Journal of Clinical Oncology
Stereotactic body radiation therapy plus chemotherapy improves survival among stage 4 lung cancer patients
A clinical trial that combined stereotactic body radiation therapy with a specific chemotherapy regimen more than doubled survival rates for certain stage 4 lung cancer patients.

Contact: Lori Sundeen Soderbergh
UT Southwestern Medical Center

Public Release: 30-Dec-2014
PLOS Medicine
Neonatal HBV vaccine reduces liver cancer risk
Neonatal HBV vaccination reduces the risk of liver cancer and other liver diseases in young adults in China, according to a study published by Chunfeng Qu, Taoyang Chen, Yawei Zhang and colleagues from the Cancer Institute & Hospital at the Chinese Academy of Medical Sciences, Qidong Liver Cancer Institute, China, and Yale School of Public Health and School of Medicine, USA in this week's PLOS Medicine.
State Key Projects Specialized on Infection Diseases, 973 Program Project of China, National Institutes of Health, 6th to 11th Key Technologies R&D Program of China

Contact: Maya Sandler

Public Release: 30-Dec-2014
American Journal of Roentgenology
Lung cancer metastases may travel through airways to adjacent or distant lung tissue
A new study by researchers in Canada supports the hypothesis that lung cancer, particularly adenocarcinoma, may spread through the airways. The putative occurrence of intrapulmonary aerogenous metastasis of lung cancer has staging, management, and prognostic implications.

Contact: Lissa D. Hurwitz
American Roentgen Ray Society

Public Release: 30-Dec-2014
Proceedings of the National Academy of Sciences
Cancer treatment potential discovered in gene repair mechanism
Case Western Reserve researchers have identified a two-pronged therapeutic approach that shows great potential for weakening and then defeating cancer cells. The team's complex mix of genetic and biochemical experiments unearthed a way to increase the presence of a tumor-suppressing protein which, in turn, gives it the strength to direct cancer cells toward a path that leads to their destruction. The breakthrough detailed appeared in the Nov. 24 online edition of the journal PNAS.
National Institutes of Health, National Center for Advancing Translational Sciences, Clinical and Translational Collaborative of Cleveland

Contact: Jeannette Spalding
Case Western Reserve University

Public Release: 29-Dec-2014
Proceedings of the National Academy of Sciences
Sugar molecule links red meat consumption and elevated cancer risk in mice
While people who eat a lot of red meat are known to be at higher risk for certain cancers, other carnivores are not, prompting researchers at the University of California, San Diego School of Medicine to investigate the possible tumor-forming role of a sugar called Neu5Gc, which is naturally found in most mammals but not in humans.
Ellison Medical Foundation, NIH/National Cancer Institute, Samuel and Ruth Engelberg Fellowship from the Cancer Research Institute, Swiss National Science Foundation

Contact: Scott LaFee
University of California - San Diego

Public Release: 29-Dec-2014
Stem Cells
Reprogramming stem cells may prevent cancer after radiation
University of Colorado Cancer Center study published today in Stem Cells shows that pre-programmed stem cell death allows cancer to grow after full-body irradiation, and that NOTCH signaling may restore stem cell function, protecting against cancer after radiation.
National Institutes of Health, Leukemia and Lymphoma Society

Contact: Garth Sundem
University of Colorado Denver

Public Release: 29-Dec-2014
Protein ID'd as possible universal therapeutic target for many infections, including Ebola
A protein called GRP78 could be a universal therapeutic target for treating human diseases like brain cancer, Ebola, influenza, hepatitis and superbug bacteria such as methicillin-resistant Staphylococcus epidermidis and methicillin-resistant Staphylococcus aureus, according to a Virginia Commonwealth University-led preclinical study published this month in the Journal of Cellular Physiology.
National Institutes of Health, Virginia Commonwealth University

Contact: Brian McNeill
Virginia Commonwealth University

Public Release: 29-Dec-2014
Cancer Discovery
Cancer-causing mutation discovered in 1982 finally target of clinical trials
A recent article in the journal Cancer Discovery describes clinical trials at the University of Colorado Cancer Center and elsewhere that match drugs to long-overlooked oncogene, TRK, offering targeted treatment options for cancers that harbor these gene abnormalities.
V Foundation, National Institutes of Health, National Cancer Institute

Contact: Garth Sundem
University of Colorado Denver

Public Release: 29-Dec-2014
Proceedings of the National Academy of Sciences
Tracing evolution of chicken flu virus yields insight into origins of deadly H7N9 strain
An international research team has shown how changes in a flu virus that has plagued Chinese poultry farms for decades helped create the novel avian H7N9 influenza A virus that has sickened more than 375 people since 2013. The research appears in the current online early edition of the scientific journal Proceedings of the National Academy of Sciences.
National Natural Science Foundation of China, National Basic Research Program, China Scholarship Foundation, Key Technologies Research & Development Program of China, China Agriculture Research System, NIH/National Institute of Allergy and Infectious Dise

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Public Release: 29-Dec-2014
Plastic and Reconstructive Surgery
Breast reconstruction using patient's own tissues yield higher satisfaction rates
For women who have undergone mastectomy, breast reconstruction using the patient's own tissues -- rather than implants -- provides higher satisfaction scores, reports a study in the January issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

Contact: Connie Hughes
Wolters Kluwer Health

Public Release: 24-Dec-2014
Cell Reports
Scientists zero in on how lung cancer spreads
Cancer Research UK scientists have taken microscopic images revealing that the protein ties tethering cells together are severed in lung cancer cells.

Contact: Emily Head
Cancer Research UK

Public Release: 24-Dec-2014
Nature Communications
Scientists identify rare cancer's genetic pathway
An international research team, including four Simon Fraser University scientists, has identified the 'mutational landscape' of intrahepatic cholangiocarcinoma, a rare, highly fatal form of liver cancer that disproportionately affects people in Asian countries.
Natural Sciences and Engineering Research Council

Contact: Jack Chen
Simon Fraser University

Public Release: 23-Dec-2014
Clinical Cancer Research
Armed virus shows promise as treatment for pancreatic cancer
A new combination of two different approaches -- virotherapy and immunotherapy -- is showing 'great promise' as a treatment for pancreatic cancer, according to new research from Queen Mary University of London.
Pancreatic Cancer Research Fund

Contact: Maggie Blanks
Pancreatic Cancer Research Fund

Public Release: 23-Dec-2014
Researchers confirm whole-genome sequencing can successfully identify cancer-related mutations
UT Southwestern Medical Center cancer researchers have demonstrated that whole-genome sequencing can be used to identify patients' risk for hereditary cancer.

Contact: Lori Sundeen Soderbergh
UT Southwestern Medical Center

Public Release: 23-Dec-2014
Science Signaling
Researchers map paths to cancer drug resistance
A team of researchers led by Duke Cancer Institute has identified key events that prompt certain cancer cells to develop resistance to otherwise lethal therapies.
National Institutes of Health

Contact: Sarah Avery
Duke University Medical Center

Showing releases 126-150 out of 1191.

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