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Showing releases 151-175 out of 1210. << < 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 > >>
Public Release: 1-May-2013
 New England Journal of MedicineScientists assemble genetic playbook for acute leukemia team of researchers led by Washington University School of Medicine in St. Louis has identified virtually all of the major mutations that drive acute myeloid leukemia, a fast-growing blood cancer in adults that often is difficult to treat. 
National Institutes of Health, Barnes-Jewish Hospital Foundation
Contact: Caroline Arbanas
Public Release: 1-May-2013
NatureGenomics to reshape endometrial cancer treatment The most in-depth look yet at endometrial cancer shows that adding genomics-based testing to the standard diagnostic workup could change the recommended course of treatment for some women.
National Institutes of Health
Contact: Caroline Arbanas
Public Release: 1-May-2013
NatureA paradigm shift in endometrial cancer Results from the Cancer Genome Atlas Research Network may change the way endometrial cancers are classified and provide opportunities to test new treatment protocols for patients with this cancer.
National Institutes of Health
Contact: Marjorie Montemayor-Quellenberg
Public Release: 1-May-2013
Nature MedicineStudy finds key protein for firing up central nervous system inflammation Scientists have identified an influential link in a chain of events that leads to autoimmune inflammation of the central nervous system in a mouse model of multiple sclerosis. Contact: Scott Merville
Public Release: 1-May-2013
Journal of Clinical InvestigationJCI early table of contents for May 1, 2013 The following release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, May 1, 2013, in the JCI. Contact: Jillian Hurst
Public Release: 1-May-2013
Journal of Clinical InvestigationHPV leaves its mark in oropharyngeal squamous cell carcinoma In this issue of the Journal of Clinical Investigation, Jochen Hess and colleagues identified a specific pattern of DNA modification that is dependent on the presence of HPV.
Dietmar Hopp Stiftung, Stiftung Tumorforschung Kopf-Hals, German Research Foundation
Contact: Jillian Hurst
Public Release: 1-May-2013
New England Journal of MedicineComputer algorithms help find cancer connections Using powerful algorithms developed by computer scientists at Brown University, medical researchers have assembled the most complete genetic profile yet of acute myeloid leukemia, an aggressive form of blood cancer. Findings are reported in the New England Journal of Medicine.
National Institutes of Health
Contact: Kevin Stacey
Public Release: 1-May-2013
Journal of Clinical InvestigationSearching for therapeutic synergy in primary effusion lymphoma In this issue of the Journal of Clinical Investigation, Juan Carlos Ramos and colleagues at the University of Miami used an immunocompromised mouse model of PEL to determine the efficacy of Bortezomib/Vorinostat combination therapy.
NIH/Developmental Center for AIDS Research, Dwoskin Family, Recio Foundations
Contact: Jillian Hurst
Public Release: 1-May-2013
NatureLarge genomic study identifies endometrial cancer subtypes, treatment opportunities An analysis of endometrial cancers reveals genetic information that should improve diagnosis and guide treatments for women with an aggressive form of the disease.
NIH/National Cancer Institute
Contact: Caitlin Hool
Public Release: 1-May-2013
Biology of Blood and Marrow TransplantationResearchers look to mathematics, nature, to understand the immune system and its role in cancer Can patterns in tree branches or the meandering bends in a river provide clues that could lead to better cancer therapies? According to a new study from Virginia Commonwealth University Massey Cancer Center, these self-similar, repeating patterns in nature known as fractals help scientists better understand how the immune system is organized and may one day be used to help improve stem cell transplant outcomes in leukemia patients by predicting the probability of transplant complications.
NIH/National Cancer Institute
Contact: John Wallace
Public Release: 1-May-2013
Sexually Transmitted DiseasesSelf-collection of samples for HPV testing shows promise in detection of cervical cancer in Kenya A study by researchers at the University of North Carolina at Chapel Hill suggests that training women to self-collect genital samples to test for human papillomavirus, the causative agent of cervical cancer, can increase the coverage rates of cervical cancer screening. Contact: William Davis
Public Release: 1-May-2013
NatureEndometrial and acute myeloid leukemia cancer genomes characterized Two studies from the Cancer Genome Atlas program reveal details about the genomic landscapes of acute myeloid leukemia and endometrial cancer. Both provide new insights into the molecular underpinnings of these cancers with the potential to improve treatment. These studies represent the sixth and seventh in a series of genomes of at least 20 major cancers.
National Institutes of Health
Contact: NCI Press Office
Public Release: 1-May-2013
Proceedings of the National Academy of Sciences'Traffic' in our cells works both for and against us A mechanism that permits essential substances to enter our cells while at the same time removing from them harmful components also has a "down side." This negative aspect prevents vital drugs, such as anti-cancer drugs, from achieving their designed functions, while also enabling bacterial cells to develop resistance to penetration of antibiotics. Contact: Jerry Barach
Public Release: 1-May-2013
AUA Annual Meeting 2013Ferring to present safety analysis for FIRMAGONŽ (degarelix) at the AUA Annual Meeting A safety analysis for FIRMAGONŽ (degarelix) will be presented at the annual meeting of the American Urology Association in San Diego, CA.
Ferring Pharmaceuticals
Contact: Molly Wilson
Public Release: 1-May-2013
NatureScripps Research Institute scientists find dissimilar proteins evolved similar 7-part shape Solving the structure of a critical human molecule involved in cancer, scientists at The Scripps Research Institute have found what they call a good example of structural conservation -- dissimilar genes that keep very similar shapes.
National Institutes of Health
Contact: Mika Ono
Public Release: 30-Apr-2013
Clinical Cancer ResearchMayo Clinic finds experimental drug inhibits growth in all stages of common kidney cancer Researchers at Mayo Clinic's campus in Florida have discovered a protein that is overly active in every human sample of kidney cancer they examined. They also found that an experimental drug designed to block the protein's activity significantly reduced tumor growth in animals when used alone. Combining it with another drug already used to treat the cancer improved the effectiveness of both.
NIH/National Cancer Institute
Contact: Kevin Punsky
Public Release: 30-Apr-2013
mBioProtein improves efficacy of tumor-killing enzyme Scientists have devised a method for delivering tumor cell-killing enzymes in a way that protects the enzyme until it can do its work inside the cell. In their study in mBioŽ, the online open-access journal of the American Society for Microbiology, researchers assembled microscopic protein packages that can deliver an enzyme called PEIII to the insides of cells. Contact: Jim Sliwa
Public Release: 30-Apr-2013
PLOS MedicineUpper GI bleed linked to death from other causes Individuals who have experienced a major bleed from their stomach or oesophagus (known as an upper gastrointestinal bleed) may be more likely to die from other causes, particularly malignant tumours and cardiovascular disease, than those without an upper gastrointestinal bleed, according to a study by UK researchers published in this week's PLOS Medicine.
Medical Research Council Population Health Scientist, University of Nottingham
Contact: Fiona Godwin
Public Release: 30-Apr-2013
SleepSleep duration associated with higher colorectal cancer risk A new study is the first to report a significant positive association between long sleep duration and the development of colorectal cancer, especially among individuals who are overweight or snore regularly. The results raise the possibility that obstructive sleep apnea may contribute to cancer risk.
National Institutes of Health
Contact: Lynn Celmer
Public Release: 30-Apr-2013
JAMA Media Briefing on Child Health JAMAStudy compares effectiveness of 2 vs. 3 doses of HPV vaccine for girls and young women With the number of doses and cost of human papillomavirus (HPV) vaccines a barrier to global implementation, researchers have found that girls who received two doses of HPV vaccine had immune responses to HPV-16 and HPV-18 infection that were noninferior to (not worse than) the responses for young women who received three doses, according to a study in the May 1 issue of JAMA, a theme issue on child health. Contact: Brian Lin
Public Release: 30-Apr-2013
Nature ImmunologyT cells rely on 'rheostat' to help ensure that the immune response matches the threat A properly functioning immune system is a lesson in balance, providing protection against disease without attacking healthy tissue. Work led by St. Jude Children's Research Hospital scientists and published recently in Nature Immunology has identified a mechanism that helps T cells find that sweet spot where the strength of the immune response matches the threat.
National Institutes of Health, American-Lebanese-Syrian Associated Charities
Contact: Summer Freeman
Public Release: 30-Apr-2013
Proceedings of the National Academy of SciencesScientists find mutation driving pediatric brain tumors A type of low-grade but sometimes lethal brain tumor in children has been found in many cases to contain an unusual mutation that may help to classify, diagnose and guide the treatment of the tumors, report scientists at Dana-Farber Cancer Institute.
National Institutes of Health, Pediatric Low Grade Astrocytoma Foundation
Contact: Anne Doerr
Public Release: 30-Apr-2013
Cancer DiscoveryHow some cancers 'poison the soil' to block metastasis Cancer spread or metastasis can strike unprecedented fear in the minds of cancer patients. The "seed and the soil" hypothesis proposed by Stephen Paget in 1889 is now widely accepted to explain how cancer cells (seeds) are able to generate fertile soil (the microenvironment) in distant organs that promotes cancer's spread. However, this concept does not explain why some tumors do not spread or metastasize.
National Institutes of Health, Norwegian Cancer Society, Norwegian Research Council
Contact: Lauren Woods
Public Release: 30-Apr-2013
Journal of Thoracic OncologyChemo, radiation followed by surgery improves survival in lung cancer patients UI Health researchers report that a combination of chemotherapy and radiation followed by surgery in patients with stage 3 non-small cell lung cancer improves survival. Contact: Sherri McGinnis Gonzalez
Public Release: 30-Apr-2013
Nature CommunicationsDecoded: Molecular messages that tell prostate and breast cancers to spread Cancer cells are wily, well-traveled adversaries, constantly side-stepping treatments to stop their spread. But for the first time, scientists at the University of Michigan have decoded the molecular chatter that ramps certain cancer cells into overdrive and can cause tumors to metastasize throughout the body. Contact: Laura Bailey
Showing releases 151-175 out of 1210. << < 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 > >>
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