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Showing releases 201-225 out of 1216.

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Public Release: 1-Jul-2013
Journal of Clinical Investigation
How the body aids and abets the spread of cancer
The very system that is meant to protect the body from invasion may be a traitor. These new findings of a study, led by investigators at the Research Institute of the McGill University Health Centre reveal that infection-fighting white blood cells play a role in activating cancer cells and facilitating their spread to secondary tumours. This research, published today in the Journal of Clinical Investigation has significant implications for both the diagnosis and treatment of cancer.
Canadian Cancer Society Research Institute

Contact: Julie Robert
julie.robert@muhc.mcgill.ca
514-934-1934 x71381
McGill University Health Centre

Public Release: 1-Jul-2013
Journal of Clinical Investigation
JCI early table of contents for July 1, 2013
This release contains summaries, links to PDFs, and contact information for the following newsworthy releases to be published online, July 1, 2013, in the JCI: Potential gene therapy for Sickle cell disease; Cross-species malaria immunity induced by chemically attenuated parasites; A potential gene therapy for Mucopoylsaccharidosis Type IIIA; and many more.

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 1-Jul-2013
The Preventing Overdiagnosis conference on September 10-12, 2013
Thyroid
Thyroid cancer -- rising most rapidly among insured patients
The rapid increase in papillary thyroid cancer may not be linked to increase in occurrence, instead it may be linked to an increase in the diagnosis of pre-cancerous conditions and to a person's insurance status, according to a paper published in Thyroid, which included the research of Louise Davies, M.D., M.S., Geisel School of Medicine at Dartmouth, and assistant professor of Surgery of The Dartmouth Institute.

Contact: Donna Dubuc
Donna.M.Dubuc@Dartmouth.edu
603-653-3615
Dartmouth-Hitchcock Medical Center

Public Release: 1-Jul-2013
Cell Reports
Researchers have discovered a new proteasome regulatory mechanism
Dysfunction of the ubiquitin-proteasome system has been detected in many neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases and certain types of cancer. Researchers at the University of Helsinki, Finland, have now discovered an important mechanism that regulates proteasome activity.

Contact: Dr. Carina Holmberg-Still
carina.holmberg@helsinki.fi
358-503-554-364
University of Helsinki

Public Release: 1-Jul-2013
Annals of Internal Medicine
Annals of Internal Medicine tip sheet for July 2, 2013
Below is information about articles being published in the July 2 issue of Annals of Internal Medicine. The information is not intended to substitute for the full article as a source of information. Annals of Internal Medicine attribution is required for all coverage.

Contact: Megan Hanks
mhanks@acponline.org
215-351-2656
American College of Physicians

Public Release: 1-Jul-2013
Journal of Leukocyte Biology
Too much of a good thing? Too many 'healing' cells delays wound healing
New research in the Journal of Leukocyte Biology, shows that wound healing can be delayed because the body produces too many mast cells, which promote healing. Overabundance of these cells causes the overproduction of IL-10, preventing certain white blood cells from reaching the wound. The work may provide better treatments for the elderly with lower extremity skin ulcers, women with upper-extremity wounds following breast cancer surgery, and delayed healing in all skin wounds.

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology

Public Release: 1-Jul-2013
Clinical Cancer Research
UNC murine study predicts cancer drug responsiveness in human tumors
A University of North Carolina School of Medicine research team found that genetically engineered mouse models were able to accurately predict human response to a standard chemotherapy drug combination commonly used in the clinic.
NIH/National Cancer Institute, Breast Cancer Research Foundation, and others

Contact: Dianne Shaw
dgs@med.unc.edu
919-966-7834
University of North Carolina Health Care

Public Release: 1-Jul-2013
Proceedings of the National Academy of Sciences
Neuroblastoma: Autophagy protects from chemotherapy
Cells can digest parts of themselves in a process called autophagy. This is a survival strategy that helps them overcome starvation and other conditions of depletion. In therapy-resistant cases of neuroblastoma, scientists from the German Cancer Research Center and Heidelberg University Hospital have now discovered an enzyme which promotes autophagy and thus protects cancer cells from treatment through chemotherapy. Blocking this enzyme might make cancer cells more sensitive to treatment.

Contact: Dr. Sibylle Kohlstädt
s.kohlstaedt@dkfz.de
Helmholtz Association of German Research Centres

Public Release: 1-Jul-2013
Molecular Cell
Breakthrough discovery into the regulation of a key cancer drug target
University of Leicester-led research offers new insights into how the genome is regulated by signalling molecules within human cells.
Wellcome Trust

Contact: John Schwabe
js336@leicester.ac.uk
44-011-622-97030
University of Leicester

Public Release: 30-Jun-2013
Bulletin of the World Health Organization
Tobacco control policies stop people from smoking and save lives
Tobacco control measures put in place in 41 countries between 2007 and 2010 will prevent some 7.4 million premature deaths by 2050, according to a study published in the Bulletin of the World Health Organization.

Contact: Karen Mallet
km463@georgetown.edu
Georgetown University Medical Center

Public Release: 28-Jun-2013
Stem Cells
Study links cardiac hormone-related inflammatory pathway with tumor growth
A cardiac hormone signaling receptor abundantly expressed both in inflamed tissues and cancers appears to recruit stem cells that form the blood vessels needed to feed tumor growth, reports a new study by scientists at the University of South Florida Nanomedicine Research Center.
National Institutes of Health, Florida Biomedical Research Grant

Contact: Anne DeLotto Baier
abaier@health.usf.edu
813-974-3303
University of South Florida (USF Health)

Public Release: 28-Jun-2013
Journal of National Cancer Institute
Biomarker predicts risk of breast cancer recurrence after tamoxifen treatment
A biomarker reflecting expression levels of two genes in tumor tissue may be able to predict which women treated for estrogen-receptor-positive breast cancer should receive a second estrogen-blocking medication after completing tamoxifen treatment.
National Institutes of Health, US Department of Defense/Breast Cancer Research Program, Avon Foundation, Breast Cancer Foundation, Novartis

Contact: Katie Marquedant
kmarquedant@partners.org
617-726-0337
Massachusetts General Hospital

Public Release: 27-Jun-2013
Frontiers
Frontiers news briefs: 27 June
In this week's news briefs: The benefits of endophytic bacteria; clustering the lexicon in the brain; and how oncogenes and tumor suppressor genes can contribute to chromosomal instability.

Contact: Gozde Zorlu
gozde.zorlu@frontiersin.org
Frontiers

Public Release: 27-Jun-2013
Journal of Health Communication
How to boost Hispanics' participation in clinical trials? Relate to them, Moffitt study shows
Hispanic cancer patients rarely participate in clinical trials, but researchers want to tailor a Spanish DVD to help change this. To create a relevant educational tool, Moffitt Cancer Center researchers investigated why awareness of and participation in trials are so low in this population.

Contact: Kim Polacek
kim.polacek@moffitt.org
813-745-7408
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 27-Jun-2013
Cell Reports
Research in fruit flies provides new insight into Barrett's esophagus
Research focused on the regulation of the adult stem cells that line the gastrointestinal tract of Drosophila suggests new models for the study of Barrett's esophagus. Barrett's esophagus is a condition in which the cells of the lower esophagus transform into stomach-like cells. In most cases this transformation has been thought to occur directly from chronic acid indigestion. A new study suggests a different cause, namely a change in stem cell function, for this transformation.
National Institutes of Health, Ellison Medical Foundation

Contact: Kris Rebillot
krebillot@buckinstitute.org
415-209-2080
Buck Institute for Age Research

Public Release: 27-Jun-2013
Molecular and Cellular Biology
Telomere length influences cancer cell differentiation
Researchers from the Japanese Foundation for Cancer Research in Tokyo have discovered that forced elongation of telomeres (extensions on the end of chromosomes) promotes the differentiation of cancer cells, probably reducing malignancy, which is strongly associated with a loss of cell differentiation. They report their findings in a manuscript published online ahead of print, in the journal Molecular and Cellular Biology.

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology

Public Release: 27-Jun-2013
Journal of the American College of Surgeons
Surgeons report melanoma recurs after 10 years in more than 6 percent of patients
Recurrence of melanoma skin cancer 10 or more years after initial treatment is more common than previously thought, occurring in more than one in 20 patients. However, according to a new study, these patients tend to live longer after their cancer returns than patients whose melanoma recurs in the first three years. The study results appear in the July issue of the Journal of the American College of Surgeons.
NIH/National Cancer Institute, Melanoma Research Alliance, and others

Contact: Dan Hamilton
pressinquiry@facs.org
312-202-5328
American College of Surgeons

Public Release: 27-Jun-2013
PLOS ONE
Protein is involved with colon cancer cell's ability to invade other cells
Understanding how the protein km23-1 enables in the spread of colon cancer may lead to new treatments for the disease, according to researchers at Penn State College of Medicine.
National Institutes of Health, Pennsylvania Department of Health

Contact: Matthew Solovey
msolovey@hmc.psu.edu
717-531-8606
Penn State

Public Release: 27-Jun-2013
International Journal of Hyperthermia
After Great Dane success, cancer doc eyes brain tumors
Two papers in the International Journal of Hyperthermia tell CU Cancer Center investigator's success story with his 12 year old Great Dane, Star, and set the stage for a trial in human glioblastoma of the vaccine that led to Star's dramatic and prolonged improvement.

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 26-Jun-2013
Journal of Cell Science
University of East Anglia scientists make major advances important for cancer research
Scientists at the University of East Anglia have made a major advancement in understanding tissue development that has important implications for cancer. Findings published today in the journal Cell Science show how the protein EB2 is a key regulator of tube-like structures inside cells and critical for normal tissue development and function. The findings are an important step in the race to find cures for cancers including gut, breast and pancreatic cancer.
Biotechnology and Biosciences Research Council, Big C

Contact: Lisa Horton
l.horton@uea.ac.uk
44-016-035-92764
University of East Anglia

Public Release: 26-Jun-2013
Nature Scientific Reports
Virtual skin model reveals secrets of skin aging
We constantly grow new skin and slough off the old. Until now, scientists have never agreed on exactly how this works, but new research from the University of Sheffield may provide the answer.
University of Sheffield, Procter & Gamble Company

Contact: Dayna Hochstein
dhochstein@spectrumscience.com
202-955-6222
Spectrum

Public Release: 26-Jun-2013
Cancer Research
A circuitous route to therapy resistance
Scientists from the German Cancer Research Center and Heidelberg University Hospital have discovered a cause of resistance to therapy in cases of brain cancer. Microglia cells migrate into tumors and supply cancer cells with a substance needed for the repair of DNA damage. The cells thus escape programmed cell death (apoptosis). Blocking this resistance mechanism might lead to more effective treatments for malignant brain cancer.

Contact: Dr. Sibylle Kohlstädt
s.kohlstaedt@dkfz.de
Helmholtz Association of German Research Centres

Public Release: 25-Jun-2013
Journal of Clinical Oncology
'Active surveillance' may miss aggressive prostate cancers in black men
A Johns Hopkins study of more than 1,800 men ages 52 to 62 suggests that African-Americans diagnosed with very-low-risk prostate cancers are much more likely than white men to actually have aggressive disease that goes unrecognized with current diagnostic approaches.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, and others

Contact: John Lazarou
jlazaro1@jhmi.edu
410-502-8902
Johns Hopkins Medicine

Public Release: 25-Jun-2013
Cancer Research
Human and canine lymphomas share molecular similarities, first large-scale comparison shows
A team of scientists from the University of North Carolina School of Medicine, North Carolina State University's College of Veterinary Medicine and Duke University have conducted one of the first studies to directly compare canine and human B-cell lymphoma by examining molecular similarities and differences between the two species.
University Cancer Research Fund, University of North Carolina

Contact: Dianne Shaw
dgs@med.unc.edu
919-966-7834
University of North Carolina Health Care

Public Release: 25-Jun-2013
Oncogene
USC research IDs potential treatment for deadly, HIV-related blood cancer
Researchers at the USC Norris Comprehensive Cancer Center have discovered a promising new way to treat a rare and aggressive blood cancer most commonly found in people infected with HIV.
National Institutes of Health, STOP Cancer Foundation

Contact: Alison Trinidad
alison.trinidad@usc.edu
323-442-3941
University of Southern California - Health Sciences

Showing releases 201-225 out of 1216.

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