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Showing releases 176-200 out of 1303.

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Public Release: 4-Aug-2015
Nature Communications
Molecular tinkering doubles cancer drug's efficacy
Researchers at Duke University have molecularly repackaged a widely used cancer drug called paclitaxel, more than doubling its effectiveness at destroying tumors than the current gold-standard pharmaceutical, Abraxane.
National Institutes of Health

Contact: Ken Kingery
ken.kingery@duke.edu
919-660-8414
Duke University

Public Release: 4-Aug-2015
Journal of Clinical Investigation
Key protein drives 'power plants' that fuel cells in heart and other key body systems
Case Western Reserve University scientists have discovered that a protein called Kruppel-like Factor 4 (KLF4) controls mitochondria -- the 'power plants' in cells that catalyze energy production. Specifically, they determined KLF4's pivotal role through its absence -- that is, the mitochondria malfunction without enough of the protein, which in turn leads to reduced energy. The researchers' findings appear in the August edition of The Journal of Clinical Investigation.
National Institutes of Health, American Heart Association

Contact: Jeannette Spalding
Jeannette.Spalding@case.edu
216-368-3004
Case Western Reserve University

Public Release: 4-Aug-2015
British Journal of Cancer
England still struggling to close the gap in cancer survival
Cancer survival in England remains lower than countries with similar healthcare systems, according to a new Cancer Research UK funded study published in the British Journal of Cancer today.
Cancer Research UK

Contact: Stephanie McClellan
stephanie.mcclellan@cancer.org.uk
020-346-95314
Cancer Research UK

Public Release: 4-Aug-2015
Cancer Epidemiology, Biomarkers & Prevention
Exercise during teen years linked to lowered risk of cancer death later
Women who exercised during their teen years were less likely to die from cancer and all other causes during middle-age and later in life, according to a new study by investigators at Vanderbilt University Medical Center and the Shanghai Cancer Institute in China.
National Institutes of Health

Contact: Craig Boerner
craig.boerner@vanderbilt.edu
615-322-4747
Vanderbilt University Medical Center

Public Release: 3-Aug-2015
Nature Cell Biology
MD Anderson study reveals new insight into DNA repair
DNA double-strand breaks are the worst possible form of genetic malfunction that can cause cancer and resistance to therapy.

Contact: Ron Gilmore
rlgilmore1@mdanderson.org
713-745-1898
University of Texas M. D. Anderson Cancer Center

Public Release: 3-Aug-2015
Plastic and Reconstructive Surgery
FAU student and surgeon collaborate on new, alternative procedure to radical mastectomy
Elizabeth Hopkins has spent more than 640 hours shadowing Hilton Becker, M.D., a plastic and reconstructive surgeon. In 2014, she had a double mastectomy as a preventive measure, using a revolutionary procedure that is an alternative to radical mastectomy. This new procedure developed by Becker is done minimally invasively and spares the skin, nipple and areola.

Contact: Gisele Galoustian
ggaloust@fau.edu
561-297-2676
Florida Atlantic University

Public Release: 3-Aug-2015
Clinical Cancer Research
Urine test for early stage pancreatic cancer possible after biomarker discovery
A combination of three proteins found at high levels in urine can accurately detect early-stage pancreatic cancer, UK researchers have found. The discovery could lead to a non-invasive, inexpensive test to screen people at high risk of developing the disease.
Pancreatic Cancer Research Fund

Contact: Becky Tanner
beckytanner@pcrf.org.uk
44-020-836-01119
Pancreatic Cancer Research Fund

Public Release: 3-Aug-2015
Nature Communications
Combination therapy may be more effective against the most common ovarian cancer
High-grade serous ovarian cancer often responds well to the chemotherapy drug carboplatin, but why it so frequently comes back after treatment has been a medical mystery.
American Cancer Society, NIH/National Cancer Institute, NIH/National Center for Advancing Translational Science UCLA Clinical Translational Science Institute

Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-794-2262
University of California - Los Angeles Health Sciences

Public Release: 3-Aug-2015
Nature Genetics
Further evidence of genetic key to deadliest form of skin cancer
Scientists from the University of Leeds have uncovered further evidence that the protective buffers at the ends of chromosomes -- known as telomeres -- are fundamental to the understanding of the deadliest form of skin cancer, melanoma.
Cancer Research UK, National Institutes of Health

Contact: Ben Jones
B.P.Jones@leeds.ac.uk
44-011-334-38059
University of Leeds

Public Release: 3-Aug-2015
Molecular Cell
Tel Aviv University researcher discovers trigger of deadly melanoma
Tel Aviv University researcher Dr. Carmit Levy has discovered the trigger that causes melanoma cancer cells to turn lethal.

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University

Public Release: 3-Aug-2015
Nature Medicine
Potential new therapy approaches to reverse kidney damage identified
Adults who are worried or terrified sometimes curl up into a fetal position. Likewise, adult cells that are injured, including genetic injury leading to cancer, initiate a process that was present during embryonic development.

Contact: Ron Gilmore
rlgilmore1@mdanderson.org
713-745-1898
University of Texas M. D. Anderson Cancer Center

Public Release: 3-Aug-2015
Journal of Investigative Dermatology
Veterans returning from Middle East face higher skin cancer risk
Soldiers who served in the glaring desert sunlight of Iraq and Afghanistan returned home with an increased risk of skin cancer, due not only to the desert climate, but also a lack of sun protection, Vanderbilt dermatologist Jennifer Powers, M.D., reports in a study published recently in the Journal of Investigative Dermatology.
Skin Cancer Foundation, NIH/National Center for Advancing Translational Science

Contact: Craig Boerner
craig.boerner@vanderbilt.edu
615-322-4747
Vanderbilt University Medical Center

Public Release: 3-Aug-2015
Future Science OA
Are animal models still essential to biological research?
Future Science Group today announced the publication of a new article in Future Science OA, covering the use of animal models in scientific research.

Contact: Leela Ripton
l.ripton@future-science-group.com
44-208-371-6090
Future Science Group

Public Release: 3-Aug-2015
American Journal of Epidemiology
Yo-yo dieting not associated with increased cancer risk
The first comprehensive study of its kind finds weight cycling, repeated cycles of intentional weight loss followed by regain, was not associated with overall risk of cancer in men or women.
American Cancer Society

Contact: David Sampson
david.sampson@cancer.org
American Cancer Society

Public Release: 3-Aug-2015
Technology
Scaffold-integrated microchips for end-to-end in vitro tumor cell attachment and xenograft formation
A team of researchers from Massachusetts General Hospital, Florida State University, and University of Massachusetts has developed a new microchip that can retrieve microfluidically attached cancer cells for serial analysis by integrating a 3-D hydrogel scaffold into a fluidic device. The researchers describe their approach in the forthcoming issue of the journal TECHNOLOGY.
National Institute of Health, and Shriners Hospitals for Children

Contact: Philly Lim
mllim@wspc.com
65-646-65775
World Scientific

Public Release: 3-Aug-2015
Nature Communications
Stress responder is a first responder in helping repair DNA damage and avoiding cancer
DNA damage increases the risk of cancer, and researchers have found that a protein, known to rally when cells get stressed, plays a critical, early step in its repair.
National Institutes of Health

Contact: Toni Baker
tbaker@gru.edu
706-721-4421
Medical College of Georgia at Georgia Regents University

Public Release: 3-Aug-2015
Chemical Science
Molecular spies to fight cancer
Scientists at Helmholtz-Zentrum Dresden-Rossendorf, together with colleagues at the University of Zurich and the Ruhr-Universität Bochum, have for the first time successfully tested a new tumor diagnosis method under near-real conditions. The procedure first sends out an antibody as a 'spy' to detect the diseased cells and binds to them. This antibody in turn attracts a subsequently administered radioactively labeled probe. The scientists could then clearly visualize the tumor by utilizing a tomographic method.

Contact: Simon Schmitt
s.schmitt@hzdr.de
49-351-260-3400
Helmholtz-Zentrum Dresden-Rossendorf

Public Release: 3-Aug-2015
New England Journal of Medicine
Irradiation of regional nodes in stage I - III breast cancer patients affects overall survival
At a median follow-up of 10.9 years, an EORTC study has shown that irradiation of regional nodes in patients with stage I, II, or III breast cancer has a marginal effect on overall survival, the primary endpoint (at 10 years, overall survival was 82.3 percent for regional irradiation versus 80.7 percent for no regional irradiation).

Contact: John Bean
john.bean@eortc.be
European Organisation for Research and Treatment of Cancer

Public Release: 1-Aug-2015
Cancer Research
Childhood cancer cells drain immune system's batteries
Cancer cells in neuroblastoma contain a molecule that breaks down a key energy source for the body's immune cells, leaving them too physically drained to fight the disease, according to new research published in the journal Cancer Research today.
Cancer Research UK

Contact: Greg Jones
greg.jones@cancer.org.uk
020-346-98311
Cancer Research UK

Public Release: 31-Jul-2015
Cancer Epidemiology, Biomarkers & Prevention
Exercise during adolescence linked to lowered risk of death later
Women who participated in exercise as adolescents had a reduced risk of death from cancer and all causes in their middle and older ages.
National Institutes of Health

Contact: Lauren Riley
lauren.riley@aacr.org
215-446-7155
American Association for Cancer Research

Public Release: 31-Jul-2015
Basel Life Science Week 2015
Findings in research on photoaging could reverse negative impact of ultraviolet radiation
Photoaging is a process that occurs when human skin is exposed to UV radiation from the sun that causes it to age at a faster rate than it would under normal circumstances. Though the process is known to occur how it works is not fully understood. InSilico Medicine's GeroscopeTM software provided insights into this process that could help to combat it. The research will be presented at Basel Life Science Week 2015.

Contact: Qingsong Zhu
zhu@insilicomedicine.com
443-451-7212
InSilico Medicine, Inc.

Public Release: 31-Jul-2015
Breast Cancer Research
Researchers identify new cancer marker and possible therapeutic target for breast cancer
A new way to detect -- and perhaps treat -- one of the deadliest types of breast cancer has been found. Led by researchers at Boston University School of Medicine, the study appears online in Breast Cancer Research.
Research Promotion Foundation of Cyprus, Susan G. Komen for the Cure Foundation, National Institutes of Health

Contact: Gina DiGravio
ginad@bu.edu
617-638-8480
Boston University Medical Center

Public Release: 31-Jul-2015
PLOS ONE
Watching a tumor grow in real-time
The ability to visualize and characterize the composition of a tumor in detail during its development can provide valuable insights in order to target appropriate therapeutics. The polymer chemist Professor Dr. Prasad Shastri and the pharmacist Jon Christensen, in collaboration with the biomedical researcher Dr. Daniel Vonwil, from the University of Freiburg have visualized and quantified the growth and composition of breast tumors over time in a living animal. The researchers published their findings in a paper in the journal PLOS ONE.

Contact: Katrin Albaum
katrin.albaum@bioss.uni-freiburg.de
49-761-203-97662
BIOSS - Centre for Biological Signalling Studies

Public Release: 30-Jul-2015
European Journal of Cancer Care
Cancer patients lose faith in healthcare system if referred late by GP
If it takes more than three trips to the GP to be referred for cancer tests, patients are more likely to be dissatisfied with their overall care, eroding confidence in the doctors and nurses who go on to treat and monitor them.
Cancer Research UK

Contact: Stephanie McClellan
stephanie.mcclellan@cancer.org.uk
020-346-95314
Cancer Research UK

Public Release: 30-Jul-2015
JAMA Oncology
Mouth rinse could help predict recurrence of HPV-related oropharyngeal cancers
Oropharyngeal cancer patients who were found to have detectable traces of human papillomavirus type 16 (HPV16) in their saliva following cancer treatment are at an increased risk for recurrence, a study led by researchers at the Johns Hopkins Bloomberg School of Public Health has found.
Oral Cancer Foundation, NIH/National Institute of Dental and Craniofacial Research, National Institutes of Health

Contact: Barbara Benham
bbenham1@jhu.edu
Johns Hopkins University Bloomberg School of Public Health

Showing releases 176-200 out of 1303.

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