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Showing releases 201-225 out of 1290.

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Public Release: 23-Mar-2015
Nature Medicine
Combination therapy boosts antiviral response to chronic infection
A Yale-led team has identified a promising new combination immunotherapy to enhance the body's ability to fight chronic viral infections and possibly cancer.
Yale Medical Scientist Training Program, and Howard Hughes Medical Institute

Contact: Ziba Kashef
Yale University

Public Release: 23-Mar-2015
Journal of Clinical Oncology
Detecting cancer cells in blood can give an early warning of treatment failure
A blood test that measures the number of cells shed from prostate tumors into the bloodstream can act as an early warning sign that treatment is not working, a major new study shows. Researchers showed that measuring the numbers of circulating tumor cells in the blood predicted which men were benefiting least from a prostate cancer drug after as little as 12 weeks of treatment.
Medical Research Council, Janssen Diagnostics, Prostate Cancer Foundation, Prostate Cancer UK

Contact: Claire Hastings
Institute of Cancer Research

Public Release: 23-Mar-2015
Stress management techniques improve long-term mood and quality of life
A new study shows that providing women with skills to manage stress early in their breast cancer treatment can improve their mood and quality of life many years later.

Contact: Evelyn Martinez

Public Release: 23-Mar-2015
Cancer Prevention Research
Metformin and vitamin D3 show impressive promise in preventing colorectal cancer
The concept was simple: if two compounds each individually show promise in preventing colon cancer, surely it's worth trying the two together to see if even greater impact is possible. Not only did the combination of the two improve outcomes in animal studies, but the dual-compound effect was dramatically better than either option alone. Their findings served as the cover feature February's edition of Cancer Prevention Research.
NIH/National Cancer Institute

Contact: Jeannette Spalding
Case Western Reserve University

Public Release: 23-Mar-2015
American Chemical Society 249th National Meeting & Exposition
Popular artificial sweetener could lead to new treatments for aggressive cancers
Saccharin, the artificial sweetener that is the main ingredient in Sweet 'N Low, Sweet Twin and Necta, could do far more than just keep our waistlines trim. This popular sugar substitute could potentially lead to the development of drugs capable of combating aggressive, difficult-to-treat cancers with fewer side effects. They will present their work today at the 249th National Meeting & Exposition of the American Chemical Society.

Contact: Michael Bernstein
American Chemical Society

Public Release: 23-Mar-2015
BMC Medicine
Good news for serial cereal eaters
A diet high in whole grains and cereal fibers is associated with a reduced risk of premature death, according to research published in the open-access journal BMC Medicine. The results also show cereal fibers to be associated with reduced risk of deaths in varying degrees for chronic diseases including cancer, heart disease, respiratory disease and diabetes.

Contact: Shane Canning
BioMed Central

Public Release: 23-Mar-2015
International Journal of Radiation Oncology, Biology and Physics
Sweeping prostate cancer review upends widely held belief on radiation after surgery
Two new studies have upended the widely held view that it's best to delay radiation treatment as long as possible after the removal of the prostate in order to prevent unwanted side effects.
Prostate Cancer Foundation

Contact: Josh Barney
University of Virginia Health System

Public Release: 23-Mar-2015
Journal of Cell Biology
Stress granules ease the way for cancer metastasis
Tumors that produce more stress granules are more likely to metastasize, according to researchers in Canada. The results suggest that drugs to inhibit the formation of these structures might rein in cancer metastasis.
Terry Fox Research Institute, Prostate Cancer Canada-Movember Foundation, German Research Foundation, British Columbia Cancer Foundation

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 23-Mar-2015
American Journal of Managed Care
Implementing decision aids affects care decisions in urology
After Group Health Cooperative implemented video-based decision aids for men with two common prostate conditions, rates of elective surgery for benign prostatic hyperplasia and rates of active treatment for localized prostate cancer declined over six months. But the total cost of health care for those patients did not fall significantly.
Commonwealth Fund, Informed Medical Decisions Foundation, Group Health Foundation, Health Dialog

Contact: Rebecca Hughes
Group Health Research Institute

Public Release: 23-Mar-2015
TSRI team discovers enzyme that keeps blood stem cells functional to prevent anemia
When stem cells become too active and divide too often, they risk acquiring cell damage and mutations. In the case of blood stem cells (also called HSCs), this can lead to blood cancers, a loss of blood cells and an impaired ability to fight disease. Scientists at The Scripps Research Institute have found that a particular enzyme in HSCs is key to maintaining healthy periods of inactivity.
National Institutes of Health, Leukemia and Lymphoma Society, California Institute for Regenerative Medicine, Deutsche Forschungsgemeinschaft

Contact: Madeline McCurry-Schmidt
Scripps Research Institute

Public Release: 23-Mar-2015
Journal of Clinical Investigation
Combining the old and new to kill cancer cells
A team of Singapore based scientists have found that pairing a new approach with an old drug may be an effective approach to treat common cancers. In a landmark study, professor David Virshup and Dr. Jit Kong Cheong, from Duke-NUS Graduate Medical School Singapore, identified a new signalling pathway that regulates the internal diet of cancers.
Singapore Ministry of Health's National Medical Research Council

Contact: Dharshini Subbiah
Duke-NUS Graduate Medical School Singapore

Public Release: 23-Mar-2015
Journal of Sexual Medicine
Exercise linked to improved erectile and sexual function in men
Men who exercise more have better erectile and sexual function, regardless of race, according to a recent study published in the Journal of Sexual Medicine. While past studies have highlighted the relationship between better erectile function and exercise, African-American men have been underrepresented in this literature.

Contact: Cara Martinez
Cedars-Sinai Medical Center

Public Release: 23-Mar-2015
Journal of Clinical Investigation
Metabolic compensation underlies drug resistance in glioblastoma
A new study in the Journal of Clinical Investigation indicates that mTOR inhibitor resistance in gliobalstoma is likely the result of compensatory glutamine metabolism.
Takeda Science Foundation, Ludwig Institute for Cancer Research, NIH/National Institute for Neurological Diseases and Stroke, NIH/National Cancer Institute, Ben and Catherine Ivy Foundation, Defeat GBM Research Collaboration

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 23-Mar-2015
Journal of Clinical Oncology
How to get smarter on pills for seniors
Cancer patients over the age of 65 often take multiple drugs, which can interfere with cancer treatment. A new study shows that currently used tools to prevent over-medicating senior cancer patients need improvement.

Contact: Edyta Zielinska
Thomas Jefferson University

Public Release: 23-Mar-2015
Stress management techniques improve long-term mood and quality of life
A new study shows that providing women with skills to manage stress early in their breast cancer treatment can improve their mood and quality of life many years later.

Contact: Megan Ondrizek
University of Miami

Public Release: 22-Mar-2015
American Chemical Society 249th National Meeting & Exposition
Vitamin D may keep low-grade prostate cancer from becoming aggressive
Taking vitamin D supplements could slow or even reverse the progression of less aggressive, or low-grade, prostate tumors without the need for surgery or radiation, a scientist will report today at the 249th National Meeting & Exposition of the American Chemical Society.

Contact: Michael Bernstein
American Chemical Society

Public Release: 22-Mar-2015
New potential for personalized treatments in bowel cancer
Scientists have found that genetic changes in bowel tumors are linked to the way the body's immune system responds to the cancer.
Cancer Research UK

Contact: Stephanie McClellan
Cancer Research UK

Public Release: 20-Mar-2015
Nature Communications
Stinging nettle chemical improves cancer drug
A cancer drug could be made 50 times more effective by a chemical found in stinging nettles and ants, new research finds. Researchers at the University of Warwick found that when the chemical, Sodium Formate, is used in combination with a metal-based cancer treatment it can greatly increase its ability to shut down cancer cells.
European Research Council, Engineering and Physical Sciences Research Council, University of Warwick IAS, Science City

Contact: Tom Frew
University of Warwick

Public Release: 20-Mar-2015
Lancet Oncology
Measuring treatment response proves to be a powerful tool for guiding leukemia treatment
Measuring the concentration of leukemia cells in patient bone marrow during the first 46 days of chemotherapy should help boost survival of young leukemia patients by better matching patients with the right intensity of chemotherapy. St. Jude Children's Research Hospital investigators led the research, which appears in the March 20 edition of the journal Lancet Oncology.
National Institutes of Health, ALSAC

Contact: Summer Freeman
St. Jude Children's Research Hospital

Public Release: 20-Mar-2015
American Journal of Pathology
Researchers ID potential prognostic marker for recurrence of head and neck squamous cell carcinoma
A new study provides the first evidence that the mediator complex subunit 15 (MED15) may play a crucial role in the pathophysiology of head and neck squamous cell carcinoma (HNSCC). MED15 overexpression was found to be associated with higher mortality rates in HNSCC patients with cancer recurrence, particularly in oral cavity/oropharyngeal tumors, according to the study published in the American Journal of Pathology. MED15 overexpression was also associated with heavy alcohol consumption, which is an HNSCC risk factor.
German Research Foundation, Rudolf-Becker-Foundation, Medical Faculty of the University of Bonn, Gerok-Fellowship, and others

Contact: Eileen Leahy
Elsevier Health Sciences

Public Release: 19-Mar-2015
British Journal of Cancer
Text message reminders boost breast cancer screening attendance
Women who received a text message reminding them about their breast cancer screening appointment were 20 percent more likely to attend than those who were not texted, according to a study published in the British Journal of Cancer today.

Contact: Emily Head
Cancer Research UK

Public Release: 19-Mar-2015
Strengthening the immune system's fight against brain cancer
When cancer strikes, it may be possible for patients to fight back with their own defenses, using a strategy known as immunotherapy. According to a new study published in Nature, researchers have found a way to enhance the effects of this therapeutic approach in glioblastoma, a deadly type of brain cancer, and possibly improve patient outcomes. The research was funded by the National Institutes of Health.
NIH/National Institute of Neurological Disorders and Stroke, NIH/National Cancer Institute

Contact: Barbara McMakin
NIH/National Institute of Neurological Disorders and Stroke

Public Release: 19-Mar-2015
Molecular Cancer Therapeutics
Bright new hope for beating deadly hereditary stomach and breast cancers
Deadly familial stomach and lobular breast cancers could be successfully treated at their earliest stages, or even prevented, by existing drugs that have been newly identified by cancer genetics researchers at New Zealand's University of Otago.
Health Research Council of New Zealand

Contact: Parry Guilford
University of Otago

Public Release: 19-Mar-2015
Physician Leadership Journal
Streamlined 'military' work flow means more patient appointments and fewer return visits
Both patients and physicians may benefit from a 'work flow' system developed at military medical facilities and tested at a Johns Hopkins Kimmel Cancer Center clinic, according to results of an efficiency study.

Contact: Vanessa Wasta
Johns Hopkins Medicine

Public Release: 19-Mar-2015
Nature Communications
Scientists trace genomic evolution of high-risk leukemia
By genomic sequencing of leukemia cells from relapsed patients at different stages, scientists have discovered key details of how acute lymphoblastic leukemia cells mutate to survive chemotherapy.
Pediatric Cancer Genome Project, NIH/National Cancer Institute, St. Baldrick's Foundation, ALSAC

Contact: Summer Freeman
St. Jude Children's Research Hospital

Showing releases 201-225 out of 1290.

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