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Showing releases 251-275 out of 1212. << < 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 > >>
Public Release: 20-Jun-2013
Berkeley Lab confirms thirdhand smoke causes DNA damage A study led by researchers from Lawrence Berkeley National Laboratory has found for the first time that thirdhand smoke -- the noxious residue that clings to virtually all surfaces long after the secondhand smoke from a cigarette has cleared out -- causes significant genetic damage in human cells. Contact: Julie Chao Public Release: 20-Jun-2013
Pluripotent cells from pancreatic cancer cells first human model of cancer's progression Pancreatic cancer carries a dismal prognosis. Researchers and clinicians don't have a non-invasive way to even detect early cells that portent later disease. Scientists have created a research cell line from a patient with advanced pancreatic cancer. This first-of-its-kind human-cell model of pancreatic cancer progression is the first example using induced pluripotent stem cells to model cancer progression directly from a solid tumor and to model pancreatic cancer from early to invasive stages. Contact: Karen Kreeger Public Release: 20-Jun-2013
Men who can't produce sperm face increased cancer risk, Stanford-led study finds Men who are diagnosed as azoospermic -- infertile because of an absence of sperm in their ejaculate -- are more prone to developing cancer than the general population, a study led by a Stanford University School of Medicine urologist has found. And a diagnosis of azoospermia before age 30 carries an eight-fold cancer risk, the study says. Contact: Bruce Goldman Public Release: 20-Jun-2013
Herding cancer cells to their death Publishing their findings in today's online issue of Cancer Cell, an international team of scientists led jointly by Professors Colin Goding from the Ludwig Institute for Cancer Research who is based at the University of Oxford and José Neptuno Rodriguez-López from the University of Murcia describe a therapeutic strategy that manipulates a mechanism driving cellular heterogeneity to treat advanced melanoma. Contact: Rachel Steinhardt Public Release: 20-Jun-2013
Virus combination effective against deadly brain tumor, Moffitt Cancer Center study shows A combination of the myxoma virus and the immune suppressant rapamycin can kill glioblastoma multiforme, the most common and deadliest malignant brain tumor, according to Moffitt Cancer Center research. Peter A. Forsyth, M.D., of Moffitt's Neuro-Oncology Program, says the combination has been shown to infect and kill both brain cancer stem cells and differentiated compartments of glioblastoma multiforme. Contact: Kim Polacek Public Release: 19-Jun-2013
Biologists identify the chemical behind cancer resistance in naked mole rats Two researchers at the University of Rochester have discovered the chemical that makes naked mole rats cancer-proof. Contact: Peter Iglinski Public Release: 19-Jun-2013
Scientists find new source of versatility so 'floppy' proteins can get things done Many proteins work like Swiss Army knives, fitting multiple functions into their elaborately folded structures. A bit mysteriously, some proteins manage to multitask even with structures that are unfolded and floppy -- "intrinsically disordered." In this week's issue of Nature, scientists at The Scripps Research Institute report their discovery of an important trick that a well-known intrinsically disordered protein uses to expand and control its functionality. Contact: Mika Ono Public Release: 19-Jun-2013
Moffitt Cancer Center researchers identify genetic variants predicting aggressive prostate cancers Researchers at Moffitt Cancer Center and colleagues at Louisiana State University have developed a method for identifying aggressive prostate cancers that require immediate therapy. It relies on understanding the genetic interaction between single nucleotide polymorphisms. The goal is to better predict a prostate cancer's aggressiveness to avoid unnecessary radical treatment. Contact: Kim Polacek Public Release: 19-Jun-2013
Genetics of cervical cancer raise concern about antiviral therapy in some cases A new understanding of the genetic process that can lead to cervical cancer may help improve diagnosis of potentially dangerous lesions for some women, and also raises a warning flag about the use of anti-viral therapies in certain cases -- suggesting they could actually trigger the cancer they are trying to cure. Contact: Andrey Morgun Public Release: 19-Jun-2013
Ibrutinib continues strong showing against mantle cell lymphoma In a major international study led by researchers at the University of Texas MD Anderson Cancer Center, the targeted therapy ibrutinib continues to show remarkable promise for the treatment of relapsed or refractory mantle cell lymphoma. Contact: Laura Sussman Public Release: 19-Jun-2013
Drug shows surprising efficacy as treatment for chronic leukemia, mantle cell lymphoma Two clinical studies published online in the New England Journal of Medicine suggest that the novel, targeted agent ibrutinib shows real potential is a safe, effective, treatment for adults with chronic lymphocytic leukemia and for patients with mantle cell lymphoma. Contact: Liz Bryan Public Release: 18-Jun-2013
Study shows how the Nanog protein promotes growth of head and neck cancer Researchers have identified a biochemical pathway in cancer stem cells that is essential for promoting head and neck cancer. The study shows that a protein called Nanog, which is normally active in embryonic stem cells, promotes the growth of cancer stem cells in head and neck cancer. The findings provide information essential for designing novel targeted drugs that might improve the treatment of head and neck cancer. Contact: Darrell E. Ward Public Release: 18-Jun-2013
Fat cells in breast may connect social stress to triple-negative breast cancer Local chemical signals released by fat cells in the mammary gland appear to provide a crucial link between exposure to unrelenting social stressors early in life, and the subsequent development of aggressive breast cancer. Contact: John Easton Public Release: 18-Jun-2013
An article in 'Cell' reveals a new resistance mechanism to chemotherapy in breast and ovarian cancer The team led by Spanish National Cancer Research Centre researcher Óscar Fernández-Capetillo, head of the Genomic Instability Group, together with researchers from the National Cancer Institute in the US, have participated in a study that describes the causes that explain why tumors with BRCA1 and BRCA2 mutations stop responding to PARP inhibitor drugs. Contact: Press Office Public Release: 18-Jun-2013
Scientists catch EGFR passing a crucial message to cancer-promoting protein Researchers have discovered and mapped the signaling network between two previously unconnected proteins, exposing a link that, if broken, could cut off cancer cell growth at its starting point. Contact: Scott Merville Public Release: 18-Jun-2013
Chemical probe confirms that body makes its own rotten egg gas, H2S, to benefit health A new study confirms directly what scientists previously knew only indirectly -- that poisonous "rotten egg" gas hydrogen sulfide is generated by the body's blood vessel cells. Researchers made the confirmation by developing a chemical probe that lights up in reaction to rotten egg gas. The scientists observed the process in real-time through a microscope, said chemist Alexander Lippert, Southern Methodist University, Dallas. "This is going to open up many experiments for scientists," Lippert said. Contact: Margaret Allen Public Release: 18-Jun-2013
UT Dallas study suggests new approach to fight lung cancer Recent research has shown that cancer cells have a much different -- and more complex -- metabolism than normal cells. Now, scientists at the University of Texas at Dallas have found that exploiting these differences might provide a new strategy to combat lung cancer. Contact: Amanda Siegfried Public Release: 17-Jun-2013
Study identifies protein essential for normal heart function A study by researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences and the Department of Pharmacology at the University of California, San Diego, shows that a protein called MCL-1, which promotes cell survival, is essential for normal heart function. Contact: Debra Kain Public Release: 17-Jun-2013
New alternative to surgery lets doctors remove suspicious polyps, keep colon intact A UCLA team of surgeons and gastroenterologists has been performing a new, minimally invasive procedure to remove large and hard-to-reach polyps while keeping the colon intact. The procedure, which combines two minimally invasive techniques, has currently been performed at only a handful of medical centers in the United States. Contact: Rachel Champeau Public Release: 17-Jun-2013
Observation is safe, cost-saving in low-risk prostate cancer Dana-Farber researchers find many men with low-risk, localized prostate cancers can safely choose observation instead of undergoing immediate treatment and a have better quality of life while reducing health care costs. Contact: Teresa Herbert Public Release: 17-Jun-2013
Preventing eggs' death from chemotherapy Young women who have cancer treatment often lose their fertility because chemotherapy and radiation can damage or kill their immature ovarian eggs, called oocytes. Now, Northwestern Medicine® scientists have found the molecular pathway that can prevent the death of immature ovarian eggs due to chemotherapy, potentially preserving fertility and endocrine function. Scientists achieved this in mice by adding a currently approved chemotherapy drug, imatinib mesylate, to another chemotherapy drug cisplatin. Contact: Marla Paul Public Release: 17-Jun-2013
NIH scientists find promising biomarker for predicting HPV-related oropharynx cancer Researchers have found that antibodies against the human papillomavirus may help identify individuals who are at greatly increased risk of HPV-related cancer of the oropharynx, which is a portion of the throat that contains the tonsils. Contact: NCI Press Office Public Release: 17-Jun-2013
Aspirin may fight cancer by slowing DNA damage Aspirin is known to lower risk for some cancers, and a new study led by a UC San Francisco scientist points to a possible explanation, with the discovery that aspirin slows the accumulation of DNA mutations in abnormal cells in at least one pre-cancerous condition. Contact: Jeffrey Norris Public Release: 17-Jun-2013
OHSU review: Previous studies overstated evidence on Medtronic spinal fusion product An analysis by the Evidence-based Practice Center at Oregon Health & Science University has found that previously published clinical trial studies about a controversial bone growth product used in spinal surgeries overstated the product's effectiveness. Contact: Todd Murphy Public Release: 17-Jun-2013
A new target for cancer drug development Harvard Stem Cell Institute researchers have identified in the most aggressive forms of cancer a gene known to regulate embryonic stem cell self-renewal, beginning a creative search for a drug that can block its activity. Contact: B. D. Colen
Showing releases 251-275 out of 1212. << < 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 > >>
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