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Showing releases 226-250 out of 1308.

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Public Release: 27-Oct-2015
UEG Week 2015
Improving risk profiling is key to preventing many GI cancers
Today, experts at United European Gastroenterology call for better risk profiling for all GI cancers in order to develop more targeted approaches to their screening and prevention.

Contact: Luke Paskins
Spink Health

Public Release: 27-Oct-2015
Environmental Health Perspectives
Lower doses of common product ingredient might increase breast cancer risk
Estrogen-mimicking chemicals called parabens may be more dangerous at lower doses than previously thought, according to a new study. The findings could have implications for the development of breast cancer and other diseases influenced by estrogens. The study also raises questions about current safety testing methods that may not predict the true potency of parabens and their effects on human health.

Contact: Alexandra Goho
617-332-4288 x232
Silent Spring Institute

Public Release: 27-Oct-2015
Scientific Reports
Researchers explore natural molecule's potential to aid immune response
Proteins called cytokines are known to influence immune cell fate, but the process is complex. Researchers examined how a specific cytokine, interleukin-15, influences gene expression patterns in T helper cells.

Contact: Paula Brewer Byron
Virginia Tech

Public Release: 27-Oct-2015
Drug for digestive problem can extend survival for many advanced cancer patients
Advanced cancer patients given a drug designed to relieve constipation caused by pain killers lived longer with less tumor progression than those who did not receive or respond to the drug, researchers report at the American Society of Anesthesiologists. This is the first study in humans to associate opioid blockade with longer survival. It suggests that methylnaltrexone, approved in 2008 for prevention of opioid-induced constipation, should play a larger role in cancer therapy.
University of Chicago

Contact: John Easton
University of Chicago Medical Center

Public Release: 27-Oct-2015
High-grade DCIS detection rates increase in older women
The mammography detection rate of an early-stage but potentially invasive type of breast cancer rises with age, according to a large new study.

Contact: Linda Brooks
Radiological Society of North America

Public Release: 27-Oct-2015
Nuclear Medicine Communications
One hundred cancer patients a year in Manchester benefit from new scan technology
Researchers in Manchester have used recent advances in PET scanning technology to reduce the radiation dose for both patients and staff by up to 30 percent, allowing an addition of an annual 100 scans a year at Central Manchester University Hospitals.

Contact: Jamie Brown
University of Manchester

Public Release: 27-Oct-2015
New finding offers clues for blocking cancer gene
A new study suggests a potential new way to block Notch, one of the most common cancer-causing genes, without causing severe side effects.
American Cancer Society, Elisa U. Pardee Foundation, Rally Foundation for Childhood Cancer Research, Vs. Cancer Foundation, Bear Necessities Pediatric Cancer Foundation, Concern Foundation, American Society of Hematology, National Institutes of Health

Contact: Nicole Fawcett
University of Michigan Health System

Public Release: 27-Oct-2015
UEG Week 2015
Increased risk of large bowel cancer for each 1 cm rise in waist circumference
New research shows an increased risk of large bowel cancer for each 1 cm rise in waist circumference. In addition, in men, there is now evidence that increasing waist circumference in middle age is associated with increased bowel cancer risk.

Contact: Luke Paskins
Spink Health

Public Release: 27-Oct-2015
Nature Communications
Genetic testing could identify men at a 10-fold increased risk of testicular cancer
A new study of more than 25,000 men has uncovered four new genetic variants associated with increased risk of testicular cancer. Testing for these variants combined with all 21 previously identified using genetic sequencing identified men with a 10-fold higher risk of testicular cancer than the population average.
Movember Foundation, Institute of Cancer Research, Cancer Research UK

Contact: Claire Hastings
Institute of Cancer Research

Public Release: 26-Oct-2015
Nature Communications
Scientists produce beneficial natural compounds in tomato -- industrial scale-up potential
As a result of the research led by Dr. Yang Zhang and Dr. Eugenio Butelli working in Professor Cathie Martin's lab at the John Innes Centre, one tomato can produce the same quantity of Resveratrol as exists in 50 bottles of red wine. One tomato has also produced the amount of Genistein found in 2.5kg of tofu.
Biotechnology and Biological Sciences Research Council, EU ATHENA collaborative project, Major State Basic Research Development Program (973 Program) of China, John Innes Foundation, DBT-CREST Fellowship

Contact: Geraldine Platten
John Innes Centre

Public Release: 26-Oct-2015
Nature Chemical Biology
Chemical probe to dissect role of potential cancer-causing proteins
Scientists have created a highly specific and well-characterised chemical probe which can switch off two important proteins implicated in cancer -- shedding new light on the role these proteins play in driving cancer cell proliferation.
Merck Serono, Cancer Research UK

Contact: Henry French
Institute of Cancer Research

Public Release: 26-Oct-2015
Canadian Medical Association Journal
New testosterone guideline to help Canadian physicians diagnose and treat patients
Controversy exists about how to manage patients with low testosterone, and many health care professionals are reluctant to treat testosterone deficiency, but a new guideline aims to provide a road map to help diagnose and treat this health condition. The guideline, created by the Canadian Men's Health Foundation and published in CMAJ (Canadian Medical Association Journal), targets primary care physicians, general internists, endocrinologists, geriatricians and urologists as well as psychiatrists, nurse practitioners and pharmacists who deal with men at or beyond middle age.
Canadian Men's Health Foundation

Contact: Kim Barnhardt
613-520-7116 x2224
Canadian Medical Association Journal

Public Release: 26-Oct-2015
Research explains limits of cancer immunotherapy drugs
A new study from the University of Michigan Comprehensive Cancer Center reveals molecular changes within a tumor that are preventing immunotherapy drugs from killing off the cancer.
National Institutes of Health, Rivkin Ovarian Cancer Center, Ovarian Cancer Research Fund, Barbara and Don Leclair

Contact: Nicole Fawcett
University of Michigan Health System

Public Release: 26-Oct-2015
Annals of Internal Medicine
Task Force says screen all overweight or obese adults for abnormal blood sugar
The US Preventive Services Task Force recommends screening overweight and obese adults between the ages of 40 and 70 for abnormal blood sugar. Patients found to have high blood sugar should be referred to intensive behavioral counseling interventions to promote a healthy diet and regular exercise. The recommendation is published in Annals of Internal Medicine.

Contact: Cara Graeff
American College of Physicians

Public Release: 26-Oct-2015
Study explores economic impact of cancer diagnoses on families
A new study illustrates some of the financial challenges that accompany a cancer diagnosis and highlights the need for efforts to mitigate the economic hardships associated with the disease.

Contact: Anna Zajacova
University of Wyoming

Public Release: 26-Oct-2015
American Academy of Pediatrics National Conference & Exhibition
American Academy of Pediatrics issues sweeping recommendations on tobacco and e-cigarettes
While adolescent use of tobacco has declined since the 1970s, it remains a persistent public health problem -- and e-cigarettes are threatening to addict a new generation to nicotine. In a comprehensive set of policies issued during its National Conference & Exhibition, the American Academy of Pediatrics (AAP) presents extensive recommendations to protect our nation's youth from the pernicious effects of tobacco and nicotine.

Contact: Debbie Jacobson
American Academy of Pediatrics

Public Release: 26-Oct-2015
A cancer diagnosis can lead to significant income losses for families
A new analysis indicates that when American adults are diagnosed with cancer, they experience significant decreases in the probability of working, in the number of hours they work, and correspondingly, in their incomes.

Contact: Dawn Peters

Public Release: 26-Oct-2015
New genetic discovery advances understanding of prostate cancer
A new and important genetic discovery, which sheds light on how prostate cancers develop and spread, has been made by an international research team led by scientists at The University of Nottingham.

Contact: Emma Rayner
University of Nottingham

Public Release: 26-Oct-2015
Proceedings of the National Academy of Sciences
Scientists devise new method to solve significant variables conundrum
Scientists at Columbia University, the University of California, San Diego and Harvard University have presented an alternative method to address the challenge of using significant variables to make useful predictions in areas such as complex disease.
National Science Foundation

Contact: Beth Kwon
Columbia University

Public Release: 26-Oct-2015
Biomaterials Science
WSU researchers develop natural protein cage for improved cancer drug delivery
Washington State University researchers have developed a unique, tiny protein cage to deliver nasty chemotherapy chemicals directly to cancer cells. Direct delivery could improve treatment and lessen what can be horrendous side effects from toxic drugs.
National Natural Science Foundation of China, Program for New Century Excellent Talents in University, Washington State University

Contact: Yuehe Lin
Washington State University

Public Release: 26-Oct-2015
Proceedings of the National Academy of Sciences
CRISPR/Cas9 used for rapid functional study of cancer-causing genes
A novel approach using the recently developed CRISP/Cas9 technique to switch off genes has been used for the first time to identify genes that cause liver cancer in adult mice. Rapid, scalable and flexible, this new method can identify novel cancer-causing genes, determine which combinations cause cancer and model development of cancer in adults. The team show that CRISPR/Cas9 can be used to induce and study liver cancer, the sixth most prevalent cancer worldwide.
German Cancer Consortium, Helmholtz Gemeinschaft

Contact: Samantha Wynne
Wellcome Trust Sanger Institute

Public Release: 26-Oct-2015
Future Medicinal Chemistry
UGA researchers discover mechanism that could lead to better ovarian cancer treatment
Resistance to chemotherapy is a major problem for those suffering from ovarian cancer -- a problem that prevents a cure from a disease dubbed the 'silent killer.' University of Georgia researchers are giving patients new hope with recent findings that help pinpoint the mechanisms causing chemoresistance.
NIH/National Cancer Institute, American Cancer Society, Georgia Research Alliance, Marsha Rivkin Center for Ovarian Cancer Research

Contact: Mandi Murph
University of Georgia

Public Release: 26-Oct-2015
Massive screen of drug combinations may find treatment for resistant, BRAF-mutant melanoma
A team of Massachusetts General Hospital investigators has discovered a new combination of drugs that may be effective against one of the deadliest cancers, malignant melanoma. The combination -- pairing a drug targeted against mutations in the BRAF gene with a second drug that targets another important signaling pathway -- was discovered through one of the largest screens of cancer drug combinations conducted to date.
National Institutes of Health

Contact: Katie Marquedant
Massachusetts General Hospital

Public Release: 26-Oct-2015
Nature Communications
Molecular motor grows cell's microtubules
Motor proteins that pause at the ends of microtubules and produce pushing forces can also stimulate their growth, according to researchers at Penn State. The proteins' function could be a critical component in understanding cell division and nerve branching and growth.
NIH/National Institute of General Medical Sciences

Contact: A'ndrea Elyse Messer
Penn State

Public Release: 26-Oct-2015
ESGO 2016
PharmaMar to present new studies for YONDELIS and PM1183 in ovarian cancer
PharmaMar introduces several posters to show clinical data about the treatment combining YONDELIS® with PLD in different patient profiles.

Contact: Carolina Pola

Showing releases 226-250 out of 1308.

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