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Showing releases 26-50 out of 1311.

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Public Release: 25-Aug-2015
Environmental Chemistry Letters
Is incense bad for your health?
The burning of incense might need to come with a health warning. This follows the first study evaluating the health risks associated with its indoor use. The effects of incense and cigarette smoke were also compared, and made for some surprising results. The research was led by Rong Zhou of the South China University of Technology and the China Tobacco Guangdong Industrial Company in China, and is published in Springer's journal Environmental Chemistry Letters.

Contact: Joan Robinson
joan.robinson@springer.com
49-622-148-78130
Springer

Public Release: 25-Aug-2015
JAMA
Genetic mutations may help predict risk of relapse, survival for leukemia patients
In preliminary research, the detection of persistent leukemia-associated genetic mutations in at least 5 percent of bone marrow cells in day 30 remission samples among adult patients with acute myeloid leukemia was associated with an increased risk of relapse and reduced overall survival, according to a study in the Aug. 25 issue of JAMA.

Contact: Diane Duke Williams
williamsdia@wustl.edu
314-286-0111
The JAMA Network Journals

Public Release: 25-Aug-2015
JAMA
Relapse, poor survival in leukemia linked to genetic mutations that persist in remission
New research suggests that genome sequencing while a cancer patient is in remission can help physicians assess response to treatment and determine whether aggressive, follow-up treatment is necessary. The study, published Aug. 25 in JAMA, involved patients with acute myeloid leukemia.
National Institutes of Health, The Foundation for Barnes-Jewish Hospital

Contact: Jim Goodwin
jgoodwin@wustl.edu
314-286-0166
Washington University School of Medicine

Public Release: 25-Aug-2015
CANCER
New Moffitt study finds black women have higher frequency of BRCA mutations than previously reported
Moffitt Cancer Center researchers recently conducted the largest US based study of BRCA mutation frequency in young black women diagnosed with breast cancer at or below age 50 and discovered they have a much higher BRCA mutation frequency than that previously reported among young white women with breast cancer.
Florida Biomedical, American Cancer Society, Florida Breast Cancer Foundation, NIH/National Cancer Institute

Contact: Kim Polacek
Kimberly.Polacek@moffitt.org
813-745-7408
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 25-Aug-2015
Nature Communications
Injectable cryogel-based whole-cell cancer vaccines
New research led by Wyss Core Faculty member David Mooney could potentially yield a new platform for cancer vaccines. Leveraging a biologically inspired sponge-like gel called 'cryogel' as an injectable biomaterial, the vaccine delivers patient-specific tumor cells together with immune-stimulating biomolecules to enhance the body's attack against cancer. The approach, a so-called 'injectable cryogel whole-cell cancer vaccine,' is reported online in Nature Communications on Aug. 12.

Contact: Kat McAlpine
katherine.mcalpine@wyss.harvard.edu
617-432-8266
Wyss Institute for Biologically Inspired Engineering at Harvard

Public Release: 24-Aug-2015
CANCER
Generic heart medication shown to prolong ovarian cancer patients' survival
In a first-of-its-kind study, researchers demonstrate a benefit in overall survival among epithelial ovarian cancer patients receiving generic heart medications known as beta-blockers. Survival was shown to be greatest among those prescribed first-generation nonselective beta-blockers. According to The University of Texas MD Anderson Cancer Center investigators, the drugs block the effects of stress pathways involved in tumor growth and spread.

Contact: Laura Sussman
lsussman@mdanderson.org
713-745-2457
University of Texas M. D. Anderson Cancer Center

Public Release: 24-Aug-2015
Future Science OA
Future ScienceOA explores nitric oxide in medicine: Where are we, and where are we headed?
Future Science Group today announced the publication of a special issue in Future Science OA, covering the rapidly evolving field of nitric oxide in human medicine.

Contact: Leela Ripton
l.ripton@future-science-group.com
44-208-371-6090
Future Science Group

Public Release: 24-Aug-2015
Nature Cell Biology
Mayo Clinic researchers find new code that makes reprogramming of cancer cells possible
Cancer researchers dream of the day they can force tumor cells to morph back to the normal cells they once were. Now, researchers on Mayo Clinic's Florida campus have discovered a way to potentially reprogram cancer cells back to normalcy.
National Institutes of Health

Contact: Kevin Punsky
punsky.kevin@mayo.edu
904-953-0746
Mayo Clinic

Public Release: 24-Aug-2015
Annals of Internal Medicine
Long-term NSAID use may reduce CRC risk
Long-term, continuous use of low-dose aspirin and nonaspirin nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with decreased colorectal cancer risk. The findings of a population-based, case-control study are published in Annals of Internal Medicine.

Contact: Cara Graeff
cgraeff@acponline.org
215-351-2513
American College of Physicians

Public Release: 24-Aug-2015
Journal of the National Cancer Institute
Use of tamoxifen by young women is influenced by fertility concerns
The risk of breast cancer recurrence and mortality is decreased by endocrine therapy such as tamoxifen, but younger patients may decline it or discontinue treatment early if they are concerned about fertility, according to a study published Aug. 24 in the JNCI: Journal of the National Cancer Institute.

Contact: Zachary Rathner
Zachary.Rathner@oup.com
919-677-2697
Oxford University Press USA

Public Release: 24-Aug-2015
Journal of National Cancer Institute
Blood vessel cells help tumours evade the immune system
A new study by researchers at Sweden's Karolinska Institutet is the first to suggest that cells in the tumour blood vessels contribute to a local environment that protects the cancer cells from tumour-killing immune cells.
The Swedish Cancer Foundation, Strategic Cancer Research Program and BRECT Breast Cancer Theme Centrum at Karolinska Institutet, Swedish Research Council-supported STARGET Linneus Center of Excellence

Contact: KI Press Office
pressinfo@ki.se
46-085-248-6077
Karolinska Institutet

Public Release: 24-Aug-2015
CANCER
Heart medications that target stress may help prolong survival in women with ovarian cancer
A new analysis of patient records indicates that certain drugs taken to improve heart health may also have anti-cancer properties.

Contact: Evelyn Martinez
sciencenewsroom@wiley.com
Wiley

Public Release: 24-Aug-2015
Journal of the National Cancer Institute
Fertility concerns impact breast cancer treatment decisions
Concerns about fertility kept a third of young women with breast cancer from taking tamoxifen, despite its known benefit in reducing the risk of breast cancer coming back.
NIH/National Institute of Child Health and Human Development, Northwestern University/Medical Student Summer Research Program

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 24-Aug-2015
Pediatrics
Children's hospitals shift from CT scans for common childhood health problems
A study published online Aug. 24 by the journal Pediatrics finds a significant decrease in the use of computed tomography scans at children's hospitals for 10 common childhood diagnoses including seizure, concussion, appendectomy and upper respiratory tract infection. Study authors hypothesize the decline in CT usage may be attributable in part to a growing body of evidence linking ionizing radiation from CT scans to an increased risk of cancer in patients.

Contact: Nick Miller
nicholas.miller@cchmc.org
513-803-6035
Cincinnati Children's Hospital Medical Center

Public Release: 24-Aug-2015
Clinical Oncology
Electronic trigger reduces delays in evaluation for cancer diagnosis
Electronic triggers designed to search for key data, developed by researchers at Baylor College of Medicine and Michael E. DeBakey Veterans Affairs Medical Center, were able to identify and reduce follow-up delays for patients being evaluated for a diagnosis of colon or prostate cancer.
Agency for Healthcare Research and Quality, Houston Veterans Affairs HSR&D Center for Innovations in Quality, Effectiveness and Safety

Contact: Julia Parsons
julia.parsons@bcm.edu
713-798-4710
Baylor College of Medicine

Public Release: 24-Aug-2015
Gastroenterology
New study provides links between inflammation and colon cancer metastasis
A new Arizona State University research study led by Biodesign Institute executive director Raymond DuBois, M.D., Ph.D., has identified for the first time the details of how inflammation triggers colon cancer cells to spread to other organs, or metastasize.
National Institutes of Health, National Colorectal Cancer Research Alliance

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-258-8972
Arizona State University

Public Release: 24-Aug-2015
Veterinary Immunology and Immunopathology
Compound found in red wine causes conflicting changes in dogs' immune systems
Researchers at the University of Missouri have found that resveratrol does affect the immune systems of dogs in different ways when introduced to dogs' blood.

Contact: Nathan Hurst
hurstn@missouri.edu
573-882-6217
University of Missouri-Columbia

Public Release: 24-Aug-2015
Proceedings of the National Academy of Sciences
FSU researcher identifies protein with promise for cancer therapy
In the second part of his lab's recent one-two punch, Florida State University researcher Daniel Kaplan said he has solved a cell division mystery in a way that will intrigue the makers of cancer-fighting drugs.

Contact: Ronald Hartung
ronald.hartung@med.fsu.edu
850-645-9205
Florida State University

Public Release: 24-Aug-2015
Science
Scientists discover electrical control of cancer cell growth
The molecular switches regulating human cell growth do a great job of replacing cells that die during the course of a lifetime. But when they misfire, life-threatening cancers can occur. Research led by scientists at The University of Texas Health Science Center at Houston has revealed a new electrical mechanism that can control these switches.
Cancer Prevention & Research Institute of Texas, National Institutes of Health

Contact: Robert Cahill
Robert.Cahill@uth.tmc.edu
713-500-3030
University of Texas Health Science Center at Houston

Public Release: 24-Aug-2015
Human Gene Therapy
Optimizing effectiveness of CAR T cell therapy in lymphoma highlighted in special nordic issue
Chimeric antigen receptor T cells, which can specifically recognize and target tumor cells, have resulted in complete responses in patients with leukemia, and although equally promising for treating lymphoma, obstacles remain and individual patient responses CAR T cell therapy have varied. The main barriers to overcome in developing the next generation of CAR T cell therapy are presented in a Review article that is part of a special Nordic issue of Human Gene Therapy.

Contact: Kathryn Ryan
kryan@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 24-Aug-2015
Nature Neuroscience
Promising class of new cancer drugs might cause memory loss in mice
New research shows that a family of cancer drugs currently tested in patient trials can induce neurological changes in mice. The findings underscore the need for more research to determine whether these compounds can enter the brain, where they potentially might cause side effects such as memory loss.

Contact: Eva Kiesler
ekiesler@rockefeller.edu
212-327-7963
Rockefeller University

Public Release: 21-Aug-2015
BMC Medicine
Something to chew on -- millions of lives blighted by smokeless tobacco
More than a quarter of a million people die each year from using smokeless tobacco, researchers at the University of York have concluded.
Leeds City Council, Medical Research Council

Contact: Alistair Keely
alistair.keely@york.ac.uk
44-019-043-22029
University of York

Public Release: 20-Aug-2015
Journal of Nuclear Medicine
PET imaging detects fast-growing prostate cancer
A molecular imaging biomarker is able to detect fast-growing primary prostate cancer and distinguish it from benign prostate lesions, addressing an unmet clinical need. The new research, published in the July 2015 issue of The Journal of Nuclear Medicine, is significant for patients with suspected prostate cancer that has not been confirmed by standard biopsy.
Prostate Cancer Foundation, Radiological Society of North America Research and Education Foundation

Contact: Kimberly Brown
kbrown@snmmi.org
703-652-6773
Society of Nuclear Medicine

Public Release: 20-Aug-2015
Structure
Carnegie Mellon-led team identifies structure of tumor-suppressing protein
An international group of researchers led by Carnegie Mellon University physicists Mathias Lösche and Frank Heinrich have established the structure of an important tumor suppressing protein, PTEN. Their findings provide new insights into how the protein regulates cell growth and how mutations in the gene that encodes the protein can lead to cancer.
Department of Commerce, National Institutes of Health, NIH/National Institute of General Medical Sciences, NIH/National Institute of Neurological Disorders and Stroke, National Science Foundation, DOE/Office of Science, and others

Contact: Jocelyn Duffy
jhduffy@andrew.cmu.edu
412-268-9982
Carnegie Mellon University

Public Release: 20-Aug-2015
Nature Communications
TGen study finds genes associated with improved survival for pancreatic cancer patients
A study by the Translational Genomics Research Institute and other major research institutes, found a new set of genes that can indicate improved survival after surgery for patients with pancreatic cancer. The study also showed that detection of circulating tumor DNA in the blood could provide an early indication of tumor recurrence. In conjunction with the Stand Up To Cancer Pancreatic Cancer Dream Team, the study was published in Nature Communications.

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute

Showing releases 26-50 out of 1311.

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