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Showing releases 176-200 out of 1427.

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Public Release: 30-Jun-2016
JAMA Oncology
BRCA1 mutations linked to increased risk of serous, serous-like endometrial cancer
Increased risk for aggressive serous/serous-like endometrial cancer was increased in women with BRCA1 mutations, although the overall risk for uterine cancer after risk-reducing salpingo-oophorectomy (RRSO) to remove the fallopian tube and ovary was not increased, according to a new study published online by JAMA Oncology.

Contact: Sarah Avery
sarah.avery@duke.edu
919-660-1306
The JAMA Network Journals

Public Release: 30-Jun-2016
Cell Reports
Study finds potential treatment for non-alcoholic fatty liver disease
Researchers report in the journal Cell Reports a targeted molecular therapy that dramatically reduces the initial development of non-alcoholic fatty liver disease (NAFLD) in laboratory mouse models of the disease. The study, published online June 30, found increased levels of an enzyme called cdk4 in patients with NAFLD and in mouse models. Using two drugs that inhibit cdk4 in mouse models reduced development of hepatic steatosis -- the first stage of the disease.

Contact: Nick Miller
nicholas.miller@cchmc.org
513-803-6035
Cincinnati Children's Hospital Medical Center

Public Release: 30-Jun-2016
Journal of the American College of Surgeons
Incidence of cancer in patients with large colorectal polyps lower than previously thought
For the majority of patients with large or difficult to remove colorectal polyps (growths in the colon), the incidence of cancer is actually lower than previously thought, and using more advanced endoscopic techniques that spare the colon may be a better, safer alternative to a traditional operation in certain cases, according to study results published online in the Journal of the American College of Surgeons in advance of print publication.

Contact: Sally Garneski
pressinquiry@facs.org
312-202-5409
American College of Surgeons

Public Release: 29-Jun-2016
Science Translational Medicine
Radiation-guided nanoparticles zero in on metastatic cancer
Zap a tumor with radiation to trigger expression of a molecule, then attack that molecule with a drug-loaded nanoparticle.

Contact: Science Press Package Team
scipak@aaas.org
202-326-6440
American Association for the Advancement of Science

Public Release: 29-Jun-2016
Neuro-Oncology
Breakthrough in brain cancer research made by Newcastle experts
Scientists at Newcastle University, UK, have made a pioneering breakthrough in the understanding of how a fatal brain tumour grows -- which could lead to improved treatments for patients.
Wellcome Trust, Engineering & Physical Sciences Research Council, Wellcome Trust Centre for Mitochondrial Research, Engineering & Physical Sciences Research Council's IDEAS Factory Sandpit, Faculty of Medical Sciences

Contact: Helen Rae
helen.rae@ncl.ac.uk
44-019-120-87374
Newcastle University

Public Release: 29-Jun-2016
Cell
Ovarian cancer study uncovers new biology
In what is believed to be the largest study of its kind, scientists at The Johns Hopkins University and the Pacific Northwest National Laboratory led a study that examined the proteomes of 169 ovarian cancer patients to identify critical proteins expressed by their tumors.
NIH/National Cancer Institute, US Department of Energy

Contact: Marisol Martinez
mmart150@jhmi.edu
410-464-6458
Johns Hopkins Medicine

Public Release: 29-Jun-2016
Cell
Ovarian cancer study provides painstaking look at inner workings of tumors
Scientists have examined the collections of proteins in the tumors of 169 ovarian cancer patients to identify critical proteins present in their tumors. The researchers say their achievement illustrates the power of combining genomic and proteomic data -- an approach known as proteogenomics -- to yield a more complete picture of the biology of a cancer that is the fifth leading cause of cancer deaths among women in the United States.
NIH/National Cancer Institute, National Institutes of Health

Contact: Tom Rickey
tom.rickey@pnnl.gov
509-375-3732
DOE/Pacific Northwest National Laboratory

Public Release: 29-Jun-2016
ESMO World Congress on Gastrointestinal Cancer 2016
Annals of Oncology
Anti-PD-L1 immunotherapy responsive in microsatellite-stable mCRC comb with MEK inhibition
Anti-PD-L1 immunotherapy may achieve a response in patients with microsatellite-stable metastatic colorectal cancer if combined with a MEK inhibitor, according to phase I data presented at the ESMO 18th World Congress of Gastrointestinal Cancer in Barcelona, Spain.

Contact: ESMO Press Office
media@esmo.org
European Society for Medical Oncology

Public Release: 29-Jun-2016
New England Journal of Medicine
Group of rare blood cancers respond to new treatment pioneered by Stanford physician
A global trial of an oral medication called midostaurin indicates that the drug can produce partial or complete resolution of organ damage in 60 percent of patients with a group of rare blood cancers known collectively as advanced systemic mastocytosis.

Contact: Krista Conger
kristac@stanford.edu
650-725-5371
Stanford University Medical Center

Public Release: 29-Jun-2016
Cancer Epidemiology, Biomarkers & Prevention
Persistent HPV infection raises risk of anal and genital cancers
Women with a history of severe cervical intraepithelial neoplasia, a precancerous condition of the cervix that arises from infection with the human papillomavirus (HPV), had a long-term increased risk of developing anal, vulvar, and vaginal cancer.
Danish Cancer Society Research Center

Contact: Lauren Riley
lauren.riley@aacr.org
215-446-7155
American Association for Cancer Research

Public Release: 29-Jun-2016
Cancer Research
New technique sorts drivers from passengers in cancer genomics, implicates GON4L
A University of Colorado Cancer Center study published in the journal Cancer Research demonstrates a novel method for sorting passenger from driver alterations, and uses this method to pinpoint a new driver and potential therapeutic target in cancer progression, GON4L.

Contact: Erika Matich
erika.matich@ucdenver.edu
University of Colorado Anschutz Medical Campus

Public Release: 29-Jun-2016
Oncotarget
Protein associated with improved survival in some breast cancer patients
A family of proteins that help cancer cells survive and spread around the body may be associated with improved prognosis for some women receiving treatment for breast cancer, research has shown.
Breast Cancer Now

Contact: Emma Thorne
emma.thorne@nottingham.ac.uk
44-011-595-15793
University of Nottingham

Public Release: 29-Jun-2016
BioTechniques
New method detects telomere length for research into cancer, aging
UT Southwestern Medical Center cell biologists have identified a new method for determining the length of telomeres, the endcaps of chromosomes, which can influence cancer progression and aging.

Contact: Lori Sundeen Soderbergh
lori.soderbergh@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center

Public Release: 29-Jun-2016
ACS Nano
How cancer cells spread and squeeze through tiny blood vessels (video)
The spread of cancer from a tumor's original location to other parts of the body can play a major role in whether the disease turns deadly. Many steps in this process, called metastasis, remain murky. But now scientists are gaining new insights into how cancer cells might squeeze through and even divide within narrow blood vessels while traveling in the body. They report their study using microtubular nanomembranes in the journal ACS Nano.

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society

Public Release: 29-Jun-2016
American Journal of Roentgenology
AJR opinion piece considers managing the radiation dose while communicating the risk
Despite evidence that low doses of ionizing radiation associated with imaging are not dangerous, the medical community is frequently faced with the challenge of communicating the risk and managing the dose.

Contact: Kimberly Coghill
kcoghill@arrs.org
703-858-4332
American Roentgen Ray Society

Public Release: 29-Jun-2016
Lancet Haematology
Everolimus R-CHOP combination safe for treating diffuse large B-cell lymphoma
The targeted therapy everolimus may be safely combined with R-CHOP for new, untreated diffuse large B-cell lymphoma according to the results of a pilot study by Mayo Clinic researchers published in the Lancet Haematology. R-CHOP is a combination of drugs used to treat lymphoma. The combination includes rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone.

Contact: Joe Dangor
newsbureau@mayo.edu
507-284-5005
Mayo Clinic

Public Release: 28-Jun-2016
Nature Communications
Researchers use liquid biopsy biomarkers to identify prostate cancer before surgery
Prostate cancer researchers have discovered biomarkers using non-invasive liquid biopsies to identify aggressive disease before surgery.
The Canadian Institutes of Health Research, National Institutes of Health, Ontario Institute for Cancer Research, Ontario Ministry of Health and Long-term Care, The Princess Margaret Cancer Foundation

Contact: Jane Finlayson
jane.finlayson@uhn.ca
416-946-2846
University Health Network

Public Release: 28-Jun-2016
International Journal of Cancer
Gene signature in ovarian cancer predicts survival and offers new drug target
A new UK study has identified a gene signature that predicts poor survival from ovarian cancer. The study also identified genes which help the cancer develop resistance to chemotherapy -- offering a new route to help tackle the disease.

Contact: Jenny Watkinson
j.watkinson2@bradford.ac.uk
127-423-6030
University of Bradford

Public Release: 28-Jun-2016
Nature Communications
Researchers find protein signatures for accurate noninvasive diagnosis of prostate cancer
Researchers at the Ontario Institute for Cancer Research and University Health Network in Toronto, along with researchers at the Eastern Virginia Medical School, have created protein signatures that accurately diagnose prostate cancer and can distinguish between patients with aggressive versus non-aggressive disease using a simple urine sample.

Contact: Christopher Needles
christopher.needles@oicr.on.ca
416-673-8505
Ontario Institute for Cancer Research

Public Release: 28-Jun-2016
Journal of Thoracic Oncology
Lung cancer experts seek public comments on revised molecular testing guideline
The College of American Pathologists, the International Association for the Study of Lung Cancer, and the Association for Molecular Pathology announced today the open comment period for the revised evidence-based guideline, 'Molecular Testing Guideline for Selection of Lung Cancer Patients for EGFR and ALK Tyrosine Kinase Inhibitors.'

Contact: Jeffrey Wolf
Jeff.Wolf@iaslc.org
720-325-2952
International Association for the Study of Lung Cancer

Public Release: 28-Jun-2016
Journal of Natural Products
Parsley and dill help fight cancer, research shows
A team of Russian scientists proposed an efficient approach to a novel agents with anticancer activity. A synthesis of these compounds is based on compounds extracted from parsley and dill seeds. The results of the study have been published in the Journal of Natural Products.

Contact: Matvey Kireev
matthew@phystech.edu
7-916-065-1016
Moscow Institute of Physics and Technology

Public Release: 28-Jun-2016
Cancer
Risk of death for adults with blood cancer higher in three N.C. regions
For patients treated in a hospital, the risk of death from acute myeloid leukemia was elevated in three regions of North Carolina compared to a benchmark.

Contact: Laura Oleniacz
laura_oleniacz@med.unc.du
919-445-4219
UNC Lineberger Comprehensive Cancer Center

Public Release: 28-Jun-2016
ACS Nano
A 2-in-1 punch for taking out cancer
Bioengineers at Brigham and Women's Hospital have engineered a single nanoparticle that comprises a synergistic drug pair and demonstrate that the mechanisms of resistance can be shut down to a degree that has never been achieved before.
US Department of Defense, National Institutes of Health, American Lung Association, Indo-US Joint Center, American Cancer Society

Contact: Haley Bridger
hbridger@partners.org
617-525-6383
Brigham and Women's Hospital

Public Release: 27-Jun-2016
Journal of Clinical Oncology
UTSA researcher develops new, non-invasive method to wipe out cancerous tumors
Matthew Gdovin, an associate professor in the UTSA Department of Biology, has developed a newly patented method to kill cancer cells. His discovery, described in a new study in The Journal of Clinical Oncology, may tremendously help people with inoperable or hard-to-reach tumors, as well as young children stricken with cancer.

Contact: Joanna Carver
joanna.carver@utsa.edu
210-243-4557
University of Texas at San Antonio

Public Release: 27-Jun-2016
Oncotarget
Bacterial colonies in human body linked to presence of cancer in mouth and throat
In a sample study, researchers at Johns Hopkins say they have found an association between the makeup of an individual's microbiome and head and neck cancer, a finding that potentially advances the quest for faster and more accurate cancer diagnosis and therapy.
NIH/National Cancer Institute, NIH/National Institute of Dental and Craniofacial Research

Contact: Vanessa McMains
vmcmain1@jhmi.edu
410-502-9410
Johns Hopkins Medicine

Showing releases 176-200 out of 1427.

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