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Showing releases 276-300 out of 1212. << < 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 > >>
Public Release: 17-Jun-2013
 Journal of the National Cancer InstituteTimeline reforms increase initiation speed of NCI sponsored clinical trials The National Cancer Institute and investigators have reduced the deadlines for initiation of trials with the goal of reaching more patients in need of new treatments, according to a study published June 17 in the Journal of the National Cancer Institute. Contact: Zachary Rathner
Public Release: 17-Jun-2013
Journal of Clinical InvestigationScouring the genome of adenoid cystic carcinoma In this issue of the Journal of Clinical Investigation, researchers led by Andrew Futreal at the Wellcome Trust Sanger Institute in Cambridge, MA, performed a type of genetic sequencing known as whole exome sequencing of 24 ACC cases. 
National Institutes of Health, Adenoid Cystic Carcinoma Research Foundation, Wellcome Trust
Contact: Jillian Hurst
Public Release: 17-Jun-2013
Journal of Clinical InvestigationJCI early table of contents for June 17, 2013 This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, June 17, 2013, in the JCI: Scouring the genome of adenoid cystic carcinoma; Variants in the SIM1 gene are associated with obesity; Vitamin B3 blocks cyst formation in a mouse model of polycystic kidney disease; and many more. Contact: Jillian Hurst
Public Release: 17-Jun-2013
ENDO 2013New medication treats drug-resistant prostate cancer in the laboratory A new drug called pyrvinium pamoate inhibits aggressive forms of prostate cancer that are resistant to standard drugs, according to a study conducted in an animal model. The results will be presented Monday at The Endocrine Society's 95th Annual Meeting in San Francisco. Contact: Aaron Lohr
Public Release: 17-Jun-2013
ENDO 2013Diabetics who use meters to monitor their glucose have better control over disease Mount Sinai researchers will demonstrate new data on diabetes self-management, as well as the role of prostastic acid phosphatase in Prostate Cancer bone metastases; identify new molecules that can stimulate the thyroid gland; reveal the prevalence of primary aldosteronism; and show how thyroid autoimmunity may be triggered by endoplasmic reticulum stress. Contact: Renatt Brodsky
Public Release: 17-Jun-2013
Biology of Blood and Marrow TransplantationCertain types of graft-versus-host disease may increase risk of death, Moffitt researcher says Joseph Pidala, M.D., M.S., assistant member of the Blood and Bone Marrow Transplant and Immunology programs at Moffitt Cancer Center, and colleagues from the Chronic Graft-Versus-Host Disease Consortium have determined that certain gastrointestinal and liver-related types of chronic graft-versus-host disease are associated with worsened quality of life and death.
NIH/National Cancer Institute
Contact: Kim Polacek
Public Release: 17-Jun-2013
Cancer DiscoveryAbnormalities in new molecular pathway may increase breast cancer risk A new molecular pathway involving the gene ZNF365 has been identified and abnormalities in that pathway may predict worse outcomes for patients with breast cancer, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research. Contact: Jeremy Moore
Public Release: 17-Jun-2013
ENDO 2013Exposure to low doses of BPA linked to increased risk of prostate cancer in human stem cells Exposing developing tissue to low levels of the plastic bisphenol A, commonly known as BPA, is linked to a greater incidence of prostate cancer in tissue grown from human prostate stem cells, a new study finds. The results will be presented Monday, June 17, at The Endocrine Society's 95th Annual Meeting in San Francisco. Contact: Jenni Glenn Gingery
Public Release: 17-Jun-2013
ENDO 2013Exposure to BPA in developing prostate increases risk of later cancer Early exposure to BPA (bisphenol A) -- an additive commonly found in plastic water bottles and soup can liners -- causes an increased cancer risk in an animal model of human prostate cancer, according to University of Illinois at Chicago researcher Gail Prins.
NIH/National Institute of Environmental Sciences
Contact: Sharon Parmet
Public Release: 16-Jun-2013
Nature Cell Biology'Chase and run' cell movement mechanism explains process of metastasis A mechanism that cells use to group together and move around the body -- called 'chase and run' -- has been described for the first time by scientists at UCL.
Medical Research Council, Wellcome Trust
Contact: Clare Ryan
Public Release: 15-Jun-2013
ENDO 2013Osteoporosis drug stops growth of breast cancer cells, even in resistant tumors A drug approved in Europe to treat osteoporosis has now been shown to stop the growth of breast cancer cells, even in cancers that have become resistant to current targeted therapies, according to a Duke Cancer Institute study.
Pfizer Pharmaceuticals
Contact: Rachel Harrison
Public Release: 15-Jun-2013
ENDO 2013Osteoporosis drug may help treat advanced hormone-sensitive breast cancer A new osteoporosis drug hinders the growth of estrogen-sensitive cancer that has become resistant to treatment with tamoxifen, a study in mice shows. Contact: Aaron Lohr
Public Release: 15-Jun-2013
ENDO 2013'Gene signature' test diagnoses benign thyroid growths A new genetic test accurately and consistently diagnoses benign growths, or nodules, on the thyroid gland, according to a study from Chile. Contact: Aaron Lohr
Public Release: 15-Jun-2013
ENDO 2013Source of tumor growth in aggressive prostate cancer found Researchers have discovered a molecular switch that explains, at least in part, how some fast-growing prostate cancers become resistant to hormone treatment, a new study conducted in human cell cultures and mice finds. The results were presented Saturday at The Endocrine Society's 95th Annual Meeting in San Francisco. Contact: Jenni Glenn Gingery
Public Release: 14-Jun-2013
Nature CommunicationsUsing math to kill cancer cells Nature Communications has published a paper from Ottawa researchers today, outlining how advanced mathematical modelling can be used in the fight against cancer. The technique predicts how different treatments and genetic modifications might allow cancer-killing, oncolytic viruses to overcome the natural defences that cancer cells use to stave off viral infection.
Canadian Institutes of Health Research, Terry Fox Foundation, Ontario Institute for Cancer Research, Cancer Research Society, Hecht Foundation/Canadian Cancer Society
Contact: Paddy Moore
Public Release: 14-Jun-2013
Cancer ResearchDevelopmental protein plays role in spread of cancer A protein used by embryo cells during early development, and recently found in many different types of cancer, apparently serves as a switch regulating the spread of cancer, known as metastasis, report researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center in the June 15, 2013 issue of the journal Cancer Research.
National Institutes of Health, California Institute of Regenerative Medicine, Blood Cancer Research Fund
Contact: Scott LaFee
Public Release: 14-Jun-2013
Proceedings of the National Academy of SciencesNew findings regarding DNA damage checkpoint mechanism in oxidative stress Researchers have uncovered a previously unknown surveillance mechanism, known as a DNA damage checkpoint, used by cells to monitor oxidatively damaged DNA. DNA repair takes place approximately 10,000 times per cell, per day, through processes that are still only partially understood because of their complexity, speed, and the difficulty of studying complex interactions within living cells.
National Institute of Health
Contact: James Hathaway
Public Release: 13-Jun-2013
Cancer DiscoveryGene variants may predict who will benefit from breast cancer prevention drugs In women at high risk for breast cancer, a long-term drug treatment can cut disease risk in half. Researchers have now identified two gene variants that may predict which women are most likely to benefit -- and which should avoid this therapy. There is nearly a six-fold difference in disease risk depending on which gene variants a woman carries. The work represents a major step toward truly individualized breast cancer prevention in high-risk women.
National Institutes of Health
Contact: Alisa Z Machalek
Public Release: 13-Jun-2013
Cancer CellProtein protects against breast cancer recurrence in animal model Precisely what causes breast cancer recurrence has been poorly understood. But now a piece of the puzzle has fallen into place: Researchers at the Perelman School of Medicine, University of Pennsylvania have identified a key molecular player in recurrent breast cancer -- a finding that suggests potential new therapeutic strategies.
NIH/National Cancer Institute, Department of Defense Breast Cancer Research Program, Breast Cancer Research Foundation
Contact: Karen Kreeger
Public Release: 13-Jun-2013
Cardiovascular ResearchGene offers an athlete's heart without the exercise Researchers at Case Western Reserve University have found that a single gene poses a double threat to disease: Not only does it inhibit the growth and spread of breast tumors, but it also makes hearts healthier. In 2012, medical school researchers discovered the suppressive effects of the gene HEXIM1 on breast cancer in mouse models. Now they have demonstrated that it also enhances the number and density of blood vessels in the heart.
National Institutes of Health, American Heart Association, American Recovery & Reinvestment Act
Contact: Jessica Studeny
Public Release: 13-Jun-2013
FrontiersFrontiers news briefs: June 13 In this week's news briefs: insights into harmful fungal communities in composts; why extroverts consistently seek out rewarding environments; the role of microRNAs in the tumorigenesis of ovarian cancer; and the epidemiology of criniviruses. Contact: Gozde Zorlu
Public Release: 13-Jun-2013
Journal of the American Veterinary Medical AssociationHelping pet owners make tough choices Perhaps the hardest part of owning a pet is making difficult decisions when a beloved companion becomes seriously ill. That's why Michigan State University researchers are developing a new tool to help people assess their ailing pets' quality of life, a key factor in decisions about when to order life-prolonging procedures and when an animal's suffering means it's time to let go. Contact: Andy McGlashen
Public Release: 13-Jun-2013
Proceedings of the National Academy of SciencesMetabolic molecule drives growth of aggressive brain cancer A new study has identified an abnormal metabolic pathway that drives cancer-cell growth in a particular subtype of glioblastoma, the most common and lethal form of brain cancer. The finding could lead to new therapies for a subset of patients with glioblastoma.
NIH/National Cancer Institute, ACS, NIH/National Institute of General Medical Sciences
Contact: Darrell E. Ward
Public Release: 13-Jun-2013
Journal of Chromotography BMonell-led research identifies scent of melanoma Monell researchers identified odorants from human skin cells that can be used to identify melanoma, the deadliest form of skin cancer. In addition, a nanotechnology-based sensor could utilize the odor profiles to reliably differentiate melanoma cells from normal skin cells. Non-invasive odor analysis may be a valuable technique in the detection and early diagnosis of human melanoma.
NIH/National Institute on Deafness and Other Communication Disorders
Contact: Leslie Stein
Public Release: 13-Jun-2013
American Journal of Public HealthTobacco laws for youth may reduce adult smoking States that want to reduce rates of adult smoking may consider implementing stringent tobacco restrictions on teens. Washington University researchers discovered that states with more restrictive limits on teens purchasing tobacco also have lower adult smoking rates, especially among women.
NIH/National Cancer Institute, NIH/National Institute on Drug Abuse, American Cancer Society
Contact: Jim Dryden
Showing releases 276-300 out of 1212. << < 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 > >>
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