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Showing releases 26-50 out of 1365.

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Public Release: 28-Jul-2015
Nature Communications
Pitt study: Ancient proteins involved in DNA repair could shed light on tumor development
By studying yeast used in beer- and bread-making, researchers at the University of Pittsburgh School of Medicine have uncovered the mechanism by which ancient proteins repair DNA damage and how their dysfunction could lead to the development of tumors. The findings, published online today in Nature Communications, could lead to new ways to tailor cancer therapies.
National Institutes of Health

Contact: Anita Srikameswaran
SrikamAV@upmc.edu
412-578-9193
University of Pittsburgh Schools of the Health Sciences

Public Release: 28-Jul-2015
CA: A Cancer Journal for Clinicians
Cancer healthcare disparities exist in the LGBTQ community, say Moffitt researchers
Moffitt Cancer Center researchers published one of the first articles that describe the current knowledge about cancers that may disproportionately affect the LGBTQ community, and also offered suggestions for improving their healthcare.
NIH/National Cancer Institute

Contact: Kim Polacek
Kim.Polacek@Moffitt.org
813-745-7408
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 28-Jul-2015
Journal of National Cancer Institute
Race & institutional factors play an important role in pharmacogenomic trial participation
Moffitt Cancer Center researchers have published a study in the Journal of the National Cancer Institute that analyzed the participation rate of patients in pharmacogenomic trials.
NIH/National Cancer Institute, Cancer and Leukemia Group B

Contact: Kim Polacek
Kimberly.Polacek@moffitt.org
813-745-7408
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 28-Jul-2015
International Symposium on Geroprotectors
New methods for evaluating geroprotectors to be presented at the Basel Life Science Week 2015
The fight against aging has typically been focused on attacking the symptoms of aging such as physical decay and age-related diseases, but as the study of aging advances with more longevity researchers joining the fight each year strides are being taken to fight aging at its source. The most promising method is the identification of geroprotectors, compounds which can slow or even reverse the root causes of aging and extend the human life span.

Contact: Qingsong Zhu
zhu@insilicomedicine.com
443-451-7212
InSilico Medicine, Inc.

Public Release: 28-Jul-2015
Journal of Parenteral and Enteral Nutrition
Omega-3 fatty acids may help improve treatment and quality of life in cancer patients
Adding omega-3 fatty acids to anti-tumor medications may improve treatment response and quality of life for cancer patients according to a new study by researchers at the University Hospitals of Leicester in the United Kingdom.
B. Braun Melsungen

Contact: Troy Petenbrink
media@nutritioncare.org
202-297-1703
American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.)

Public Release: 28-Jul-2015
Nature Genetics
Ewing's sarcoma: A dangerous liaison
Researchers from Ludwig-Maximilians-Universitaet in Munich have elucidated at the molecular level how an otherwise innocuous inherited mutation that is quite common in European populations interacts with a spontaneous somatic mutation to promote the development of Ewing's sarcoma.

Contact: Luise Dirscherl
presse@lmu.de
0049-892-180-3423
Ludwig-Maximilians-Universität München

Public Release: 28-Jul-2015
Nature Genetics
Major European mouse study reveals the role of genes in disease
The role of over 300 genes has been revealed by scientists across Europe in a major initiative to understand the part they play in disease and biology. The results have now been published in the journal 'Nature Genetics'.
European Commission, Government of Canada through Genome Canada and Genome Prairie, French state funds through the 'Agence Nationale de la Recherche',

Contact: Martin Hrabe de Angelis
hrabe@helmholtz-muenchen.de
49-893-187-3502
Helmholtz Zentrum München - German Research Center for Environmental Health

Public Release: 27-Jul-2015
Proceedings of the National Academy of Sciences
Gene therapy may improve survival of patients with recurrent ovarian cancer
Use of gene therapy to deliver a protein that suppresses the development of female reproductive organs may improve the survival of patients with ovarian cancer that has recurred after chemotherapy, which happens 70 percent of the time and is invariably fatal.
Ovarian Cancer Research Fund, Sudna Gar Foundation, US Department of Defense, National Institutes of Health

Contact: Katie Marquedant
kmarquedant@partners.org
617-726-0337
Massachusetts General Hospital

Public Release: 27-Jul-2015
Oncogene
Study finds non-genetic cancer mechanism
Cancer can be caused solely by protein imbalances within cells, a study of ovarian cancer has found.
G. Harold and Leila Y. Mathers Charitable Foundation, National Institute of Health, RGK Foundation, Gilder Foundation

Contact: Chris Bunting
c.j.bunting@leeds.ac.uk
44-011-334-32049
University of Leeds

Public Release: 27-Jul-2015
Cancer
Many young cancer patients may have limited awareness of fertility preservation options
A new study points to the need for increased awareness of fertility preservation options for young patients with cancer.

Contact: Evelyn Martinez
sciencenewsroom@wiley.com
Wiley

Public Release: 27-Jul-2015
Proceedings of the National Academy of Sciences
Narrowing in on pituitary tumors
In a new study published in the Proceedings of the National Academy of Sciences on July 27, investigators from Brigham and Women's Hospital present a new technique that could help surgeons more precisely define the locations of pituitary tumors in near real-time.
National Institutes of Health, US Army Medical Research/CIMIT, National Center for Image Guided Therapy

Contact: Haley Bridger
hbridger@partners.org
617-525-6383
Brigham and Women's Hospital

Public Release: 27-Jul-2015
Journal of Clinical Investigation
Flow means 'go' for proper lymph system development
The lymph system provides a slow flow of fluid from tissues into the blood. It returns fluid and proteins that leak from blood vessels, provides passage for immune cells from the tissues to the blood, and hosts key niches for immune cells. How this system develops hasn't been well understood, but now researchers have found from that the early flow of lymph fluid is a critical factor in the development of mature lymphatic vessels.
National Institutes of Health, Leducq Foundation

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Public Release: 27-Jul-2015
Proceedings of the National Academy of Sciences
In CRISPR advance, scientists successfully edit human T cells
In a project spearheaded by investigators at UC San Francisco, scientists have devised a new strategy to precisely modify human T cells using the genome-editing system known as CRISPR/Cas9. Because these immune-system cells play important roles in a wide range of diseases, from diabetes to AIDS to cancer, the achievement provides a versatile new tool for research on T cell function, as well as a path toward CRISPR/Cas9-based therapies for many serious health problems.
National Institutes of Health, National MS Society, Howard Hughes Medical Institute

Contact: Pete Farley
peter.farley@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 27-Jul-2015
Nature Genetics
Yale study identifies 'major player' in skin cancer genes
A multidisciplinary team at Yale, led by Yale Cancer Center members, has defined a subgroup of genetic mutations that are present in a significant number of melanoma skin cancer cases. Their findings shed light on an important mutation in this deadly disease, and may lead to more targeted anti-cancer therapies.
Yale SPORE in Skin Cancer, NIH/National Cancer Institute, US National Institutes of Health, Melanoma Research Alliance, Gilead Sciences, Inc., Howard Hughes Medical Institute

Contact: Ziba Kashef
ziba.kashef@yale.edu
203-436-9317
Yale University

Public Release: 27-Jul-2015
Journal of Clinical Oncology
Breast cancer survivors who experience pain during intercourse may benefit from lidocaine
Scientists at Oregon Health & Science University report that breast cancer survivors who experience pain during sexual intercourse, a common side effect of breast cancer treatment, may achieve comfort when liquid lidocaine is applied strategically to prevent pain. Their research was published online today in the Journal of Clinical Oncology.
Oregon Health & Science University Center for Women's Health Circle of Giving

Contact: Ariane Le Chevallier
holma@ohsu.edu
503-494-8231
Oregon Health & Science University

Public Release: 27-Jul-2015
Tissue Engineering
Scientists' silk structure is secret to process of regenerating salivary cells
A research team led by Chih-Ko Yeh, B.D.S., Ph.D., from The University of Texas Health Science Center at San Antonio, is the first to use silk fibers as a framework to grow stem cells into salivary gland cells. The new process could provide relief for millions of individuals with dry mouth, including patients with Sjögren's syndrome, survivors of head and neck cancer, and those who take drugs with a side effect that limits saliva production.
NIH/National Institute of Dental and Craniofacial Research, Veterans Administration

Contact: Rosanne Fohn
fohn@uthscsa.edu
210-567-3026
University of Texas Health Science Center at San Antonio

Public Release: 27-Jul-2015
Cancer Discovery
Clinical validation for LOXO-101 against TRK fusion cancer
Published today in Cancer Discovery, first imaging studies conducted post-treatment, confirmed that stage IV patient's tumors had substantially regressed. With four months of treatment, additional CT scans demonstrated almost complete disappearance of the largest tumors.
V Foundation Scholar Award, Loxo Oncology Research Grant, State of Colorado and University of Colorado Technology Transfer Office Bioscience Discovery Evaluation Grant Program, University of Colorado Lung Cancer SPORE

Contact: Erika Matich
erika.matich@ucdenver.edu
University of Colorado Anschutz Medical Campus

Public Release: 27-Jul-2015
Lancet Haematology
New drug for blood cancers now in five phase II clinical trials
Researchers at University of California, San Diego School of Medicine have established the safety and dosing of a new drug for treating blood cancers. The findings are published online July 27 in The Lancet Haematology.
Pfizer, European Leukemia Net

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 27-Jul-2015
Cell Reports
In lab tests, new therapy slows spread of deadly brain tumor cells
The rapid spread of a common and deadly brain tumor has been slowed down significantly in a mouse model by cutting off the way some cancer cells communicate, according to a team of researchers that includes UF Health faculty.
American Cancer Society, National Institutes of Health, Sontag Foundation, Lerner Research Institute, Florida Center for Brain Tumor Research

Contact: Doug Bennett
dougbennett@ufl.edu
352-273-5706
University of Florida

Public Release: 27-Jul-2015
Nature Genetics
New treatment options for a fatal leukemia
In industrialized countries like in Europe, acute lymphoblastic leukemia is the most common form of cancer in children. An international research consortium lead by pediatric oncologists from the universities of Zurich and Hannover has now succeeded in decoding a specific form of this leukemia, which is regarded as incurable, and in obtaining insights for new therapeutic possibilities.

Contact: Jean-Pierre Bourqin
Jean-Pierre.Bourquin@kispi.uzh.ch
41-793-650-837
University of Zurich

Public Release: 24-Jul-2015
British Journal of Cancer
University of York scientists discover why some tumors are resistant to radiotherapy
Scientists at the University of York believe they have identified how some tiny regulatory molecules in cells can make prostate cancers resistant to radiotherapy. It is hoped that this new development could pave the way for more effective treatments -- allowing a lower dose of radiotherapy to be used while prolonging the lives of thousands of men.
PRO-NEST Marie Curie, The Finnish Funding Agency for Technology and Innovation Finland Distinguished Professor, and Academy of Finland, Cancer Research Technology and Yorkshire Cancer Research

Contact: David Garner
david.garner@york.ac.uk
44-019-043-22153
University of York

Public Release: 24-Jul-2015
Nature Communications
Scientists discover first 'DNA ambulance'
U of T researchers have discovered how severely damaged DNA is transported within a cell and how it is repaired. It's a discovery that could unlock secrets into how cancer operates -- a disease that two in five Canadians will develop in their lifetime.

Contact: Katie Babcock
Katie.Babcock@utoronto.ca
416-946-7707
University of Toronto

Public Release: 24-Jul-2015
Deutsches Ärzteblatt International
Prostate cancer not caused by shift work
In a recent original article in Deutsches Ärzteblatt International, Gael P. Hammer et al. show that shift workers do not develop prostate cancer more frequently than their colleagues who work during the day.

Contact: Dr. Gaël P. Hammer
gael.hammer@lns.etat.lu
Deutsches Aerzteblatt International

Public Release: 24-Jul-2015
Science Advances
TOPLESS plants provide clues to human molecular interactions
Van Andel Research Institute scientists have unraveled how an important plant protein, known as TOPLESS, interacts with other molecules responsible for turning genes off. The findings in plants provide a general model across species for this type of gene silencing, which is linked to several vital biological functions in humans.

Contact: Beth Hinshaw Hall
Beth.HinshawHall@vai.org
616-234-5519
Van Andel Research Institute

Public Release: 23-Jul-2015
JAMA
For prostate cancer patients, risk-specific therapies now more the norm
After decades of overtreatment for low-risk prostate cancer and inadequate management of its more aggressive forms, patients are now more likely to receive medical care matched to level of risk, according to a study by researchers at UC San Francisco.

Contact: Suzanne Leigh
Suzanne.Leigh@ucsf.edu
415-502-6397
University of California - San Francisco

Showing releases 26-50 out of 1365.

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