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Showing releases 201-225 out of 1275.

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Public Release: 2-Mar-2015
Journal of Experimental Medicine
Promising new strategy to halt pancreatic cancer metastasis
Researchers have identified a novel treatment that could halt the spread of pancreatic cancer and prolong patient survival.
Academia Sinica, Ministry of Science and Technology Taiwan

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 2-Mar-2015
International Journal of Radiation Oncology • Biology • Physics
Improved survival for patients with brain mets who are 50 and younger and receive SRS alone
Cancer patients with limited brain metastases -- one to four tumors -- who are 50 years old and younger should receive stereotactic radiosurgery (SRS) without whole brain radiation therapy, according to a study available online, open-access, and published in the March 15, 2015 issue of the International Journal of Radiation Oncology * Biology * Physics.

Contact: Michelle Kirkwood
American Society for Radiation Oncology

Public Release: 2-Mar-2015
SIR 2015 Annual Scientific Meeting
3-D printing offers innovative method to deliver medication
3-D printing could become a powerful tool in customizing interventional radiology treatments to individual patient needs, with clinicians having the ability to construct devices to a specific size and shape. Researchers and engineers collaborated to print catheters, stents and filaments to deliver antibiotics and chemotherapeutic medications to a targeted area in cell cultures.

Contact: Ellen Acconcia
Society of Interventional Radiology

Public Release: 2-Mar-2015
FASEB Journal
Researchers identify the mitochondrial 'shield' that helps cancer cells survive
Scientists have moved closer to understanding why cancer cells can be so resilient, even when faced with the onslaught of nearly toxic drug cocktails, radiation, and even our own immune systems. A new research report appearing in the March 2015 issue of The FASEB Journal shows that intermediate filaments formed by a protein called 'vimentin' or VIF, effectively 'insulate' the mitochondria in cancer cells from any attempt to destroy the cell.

Contact: Cody Mooneyhan
Federation of American Societies for Experimental Biology

Public Release: 2-Mar-2015
Journal of Cell Biology
Sall4 is required for DNA repair in stem cells
A protein that helps embryonic stem cells retain their identity also promotes DNA repair. The findings raise the possibility that the protein, Sall4, performs a similar role in cancer cells, helping them survive chemotherapy.
Chinese Ministry of Science and Technology, California Institute for Regenerative Medicine

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 2-Mar-2015
Journal of Clinical Oncology
US women's awareness of breast density varies
Disparities in the level of awareness and knowledge of breast density exist among US women, according to the results of a Mayo Clinic study published in the Journal of Clinical Oncology.

Contact: Joe Dangor
Mayo Clinic

Public Release: 2-Mar-2015
Inorganic Chemistry
Preventing the spread of cancer with copper molecules
Chemists at Bielefeld University have developed a molecule containing copper that binds specifically with DNA and prevents the spread of cancer. First results show that it kills the cancer cells more quickly than cisplatin -- a widely used anti-cancer drug that is frequently administered in chemotherapy. When developing the anti-tumor agent, Dr. Thorsten Glaser and his team cooperated with biochemists and physicists. The design of the new agent is basic research.

Contact: Dr. Thorsten Glaser
Bielefeld University

Public Release: 2-Mar-2015
American Journal of Clinical Oncology
Use of new systemic adjuvant therapy in gastrointestinal tumors increasing
A new study finds that the use of adjuvant systemic therapy for localized gastrointestinal stromal tumors has significantly increased over time and that patients treated with the therapy have better survival than those treated with surgery alone.
American Cancer Society

Contact: David Sampson
American Cancer Society

Public Release: 2-Mar-2015
Nature Cell Biology
Researchers discover 'milk' protein that enables survival of the species
Australian researchers have discovered the protein MCL-1 is critical for keeping milk-producing cells alive and sustaining milk production in the breast. Without milk production, offspring cannot survive, making MCL-1 essential for survival of mammalian species.
National Health and Medical Research Council, Australian Cancer Research Foundation, National Breast Cancer Foundation, Cure Cancer Australia Foundation, Victorian Government

Contact: Liz Williams
Walter and Eliza Hall Institute

Public Release: 2-Mar-2015
Nature Genetics
Healthy-looking prostate cells mask cancer-causing mutations
Prostate cells that look normal under the microscope may be hiding genetic mutations that could develop into cancer, prompting new ways to improve treatment for the disease, according to research published in Nature Genetics.
Cancer Research UK, Wellcome Trust

Contact: Greg Jones
Cancer Research UK

Public Release: 1-Mar-2015
British Journal of General Practice
Black men less willing to be investigated for prostate cancer
To investigate the possible effects of patients' preferences and choices, a team led by the University of Exeter Medical School carried out a study in more than 500 men attending general practices.

Contact: Louise Vennells
University of Exeter

Public Release: 27-Feb-2015
Modern Pathology
New breast cancer test links immune 'hotspots' to better survival
Scientists have developed a new test which can predict the survival chances of women with breast cancer by analyzing images of 'hotspots' where there has been a fierce immune reaction to a tumor. Researchers used statistical software previously used in criminology studies of crime hotspots to track the extent to which the immune system was homing in and attacking breast cancer cells.
Engineering and Physical Sciences Research Council, The Institute of Cancer Research, London

Contact: Claire Hastings
Institute of Cancer Research

Public Release: 27-Feb-2015
Nature Protocols
New approach to assessing effectiveness of anti-cancer drugs
Manchester scientists have a developed a new method to monitor the effect of anti-cancer drugs on very rare leukaemia stem cells. The approach potentially allows doctors to screen patients and personalise their treatment.

Contact: Jamie Brown
University of Manchester

Public Release: 27-Feb-2015
Journal of Cell Biology
Breakthrough in understanding how cancer cells metastasize
A protein commonly found in human cells could be an important switch that activates cancer cell metastasis, according to a new study by researchers at the Montreal Neurological Institute and Hospital -- The Neuro at McGill University and the MUHC. The finding focuses attention on a biological mechanism that until now was largely overlooked. The discovery of the protein's effect significantly expands our understanding of epithelial cancers such as breast and lung cancer.

Contact: Anita Kar
McGill University

Public Release: 27-Feb-2015
Genitourinary Cancers Symposium
Mount Sinai researchers find chemotherapy after bladder cancer surgery improved survival
Patients that received chemotherapy after bladder cancer surgery demonstrated an approximately 30 percent lower risk of death than those that underwent surgery alone.

Contact: Lucia Lee
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 27-Feb-2015
Nature Reviews Clinical Oncology
Anderson Algorithm increases surgical success with advanced ovarian cancer
A surgical algorithm developed and implemented by ovarian cancer specialists at The University of Texas MD Anderson Cancer Center dramatically increases the frequency of complete removal of all visible tumor -- a milestone strongly tied to improved survival.

Contact: Scott Merville
University of Texas M. D. Anderson Cancer Center

Public Release: 27-Feb-2015
JAMA Oncology
Researchers detail reasons for ibrutinib therapy discontinuation in CLL
About 10 percent of patients with chronic lymphocytic leukemia discontinued therapy with the Bruton tyrosine kinase inhibitor drug ibrutinib because of disease progression during clinical trials, according to a study published online in JAMA Oncology by scientists at The Ohio State University Comprehensive Cancer Center Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

Contact: Amanda J. Harper
Ohio State University Wexner Medical Center

Public Release: 26-Feb-2015
British Journal of Cancer
Urine test could lead to better treatment of bladder cancer
Researchers at the University of Birmingham believe that a simple urine test could help to guide clinicians in the treatment of bladder cancer patients.
Cancer Research UK, University of Birmingham, Birmingham/Black Country/West Midlands North and South Comprehensive Local Research Networks, University of Birmingham

Contact: Luke Harrison
University of Birmingham

Public Release: 26-Feb-2015
IU researchers identify pancreatic cancer patients who benefit from personalized treatment
Cancer researchers at Indiana University report that about 15 percent of people with pancreatic cancer may benefit from therapy targeting a newly identified gene signature.
NIH/National Cancer Institute

Contact: Michael Schug
Indiana University

Public Release: 26-Feb-2015
American Journal of Roentgenology
Ultrasound lags behind MRI for supplemental breast cancer screening
Although supplemental screening via ultrasound is unaffected by breast density, is not associated with ionizing radiation, and does not require IV contrast material, acceptance of this modality has lagged.

Contact: Lissa D. Hurwitz
American Roentgen Ray Society

Public Release: 26-Feb-2015
New England Surgical Society 95th Annual Meeting
Journal of American College of Surgeons
Chemo before breast cancer operation increases likelihood of breast-preserving procedure
Patients with larger malignant tumors of the breast who undergo chemotherapy before a breast cancer operation are more likely to opt for a breast-preserving procedure and forgo a mastectomy (surgical removal of the breast), according to a new study published online as an 'article in press' in the Journal of the American College of Surgeons. The study will appear in a print edition of the Journal this spring.

Contact: Sally Garneski
American College of Surgeons

Public Release: 26-Feb-2015
Journal of Thoracic Oncology
Online education tool helps bridge gaps in therapeutic decision-making for advanced NSCLC
A new interactive online tool helps educate practicing oncologists worldwide with therapeutic decision-making for advanced non-small cell lung cancer based on a patient's molecular and clinical characteristics by providing feedback from an expert panel.

Contact: Murry Wynes
International Association for the Study of Lung Cancer

Public Release: 26-Feb-2015
BMC Medicine
The numbers are in: 1.8 millions Australian smokers likely to die from their habit
The first large-scale, direct evidence on smoking and mortality in Australia shows up to 1.8 million of our 2.7 million smokers are likely to die from their habit if they continue to smoke, losing on average 10 years of life expectancy.

Contact: Anne Rahilly
University of Melbourne

Public Release: 26-Feb-2015
Cancer screening concerns
Adults with intellectual and developmental disabilities are much less likely to be screened for colorectal cancer, research shows.

Contact: Rosie Hales
613-533-6000 x77513
Queen's University

Public Release: 26-Feb-2015
Journal of Biological Chemistry
Moffitt researchers identify protein pathway involved in brain tumor stem cell growth
Glioblastomas are a highly aggressive type of brain tumor, with few effective treatment options. Moffitt Cancer Center researchers are one step closer to understanding glioblastoma development following the identification of a key protein signaling pathway involved in brain tumor stem cell growth and survival. Brain tumor stem cells are believed to play an important role in glioblastoma development and may be possible therapeutic targets.
The V Foundation for Cancer Research, Moffitt Cancer Center Foundation.

Contact: Kim Polacek
H. Lee Moffitt Cancer Center & Research Institute

Showing releases 201-225 out of 1275.

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