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Showing releases 151-175 out of 1216.

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Public Release: 10-Jul-2013
Journal of Controlled Release
Nanoparticles, 'pH phoresis' could improve cancer drug delivery
Researchers have developed a concept to potentially improve delivery of drugs for cancer treatment using nanoparticles that concentrate and expand in the presence of higher acidity found in tumor cells.
National Science Foundation

Contact: Emil Venere
venere@purdue.edu
765-494-4709
Purdue University

Public Release: 10-Jul-2013
Journal of American College of Cardiology
Location of body fat can elevate heart disease, cancer risk
Individuals with excessive abdominal fat have a greater risk of heart disease and cancer than individuals with a similar body mass index who carry their fat in other areas of the body, according to a study published online today in the Journal of the American College of Cardiology.

Contact: Nicole Napoli
nnapoli@acc.org
202-375-6523
American College of Cardiology

Public Release: 10-Jul-2013
Neurology
People with Alzheimer's disease may have lower risk of cancer and vice versa
Older people with Alzheimer's disease are less likely to also have cancer, and older people with cancer are less likely to also have Alzheimer's disease, according to the largest study to date on the topic, which appears in the July 10, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Contact: Rachel Seroka
rseroka@aan.com
612-928-6129
American Academy of Neurology

Public Release: 10-Jul-2013
Journal of the National Cancer Institute
Study confirms link between omega-3 fatty acids and increased prostate cancer risk
A second large, prospective study by scientists at Fred Hutchinson Cancer Research Center has confirmed the link between high blood concentrations of omega-3 fatty acids and an increased risk of prostate cancer.
NIH/National Cancer Institute, NIH/National Center for Complementary and Alternative Medicine

Contact: Kristen Woodward
kwoodwar@fhcrc.org
206-667-5095
Fred Hutchinson Cancer Research Center

Public Release: 9-Jul-2013
eLife
Tumor-suppressor Protein Gives Up Its Secrets
Genetic mutations aren't the only thing that can keep a protein called PTEN from doing its tumor-suppressing job. Johns Hopkins researchers have now discovered that four small chemical tags attached (reversibly) to the protein's tail can have the same effect, and they say their finding may offer a novel path for drug design to keep PTEN working.
NIH/National Cancer Institute, NIH/National Institute of General Medical Sciences

Contact: Catherine Kolf
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine

Public Release: 9-Jul-2013
Blood
Technologies for monitoring remaining leukemia after treatment may help predict patient outcomes
New evidence suggests that using advanced genetics technologies to monitor for remaining cancer cells after treatment may soon become an effective tool to inform treatment decisions and ultimately predict patient outcomes for patients with a particularly aggressive form of acute lymphocytic leukemia. Study results were published online today in Blood, the Journal of the American Society of Hematology.

Contact: Amanda Szabo
aszabo@hematology.org
202-552-4914
American Society of Hematology

Public Release: 9-Jul-2013
JAMA
Soy protein supplementation does not reduce risk of prostate cancer recurrence
Among men who had undergone radical prostatectomy, daily consumption of a beverage powder supplement containing soy protein isolate for 2 years did not reduce or delay development of biochemical recurrence of prostate cancer compared to men who received placebo, according to a study in the July 10 issue of JAMA.

Contact: Sherri McGinnis Gonzalez
smcginn@uic.edu
312-996-8277
The JAMA Network Journals

Public Release: 9-Jul-2013
Nature Genetics
Suspicions confirmed: Brain tumors in children have a common cause
An overactive signaling pathway is a common cause in cases of pilocytic astrocytoma, the most frequent type of brain cancer in children. This was discovered by a network of scientists coordinated by the German Cancer Research Center (as part of the International Cancer Genome Consortium, ICGC). In all 96 cases studied, the researchers found defects in genes involved in a particular pathway. Hence, drugs can be used to help affected children by blocking components of the signaling cascade.
German Cancer Aid, German Federal Ministry of Research and Education

Contact: Dr. Sibylle Kohlstädt
s.kohlstaedt@dkfz.de
Helmholtz Association of German Research Centres

Public Release: 9-Jul-2013
American Journal of Preventive Medicine
Physicians slow to implement HPV vaccination and cervical cancer screening guidelines
Recent breakthroughs in cervical cancer prevention have resulted in new vaccination and cervical cancer screening guidelines. Recommendations do not always translate into practice, however. Less than one-third of obstetrician-gynecologists vaccinate their eligible patients against the human papilloma virus, and only half adhere to cervical cancer prevention guidelines published three years previously, according to a survey published this month in the American Journal of Preventive Medicine.

Contact: Charlotte Seidman
eAJPM@ucsd.edu
858-534-9340
Elsevier Health Sciences

Public Release: 9-Jul-2013
PLOS ONE
MU researchers find condition in dogs that may help further research into human disease
Some people possess a small number of cells in their bodies that are not genetically their own; this condition is known as microchimerism. It is difficult to determine potential health effects from this condition because of humans' relatively long life-spans. Now, researchers at the University of Missouri have found that microchimerism can be found in dogs as well.

Contact: Nathan Hurst
hurstn@missouri.edu
573-882-6217
University of Missouri-Columbia

Public Release: 9-Jul-2013
ACS Medicinal Chemistry Letters
Sanford-Burnham researchers develop novel nanoparticle to deliver powerful RNA interference drugs
Silencing genes that have malfunctioned is an important approach for treating diseases such as cancer and heart disease. One effective approach is to deliver drugs made from small molecules of ribonucleic acid, or RNA, which are used to inhibit gene expression. The drugs, in essence, mimic a natural process called RNA interference.
National Institutes of Health

Contact: Deborah Robison
drobison@sanfordburnham.org
407-615-0072
Sanford-Burnham Medical Research Institute

Public Release: 9-Jul-2013
Journal of Endourology
Robotic ultrasound gives surgeon more direct control in mapping and removing kidney cancers
While the use of ultrasound to identify tumors during kidney cancer surgery is gaining acceptance, a research team at Henry Ford Hospital has successfully taken it a step further by showing an added benefit when the procedure is done robotically.
Henry Ford Hospital

Contact: Dwight Angell
dwight.angell@hfhs.org
313-850-3471
Henry Ford Health System

Public Release: 9-Jul-2013
American Journal of Preventive Medicine
Outdated practice of annual cervical-cancer screenings may cause more harm than good
For decades, women between the ages of 21 and 69 were advised to get annual screening exams for cervical cancer. In 2009, however, accumulating scientific evidence led major guideline groups to agree on a new recommendation that women be screened less frequently: every three years rather than annually.

Contact: Kathy Neal
kcneal@unc.edu
919-740-5673
University of North Carolina at Chapel Hill

Public Release: 8-Jul-2013
Health Affairs
Denormalizing smoking: Making the case for banning cigarettes in parks and on beaches
Many state and local governments banned smoking in parks and on beaches on the basis that passive smoke is a risk for non-smokers, cigarette butts pollute the environment, and seeing people smoke poses a long-term risk to children. Researchers at Columbia University say the evidence for these claims is far from definitive and policymakers pushing for smoking bans will need to make a stronger argument to overcome the opposition and gain the public trust.
American Legacy Foundation

Contact: Stephanie Berger
sb2247@columbia.edu
212-305-4372
Columbia University's Mailman School of Public Health

Public Release: 8-Jul-2013
Cancer Cell
New opportunities to treat bowel cancer
Researchers found that existing anticancer drugs, already on pharmacy shelves, may be effective against many cases of bowel cancer. The team uncovered the mutations that underlies bowel cancer in more than 120,000 patients worldwide and used this finding to identify existing drugs that target these processes. This study offers the opportunity to develop personalized treatments based on a person's genetic profile.
Wellcome Trust, Helmholtz Gemeinschaft

Contact: Aileen Sheehy
press.office@sanger.ac.uk
44-012-234-96928
Wellcome Trust Sanger Institute

Public Release: 8-Jul-2013
Annals of Family Medicine
July/August 2013 Annals of Family Medicine tip sheet
Three research studies and an accompanying editorial in the July/August issue of Annals of Family Medicine address the importance of shared decision making around prostate cancer screening. This tip sheet includes synopsis of all the original research articles featured in the current issue.

Contact: Angela Sharma
asharma@aafp.org
913-269-2269
American Academy of Family Physicians

Public Release: 8-Jul-2013
PLOS ONE
'Scent device' could help detect bladder cancer
Researchers from the University of Liverpool and University of the West of England have built a device that can read odors in urine to help diagnose patients with early signs of bladder cancer.

Contact: Samantha Martin
samantha.martin@liv.ac.uk
44-015-179-42248
University of Liverpool

Public Release: 8-Jul-2013
Health Affairs
Medicaid programs vary in coverage of preventive care, report says
Existing Medicaid beneficiaries have largely been left out of the health reform movement when it comes to preventive services that can ward off cancer, heart disease and other potentially deadly diseases, according to a new study by researchers at the George Washington University School of Public Health and Health Services.

Contact: Kathy Fackelmann
kfackelmann@gwu.edu
202-994-8354
George Washington University School of Public Health and Health Services

Public Release: 8-Jul-2013
Cancer
African-Americans with blood cancer do not live as long as Caucasians, despite equal care
A new analysis has found that among patients with chronic lymphocytic leukemia, African-Americans more commonly present with advanced disease, and they tend to have shorter survival times than Caucasians despite receiving the same care. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the results suggest that biological factors may account for some racial disparities in cancer survival.

Contact: Ben Norman
sciencenewsroom@wiley.com
44-012-437-70375
Wiley

Public Release: 8-Jul-2013
Proceedings of the National Academy of Sciences
What do rotten eggs and colon cancer have in common?
University of Texas Medical Branch at Galveston researchers have discovered that hydrogen sulfide -- the pungent-smelling gas produced by rotten eggs -- is a key player in colon cancer metabolism, and a potential target for therapies for the disease.
John Sealy Memorial Endowment Fund, American Heart Association, McLaughlin Foundation

Contact: Jim Kelly
jpkelly@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston

Public Release: 8-Jul-2013
Journal of Surgical Oncology
Nearly half of sarcoma surgeries done by nonsurgical oncology specialists
Orthopedic oncologists and surgical oncologists, who have been trained in the complex procedures required to remove sarcomas located deep in the muscles and other soft tissues of the limbs, conducted only 52 percent of these operations at 85 academic medical centers during a three-year period, according to an analysis of national data by UC Davis researchers.
University of California -- Davis Health System

Contact: Dorsey Griffith
dorsey.griffith@ucdmc.ucdavis.edu
916-734-9118
University of California - Davis Health System

Public Release: 8-Jul-2013
Journal of Cancer Therapy
Consuming soy peptide may reduce colon cancer metastasis
After a recent University of Illinois study showed that injection of the soy peptide lunasin dramatically reduced colon cancer metastasis in mice, the researchers were eager to see how making lunasin part of the animals' daily diet would affect the spread of the disease. "In this new study, we find that giving lunasin orally at 20 mg/kg of body weight reduced the number of metastatic tumors by 94 percent," said Elvira de Mejia, a U of I professor of food chemistry and food toxicology.
US Department of Agriculture

Contact: Phyllis Picklesimer
p-pickle@illinois.edu
217-244-2827
University of Illinois College of Agricultural, Consumer and Environmental Sciences

Public Release: 8-Jul-2013
Journal of Clinical Investigation
Inhibiting macrophage MerTK signaling creates an innate immune response against cancer
New evidence by a University of North Carolina-led team shows that MerTK macrophage action in the microenvironment that surrounds cancer cells blunts the immune response, allowing the tumor cell to grow and metastasize.
Breast Cancer Research Foundation

Contact: William Davis
william_davis@med.unc.edu
910-232-6264
University of North Carolina Health Care

Public Release: 8-Jul-2013
Cancer Cell
New anti-cancer compound shows promise for breast cancer
Melbourne researchers have discovered that anti-cancer compounds currently in clinical trials for some types of leukaemia could offer hope for treating the most common type of breast cancer. The researchers, from the Walter and Eliza Hall Institute, found that the compounds, called BH3-mimetics, were effective in treating aggressive oestrogen receptor-positive (ER-positive) breast cancers when combined with the breast cancer drug tamoxifen in preclinical models. Approximately 70 per cent of breast cancers are ER-positive.
National Health and Medical Research Council, Australian Cancer Research Foundation, National Breast Cancer Foundation, Qualtrough Family Bequest, Victorian Government

Contact: Liz Williams
williams@wehi.edu.au
61-428-034-089
Walter and Eliza Hall Institute

Public Release: 8-Jul-2013
Proceedings of the National Academy of Sciences
Cancer research brief: Targeting pancreatic cancer drug resistance
In an effort to combat drug resistance in pancreatic cancer, researchers have been investigating methods to enhance chemotherapy. Previously it was thought that using molecules that help open up the tumors, thus allowing better access for medicines, was the most likely way to do this. Professor David Tuveson's team at Cold Spring Harbor Laboratory now show that inhibiting survival cues that the cancer cells rely on to stay alive increases the effectiveness of chemotherapy.
Cancer Research UK, Lustgarten Foundation

Contact: Edward Brydon
ebrydon@cshl.edu
516-367-6822
Cold Spring Harbor Laboratory

Showing releases 151-175 out of 1216.

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