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Showing releases 201-225 out of 1244.

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Public Release: 27-Jul-2014
Nature
New drug target can break down cancer's barrier against treatment
Scientists have found that a molecule -- focal adhesion kinase -- signals the body to repair itself after chemotherapy or radiotherapy, which kill cancer cells by damaging DNA.
Cancer Research UK

Contact: Greg Jones
greg.jones@cancer.org.uk
44-203-469-8311
Cancer Research UK

Public Release: 25-Jul-2014
Cancer Research
Exposure to dim light at night may make breast cancers resistant to tamoxifen
For rats bearing human breast tumors, exposure to dim light at night made the tumors resistant to the breast cancer drug tamoxifen, according to data published in Cancer Research, a journal of the American Association for Cancer Research. The negative effects of dim light exposure on tamoxifen treatment were overcome by giving rats a melatonin supplement during the night.
National Institutes of Health, American Association for Laboratory Animal Science

Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research

Public Release: 25-Jul-2014
Cancer
Informed consent: False positives not a worry in lung cancer study
A new study of participants in the National Lung Screening Trial finds that a false positive screen result -- a screening test in which initial findings of concern for cancer are later found not to be worrisome -- did not cause participants undue anxiety or reduced quality of life. Researchers hypothesize that clear and accurate consent forms prepared patients for these false positive diagnoses.
National Cancer Institute

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University

Public Release: 25-Jul-2014
Journal of Clinical Investigation
Study shows epigenetic changes can drive cancer
Researchers at the United States Department of Agriculture/Agricultural Research Service Children's Nutrition Research Center at Baylor College of Medicine and Texas Children's Hospital have now created a mouse model providing the first in vivo evidence that epigenetic alterations alone can cause cancer. Their report appears today in the Journal of Clinical Investigation.
Sidney Kimmel Foundation, US Department of Agriculture, March of Dimes, NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Dipali Pathak
pathak@bcm.edu
713-798-4710
Baylor College of Medicine

Public Release: 25-Jul-2014
Cancer Research
Total darkness at night is key to success of breast cancer therapy -- Tulane study
Exposure to light at night, which shuts off nighttime production of the hormone melatonin, renders breast cancer completely resistant to tamoxifen, a widely used breast cancer drug, says a new study by Tulane University School of Medicine cancer researchers.
National Institutes of Health, American Association for Laboratory Animal Science, Edmond and Lily Safra Endowed Chair for Breast Cancer Research at Tulane Cancer Center

Contact: Arthur Nead
anead@tulane.edu
504-247-1443
Tulane University

Public Release: 25-Jul-2014
2014 Patient and Family Conference
Brain tumor causes and risk factors elude scientists
Today, nearly 700,000 people in the US are living with a brain tumor, and yet, when it comes to pinpointing causes or risk factors, scientists are still searching for answers.

Contact: Kate Butler
kbutler@abta.org
773-577-8792
Case Western Reserve University

Public Release: 25-Jul-2014
Annals of Oncology
Is Europe putting cancer research at risk?
The European Society for Medical Oncology has expressed concern that the proposed EU General Data Protection Regulation could make cancer research impossible and add a significant burden to both doctors and cancer patients.

Contact: ESMO Press Office
media@esmo.org
European Society for Medical Oncology

Public Release: 25-Jul-2014
International Journal of Cancer
Clearing cells to prevent cervical cancer
A study published online in the International Journal of Cancer earlier this month describes a novel approach to preventing cervical cancer based on findings showing successful reduction in the risk of cervical cancer after removal of a discrete population of cells in the cervix.

Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-534-6383
Brigham and Women's Hospital

Public Release: 25-Jul-2014
Cancer
ACR statement on cancer study regarding patient anxiety from CT lung cancer screening
Anxiety regarding inconclusive cancer screening test results among some patients is real and is only natural. However, as evidenced by Gareen et al., published July 25 in Cancer, the incidence and effects of anxiety associated with false positive or other results of computed tomography lung cancer screening exams are far less than claimed by some in the medical community.

Contact: Shawn Farley
PR@acr.org
703-648-8936
American College of Radiology

Public Release: 25-Jul-2014
WIREs Nanomedicine and Nanobiotechnology
Scientists test nanoparticle 'alarm clock' to awaken immune systems put to sleep by cancer
Researchers explore ways to wake up the immune system with nanoparticles so it recognizes and attacks invading cancer cells.

Contact: Donna Dubuc
Donna.M.Dubuc@Dartmouth.edu
603-653-3615
The Geisel School of Medicine at Dartmouth

Public Release: 25-Jul-2014
Annals of Surgery
Test increases odds of correct surgery for thyroid cancer patients
The routine use of a molecular testing panel increases the likelihood of performing the correct initial surgery for thyroid cancer patients by 30 percent, the University of Pittsburgh Cancer Institute, partner with University of Pittsburgh Medical Center CancerCenter, reports in the Annals of Surgery. The test is available at the University of Pittsburgh Medical Center/University of Pittsburgh Cancer Institute Multidisciplinary Thyroid Center and other diagnostic testing agencies.
University of Pittsburgh Medical Center

Contact: Allison Hydzik
hydzikam@upmc.edu
412-647-9975
University of Pittsburgh Schools of the Health Sciences

Public Release: 24-Jul-2014
PLOS ONE
Researchers discover new way to determine cancer risk of chemicals
A new study has shown that it is possible to predict long-term cancer risk from a chemical exposure by measuring the short-term effects of that same exposure. The findings, which currently appear in the journal PLOS ONE, will make it possible to develop simpler and cheaper tests to screen chemicals for their potential cancer causing risk.
National Institutes of Health, Evans Center for Interdisciplinary Biomedical Research

Contact: Gina DiGravio
gina.digravio@bmc.org
617-638-8480
Boston University Medical Center

Public Release: 24-Jul-2014
JAMA Otolaryngology -- Head & Neck Surgery
Increased risk for head, neck cancers in patients with diabetes
Diabetes mellitus appears to increase the risk for head and neck cancer.
Taipei Medical University, Chi Mei Medical Center Research Fund

Contact: Yung-Song Li
kingear@gmail.com
The JAMA Network Journals

Public Release: 24-Jul-2014
Rhode Island Medical Journal
Miriam Hospital physician advocates awareness, collaboration to combat peaking hep C virus
Lynn E. Taylor, M.D., director of The Miriam Hospital's HIV/Viral Hepatitis Coinfection program, states in a commentary in the July, 2014 Rhode Island Medical Journal special edition, 'RI Defeats Hep C' that eliminating hepatitis C virus infection is feasible, can provide economic benefits, enhance capacity to address other health challenges, and improve health care disparities.

Contact: Elena Falcone-Relvas
efalconerelvas@lifespan.org
401-793-7484
Lifespan

Public Release: 24-Jul-2014
PLOS Computational Biology
Gene changes in breast cancer cells pinpointed with new computational method
Computer scientists at Carnegie Mellon University, working with high-throughput data generated by breast cancer biologists at Lawrence Berkeley National Laboratory, have devised a computational method to determine how gene networks are rewired as normal breast cells turn malignant and as they respond to potential cancer therapy agents.
NIH/National Institute of General Medical Sciences, NIH/National Cancer Institute, DOE/Breast Cancer Research Program

Contact: Byron Spice
bspice@cs.cmu.edu
412-268-9068
Carnegie Mellon University

Public Release: 24-Jul-2014
Oncotarget
Metastatic brain tumor treatment could be on the horizon with use of SapC-DOPS
A Cincinnati Cancer Center study, published in the advance online edition of the journal Oncotarget, provides hope that previously studied SapC-DOPS could be used for treatment of brain cancer that has spread.
UC Brain Tumor Molecular Therapeutics Program, UC College of Medicine, National Institutes of Health, New Drug State Key Project

Contact: Katie Pence
katie.pence@uc.edu
513-558-4561
University of Cincinnati Academic Health Center

Public Release: 24-Jul-2014
International Journal of Low Radiation
Natural products from plants protect skin during cancer radiotherapy
Plant-derived natural product chemicals could offer protection to the skin from the harmful effects of gamma radiation during cancer radiotherapy, suggests research published in the International Journal of Low Radiation.

Contact: Albert Ang
press@inderscience.com
Inderscience Publishers

Public Release: 24-Jul-2014
Cell Reports
Piggy-backing cells hold clue to skin cancer growth
Skin Cancer cells work together to spread further and faster, according to a new study published in Cell Reports.
Cancer Research UK

Contact: Alan Worsley
Alan.Worsley@cancer.org.uk
Cancer Research UK

Public Release: 24-Jul-2014
Cell Reports
A world first: Researchers identify a treatment that prevents tumor metastasis
Metastasis, the strategy adopted by tumor cells to transform into an aggressive form of cancer, are often associated with a gloomy prognosis. Managing to block the metastasis or to prevent their formation would be a giant step towards the fight against cancer. Researchers at Université catholique de Louvain in Belgium successfully performed this world first on models of human tumors in mice. The results of their study were published in the prestigious journal Cell Reports.
European Research Council Starting Grant, Fond de la Recherche Scientifique, Fondation Contre le Cancer

Contact: Prof. Pierre Sonveaux
pierre.sonveaux@uclouvain.be
32-495-251-739
Université catholique de Louvain

Public Release: 23-Jul-2014
British Journal of Cancer
No increased risk of cancer near Sellafield or Dounreay in recent years
Children, teenagers and young adults living near Sellafield or Dounreay since the 1990s are not at an increased risk of developing cancer according to research published in the British Journal of Cancer today.
Department of Health's Radiation Protection Research Programme

Contact: Alan Worsley
alan.worsley@cancer.org.uk
020-346-98252
Cancer Research UK

Public Release: 23-Jul-2014
JAMA Dermatology
Research led by Temple's chair of dermatology: Pain and itch may be signs of skin cancer
Asking patients if a suspicious skin lesion is painful or itchy may help doctors decide whether the spot is likely to be cancerous, according to a new study headed by Gil Yosipovitch, M.D., Chairman of the Department of Dermatology at Temple University School of Medicine. The study, published online by JAMA Dermatology on July 23, 2014, found that nearly 36.9 percent of skin cancer lesions are accompanied by itching, while 28.2 percent involve pain.
Comprehensive Cancer Center at Wake Forest

Contact: Jeremy Walter
Jeremy.Walter@tuhs.temple.edu
267-838-0398
Temple University Health System

Public Release: 23-Jul-2014
Nature
New regions of genetic material are involved in the development of colon cancer
Most research on human cancer genes have been focused on regions of the coding genome, but just before each gene, there is a regulatory region which controls the expression and activity of the adjacent gene. Until now, very little was known of the role exerted such DNA fragment in tumor development. An article published today in Nature in collaboration with the group of Manel Esteller shows that these regions are also altered in cancer.

Contact: Arantxa Mena
amena@idibell.cat
0034-932-607-282
IDIBELL-Bellvitge Biomedical Research Institute

Public Release: 23-Jul-2014
Stem Cells and Development
New method for reducing tumorigenicity in induced pluripotent stem-cell based therapies
The potential for clinical use of induced pluripotent stem cell (iPSC) technology for transplant-based therapeutic strategies has previously been hindered by the risk of dysregulated cell growth, specifically the development of tumors.

Contact: Kathryn Ruehle
kruehle@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 23-Jul-2014
Reproductive Biology and Endocrinology
Hormones after breast cancer: Not fuel for the fire after all?
Study highlights beneficial effects of non-oral hormone therapy on cardiac and bone outcomes, tumor reduction, and overall health in postmenopausal breast cancer mouse model.
Parsemus Foundation

Contact: Elaine Lissner
pr@parsemusfoundation.org
415-839-6304
Parsemus Foundation

Public Release: 23-Jul-2014
Nature Genetics
Vanderbilt-led study identifies genes linked to breast cancer in East Asian women
A new study in East Asian women has identified three genetic changes linked to an increased risk of breast cancer. The research, led by Vanderbilt University investigators, was published in Nature Genetics.
National Institutes of Health, Department of Defense, Vanderbilt-Ingram Cancer Center

Contact: Dagny Stuart
dagny.stuart@vanderbilt.edu
615-322-4747
Vanderbilt University Medical Center

Showing releases 201-225 out of 1244.

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