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Showing releases 176-200 out of 1216. << < 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 > >>
Public Release: 8-Jul-2013
 Journal of Clinical InvestigationRemoval of tumor-associated immune cell protein decreases tumor progression In this issue of the Journal of Clinical Investigation, Shelley Earp and colleagues at the University of North Carolina a Chapel Hill demonstrate that removal of the protein MerTK from immune cells decreased tumor growth in mouse models of breast cancer, melanoma, and colon cancer. 
National Institutes of Health, Breast Cancer Research Foundation, University of North Carolina/Breast Cancer SPORE
Contact: Corinne Williams
Public Release: 8-Jul-2013
Cancer CellTargeting errant immune system enzyme kills myelodysplastic cells Scientists have successfully targeted a malfunctioning immune system enzyme to kill diseased cells from patients with myelodysplastic syndrome -- a blood disorder and precursor to leukemia. Reporting their results July 8 in Cancer Cell, researchers say their successful laboratory tests in human MDS cells and mouse models of MDS provide a molecular target for designing new drugs to battle a syndrome with few effective treatments.
National Institues of Health, American Society of Hematology, Department of Defense
Contact: Nick Miller
Public Release: 8-Jul-2013
Journal of Clinical InvestigationJCI early table of contents for July 8, 2013 This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, July 8, 2013, in the JCI: Immune cells play a role in early pregnancy; Removal of tumor-associated immune cell protein decreases tumor progression; and many more. Contact: Corinne Williams
Public Release: 7-Jul-2013
Nature MedicineSugar makes cancer light-up in MRI scanners A new technique for detecting cancer by imaging the consumption of sugar with magnetic resonance imaging has been unveiled by UCL scientists. The breakthrough could provide a safer and simpler alternative to standard radioactive techniques and enable radiologists to image tumors in greater detail.
Cancer Research UK, Engineering and Physical Sciences Research Council, British Heart Foundation
Contact: David Weston
Public Release: 7-Jul-2013
Nature Chemical BiologyScientists decipher cellular 'roadmap' of disease-related proteins University of Toronto researchers are helping demystify an important class of proteins associated with disease, a discovery that could lead to better treatments for cancer, cystic fibrosis and many other conditions. Contact: Suniya Kukaswadia
Public Release: 4-Jul-2013
PLOS ONENew research could pave the way to safer treatments for arthritis The increased risk of heart attack or stroke associated with many arthritis drugs may be avoidable, according to a new international study co-authored by researchers at Imperial College London.
Wellcome Trust
Contact: Gilead Amit
Public Release: 4-Jul-2013
Bioconjugate ChemistryNew marker substance for cancer cells Scientists from ETH Zurich have developed a new substance that enables certain tumour types to be rendered visible in high resolution using positron emission tomography. The so-called tracer has successfully been tested in mice. Now the researchers are planning clinical trials in humans. Contact: Roger Schibli
Public Release: 3-Jul-2013
15th ESMO WORLD CONGRESS on GASTROINTESTINAL CANCER Annals of OncologyStudy confirms adding chemotherapy to surgery improves survival in advanced gastric cancer At the meeting Prof Sung Hoon Noh, a gastric surgeon from Yonsei University College of Medicine, Korea, presented 5-year follow-up from the phase III CLASSIC trial, which added combination chemotherapy to a standard surgical procedure called D2 gastrectomy. The chemotherapy regimen studied in the trial is called XELOX, which is a combination of the drugs capecitabine and oxaliplatin. Contact: ESMO Press Office
Public Release: 3-Jul-2013
Science Translational MedicineImproved outlook for immune-based therapies The idea of fighting infections and even cancers by inducing protective immune responses may now be a step closer to clinical practice. Researchers have removed a major obstacle to widespread use of adoptive transfer therapy, in which a patient receives "killer" immune cells targeting a disease agent. Existing technologies can easily provide antigen-specific T cells, but it has been challenging to identify those individual cells most likely to fight disease effectively -- until now.
German Research Foundation, Technische Universitat Munchen Institute for Advanced Study
Contact: Patrick Regan
Public Release: 3-Jul-2013
CellScientists identify gene that controls aggressiveness in breast cancer cells Whitehead Institute researchers have determined that in basal breast cancer cells a transcription factor known as ZEB1 is held in a poised state, ready to increase the cells' aggressiveness and enable them to transform into cancer stem cells capable of seeding new tumors throughout the body. Intriguingly, luminal breast cancer cells, which are associated with a much better clinical prognosis, carry this gene in a state in which it seems to be permanently shut down.
National Institutes of Health, Vertex Scholars Program, National Science Foundation, Jerome and Florence Brill Fellowship, Croucher and Ludwig Research Fellowship
Contact: Nicole Rura
Public Release: 3-Jul-2013
Cancer Epidemiology, Biomarkers & PreventionMoms often talk to children about the results of cancer genetic testing Mothers commonly talk to their children about genetic test results even if they test positive for a BRCA1 or BRCA2 gene mutation, which sharply increases a woman's risk of developing breast and ovarian cancer. That is among the findings of a new study, which also suggests mothers who don't discuss their test results are unsatisfied with that decision.
National Human Genome Research Institute
Contact: Karen Mallet
Public Release: 3-Jul-2013
LancetSingle men, smokers at higher risk for oral human papillomavirus infection, Moffitt study shows Smokers and single men are more likely to acquire cancer-causing oral human papillomavirus (HPV), according to new results from the HPV Infection in Men Study. Researchers from Moffitt Cancer Center, the National Cancer Institute, Mexico and Brazil also report that newly acquired oral HPV infections in healthy men are rare and when present, usually resolve within one year.
NIH/National Cancer Institute
Contact: Kim Polacek
Public Release: 3-Jul-2013
CellNew papers identify a microRNA that drives both cancer onset and metastasis A mere 25 years ago, noncoding RNAs were considered nothing more than "background noise" in the overall genomic landscape. Now, two new studies reveal that one of these tiny noncoding molecules -- microRNA-22 -- plays an outsized role in two types of cancer.
National Institutes of Health
Contact: Bonnie Prescott
Public Release: 3-Jul-2013
American Journal of PathologyCancer-linked FAM190A gene found to regulate cell division Johns Hopkins cancer scientists have discovered that a little-described gene known as FAM190A plays a subtle but critical role in regulating the normal cell division process known as mitosis, and the scientists' research suggests that mutations in the gene may contribute to commonly found chromosomal instability in cancer.
NIH/National Cancer Institute
Contact: Vanessa Wasta
Public Release: 3-Jul-2013
Cell ReportsDiscovered the role of noncoding 5S rRNA in protecting the p53 tumor suppressor gene Researchers of the Cancer Metabolism group at the IDIBELL and the University of Cincinnati, led by George Thomas, have discovered a role for ribosomal 5S RNA in the formation of a complex that regulates the stability of p53. Normally, p53 prevents healthy cells from becoming tumorigenic. The results have been published in the online edition of Cell Reports. Contact: Arantxa Mena
Public Release: 3-Jul-2013
15th ESMO WORLD CONGRESS on GASTROINTESTINAL CANCER Annals of OncologyImmune-boosting colorectal cancer drug shows promise The findings confirm the biological action of the drug called MGN1703 and suggest it may be possible to identify which gastrointestinal cancer patients will benefit most from the treatment, reported Prof Hans-Joachim Schmoll from Martin Luther University, Halle, Germany. Contact: ESMO Press Office
Public Release: 3-Jul-2013
Cancer CellGateway for metastases Activated blood platelets enable cancer cells to penetrate blood vessels. Contact: Dr. Stefan Offermanns
Public Release: 2-Jul-2013
Journal of Biological ChemistryChanges in hyaluronan metabolism key in adaptation of keratinocytes to radiation injury As the outermost layer of skin, epidermis is crucial in forming a permeability barrier and protection against various environmental agents. Thus, investigating the biology of its most important cell type, the keratinocyte, is key to understanding the effects of solar ultraviolet radiation in skin, and helps design effective means of protection against excessive exposure. Contact: Leena Rauhala
Public Release: 2-Jul-2013
StructureA potentially life-saving protein takes shape The protein ubiquitin, found in all membranous cells, may hold the key to treating diseases from cancer to Parkinson's. Structural biologists at the University of Maryland College Park examine an omnipresent but rarely studied form of ubiquitin, the polymeric ubiquitin chains linked by the animo acid Lysine-11. The team finds these chains are remarkably flexible and probably multi-functional. Contact: Heather Dewar
Public Release: 2-Jul-2013
Journal of Clinical InvestigationHijacking stress response in cancer NRF2 works as a "master gene" that turns on stress response by increasing numerous antioxidants and pollutant-detoxifying genes to protect the lungs from variety of air pollutants such as diesel exhaust and cigarette smoke. However, researchers at the Johns Hopkins Bloomberg School of Public Health and others have found for the first time that NRF2 signaling also plays a role in the growth of tumor cells by altering metabolic pathways.
NIH/National Cancer Institute, NIH/National Institute of Environmental Sciences
Contact: Tim Parsons
Public Release: 2-Jul-2013
PLOS ONEHow cancer spreads: Metastatic tumor a hybrid of cancer cell and white blood cell Yale Cancer Center scientists, together with colleagues at the Denver Police Crime Lab and the University of Colorado, have found evidence that a human metastatic tumor can arise when a leukocyte (white blood cell) and a cancer cell fuse to form a genetic hybrid.
NIH/National Cancer Institute, Amway Corporation-University of Colorado Cancer Center
Contact: Karen N. Peart
Public Release: 1-Jul-2013
Journal of Thoracic OncologyResearchers use immunocytochemistry to determine ALK status Now research published in the August issue of the Journal of Thoracic Oncology, says ALK immunocytochemistry is highly accurate for detecting ALK-rearranged non-small cell lung cancer on cytological specimens. Contact: Kristal Griffith
Public Release: 1-Jul-2013
Journal of Thoracic OncologyResearchers find 2 new methods to determine ALK status Now research published in the August issue of the Journal of Thoracic Oncology, describes the development and evaluation of two new methodologies. Contact: Kristal Griffith
Public Release: 1-Jul-2013
Journal of Thoracic OncologyStudy shows SBRT for stage I NSCLC safe and effective Their research, published in the August issue of the Journal of Thoracic Oncology, concludes SBRT for stage I NSCLC was safe and effective in this multi-institutional environment. In addition, radiotherapy dosage was identified as a major treatment factor influencing local tumor control and overall survival. Contact: Kristal Griffith
Public Release: 1-Jul-2013
Nature MedicineResearchers pinpoint sources of fibrosis-promoting cells that ravage organs Scientists have tracked down and quantified the diverse origins of cells that drive fibrosis, the incurable, runaway wound-healing that scars and ultimately destroys organs such as the lungs, liver and kidneys. Contact: Scott Merville
Showing releases 176-200 out of 1216. << < 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 > >>
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