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Showing releases 226-250 out of 1243.

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Public Release: 24-Sep-2014
Proceedings of the National Academy of Sciences
A way to kill chemo-resistant ovarian cancer cells: Cut down its protector
Ovarian cancer is the most deadly gynecological cancer, claiming the lives of more than 50 percent of women who are diagnosed with the disease. A study involving Ottawa and Taiwan researchers, published in the influential Proceedings of the National Academy of Sciences, provides new insight into why ovarian cancer is often resistant to chemotherapy, as well as a potential way to improve its diagnosis and treatment.
Canadian Institutes of Health Research, National Science Council of Taiwan

Contact: Paddy Moore
padmoore@ohri.ca
613-737-8899 x73687
Ottawa Hospital Research Institute

Public Release: 24-Sep-2014
Journal of Clinical Investigation
Wound healing response promotes breast cancer metastasis in postpartum mice
A new study in the Journal of Clinical Investigation, suggests that dying tumor cells in postpartum breast tissue promote metastatic disease.

Contact: Corinne Williams
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 24-Sep-2014
BMJ Open
Skirt size increase linked to 33 percent greater postmenopausal breast cancer risk
Going up a skirt size over a period of 10 years between your mid 20s and mid 50s is linked to a 33 percent greater risk of developing breast cancer after the menopause, finds a large observational study published in the online journal BMJ Open.

Contact: Emma Dickinson
edickinson@bmj.com
44-020-739-36529
BMJ-British Medical Journal

Public Release: 24-Sep-2014
Annals of Surgical Oncology
Most breast cancer patients who had healthy breast removed at peace with decision
More women with cancer in one breast are opting to have both breasts removed to reduce their risk of future cancer. New research shows that in the long term, most have no regrets. Mayo Clinic surveyed hundreds of women with breast cancer who had double mastectomies between 1960 and 1993 and found that nearly all would make the same choice again. The findings are published in the journal Annals of Surgical Oncology.

Contact: Sharon Theimer
newsbureau@mayo.edu
507-284-5005
Mayo Clinic

Public Release: 24-Sep-2014
Organic & Biomolecular Chemistry
Scientists create new 'designer proteins' in fight against Alzheimer's and cancer
Chemists at the University of Leicester have reported a breakthrough in techniques to develop new drugs in the fight against diseases such as cancer and Alzheimer's.
Engineering and Physical Sciences research Council

Contact: Dr. Andrew Jamieson
andrew.jamieson@le.ac.uk
07-702-307-728
University of Leicester

Public Release: 24-Sep-2014
Journal of Clinical Oncology
Good news for young patients with a leukemia subtype associated with a poor prognosis
St. Jude Children's Research Hospital investigators found that adjusting treatment based on early response to chemotherapy made a life-saving difference to young patients with an acute lymphoblastic leukemia subtype associated with a poor outcome.
NIH/National Cancer Institute, NAtional Institutes of Health, National Health & Medical Research Council, Australia, Leukemia & Lymphoma Society, Alex's Lemonade Stand Foundation, Stand Up to Cancer, ALSAC

Contact: Carrie Strehlau
carrie.strehlau@stjude.org
901-595-2295
St. Jude Children's Research Hospital

Public Release: 24-Sep-2014
Journal of Thoracic Oncology
Modest acute changes in cardiac biomarkers and electrocardiogram findings following thoracic radiation therapy
There were only modest acute changes in cardiac biomarkers and electrocardiograms and there were no clinically significant cardiac events in patients with high-dose radiation exposure to the heart following thoracic radiation therapy and short-term follow-up.

Contact: Murry W. Wynes, Ph.D.
Murry.Wynes@IASLC.org
720-325-2945
International Association for the Study of Lung Cancer

Public Release: 24-Sep-2014
Journal of Thoracic Oncology
Less costly to screen for and treat early-stage lung than to treat late-stage lung cancer
The average cost to screen high-risk individuals for developing lung cancer with low-dose computed tomography plus the average cost of curative intent treatment, like surgery, is lower than the average cost to treat advanced stage lung cancer, which quite rarely results in a cure.

Contact: Murry W. Wynes, PhD
Murry.Wynes@IASLC.org
720-325-2945
International Association for the Study of Lung Cancer

Public Release: 23-Sep-2014
Computers for Biology and Medicine
New hope for beloved family pets
University of Leicester researchers work with Avacta Animal Health Ltd to develop novel system for diagnosing lymphoma in dogs.
Avacta Animal Health Ltd, East Midlands European Regional Development Fund

Contact: Professor Alexander Gorban
ag153@le.ac.uk
01-162-231-433
University of Leicester

Public Release: 23-Sep-2014
JAMA
Lung cancer test less effective in areas where infectious lung disease is more common
An analysis of 70 studies finds that use of the diagnostic imaging procedure of fludeoxyglucose F18-positron emission tomography combined with computed tomography may not reliably distinguish benign disease from lung cancer in populations with endemic (high prevalence) infectious lung disease compared with nonendemic regions, according to a study in the Sept. 24 issue of JAMA.

Contact: Craig Boerner
craig.boerner@vanderbilt.edu
615-322-4747
The JAMA Network Journals

Public Release: 23-Sep-2014
JAMA
Study questions accuracy of lung cancer screens in some geographic regions
A new analysis of published studies found that FDG-PET technology is less accurate in diagnosing lung cancer versus benign disease in regions where infections like histoplasmosis or tuberculosis are common. Misdiagnosis of lung lesions suspicious for cancer could lead to unnecessary tests and surgeries for patients, with additional potential complications and mortality.
Agency for Healthcare Research and Quality, National Institutes of Health, Department of Veterans Affairs

Contact: Craig Boerner
craig.boerner@vanderbilt.edu
615-322-4747
Vanderbilt University Medical Center

Public Release: 23-Sep-2014
Cancer Research
Study uncovers genetic driver of inflammation, uses it to prevent and treat liver cancer
Scientists at Virginia Commonwealth University Massey Cancer Center have demonstrated for the first time in preclinical studies that blocking the expression of a gene known as astrocyte elevated gene-1 halts the development and progression of liver cancer by regulating inflammation.
NIH/National Cancer Institute, James S. McDonnell Foundation

Contact: John Wallace
wallacej@vcu.edu
804-628-1550
Virginia Commonwealth University

Public Release: 23-Sep-2014
Journal of Women's Health
Opportunities to reduce patient burden associated with breast cancer screening
The many misperceptions about breast cancer screening options and risks, the benefits and costs of screening, and the need for new approaches and better education are discussed in a series of articles in a supplement to Journal of Women's Health.

Contact: Kathryn Ryan
kryan@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 23-Sep-2014
Pediatrics
Increased knowledge of HPV vaccines does not predict a higher rate of vaccination
A year-long study of over 360 adolescents who were considered to be ideal candidates to receive the HPV vaccine showed that neither increased parental or adolescent knowledge about HPV or the vaccine resulted in higher rates of vaccination. That is, those with higher levels of knowledge were not more likely to obtain vaccination for themselves or their daughters.
Pennsylvania Department of Health, American Cancer Society

Contact: Joseph J. Diorio
jdiorio@asc.upenn.edu
215-746-1798
University of Pennsylvania Annenberg School for Communication

Public Release: 23-Sep-2014
OncoImmunology
New anti-cancer peptide vaccines and inhibitors developed by Ohio State Researchers
Researchers have developed two new anticancer peptide vaccines and two peptide inhibitors as part of a larger peptide immunotherapy effort at The Ohio State University Comprehensive Cancer Center. The vaccines and inhibitors are designed to target the HER-3 and IGF-1R receptors, which are over-expressed in cancers of the breast, pancreas, esophagus and colon.
NIH/National Cancer Institute

Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Wexner Medical Center

Public Release: 23-Sep-2014
1st EORTC Cancer Survivorship Summit
European Journal of Cancer
Results of the 1st EORTC Cancer Survivorship Summit
A special issue of the European Journal of Cancer presents detailed reports on the wide range of research presented during the 1st EORTC Cancer Survivorship Summit held this past January in Brussels, Belgium.

Contact: John
john.bean@eortc.be
European Organisation for Research and Treatment of Cancer

Public Release: 22-Sep-2014
Cancer
E-cigarettes unhelpful in smoking cessation among cancer patients
In a new study of cancer patients who smoke, those using e-cigarettes, in addition to traditional cigarettes, were more nicotine dependent and equally or less likely to have quit smoking traditional cigarettes than non-users.

Contact: Evelyn Martinez
sciencenewsroom@wiley.com
Wiley

Public Release: 22-Sep-2014
Proceedings of the National Academy of Sciences
The fine line between breast cancer and normal tissues
Researchers at Brigham and Women's Hospital have successfully tested a tool they developed that will help surgeons better distinguish cancerous breast tissue from normal tissue, thereby decreasing the chances for repeat operations.
National Institutes of Health

Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-525-6383
Brigham and Women's Hospital

Public Release: 22-Sep-2014
Journal of Experimental Medicine
New rules for anticancer vaccines
Scientists have found a way to find the proverbial needle in the cancer antigen haystack. The results have the potential to completely change current approaches to generating anticancer vaccines.
Cancer Research Institute NY, Northeastern Utilities, Connecticut Institute for Clinical and Translational Science, SPARK, National Science Foundation, National Institutes of Health, Life Technologies, USDA/National Institute of Food and Agriculture

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press

Public Release: 22-Sep-2014
Cancer Research
Singapore researchers discover a gene that increases incidence of AML
A novel study by the Cancer Science Institute of Singapore at the National University of Singapore found that an increase in a gene known as Leo1 affects other genes that are directly implicated in acute myelogenous leukaemia, increasing the incidence of cancer.

Contact: Kimberley Wang
kimberley.wang@nus.edu.sg
65-660-11653
National University of Singapore

Public Release: 22-Sep-2014
Brain, Behavior and Immunity
Obesity and stress pack a double hit for health
If you're overweight, you may be at greater risk for stress-related diseases like type 2 diabetes, cardiovascular disease and cancer, according to a new study by Brandeis University. In a recently published paper in Brain, Behavior and Immunity, Brandeis researchers observed that overweight and obese individuals have higher levels of stress-induced inflammation than those within a healthy weight-range.
American Federation of Aging Research, National Institutes of Health

Contact: Leah Burrows
lburrows@brandeis.edu
781-736-4027
Brandeis University

Public Release: 22-Sep-2014
Cell Reports
Massachusetts General study reveals gene expression patterns in pancreatic CTCs
Analysis of circulating tumor cells in a mouse model of pancreatic cancer identified distinct patterns of gene expression in several groups of CTCs, including significant differences from the primary tumor that may contribute to the ability to generate metastases. The Massachusetts General Hospital Cancer Center investigators identified several different classes of pancreatic CTCs and found unexpected factors that may prove to be targets for improved treatment of the deadly tumor.
Stand Up to Cancer, Howard Hughes Medical Institute, Burroughs Wellcome Fund, NIH/National Institute of Biomedical Imaging and Bioengineering, NIH/National Cancer Institute, Affymetrix, Inc.

Contact: Katie Marquedant
kmarquedant@partners.org
617-726-0337
Massachusetts General Hospital

Public Release: 22-Sep-2014
Journal of Controlled Release
New chip promising for tumor-targeting research
Researchers have developed a chip capable of simulating a tumor's 'microenvironment' and plan to use the new system to test the effectiveness of nanoparticles and drugs that target cancer.
National Science Foundation, National Institutes of Health

Contact: Emil Venere
venere@purdue.edu
765-494-4709
Purdue University

Public Release: 22-Sep-2014
Gastroenterology
Good bowel cleansing is key for high-quality colonoscopy
The success of a colonoscopy is closely linked to good bowel preparation, with poor bowel prep often resulting in missed precancerous lesions, according to new consensus guidelines released by the US Multi-Society Task force on Colorectal Cancer. Additionally, poor bowel cleansing can result in increased costs related to early repeat procedures. Up to 20 to 25 percent of all colonoscopies are reported to have an inadequate bowel preparation.

Contact: Aimee Frank
media@gastro.org
301-941-2620
American Gastroenterological Association

Public Release: 21-Sep-2014
Nature Chemical Biology
Stanford researchers create 'evolved' protein that may stop cancer from spreading
Stanford researchers have created a decoy protein designed to interrupt the signaling pathway that triggers the breakaway of cancerous cells; in other words the signal that initiates metastasis. Preliminary tests showed this strategy effective in mice models; infusion with this decoy protein greatly reduced metastasis in mice with aggressive breast and ovarian cancers when compared to a control group. Years of tests lie ahead but it's a promising start for an alternative to chemotherapy.

Contact: Tm Abate
tabate@stanford.edu
650-736-2245
Stanford School of Engineering

Showing releases 226-250 out of 1243.

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