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Showing releases 176-200 out of 1124. << < 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 > >>
Public Release: 6-Nov-2012
 PLOS MedicineNIH study finds leisure-time physical activity extends life expectancy as much as 4.5 years Leisure-time physical activity is associated with longer life expectancy, even at relatively low levels of activity and regardless of body weight, according to a study by a team of researchers led by the National Cancer Institute , part of the National Institutes of Health. The study, which found that people who engaged in leisure-time physical activity had life expectancy gains of as much as 4.5 years, appeared Nov. 6, 2012, in PLOS Medicine. 
NIH/National Cancer Institute, NIH/National Human Genome Research Institute
Contact: NCI Press Office
Public Release: 6-Nov-2012
PLOS MedicineStrong tobacco control policies in Brazil credited for more than 400,000 lives saved Brazil's tobacco control policies are credited for more than 400,000 lives saved and a 50 percent reduction in smoking between 1989 and 2010. Those policies include high cigarette prices, smoke-free air laws, marketing restrictions and graphic warnings on cigarette packages. Adding to the dramatic conclusion of the study, the researchers say Brazil's policies could result in as many as seven million lives saved by 2050.
NIH/National Cancer Institute, Bloomberg Philanthropies
Contact: Karen Mallet
Public Release: 5-Nov-2012
Annals of Internal MedicineEmbargoed news from Annals of Internal Medicine Below is information about an article being published in the Nov. 6 issue of Annals of Internal Medicine. The information is not intended to substitute for the full article as a source of information. Annals of Internal Medicine attribution is required for all coverage. Contact: Megan Hanks
Public Release: 5-Nov-2012
Proceedings of the National Acadamy of SciencesFirst gene therapy study in human salivary gland shows promise This finding comes from the first-ever Phase I clinical study of gene therapy in a human salivary gland. Its results show that the transferred gene, Aquaporin-1, has great potential to help head and neck cancer survivors who battle with chronic dry mouth. Aquaporin-1 encodes a protein that naturally forms pore-like water channels in the membranes of cells to help move fluid, such as occurs when salivary gland cells secrete saliva into the mouth.
NIH/National Institute of Dental and Craniofacial Research
Contact: Bob Kuska
Public Release: 5-Nov-2012
PLOS ONEInhibition of enzyme NOX4 prevents liver fibrosis Researchers at the Bellvitge Biomedical Research Institute have led a study published in PLOS ONE showing that the inhibition of a family member of NADPH oxidase enzyme, NOX4, plays an important role in liver fibrosis. Contact: Raül Toran
Public Release: 5-Nov-2012
International Journal of CancerScientists find Achilles’ heel of cancer cells Scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum) and Heidelberg University Hospital have identified the HDAC11 enzyme as a promising target for new cancer therapies. If this molecule is turned off, cancer cells stop growing and die. Contact: Anke Retzmann
Public Release: 5-Nov-2012
Proceedings of the National Academy of SciencesResearchers discover how underground rodent wards off cancer Biologists at the University of Rochester have determined how blind mole rats fight off cancer--and the mechanism differs from what they discovered three years ago in another long-lived and cancer-resistant mole rat species, the naked mole rat.
National Institutes of Health, Ellison Medical Foundation
Contact: Peter Iglinski
Public Release: 2-Nov-2012
European UrologyActive surveillance can reduce suffering among men with prostate cancer With active surveillance many men with prostate cancer could dispense with radiation treatment and surgery, and thus avoid adverse effects such as incontinence and impotence. Contact: Rebecka Arnsrud Godtman
Public Release: 2-Nov-2012
Cancer ResearchNew finding gives clues for overcoming tamoxifen-resistant breast cancer A University of Cincinnati cancer biology team reports breakthrough findings about specific cellular mechanisms that may help overcome endocrine (hormone) therapy-resistance in patients with estrogen-positive breast cancers, combating a widespread problem in effective medical management of the disease. The team has identified a specific estrogen receptor co-activator--known as MED1--as playing a central role in mediating tamoxifen resistance in human breast cancer.
National Institutes of Health, University of Cincinnati Cancer Institute, Ride Cincinnati/Marlene Harris Pilot Grant, Susan G. Komen
Contact: Amanda Harper
Public Release: 2-Nov-2012
Nucleic Acids ResearchCancer bound PAHs are common environmental pollutants found in automobile exhaust, barbequed foods and tobacco smoke. These molecules are converted into carcinogens in the body that attack DNA and cause cancer-inducing mutations. Contact: Aaron Dubrow
Public Release: 1-Nov-2012
Cell Stem CellStem cells show promise for treating infertility in cancer patients A promising stem-cell-based approach for treating infertility has been successfully demonstrated in non-human primates, as reported in a study published by Cell Press in the November issue of the journal Cell Stem Cell. The preclinical study represents an important milestone for translating this strategy to the clinic, particularly for cancer survivors who have been rendered infertile by chemotherapy they received before reaching sexual maturity. Contact: Elisabeth (Lisa) Lyons
Public Release: 1-Nov-2012
Journal of NeurosurgeryStudy: Repeated surgeries appear to extend life of patients with deadliest of brain cancers People who undergo repeated surgeries to remove glioblastomas -- the most aggressive and deadliest type of brain tumors -- may survive longer than those who have just a one-time operation, new Johns Hopkins research suggests. Contact: Stephanie Desmon
Public Release: 1-Nov-2012
Cell Stem CellFeedback loop maintains basal cell population Notch -- the protein that can help determine cell fate -- maintains a stable population of basal cells in the prostate through a positive feedback loop system with another key protein -- TGF beta (transforming growth factor beta), said Baylor College of Medicine researchers in the journal Cell Stem Cell. Contact: Dipali Pathak
Public Release: 1-Nov-2012
Cell Stem CellMale fertility can be restored after cancer treatment, says Pitt team An injection of banked sperm-producing stem cells can restore fertility to males who become sterile due to cancer drug side effects, according to researchers at the University of Pittsburgh School of Medicine and Magee-Womens Research Institute. In their animal study, which was published today in Cell Stem Cell, previously frozen stem cells restored production of sperm that successfully fertilized eggs to produce early embryos.
National Institutes of Health, Magee-Womens Research Institute and Foundation, Richard King Mellon Foundation
Contact: Anita Srikameswaran
Public Release: 1-Nov-2012
Journal of Clinical InvestigationJCI early table of contents for Nov. 1, 2012 This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, November 1, 2012, in the JCI: Congenital diarrheal disorder linked to a mutation in DGAT1; Feel the burn: natriuretic peptides enhance human skeletal muscle metabolism; Improved detection of polyomavirus in Merkel cell carcinoma; Pumping iron to develop red blood cells; Finding the inflammatory culprit in a mouse model of multiple sclerosis; and many more. Contact: Jillian Hurst
Public Release: 1-Nov-2012
Proceedings of the National Academies of Science Early EditionA protein’s role in helping cells repair DNA damage In a new study, University at Buffalo scientists describe the role that a protein called TFIIB plays in helping cells repair DNA damage, a critical function for preventing the growth of tumors.
NIH/National Institute of General Medical Sciences
Contact: Charlotte Hsu
Public Release: 1-Nov-2012
ScienceGene switch important in cancer discovered Scientists at Karolinska Institutet in Sweden and the University of Helsinki in Finland have shown that the "switches" that regulate the expression of genes play a major role in the development of cancer. In a study, published in Science, they have investigated a gene region that contains a particular single nucleotide variant associated with increased risk for developing colorectal and prostate cancers -- and found that removing this region caused dramatic resistance to tumor formation.
EU FP7 Health, Science for Life Laboratory, European Reasearch Council
Contact: Karolinska Institutet Press Office
Public Release: 1-Nov-2012
NatureBigger human genome pool uncovers rarer variants Thanks to powerful computational tools developed at Simon Fraser University, more than 100 scientists from around the world have genetically mapped the largest and most varied number of human genomes to date. The researchers used computational tools to discover many variants in those genomes. Their findings have just been published in the Nature journal article An integrated map of genetic variation from 1,092 human genomes now online. Contact: Carol Thorbes
Public Release: 1-Nov-2012
Cancer ResearchUC Davis scientists identify new target for lung cancer treatment A team of UC Davis investigators has discovered a protein on the surface of lung cancer cells that could prove to be an important new target for anti-cancer therapy. A series of experiments in mice with lung cancer showed that specific targeting of the protein with monoclonal antibodies reduced the size of tumors, lowered the occurrence of metastases and substantially lengthened survival time.
deLeuze Family Endowment for a Non-Toxic Cure for Lymphoma
Contact: Dorsey Griffith
Public Release: 1-Nov-2012
Proceedings of the National Academy of SciencesCombination treatment may improve survival of breast cancer patients with brain metastases Adding an angiogenesis inhibitor to treatment with a HER2-inhibiting drug could improve outcomes for patients with HER2-positive breast cancer who develop brain metastases. In their report published online in PNAS Plus, Massachusetts General Hospital investigators report the first preclinical study combining antiangiogenic and anti-HER2 drugs in an animal model of brain metastatic breast cancer.
NIH/National Cancer Institute, US Department of Defense
Contact: Sue McGreevey
Public Release: 1-Nov-2012
Integrative BiologyResearchers use blood testing to predict level of enzymes that facilitate disease progression Researchers are developing a technique for predicting from a simple blood sample the amount of cathepsins -- protein-degrading enzymes known to accelerate certain diseases -- a specific person would produce. This patient-specific information may be helpful in developing personalized approaches to treat these tissue-destructive diseases.
National Institutes of Health
Contact: John Toon
Public Release: 1-Nov-2012
George Mason University researchers target breast cancer in 3 trials Researchers at George Mason University are attacking breast cancer in three separate trials, including one that uses a malarial drug that shows promise as a way to stop breast cancer before it starts.
National Institutes of Health, Department of Defense Breast Cancer Research Project, Side-Out Foundation
Contact: Michele McDonald
Public Release: 1-Nov-2012
Journal of Biomedical OpticsLaser-light testing of breast tumor fiber patterns helps show whose cancer is spreading Using advanced microscopes equipped with tissue-penetrating laser light, cancer imaging experts at Johns Hopkins have developed a promising, new way to accurately analyze the distinctive patterns of ultra-thin collagen fibers in breast tumor tissue samples and to help tell if the cancer has spread. Contact: David March
Public Release: 1-Nov-2012
Human MutationGenetic test results for Lynch syndrome improved with new computer program Genetic testing for Lynch syndrome, a hereditary predisposition to colon cancer, often proves inconclusive, but two new studies show that two-thirds to three-fourths of genetic variants can be classified into the categories that indicate the most appropriate screening and treatment guidelines. Contact: Linda Aagard
Public Release: 1-Nov-2012
Lancet OncologyIU researchers report first effective treatment of tumors arising from common genetic disease NF1 Physician-researchers at Indiana University School of Medicine have reported the first effective therapy for a class of previously untreatable and potentially life-threatening tumors often found in children.
National Institutes of Health, IU Simon Cancer Center, Wells Center for Pediatric Research
Contact: Eric Schoch
Showing releases 176-200 out of 1124. << < 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 > >>
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