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Showing releases 301-325 out of 1332.

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Public Release: 23-Mar-2015
Journal of Cell Biology
Stress granules ease the way for cancer metastasis
Tumors that produce more stress granules are more likely to metastasize, according to researchers in Canada. The results suggest that drugs to inhibit the formation of these structures might rein in cancer metastasis.
Terry Fox Research Institute, Prostate Cancer Canada-Movember Foundation, German Research Foundation, British Columbia Cancer Foundation

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press

Public Release: 23-Mar-2015
American Chemical Society 249th National Meeting & Exposition
Popular artificial sweetener could lead to new treatments for aggressive cancers
Saccharin, the artificial sweetener that is the main ingredient in Sweet 'N Low, Sweet Twin and Necta, could do far more than just keep our waistlines trim. This popular sugar substitute could potentially lead to the development of drugs capable of combating aggressive, difficult-to-treat cancers with fewer side effects. They will present their work today at the 249th National Meeting & Exposition of the American Chemical Society.

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society

Public Release: 23-Mar-2015
BMC Medicine
Good news for serial cereal eaters
A diet high in whole grains and cereal fibers is associated with a reduced risk of premature death, according to research published in the open-access journal BMC Medicine. The results also show cereal fibers to be associated with reduced risk of deaths in varying degrees for chronic diseases including cancer, heart disease, respiratory disease and diabetes.

Contact: Shane Canning
shane.canning@biomedcentral.com
44-020-319-22243
BioMed Central

Public Release: 22-Mar-2015
American Chemical Society 249th National Meeting & Exposition
Vitamin D may keep low-grade prostate cancer from becoming aggressive
Taking vitamin D supplements could slow or even reverse the progression of less aggressive, or low-grade, prostate tumors without the need for surgery or radiation, a scientist will report today at the 249th National Meeting & Exposition of the American Chemical Society.

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society

Public Release: 22-Mar-2015
OncoImmunology
New potential for personalized treatments in bowel cancer
Scientists have found that genetic changes in bowel tumors are linked to the way the body's immune system responds to the cancer.
Cancer Research UK

Contact: Stephanie McClellan
stephanie.mcclellan@cancer.org.uk
44-203-469-5314
Cancer Research UK

Public Release: 20-Mar-2015
Nature Communications
Stinging nettle chemical improves cancer drug
A cancer drug could be made 50 times more effective by a chemical found in stinging nettles and ants, new research finds. Researchers at the University of Warwick found that when the chemical, Sodium Formate, is used in combination with a metal-based cancer treatment it can greatly increase its ability to shut down cancer cells.
European Research Council, Engineering and Physical Sciences Research Council, University of Warwick IAS, Science City

Contact: Tom Frew
a.t.frew@warwick.ac.uk
44-024-765-75910
University of Warwick

Public Release: 20-Mar-2015
Lancet Oncology
Measuring treatment response proves to be a powerful tool for guiding leukemia treatment
Measuring the concentration of leukemia cells in patient bone marrow during the first 46 days of chemotherapy should help boost survival of young leukemia patients by better matching patients with the right intensity of chemotherapy. St. Jude Children's Research Hospital investigators led the research, which appears in the March 20 edition of the journal Lancet Oncology.
National Institutes of Health, ALSAC

Contact: Summer Freeman
summer.freeman@stjude.org
901-595-3061
St. Jude Children's Research Hospital

Public Release: 20-Mar-2015
American Journal of Pathology
Researchers ID potential prognostic marker for recurrence of head and neck squamous cell carcinoma
A new study provides the first evidence that the mediator complex subunit 15 (MED15) may play a crucial role in the pathophysiology of head and neck squamous cell carcinoma (HNSCC). MED15 overexpression was found to be associated with higher mortality rates in HNSCC patients with cancer recurrence, particularly in oral cavity/oropharyngeal tumors, according to the study published in the American Journal of Pathology. MED15 overexpression was also associated with heavy alcohol consumption, which is an HNSCC risk factor.
German Research Foundation, Rudolf-Becker-Foundation, Medical Faculty of the University of Bonn, Gerok-Fellowship, and others

Contact: Eileen Leahy
ajpmedia@elsevier.com
732-238-3628
Elsevier Health Sciences

Public Release: 19-Mar-2015
16th World Conference on Tobacco or Health
New tobacco atlas details scale, harms of tobacco epidemic
The fifth edition of the Cancer Atlas graphically details the scale of the tobacco epidemic; the harmful influence of tobacco on health, poverty, social justice, and the environment; the progress being made in tobacco control; and the latest products and tactics being used by the industry to protect its profits and delay and derail tobacco control
American Cancer Society, World Lung Foundation

Contact: Raul Duany
raul.duany@cancer.org
American Cancer Society

Public Release: 19-Mar-2015
Biomaterials
Breast implants could become safer thanks to cell-friendly surface
Scientists at The University of Manchester have created an enhanced surface for silicone breast implants which could reduce complications and make them less likely to be rejected by the body.

Contact: Jamie Brown
Jamie.brown@manchester.ac.uk
44-016-127-58383
University of Manchester

Public Release: 19-Mar-2015
JAMA Otolaryngology -- Head & Neck Surgery
Effect of smoking, alcohol on feeding tube duration in head/neck cancer patients
Current smoking and heavy alcohol consumption appear to be risk factors for prolonged use of a feeding tube in patients with head and neck cancer undergoing radiotherapy or chemoradiotherapy, according to a report published online by JAMA Otolaryngology-Head & Neck Surgery.

Contact: Patrick Sheahan, M.B., M.D., F.R.C.S.I.
sheahan.patrick@sivuh.ie
The JAMA Network Journals

Public Release: 19-Mar-2015
PLOS Computational Biology
Cancer therapy 'tumor sanctuaries' and the breeding ground of resistance
Tumors acquiring resistance is one of the major barriers to successful cancer therapy. Feng Fu, Sebastian Bonhoeffer and their collaborator Martin Nowak use mathematical models to characterize how important aspects of tumor microenvironment can impair the efficacy of targeted cancer therapies.

Contact: Feng Fu
fufeng@gmail.com
41-446-329-303
PLOS

Public Release: 19-Mar-2015
JAMA Oncology
Racial, ethnic differences in picking surgeons, hospitals for breast cancer care
Black and Hispanic women with breast cancer were less likely to pick their surgeon and the hospital for treatment based on reputation compared with white women, suggesting minority patients may rely more on physician referrals and health plans in those decisions, according to a study published online by JAMA Oncology.

Contact: John Noble
johnw_noble@dfci.harvard.edu
617-632-5784
The JAMA Network Journals

Public Release: 19-Mar-2015
JAMA Oncology
Kidney cancer detected early with urine test
If kidney cancer is diagnosed early -- before it spreads beyond the kidney -- 80 percent of patients survive. However, finding it early has been among the disease's greatest challenges. Now, Washington University School of Medicine researchers have developed a noninvasive method to screen for kidney cancer that involves measuring the presence of proteins in the urine.
Barnes-Jewish Hospital Frontier Fund, Department of Anesthesiology at Washington University School of Medicine in St. Louis, Bear Cub Fund of Washington University, Barnes-Jewish Hospital Foundation

Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine

Public Release: 19-Mar-2015
British Journal of Cancer
Text message reminders boost breast cancer screening attendance
Women who received a text message reminding them about their breast cancer screening appointment were 20 percent more likely to attend than those who were not texted, according to a study published in the British Journal of Cancer today.

Contact: Emily Head
emily.head@cancer.org.uk
020-346-96189
Cancer Research UK

Public Release: 19-Mar-2015
Nature Biotechnology
Researchers in Berlin tweak the immune system to target cells bearing tumor antigens
Researchers at the Max Delbrück Center Berlin-Buch and Charité-Universitätsmedizin Berlin, Campus Berlin-Buch, have succeeded in generating cells of the immune system to specifically target and destroy cancer cells. The research findings have now been published in Nature Biotechnology online.
Deutsche Forschungsgemeinschaft, Berlin Institute of Health

Contact: Barbara Bachtler
bachtler@mdc-berlin.de
49-309-406-3896
Max Delbrueck Center for Molecular Medicine (MDC) Berlin-Buch

Public Release: 19-Mar-2015
Molecular Cancer Therapeutics
Bright new hope for beating deadly hereditary stomach and breast cancers
Deadly familial stomach and lobular breast cancers could be successfully treated at their earliest stages, or even prevented, by existing drugs that have been newly identified by cancer genetics researchers at New Zealand's University of Otago.
Health Research Council of New Zealand

Contact: Parry Guilford
parry.guilford@otago.ac.nz
University of Otago

Public Release: 19-Mar-2015
Nature Communications
Scientists trace genomic evolution of high-risk leukemia
By genomic sequencing of leukemia cells from relapsed patients at different stages, scientists have discovered key details of how acute lymphoblastic leukemia cells mutate to survive chemotherapy.
Pediatric Cancer Genome Project, NIH/National Cancer Institute, St. Baldrick's Foundation, ALSAC

Contact: Summer Freeman
summer.freeman@stjude.org
901-595-3061
St. Jude Children's Research Hospital

Public Release: 19-Mar-2015
Physician Leadership Journal
Streamlined 'military' work flow means more patient appointments and fewer return visits
Both patients and physicians may benefit from a 'work flow' system developed at military medical facilities and tested at a Johns Hopkins Kimmel Cancer Center clinic, according to results of an efficiency study.

Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medicine

Public Release: 19-Mar-2015
Nature
Strengthening the immune system's fight against brain cancer
When cancer strikes, it may be possible for patients to fight back with their own defenses, using a strategy known as immunotherapy. According to a new study published in Nature, researchers have found a way to enhance the effects of this therapeutic approach in glioblastoma, a deadly type of brain cancer, and possibly improve patient outcomes. The research was funded by the National Institutes of Health.
NIH/National Institute of Neurological Disorders and Stroke, NIH/National Cancer Institute

Contact: Barbara McMakin
nindspressteam@ninds.nih.gov
NIH/National Institute of Neurological Disorders and Stroke

Public Release: 19-Mar-2015
Oncotarget
World-first cancer drugs could work in larger group of patients
A pioneering class of drugs that target cancers with mutations in the BRCA breast cancer genes could also work against tumors with another type of genetic fault, a new study suggests. Scientists at The Institute of Cancer Research, London, found that errors in a gene called CLBC leave cancer cells vulnerable to PARP inhibitor drugs. Around 2 percent of all tumors have defects in CLBC.
European Union

Contact: Henry French
henry.french@icr.ac.uk
020-715-35582
Institute of Cancer Research

Public Release: 18-Mar-2015
Philosophical Transactions of the Royal Society B
Is too much artificial light at night making us sick?
Modern life, with its preponderance of inadequate exposure to natural light during the day and overexposure to artificial light at night, is not conducive to the body's natural sleep/wake cycle. UConn Health cancer epidemiologist Richard Stevens and co-author Yong Zhu from Yale University suggest such overexposure has possible ties to cancer, obesity, diabetes, and other health issues in an article published in the British journal Philosophical Transactions of the Royal Society B.

Contact: Chris DeFrancesco
cdefrancesco@uchc.edu
860-679-3914
University of Connecticut

Public Release: 18-Mar-2015
JAMA
Doctors say women with aytpia or DCIS should seek second opinions after breast biopsies
While doctors almost always agree on a pathological diagnosis of invasive breast cancer, there is room for improvement when diagnosing atypia (or atypical ductal hyperplasia-ADH) and DCIS (ductal carcinoma in-situ), Dartmouth researchers have found.
NIH/National Cancer Institute, NCI Breast Cancer Surveillance Consortium

Contact: Kirk Cassels
603-653-6177
The Geisel School of Medicine at Dartmouth

Public Release: 18-Mar-2015
Journal of Physical Chemistry
Buckyballs become bucky-bombs
Scientists have built nanoscale explosives out of buckyballs that could one day be used to eliminate cancer cells without damaging surrounding tissue.
São Paulo Research Foundation, Brazilian National Council for Scientific and Technological Development, US Department of Energy, Russian Science Foundation

Contact: Robert Perkins
perkinsr@usc.edu
213-740-9226
University of Southern California

Public Release: 18-Mar-2015
Journal of Health Disparities Research Practices
mHealth app ideal for breast cancer risk assessment, prevention
Interviewing women at a breast-imaging center in an urban safety net institution before and after they used a 'mHealth' mobile health app on a tablet, Dartmouth researchers concluded that older, diverse, and low income women found it easy to use and acceptable.
University of California at San Francisco Center for Aging in Diverse Communities, NIH/National Institute on Aging

Contact: Kirk Cassels
Kirk.A.Cassels@Hitchcock.org
603-653-6177
The Geisel School of Medicine at Dartmouth

Showing releases 301-325 out of 1332.

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