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Showing releases 251-275 out of 1207.

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Public Release: 19-Apr-2013
The 2nd ESTRO Forum
Mathematical models out-perform doctors in predicting cancer patients' responses to treatment
Mathematical prediction models are better than doctors at predicting the outcomes and responses of lung cancer patients to treatment, according to new research presented on Saturday at the 2nd Forum of the European Society for Radiotherapy and Oncology. The presenter will say that she considers it unethical for treatment decisions to be based solely on doctors' opinions, when these models perform so much better.

Contact: Emma Mason
wordmason@mac.com
European Society for Radiotherapy and Oncology (ESTRO)

Public Release: 19-Apr-2013
2013 ARRS Annual Meeting
Tomosynthesis increases breast cancer detection rate
Two-dimensional plus 3-D breast imaging increases cancer detection rates by 11 percent, and could be particularly useful in detecting cancer in women with dense breasts, a new study suggests.

Contact: Samantha Schmidt
sschmidt@arrs.org
703-858-4316
American Roentgen Ray Society

Public Release: 19-Apr-2013
2013 ARRS Annual Meeting
Chemical shift MRI helps differentiate renal cell tumors more likely to metastasize
Adding "chemical shift" techniques to MRI can help differentiate clear cell renal cell carcinoma from other types of renal cell cancer, a new study shows. That differentiation can help physicians better determine treatment for these patients.

Contact: Samantha Schmidt
sschmidt@arrs.org
703-858-4316
American Roentgen Ray Society

Public Release: 19-Apr-2013
2013 ARRS Annual Meeting
2 views are better than 1 in 3-D breast screening
One-view 3-D breast screening (tomosynthesis) means less radiation dose and about five seconds less compression, but a study from Yale University, New Haven, Conn., found that obtaining both views is necessary to help ensure that a cancer won't be missed.

Contact: Samantha Schmidt
sschmidt@arrs.org
703-858-4316
American Roentgen Ray Society

Public Release: 18-Apr-2013
PLOS ONE
Identified as responsible for breast and ovarian hereditary cancer 3 mutations at BRCA1 gene
Researchers of the hereditary cancer research group at the Bellvitge Biomedical Research Institute and the Catalan Institute of Oncology conducted a functional and structural study of seven missense variants of the BRCA1 gene concluding that three of these variants are pathogenic, linked to the risk of suffering breast or ovarian cancer. The study has been published at PLoS One.
Instituto de Salud Carlos III, Generalitat de Catalunya and the Spanish Association Against Cancer

Contact: Arantxa Mena
comunicacio@idibell.cat
34-932-607-129
IDIBELL-Bellvitge Biomedical Research Institute

Public Release: 18-Apr-2013
2013 ARRS Annual Meeting
Screening breast ultrasound detects cancers missed on mammography in women with dense breasts
Screening breast ultrasound performed after mammography on women with greater than 50 percent breast density detects an additional 3.4 cancers or high risk lesions per one thousand woman screened, a detection rate just under that of screening mammography alone for women with less dense breasts, a new study shows. Screening mammography detects 4-5 cancers per thousand women screened.

Contact: Samantha Schmidt
sschmidt@arrs.org
703-858-4316
American Roentgen Ray Society

Public Release: 18-Apr-2013
2013 ARRS Annual Meeting
New ablation technique holds promise for liver cancer patients
A new minimally invasive tumor ablation technique is providing hope for liver cancer patients who can't undergo surgery or thermal ablation, a study shows.

Contact: Samantha Schmidt
sschmidt@arrs.org
703-858-4316
American Roentgen Ray Society

Public Release: 18-Apr-2013
American Journal of Human Genetics
Scientists find ethnicity linked to antibodies
Cracking the DNA code for a complex region of the human genome has helped 14 North American scientists, including five at Simon Fraser University, chart new territory in immunity research. They have discovered that a good number of our antibody genes and, potentially, what they fight off actually vary from person to person. After completely sequencing the immensely repetitive DNA in the human genome's immunoglobulin heavy-chain locus, they have also found ethnicity influences immunity.

Contact: Carol Thorbes
cthorbes@sfu.ca
778-782-3035
Simon Fraser University

Public Release: 18-Apr-2013
2013 ARRS Annual Meeting
Laser optics plus ultrasound imaging holds promise as a noninvasive test for prostate cancer
Multispectral photoacoustic imaging, which combines laser optics and ultrasound imaging technologies, can reliably distinguish between benign and malignant prostate tissue, a new study indicates.

Contact: Samantha Schmidt
sschmidt@arrs.org
703-858-4316
American Roentgen Ray Society

Public Release: 18-Apr-2013
Practical Radiation Oncology
New ASTRO white paper recommends best practices to improve safety and effectiveness of IGRT
The American Society for Radiation Oncology has issued a new white paper, "Assuring Safety and Quality in Image Guided Delivery of Radiation Therapy," that recommends best practices to improve the safety and effectiveness of image guided radiation therapy (IGRT), according to the manuscript published as an article in press online in Practical Radiation Oncology, the official clinical practice journal of ASTRO.

Contact: Michelle Kirkwood
press@astro.org
703-286-1600
American Society for Radiation Oncology

Public Release: 18-Apr-2013
Breast Cancer Research and Treatment
Cold winters freezing out breast cancer treatment
For women diagnosed with estrogen receptor positive breast cancer, tamoxifen is an essential drug used in treatment and prevention. Currently, tamoxifen is used in a one-size-fits-all approach where the same dose is prescribed for every patient. New research at Lawson Health Research Institute has found that in addition to patient-specific genetic factors, lack of exposure to vitamin D during the long winter months affects the body's ability to metabolize the drug.

Contact: Robert DeLaet
robert.delaet@lawsonresearch.com
519-685-8500 x75616
Lawson Health Research Institute

Public Release: 18-Apr-2013
Infection and Immunity
High-salt diet and ulcer bug combine to increase risk of cancer
Numerous epidemiologic studies have shown that a diet high in salt is associated with an increased risk of gastric cancer. Now Timothy L. Cover and colleagues of Vanderbilt University show that high dietary salt combined with infection by the ulcer-causing bacterium Helicobacter pylori greatly increases the risk of cancer.

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology

Public Release: 18-Apr-2013
Cancer Epidemiology, Biomarkers & Prevention
Smoking from hookah not a harmless alternative to cigarettes
Smoking tobacco through a hookah is a pastime gaining popularity among the college crowd, but many of them mistakenly believe that using the fragrant water pipe is less harmful than smoking cigarettes.

Contact: Jeffrey Norris
jeff.norris@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 17-Apr-2013
American Journal of Health Promotion
Some minorities believe they are less likely to get cancer compared to whites, Moffitt study shows
Researchers at Moffitt Cancer Center and colleagues analyzed national data to investigate the differences in cancer prevention beliefs by race and ethnicity. They found that minorities, including blacks, Asians and Hispanics, have differing beliefs about cancer prevention and feel they are less likely to get cancer than did whites. The researchers concluded that more culturally relevant information about cancer prevention and risk needs to reach minority populations.

Contact: Kim Polacek
kim.polacek@moffitt.org
813-745-7408
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 17-Apr-2013
Science Translational Medicine
DREAM and Sage Bionetworks tap the wisdom of the crowd to impact breast cancer prognosis
Two new reports issuing in Science Translational Medicine today showcase the potential of teams of scientists working together to solve increasingly complex medical problems. The results demonstrate that better predictors of breast cancer progression than those currently available can be rapidly evolved by running open Big Data Challenges such as The Sage Bionetworks/DREAM Breast Cancer Prognosis Challenge.
Avon Foundation For Women

Contact: Regina Warmoth
warmoth@sagebase.org
206-667-2102
Sage Bionetworks

Public Release: 17-Apr-2013
Nature
Fishing for solutions
Equipped with a high quality zebrafish genome, scientists have designed a method to assay the function of each and every gene and to explore the effects genetic variation has on zebrafish, giving other researchers the tools to understand human disease.

Contact: Aileen Sheehy
press.office@sanger.ac.uk
44-012-234-96928
Wellcome Trust Sanger Institute

Public Release: 17-Apr-2013
Proceedings of the National Academy of Sciences
Virus-like particles provide vital clues about brain tumors
Exosomes are small, virus-like particles that can transport genetic material and signal substances between cells. Researchers at Lund University, Sweden, have made new findings about exosomes released from aggressive brain tumors, gliomas. These exosomes are shown to have an important function in brain tumor development, and could be utilized as biomarkers to assess tumor aggressiveness through a blood test.

Contact: Mattias Belting
mattias.belting@med.lu.se
46-467-335-07473
Lund University

Public Release: 17-Apr-2013
Nature
Family ties: Relationship between human and zebrafish genomes
Researchers have developed a high-quality zebrafish genome to compare with the human reference genome and found that 84 percent of genes known to be associated with human disease have a zebrafish counterpart. This highlights the importance of zebrafish as a model organism for human disease research.

Contact: Aileen Sheehy
press.office@sanger.ac.uk
44-012-234-96928
Wellcome Trust Sanger Institute

Public Release: 17-Apr-2013
Scientific Reports
Recipe for large numbers of stem cells requires only one ingredient, says NIH/Pitt team
Stem cells and tissue-specific cells can be grown in abundance from mature mammalian cells simply by blocking a certain membrane protein, according to scientists at the University of Pittsburgh School of Medicine and the National Institutes of Health. Their experiments, reported today in Scientific Reports, also show that the process doesn't require other kinds of cells or agents to artificially support cell growth and doesn't activate cancer genes.
National Institutes of Health, and others

Contact: Anita Srikameswaran
SrikamAV@upmc.edu
412-578-9193
University of Pittsburgh Schools of the Health Sciences

Public Release: 17-Apr-2013
eLife
Reproductive tract secretions elicit ovulation
Eggs take a long time to produce in the ovary, and thus are one of a body's precious resources. It has been theorized that the body has mechanisms to help the ovary ensure that ovulated eggs enter the reproductive tract at the right time in order to maximize the chance of successful fertilization. New research from Carnegie's Allan Spradling and Jianjun Sun has shed light on how successful ovulation and fertilization are brought about by studying these processes in fruit flies.
Howard Hughes Medical Institute

Contact: Allan Spradling
spradling@ciwemb.edu
410-246-3015
Carnegie Institution

Public Release: 17-Apr-2013
PLOS ONE
Researchers abuzz over caffeine as cancer-cell killer
University of Alberta research team uses caffeine and fruit flies to pinpoint genetic pathways that guide DNA repair in cancer cells.

Contact: Bryan Alary
bryan.alary@ualberta.ca
780-492-0436
University of Alberta

Public Release: 17-Apr-2013
PLOS ONE
UGA research finds sterilized dogs live longer
Many dog owners have their pets spayed or neutered to help control the pet population, but new research from the University of Georgia suggests the procedure could add to the length of their lives and alter the risk of specific causes of death.

Contact: Kate E. Creevy
creevy@uga.edu
706-542-4622
University of Georgia

Public Release: 17-Apr-2013
Cancer Research
New drug combination therapy developed to treat leukemia
A new, pre-clinical study by researchers at Virginia Commonwealth University Massey Cancer Center suggests that a novel drug combination could lead to profound leukemia cell death by disrupting the function of two major pro-survival proteins. The effectiveness of the therapy lies in its ability to target a pro-survival cell signaling pathway known as PI3K/AKT/mTOR, upon which the leukemia cells have become dependent.
NIH/National Cancer Institute, National Institutes of Health

Contact: Alaina Farrish
akfarrish@vcu.edu
804-628-4578
Virginia Commonwealth University

Public Release: 17-Apr-2013
Cancer Epidemiology, Biomarkers & Prevention
Few breast cancer survivors maintain adequate physical activity despite benefits
Breast cancer survivors are among the women who could most benefit from regular physical activity, yet few meet national exercise recommendations during the 10 years after being diagnosed, according to a study by researchers at Fred Hutchinson Cancer Research Center.
National Institutes of Health

Contact: Dean Forbes
dforbes@gmail.com
206-667-2896
Fred Hutchinson Cancer Research Center

Public Release: 17-Apr-2013
Journal of Experimental Medicine
Molecule treats leukemia by preventing cancer cell repair, Jackson Laboratory scientists report
Researchers at The Jackson Laboratory have identified a molecule that prevents repair of some cancer cells, providing a potential new "genetic chemotherapy" approach to cancer treatment that could significantly reduce side effects and the development of treatment resistance compared with traditional chemotherapy.
NIH/National Cancer Institute

Contact: Joyce Peterson
joyce.peterson@jax.org
207-288-6058
Jackson Laboratory

Showing releases 251-275 out of 1207.

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