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Showing releases 1301-1316 out of 1316.

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Public Release: 2-Mar-2015
Journal of Cell Biology
Sall4 is required for DNA repair in stem cells
A protein that helps embryonic stem cells retain their identity also promotes DNA repair. The findings raise the possibility that the protein, Sall4, performs a similar role in cancer cells, helping them survive chemotherapy.
Chinese Ministry of Science and Technology, California Institute for Regenerative Medicine

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 2-Mar-2015
Nature Genetics
Healthy-looking prostate cells mask cancer-causing mutations
Prostate cells that look normal under the microscope may be hiding genetic mutations that could develop into cancer, prompting new ways to improve treatment for the disease, according to research published in Nature Genetics.
Cancer Research UK, Wellcome Trust

Contact: Greg Jones
Cancer Research UK

Public Release: 2-Mar-2015
Journal of Clinical Oncology
US women's awareness of breast density varies
Disparities in the level of awareness and knowledge of breast density exist among US women, according to the results of a Mayo Clinic study published in the Journal of Clinical Oncology.

Contact: Joe Dangor
Mayo Clinic

Public Release: 2-Mar-2015
Journal of Experimental Medicine
Promising new strategy to halt pancreatic cancer metastasis
Researchers have identified a novel treatment that could halt the spread of pancreatic cancer and prolong patient survival.
Academia Sinica, Ministry of Science and Technology Taiwan

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 2-Mar-2015
SIR 2015 Annual Scientific Meeting
3-D printing offers innovative method to deliver medication
3-D printing could become a powerful tool in customizing interventional radiology treatments to individual patient needs, with clinicians having the ability to construct devices to a specific size and shape. Researchers and engineers collaborated to print catheters, stents and filaments to deliver antibiotics and chemotherapeutic medications to a targeted area in cell cultures.

Contact: Ellen Acconcia
Society of Interventional Radiology

Public Release: 2-Mar-2015
International Journal of Radiation Oncology • Biology • Physics
Improved survival for patients with brain mets who are 50 and younger and receive SRS alone
Cancer patients with limited brain metastases -- one to four tumors -- who are 50 years old and younger should receive stereotactic radiosurgery (SRS) without whole brain radiation therapy, according to a study available online, open-access, and published in the March 15, 2015 issue of the International Journal of Radiation Oncology * Biology * Physics.

Contact: Michelle Kirkwood
American Society for Radiation Oncology

Public Release: 2-Mar-2015
American Journal of Clinical Oncology
Use of new systemic adjuvant therapy in gastrointestinal tumors increasing
A new study finds that the use of adjuvant systemic therapy for localized gastrointestinal stromal tumors has significantly increased over time and that patients treated with the therapy have better survival than those treated with surgery alone.
American Cancer Society

Contact: David Sampson
American Cancer Society

Public Release: 2-Mar-2015
Nature Cell Biology
Researchers discover 'milk' protein that enables survival of the species
Australian researchers have discovered the protein MCL-1 is critical for keeping milk-producing cells alive and sustaining milk production in the breast. Without milk production, offspring cannot survive, making MCL-1 essential for survival of mammalian species.
National Health and Medical Research Council, Australian Cancer Research Foundation, National Breast Cancer Foundation, Cure Cancer Australia Foundation, Victorian Government

Contact: Liz Williams
Walter and Eliza Hall Institute

Public Release: 2-Mar-2015
Lycopene may ward off kidney cancer in older women
A higher intake by postmenopausal women of the natural antioxidant lycopene, found in foods like tomatoes, watermelon and papaya, may lower the risk of renal cell carcinoma, a type of kidney cancer.
NIH/National Heart, Lung and Blood Institute

Contact: Julie O'Connor
Wayne State University - Office of the Vice President for Research

Public Release: 2-Mar-2015
Respiratory Research
Researchers identify genes responsible for lung tumors
The lung transcription factor Nkx2-1 is an important gene regulating lung formation and normal respiratory functions after birth. Alterations in the expression of this transcription factor can lead to diseases such as lung interstitial disease, post-natal respiratory distress and lung cancer.
National Institutes of Health

Contact: Gina DiGravio
Boston University Medical Center

Public Release: 2-Mar-2015
Restoring ability to halt cell division may protect lung cells from cancer
Researchers led by a team at the University of Illinois at Chicago, have identified a novel role for a signaling mechanism in lung cells that permanently places them into a state of suspended animation called senescence. Alive but unable to do much of anything, including divide, senescent cells cannot become cancerous. Drugs that can induce senescence through this signaling pathway would represent a new class of chemotherapy.
US Department of Veterans Affairs, National Institutes Health

Contact: Sharon Parmet
University of Illinois at Chicago

Public Release: 2-Mar-2015
Human Molecular Genetics
New data on the regulation of the genetic activity that protects against lung cancer
Scientists at the University of Granada, in collaboration with the universities of Harvard and Yale have provided new data for a better understanding of the alterations produced during the development of lung cancer, the tumor with the highest yearly death rate in Spain.

Contact: Pedro Medina Vico
University of Granada

Public Release: 2-Mar-2015
Inorganic Chemistry
Preventing the spread of cancer with copper molecules
Chemists at Bielefeld University have developed a molecule containing copper that binds specifically with DNA and prevents the spread of cancer. First results show that it kills the cancer cells more quickly than cisplatin -- a widely used anti-cancer drug that is frequently administered in chemotherapy. When developing the anti-tumor agent, Dr. Thorsten Glaser and his team cooperated with biochemists and physicists. The design of the new agent is basic research.

Contact: Dr. Thorsten Glaser
Bielefeld University

Public Release: 2-Mar-2015
FASEB Journal
Researchers identify the mitochondrial 'shield' that helps cancer cells survive
Scientists have moved closer to understanding why cancer cells can be so resilient, even when faced with the onslaught of nearly toxic drug cocktails, radiation, and even our own immune systems. A new research report appearing in the March 2015 issue of The FASEB Journal shows that intermediate filaments formed by a protein called 'vimentin' or VIF, effectively 'insulate' the mitochondria in cancer cells from any attempt to destroy the cell.

Contact: Cody Mooneyhan
Federation of American Societies for Experimental Biology

Public Release: 2-Mar-2015
Proceedings of the National Academy of Sciences
New nanodevice defeats drug resistance
A nanodevice from MIT researchers can disable drug-resistance genes, then release cancer drugs.
NIH/National Cancer Institute, Marie Curie International Outgoing Fellowship

Contact: Sarah McDonnell
Massachusetts Institute of Technology

Public Release: 1-Mar-2015
British Journal of General Practice
Black men less willing to be investigated for prostate cancer
To investigate the possible effects of patients' preferences and choices, a team led by the University of Exeter Medical School carried out a study in more than 500 men attending general practices.

Contact: Louise Vennells
University of Exeter

Showing releases 1301-1316 out of 1316.

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