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Showing releases 251-275 out of 1239.

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Public Release: 11-Aug-2014
American Chemical Society 248th National Meeting & Exposition
Venom gets good buzz as potential cancer-fighter (video)
Bee, snake or scorpion venom could form the basis of a new generation of cancer-fighting drugs, scientists will report. They devised a method for targeting venom proteins specifically to malignant cells while sparing healthy ones, which reduces or eliminates side effects that the toxins would otherwise cause. Their study is part of the 248th National Meeting of the American Chemical Society. A brand-new video on the research is available at

Contact: Michael Bernstein
American Chemical Society

Public Release: 11-Aug-2014
Journal of Experimental Medicine
Tackling liver injury
Researchers uncover a new drug that spurs liver regeneration after surgery.
National Institutes of Health, National Natural Science Foundation of China, Guangxi Natural Science Foundation, Science & Technology Planning Project of Guangxi Province, Science &Technology Planning Project of Guilin City

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 11-Aug-2014
Developmental Cell
How breast cancer usurps the powers of mammary stem cells
During pregnancy, certain hormones trigger specialized mammary stem cells to create milk-producing cells essential to lactation. Scientists at the University of California, San Diego School of Medicine and Moores Cancer Center have found that mammary stem cells associated with the pregnant mammary gland are related to stem cells found in breast cancer.
National Institutes of Health, California Breast Cancer Research Program

Contact: Yadira Galindo
University of California - San Diego

Public Release: 11-Aug-2014
Cancer Cell
Stanford researchers uncover cancer-causing mechanism behind powerful human oncogene
A protein present at high levels in more than half of all human cancers drives cell growth by blocking the expression of just a handful of genes involved in DNA packaging and cell death, according to a new study by researchers at the Stanford University School of Medicine.

Contact: Krista Conger
Stanford University Medical Center

Public Release: 10-Aug-2014
Scientists unlock key to blood vessel formation
Scientists from the University of Leeds have discovered a gene that plays a vital role in blood vessel formation, research which adds to our knowledge of how early life develops.
British Heart Foundation, Wellcome Trust, Medical Research Council

Contact: Ben Jones
University of Leeds

Public Release: 8-Aug-2014
Journal of Virology
Editing HPV's genes to kill cervical cancer cells
Using the genome editing tool known as CRISPR, Duke University researchers were able to selectively silence two genes in human papilloma virus that are responsible for the growth and survival of cervical carcinoma cells. After silencing the two HPV genes, the cancer cell's normal self-destruct machinery went into action.
National Institutes of Health

Contact: Karl Bates
Duke University

Public Release: 7-Aug-2014
Cancer categories recast in largest-ever genomic study
New research partly led by UC San Francisco-affiliated scientists suggests that one in 10 cancer patients would be more accurately diagnosed if their tumors were defined by cellular and molecular criteria rather than by the tissues in which they originated, and that this information, in turn, could lead to more appropriate treatments.

Contact: Peter Farley
University of California - San Francisco

Public Release: 7-Aug-2014
Cell Reports
University of Minnesota research finds key piece to cancer cell survival puzzle
An international team led by Eric A. Hendrickson of the University of Minnesota and Duncan Baird of Cardiff University has solved a key mystery in cancer research: What allows some malignant cells to circumvent the normal process of cell death that occurs when chromosomes get too old to maintain themselves properly?

Contact: Stephanie Xenos
University of Minnesota

Public Release: 7-Aug-2014
Cancer Prevention Research
Gut microbiome analysis improved noninvasive colorectal cancer screening
Analysis of the gut microbiome more successfully distinguished healthy individuals from those with precancerous adenomatous polyps and those with invasive colorectal cancer compared with assessment of clinical risk factors and fecal occult blood testing, according to data published in Cancer Prevention Research, a journal of the American Association for Cancer Research.
National Institutes of Health

Contact: Jeremy Moore
American Association for Cancer Research

Public Release: 7-Aug-2014
Largest cancer genomic study proposes 'disruptive' new system to reclassify tumors
After analyzing more than 3,500 tumors on multiple technology platforms TCGA researchers say cancers are more likely to be similar based on their cell type of origin as opposed to their tissue type of origin. The study suggests at least 10 percent of cancer patients would be classified differently under this protocol. But Buck faculty Christopher Benz thinks this fraction will swell when more samples and additional tumor types are included in the next analysis.
NIH/National Cancer Institute, NIH/National Human Genome Research Institute

Contact: Kris Rebillot
Buck Institute for Age Research

Public Release: 7-Aug-2014
Cancer study reveals powerful new system for classifying tumors
Cancers are classified primarily on the basis of where in the body the disease originates, as in lung cancer or breast cancer. According to a new study, however, one in 10 cancer patients would be classified differently using a new classification system based on molecular subtypes instead of the current tissue-of-origin system. This reclassification could lead to different therapeutic options for those patients.
National Institutes of Health

Contact: Tim Stephens
University of California - Santa Cruz

Public Release: 7-Aug-2014
Nature Communications
Mutations in a gene essential for cell regulation cause kidney cancer in children
Mutations in a gene that helps regulate when genes are switched on and off in cells have been found to cause rare cases of Wilms tumor, the most common kidney cancer occurring in children.
Wellcome Trust, Cancer Research UK

Contact: Henry French
Institute of Cancer Research

Public Release: 7-Aug-2014
Nature Cell Biology, Cell Cycle
A*Star scientists make breakthroughs in ovarian cancer research
Scientists at A*STAR's Institute of Medical Biology and the Bioinformatics Institute have found new clues to early detection and personalised treatment of ovarian cancer, currently one of the most difficult cancers to diagnose early due to the lack of symptoms that are unique to the illness.
Agency for Science, Technology and Research (A*STAR)

Contact: Vanessa Loh
Biomedical Sciences Institutes (BMSI)

Public Release: 7-Aug-2014
Cell Reports
Scientists uncover key piece to cancer cell survival puzzle
A chance meeting between two leading UK and US scientists could have finally helped solve a key mystery in cancer research. Professor Duncan Baird and his team from Cardiff University, working in collaboration with Eric A. Hendrickson from the University of Minnesota, have identified a specific gene that human cells require in order to survive chromosomal defects.

Contact: Chris Jones
Cardiff University

Public Release: 7-Aug-2014
Nature Communications
Cell mechanics may hold key to how cancer spreads and recurs
Cancer cells that break away from tumors to go looking for a new home may prefer to settle into a soft bed, according to new findings from researchers at the University of Illinois. Some particularly enterprising cancer cells can cause a cancer to spread to other organs or evade treatment to resurface after a patient is thought to be in remission. The researchers found that these tumor-repopulating cells may lurk quietly in stiffer cellular environments, but thrive in a softer space.
National Institutes of Health

Contact: Liz Ahlberg
University of Illinois at Urbana-Champaign

Public Release: 7-Aug-2014
Largest cancer genetic analysis reveals new way of classifying cancer
The work, led by researchers at the UNC Lineberger Comprehensive Cancer Center, UNC-Chapel Hill and other TCGA sites, revamps traditional ideas of how cancers are diagnosed and treated and could also have a profound impact on the future landscape of drug development.
NIH/National Cancer Institute, NIH/National Human Genome Research Institute

Contact: Katy Jones
University of North Carolina Health Care

Public Release: 7-Aug-2014
Pancreatic survival rates at standstill for 4 decades
Long-term survival from pancreatic cancer has failed to improve in 40 years -- with the outlook remaining the lowest of the 21 most common cancers, according to new figures published by Cancer Research UK.

Contact: Ailsa Stevens
Cancer Research UK

Public Release: 7-Aug-2014
Cell Reports
Scientists uncover stem cell behavior of human bowel for the first time
For the first time, scientists have uncovered new information on how stem cells in the human bowel behave, revealing vital clues about the earliest stages in bowel cancer development and how we may begin to prevent it.

Contact: Charli Scouller
Queen Mary, University of London

Public Release: 6-Aug-2014
Clinical Gastroenterology and Hepatology
Exposure to inflammatory bowel disease drugs could increase leukemia risk
Immunosuppressive drugs called thiopurines have been found to increase the risk of myeloid disorders, such as acute myeloid leukemia and myelodysplastic syndrome, a rare bone marrow disorder, seven-fold among inflammatory bowel disease patients.

Contact: Rachel Steigerwald
American Gastroenterological Association

Public Release: 6-Aug-2014
New England Journal of Medicine
Gene increases risk of breast cancer to 1 in 3 by age 70
Breast cancer risks for one of potentially the most important genes associated with breast cancer after the BRCA1/2 genes are today reported in the New England Journal of Medicine. Women with mutations in the PALB2 gene have on average a one in three chance of developing breast cancer by the age of 70.
European Research Council, Cancer Research UK

Contact: Craig Brierley
University of Cambridge

Public Release: 6-Aug-2014
Cell Transplantation
Researchers seek 'safety lock' against tumor growth after stem cell transplantation
Induced pluripotent stem cell-derived neural stem cells can promote functional recovery after spinal cord injury to laboratory animals; a drawback is their potential for tumorogenesis post-transplantation. To better understand this, researchers transplanted a human glioblastoma cell line into the intact spinal columns of laboratory mice that were either immunodeficient or immunocompetent, and treated with or without immunosuppressant drugs. They found that withdrawing immunosuppressant drugs eliminated tumor growth and created a 'safety lock' against tumor formation.
Japan Science and Technology, California Institute for Regenerative Medicine, Research Center Network for Realization of Regenerative Medicine, Centers for Clinical Application Research on Specific Disease/Organ

Contact: Robert Miranda
Cell Transplantation Center of Excellence for Aging and Brain Repair

Public Release: 6-Aug-2014
Cancer Research
Brain tumors fly under the body's radar like stealth jets, new U-M research suggests
Brain tumors fly under the radar of the body's defense forces by coating their cells with extra amounts of a specific protein, new research shows. Like a stealth fighter jet, the coating means the cells evade detection by the early-warning immune system that should detect and kill them. The stealth approach lets the tumors hide until it's too late for the body to defeat them.
NIH/National Institute of Neurological Disorders & Stroke

Contact: Kara Gavin
University of Michigan Health System

Public Release: 6-Aug-2014
A new way to model cancer
New gene-editing technique from researchers at MIT allows scientists to more rapidly study the role of mutations in tumor development.
National Institutes of Health, NIH/National Cancer Institute

Contact: Sarah McDonnell
Massachusetts Institute of Technology

Public Release: 6-Aug-2014
Proceedings of the National Academy of Sciences
Discovery yields master regulator of toxin production in staph infections
St. Jude Children's Research Hospital scientists have discovered an enzyme that regulates production of the toxins that contribute to potentially life-threatening Staphylococcus aureus infections. The study recently appeared in the scientific journal the Proceedings of the National Academy of Sciences. Researchers also showed that the same enzyme allows Staphylococcus aureus to use fatty acids acquired from the infected individual to make the membrane that bacteria need to grow and flourish.
National Institutes of Health, NIH/National Cancer Institute, American Lebanese Syrian Associated Charities

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Public Release: 6-Aug-2014
Optics Letters
New hand-held device uses lasers, sound waves for deeper melanoma imaging
Melanoma is the deadliest form of skin cancer, causing more than 75 percent of skin-cancer deaths. The thicker the melanoma tumor, the more likely it will spread and the deadlier it becomes. Now, a team of researchers from Washington University in St. Louis have developed a new hand-held device that uses lasers and sound waves that may change the way doctors treat and diagnose melanoma. The tool is ready for commercialization and clinical trials.

Contact: Lyndsay Meyer
The Optical Society

Showing releases 251-275 out of 1239.

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