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Showing releases 126-150 out of 1352.

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Public Release: 13-May-2016
Frontiers in Genetics
Using precision-genetics in pigs to beat cancer
Because of their similarities to people, using new technology in pigs turn up as a valuable alternative to rodent models of cancer.
Recombinetics Inc.

Contact: Michelle Ponto
michelle.ponto@frontiersin.org
41-215-101-704
Frontiers

Public Release: 13-May-2016
Clinical Cancer Research
Researchers find blood marker that determines who will respond to colorectal cancer drug
Cancer researchers have identified a marker that shows up in a blood test that determines which patients with colorectal cancer that has spread would benefit from receiving the drug cetuximab.
Ontario Institute of Cancer Research, Alan B. Brown Chair in Molecular Genomics, Cancer Care Ontario Chair in Experimental Therapeutics and Population Studies, Canadian Cancer Society, Princess Margaret Cancer Foundation

Contact: Jane Finlayson
jane.finlayson@uhn.ca
416-946-2846
University Health Network

Public Release: 13-May-2016
Oncotarget
Gene mutation patterns in melanoma vary from North to South in New Zealand
Melanomas in patients from New Zealand's South Island are significantly more likely than those of North Islanders to carry a gene mutation that has implications for mutation-targeted drug therapies and for patient outcomes, new University of Otago-led research suggests.

Contact: Professor Michael Eccles
michael.eccles@otago.ac.nz
University of Otago

Public Release: 13-May-2016
Scientific Reports
Novel insight into interaction between discharge plasma and cells via TRP channel
Researchers have discovered that the short-lived reactive species generated by plasma can enhance the calcium ion influx into cells.

Contact: Toshiro Kaneko
kaneko@ecei.tohoku.ac.jp
Tohoku University

Public Release: 12-May-2016
JAMA Oncology
Is initiation of chemo affected by complementary, alternative medicine use?
Women with early-stage breast cancer for whom chemotherapy was indicated and who used dietary supplements and multiple types of complementary and alternative medicine (CAM) were less likely to start chemotherapy than nonusers of CAM, according to a new study published online by JAMA Oncology.

Contact: Stephanie Berger
sb2247@columbia.edu
212-305-4372
The JAMA Network Journals

Public Release: 12-May-2016
PLOS Genetics
Dogs provide information about brain tumor development in humans
Brain tumors in dogs are strikingly similar to their human tumor counterparts. In a recent study in the journal PLOS Genetics, researchers at Uppsala University and Swedish University of Agricultural Sciences have used genetic analyses in different dog breeds to identify genes that could have a role in the development of brain tumors in both dogs and human.

Contact: Karin Forsberg Nilsson
karin.nilsson@igp.uu.se
46-701-679-579
Uppsala University

Public Release: 12-May-2016
PLOS Genetics
Study of glioma susceptibility in dogs may yield insights for humans
A new study of the genetic factors underlying glioma formation in dogs may hold clues to how these common and often untreatable tumors form in humans. The genome study, which was conducted across 25 dog breeds, identified three genes associated with the tumor. The results from this research, led by Katarina Truvé of the Swedish University of Agricultural Sciences and Kerstin Lindblad-Toh of Uppsala University, were published on May 12 in PLOS Genetics.

Contact: Amy Yau
ayau@plos.org
44-012-234-42823
PLOS

Public Release: 12-May-2016
Nature Medicine
Andrei Goga's UCSF team finds new approaches to eradicate aggressive breast cancers
Dr. Goga's team identified fatty acid oxidation intermediates as being significantly upregulated in a MYC-driven model of TNBC. In the MYC-driven transgenic TNBC model and also MYC over-expressing TNBC PDX models, they found that inhibition of FAO decreased energy metabolism and blocked tumor growth, suggesting that FAO has a critical role for in vivo tumor activity.
Department of Defense, Congressionally Directed Medical Research Programs, Breast Cancer Research Program

Contact: Gail Whitehead
patricia.g.whitehead4.ctr@mail.mil
301-619-7783
US Department of Defense Congressionally Directed Medical Research Programs

Public Release: 12-May-2016
Cell
Mass. General study identifies potential treatment target for pancreatic cancer
Massachusetts General Hospital investigators have identified the first potential molecular treatment target for the most common form of pancreatic cancer, which kills more than 90 percent of patients.
National Institutes of Health

Contact: Katie Marquedant
kmarquedant@partners.org
617-726-0337
Massachusetts General Hospital

Public Release: 12-May-2016
Cell Reports
Stopping cancer in its tracks
Inhibiting autophagy, the process cells use to degrade large intra-cellular cargo, effectively blocks tumor cell migration and breast cancer metastasis in tumor models. Metastasis is responsible for 90 percent of cancer deaths. There are approved drugs that can disrupt autophagy.
NIH/National Cancer Institute

Contact: John Easton
john.easton@uchospitals.edu
773-795-5225
University of Chicago Medical Center

Public Release: 12-May-2016
Science
Scientists find that cancer can arise from changes in the proteins that package DNA
Mutations in histones, the proteins that shield and package DNA, have been linked to many types of cancer, but their role in promoting disease has not been clear. Now, for the first time, scientists have found that a change to the structure of a histone can trigger a tumor on its own.
The Rockefeller University, Wisconsin Institute for Discovery, The Greater Milwaukee Foundation, Starr Cancer Consortium, Sidney Kimmel Foundation, National Institutes of Health

Contact: Katherine Fenz
kfenz@rockefeller.edu
212-327-7913
Rockefeller University

Public Release: 12-May-2016
Science
Gene regulatory mutation linked to rare childhood cancer
A single defect in a gene that codes for a histone -- a 'spool' that wraps idle DNA -- is linked to pediatric cancers in a study published today in the journal Science. 'Unlike most cancers that require multiple hits, we found that this particular mutation can form a tumor all by itself,' says Peter W. Lewis, an assistant professor of biomolecular chemistry in the School of Medicine and Public Health at the University of Wisconsin-Madison.
National Institutes of Health

Contact: Peter W. Lewis
plewis@discovery.wisc.edu
608-316-4388
University of Wisconsin-Madison

Public Release: 12-May-2016
PLOS ONE
Cancer patients with depression 'struggle to get their lives back after treatment'
People with depression are significantly less likely to recover well after treatment for colorectal cancer compared to those without depression, according to new research by Macmillan Cancer Support and the University of Southampton.

Contact: Becky Attwood
r.attwood@soton.ac.uk
University of Southampton

Public Release: 12-May-2016
JAMA Ophthalmology
LSU Health New Orleans ophthalmologist recommends UV protection inside cars
In invited commentary on a comparative study of the protective properties of windshields and side-windows in cars against harmful UV rays, Dr. Jayne Weiss, Professor and Chair of Ophthalmology at LSU Health New Orleans School of Medicine, has a take-home message for both ophthalmologists and consumers -- UV protection should be used not just outdoors, but inside cars, too.
Research to Prevent Blindness, Lions Eye Foundation

Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Sciences Center

Public Release: 12-May-2016
JAMA Oncology
Use of complementary, alternative medicine affects initiation of chemotherapy
Women with early-stage breast cancer for whom chemotherapy was indicated and who used dietary supplements and multiple types of complementary and alternative medicine (CAM) were less likely to start chemotherapy than nonusers of alternative therapies, according to latest research at Columbia University's Mailman School of Public Health. This is one of the first studies to evaluate how complementary and alternative medicine use affects decisions regarding chemotherapy.
NIH/National Cancer Institute, US Department of Defense

Contact: Stephanie Berger
sb2247@columbia.edu
212-305-4372
Columbia University's Mailman School of Public Health

Public Release: 12-May-2016
European Journal of Surgical Oncology
Surgical oncology societies: Global curriculum to address training variations, inadequacies
The Society of Surgical Oncology and the European Society of Surgical Oncology, in two jointly published reports, highlight the global variations in training and make the case for a streamlined global surgical oncology curriculum of uniform standards. It is envisioned that the application of this minimum uniform standards of training will create a robust workforce of well-trained surgical oncologists to meet the growing need resulting from the rising global cancer burden.

Contact: Carine Lecoq
carine.lecoq@essoweb.org
32-253-73106
ECCO-the European CanCer Organisation

Public Release: 11-May-2016
Nature
UK study shows new potential marker for obesity
A new study led by University of Kentucky researchers and published in Nature shows a potential new biological marker for the development of obesity and a possible target for obesity prevention and treatment.

Contact: Allison Perry
allison.perry@uky.edu
859-323-2399
University of Kentucky

Public Release: 11-May-2016
CancerCare releases landmark patient access and engagement report
A landmark report illustrating the many physical, emotional, financial, practical and informational needs cancer patients experience during and after clinical treatment was released today by CancerCare, a national nonprofit organization that provides free psychosocial support, education and financial assistance to anyone affected by cancer.
AbbVie, Amgen, AstraZeneca, Bristol-Myers Squibb, Genentech, Helsinn Therapeutics, Gilead Sciences, Incyte Corporation, Janssen Oncology, Lilly, Merck, PhRMA, Pfizer

Contact: Ellen Sonet
esonet@cancercare.org
212-712-8351
CancerCare

Public Release: 11-May-2016
British Journal of Radiology
Prolonged breath holds of over five minutes could help in targeted radiotherapy
Researchers have successfully shown for the first time that breast cancer patients can be trained to achieve single prolonged breath holds of over five minutes, opening the door for targeted radiotherapy to be administered with just one dose in each daily session.

Contact: Luke Harrison
l.harrison.1@bham.ac.uk
University of Birmingham

Public Release: 11-May-2016
JAMA Dermatology
Ways to improve patient comfort during skin cancer screening
Pitt research suggests that dermatologists can make patients more comfortable during full-body skin cancer screenings by respecting patient preferences for the physician's gender as well as whether, and how, they prefer to have their genitals examined.
National Institutes of Health

Contact: Amy Charley
CharleyA@upmc.edu
412-586-9778
University of Pittsburgh Schools of the Health Sciences

Public Release: 11-May-2016
Lancet Oncology
Quality of life meets cure for prostate cancer treatment
A new paper looks at how MRI and a clear understanding of the functional anatomy around the prostate can allow radiation oncologists to plan a course of treatment for patients with prostate cancer that spares these critical structures.

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 11-May-2016
American Geriatrics Society (AGS) 2016 Annual Scientific Meeting
New PSA test examines protein structures to detect prostate cancers
A promising new test is detecting prostate cancer more precisely than current tests, by identifying molecular changes in the prostate specific antigen (PSA) protein, according to Cleveland Clinic research presented at the American Urological Association annual meeting.

Contact: Maureen Nagg
naggm@ccf.org
216-636-5879
Cleveland Clinic

Public Release: 11-May-2016
Small
New device developed at UBC could improve cancer detection
A new UBC-developed method to isolate cancer cells that have escaped from a tumor could soon pave the way for improved diagnosis and treatment.

Contact: Lou Bosshart
lou.bosshart@ubc.ca
604-999-0473
University of British Columbia

Public Release: 11-May-2016
Journal of Thoracic Oncology
Validation of an IHC screening tool for ROS1 gene rearrangements
Immunohistochemistry (IHC) is an effective tool that can be used for identifying proto-oncogene 1 receptor tyrosine kinase (ROS1) gene rearrangements and screening patients for the administration of the targeted therapy crizotinib, a small-molecule tyrosine kinase inhibitor.

Contact: Jeff Wolf
Jeff.Wolf@iaslc.org
720-325-2952
International Association for the Study of Lung Cancer

Public Release: 11-May-2016
Biosensors and Bioelectronics
No symptoms, but could there be cancer? Our chemosensor will detect it!
Many cancers could be successfully treated if the patient consulted the doctor sufficiently early. But how can a developing cancer be detected if it doesn't give rise to any symptoms? In the near future, suitably early diagnosis could be provided by simple and cheap chemical sensors -- thanks to special recognizing polymer films developed at the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw.

Contact: Wlodzimierz Kutner
wkutner@ichf.edu.pl
48-223-433-217
Institute of Physical Chemistry of the Polish Academy of Sciences

Showing releases 126-150 out of 1352.

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