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Showing releases 1251-1275 out of 1332.

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Public Release: 4-Nov-2014
Immune booster combined with checkpoint blocker improves survival in metastatic melanoma
Patients with metastatic melanoma who were treated with ipilimumab, an immune checkpoint blocker, survived 50 percent longer if they simultaneously received an immune stimulant.
US Public Health Service, NIH/National Cancer Institute, National Institutes of Health, US Department of Health and Human Services

Contact: Teresa Herbert
Dana-Farber Cancer Institute

Public Release: 4-Nov-2014
Journal of the National Cancer Institute Monographs
Studies show exercise therapy, acupuncture benefit breast cancer survivors
Two new studies from the Abramson Cancer Center and the Perelman School of Medicine at the University of Pennsylvania offer hope for breast cancer survivors struggling with cancer-related pain and swelling, and point to ways to enhance muscular strength and body image. The studies appear in a first of its kind monograph from the Journal of the National Cancer Institute Monographs focusing on integrative oncology, which combines a variety of therapies, some non-traditional, for maximum benefit to cancer patients.

Contact: Katie Delach
University of Pennsylvania School of Medicine

Public Release: 4-Nov-2014
Combination treatment for metastatic melanoma results in longer overall survival
Among patients with metastatic melanoma, treatment with a combination of the drugs sargramostim plus ipilimumab, compared with ipilimumab alone, resulted in longer overall survival and lower toxicity, but no difference in progression-free survival, according to a study in the Nov. 5 issue of JAMA.

Contact: Teresa Herbert
The JAMA Network Journals

Public Release: 4-Nov-2014
Society for Integrative Oncology's 11th International Conference
Journal of the National Cancer Institute
Report card on complementary therapies for breast cancer
Over 80 percent of breast cancer patients in the United States use complementary therapies following a breast cancer diagnosis, but there has been little science-based guidance to inform clinicians and patients about their safety and effectiveness. In newly published guidelines, researchers analyzed which integrative treatments appear to be most effective and safe for patients. They evaluated more than 80 different therapies.
Society for Integrative Oncology

Contact: Stephanie Berger
Columbia University's Mailman School of Public Health

Public Release: 4-Nov-2014
Proceedings of the National Academy of Sciences
How important is long-distance travel in the spread of epidemics?
When modeling the spread of epidemics, such as the Ebola outbreak, scientists must take into account the long-distance hops now possible with international air travel. But how important are such long-distance jumps? A new model by biophysicists Oskar Hallatschek of UC Berkeley and Daniel Fisher of Stanford shows that how common long-range jumps are makes a big difference in the dispersal of a disease, that is, whether you get slow, rippling versus rapid metastatic spread.
Simons Foundation, National Science Foundation

Contact: Robert Sanders
University of California - Berkeley

Public Release: 4-Nov-2014
British Journal of Cancer
Lactose intolerants at lower risk of certain cancers: Study
People with lactose intolerance are at lower risk of suffering from lung, breast and ovarian cancers, according to a new study by researchers at Lund University and Region Skåne in Sweden.

Contact: Jianguang Ji
Lund University

Public Release: 4-Nov-2014
National Cancer Research Institute (NCRI) Cancer Conference
Patients with emergency-diagnosed lung cancer report barriers to seeing their GP
Many patients whose lung cancer is diagnosed as an emergency in hospital reported difficulties in previously seeing their general practitioner.

Contact: Simon Shears
Cancer Research UK

Public Release: 4-Nov-2014
National Cancer Research Institute (NCRI) Cancer Conference
Hot flushes are going unrecognized, leaving women vulnerable
Hot flushes are one of the most distressing conditions faced by women who have been treated for breast cancer, but they are not being adequately addressed by health-care professionals and some women consider giving up their post cancer medication to try and stop them, a new study has shown.

Contact: Becky Attwood
University of Southampton

Public Release: 4-Nov-2014
National Cancer Research Institute (NCRI) Cancer Conference
Gene 'switches' could predict when breast cancers will spread to the brain
Scientists have found a pattern of genetic 'switches' -- chemical marks that turn genes on or off -- that are linked to breast cancer's spread to the brain.

Contact: Simon Shears
Cancer Research UK

Public Release: 4-Nov-2014
National Cancer Research Institute (NCRI) Cancer Conference
Scientists uncover potential drug to tackle 'undruggable' fault in third of cancers
Scientists have found a possible way to halt one of the most common faults in many types of cancer.

Contact: Stephanie McClellan
Cancer Research UK

Public Release: 4-Nov-2014
Researchers engineer a 'smart bomb' to attack childhood leukemia
Fatih Uckun, Jianjun Cheng and their colleagues have taken the first steps towards developing a so-called 'smart bomb' to attack the most common and deadly form of childhood cancer -- called B-lineage acute lymphoblastic leukemia.
University of Southern California Stem Cell's Regenerative Medicine Initiative, National Cancer Institute, National Institutes of Health,

Contact: Cristy Lytal
University of Southern California - Health Sciences

Public Release: 4-Nov-2014
National Cancer Research Institute (NCRI) Cancer Conference
Trial results reveal first targeted treatment to boost survival for esophageal cancer
Patients with a specific type of esophageal cancer survived longer when they were given the latest lung cancer drug, according to trial results being presented at the National Cancer Research Institute Cancer Conference on Nov. 5.
Scottish Government's Chief Scientist Office, Cameron Clinical Academic Fellowship, Grampian Gastro-oesophageal Cancer Research Fund

Contact: Ailsa Stevens
Cancer Research UK

Public Release: 3-Nov-2014
Lung cancer diagnosed before it is detected by imaging
A team of researchers from Inserm led by Paul Hofman shows in the journal PLOS ONE, that it is possible to detect, in patients at risk of developing lung cancer, early signs, in the form of circulating cancer cells, several months, and in some cases several years, before the cancer becomes detectable by CT scanning. This warning could play a key role in early surgical intervention, thereby making it possible to attempt the early eradication of the primary cancer site.

Contact: Paul Hofman
INSERM (Institut national de la santé et de la recherche médicale)

Public Release: 3-Nov-2014
Lancet Haematology
New classification improves risk prediction in chronic lymphocytic leukemia
If chronic lymphocytic leukemia patients with a good or poor prognosis could be identified already at the time of diagnosis, physicians would have better possibilities to adjust their therapeutic and follow-up strategies. Now researchers at Uppsala University, together with international colleagues, have discovered a new correlation between specific molecular features of the disease and subgroups of patients with different prognosis.

Contact: Richard Rosenquist Brandell
Uppsala University

Public Release: 3-Nov-2014
Journal of Experimental Medicine
Immunotherapy for cancer toxic with obesity
Immunotherapy that can be effective against tumors in young, thin mice can be lethal to obese ones, a new study by UC Davis researchers has found.
NIH/National Institute of Aging

Contact: Dorsey Griffith
University of California - Davis Health System

Public Release: 3-Nov-2014
Study shows clear new evidence for mind-body connection
For the first time, researchers have shown that practicing mindfulness meditation or being involved in a support group has a positive physical impact at the cellular level in breast cancer survivors.
Alberta Cancer Foundation, Canadian Breast Cancer Research Alliance

Contact: Gregory Harris
Alberta Health Services

Public Release: 3-Nov-2014
National Cancer Research Institute (NCRI) Cancer Conference
Swallowing a sponge on a string could replace endoscopy as pre-cancer test
Swallowing a sponge on a string could replace traditional endoscopy as an equally effective but less invasive way of diagnosing a condition that can be a forerunner of esophageal cancer.
Cancer Research UK

Contact: Greg Jones
Cancer Research UK

Public Release: 3-Nov-2014
Journal of Experimental Medicine
Obesity a liability in cancer immunotherapy
Packing on the pounds may lead to dangerous inflammation in response to anti-cancer treatment. A University of California Davis study shows that overweight mice develop lethal inflammation in response to certain anti-cancer therapies, suggesting a possible link between body weight and adverse side effects.
National Institutes of Health, NIH/National Institute on Aging

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 3-Nov-2014
Academic Medicine
Preclinical oncology coursework could help with practitioner shortage
The research showed an increase in the number of students considering specializing in oncology -- from 22 percent pre-course to 39 percent post-course. These issues are especially pertinent across the globe today, including in Israel and North America. In Israel, the ratio of newly diagnosed patients to oncologists was 24,992 cancer patients to 180 oncologists in 2010.

Contact: Andrew Lavin
American Associates, Ben-Gurion University of the Negev

Public Release: 3-Nov-2014
Plastic and Reconstructive Surgery
Comprehensive breast center improves quality of care for breast reconstruction
After opening a comprehensive breast center, one hospital achieved significant improvement in key measures of quality of care for women undergoing breast reconstruction, reports the November issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

Contact: Connie Hughes
Wolters Kluwer Health

Public Release: 3-Nov-2014
Journal of Clinical Oncology
Telephone counseling leads more adult childhood cancer survivors to get heart screenings
Supplementing written heart screening guidelines with telephone counseling from specially trained nurses more than doubled the likelihood that adult survivors of childhood cancer received recommended heart checks, according to results from the Childhood Cancer Survivor Study. St. Jude Children's Research Hospital investigators led the research, whose findings appear in the current issue of the Journal of Clinical Oncology.
National Institutes of Health, ALSAC

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Public Release: 3-Nov-2014
Proceedings of the National Academy of Sciences
NSAIDs prevent colon cancer by inducing death of intestinal stem cells that have mutation
Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) protect against the development of colorectal cancer by inducing cell suicide pathways in intestinal stem cells that carry a certain mutated and dysfunctional gene, according to a new study led by researchers at the University of Pittsburgh Cancer Institute and the School of Medicine. The findings were published online today in the Proceedings of the National Academy of Sciences.
National Institutes of Health, American Cancer Society

Contact: Allison Hydzik
University of Pittsburgh Schools of the Health Sciences

Public Release: 3-Nov-2014
Journal of Health Communication
Massey researchers develop the first cancer health literacy tool
Virginia Commonwealth University Massey Cancer Center researchers have developed the first and only tool that can accurately measure cancer health literacy and quickly identify patients with limited CHL. This tool has the potential to improve communication and understanding between physicians and patients, which, in turn, could lead to better clinical outcomes.
National Cancer Institute

Contact: John J Wallace
Virginia Commonwealth University

Public Release: 3-Nov-2014
Proceedings of the National Academy of Sciences
PNAS: From HIV to cancer, IL-37 regulates immune system
A University of Colorado Cancer Center study published in this month's Proceedings of the National Academy of Sciences describes the activity of a recently discovered communication molecule of the body's immune system, Interleukin 37 or IL-37. It has been known to limit inflammation and the current study reports its activity in the adaptive immune system: IL-37 inhibits the ability of the immune system to recognize and target new antigens.
National Institutes of Health

Contact: Garth Sundem
University of Colorado Denver

Public Release: 2-Nov-2014
National Cancer Research Institute (NCRI) Cancer Conference
Sea sponge drug could boost advanced breast cancer survival by 5 extra months
The cancer drug eribulin, originally developed from sea sponges, could give women with advanced triple negative breast cancer an average of five extra months of life, according to research presented at the National Cancer Research Institute Cancer Conference in Liverpool Monday.

Contact: Greg Jones
Cancer Research UK

Showing releases 1251-1275 out of 1332.

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