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Showing releases 26-50 out of 1244.

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Public Release: 16-Dec-2014
JAMA
Effectiveness of drugs to prevent hepatitis among patients receiving chemotherapy
Among patients with lymphoma undergoing a certain type of chemotherapy, receiving the antiviral drug entecavir resulted in a lower incidence of hepatitis B virus (HBV)-related hepatitis and HBV reactivation, compared with the antiviral drug lamivudine, according to a study in the Dec. 17 issue of JAMA.

Contact: Tongyu Lin
tongyulin@hotmail.com
The JAMA Network Journals

Public Release: 16-Dec-2014
Gastrointestinal Endoscopy
Mayo Clinic physicians say high-definition scopes accurately assess polyps
It may not be necessary for experienced gastroenterologists to send polyps they remove from a patient's colon to a pathologist for examination, according to a large study conducted by physician researchers at the Jacksonville campus of Mayo Clinic.
Olympus Corporation of America

Contact: Kevin Punsky
punsky.kevin@mayo.edu
904-953-0746
Mayo Clinic

Public Release: 16-Dec-2014
Nature Communications
New technology directly reprograms skin fibroblasts for a new role
Scientists have discovered a way to repurpose fibroblasts into functional melanocytes, the body's pigment-producing cells. The technique has immediate and important implications for developing new cell-based treatments for skin diseases such as vitiligo, as well as new screening strategies for melanoma.
National Institutes of Health

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Public Release: 16-Dec-2014
Review of Scientific Instruments
Microwave imaging of the breast
Although currently available diagnostic screening systems for breast are effective at detecting early signs of tumors, they are far from perfect, subjecting patients to ionizing radiation and sometimes inflicting discomfort on women who are undergoing screening because of the compression of the breast that is required to produce diagnostically useful images. New research suggests a better, cheaper, and safer way to look for the telltale signs of breast cancer may be with microwaves.

Contact: Jason Socrates Bardi
jbardi@aip.org
240-535-4954
American Institute of Physics

Public Release: 16-Dec-2014
British Journal of General Practice
Study recommends GPs should be more open when referring patients for cancer investigations
GPs should consider a more overt discussion with patients when referring them for further investigation of symptoms which may indicate cancer, according to a paper published in the British Journal of General Practice.
National Institute for Health Research

Contact: Philippa Walker
philippa.walker@bristol.ac.uk
44-117-928-8086
University of Bristol

Public Release: 16-Dec-2014
Genome Biology
Combining images and genetic data proves gene loss behind aggressive ovarian cancers
Cancer Research UK scientists have shown that loss of a gene called PTEN triggers some cases of an aggressive form of ovarian cancer, called high-grade serous ovarian cancer.
Cancer Research UK

Contact: Simon Shears
simon.shears@cancer.org.uk
Cancer Research UK

Public Release: 15-Dec-2014
Proceedings of the National Academy of Sciences
Too much, too little, just right
Scientists have long known the p53 protein suppresses tumors. However, a recent animal study by UC Davis researchers has uncovered a complicated relationship between p53 and another protein, Rbm38, highlighting how the body calibrates protein levels.
National Institutes of Health

Contact: Dorsey Griffith
dorsey.griffith@ucdmc.ucdavis.edu
916-734-9118
University of California - Davis Health System

Public Release: 15-Dec-2014
BBA Molecular Cell Research
If cells can't move ... cancer can't grow
By blocking a widespread enzyme, Centenary researchers have shown they can slow down the movement of cells and potentially stop tumors from spreading and growing.
Rebecca L. Cooper Medical Research Foundation, Australian Government, University of Sydney, Cancer Institute NSW, Perpetual Trustees, Clive and Vera Ramaciotti Foundation

Contact: Toni Stevens
toni@scienceinpublic.com.au
61-401-763-130
Centenary Institute

Public Release: 15-Dec-2014
JAMA Internal Medicine
Injuries from indoor tanning include burns, passing out, eye injuries
Skin burns, passing out and eye injuries were among the primary injuries incurred at indoor tanning sites and treated in emergency departments at US hospitals, according to a research letter published online by JAMA Internal Medicine.

Contact: Brittany Behm
media@cdc.gov
404-639-3286
The JAMA Network Journals

Public Release: 15-Dec-2014
Nature Materials
Molecular 'hats' allow in vivo activation of disguised signaling peptides
When someone you know is wearing an unfamiliar hat, you might not recognize them. Georgia Institute of Technology researchers are using just such a disguise to sneak biomaterials containing peptide signaling molecules into living animals.
National Science Foundation, National Institutes of Health

Contact: John Toon
jtoon@gatech.edu
404-894-6986
Georgia Institute of Technology

Public Release: 15-Dec-2014
Nature Nanotechnology
Promising new method for rapidly screening cancer drugs
Traditional genomic, proteomic and other screening methods currently used to characterize drug mechanisms are time-consuming and require special equipment, but now researchers led by chemist Vincent Rotello at the University of Massachusetts Amherst offer a multi-channel sensor method using gold nanoparticles that can accurately profile various anti-cancer drugs and their mechanisms in minutes.
NIH/Institute for General Medical Sciences, National Science Foundation's Center for Hierarchical Manufacturing at UMass Amherst.

Contact: Janet Lathrop
jlathrop@admin.umass.edu
413-545-0444
University of Massachusetts at Amherst

Public Release: 15-Dec-2014
Nature Genetics
Algorithm identifies networks of genetic changes across cancers
Using a computer algorithm that can sift through mounds of genetic data, researchers from Brown University have identified several networks of genes that, when hit by a mutation, could play a role in the development of multiple types of cancer. The researchers hope the new genetic insights might aid in the development of new drugs and treatment approaches for cancer.
National Science Foundation, National Institutes of Health

Contact: Kevin Stacey
kevin_stacey@brown.edu
401-863-3766
Brown University

Public Release: 15-Dec-2014
Nature Communications
Signaling mechanism could be target for survival, growth of tumor cells in brain cancer
UT Southwestern Medical Center neurology researchers have identified an important cell signaling mechanism that plays an important role in brain cancer and may provide a new therapeutic target.
National Institutes of Health, US Department of Veterans Affairs, William and Sylvia Zale Foundation, Ethel Silvergold Philanthropic Fund of the Dallas Jewish Community Foundation, Barbara F. Glick

Contact: Russell Rian
russell.rian@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center

Public Release: 15-Dec-2014
Journal of Health Psychology
People with low numeracy feel negative about taking part in bowel cancer screening
People who have problems with numbers may be more likely to feel negative about bowel cancer screening.
Cancer Research UK; NIH/National Institute for Health Research, Medical Research Council

Contact: Liz Smith
liz.smith@cancer.org.uk
020-346-98300
Cancer Research UK

Public Release: 15-Dec-2014
Nature
Joslin discovery may hold clues to treatments that slow aging
In a study published today by Nature, researchers at Joslin Diabetes Center used a microscopic worm, C. elegans, to identify a new path that could lead to drugs to slow aging and the chronic diseases that often accompany it -- and might even lead to better cosmetics.
National Institutes of Health

Contact: Jeffrey Bright
jeff.bright@joslin.harvard.edu
Joslin Diabetes Center

Public Release: 15-Dec-2014
eLife
Proteins drive cancer cells to change states
A new study from the Massachusetts Institute of Technology implicates a family of RNA-binding proteins in the regulation of cancer, particularly in a subtype of breast cancer.
National Institutes of Health

Contact: Sarah McDonnell
s_mcd@mit.edu
617-253-8923
Massachusetts Institute of Technology

Public Release: 15-Dec-2014
Journal of American Chemical Society
Dartmouth researchers create 'green' process to reduce molecular switching waste
Dartmouth researchers have found a solution using visible light to reduce waste produced in chemically activated molecular switches, opening the way for industrial applications of nanotechnology ranging from anti-cancer drug delivery to LCD displays and molecular motors.

Contact: John Cramer
John.Cramer@Dartmouth.edu
603-646-9130
Dartmouth College

Public Release: 15-Dec-2014
Pediatrics
E-cigarettes may recruit lower risk teens to nicotine use
A new study finds that one-third of Hawaiian adolescents have tried e-cigarettes, half of whom have never used another tobacco product. This is markedly higher rate than in the continental US. This raises the possibility that e-cigarettes are recruiting lower risk adolescents, who otherwise would be less susceptible to tobacco product use.
NIH/National Cancer Institute

Contact: Kirk Cassels
kirk.A.Cassels@Hitchcock.org
603-653-6177
The Geisel School of Medicine at Dartmouth

Public Release: 15-Dec-2014
Gynecologic Oncology
UTMB study finds that Hispanic women less likely to survive endometrial uterine cancer
In the largest study to date evaluating outcomes of Hispanic women with endometrial uterine cancer, researchers at the University of Texas Medical Branch at Galveston have found that Hispanic women in the United States were significantly less likely to survive the cancer than non-Hispanic white women. The study is available online in the December issue of Gynecologic Oncology.

Contact: Molly Dannenmaier
mjdannen@utmb.edu
409-772-8790
University of Texas Medical Branch at Galveston

Public Release: 15-Dec-2014
Journal of Clinical Oncology
Herceptin found to improve long-term survival of HER2-positive breast cancer patients
VCU Massey Cancer Center physician-researcher Charles E. Geyer, Jr., M.D., was the National Protocol Officer for one component of a large national study involving two National Cancer Institute-supported clinical trials that demonstrated that trastuzumab significantly improves the long-term survival of HER-2 positive breast cancer patients.
National Institutes of Health, National Surgical Adjuvant Breast and Bowel Project, Breast Cancer Research Foundation, Genentech

Contact: John Wallace
wallacej@vcu.edu
804-628-1550
Virginia Commonwealth University

Public Release: 15-Dec-2014
Proceedings of the National Academy of Sciences
Long noncoding RNAs: A novel prognostic marker in older patients with acute leukemia
A new study shows that patterns of molecules called long noncoding RNAs might help doctors choose the least toxic, most effective treatment for many older patients with acute myeloid leukemia. AML occurs mainly in older patients and has a three-year survival rate of 5 to 15 percent.
NIH/National Cancer Institute, Brigham and Women's Hospital, Coleman Leukemia Research Foundation, Pelotonia Fellowship Program, Associazione Italiana Ricerca sul Cancro AIRC, Ministero della Istruzione Università e Ricerca

Contact: Darrell E. Ward
darrell.ward@osumc.edu
614-293-3737
Ohio State University Wexner Medical Center

Public Release: 15-Dec-2014
Personality and Social Psychology Bulletin
War metaphors for cancer hurt certain prevention behaviors
It's not unusual for people to use war metaphors such as 'fight' and 'battle' when trying to motivate patients with cancer.

Contact: Jared Wadley
jwadley@umich.edu
734-936-7819
University of Michigan

Public Release: 15-Dec-2014
Biomedical Optics Express
Potential new tool for cervical cancer detection and diagnosis
A team of researchers from Central South University in China have demonstrated that a technique known as photoacoustic imaging, which is already under investigation for detecting skin or breast cancers and for monitoring therapy, also has the potential to be a new, faster, cheaper and noninvasive method to detect, diagnose and stage cervical cancer with high accuracy. Their work appears in a new paper in the Optical Society journal Biomedical Optics Express.

Contact: Jason Socrates Bardi
jbardi@aip.org
240-535-4954
The Optical Society

Public Release: 15-Dec-2014
2014 San Antonio Breast Cancer Symposium
Research: Two drugs before surgery help women with triple-negative breast cancer
A breast cancer specialist and clinical researcher at Women & Infants Hospital of Rhode Island presented research yesterday at the 2014 San Antonio Breast Cancer Symposium showing that adding either the chemotherapy drug carboplatin or the blood vessel-targeting drug bevacizumab to the standard treatment of chemotherapy before surgery helped women who have the basal-like subtype of triple-negative breast cancer.

Contact: Susan McDonald
slmcdonald@wihri.org
401-681-2816
Women & Infants Hospital

Public Release: 15-Dec-2014
Genetic Testing and Molecular Biomarkers
New colorectal cancer risk factor identified
Adiponectin, a collagen-like protein secreted by fat cells, derives from the ADIPOQ gene. Variations in this gene may increase risk for type 2 diabetes, cardiovascular disease, and various cancers. A new study that links specific variations in the ADIPOQ gene to either higher or lower colorectal cancer risk is published in Genetic Testing and Molecular Biomarkers.

Contact: Kathryn Ryan
kryan@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News

Showing releases 26-50 out of 1244.

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