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Showing releases 226-250 out of 1420.

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Public Release: 24-Jun-2016
Journal of General Internal Medicine
UTSW research: Primary care visits result in more colon cancer screening, better followups
People who visit their primary care physicians are more likely to get potentially life-saving colon cancer screenings and follow up on abnormal stool blood test results -- even in health systems that heavily promote mail-in home stool blood tests that don't require a doctor visit, a study involving UT Southwestern population health researchers shows.

Contact: Lori Sundeen Soderbergh
UT Southwestern Medical Center

Public Release: 24-Jun-2016
Applied and Environmental Microbiology
Beneficial bacteria may protect breasts from cancer
Bacteria that have the potential to abet breast cancer are present in the breasts of cancer patients, while beneficial bacteria are more abundant in healthy breasts, where they may actually be protecting women from cancer, according to Gregor Reid, Ph.D., and his collaborators. These findings may lead ultimately to the use of probiotics to protect women against breast cancer.

Contact: Aleea Khan
American Society for Microbiology

Public Release: 24-Jun-2016
Science Advances
Cross talk between hormone receptors has unexpected effects
Although the estrogen receptor is considered dominant in breast cancer, the progesterone receptor assumes control when both receptors are present and exposed to estrogens and progestins. Then, the progesterone receptor drives estrogen receptor activity. Treating tumor-bearing mice with an estrogen antagonist and a progestin antagonist caused rapid tumor regression.
The Virginia and D. K. Ludwig Fund for Cancer Research, National Health and Medical Research Council of Australia, Cancer Prevention and Research Institute of Texas, and DOD/Breast Cancer Research Program

Contact: John Easton
University of Chicago Medical Center

Public Release: 24-Jun-2016
Scientific Reports
In mice, daughters of overweight dads have altered breast tissue, higher cancer risk
Obese male mice and normal weight female mice produce female pups that are overweight at birth through childhood, and have delayed development of their breast tissue as well as increased rates of breast cancer. The findings, published online June 24 in Scientific Reports by Georgetown Lombardi Comprehensive Cancer Center researchers, come from one of the first animal studies to examine the impact of paternal obesity on future generations' cancer risk.
American Cancer Society, Prevent Cancer Foundation

Contact: Karen Teber
Georgetown University Medical Center

Public Release: 24-Jun-2016
Top story for cancer research
A team of researchers led by Dr. Friederike J. Gruhl and Professor Andrew C. B. Cato at Karlsruhe Institute of Technology (KIT) are developing a three-dimensional model for prostate cancer research based on cryogels. The model will be used to reproduce natural processes and above all to examine the development and the progression of tumors. A current paper on this project published in the scientific journal Small (DOI: 10.1002/smll.201600683).

Contact: Monika Landgraf
Karlsruher Institut für Technologie (KIT)

Public Release: 23-Jun-2016
Cancer Prevention Research
Broccoli sprout extract may protect against oral cancer recurrence
Potent doses of broccoli sprout extract activate a 'detoxification' gene and may help prevent cancer recurrence in survivors of head and neck cancer, according to a 'green chemoprevention' trial by the University of Pittsburgh Cancer Institute, partner with UPMC CancerCenter. It is the first study demonstrating that the extract protects against oral cancer, with the results of human, animal and laboratory tests reported today.
NIH/National Cancer Institute, Lewis B. and Dorothy Cullman Foundation

Contact: Allison Hydzik
University of Pittsburgh Schools of the Health Sciences

Public Release: 23-Jun-2016
Scientific Reports
Mycobacterium in olive oil for cancer treatment
Researchers from the Universitat Autònoma de Barcelona and the Institute for Bioengineering of Catalonia have revealed a way to effectively deliver a mycobacterium needed for the treatment of bladder cancer in humans. The method, based on an emulsion using olive oil and tested on mice, was recently published in the journal Scientific Reports.

Contact: Esther Julián
Universitat Autonoma de Barcelona

Public Release: 23-Jun-2016
Cell Reports
Discovery of an epigenetic regulator of tumorigenesis suggests new strategies against
Mount Sinai scientists have identified a previously unknown mechanism by which a protein called CBX8 promotes tumor growth in the most lethal forms of breast cancer. The study, published today in the journal Cell Reports, underscores the need for cancer researchers to pay more attention to 'epigenetic' factors, meaning chemical and biological processes that control gene expression without changing the underlying DNA sequence of the cells that are running amok.
NIH/Office of Research Infrastructure, Department of Defense Breast Cancer Research Program, New York Stem Cell Foundation

Contact: Lorinda Klein
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 23-Jun-2016
A strategy for 'convergence' research to transform biomedicine
A new MIT report calls for increased support of 'convergence research,' which integrates physical and life sciences for revolutionary advances in biomedical research.
Raymond and Beverly Sackler Foundation, Kavli Foundation, Burroughs Wellcome Fund

Contact: Sarah McDonnell
Massachusetts Institute of Technology

Public Release: 23-Jun-2016
Cancer Epidemiology, Biomarkers & Prevention
Adherence to cancer prevention guidelines may reduce risk
Following cancer prevention guidelines on diet and physical activity consistently reduced overall cancer incidence and mortality, as well as reducing risk of breast, endometrial, and colorectal cancers.
NIH/National Cancer Institute

Contact: Lauren Riley
American Association for Cancer Research

Public Release: 23-Jun-2016
Nature Communications
Unexpected findings reveal insight into how cancer spreads in the body
Cancer cells appear to depend on an unusual survival mechanism to spread around the body, according to an early study led by Queen Mary University of London. The discovery could help with future development of novel treatments to prevent metastasis and secondary tumors.
UK Medical Research Council, Breast Cancer Now, Rosetrees Trust, British Lung Foundation, Cancer Research UK and Barts Charity

Contact: Joel Winston
Queen Mary University of London

Public Release: 23-Jun-2016
Cell Reports
The silencer: Study reveals how a cancer gene promotes tumor growth
A Yale-led study describes how a known cancer gene, EGFR, silences genes that typically suppress tumors. The finding, published in Cell Reports, may lead to the development of more effective, individualized treatment for patients with lung cancer and other cancer types.

Contact: Ziba Kashef
Yale University

Public Release: 23-Jun-2016
Cancer Cell
Researchers discover how faulty genetic instructions drive a deadly blood cancer in adults
A study by UNC Lineberger Comprehensive Cancer Center researchers uncovered the genetic mechanism for how acute myeloid leukemia cells with a specific DNA mutation stay as undifferentiated cells, rather than maturing into healthy blood cells.

Contact: Laura Oleniacz
UNC Lineberger Comprehensive Cancer Center

Public Release: 23-Jun-2016
Journal of the American Chemical Society
Rice scientists streamline synthesis of potential cancer drug
A team led by Rice University scientists has simplified the design and manufacture of a potent anti-tumor antibiotic known as uncialamycin.
National Institutes of Health, Skaggs Institute for Research, Cancer Prevention and Research Institute of Texas, The Welch Foundation, Bristol-Myers Squibb, US-UK Fulbright Commission

Contact: David Ruth
Rice University

Public Release: 23-Jun-2016
ACS Nano
Nanotechnology and math deliver two-in-one punch for cancer therapy resistance
Math, biology and nanotechnology are becoming strange, yet effective bed-fellows in the fight against cancer treatment resistance. Researchers at the University of Waterloo and Harvard Medical School have engineered a revolutionary new approach to cancer treatment that pits a lethal combination of drugs together into a single nanoparticle.

Contact: Nick Manning
University of Waterloo

Public Release: 23-Jun-2016
Annals of Rheumatic Diseases
New cancer immunotherapy drugs linked to arthritis in some patients
Case reports on 13 cancer patients suggest that a small number of cancer patients taking the immunotherapy drugs ipilimumab and nivolumab may be at some higher-than-normal risk of developing autoimmune joint and tissue diseases, including inflammatory arthritis, according to a preliminary study by Johns Hopkins Medicine researchers.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases, Jerome L. Greene Foundation

Contact: Marin Hedin
Johns Hopkins Medicine

Public Release: 23-Jun-2016
Journal of Medical Imaging and Radiation Sciences
Health-care providers do not fully understand cancer risk from CT scans
Doctors and other healthcare professionals may not be fully aware of a CT scan's effect on lifetime malignancy risk. A new study in the Journal of Medical Imaging and Radiation Sciences surveyed doctors, radiologists, and imaging technologists regarding their beliefs about radiation exposure from CT. The survey found that while most respondents recognized there is an increased risk of cancer from CT, many underestimated the actual radiation dose.

Contact: Chris Baumle
Elsevier Health Sciences

Public Release: 23-Jun-2016
Cell Reports
Novel gene-hunting method implicates new culprit in pancreatic cancer
Using an innovative approach to identify a cancer's genetic vulnerabilities by more swiftly analyzing human tumors transplanted into mice, researchers have identified a new potential target for pancreatic cancer treatment, published online in Cell Reports.

Contact: Scott Merville
University of Texas M. D. Anderson Cancer Center

Public Release: 23-Jun-2016
Journal of Neuroscience
An effective but painful treatment
Photodynamic therapy is an effective treatment for early-stage skin cancer. However, this therapy can cause patients severe pain. The reason for this was previous a mystery to researchers. Physiologists at Friedrich-Alexander Universität Erlangen-Nürnberg have now discovered that it is due to two specific ion channels.

Contact: Dr. Peter Reeh
University of Erlangen-Nuremberg

Public Release: 22-Jun-2016
The FEBS Journal
Low doses of common cancer drug may promote cancer spread
New research indicates that paclitaxel, which is the most commonly used chemotherapy for breast cancer, suppresses tumors when given at a certain dosage, but at low doses, it actually promotes cancer spread to the liver.

Contact: Penny Smith

Public Release: 22-Jun-2016
Sequencing method precise enough to reveal mechanisms by which bacteria resist antibiotics
A new technology can read the order (sequence) of the 'letters' making up DNA code with enough accuracy to reveal how bacteria use high-speed evolution to defeat antibiotics.
National Institutes of Health, Howard Hughes Medical Institute, Timur Artemyev

Contact: Greg Williams
NYU Langone Medical Center / New York University School of Medicine

Public Release: 22-Jun-2016
Cancer, violence among top health concerns for Chicago's South Siders
Residents on the South Side say cancer, violence prevention and sexually transmitted infections are among their top health concerns, according to a survey of 12 ZIP codes conducted by the University of Chicago Medicine. The 2016 Community Health Needs Assessment, published online in mid-June, also identifies diabetes among adults, pediatric asthma and pediatric obesity as other critical health issues faced by South Siders.

Contact: Lorna Wong
University of Chicago Medical Center

Public Release: 22-Jun-2016
Molecular Breeding
More reasons to eat your broccoli
Broccoli and related vegetables in the Brassica family are loaded with health-promoting compounds known as phenolics. Researchers have identified a large number of candidate genes controlling phenolic compound accumulation in broccoli. These genes will be used in future breeding programs to pack even more phenolic compounds into broccoli and other Brassica vegetables.
Hatch Multistate Project NC-7

Contact: Lauren Quinn
University of Illinois College of Agricultural, Consumer and Environmental Sciences

Public Release: 22-Jun-2016
Journal of Biomedical Optics
Light combined with time-based data sees more deeply inside the body
In a new article in the Journal of Biomedical Optics published by SPIE, the international society for optics and photonics, Antonio Pifferi and colleagues provide an overview of recent developments in light-based technologies that enable a deeper noninvasive look into the human body. The technologies hold promise to enable compact, wearable devices for point-of-care diagnostics and powerful new systems that provide even more information from under the skin.
European Commission

Contact: Amy Nelson
SPIE--International Society for Optics and Photonics

Public Release: 22-Jun-2016
American Journal of Preventive Medicine
Are older adults being appropriately screened for colorectal cancer?
In a study published in the American Journal of Preventive Medicine, researchers found that CRC screening, consistent with recommendations of the US Preventive Services Task Force, is not widely used by this segment of the population even though some patients are healthy and may benefit, and that appropriate follow-up is not taking place in a timely manner for some older adults.

Contact: Angela J. Beck
Elsevier Health Sciences

Showing releases 226-250 out of 1420.

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