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Showing releases 226-250 out of 1212.

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Public Release: 25-Jun-2013
Journal of American College of Cardiology
Study shows heart failure survivors at greater risk for cancer
Heart failure patients are surviving more often with the heart condition but they are increasingly more likely to be diagnosed with cancer, a trend that could be attributed to increased surveillance, side effects of treatments, or other causes, according to a study published online today in the Journal of the American College of Cardiology

Contact: Rachel Cagan
rcagan@acc.org
202-375-6395
American College of Cardiology

Public Release: 25-Jun-2013
JAMA
Gene mutation may have effect on benefit of aspirin use for colorectal cancer
In 2 large studies, the association between aspirin use and risk of colorectal cancer was affected by mutation of the gene BRAF, with regular aspirin use associated with a lower risk of BRAF-wild-type colorectal cancer but not with risk of BRAF-mutated cancer, findings that suggest that BRAF-mutant colon tumor cells may be less sensitive to the effect of aspirin, according to a study in the June 26 issue of JAMA.

Contact: Jessica Maki
jmaki3@partners.org
617-534-1603
The JAMA Network Journals

Public Release: 25-Jun-2013
JAMA
Use of advanced treatment technologies for prostate cancer increases among men with low-risk disease
Use of advanced treatment technologies for prostate cancer, such as intensity-modulated radiotherapy and robotic prostatectomy, has increased among men with low-risk disease, high risk of noncancer mortality, or both, a population of patients who are unlikely to benefit from these treatments, according to a study in the June 26 issue of JAMA.

Contact: Justin Harris
juaha@umich.edu
734-764-2220
The JAMA Network Journals

Public Release: 25-Jun-2013
Journal of Thoracic Oncology
PET-CT improves care of limited-stage small-cell lung cancer patients
A study published in the July issue of the Journal of Thoracic Oncology, concludes that PET-CT improves staging accuracy and intrathoracic disease identification, which translates into an improvement in clinical outcome in these patients.

Contact: Kristal Griffith
Kristal.Griffith@iaslc.org
720-325-2952
International Association for the Study of Lung Cancer

Public Release: 25-Jun-2013
Journal of Medical Genetics
Mutua Madrileña funds IDIBELL and ICO project to improve diagnosis of Lynch syndrome
The Fundación Mutua Madrileña, in its 10th Call for Aids to Research, has selected a project to improve the diagnosis of Lynch syndrome led by researcher Marta Pineda, from the Hereditary Cancer research group of the Bellvitge Biomedical Research Institute and the Catalan Institute of Oncology. The aid is provided with 33,000 euros and has a duration of two years.

Contact: Arantxa Mena
comunicacio@idibell.cat
34-932-607-129
IDIBELL-Bellvitge Biomedical Research Institute

Public Release: 25-Jun-2013
Journal of Pathology
New study on popular prostate cancer protein provides insight into disease progression
Researchers at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute have uncovered for the first time the vital role a popular protein plays in the stroma, the cell-lined area outside of a prostate tumor.
NIH/National Cancer Institute

Contact: Cara Lasala
cara.lasala@cshs.org
310-423-7798
Cedars-Sinai Medical Center

Public Release: 25-Jun-2013
Journal of Thoracic Oncology
Continued research needed on treatment for women with lung cancer who are never smokers
A study published in the July issue of the Journal of Thoracic Oncology, concludes that lung cancer in women who have never smoked is more frequently associated with EGFR mutations and estrogen receptor overexpression.

Contact: Kristal Griffith
Kristal.Griffith@iaslc.org
720-325-2952
International Association for the Study of Lung Cancer

Public Release: 25-Jun-2013
PLOS ONE
Study details cancer-promoting mechanisms of overlooked components in secondhand smoke
A University of Colorado Cancer Center study published in the journal PLoS One shows that overlooked components of secondhand smoke may help the more well known molecules like BaP cause and promote cancer.
NIH/National Institute of Environmental Health Sciences, Colorado School of Public Health

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 25-Jun-2013
Journal of Thoracic Oncology
Immunohistochemistry effectively detects ALK rearrangement
A study published in the July issue of the Journal of Thoracic Oncology, concludes that immunohistochemistry can effectively detect ALK rearrangement in lung cancer. In fact, it might provide a reliable and cost-effective diagnostic approach in routine pathologic laboratories for the identification of suitable candidates for ALK-targeted therapy.

Contact: Kristal Griffith
Kristal.Griffith@iaslc.org
720-325-2952
International Association for the Study of Lung Cancer

Public Release: 25-Jun-2013
Nature Medicine
New screening approach identifies small proteins unique to melanoma cells, Moffitt researcher says
Jamie K. Teer, Ph.D., assistant member of the Cancer Biology and Evolution Program at Moffitt Cancer Center, and colleagues have developed a new streamlined method to rapidly identify the genetic changes in small protein fragments unique to melanoma cancer cells. These fragments can be used as targets for tumor-infiltrating lymphocytes that have been shown to reduce cancerous lesions.

Contact: Kim Polacek
kim.polacek@moffitt.org
813-745-7408
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 24-Jun-2013
Journal of Clinical Oncology
Study sets guidelines for stem cell transplants in older patients with myelodysplastic syndromes
Dana-Farber Cancer Institute scientists provide the first statistically-based guidelines for determining whether stem cell transplant is appropriate for patients older than 60 with myelodysplastic syndromes.

Contact: Teresa Herbert
teresa_herbert@dfci.harvard.edu
617-632-4090
Dana-Farber Cancer Institute

Public Release: 24-Jun-2013
Journal of Clinical Investigation
Modified immune cells seek and destroy melanoma
In this issue of the Journal of Clinical Investigation, researchers led by Scott Pruitt at Duke University and Merck Research Laboratories report on a human clinical trial in which modified dendritic cells, a component of the immune system, were tested in patients with melanoma.
Duke Clinical Research Institute, Duke Translational Medicine Institute, Duke Melanoma Consortium

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 24-Jun-2013
Journal of Clinical Investigation
JCI early table of contents for June 24, 2013
This release contains summaries, links to PDFs, and contact information for the following newsworthy releases to be published online, June 24, 2013, in the JCI: A prenatal trigger for postnatal obesity; Gene dysregulation underlies preeclampsia; The inflammatory consequences of chronic cannabis use; and many more.

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 24-Jun-2013
Nature Medicine
Brain cancer: Hunger for amino acids makes it more aggressive
An enzyme that facilitates the breakdown of specific amino acids makes brain cancers particularly aggressive. Scientists from the German Cancer Research Center discovered this in an attempt to find new targets for therapies against this dangerous disease. They have reported their findings in the journal "Nature Medicine."

Contact: Dr. Sibylle Kohlstädt
s.kohlstaedt@dkfz.de
Helmholtz Association

Public Release: 24-Jun-2013
Nature
Kidney cancer progression linked to shifts in tumor metabolism
Investigators in the Cancer Genome Atlas Research Network have uncovered a connection between how tumor cells use energy from metabolic processes and the aggressiveness of the most common form of kidney cancer, clear cell renal cell carcinoma.
NIH/National Cancer Institute

Contact: NCI Press Office
ncipressofficers@mail.nih.gov
301-496-6641
NIH/National Cancer Institute

Public Release: 24-Jun-2013
AcademyHealth Annual Research Meeting
Rural women less likely to get radiation therapy after lumpectomy for breast cancer
Rural women with breast cancer are less likely than their urban counterparts to receive recommended radiation therapy after having a lumpectomy, a breast-sparing surgery that removes only tumors and surrounding tissue, a study by Mayo Clinic and others found. The difference is one of several rural disparities in breast cancer diagnosis and treatment the researchers discovered. The findings are being presented at the AcademyHealth Annual Research Meeting in Baltimore.
National Institutes of Health

Contact: Shelly Plutowski
newsbureau@mayo.edu
507-284-5005
Mayo Clinic

Public Release: 24-Jun-2013
PLOS Computational Biology
Bacterial DNA may integrate into human genome more readily in tumor tissue
Bacterial DNA may integrate into the human genome more readily in tumors than in normal human tissue, scientists have found. The researchers, affiliated with the University of Maryland School of Medicine's Institute for Genome Sciences, analyzed genomic sequencing data available from the Human Genome Project, the 1,000 Genomes Project and the Cancer Genome Atlas.
National Science Foundation

Contact: Cheryl Dybas
cdybas@nsf.gov
703-292-7734
National Science Foundation

Public Release: 24-Jun-2013
International Journal of Cancer
Targeted viral therapy destroys breast cancer stem cells in preclinical experiments
A promising new treatment for breast cancer has been shown in cell culture and in animal models to selectively kill cancer stem cells at the original tumor site and in distant metastases with no toxic effects on healthy cells, including normal stem cells. Cancer stem cells are critical to a cancer's ability to recur following conventional chemotherapies and radiation therapy because they can quickly multiply and establish new tumors that are often therapy resistant.
NIH/National Cancer Institute

Contact: John Wallace
wallacej@vcu.edu
804-628-1550
Virginia Commonwealth University

Public Release: 23-Jun-2013
Nature Materials
Unexpected discovery of the ways cells move could boost understanding of complex diseases
A new discovery about how cells move may provide scientists with crucial information about disease mechanisms such as the spread of cancer or the constriction of airways caused by asthma. Led by researchers at Harvard School of Public Health and the Institute for Bioengineering of Catalonia investigators found that epithelial cells move in a group, propelled by forces both from within and from nearby cells, to fill any unfilled spaces they encounter.
National Institutes of Health, Spanish Ministry for Science and Innovation, Swiss National Science Foundation, American Heart Association

Contact: Marge Dwyer
mhdwyer@hsph.harvard.edu
617-432-8416
Harvard School of Public Health

Public Release: 23-Jun-2013
Nature
La Jolla Institute discovers new player critical to unleashing T cells against disease
A major study from researchers at the La Jolla Institute for Allergy and Immunology provides new revelations about the intricate pathways involved in turning on T cells, the body’s most important disease-fighting cells, and was published today in the prestigious scientific journal Nature. The La Jolla Institute team is the first to prove that a certain type of protein, called septins, play an essential role in T cell activation.

Contact: Bonnie Ward
contact@liai.org
619-991-0868
La Jolla Institute for Allergy and Immunology

Public Release: 23-Jun-2013
Proceedings of the National Academy of Sciences
New understanding of why anti-cancer therapy stops working at a specific stage
Researchers at the Hebrew University of Jerusalem and in California have achieved a breakthrough in understanding how and why a promising anti-cancer therapy has failed to achieve hoped-for success in killing tumor cells. Their work could lead to new insights into overcoming this impasse.

Contact: Jerry Barach
jerryb@savion.huni.ac.il
972-258-82904
The Hebrew University of Jerusalem

Public Release: 21-Jun-2013
Cancer Research
New Notre Dame paper offers insights into how cancer cells avoid cell death
A new study by a team of researchers from the University of Notre Dame provides an important new insight into how cancer cells are able to avoid the cell death process. The findings may suggest a chemotherapeutic approach to prevent the spread of cancers.

Contact: Zachary T. Schafer
zschafe1@nd.edu
574-631-0875
University of Notre Dame

Public Release: 20-Jun-2013
Cell Reports
CNIO researchers discover a new gene involved in obesity
This is the first time that a link has been found between telomeres and obesity. The study is published today in the journal Cell Reports.

Contact: Press Office
comunicacion@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)

Public Release: 20-Jun-2013
PLOS Computational Biology
Bacterial DNA may integrate into human genome more readily in tumor tissue
Bacterial DNA may integrate into the human genome more readily in tumors than in normal human tissue, according to a new study from the University of Maryland School of Medicine's Institute for Genome Sciences. Researchers analyzed genomic sequencing data available from the Human Genome Project, the 1,000 Genomes Project and The Cancer Genome Atlas. They considered the phenomenon of lateral gene transfe, the transmission of genetic material between organisms in the absence of sex.

Contact: Karen Robinson
karobinson@som.umaryland.edu
410-706-7590
University of Maryland Medical Center

Public Release: 20-Jun-2013
Cell
Researchers discover how a mutated protein outwits evolution and fuels leukemia
Scientists have discovered the survival secret to a genetic mutation that stokes leukemia cells, solving an evolutionary riddle and paving the way to a highly targeted therapy for leukemia. In a paper published today in Cell, researchers at NYU Langone Medical Center describe how a mutated protein, called Fbxw7, behaves differently when expressed in cancer cells versus healthy cells.

Contact: Christopher Rucas
Christopher.Rucas@nyumc.org
212-404-3525
NYU Langone Medical Center / New York University School of Medicine

Showing releases 226-250 out of 1212.

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