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Showing releases 26-50 out of 1250.

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Public Release: 14-Apr-2014
Cancer
Chemotherapy before or after surgery for high-risk bladder cancer improves survival, but is not routinely administered
Contrary to treatment guidelines for high-risk bladder cancer, chemotherapy before or after surgery is not commonly used in routine clinical practice.

Contact: Evelyn Martinez
sciencenewsroom@wiley.com
201-748-6358
Wiley

Public Release: 14-Apr-2014
Cancer Cell
'MicroRNA' could be key target for bowel cancer treatment
A tiny genetic molecule known as a microRNA plays a central role in bowel cancer and could be key to developing new treatments for the disease, a new study concludes.

Contact: Graham Shaw
graham.shaw@icr.ac.uk
44-207-153-5380
Institute of Cancer Research

Public Release: 14-Apr-2014
Cancer Cell
Study identifies a likely key driver of colorectal cancer development and progression
A new study identifies a molecule that is a probable driving force in colorectal cancer. The molecule could be an important target for colorectal cancer treatment and a valuable biomarker of tumor progression.
National Institutes of Health, Crohn's and Colitis Foundation of America

Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Wexner Medical Center

Public Release: 13-Apr-2014
Society for General Microbiology Annual Conference 2014
Reduction in HPV in young women in England seen, following national immunization program
A study conducted by Public Health England shows a reduction in two High Risk human papillomavirus types in sexually active young women in England, following the introduction of a national immunization program.

Contact: Francesca McNeil
infections-pressoffice@phe.gov.uk
44-020-832-77901
Society for General Microbiology

Public Release: 13-Apr-2014
Nature Genetics
Virus-fighting genes linked to mutations in cancer
All cancer-causing processes leave a distinct mutational imprint or signature on the genomes of patients. A team from the Wellcome Trust Sanger Institute has found a major piece of biological evidence to support the role a group of virus-fighting genes has in cancer development. The mutational signature left by the cancer-causing process driven by this family of genes is found in half of all cancer types.

Contact: Mary Clarke
press.office@sanger.ac.uk
44-012-234-95328
Wellcome Trust Sanger Institute

Public Release: 13-Apr-2014
Genetics & Development
Gene linked to pediatric kidney cancer suggests new strategies for kidney regeneration
Nearly one-third of cases of Wilms tumor, a pediatric cancer of the kidney, are linked to a gene called Lin28, according to research from Boston Children's Hospital. Mice engineered to express Lin28 in their kidneys developed Wilms tumor, which regressed when Lin28 was withdrawn, indicating that strategies aimed at blocking or deactivating the gene hold therapeutic promise. Studies also suggest that controlled expression of Lin28 can promote kidney development and therefore may hold clues to regeneration of damaged adult kidneys.
Ellison Medical Foundation and others

Contact: Irene Sege
irene.sege@childrens.harvard.edu
617-919-3110
Boston Children's Hospital

Public Release: 11-Apr-2014
Lancet Oncology
The Lancet Oncology: Challenges to effective cancer control in China, India, and Russia
New report from global cancer experts outlines barriers to cancer care and recent achievements in the three countries with more than half of the world's deaths from cancer.

Contact: Daisy Barton
daisy.barton@lancet.com
44-020-742-44949
The Lancet

Public Release: 11-Apr-2014
Nature Communications
Brain cell discovery could open doors to targeted cancer therapies
Fresh insights into the processes that control brain cell production could pave the way for treatments for brain cancer and other brain-related disorders.
Medical Research Council, Wellcome Trust

Contact: Catriona Kelly
Catriona.Kelly@ed.ac.uk
44-131-651-4401
University of Edinburgh

Public Release: 10-Apr-2014
International Liver Congress 2014
More evidence that NAFLD is an independent cardiovascular risk factor
Two new studies presented today at the International Liver Congress 2014 have provided more evidence to clarify the role of non-alcoholic fatty liver disease as an independent risk factor for the development of cardiovascular disease.

Contact: Courtney Lock
Courtney.Lock@cohnwolfe.com
44-789-438-6422
European Association for the Study of the Liver

Public Release: 10-Apr-2014
International Liver Congress 2014
New prediction model to improve patient survival after paracetamol-related liver failure
A new prediction model is to improve patient survival after paracetamol-related liver failure.

Contact: Courtney Lock
Courtney.Lock@cohnwolfe.com
44-789-438-6422
European Association for the Study of the Liver

Public Release: 10-Apr-2014
Biofabrication
3-D printing cancer cells to mimic tumors
A group of researchers in China and the US have successfully created a 3-D model of a cancerous tumor using a 3-D printer.

Contact: Michael Bishop
michael.bishop@iop.org
01-179-301-032
Institute of Physics

Public Release: 10-Apr-2014
Cell
Researchers identify transcription factors distinguishing glioblastoma stem cells
The activity of four transcription factors -- proteins that regulate the expression of other genes -- appears to distinguish the small proportion of glioblastoma cells responsible for the aggressiveness and treatment resistance of the deadly brain tumor.
Howard Hughes Medical Institute, Starr Cancer Consortium, Burroughs Wellcome Fund, Oncosuisse, Klarman Family Foundation

Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital

Public Release: 10-Apr-2014
Cell Metabolism
Lactate metabolism target halts growth in lung cancer model
A team led by investigators at Beth Israel Deaconess Medical Center has found that an enzyme responsible for the final step of glucose metabolism not only halts tumor growth in non-small-cell lung cancer, but actually leads to regression of established tumors.
National Institutes of Health, US Department of Defense

Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center

Public Release: 10-Apr-2014
American Association for Cancer Research (AACR) Annual Meeting 2014
AACR 2014 study highlights new drug, molecular insight into triple negative breast cancers
University of Colorado Cancer Center study presented today at the American Association for Cancer Research Annual Meeting 2014 showcased a new drug active against triple-negative breast cancer, and through analysis of the drug's mechanism of action, offers increased understanding of the biology of this very aggressive form of breast cancer.

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 10-Apr-2014
Journal of Men's Health
Therapeutic options and bladder-preserving strategies in bladder cancer
Men are three to four times more likely to get bladder cancer than women. The possible causes for this greater risk among men, the importance of early and accurate diagnosis, and the scope of available and emerging surgical, chemotherapeutic, and immunotherapeutic approaches for treating bladder cancer in men are the focus of a comprehensive Review article in Journal of Men's Health.

Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 10-Apr-2014
Cell Reports
Identified epigenetic factors associated with an increased risk of developing cancer
IDIBELL researchers show that one in four human tumor presents genetic polymorphisms associated with increased risk of cancer that cause an epigenetic change that modifies the expression of neighboring genes.
Blueprint, European Research Council, EPINORC project, MINECO, Genertalitat Catalunya

Contact: Arantxa Mena
amena@idibell.cat
34-932-607-282
IDIBELL-Bellvitge Biomedical Research Institute

Public Release: 10-Apr-2014
Nature Immunology
Enzyme revealed as promising target to treat asthma and cancer
In experiments with mice, Johns Hopkins Kimmel Cancer Center scientists have identified an enzyme involved in the regulation of immune system T cells that could be a useful target in treating asthma and boosting the effects of certain cancer therapies.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medicine

Public Release: 10-Apr-2014
Journal of Cancer Survivorship
Common sense health for young adult cancer survivors
Many factors influence the life expectancy of childhood cancer survivors: not getting enough exercise, being underweight, and being worried about their future health or their health insurance. These are the findings of research led by Cheryl Cox of the St. Jude Children's Research Hospital in the US, published in Springer's Journal of Cancer Survivorship. The study found that, on average, childhood cancer survivors passed away before they were 40 years old.

Contact: Alexander Brown
alexander.brown@springer.com
212-620-8063
Springer Science+Business Media

Public Release: 10-Apr-2014
American Association for Cancer Research (AACR) Annual Meeting 2014
Nature
Tumor-suppressor connects with histone protein to hinder gene expression
A tumor-suppressing protein acts as a dimmer switch to dial down gene expression. It does this by reading a chemical message attached to another protein that's tightly intertwined with DNA, a team led by scientists at the University of Texas MD Anderson Cancer Center reported at the AACR Annual Meeting 2014.

Contact: Scott Merville
smerville@mdanderson.org
713-792-0661
University of Texas M. D. Anderson Cancer Center

Public Release: 10-Apr-2014
Science
Yeast provides genetic clues on drug response
Why do people respond differently to the same drug? For the first time, researchers have untangled genetic and environmental factors related to drug reactions, bringing us a step closer to predicting how a drug will affect us.
National Institutes of Health

Contact: Heather Amos
heather.amos@ubc.ca
604-822-3213
University of British Columbia

Public Release: 10-Apr-2014
The Lancet
Scientists grow cartilage to reconstruct nose
Scientists at the University of Basel report first ever successful nose reconstruction surgery using cartilage grown in the laboratory. Cartilage cells were extracted from the patient's nasal septum, multiplied and expanded onto a collagen membrane. The so-called engineered cartilage was then shaped according to the defect and implanted. The results will be published in the current edition of the academic journal The Lancet.

Contact: Olivia Poisson
olivia.poisson@unibas.ch
University of Basel

Public Release: 9-Apr-2014
International Liver Congress 2014
EASL publishes online recommendations on the management of hepatitis C
The European Association for the Study of the Liver will this week be announcing new online recommendations on the management of hepatitis C at the International Liver Congress.

Contact: Courtney Lock
courtney.lock@cohnwolfe.com
44-789-438-6422
European Association for the Study of the Liver

Public Release: 9-Apr-2014
Journal of Clinical Investigation
Identified a new possible target to combat muscle wasting
The pathological atrophy of skeletal muscle is a serious biomedical problem for which no effective treatment is currently available. Those most affected populations are the elderly diagnosed with sarcopenia and patients with cancer, AIDS, and other infectious diseases that develop cachexia. A study by scientists at the Institute for Research in Biomedicine, headed by Antonio Zorzano, also full professor of the University of Barcelona, reveals a potential therapeutic target to tackle muscle wasting in these risk populations.
CIBERDEM, Ministry of Economy and Knowledge in Spain, EU/SUDOE programme

Contact: Sònia Armengou
armengou@irbbarcelona.org
34-934-037-255
Institute for Research in Biomedicine (IRB Barcelona)

Public Release: 9-Apr-2014
Clinical & Experimental Metastasis
TGen identifies growth factor receptors that may prompt metastatic spread of lung cancer
Two cell surface receptors might be responsible for the most common form of lung cancer spreading to other parts of the body, according to a study by the Translational Genomics Research Institute. The hepatocyte growth factor receptor and fibroblast growth factor-inducible 14 are proteins associated with the potential spread of non-small cell lung cancer, according to the TGen study published online April 8 by the scientific journal Clinical & Experimental Metastasis.
National Institutes of Health, St. Joseph's Foundation, American Lung Association

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute

Public Release: 9-Apr-2014
Nature Cell Biology
UNC researchers show how cancer cells may respond to mechanical force
Two UNC-Chapel Hill studies, published in Nature Cell Biology and the Journal of Immunology, identify the processes and cellular pathways that allow cells to move, stiffen, and react to physical stresses. This knowledge, researchers hope, could reveal the causes of cancer and help develop treatments, including therapies for a variety of diseases.
National Institutes of Health

Contact: William Davis
william_davis@med.unc.edu
919-966-5906
University of North Carolina Health Care

Showing releases 26-50 out of 1250.

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