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Showing releases 226-250 out of 1285.

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Public Release: 11-Jan-2016
Applied Physics Letters
Two-in-one packaging may increase drug efficacy and reduce side effects
Researchers have developed a speedy, controllable way to get two or more ingredients into the same tiny capsule and only have them mix when triggered by a signal like vibrations or heat.

Contact: Jason Socrates Bardi
jbardi@aip.org
240-535-4954
American Institute of Physics

Public Release: 11-Jan-2016
Cancer
What's in store for survivors of childhood cancers that affect vision?
Little is known about the long-term health of survivors of childhood cancers that affect vision, but two new studies provide valuable insights that could impact patient care and follow-up. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley

Public Release: 11-Jan-2016
Proceedings of the National Academy of Sciences
PNAS: Childhood leukemias forged by different evolutionary forces than in older adults
A University of Colorado Cancer Center paper published in the Proceedings of the National Academy of Sciences shows that the evolutionary force of genetic drift contributes to the ability of cancerous cells to overtake populations of healthy cells in young children. In contrast, genetic drift contributes almost not at all to leukemia formation in adults. The finding suggests important new avenues for leukemia treatment in very young patients.
NIH/National Cancer Institute, Linda Crnic Institute for Down Syndrome, Leukemia Lymphoma Society, St. Baldrick's Foundation

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Anschutz Medical Campus

Public Release: 11-Jan-2016
Annals of Internal Medicine
Making a safe procedure even safer
In a comprehensive modeling study, researchers from UC Davis and other institutions have found that breast cancer screening with digital mammography poses only a small risk of radiation-induced breast cancer for most women.
Agency for Healthcare Research and Quality, NIH/National Cancer Institute

Contact: Dorsey Griffith
dgriffith@ucdavis.edu
916-734-9118
University of California - Davis Health System

Public Release: 11-Jan-2016
Cancer Cell
McMaster researchers reveal predictive staircase to leukemia
In the paper published today by the scientific journal Cancer Cell, the researchers detail how they have been able to fingerprint myelodysplastic syndromes, a state for blood cells that turns into acute myeloid leukemia cancer in approximately 30 percent of patients.
Canadian Institutes of Health Research, Canadian Cancer Society Research Institute

Contact: Veronica McGuire
vmcguir@mcmaster.ca
905-525-9140
McMaster University

Public Release: 11-Jan-2016
Future of lung treatment: Malaysian scientists join Harvard team creating safe, effective nano drugs
Scientists from Malaysia are teaming with Harvard University experts to help revolutionize the treatment of lung diseases -- the safe, effective delivery of nanomedicine deep into parts of the lung unreachable using common inhalers. Other Malaysian Institute for Innovative Nanotechnology research pursuits include converting greenhouse gases into an energy source; 'Smart farming' nanosensors; more. The new national nanotech program, initiated through Malaysia's Global Science & Innovation Advisory Council, aims to make a macro impact in health, energy, environment, agriculture, electronics.

Contact: Terry Collins
tc@tca.tc
416-878-8712
Malaysian Industry-Government Group for High Technology

Public Release: 11-Jan-2016
Annals of Internal Medicine
USPSTF final recommendations on breast cancer screening
The US Preventive Services Task Force published a final recommendation statement on screening for breast cancer following an in-depth review of the science on the benefits and harms of screening mammography, and a detailed review of input received from the public and health care professionals on its 2015 draft recommendation.

Contact: Cara Graeff
cgraeff@acponline.org
215-351-2513
American College of Physicians

Public Release: 11-Jan-2016
Nature Methods
Linking gene expression and DNA methylation in single cells
A new single-cell genomics protocol allows researchers to study links between DNA modifications (methylation) and the activity of a gene. The method is the first to enable parallel profiling of the transcriptome and epigenome of a single cell. The researchers used the method to reveal new epigenome-transcriptome associations relevant to the regulation of pluripotency in mouse embryonic stem cells; The method is potentially transformative for epigenetics research, as it reveals unprecedented detail of the epigenetic control of genes.
Biotechnology and Biological Sciences Research Council, Wellcome Trust, European Molecular Biology Laboratory, Medical Research Council, European Commission

Contact: Mary Todd Bergman
mary@ebi.ac.uk
44-788-137-7941
European Molecular Biology Laboratory - European Bioinformatics Institute

Public Release: 11-Jan-2016
Annals of Internal Medicine
More research needed on evaluation of dense breasts
A systematic review of the scientific literature on dense breasts by researchers at UC Davis and other institutions has found that determinations of breast density can be unreliable and that as many as 19 percent of women are re-categorized as dense rather than non-dense or vice versa from one mammogram to the next.
Agency for Healthcare Research and Quality

Contact: Dorsey Griffith
dgriffith@ucdavis.edu
916-734-9118
University of California - Davis Health System

Public Release: 11-Jan-2016
Carcinogenesis
Researchers find shared molecular response to tobacco smoke and indoor air pollution
Exposure to certain household air pollutants may cause some of the same molecular changes as smoking cigarettes.
NIH/National Institute of Environmental Health Sciences, NIH/National Cancer Institute Intramural Research Program

Contact: Gina DiGravio
ginad@bu.edu
617-638-8480
Boston University Medical Center

Public Release: 11-Jan-2016
Molecular Oncology
Blood test that monitors dead cancer cell DNA better at tracking spread of melanoma
Physicians treating patients with metastatic melanoma -- one of the most aggressive forms of skin cancer -- may soon have a superior tool in their efforts to closely track the disease.

Contact: David March
david.march@nyumc.org
212-404-3528
NYU Langone Medical Center / New York University School of Medicine

Public Release: 11-Jan-2016
Annals of Internal Medicine
New analyses confirms biennial mammography starting at age 50 is optimal for average women
New and comprehensive analyses from six independent research teams examining breast cancer screening intervals have produced a unanimous finding -- that mammography screening every two years for average risk women ages 50 to 74 offers a favorable balance of benefits to harm.
National Institutes of Health

Contact: Karen Teber
km463@georgetown.edu
Georgetown University Medical Center

Public Release: 11-Jan-2016
Nature Cell Biology
Study reveals potential therapy targets for triple-negative breast cancer
In cancer, cell signaling pathways are the critical chain of events that can either quash or quicken disease progression.

Contact: Ron Gilmore
rlgilmore1@mdanderson.org
713-745-1898
University of Texas M. D. Anderson Cancer Center

Public Release: 11-Jan-2016
Journal of Thoracic Oncology
Stage increase in lung cancer more frequent after open vs. closed thoracic surgery
An increase in the stage of non-small cell lung cancer due to cancer positive lymph node discovery was more common following open chest surgery for lung lobe removal of early stage lung cancer compared to the closed chest procedure known as video assisted thoracic surgery.

Contact: Jeff Wolf
Jeff.Wolf@iaslc.org
720-325-2952
International Association for the Study of Lung Cancer

Public Release: 11-Jan-2016
ecancermedicalscience
Painkiller tapped to become future cancer-killer
Diclofenac, a common painkiller, has significant anti-cancer properties, according to researchers from the Repurposing Drugs in Oncology project. Like other drugs examined by the ReDO project, diclofenac is cheap and readily accessible -- and as it's already present in many medicine cabinets, it has been carefully tested.

Contact: Audrey Nailor
audrey@ecancer.org
44-117-403-3093
ecancermedicalscience

Public Release: 11-Jan-2016
Biotech Showcase
InSilico Medicine presents advances in deep learning for drug discovery and aging research
On Tuesday, Jan. 12, at 5:15 p.m. US ET, InSilico Medicine will present an update on recent advances in applying signaling pathway activation analysis and deep learning to drug discovery and drug repurposing for age-related diseases at the Biotech Showcase in San Francisco.

Contact: Qingsong Zhu
zhu@insilicomedicine.com
443-451-7212
InSilico Medicine, Inc.

Public Release: 11-Jan-2016
Public Health Reports
One hookah tobacco smoking session delivers 25 times the tar of a single cigarette
As cigarette smoking rates fall, more people are smoking tobacco from hookahs -communal pipes that enable users to draw tobacco smoke through water. A new meta-analysis led by the University of Pittsburgh School of Medicine shows that hookah smokers are inhaling a large load of toxicants.
NIH/National Cancer Institute

Contact: Allison Hydzik
HydzikAM@upmc.edu
412-647-9975
University of Pittsburgh Schools of the Health Sciences

Public Release: 10-Jan-2016
2016 Genitourinary Cancers Symposium
Even after anti-androgen therapy, docetaxel remains useful in prostate cancer
A study presented at the 2016 Genitourinary Cancers Symposium shows that 40 percent of patients with castration-resistant metastatic prostate cancer (mCRPC) treated with docetaxel following abiraterone had at least 50 percent reduction in prostate specific antigen (PSA), demonstrating the activity of this drug sequencing.
Genitourinary Cancers Symposium 2016

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Anschutz Medical Campus

Public Release: 8-Jan-2016
Mutation Research/Genetic Toxicology and Environmental Mutagenesis
BRCA1 deficiency increases the sensitivity of ovarian cancer cells to auranofin
An anti-rheumatic drug could improve the prognosis for ovarian cancer patients exhibiting a deficiency of the DNA repair protein BRCA1, a study led by Plymouth University has found.

Contact: Alan Williams
alan.williams@plymouth.ac.uk
0044-175-258-8004
University of Plymouth

Public Release: 8-Jan-2016
Science Advances
Scientists find key driver for treatment of deadly brain cancer
A factor in how malignant tumors spread may also be a key to treatment.

Contact: Salk Communications
press@salk.edu
858-453-4100
Salk Institute

Public Release: 8-Jan-2016
AIDS
Racial disparity lies at intersection of HIV, Hodgkin lymphoma
Among HIV-positive patients with Hodgkin lymphoma, a new study finds that blacks are significantly less likely than whites to receive treatment for the cancer, even though chemotherapy saves lives.
American Society of Hematology

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University

Public Release: 8-Jan-2016
New report finds no significant increase in health risks for 1960s Project SHAD veterans
Veterans who participated in a series of tests during the 1960s known as Project SHAD (Shipboard Hazard and Defense) show no significant increase in adverse health outcomes, specific causes of death, or death rates compared with a similar group of veterans who were not involved in the tests, says a new report from a committee of the National Academies of Sciences, Engineering, and Medicine.

Contact: Molly Galvin
news@nas.edu
202-334-2158
National Academy of Sciences

Public Release: 7-Jan-2016
Nature Chemistry
A 'printing press' for nanoparticles
Gold nanoparticles have unusual properties, which scientists are seeking to put to use in a range of technologies. Some of the most interesting properties emerge when nanoparticles are brought close together. But a major challenge has been finding ways to assemble these bits of gold while controlling the three-dimensional shape of their arrangement. In results reported in Nature Chemistry, researchers from McGill University outline a new technique.
Natural Sciences and Engineering Research Council of Canada, Canada Foundation for Innovation, Centre for Self-Assembled Chemical Structures, Canada Research Chairs Program, Canadian Institutes of Health Research

Contact: Chris Chipello
christopher.chipello@mcgill.ca
514-398-4201
McGill University

Public Release: 7-Jan-2016
Molecular Cell
Scientist identifies energy sensor as potential target for cancer drugs
An international research team formed by a University of Cincinnati cancer researcher has shown for the first time that a specific enzyme is responsible for sensing the available supply of GTP, an energy source that fuels the uncontrolled growth of cancer cells. The research underscores the enzyme's potential to become a therapeutic target for future cancer drugs.

Contact: Cindy Starr
cindy.starr@uc.edu
513-558-3505
University of Cincinnati Academic Health Center

Public Release: 7-Jan-2016
Clinical Cancer Research
Blocking melanoma's escape: Avatars break theraping resistance in relapsed cancers
By utilizing a revolutionary method that allows mice to serve as 'avatars' for patients, scientists at The Wistar Institute have shown that a previously ineffective targeted drug for melanoma may actually be quite potent in halting the progression of disease in certain patients.
Novartis, Dr. Miriam and Sheldon G. Adelson Medical Research Foundation

Contact: Ben Leach
bleach@wistar.org
215-495-6800
The Wistar Institute

Showing releases 226-250 out of 1285.

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