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Showing releases 301-325 out of 1201.

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Public Release: 11-Apr-2013
Report finds continuing challenges in changing behaviors that increase cancer risk
An annual report from the American Cancer Society finds continuing challenges in changing behaviors and risk factors in order to reduce suffering and death from cancer.
American Cancer Society

Contact: David Sampson
david.sampson@cancer.org
American Cancer Society

Public Release: 11-Apr-2013
Nature
Scientists map elusive 3-D structure of telomerase enzyme, key actor in cancer, aging
Like finally seeing the gears of a watch and how they work together, all components of an entire telomerase enzyme complex have been positioned into a three-dimensional structure for the first time. This first complete visual map of the telomerase enzyme complex, known to play a significant role in cancer and aging, is a breakthrough from UCLA and UC Berkeley biochemists.

Contact: Stuart Wolpert
swolpert@support.ucla.edu
310-206-0511
University of California - Los Angeles

Public Release: 11-Apr-2013
Journal of Biological Chemistry
LSUHSC research discovers new drug target for metastatic breast cancer
Research led by Dr. Suresh Alahari, Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, is the first to report that two specific tumor suppressor genes work in concert to inhibit the growth and spread of breast tumor cells to the lungs.
National Institutes of Health, Susan Komen Foundation, Louisiana Cancer Research Center

Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Sciences Center

Public Release: 11-Apr-2013
Acta Obstetricia et Gynecologica Scandinavica
Endometriosis treatments lower ovarian cancer risk
A novel study shows women who undergo surgical treatment for endometriosis have a lower risk of developing ovarian cancer. According to results published in Acta Obstetricia et Gynecologica Scandinavica, a journal of the Nordic Federation of Societies of Obstetrics and Gynecology, hormonal treatments for endometriosis did not lower ovarian cancer risk.

Contact: Dawn Peters
781-388-8408
Wiley

Public Release: 11-Apr-2013
AACR Annual Meeting 2013
Soy-based compound may reduce tumor cell proliferation in colorectal cancer
Research on a soy-based treatment for colorectal cancer, a promising agent in ovarian cancer, and a new drug target for advanced prostate cancer was presented at the American Association for Cancer Research 2013 Annual Meeting. The meeting took place April 6-10, 2013, in Washington, DC.

Contact: Mount Sinai Press Office
newsmedia@mssm.edu
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 11-Apr-2013
Proceedings of the National Academy of Sciences
A novel surface marker helps scientists 'fish out' mammary gland stem cells
In an advancement by the Hannon lab at CSHL, it is now possible to profile normal and cancerous mammary stem cells at an unprecedented high degree of purity. This may help identify genes that should be investigated as the next breast cancer drug targets.
National Institutes of Health

Contact: Peter Tarr
tarr@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory

Public Release: 10-Apr-2013
Science Translational Medicine
Signature of circulating breast tumor cells that spread to the brain found
Some breast tumor circulating cells in the bloodstream are marked by a constellation of biomarkers that identify them as those destined to seed the brain with a deadly spread of cancer, said researchers led by those at Baylor College of Medicine in a report that appears online in the journal Science Translational Medicine.

Contact: Glenna Picton
picton@bcm.edu
713-798-4710
Baylor College of Medicine

Public Release: 10-Apr-2013
American Chemical Society's 245th National Meeting & Exposition
GUMBOS technology promises new drugs, electronic devices
Mention a breakthrough involving "gumbo" technology, and people think of a new twist on the local dish, the stew that's the quintessence of southern Louisiana cooking. But scientific presentations at a meeting of the world's largest scientific society are focusing on what may be an advance in developing GUMBOS-based materials with far-reaching medical, electronic and other uses. Scientists reported on the materials at the 245th National Meeting & Exposition of the American Chemical Society.

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society

Public Release: 10-Apr-2013
AACR Annual Meeting 2013
Ludwig presents advancements in immunotherapy and epigenetics at the American Association for Cancer Research Annual Meeting
A dozen Ludwig scientists from around the world presented the latest advancements in basic and clinical cancer research at this week's American Association of Cancer Research Annual Meeting 2013. Progress in immunotherapy and epigenetics led the program with important diagnostic and treatment implications for emerging cancer therapy.

Contact: Rachel Steinhardt
rsteinhardt@licr.org
212-450-1582
Ludwig Institute for Cancer Research

Public Release: 10-Apr-2013
AACR Annual Meeting 2013
Fox Chase researchers find some lung cancers linked to common virus
A common virus known to cause cervical and head and neck cancers may also trigger some cases of lung cancer, according to new research presented by Fox Chase Cancer Center at the AACR Annual Meeting 2013 on Wednesday, April 10.

Contact: Diana Quattrone
diana.quattrone@fccc.edu
215-728-7784
Fox Chase Cancer Center

Public Release: 10-Apr-2013
AACR Annual Meeting 2013
AACR news: Studies show increasing evidence that androgen drives breast cancer
Estrogen and progesterone receptors, and the gene HER2 -- these are the big three markers and/or targets in breast cancer. Evidence presented at the AACR Annual Meeting 2013 adds a fourth: Androgen receptors.

Contact: Garth Sundem
garth.sundem@ucdenver.edu
805-559-2023
University of Colorado Denver

Public Release: 10-Apr-2013
Journal of Biological Chemistry
ALBA Synchrotron used for first time as a microscope to determine protein structure
A study led by the Universitat Autònoma de Barcelona has determined the three-dimensional structure of certain proteins linked to the correct functioning of the cell division process: The LC8 and Nek9 pair. This study, published in the Journal of Biological Chemistry, could have implications for research into diseases related to this process, such as cancer.

Contact: Octavi López Coronado
octavi.lopez@uab.cat
34-935-813-301
Universitat Autonoma de Barcelona

Public Release: 10-Apr-2013
Journal of Biological Chemistry
LSUHSC research reveals Rx target for HPV, Hep C and related cancers
New discoveries by a team of scientists at LSU Health Sciences Center New Orleans for the first time reveal the inner workings of a master regulator that controls functions as diverse as the ability of nerve cells to "rewire" themselves in response to external stimuli and the mechanism by which certain viruses hijack normal cellular processes to facilitate their replication that can ultimately lead to cancer.
National Institutes of Health

Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Sciences Center

Public Release: 10-Apr-2013
Molecular Cancer Therapeutics
Naturally-occurring substance proves effective against deadly skin cancer in laboratory tests
For the first time, scientists have demonstrated the mechanism of action of gossypin, a naturally-occurring substance found in fruits and vegetables, as a treatment for melanoma, which causes the majority of deaths from skin cancer.
Texas Biomedical Forum, Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation

Contact: Joseph Carey
jcarey@txbiomed.org
210-258-9437
Texas Biomedical Research Institute

Public Release: 10-Apr-2013
The Open Virology Journal
Some types of papilloma virus might prevent cervical cancer
Certain types of papilloma virus might actually prevent cervical cancer, according to a new study by researchers from The University of Manchester.
Humane Research Trust

Contact: Alison Barbuti
alison.barbuti@manchester.ac.uk
44-016-172-58383
University of Manchester

Public Release: 10-Apr-2013
Proceedings of the National Academy of Sciences
UNC researchers engineer 'protein switch' to dissect role of cancer's key players
Researchers at the University of North Carolina at Chapel Hill School of Medicine have "rationally rewired" some of the cell's smallest components to create proteins that can be switched on or off by command. These "protein switches" can be used to interrogate the inner workings of each cell, helping scientists uncover the molecular mechanisms of human health and disease.
NIH/National Cancer Institute, National Institutes of Health, NIH/National Institute of Environmental Health Sciences

Contact: Les Lang
llang@med.unc.edu
919-966-9366
University of North Carolina Health Care

Public Release: 9-Apr-2013
AACR Annual Meeting 2013
TGen-Scottsdale Healthcare clinical trial finds new class of cancer drugs safe and effective
The safety and preliminary efficacy of a new class of tumor fighting drugs were reported today by Scottsdale Healthcare's Virginia G. Piper Cancer Center Clinical Trials and the Translational Genomics Research Institute. Early results from the phase I, first in-human study of an RNA interface drug were announced during the American Association for Cancer Research Annual Meeting 2013.

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute

Public Release: 9-Apr-2013
AACR Annual Meeting 2013
TGen-Scottsdale Healthcare clinical trial results for BIND-014 presented at AACR 2013
The nanoparticle drug BIND-014 is effective against multiple solid tumors, according to results generated by the Translational Genomics Research Institute and Scottsdale Healthcare, and presented today at the American Association for Cancer Research Annual Meeting 2013.

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute

Public Release: 9-Apr-2013
AACR Annual Meeting 2013
AACR news: Six2 homeoprotein allows breast cancer cells to detach and metastasize
In results presented at the AACR Annual Meeting 2013, researchers from the University of Colorado Cancer Center show that the Six2 homeoprotein, while not involved in primary tumor growth, allows cells to detach from substrates and to survive their transition through the bloodstream to faraway sites of metastasis.

Contact: Garth Sundem
garth.sundem@ucdenver.edu
805-559-2023
University of Colorado Denver

Public Release: 9-Apr-2013
Journal of Clinical Oncology
First genetic factor in prostate cancer prognosis identified
Patients with prostate cancer and hereditary mutations in the BRCA2 gene have a worse prognosis and lower survival rates than do the rest of the patients with the disease.

Contact: Nuria Noriega
comunicacion@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)

Public Release: 9-Apr-2013
New Phytologist
Reliably higher levels of healthy compound in Beneforte broccoli
Field trials and genetic studies have shown that a new variety of broccoli reliably yields higher levels of a health-promoting compound. Broccoli contains a compound called glucoraphanin, which has been shown to promote health by maintaining cardiovascular health and a reduction in the risk of cancer. A long term breeding programme to increase glucoraphanin levels has resulted in the commercial release of Beneforte broccoli. Beneforte was developed by crossing standard broccoli with a wild relative.
Biological Sciences Research Council

Contact: Andrew Chapple
andrew.chapple@ifr.ac.uk
44-016-032-51490
Norwich BioScience Institutes

Public Release: 9-Apr-2013
PLOS ONE
2-drug combo more effective in treating sarcomas, Moffitt Cancer Center study shows
Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have found that when given together, a two-drug combination acts synergistically in test animals modeled with sarcoma tumors. They report that the drug combination of MK-1775 and gemcitabine resulted in a 70 percent decrease in the tumor volume when compared to receiving one drug or the other.

Contact: Kim Polacek
kim.polacek@moffitt.org
813-745-7408
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 9-Apr-2013
AACR Annual Meeting 2013
UCLA researchers find potential link between auto pollution, some childhood cancers
Researchers at UCLA's Fielding School of Public Health, led by Julia Heck, assistant researcher in the department of epidemiology and member of the Jonsson Comprehensive Cancer Center, have found a possible link between exposure to traffic-related air pollution and several childhood cancers in the first study on traffic air pollution and childhood cancers (other than leukemia, lymphomas and brain tumors).

Contact: Shaun Mason
smason@mednet.ucla.edu
310-206-2805
University of California - Los Angeles

Public Release: 9-Apr-2013
AACR Annual Meeting 2013
AACR: Positive data supports advancing BIND-014 to phase 2 clinical trials for solid tumors
BIND Therapeutics clinical investigators presented Phase 1 results with BIND-014, its targeted docetaxel Accurin, in 28 heavily-pretreated patients with advanced or metastatic solid tumors. BIND-014 was shown to be generally safe and well-tolerated at the established maximum tolerated dose and showed encouraging signs of anti-tumor activity including one complete response, three partial responses and five patients with stable disease lasting at least four cycles.
BIND Therapeutics

Contact: Kathryn Morris
kathryn@theyatesnetwork.com
845-635-9828
The Yates Network

Public Release: 9-Apr-2013
Breast Cancer Research and Treatment
25 percent don't complete recommended breast cancer treatment
One-quarter of women who should take hormone-blocking therapies as part of their breast cancer treatment either do not start or do not complete the five-year course, according to a new study led by University of Michigan Comprehensive Cancer Center researchers.
NIH/National Cancer Institute, NIH/National Institute for Nursing Research, American Cancer Society

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Showing releases 301-325 out of 1201.

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