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Showing releases 26-50 out of 1235.

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Public Release: 15-Oct-2014
Cancer Research
Prostate cancer's penchant for copper may be a fatal flaw
Like discriminating thieves, prostate cancer tumors scavenge and hoard copper that is an essential element in the body. But such avarice may be a fatal weakness.
National Institutes of Health

Contact: Sarah Avery
sarah.avery@duke.edu
919-660-1306
Duke University Medical Center

Public Release: 15-Oct-2014
New England Journal of Medicine
NEJM Perspective: 'The FDA, e-cigarettes, and the demise of combusted tobacco'
In this NEJM Perspective, two Georgetown University professors explore the popularity of E-cigarettes and point out that they could lead to the 'demise' of cigarette smoking and save thousands of lives, but not until they are proven safe and are regulated by the US Food and Drug Administration.

Contact: Karen Teber
km463@georgetown.edu
Georgetown University Medical Center

Public Release: 15-Oct-2014
Journal of Interferon & Cytokine Research
Pattern recognition receptors may be potent new drug targets for immune-mediated diseases
Chronic inflammation caused by activation of the human immune system contributes to a large and rapidly growing list of diseases including some cancers, cardiovascular disease, metabolic disorders, and autoimmune diseases. Significant advances in understanding the role that the cytokine-mediated JAK/STAT signaling network and pattern recognition receptors play in regulating immune responses and their potential as novel targets for developing potent new therapies are presented in a Review article in Journal of Interferon & Cytokine Research.

Contact: Kathryn Ryan
kryan@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 15-Oct-2014
Cancer Research
Two-faced gene: SIRT6 prevents some cancers but promotes sun-induced skin cancer
SIRT6 -- a protein that inhibits the growth of liver and colon cancers -- can promote the development of skin cancers by turning on an enzyme that increases inflammation, proliferation and survival of sun-damaged skin cells. This suggests that SIRT6 could provide a useful target for cancer prevention.
National Institutes of Health, American Cancer Society, University of Chicago Cancer Research Center

Contact: John Easton
john.easton@uchospitals.edu
773-795-5225
University of Chicago Medical Center

Public Release: 15-Oct-2014
New England Journal of Medicine
Personalized cellular therapy achieves complete remission in 90 percent of acute lymphoblastic leukemia patients studied
Ninety percent of children and adults with acute lymphoblastic leukemia who had relapsed multiple times or failed to respond to standard therapies went into remission after receiving an investigational personalized cellular therapy, CTL019, developed at the Perelman School of Medicine at the University of Pennsylvania. The results are published this week in The New England Journal of Medicine.
National Institutes of Health, Leukemia and Lymphoma Society, Stand Up To Cancer-St. Baldrick's Pediatric Dream Team Translational Research Grant

Contact: Holly Auer
holly.auer@uphs.upenn.edu
215-200-2313
University of Pennsylvania School of Medicine

Public Release: 15-Oct-2014
Gut
UK tops global league table for gullet cancer -- adenocarcinoma -- in men
The UK tops the international league table for a type of gullet (oesophageal) cancer, known as adenocarcinoma, in men, reveals a comprehensive estimate of the total number of new cases around the globe in 2012, and published online in the journal Gut. Worldwide, men are around four times as likely as women to develop the disease, the findings show.
World Cancer Research Fund

Contact: Emma Dickinson
edickinson@bmj.com
44-020-738-36529
BMJ-British Medical Journal

Public Release: 15-Oct-2014
Current Biology
Novel mechanism affecting cell migration discovered
The GMF protein controls the size and lifetime of protrusions in migrating cells.
Academy of Finland

Contact: Minna Poukkula
minna.poukkula@helsinki.fi
University of Helsinki

Public Release: 15-Oct-2014
JAMA Surgery
MD Anderson study first to compare treatments, survival benefits for early-stage lung cancer
Removal of the entire lobe of lung may offer patients with early-stage lung cancer better overall survival when compared with a partial resection, and stereotactic ablative radiotherapy may offer the same survival benefit as a lobectomy for some patients, according to a study from The University of Texas MD Anderson Cancer Center.

Contact: Laura Sussman
713-745-2457
University of Texas M. D. Anderson Cancer Center

Public Release: 15-Oct-2014
BMJ
New test can help doctors choose best treatment for ovarian cancer
Researchers have devized a new test to help doctors diagnose ovarian tumors and choose the most appropriate treatment.
Flemish Government: Research Foundation-Flanders, Flanders' Agency for Innovation by Science and Technology, iMinds, National Institute for Health Research Imperial Biomedical Research Centre

Contact: Sam Wong
sam.wong@imperial.ac.uk
44-207-594-2198
Imperial College London

Public Release: 14-Oct-2014
Clinical Cancer Research
University of Calgary research leads to brain cancer clinical trial
Researchers at the University of Calgary have made a discovery that could prolong the life of people living with glioblastoma -- the most aggressive type of brain cancer. The research was published in Clinical Cancer Research, and is leading researchers to start a human phase I/II clinical trial as early as spring 2015.
Alberta Cancer Foundation, Alberta Innovates-Health Solutions, Canadian Stem Cell Network

Contact: Marta Cyperling
mcyperli@ucalgary.ca
403-210-3835
University of Calgary, Faculty of Medicine

Public Release: 14-Oct-2014
Journal of Sexual Medicine
Side effects of cancer prevention surgery can be helped with education program
More women are having ovary-removing surgery as a cancer prevention measure, but many are often unaware of sexual or psychological side effects of the procedure. A new study by researchers at Dana-Farber Cancer Institute shows a half-day educational program can help successfully deal with these issues by educating women on how to address them.
NIH/National Cancer Institute

Contact: Anne Doerr
anne_doerr@dfci.harvard.edu
617-632-4090
Dana-Farber Cancer Institute

Public Release: 14-Oct-2014
Oncogene
Thyroid carcinoma: Biomarker reveals cancer cause
The expression of the protein CLIP2 provides information on whether a papillary thyroid carcinoma was induced by radiation or had a sporadic origin. With this discovery, scientists from the Helmholtz Zentrum München have identified a new biomarker for the diagnosis of the cancer cause. Their findings have been published in the journal 'Oncogene.'

Contact: Dr. Julia Heß
julia.hess@helmholtz-muenchen.de
49-893-187-3517
Helmholtz Zentrum München - German Research Center for Environmental Health

Public Release: 14-Oct-2014
PLOS Biology
Scientists find molecular 'breadcrumb trail' that helps melanoma spread
Cancer Research UK scientists have discovered that melanoma cells are drawn to follow the 'trail' of a naturally-occurring molecule in the body, which directs this serious type of skin cancer to spread, according to research publishing Tuesday Oct. 14 in the open access journal PLOS Biology.
Cancer Research UK

Contact: Press Office
biologypress@plos.org
PLOS

Public Release: 14-Oct-2014
Cancer
Study sheds light on factors that may contribute to pancreatic cancer
New research that provides a better understanding of pancreatic cancer may help identify individuals at increased risk.

Contact: Evelyn Martinez
sciencenewsroom@wiley.com
Wiley

Public Release: 14-Oct-2014
PLOS Biology
Scientists find molecular 'breadcrumb trail' that helps melanoma spread
Cancer Research UK scientists have discovered that melanoma cells are drawn to follow the 'trail' of a naturally-occurring molecule in the body, which directs this serious type of skin cancer to spread, according to research published in PLOS Biology.
Cancer Research UK

Contact: Emily Head
emily.head@cancer.org.uk
44-203-469-6189
Cancer Research UK

Public Release: 14-Oct-2014
Cancer
Early detection window when pancreatic cancer is in the family
Pancreatic cancer likely takes between 10 and 20 years to develop, providing the potential for a very 'broad window' of intervention if detected early, which may be possible for people who inherit a predisposition, say Australian clinical researchers.
National Health and Medical Research Council of Australia, Cancer Council NSW, Cancer Institute NSW, Queensland Government, Institute of Molecular Bioscience at the University of Queensland, Avner Nahmani Pancreatic Cancer Foundation

Contact: Alison Heather
a.heather@garvan.org.au
61-292-958-128
Garvan Institute of Medical Research

Public Release: 14-Oct-2014
New treatment designed to save more eyes from cancer
Doctors at Cincinnati Children's Hospital Medical Center have developed a new technique for treating the eye cancer retinoblastoma to improve the odds for preventing eye loss, blindness or death in children with advanced forms of the disease. The new procedure is credited saving the eyesight of a 4-year-old girl.

Contact: Nick Miller
nicholas.miller@cchmc.org
513-803-6035
Cincinnati Children's Hospital Medical Center

Public Release: 14-Oct-2014
Stem Cell Reports
Stem cell discovery challenges dogma on how fetus develops; holds insights for liver cancer and reg
A Mount Sinai-led research team has discovered a new kind of stem cell that can become either a liver cell or a cell that lines liver blood vessels, according to a study published today in the journal Stem Cell Reports.
Black Family Stem Cell Institute, NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Greg Williams
newsmedia@mssm.edu
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 14-Oct-2014
New treatment target identified for aggressive breast cancer
One of the first-known oncogenes has a protein partner that helps breast cancer proliferate and when it's blocked, so is the cancer, scientists report.

Contact: Toni Baker
tbaker@gru.edu
706-721-4421
Medical College of Georgia at Georgia Regents University

Public Release: 14-Oct-2014
Annals of Oncology
EMA open to discuss use of complementary methodologies for rare cancers
Rare Cancers Europe (RCE) is a multi stakeholder initiative promoted by ESMO dedicated to putting rare cancers on the European political agenda. In their consensus document, RCE argue that a higher degree of uncertainty should be accepted for regulatory as well as clinically informed decision-making in rare cancers, to overcome the limitations imposed by small population trials.

Contact: Rare Cancers Europe
rarecancerseurope@esmo.org
European Society for Medical Oncology

Public Release: 13-Oct-2014
PLOS ONE
Treating cancer: UI biologists find gene that could stop tumors in their tracks
UI researchers have found a gene in a soil amoeba that can overcompensate for the specific mutations of a similar gene. In humans, those genetic mutations can often lead to tumor growth. Researchers are now looking for a separate human gene that could overcompensate for mutations in the same way.
NIH/The Developmental Studies Hybridoma Bank

Contact: Brittany Borghi
brittany-borghi@uiowa.edu
319-384-0048
University of Iowa

Public Release: 13-Oct-2014
Cancer Research
Oral drug reduces formation of precancerous polyps in the colon, UB researchers find
Inflammatory cells in the colon, or polyps, are very common after the age of 50. The average 60-year-old has an estimated 25 percent chance of having polyps. Most polyps are benign, but some will develop into colon cancer. Now, an oral drug has successfully treated chronic, precancerous inflammation in the intestine in an animal study.
National Institutes of Health, Howard Hughes Medical Institute

Contact: Ellen Goldbaum
goldbaum@buffalo.edu
716-645-4605
University at Buffalo

Public Release: 13-Oct-2014
Proceedings of the National Academy of Sciences
Discovery of cellular snooze button advances cancer and biofuel research
The discovery of a cellular snooze button has allowed a team of Michigan State University scientists to potentially improve biofuel production and offer insight on the early stages of cancer.

Contact: Layne Cameron
layne.cameron@cabs.msu.edu
517-353-8819
Michigan State University

Public Release: 13-Oct-2014
Journal of Occupational and Environmental Medicine
QUT study helps outdoor workers reduce their skin cancer risk
Skin cancer is one of the biggest fears for one in two outdoor workers and when the boss and staff work together the sun safe message gets through, a QUT study has found.
Queensland Government

Contact: Sandra Hutchinson
s3.hutchinson@qut.edu.au
61-731-389-449
Queensland University of Technology

Public Release: 13-Oct-2014
Genome Research
PTPRZ-MET fusion protein: A new target for personalized brain cancer treatment
Researchers at the University of California, San Diego School of Medicine have identified a new fusion protein found in approximately 15 percent of secondary glioblastomas or brain tumors. The finding offers new insights into the cause of this cancer and provides a therapeutic target for personalized oncologic care.
Sontag Foundation, Burroughs Wellcome Foundation, Kimmel Foundation, Doris Duke Foundation, Forbeck Foundation

Contact: Jackie Carr
jcarr@ucsd.edu
619-543-6163
University of California - San Diego

Showing releases 26-50 out of 1235.

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