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Showing releases 1301-1325 out of 1345.

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Public Release: 5-Dec-2015
57th ASH Annual Meeting & Exposition
Making cancer care personal
Researchers at the University of Iowa College of Dentistry are partnering with a private company to develop computer simulations that can help personalize cancer care by predicting how a patient will respond to a drug treatment.

Contact: Sara Diedrich
sara-diedrich@uiowa.edu
319-384-0073
University of Iowa

Public Release: 4-Dec-2015
BMC Genomics
Scientists investigated molecular processes for targeted dog cancer therapy
Dogs get cancer, just like humans. Scientists at the Vetmeduni Vienna are now exploring the molecular basis of cancer progression in canine cell lines. A research team led by Sabine Macho-Maschler has investigated the activation of genetic regulatory mechanisms in canine cells and found both matches as well as differences compared to man. Thy study was published in the journal BMC Genomics.

Contact: Susanna Berger
susanna.berger@vetmeduni.ac.at
43-125-077-1153
University of Veterinary Medicine -- Vienna

Public Release: 4-Dec-2015
Nature Communications
'Purity' of tumor samples may significantly bias genomic analyses
A new study by UC San Francisco scientists shows that the proportion of normal cells, especially immune cells, intermixed with cancerous cells in a given tissue sample may significantly skew the results of genetic analyses and other tests performed both by researchers and by physicians selecting precision therapies.

Contact: Pete Farley
peter.farley@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 4-Dec-2015
Lancet Oncology
Breast screening program effective in preventing some invasive cancers
Screening for and treatment of an early form of breast cancer has been found to prevent subsequent invasive cancer, according to research led by Queen Mary University of London.
UK Department of Health Policy Research Programme, NHS Cancer Screening Programmes

Contact: Joel Winston
j.winston@qmul.ac.uk
44-207-882-7943
Queen Mary University of London

Public Release: 4-Dec-2015
American Society of Hematology Annual Meeting
New leads in the struggle against a formidable leukemia
Beat AML initiative, led by the Knight Cancer Institute at Oregon Health & Science University and The Leukemia & Lymphoma Society, presents new research findings at the American Society of Hematology Annual Meeting.

Contact: Amanda Gibbs
gibbam@ohsu.edu
Oregon Health & Science University

Public Release: 4-Dec-2015
Cancer Cell
Signaling pathway suppresses brain tumors
Researchers at the University of Basel took a close look at a signaling pathway present in most organisms and found that it suppresses the formation of specific types of brain tumor. Their results have been published by the journal Cancer Cell.

Contact: Yannik Sprecher
yannik.sprecher@unibas.ch
41-612-672-424
University of Basel

Public Release: 4-Dec-2015
American Society of Hematology
Montefiore-Einstein Investigators present research at 2015 American Society of Hematology Annual Meeting
Investigators at Montefiore Einstein Center for Cancer Care, Albert Einstein College of Medicine's NCI-designated Albert Einstein Cancer Center and The Children's Hospital at Montefiore will present findings at the American Society of Hematology's 57th Annual Meeting. Presentations will include a report on a genetic risk factor for avascular necrosis associated with treatment of acute lymphoblastic leukemia in children, insights into the molecular basis for acute myeloid leukemia and a novel approach to its treatment.

Contact: Tracy Gurrisi
TGurrisi@montefiore.org
718-920-8274
Albert Einstein College of Medicine

Public Release: 4-Dec-2015
Journal of Clinical Investigation
Guided ultrasound plus nanoparticle chemotherapy cures tumors in mice
Thermal ablation with magnetic resonance-guided focused ultrasound surgery (MRgFUS) is a noninvasive technique for treating fibroids and cancer. New research from UC Davis shows that combining the technique with chemotherapy can allow complete destruction of tumors in mice.
National Institutes of Health

Contact: Andy Fell
ahfell@ucdavis.edu
530-752-4533
University of California - Davis

Public Release: 4-Dec-2015
Cell Reports
Gene pair plays crucial role in colon cancer, Penn vet team shows
In a new study out this month in the journal Cell Reports, researchers from the University of Pennsylvania describe two related genes in the Musashi family that are required for colon cancer to develop, and that may be useful targets for effective treatment.
NIH/National Institute for Diabetes and Digestive and Kidney Disorders

Contact: Katherine Unger Baillie
kbaillie@upenn.edu
215-898-9194
University of Pennsylvania

Public Release: 4-Dec-2015
Developmental Cell
Microtubules act as cellular 'rheostat' to control insulin secretion
Microtubules -- cellular 'highways' that deliver cargo to the cell membrane for secretion -- have a surprising role in pancreatic beta cells. Instead of facilitating glucose-stimulated insulin secretion, they limit it, a team of Vanderbilt investigators reported recently in Developmental Cell. The findings reveal that microtubules act as a cellular 'rheostat' to precisely control insulin secretion and suggest that disturbance of this control may contribute to beta cell dysfunction and type 2 diabetes.
National Institutes of Health, American Heart Association, US Department of Veterans Affairs, Juvenile Diabetes Research Foundation

Contact: Leigh MacMillan
leigh.macmillan@vanderbilt.edu
615-322-4747
Vanderbilt University Medical Center

Public Release: 3-Dec-2015
Nature Communications
How to wake a sleeping cancer cell -- and why you might want to
Cancer cells that lie 'snoozing' in the skeleton can be awakened by changes in the bone that surrounds them, Australian scientists have shown. In a world first, researchers from the Garvan Institute of Medical Research have used state-of-the-art microscopy techniques to watch cancer cells sleep within living bone over a period of months. They show that cancer cells can be 'woken up' when bone tissue is broken down around them, suggesting new possibilities for treating metastatic cancer in bone.
Mrs. Janice Gibson, Ernest Heine Family Foundation, National Health and Medical Research Council (Australia), International Bone and Mineral Society, Australian Research Council, Leukaemia and Lymphoma Research

Contact: Meredith Ross
m.ross@garvan.org.au
043-987-3258
Garvan Institute of Medical Research

Public Release: 3-Dec-2015
Cell
'Master switch' helps cancer cells survive stress
Scientists have discovered a 'master switch' within cancer cells that seems to override the normal stress response and allows them to survive conditions that would normally be lethal. The mechanism could be critical in allowing cancer cells to withstand the huge amounts of stress they come under as they divide rapidly and their metabolism goes into overdrive.
The Institute of Cancer Research, Biotechnology and Biological Sciences Research Council

Contact: Claire Hastings
chastings@icr.ac.uk
020-715-35380
Institute of Cancer Research

Public Release: 3-Dec-2015
Cell Reports
Spreading cancer cells must change their environment to grow
Spreading cancer cells arriving in a new part of the body must be able to change their new environment to continue to grow.

Contact: Press Office
press.office@cancer.org.uk
020-346-98300
Cancer Research UK

Public Release: 3-Dec-2015
Scientific Reports
Researchers isolate cells implicated with breast cancer-derived brain tumors
Researchers from the Houston Methodist Research Institute have isolated genetic signatures of some circulating tumor cells found in breast cancer, which one day may lead to a preventive treatment for metastatic cancer cells.

Contact: Gale Smith
gsmith@houstonmethodist.org
281-627-0439
Houston Methodist

Public Release: 3-Dec-2015
JAMA Oncology
Neurotoxic effects of chemotherapies on cognition in breast cancer survivors
Cancer-related cognitive impairment is often referred to as 'chemobrain' and anthracycline-based chemotherapy may have greater negative effects on particular cognitive domains and brain network connections than nonanthracycline-based regimens, according to an article published online by JAMA Oncology.

Contact: Laura Sussman
lsussman@mdanderson.org
713-745-2457
The JAMA Network Journals

Public Release: 3-Dec-2015
Annals of Oncology
Study shows abiraterone acetate is useful even in most aggressive prostate cancers
In study of nearly 2,000 prostate cancer patients, treatment with the androgen-lowering drug abiraterone acetate (Zytiga) led to longer overall disease control, even when a very high Gleason score indicated especially aggressive cancer.

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Anschutz Medical Campus

Public Release: 3-Dec-2015
Scientific Reports
Researchers use ovarian follicles to preserve fertility
Researchers at the University of Michigan have identified a potential new approach to fertility preservation for young cancer patients that addresses concerns about beginning cancer treatment immediately and the possibility of reintroducing cancer cells during the fertility preservation process.
National Institutes of Health

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 3-Dec-2015
American Journal of Respiratory and Critical Care Medicine
Researchers identify biomarker of early lung cancer that may increase survival
Researchers in Taiwan have identified a biomarker that detects the most common lung cancer in its earliest stage. The discovery could one day change how long lung cancer patients live.
The National Research Program for Biopharmaceuticals of Taiwan, National Research Institutes of Taiwan

Contact: Rory Williams
rwilliams@thoracic.org
212-315-8631
American Thoracic Society

Public Release: 3-Dec-2015
Pyschosomatic Medicine
Depressed head and neck cancer patients three-and-one-half times less likely to survive, have higher recurrence risk
Depression is a significant predictor of five-year survival and recurrence in head and neck cancer patients, according to a new study from The University of Texas MD Anderson Cancer Center.

Contact: Clayton R. Boldt, Ph.D.
crboldt@mdanderson.org
713-792-9518
University of Texas M. D. Anderson Cancer Center

Public Release: 3-Dec-2015
Advanced Materials
'Nanobombs' might deliver agents that alter gene activity in cancer stem cells
Researchers at The Ohio State University Comprehensive Cancer Center -- Arthur G. James Cancer Hospital and Richard J. Solove Research Institute have developed nanoparticles that swell and burst when exposed to near-infrared laser light. Such 'nanobombs' might overcome a biological barrier that has blocked development of agents that work by altering the activity -- the expression -- of genes in cancer cells. The agents might kill cancer cells outright or stall their growth.
American Cancer Society, Pelotonia Postdoctoral Fellowship

Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Wexner Medical Center

Public Release: 3-Dec-2015
57th ASH Annual Meeting & Exposition
Cancer Cell
Targeting protein homeostasis holds potential to treat solid tumors and blood cancers
In data published in two journals as well as to be presented at the American Society of Hematology Annual Meeting & Exposition, scientists identified an orally available molecule, CB-5083, that targeting protein homeostasis has the potential to treat solid tumors and blood cancers.
Cleave Biosciences

Contact: Pam Lord
pam@canalecomm.com
619-849-6003
Canale Communications

Public Release: 2-Dec-2015
Structure
New studies create better understanding of cancer-spreading enzymes
Researchers at the University of Missouri have determined a detailed structural view of one of these enzymes, called MMP7, as it binds to the membranes, or surfaces, of cancer cells. This understanding could lead to better treatments for cancer.
National Institutes of Health, Burroughs Wellcome Fund Career Award at the Scientific Interface

Contact: Nathan Hurst
hurstn@missouri.edu
573-882-6217
University of Missouri-Columbia

Public Release: 2-Dec-2015
57th ASH Annual Meeting & Exposition
City of Hope researchers present study results at American Society of Hematology meeting
Clinical trials that lay the groundwork for novel leukemia and lymphoma treatments will be among the highlights of the annual meeting of the American Society of Hematology (ASH) getting under way this week in Orlando. The trials, presented by researchers and physicians from City of Hope, could ultimately lead to innovative therapeutic approaches that improve survival and quality of life for patients with those and other diseases.

Contact: Letisia Marquez
media@coh.org
800-888-5323
City of Hope

Public Release: 2-Dec-2015
Crop Science
Fries with a side of acrylamide
French fry lovers, beware! You may be exposed to a chemical more commonly associated with heavy industry than crispy fried potatoes. Fortunately, researchers are finding ways to reduce that exposure.
US Potato Board, Cavendish Foods, ConAgra Lamb-Weston, J.R. Simplot, McCain Foods, National Institute of Food and Agriculture USDA Specialty Crop Research Initiative

Contact: Susan Fisk
sfisk@sciencesocieties.org
608-273-8091
American Society of Agronomy

Public Release: 2-Dec-2015
57th ASH Annual Meeting & Exposition
Sylvester presents latest cancer research at ASH Annual Meeting
Researchers from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine will present a selection of the latest advances in hematology research at this year's American Society of Hematology Annual Meeting, Dec. 5-8, at the Orange County Convention Center in Orlando, Fla.

Contact: Patrick Bartosch
patrick.bartosch@med.miami.edu
201-469-6408
University of Miami Miller School of Medicine

Showing releases 1301-1325 out of 1345.

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