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Showing releases 276-300 out of 1312.

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Public Release: 16-Jul-2015
Preventive Medicine
Sitting time not associated with poorer diets in US adults
Previously identified associations between TV viewing and a less healthful diet may stem from exposure to advertisements of high calorie foods and 'distracted eating' rather than the activity of sitting itself

Contact: David Sampson
david.sampson@cancer.org
American Cancer Society

Public Release: 16-Jul-2015
JAMA Oncology
Exercising 300 minutes per week better for reducing total fat in postmenopausal women
Postmenopausal women who exercised 300 minutes per week were better at reducing total fat and other adiposity measures, especially obese women, during a one-year clinical trial, a noteworthy finding because body fat has been associated with increased risk of postmenopausal breast cancer, according to an article published online by JAMA Oncology.

Contact: Bruce Conway
bruce.conway@albertahealthservices.ca
403-943-1212
The JAMA Network Journals

Public Release: 16-Jul-2015
Cell
Scientists solve breast and ovarian cancer genetic mystery
Francis Crick Institute scientists, funded by Cancer Research UK, have solved a decades-old mystery and helped to unravel the genetic cause of some breast and ovarian cancers, according to new research published in the journal Cell.
Cancer Research UK

Contact: Greg Jones
greg.jones@cancer.org.uk
020-346-98311
Cancer Research UK

Public Release: 16-Jul-2015
Nature Communications
Can protein 14-3-3 sigma prevent or kill breast cancer tumors?
Every parent knows the maxim 'feed a cold, starve a fever.' In cancer, however, exactly how to feed or starve a tumor has not been easy to determine.

Contact: Ron Gilmore
rlgilmore1@mdanderson.org
713-745-1898
University of Texas M. D. Anderson Cancer Center

Public Release: 16-Jul-2015
JAMA Oncology
Increased radiation offers no survival benefit for patients with low-risk prostate cancer
Increased radiation dose is associated with higher survival rates in men with medium- and high-risk prostate cancer, but not men with low-risk prostate cancer, according to a new study from Penn Medicine published this week in JAMA Oncology.
NIH/National Cancer Institute

Contact: Steve Graff
stephen.graff@uphs.upenn.edu
215-349-5653
University of Pennsylvania School of Medicine

Public Release: 15-Jul-2015
ACS Nano
Magnetic nanoparticles could be key to effective immunotherapy
In recent years, researchers have hotly pursued immunotherapy, a promising form of treatment that relies on harnessing and training the body's own immune system to better fight cancer and infection. Now, results of a study led by Johns Hopkins investigators suggests that a device composed of a magnetic column paired with custom-made magnetic nanoparticles may hold a key to bringing immunotherapy into widespread and successful clinical use.
NIH/National Institute of Allergy and Infectious Diseases, NIH/National Institute of General Medical Sciences, NIH/National Cancer Institute, Troper Wojcicki Foundation, Virginia and D.K. Ludwig Fund for Cancer Research

Contact: Shawna Williams
shawna@jhmi.edu
410-955-8236
Johns Hopkins Medicine

Public Release: 15-Jul-2015
Cancer Epidemiology, Biomarkers & Prevention
Breast cancer survivors gain weight at a higher rate than their cancer-free peers
Breast cancer survivors with a family history of the disease, including those who carry BRCA1 and BRCA2 gene mutations, gained more weight over the course of four years than cancer-free women -- especially if they were treated with chemotherapy, according to a prospective study by Johns Hopkins Kimmel Cancer Center researchers.
Breast Cancer Research Foundation, NIH/National Cancer Institute

Contact: Valerie Mehl
mehlva@jhmi.edu
443-375-1991
Johns Hopkins Medicine

Public Release: 15-Jul-2015
13th International Conference on Malignant Lymphoma in Lugano
PET adapted treatment improves outcome of patients with stages I/II Hodgkin Lymphoma
Final results of the randomized intergroup EORTC, LYSA (Lymphoma Study Association), FIL (Fondazione Italiana Linfomi) H10 trial presented at the 13th International Conference on Malignant Lymphoma in Lugano, Switzerland, on 19 June 2015 show that early FDG-PET ( 2-deoxy-2[F-18]fluoro-D-glucose positron emission tomography) adapted treatment improves the outcome of early FDG-PET-positive patients with stages I/II Hodgkin lymphoma.

Contact: John Bean
john.bean@eortc.be
European Organisation for Research and Treatment of Cancer

Public Release: 15-Jul-2015
Cancer Epidemiology, Biomarkers & Prevention
Breast cancer survivors gain more weight than cancer-free women
Among women with a family history of breast cancer, those diagnosed with breast cancer gained weight at a greater rate compared with cancer-free women of the same age and menopausal status.
Breast Cancer Research Foundation, National Institutes of Health

Contact: Julia Gunther
julia.gunther@aacr.org
215-446-6896
American Association for Cancer Research

Public Release: 15-Jul-2015
Analytical Chemistry
A portable 'paper machine' can diagnose disease for less than $2
In the US and other industrialized nations, testing for infectious diseases and cancer often requires expensive equipment and highly trained specialists. In countries where resources are limited, performing the same diagnostics is far more challenging. To address this disparity, scientists are developing a portable, low-cost 'paper machine' for point-of-care detection of infectious diseases, genetic conditions and cancer. Their report appears in the ACS journal Analytical Chemistry.

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society

Public Release: 15-Jul-2015
Cancer Research
Compounds show potential in fighting brain and breast cancers
The University of Hawai'i Cancer Center researchers' discovery has potential to help brain and breast cancer patients.

Contact: Nana Ohkawa
nohkawa@cc.hawaii.edu
808-564-5911
University of Hawaii Cancer Center

Public Release: 15-Jul-2015
Nature Communications
Penn Vet team shows a protein modification determines enzyme's fate
Researchers from the University of Pennsylvania School of Veterinary Medicine show that an amino acid tag has the power to greatly influence the function of an enzyme called PRPS2, which is required for human life and can become hyperactive in cancer.
National Institutes of Health, Mari Lowe Center for Comparative Oncology

Contact: Katherine Unger Baillie
kbaillie@upenn.edu
215-898-9194
University of Pennsylvania

Public Release: 15-Jul-2015
Trends in Biochemical Sciences
Defective telomeres are now being linked to dozens of diseases, including many types of cancer
Studying telomeres, the structures that protect the ends of chromosomes, has become a key issue in biology. In recent years, not only has their relation to aging been confirmed; defective telomeres seem to be linked to more and more illnesses, including many types of cancer.

Contact: Nuria Noriega
comunicacion@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)

Public Release: 14-Jul-2015
Scientific Reports
New classification system for brain tumors
Despite modern chemoradiation therapy it is still very difficult to give reliable prognoses for malignant gliomas. Surgical removal of the glioma is still the preferred method of treatment. Doctors at Universitätsklinikum Erlangen's Department of Neurosurgery have now developed a new procedure for analyzing radiological imaging scans which makes it possible to predict the course of a disease relatively precisely. Their findings have now been published in the journal Scientific Reports.

Contact: Katrin Piecha
presse@fau.de
University of Erlangen-Nuremberg

Public Release: 14-Jul-2015
Journal of Clinical Oncology
Anti-stress hormone may provide indication of breast cancer risk
A new study from Lund University in Sweden shows that women with low levels of an anti-stress hormone have an increased risk of getting breast cancer. The study is the first of its kind on humans and confirms previous similar observations from animal experiments.
European Research Council, Swedish Research Council, Region Skåne

Contact: Olle Melander
Olle.Melander@med.lu.se
46-704-546-820
Lund University

Public Release: 14-Jul-2015
Advanced Materials
Nanospheres shield chemo drugs, safely release high doses in response to tumor secretions
Scientists coated nanospheres of the anti-cancer drug paclitaxel with a peptide shell that shields the drug as it travels through the circulatory system. When the nanosphere reaches a cancerous tumor, enzymes that enable metastasis slice open the shell to release the drug. The targeted delivery allowed them to safely give mice 16 times the maximum tolerated dose of the clinical formulation of paclitaxel and halted the growth of cancerous tumors.
NIH/National Institute of Biomedical Imaging and Bioengineering

Contact: Susan Brown
sdbrown@ucsd.edu
858-246-0161
University of California - San Diego

Public Release: 14-Jul-2015
Clinical Cancer Research
Dietary intervention primes triple-negative breast cancer for targeted therapy
A diet that starves triple-negative breast cancer cells of an essential nutrient primes the cancer cells to be more easily killed by a targeted antibody treatment, UW Carbone Cancer Center scientists report in a recent publication.

Contact: Susan Lampert Smith
SSmith5@uwhealth.org
608-890-5643
University of Wisconsin-Madison

Public Release: 13-Jul-2015
Gynecologic Oncology
Online registry improves clinical research study participation
Research for Her, Cedars-Sinai's groundbreaking online registry that matches women with research studies and clinical trials, enrolled study participants more quickly when compared with traditional paper-based registries, according to new research published in the journal Gynecologic Oncology.

Contact: Cara Martinez
cara.martinez@cshs.org
310-423-7798
Cedars-Sinai Medical Center

Public Release: 13-Jul-2015
Lancet Oncology
Liquid biopsy identifies mutations in colorectal cancer undetected in tissue biopsy
The CORRECT study, published ahead of print online today in The Lancet Oncology, is one of the largest trials to date comparing data provided by liquid versus tissue biopsy in metastatic colorectal cancer patients. According to the study, liquid biopsy (BEAMing technology) could become an essential tool for analyzing tumor genotypes in real time, and identifying significant mutations that occur during the course of disease and are not detected by tissue biopsy.

Contact: Amanda Wren
awren@vhio.net
34-695-207-886
Vall d'Hebron Institute of Oncology

Public Release: 13-Jul-2015
Cancer Epidemiology, Biomarkers & Prevention
Study links leisure time sitting to higher risk of specific cancers
Spending more leisure time sitting was associated with a higher risk of total cancer risk in women, and specifically with multiple myeloma, breast, and ovarian cancers, according a new study.
American Cancer Society

Contact: David Sampson
david.sampson@cancer.org
American Cancer Society

Public Release: 13-Jul-2015
Nature
New cell division mechanism discovered
Canadian and British researchers have discovered that chromosomes play an active role in animal cell division. This occurs at a precise stage -- cytokinesis -- when the cell splits into two new daughter cells.
Medical Research Council, Canadian Institutes of Health Research, Canada Foundation for Innovation, Fonds de Recherche du Québec-Santé, Cole Foundation, INCa, Cancer Research UK, Biotechnology and Biological Sciences Research Council

Contact: William Raillant-Clark
w.raillant-clark@umontreal.ca
514-343-7593
University of Montreal

Public Release: 13-Jul-2015
ACS Central Science
Cancer discovery links experimental vaccine and biological treatment
A new study at the University of Wisconsin-Madison has linked two seemingly unrelated cancer treatments that are both now being tested in clinical trials. One treatment is a vaccine that targets a structure on the outside of cancer cells, while the other is an altered enzyme that breaks apart RNA and causes the cell to commit suicide. The new understanding could help both approaches.

Contact: Ronald Raines
rtraines@wisc.edu
608-262-8588
University of Wisconsin-Madison

Public Release: 13-Jul-2015
19th International Conference on Prenatal Diagnosis and Therapy
JAMA
Noninvasive prenatal testing may also detect some maternal cancers
A study published today in the Journal of the American Medical Association shows that genetic test results, as revealed by non-invasive prenatal testing for fetal chromosome abnormalities, may detect underlying conditions in the mother, including cancer. The study reports on a case series of eight women who had abnormal noninvasive prenatal testing results. Their fetuses had normal chromosomes; retrospective genomic analysis showed the results were due to undiagnosed cancers in the mothers.
Illumina

Contact: Jeremy Lechan
jlechan@tuftsmedicalcenter.org
617-636-0104
Tufts Medical Center

Public Release: 13-Jul-2015
ACS Biomaterials Science & Engineering
Chemotherapeutic coatings enhance tumor-frying nanoparticles
In a move akin to adding chemical weapons to a firebomb, researchers at Duke University have devised a method to deposit a thin layer of hydrogels on the surface of nanoshells designed to absorb infrared light and generate heat to destroy tumors. When heated by the nanoshells, these special hydrogels lose their water content and any drugs trapped within, creating a formidable one-two punch.
National Institutes of Health

Contact: Ken Kingery
ken.kingery@duke.edu
919-660-8414
Duke University

Public Release: 13-Jul-2015
Gastrointestinal Endoscopy
Cancers caught during screening colonoscopy are more survivable
Patients whose colorectal cancer is detected during a screening colonoscopy are likely to survive longer than those who wait until they have symptoms before having the test.

Contact: Gina Steiner
gsteiner@asge.org
630-570-5635
American Society for Gastrointestinal Endoscopy

Showing releases 276-300 out of 1312.

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