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Showing releases 26-50 out of 1290.

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Public Release: 29-Apr-2016
Cancer Epidemiology, Biomarkers & Prevention
Exposure to particulate air pollutants associated with numerous types of cancer
Long-term exposure to ambient fine particulate matter, a mixture of environmental pollutants, was associated with increased risk of mortality for many types of cancer in an elderly Hong Kong population.
The Wellcome Trust

Contact: Lauren Riley
lauren.riley@aacr.org
215-446-7155
American Association for Cancer Research

Public Release: 29-Apr-2016
ESTRO 35
Is breast conserving therapy or mastectomy better for early breast cancer?
Young women with early breast cancer face a difficult choice about whether to opt for a mastectomy or breast conserving therapy (BCT). New research presented at the ESTRO 35 conference has shown young women, who had early stage breast cancer that had not spread to the lymph nodes and who opted for BCT with radiation therapy, had a 13 percent higher risk of developing a local recurrence of their disease over a 20-year period than women who had a mastectomy and no radiation therapy.
Danish Cancer Society, Danish Centre for Interventional Research in Radiation Oncology

Contact: Emma Mason
wordmason@mac.com
European Society for Radiotherapy and Oncology (ESTRO)

Public Release: 29-Apr-2016
ESTRO 35
Failure to publish trial results exposes patients to risks without providing benefits
Although the publication of results of clinical trials carried out in the USA within 12 months of their completion has been mandatory since 2007, an astoundingly high number of Phase III radiotherapy trials did not do so, according to new research to be presented at the ESTRO 35 conference. An analysis of 802 trials with a primary completion date of before Jan. 1, 2013, showed that 655, or 81.7 percent, did not publish even a summary result.

Contact: Mary Rice
mary.rice@riceconseil.eu
European Society for Radiotherapy and Oncology (ESTRO)

Public Release: 28-Apr-2016
Cancer Cell
TJP1 protein may identify multiple myeloma patients most likely to benefit from proteasome inhibitors
A gene known as TJP1 (tight junction protein 1) could help determine which multiple myeloma patients would best benefit from proteasome inhibitors such as bortezomib, as well as combination approaches to enhance proteasome inhibitor sensitivity, according to a study led by the University of Texas MD Anderson Cancer Center.

Contact: Ron Gilmore
rlgilmore1@mdanderson.org
713-745-1898
University of Texas M. D. Anderson Cancer Center

Public Release: 28-Apr-2016
Molecular Systems Biology
Scientists predict cell changes that affect breast cancer growth
Using a broad spectrum of analytical tools, scientists from the Florida campus of the Scripps Research Institute have shown how sometimes small, often practically imperceptible, structural changes in a key breast cancer receptor are directly linked to regulating molecules and can produce predictable effects in curbing or accelerating cancer growth.
National Institutes of Health, Frenchman's Creek Women for Cancer Research, BallenIsles Men's Golf Association, National Science Foundation, National Science Foundation of China, Key Project of Ministry of Education, and others

Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute

Public Release: 28-Apr-2016
Environmental Research
Study links residential radon exposure to hematologic cancers in women
A new report finds a statistically-significant, positive association between high levels of residential radon and the risk of hematologic (blood) cancer in women.
American Cancer Society

Contact: David Sampson
david.sampson@cancer.org
American Cancer Society

Public Release: 28-Apr-2016
Cancer
HPV vaccination expected to reduce cancer in all races, may not eliminate all disparities
Human papillomavirus (HPV)-associated cancers occur more frequently among Hispanics, blacks, American-Indians, and Alaska Natives than among whites. A new study from Harvard T.H. Chan School of Public Health finds that HPV vaccination is expected to reduce the cancer burden across all racial/ethnic groups. However, some disparities in cancer burden may persist and widen in the years to come if their causes, such as lack of access to diagnoses and treatment, aren't addressed.
NIH/National Cancer Institute

Contact: Marge Dwyer
mhdwyer@hsph.harvard.edu
617-432-8416
Harvard T.H. Chan School of Public Health

Public Release: 28-Apr-2016
JAMA Oncology
Recent cancer diagnosis associated with increased risk of mental health disorders
A recent cancer diagnosis was associated with increased risk for some mental health disorders and increased use of psychiatric medications, according to a new study published online by JAMA Oncology that used data from Swedish population and health registers.

Contact: Donghao Lu, M.D.
donghao.lu@ki.se
The JAMA Network Journals

Public Release: 28-Apr-2016
JAMA Oncology
Costs for orally administered cancer drugs skyrocket
New cancer drugs, taken in pill form, have become dramatically more expensive in their first year on the market compared with drugs launched 15 years ago, calling into question the sustainability of a system that sets high prices at market entry in addition to rapidly increasing those prices over time.

Contact: Thania Benios
thania_benios@unc.edu
919-962-8596
University of North Carolina at Chapel Hill

Public Release: 28-Apr-2016
Nature Materials
Shape of tumor may affect whether cells can metastasize
Only a few cells in a cancerous tumor are able to break away and spread to other parts of the body, but the curve along the edge of the tumor may play a large role in activating these tumor-seeding cells, according to a new University of Illinois study.
American Cancer Society, National Science Foundation

Contact: Liz Ahlberg
eahlberg@illinois.edu
217-244-1073
University of Illinois at Urbana-Champaign

Public Release: 28-Apr-2016
Cell Reports
A new discovery in the fight against cancer: Tumor cells switch to a different mode
When medication is used to shut off the oxygen supply to tumor cells, the cells adapt their metabolism in the medium term -- by switching over to producing energy without oxygen. This observation by biomedical scientists at the University of Basel and University Hospital Basel could be used for treatments that can inhibit tumor growth in the long term, as the researchers report in the latest issue of the journal Cell Reports.

Contact: Yannik Sprecher
yannik.sprecher@unibas.ch
41-612-672-424
University of Basel

Public Release: 28-Apr-2016
European Urology
Narrow band imaging can reduce recurrence of bladder tumors
Research into bladder tumor surgery has found that using narrow band imaging can significantly reduce the risk of disease recurrence.

Contact: Luke Harrison
l.harrison.1@bham.ac.uk
University of Birmingham

Public Release: 28-Apr-2016
Nature Structural & Molecular Biology
A long-noncoding RNA regulates repair of DNA breaks in triple-negative breast cancer cells
Using a clinically guided genetic screening approach, researchers identified a non-coding RNA that is overexpressed in triple-negative breast cancer cells and regulated by the tumor suppressor p53 and the activated cell surface protein, EGFR. This molecule enhances the repair of DNA breaks by serving as a scaffold that links two other proteins in the repair machinery.
University of Pennsylvania/Basser Center for BRCA, National Institutes of Health, Breast Cancer Alliance, Ovarian Cancer Research Fund, Foundation for Women's Cancer, Marsha Rivkin Center for Ovarian Cancer Research

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Public Release: 28-Apr-2016
Journal of Thoracic Oncology
Scientific advances in lung cancer in 2015 highlighted by IASLC
Capturing and summarizing the remarkable progress in lung cancer prevention, diagnosis, staging, and treatment in 2015, the International Association for the Study of Lung Cancer announces the inaugural publication of 'Scientific Advances in Lung Cancer 2015' in the May 2016 issue of the IASLC's Journal of Thoracic Oncology.

Contact: Jeff Wolf
Jeff.Wolf@iaslc.org
720-325-2952
International Association for the Study of Lung Cancer

Public Release: 28-Apr-2016
2016 Intelligent Systems for Molecular Biology (ISMB)
npj Genomic Medicine
Making precision medicine a reality: Genomics researchers unveil road map to disease origin
University of Arizona Health Sciences, University of Pennsylvania and Vanderbilt University researchers are one step closer to understanding the genetic and biological basis of diseases like cancer, diabetes, Alzheimer's and rheumatoid arthritis -- and to identifying new drug targets and therapies.
Computation Institute BEAGLE Cray Supercomputer of the University of Chicago and Argonne National Laboratory, NIH/National Library of Medicine, University of Arizona Cancer Center, University of Arizona Health Sciences, and others

Contact: Jean Spinelli
jspinell@email.arizona.edu
520-626-2531
University of Arizona Health Sciences

Public Release: 28-Apr-2016
Genome Medicine
Gut bacteria may predict risk of life-threatening infections following chemotherapy
A new study led by researchers at the University of Minnesota and Nantes University Hospital in France shows that the bacteria in people's gut may predict their risk of life-threatening blood infections following high-dose chemotherapy.
Nantes University Hospital, French National Society of Gastroenterology

Contact: Rhonda Zurn
rzurn@umn.edu
612-626-7959
University of Minnesota

Public Release: 28-Apr-2016
Human Mutation
New gene testing technology finds cancer risks 'hiding in plain sight'
A research team led by an award-winning genomicist at Western University has developed a new method for identifying mutations and prioritizing variants in breast and ovarian cancer genes, which will not only reduce the number of possible variants for doctors to investigate, but also increase the number of patients that are properly diagnosed.

Contact: Jeff Renaud
jrenaud9@uwo.ca
519-661-2111 x85165
University of Western Ontario

Public Release: 28-Apr-2016
Biophysical Journal
How cancer cells escape from tumors and spread
New research from a team led by Northeastern's Anand Astha­giri, asso­ciate pro­fessor of bio­engi­neering and chem­ical engi­neering, pro­vides an aston­ishing look at the bio­phys­ical prop­er­ties that permit breast cancer cells to 'slide' by obsta­cles and travel out of their pri­mary tumor toward a blood vessel that will carry them to a new site.

Contact: Casey Bayer
c.bayer@neu.edu
617-373-2592
Northeastern University

Public Release: 28-Apr-2016
Cell Metabolism
Study explains how low testosterone raises diabetes risk
Researchers have identified a key hormone-signaling pathway that explains why men with low testosterone are at greater risk for developing Type 2 diabetes, according to a new study in Cell Metabolism co-authored by Tulane University researchers.

Contact: Keith Brannon
kbrannon@tulane.edu
504-862-8789
Tulane University

Public Release: 28-Apr-2016
Journal of Women's Health
African-American women with ovarian cancer -- can obesity mask early symptoms?
African-American women with ovarian cancer are more likely to die from the disease than are White women and they are also much more likely to be obese. These factors may be linked by the new finding that excess abdominal fat in overweight and obese women could interfere with the detection of early symptoms of ovarian cancer, as presented in a study published in Journal of Women's Health.

Contact: Kathryn Ryan
kryan@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 27-Apr-2016
Nature
Scientists uncover new way to grow rare life-saving blood stem cells
A protein called Musashi-2 regulates the function and development of important blood stem cells. This knowledge provides new strategies that can be used to control the growth of these cells -- cells that can be used as therapeutics for a range of life-threatening diseases but are, in general, in very short supply.
Ontario Institute for Cancer Research, Canadian Institutes of Health Research, Canadian Blood Services, Health Canada, National Institutes of Health, California Institute for Regenerative Medicine

Contact: Veronica McGuire
vmcguir@mcmaster.ca
905-525-9140 x22169
McMaster University

Public Release: 27-Apr-2016
Oncotarget
Breast cancer progression -- the devil is in the detail
Researchers at Helmholtz Zentrum München describe how breast cancer cells challenged with a small-molecule inhibitor targeting specific invasive properties switch to an alternative mode-of-action, rendering them even more aggressive. The results may impair future therapeutic approaches in the TGF-beta pathway and are published in the journal Oncotarget.
German Cancer Aid Foundation

Contact: Dr. Christina Scheel
christina.scheel@helmholtz-muenchen.de
49-893-187-2012
Helmholtz Zentrum München - German Research Center for Environmental Health

Public Release: 27-Apr-2016
Journal of Clinical Investigation
Study: 93 percent of advanced leukemia patients in remission after immunotherapy
Twenty-seven of 29 patients with an advanced type of leukemia that had proved resistant to multiple other forms of therapy went into remission after their T cells (disease-fighting immune cells) were genetically engineered to fight their cancers. This study is the first CAR T-cell trial to infuse patients with an even mixture of two types of T cells (helper and killer cells, which work together to kill cancer).
NIH/National Cancer Institute, Juno Therapeutics, Life Sciences Discovery Fund, and others

Contact: Sandy Van
svan2@fredhutch.org
808-526-1708
Fred Hutchinson Cancer Research Center

Public Release: 27-Apr-2016
Urology
New model for active surveillance of prostate cancer tested
Urologists at University of California, San Diego School of Medicine and Genesis Healthcare Partners have tested a new model of care for patients with low-risk prostate cancer. The evidence-based approach uses best practices to appropriately select and follow patients to avoid disease overtreatment. Results of the three-year study are now published online in the journal of Urology.

Contact: Jackie Carr
jcarr@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 26-Apr-2016
Journal of Nanobiotechnology
Danish researchers behind vaccine breakthrough
A Danish research team from the University of Copenhagen has designed a simple technique that makes it possible to quickly and easily develop a new type of vaccines. The simple and effective technique will pave the way for effective vaccines against not only infectious diseases but also cancer and other chronic diseases.

Contact: Adam Sander
asander@sund.ku.dk
45-30-11-15-29
University of Copenhagen The Faculty of Health and Medical Sciences

Showing releases 26-50 out of 1290.

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