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Showing releases 201-225 out of 1124.

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Public Release: 31-Oct-2012
Nature
1000 genomes study is 'guidebook' to how genes vary
A landmark project that has sequenced 1,092 human genomes from individuals around the world will help researchers to interpret the genetic changes in people with disease. The first study to break the '1000 genomes barrier' will enable scientists to begin to examine genetic variations at the scale of the populations of individual countries, as well as guiding them in their search for the rare genetic variations related to many diseases.
Wellcome Trust

Contact: University of Oxford Press Office
press.office@admin.ox.ac.uk
44-186-528-3877
University of Oxford

Public Release: 31-Oct-2012
American Society for Radiation Oncology 54th Annual Meeting
Stereotactic radiosurgery shows promise for kidney cancer
A first-of-its-kind clinical trial conducted at University Hospitals Case Medical Center Seidman Cancer Center has shown encouraging results for the use of stereotactic radiosurgery to treat kidney cancer. This non-invasive treatment technique may represent a potential new non-surgical option for patients with this deadly disease. Rod Ellis, MD presented results of a Phase 1 clinical trial in 20 patients with localized primary renal cancer at the Annual Meeting of the American Society for Radiation Oncology.

Contact: Alicia Reale
alicia.reale@uhhospitals.org
216-844-5158
University Hospitals Case Medical Center

Public Release: 31-Oct-2012
Nature
Unexpected factor contributes to melanoma risk in red-haired, fair-skinned individuals
The established elevated risk of melanoma among people with red hair and fair skin may be caused by more than just a lack of natural protection against ultraviolet radiation. In an article receiving Advance Online Publication in Nature, Massachusetts General Hospital researchers report finding that the type of skin pigment predominantly found in red-haired, fair-skinned individuals may itself contribute to the development of melanoma.
National Institutes of Health, Dr. Miriam and Sheldon G. Adelson Medical Research Foundation, US-Israel Binational Science Foundation, Melanoma Research Alliance

Contact: Katie Marquedant
kmarquedant@partners.org
617-726-0337
Massachusetts General Hospital

Public Release: 31-Oct-2012
Nature
Global genome effort seeks genetic roots of disease
By decoding the genomes of more than 1,000 people whose homelands stretch from Africa and Asia to Europe and the Americas, scientists have compiled the largest and most detailed catalog yet of human genetic variation. The massive resource will help medical researchers find the genetic roots of rare and common diseases in populations worldwide.
NIH/National Human Genome Research Institute

Contact: Caroline Arbanas
arbanasc@wustl.edu
314-286-0109
Washington University School of Medicine

Public Release: 31-Oct-2012
PLOS ONE
Health inequalities could be reduced by more effective health care, says new study
Health inequalities could be reduced by more effective healthcare, says new study.
National Institute for Health Research

Contact: Steve Levene
lsl7@le.ac.uk
44-011-629-58282
University of Leicester

Public Release: 31-Oct-2012
Proceedings of the National Academy of Sciences
Unlocking the secrets of DNA repair
Scientists from the University of Sheffield have unlocked one of the secrets to DNA repair -- helping doctors identify DNA base damage and a patient's susceptibility to certain types of cancer.

Contact: Amy Pullan
a.l.pullan@sheffield.ac.uk
01-142-229-859
University of Sheffield

Public Release: 31-Oct-2012
Open Biology
Team uses antisense technology that exploits gene splicing mechanism to kill cancer cells
The voracious growth of all cancers is powered by an alteration in cellular energy consumption. One characteristic of this is the production of a different version of the pyruvate kinase M gene, PK-M2, over the normal version, PK-M1. A CSHL team now shows they can specifically kill cancer cells using antisense oligonucleotides to modulate the splicing mechanism and stop production of PK-M2. The method shows promise as a possible universal cancer therapeutic strategy.
NIH/National Cancer Institute

Contact: Edward Brydon Ph.D.
ebrydon@cshl.edu
917-476-6633
Cold Spring Harbor Laboratory

Public Release: 31-Oct-2012
American Journal of Clinical Nutrition
Green tea found to reduce rate of some GI cancers
Women who drink green tea may lower their risk of developing some digestive system cancers, especially cancers of the stomach/esophagus and colorectum, according to a study led by researchers from Vanderbilt-Ingram Cancer Center.
NIH/National Cancer Institute

Contact: Dagny McMillin
dagny.mcmillin@vanderbilt.edu
615-322-4747
Vanderbilt University Medical Center

Public Release: 31-Oct-2012
PLOS ONE
Scientists unravel resistance to breast cancer treatment
Scientists have identified a molecular 'flag' in women with breast cancer who do not respond or have become resistant to the hormone drug tamoxifen.
Breakthrough Breast Cancer

Contact: Aeron Haworth
aeron.haworth@manchester.ac.uk
44-161-275-8383
University of Manchester

Public Release: 30-Oct-2012
Journal of National Cancer Institute
High levels of vitamin D in plasma protects against bladder cancer
High levels of vitamin D are associated with protection against bladder cancer, according to a multidisciplinary study coordinated by molecular biologists and epidemiologists from the Spanish National Cancer Research Centre, the conclusions of which are being published today in the Journal of the National Cancer Institute.

Contact: Nuria Noriega
nnoriega@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)

Public Release: 30-Oct-2012
Cancer Epidemiology, Biomarkers & Prevention
Some cancer survivors reported poor health-related quality of life years after diagnosis
Melanoma, breast and prostate cancer survivors reported quality of life similar to adults without cancer. Cervical, blood, colorectal and short-survival cancer survivors reported worse health compared to adults without cancer. The researchers estimated 3.3 million American cancer survivors have poor physical health.
NIH/National Cancer Institute

Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research

Public Release: 30-Oct-2012
Cancer Epidemiology, Biomarkers & Prevention
Many cancer survivors face health-related quality of life issues
Beating cancer is just the first step. More than one third of the 12.6 million cancer survivors in the United States have physical or mental problems that put their overall health in jeopardy, according to researchers at Wake Forest Baptist Medical Center.
NIH/National Cancer Institute

Contact: Marguerite Beck
marbeck@wakehealth.edu
336-716-2415
Wake Forest Baptist Medical Center

Public Release: 30-Oct-2012
Oncogene
Recent findings may help to fight melanoma's resistance to chemotherapy
Blocking the action of a particular protein in our skin could improve the treatment of skin cancers, according to a study published in Oncogene yesterday by Philippe Roux, a researcher at the University of Montreal's Institute for Research in Immunology and Cancer.
Canadian Cancer Society Research Institute, Cancer Research Society

Contact: William Raillant-Clark
w.raillant-clark@umontreal.ca
514-343-7593
University of Montreal

Public Release: 30-Oct-2012
American Society for Radiation Oncology 54th Annual Meeting
Penn researchers find error reporting improves perceptions of safety and may reduce incidents
Documenting adverse events improves perceptions of safety and may decrease incidents in multi-site clinical practices, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania. The results of the year-long study, which focused on the Radiation Oncology department's workflow, show a strong correlation between the implementation of a Conditions Reporting System and increasingly positive responses to staff surveys focusing on the culture of safety within the department.

Contact: Katie Delach
katie.delach@uphs.upenn.edu
215-349-5964
University of Pennsylvania School of Medicine

Public Release: 30-Oct-2012
American Society for Radiation Oncology 54th Annual Meeting
Delaying radiation therapy after hysterectomy ups risk of uterine cancer recurrence
Waiting too long after a hysterectomy to begin radiation therapy may increase the risk of uterine cancer recurrence, according to a new study from researchers at Henry Ford Hospital in Detroit. Results will be presented today at the 54th Annual Meeting of the American Society for Radiation Oncology in Boston.
Henry Ford Hospital

Contact: Krista Hopson
khopson1@hfhs.org
313-874-7207
Henry Ford Health System

Public Release: 30-Oct-2012
American Society for Radiation Oncology 54th Annual Meeting
ASTRO: Deviating from radiation protocols increases risk of treatment failure and death
Implementing measures to ensure radiation therapy protocols are followed not only decreases deviations, but it can also improve overall survival in cancer patients, Thomas Jefferson University Hospital researchers suggest in a first-of-its kind study presented during a plenary session at the American Society for Radiation Oncology 54th Annual Meeting in Boston.

Contact: Steve Graff
stephen.graff@jefferson.edu
215-955-5291
Thomas Jefferson University

Public Release: 29-Oct-2012
Socioeconomic disadvantage linked to breast cancer tumor disparity
ER- and PR-negative tumors were more common among black and Hispanic patients. Non-Hispanic black and Hispanic patients lived in more disadvantaged areas. Socioeconomic disadvantage accounted for half of the racial/ethnic disparity.

Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research

Public Release: 29-Oct-2012
Ethnic disparities in breast cancer survival remain despite socioeconomic similarities
Breast cancer survival is known to differ across racial/ethnic groups. More education, better neighborhood socioeconomic status improved survival rates.

Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research

Public Release: 29-Oct-2012
Cancer Discovery
Scientists decode 'software' instructions of aggressive leukemia cells
A team of national and international researchers, led by Weill Cornell Medical College scientists, have decoded the key "software" instructions that drive three of the most virulent forms of acute lymphoblastic leukemia (ALL). They discovered ALL's "software" is encoded with epigenetic marks, chemical modifications of DNA and surrounding proteins, allowing the research team to identify new potential biomarkers and therapeutic targets.
Chemotherapy Foundation, Burroughs Wellcome Foundation, Sackler Center

Contact: Lauren Woods
law2014@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College

Public Release: 29-Oct-2012
Participation in clinical trials high among gay, lesbian and bisexual cancer survivors
Association is not explained by other demographic differences. According to the researchers, their data should be interpreted cautiously.

Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research

Public Release: 29-Oct-2012
Nature Cell Biology
Prostate cancer prognosis hope
Scientists have discovered a molecular "tell" in laboratory experiments that could help doctors determine the severity of a patient's prostate cancer.
Cancer Research UK

Contact: Aeron Haworth
aeron.haworth@manchester.ac.uk
44-161-275-8383
University of Manchester

Public Release: 29-Oct-2012
Journal of Urology
For many prostate cancer patients, Web sites are too difficult to read
Ninety million American adults read below high school levels. But a study has found that only 4.8 percent of Web sites describing prostate cancer were written below a high school reading level. The median reading level was 12th grade.

Contact: Jim Ritter
jritter@lumc.edu
708-216-2445
Loyola University Health System

Public Release: 29-Oct-2012
ASTRO's 54th Annual Meeting
Radiation treatment after surgery improves survival for elderly women with early-stage breast cancer
Elderly women with early-stage breast cancer live longer with radiation therapy and surgery compared with surgery alone, researchers at the University of Maryland School of Medicine have found. The researchers, who collected data on almost 30,000 women, ages 70 to 84, with early, highly treatable breast cancer enrolled in a nationwide cancer registry, are reporting their findings at the 54th annual meeting of the American Society for Radiation Oncology.

Contact: Karen Warmkessel
kwarmkessel@umm.edu
41-032-889-194-104-04153
University of Maryland Medical Center

Public Release: 29-Oct-2012
Molecular Cell
New developments reveal a molecule with a promising function in terms of cancer treatment.
One of the current challenges in terms of cancer treatment is how it can be best adapted to patients: today the emphasis is on personalized treatment (factoring in genetic and metabolic profiles). In response to this growing need for personalization, there is an increasing demand for fundamental research to develop adapted future treatments.

Contact: Press
presse@inserm.fr
INSERM (Institut national de la santé et de la recherche médicale)

Public Release: 29-Oct-2012
Reducing radiation: Heart Institute model shows hope for new standards worldwide
The University of Ottawa Heart Institute is setting the stage in what could become a revolution in medical imaging in Canada as it announces striking results in radiation reduction for the diagnosis of cardiovascular disease.

Contact: Vincent Lamontagne
vlamontagne@ottawaheart.ca
613-899-6760
University of Ottawa Heart Institute

Showing releases 201-225 out of 1124.

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