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Showing releases 301-325 out of 1281.

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Public Release: 17-Dec-2015
Chemistry and Biology
Probing the mystery of how cancer cells die
A new study sheds light on the role sphingolipids play in the death of cancer cells. The research traces how levels of various sphingolipids spike inside cancer cells when the cells are undergoing a highly organized form of cellular death called apoptosis.

Contact: Charlotte Hsu
University at Buffalo

Public Release: 17-Dec-2015
JAMA Oncology
When cancer of unknown origin strikes, patient's family members face increased risk
Family members of patients with cancers of unknown origin have a higher risk for getting those and other types of cancers.
NIH/National Cancer Institute, Huntsman Cancer Foundation, American College of Gastroenterology

Contact: Linda Aagard
University of Utah Health Sciences

Public Release: 17-Dec-2015
JAMA Oncology
Lung cancer found to be genetically different disease in young and older patients
Non-small cell lung cancer (NSCLC) in younger patients is a distinct disease, genetically and biologically, from NSCLC in older patients and may require a different treatment approach, Dana-Farber Cancer Institute scientists have found.
National Institutes of Health, American Society of Clinical Oncology/Conquer Cancer Foundation, Bonnie J. Addario Lung Cancer Foundation, Canadian Institutes of Health Research, Canadian Association of Medical Oncologists, others

Contact: Anne Doerr
Dana-Farber Cancer Institute

Public Release: 17-Dec-2015
A gene for new species is discovered
A University of Utah-led study identified a long-sought 'hybrid inviability gene' responsible for dead or infertile offspring when two species of fruit flies mate with each other. The discovery sheds light on the genetic and molecular process leading to formation of new species, and may provide clues to how cancer develops.
Howard Hughes Medical Institute, Life Sciences Research Foundation, National Institutes of Health, National Science Foundation, Mathers Foundation, and others

Contact: Lee J. Siegel
University of Utah

Public Release: 17-Dec-2015
Experiments explain the events behind molecular 'bomb' seen in cancer cells
Sometimes, in cancer cells, a part of a chromosome looks like it has been pulverized, then put back together incorrectly, leading to multiple mutations. New research from The Rockefeller University describes the cellular events leading to this molecular explosion, which serves as a precursor to cancer.

Contact: Katherine Fenz
Rockefeller University

Public Release: 17-Dec-2015
First evidence to suggest that screening for ovarian cancer may save lives
New results from the world's biggest ovarian cancer screening trial led by UCL suggest that screening based on an annual blood test may help reduce the number of women dying from the disease by around 20 percent. The research, published today (Thursday) in the Lancet, also cautions that longer follow up is needed to establish more certain estimates of how many deaths from ovarian cancer could be prevented by screening.
UK Medical Research Council, Cancer Research UK, UK Department of Health, Eve Appeal

Contact: Harry Dayantis
University College London

Public Release: 16-Dec-2015
Nature Communications
To stop cancer's spread, take out its communication channels
A study by researchers from Brigham and Women's Hospital, published in Nature Communications, offers a new view of how cancer cells extend their reach, co-opting and transforming normal cells through 'metastatic hijacking.' The researchers also find that in pre-clinical models, pharmacological intervention can prevent this hijacking from occurring, pointing to new therapeutic targets for preventing cancer cells from spreading.
National Institutes of Health, DOD/Breast Cancer Research Program Breakthrough Award, American Lung Association, NIH/National Institute of General Medical Sciences

Contact: Haley Bridger
Brigham and Women's Hospital

Public Release: 16-Dec-2015
Science Translational Medicine
New Scripps Florida compound successfully targets hard-to-treat breast cancer
Findings from a new study led by scientists from the Florida campus of the Scripps Research Institute suggest a potent new therapeutic approach for a number of hard-to-treat breast cancers. The study points to an enzyme called casein kinase 1δ, a critical regulator of growth, as a novel and highly vulnerable therapeutic target.
National Institutes of Health, Rendina Family Foundation, Shear Family Foundation, ThinkPink Kids Foundation, State of Florida, Moffitt Cancer Center & Research Institute

Contact: Eric Sauter
Scripps Research Institute

Public Release: 16-Dec-2015
Journal of Clinical Investigation
Research reveals promising novel strategy to target cancer-causing protein
A team of scientists, researchers from the Institute of Molecular and Cell Biology, research institute under the Agency for Science, Technology and Research, Singapore, and VIB/KU Leuven, has revealed the mechanism by which tumor cells elevate levels of MDM4, a protein that is highly expressed in cancer cells but not in normal adult tissues. The team has also found that the mechanism can be interfered with antisense oligonucleotides to suppress cancer growth.

Contact: Sooike Stoops
VIB (the Flanders Institute for Biotechnology)

Public Release: 16-Dec-2015
Journal of the National Cancer Institute
Mathematical model suggests select DCIS patients could delay treatment
Active surveillance could be a viable alternative to surgery and radiation for select patients with ductal carcinoma in situ, or DCIS, according to a mathematical model developed by researchers at Duke University.
National Institute of Health, Swiss National Science Foundation, NIH/National Cancer Institute

Contact: Sarah Avery
Duke University Medical Center

Public Release: 16-Dec-2015
Researchers find out cause of mutations which are not in genetic material
Proteins are like bricks that form our cells and they are built by the orders given by our genetic material, DNA. In human diseases, eventually DNA alterations modify proteins and they don't do their normal function, either by excess or defect. But recently we have started to find alterations of proteins without an obvious damage of the gene that produces them.

Contact: Arantxa Mena Gómez
IDIBELL-Bellvitge Biomedical Research Institute

Public Release: 16-Dec-2015
Journal of Breast Cancer Research and Treatment
New weapon in the fight against breast cancer
Berkeley Lab researchers have developed the first clinically-relevant mouse model of human breast cancer to successfully express functional estrogen receptor positive adenocarcinomas. This model should be a powerful tool for testing therapies for aggressive ER+ breast cancers and for studying luminal cancers -- the most prevalent and deadliest forms of breast cancer.
NIH/National Cancer Institute

Contact: Lynn Yarris
DOE/Lawrence Berkeley National Laboratory

Public Release: 16-Dec-2015
Study shows multiple-dose, targeted radiation more effective for treating pituitary tumors
A recent patient study at Houston Methodist Hospital proved that multiple small doses of highly focused radiation therapy is safer and more effective than a single larger dose of radiation at destroying pituitary gland tumors.

Contact: Katie Wooldridge
Houston Methodist

Public Release: 16-Dec-2015
Wrap up: Key recommendations from AGA's 2015 guidelines
Clinical practice guidelines are critical to reducing physician variation and providing high-quality patient care. In 2015, the American Gastroenterological Association (AGA) issued six clinical practice guidelines, all published in AGA's official journal Gastroenterology, offering current, evidence-based point-of-care recommendations to guide physicians at the bedside.

Contact: Rachel Shubert
American Gastroenterological Association

Public Release: 15-Dec-2015
Cancer Research
Researchers take first step in precision medicine for penile cancer
Researchers have identified potential genetic alterations in penile cancer that could pave the way for targeted treatments.
A. Alfred Taubman Medical Research Institute

Contact: Nicole Fawcett
University of Michigan Health System

Public Release: 15-Dec-2015
Type of electromagnetic field therapy improves survival for patients with brain tumor
Early research indicates that the use of tumor-treating fields, a type of electromagnetic field therapy, along with chemotherapy in patients with a brain tumor who had completed standard chemoradiation resulted in prolonged progression-free and overall survival, according to a study in the Dec. 15 issue of JAMA.

Contact: Roger Stupp, M.D.
The JAMA Network Journals

Public Release: 15-Dec-2015
Cancer Research
Pitt study: New model of collaborative cancer research may help advance precision medicine
A new system that facilitates data and biospecimen sharing among cancer centers may speed cancer research findings from the laboratory to patient care, according to a new study.
NIH/National Cancer Institute

Contact: Jennifer Yates
University of Pittsburgh Schools of the Health Sciences

Public Release: 15-Dec-2015
British Journal of Cancer
Low cost, safe and accurate test could help diagnose rare childhood cancers
A non-invasive, low cost blood test that could help doctors diagnose some types of malignant childhood tumour has been developed by researchers at the University of Cambridge and Addenbrooke's Hospital, Cambridge University Health NHS Foundation Trust.
Sparks, Great Ormond Street Hospital Children's Charity, Cancer Research UK

Contact: Craig Brierley
University of Cambridge

Public Release: 15-Dec-2015
Kidney International
Newer cancer drug may help protect kidneys from damage caused by older drug
A class of drugs used increasingly to help fight cancer may have the additional benefit of protecting the kidneys when packaged with the powerful chemotherapy agent cisplatin.

Contact: Toni Baker
Medical College of Georgia at Augusta University

Public Release: 15-Dec-2015
Journal of National Cancer Institute
Study: Eliminating cost for colorectal cancer screening doesn't improve screening rates
Making colonoscopy available at no cost to eligible Medicare beneficiaries under the Affordable Care Act (ACA) did not increase the number of people in this target population who regularly undergo the procedure, says a new large scale national study from University Hospitals Case Medical Center Seidman Cancer Center. Interestingly, the same analysis found that rates of routine mammography significantly increased following the ACA's mandate for low or no cost screenings for Medicare recipients.

Contact: Alicia Reale
University Hospitals Case Medical Center

Public Release: 15-Dec-2015
Journal of Biological Chemistry
FAU researchers find new mechanism cells use to eat each other before they become toxic
Just like PAC-MAN® gobbles through a maze of dots eating and destroying its aggressors, researchers at FAU have revealed for the first time how a similar mechanism in the eye lens does exactly the same thing. They discovered that cells in close proximity to each other can sense when a cell is dying due to environmental stressors like UV light and smoke, and eat the cell before it becomes toxic.
National Institutes of Health, National Eye Institute, RO1 grant EY13022 and a gift from the Rand Eye Institute of Deerfield Beach, Fla.

Contact: Gisele Galoustian
Florida Atlantic University

Public Release: 15-Dec-2015
Alternative and Complementary Therapies
Not ordinary growing pains
A recent study at Rush shows that acupuncture may be a safe and effective adjunctive integrative medicine treatment for chronic pain in pediatric patients. Results of the study were published in the December 2015 issue of Alternative and Complementary Therapies.

Contact: Nancy DiFiore
Rush University Medical Center

Public Release: 15-Dec-2015
Journal of American College of Surgeons
Preoperative use of blood-thinning drugs is safe for cancer patients
Among patients undergoing major cancer operations, the preoperative use of blood-thinning drugs such as heparin does not increase rates of major bleeding or transfusions, and is associated with a decreased risk of blood clots, according to new study results published online in the Journal of the American College of Surgeons ahead of print publication early next year.

Contact: Devin Rose
American College of Surgeons

Public Release: 14-Dec-2015
Endocrinology Today
Medication protects fertility and defense system during chemotherapy
Researchers found the potent humanin analogue protected male germ cells, which are essential to fertility, and white blood cells, which are the soldiers in the body's defense system, during chemotherapy. They also reported that HNG reduced metastases, or the spread of cancer cells to other organs in the body.
UCLA Clinical and Translational Science Institute, National Institutes of Health

Contact: Laura Mecoy
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed)

Public Release: 14-Dec-2015
New method of diagnosing deadly fungal lung infection in leukemia patients discovered
A team of researchers have discovered a new way for early detection of a potentially deadly fungal infection in patients with suppressed immune systems such as those being treated for leukemia or have had an organ transplant.

Contact: Donna Ramirez
University of Texas Medical Branch at Galveston

Showing releases 301-325 out of 1281.

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