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Showing releases 26-50 out of 1136.

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Public Release: 28-Nov-2012
Journal of the National Cancer Institute
NSAID use linked to reduced hepatocellular carcinoma risk and mortality due to chronic liver disease
Researchers found that aspirin use is associated with a decreased risk of developing hepatocellular carcinoma and death from chronic liver disease, according to a study published Nov. 28 in the Journal of the National Cancer Institute.

Contact: Zachary Rathner
Zachary.Rathner@oup.com
301-841-1286
Journal of the National Cancer Institute

Public Release: 28-Nov-2012
Environmental Science and Technology
New study: Many flame retardants in house dust -- unsafe levels
In Silent Spring Institute's new peer-reviewed study of the largest number of flame retardants ever tested in homes, we found that most houses had levels of at least one flame retardant that exceeded a federal health guideline.
NIH/National Institute of Environmental Health Sciences, New York Community Trust, Fine Fund, Art beCAUS

Contact: Kathryn Rodgers
rodgers@silentspring.org
617-332-4288 x225
Silent Spring Institute

Public Release: 28-Nov-2012
New England Journal of Medicine
Ponatinib acts against the most resistant types of chronic myeloid leukemia
A previously invincible mutation in chronic myeloid leukemia has been thwarted by an investigational drug in a phase I clinical trial reported in the current edition of the New England Journal of Medicine.

Contact: Scott Merville
smerville@mdanderson.org
713-792-0661
University of Texas M. D. Anderson Cancer Center

Public Release: 28-Nov-2012
Journal of the National Cancer Institute
Combined RB and PTEN loss identifies DCIS primed for invasive breast cancer
The combined loss of two tumor suppressor genes, retinoblastoma and phosphatase and tensin homolog was shown to be strongly associated with progression of DCIS to invasive breast cancer, according to a study published Nov. 28 in the Journal of the National Cancer Institute.

Contact: Zachary Rathner
Zachary.Rathner@oup.com
301-841-1286
Journal of the National Cancer Institute

Public Release: 28-Nov-2012
Journal of the National Cancer Institute
KRAS and BRAF mutation screening in metastatic colorectal cancer costly in relation to benefits
Researchers report that screening for KRAS and BRAF mutations can reduce the cost of anti-EGFR treatment for metastatic colorectal cancer but with a very small reduction in overall survival according to a new study published on Nov. 28 in the Journal of the National Cancer Institute.

Contact: Zachary Rathner
Zachary.Rathner@oup.com
301-841-1286
Journal of the National Cancer Institute

Public Release: 28-Nov-2012
Nature
COUP-TFII sparks prostate cancer progression
Which cancers are essentially indolent and present no risk and which are life threatening? Which can be watched and which need aggressive treatment? Drs. Ming-Jer and Sophia Tsai both professors in the department of molecular and cellular biology at Baylor College of Medicine, think a receptor called COUP-TFII that they have long studied may point the way to an answer.

Contact: Dipali Pathak
pathak@bcm.edu
713-713-4710
Baylor College of Medicine

Public Release: 28-Nov-2012
Science Translational Medicine
Johns Hopkins scientists pair blood test and gene sequencing to detect cancer
Scientists at the Johns Hopkins Kimmel Cancer Center have combined the ability to detect cancer DNA in the blood with genome sequencing technology in a test that could be used to screen for cancers, monitor cancer patients for recurrence and find residual cancer left after surgery.
National Institutes of Health

Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medicine

Public Release: 28-Nov-2012
Potentially toxic flame retardants found in many US couches
More than half of all couches tested in a Duke University-led study contained potentially toxic or untested chemical flame retardants that may pose risks to human health.
NIH/National Institute of Environmental Health Sciences

Contact: Tim Lucas
tdlucas@duke.edu
919-613-8084
Duke University

Public Release: 27-Nov-2012
Radiological Society of North America 98th Scientific Assembly and Annual Meeting
Researchers identify physiological evidence of 'chemo brain'
Chemotherapy can induce changes in the brain that may affect concentration and memory, according to a new study. Using positron emission tomography combined with computed tomography, researchers were able to detect physiological evidence of chemo brain, a common side effect in patients undergoing chemotherapy for cancer treatment.

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America

Public Release: 27-Nov-2012
Radiological Society of North America 98th Scientific Assembly and Annual Meeting
New studies show effects of mammography guideline changes
Researchers assessing the impact of revised guidelines for screening mammography issued by the US Preventive Services Task Force found evidence that the new recommendations may lead to missed cancers and a decline in screening, according to two new studies.

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America

Public Release: 27-Nov-2012
Radiological Society of North America 98th Scientific Assembly and Annual Meeting
Breast cancer risk estimates increased with repeated prior ct and nuclear imaging
Researchers reviewing the records of approximately 250,000 women enrolled in an integrated healthcare delivery system found that increased CT utilization between 2000 and 2010 could result in an increase in the risk of breast cancer for certain women, including younger patients and those who received repeat exams. According to the study, nuclear medicine examinations may also contribute to increased breast cancer risk.

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America

Public Release: 27-Nov-2012
American Journal of Medical Genetics
Gene that causes tumor disorder linked to increased breast cancer risk
New Johns Hopkins research showing a more than four-fold increase in the incidence of breast cancer in women with neurofibromatosis-1 adds to growing evidence that women with this rare genetic disorder may benefit from early breast cancer screening with mammograms beginning at age 40, and manual breast exams as early as adolescence.
National Center for Research Resources

Contact: Stephanie Desmon
sdesmon1@jhmi.edu
410-955-8665
Johns Hopkins Medicine

Public Release: 27-Nov-2012
Radiological Society of North America 98th Scientific Assembly and Annual Meeting
Scatter radiation from mammography presents no cancer risk
The radiation dose to areas of the body near the breast during mammography is negligible, or very low, and does not result in an increased risk of cancer, according to a new study. The results suggest that the use of thyroid shields during mammography is unnecessary.

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America

Public Release: 27-Nov-2012
Radiological Society of North America 98th Scientific Assembly and Annual Meeting
Women with dense breasts welcome additional screening
A survey of women undergoing routine screening mammography found that many of them would be interested in pursuing additional screening tests if notified they had dense breast tissue, despite the possibility of false positives, invasive procedures, and out-of-pocket costs, according to a new study.

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America

Public Release: 27-Nov-2012
Tracking down smallest biomarkers
A new device is to provide the metrological basis for promising biomarkers. The vacuum-compatible version of the Pilatus hybrid pixel detector for X-rays, which was developed by Dectris in cooperation with the Physikalisch-Technische Bundesanstalt, allows the size of nano-particles -- which, to date, have been difficult to characterize -- to be determined using small-angle X-ray scattering at low photon energies.

Contact: Michael Krumrey
michael.krumrey@ptb.de
49-030-348-17110
Physikalisch-Technische Bundesanstalt (PTB)

Public Release: 27-Nov-2012
American Society of Clinical Oncology's Quality Care Symposium
Most women who have double mastectomy don't need it, U-M study finds
About 70 percent of women who have both breasts removed following a breast cancer diagnosis do so despite a very low risk of facing cancer in the healthy breast, new research from the University of Michigan Comprehensive Cancer Center finds.
NIH/National Cancer Institute

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 27-Nov-2012
Blood
Scripps Research Institute study points to potential new therapies for cancer and other diseases
Researchers at the Scripps Research Institute are fueling the future of cancer treatment by improving a powerful tool in disease defense: the body's immune system. By revealing a novel but widespread cell signaling process, the scientists may have found a way to manipulate an important component of the immune system into more effectively fighting disease.
National Institutes of Health, Leukemia and Lymphoma Society, Deutsche Forschungsgemeinschaft

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

Public Release: 27-Nov-2012
2012 Quality Care Symposium
Research from ASCO'S Quality Care Symposium shows advances and challenges in improving the quality of cancer care
New studies released today reveal important advances in cancer care quality measurement, physician adherence to quality standards, and end-of-life care, while highlighting the overuse of contralateral prophylactic mastectomy. The studies were released in a presscast today in advance of ASCO's inaugural 2012 Quality Care Symposium. The Symposium will take place Nov. 30 – Dec. 1, 2012, at the Manchester Grand Hyatt in San Diego.

Contact: Aaron Tallent
Aaron.Tallent@asco.org
571-483-1371
American Society of Clinical Oncology

Public Release: 27-Nov-2012
Nature Structural & Molecular Biology
New mechanism for cancer progression discovered by UNC and Harvard researchers
University of North Carolina Lineberger Comprehensive Cancer Center and Harvard researchers have discovered an alternative mechanism for activating rhe oncogene Ras that does not require mutation or hormonal stimulus.
National Institutes of Health, Japanese Society for the Promotion of Science Research, Kanae Foundation for Research Abroad

Contact: William Davis
william_davis@med.unc.edu
919-962-3405
University of North Carolina Health Care

Public Release: 27-Nov-2012
Cell
Research reveals new understanding of X chromosome inactivation
In a paper published in the Nov. 21 issue of Cell, a team led by Mauro Calabrese, a postdoctoral fellow at the University of North Carolina in the lab of Terry Magnuson, chair of the department of genetics and member of the UNC Lineberger Comprehensive Cancer Center, broadens the understanding of how cells regulate silencing of the X chromosome in a process known as X-inactivation.

Contact: William Davis
william_davis@med.unc.edu
919-962-3405
University of North Carolina Health Care

Public Release: 26-Nov-2012
Proceedings of the National Academy of Sciences
New hope for setback-dogged cancer treatment
Several drugs companies have ineffectively tried to produce antibodies that bind to the IGF-1 receptor on the cell surface, which has a critical part to play in the development of cancer. Scientists at Karolinska Institutet in Sweden have now ascertained how these antibodies work, and can explain why only some cancer patients are helped by IGF-1 blockers during clinical tests. The researchers also present a means by which drugs of this kind could help more cancer patients.
Swedish Cancer Society, Swedish Research Council, and others

Contact: Press Office
pressinfo@ki.se
46-852-486-077
Karolinska Institutet

Public Release: 26-Nov-2012
Journal of Clinical Investigation
JCI early table of contents for Nov. 26, 2012
This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published on Monday, November 26, 2012, in the JCI: Bariatric surgery procedures have similar therapeutic benefits in obese adults; Identifying the cause of anesthesia-induced seizures; Parallel structure: Surprising similarities between kidney cells and neurons; Mutations in αKlotho underlie a genetic form of rickets; and many more.

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 26-Nov-2012
Oncogene
Possible new treatment for Ewing sarcoma
Discovery of a new drug with high potential to treat Ewing sarcoma, an often deadly cancer of children and young adults, and the previously unknown mechanism behind it, come hand-in-hand in a new study by researchers from Huntsman Cancer Institute at the University of Utah. The report appears in today's online issue of the journal Oncogene.
NIH/National Cancer Institute, National Institutes of Health, Howard Hughes Medical Institute

Contact: Linda Aagard
801-587-7639
University of Utah Health Sciences

Public Release: 26-Nov-2012
Nature Cell Biology
Metabolic protein launches sugar feast that nurtures brain tumors
Researchers at the University of Texas MD Anderson Cancer Center have tracked down a cancer-promoting protein's pathway into the cell nucleus and discovered how, once there, it fires up a glucose metabolism pathway on which brain tumors thrive.

Contact: Scott Merville
smerville@mdanderson.org
713-792-0661
University of Texas M. D. Anderson Cancer Center

Public Release: 25-Nov-2012
Nature Medicine
Patient's own immune cells may blunt viral therapy for brain cancer
Doctors now use cancer-killing viruses to treat some patients with lethal, fast-growing brain tumors. Clinical trials show that these therapeutic viruses are safe but less effective than expected. A new study shows that the patient's own immune system quickly works to eliminate the anticancer virus, and it discovered how this happens.
NIH/National Cancer Institute, NIH/National Institute of Neurological Disorders and Stroke

Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Medical Center

Showing releases 26-50 out of 1136.

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