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Showing releases 301-325 out of 1386.

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Public Release: 24-May-2016
Cancer Prevention Research
Sequencing analysis identifies genomic alterations in colorectal precancers
Whole-exome sequencing of both colorectal adenomas (precancers often called polyps) and intestinal mucosa at risk for developing into adenomas from patients with familial adenomatous polyposis (FAP) has generated a comprehensive picture of the genomic alterations that characterize the evolution of normal mucosa to precancer.
National Institutes of Health, MD Anderson Cancer Center Institutional Research Grant Program, Feinberg family, Janice Davis Gordon Memorial in Colorectal Cancer Prevention Research, Schissler Foundation, Spanish Ministry of Economy and Competitiveness

Contact: Lauren Riley
American Association for Cancer Research

Public Release: 24-May-2016
Cancer Prevention Research
MD Anderson study uncovers early genetic changes in premalignant colorectal tissue
Researchers at The University of Texas MD Anderson Cancer Center have discovered mutations that may fuel early cancer growth in precancerous colorectal tissue from high-risk patients.

Contact: Clayton R. Boldt
University of Texas M. D. Anderson Cancer Center

Public Release: 24-May-2016
Nature Communications
Cell Labelling via Photobleaching: A precious ally for scientific research
A multidisciplinary team of researchers gives birth to a unique method that enables instant, specific labeling of individual cells, Cell Labelling via Photobleaching (CLaP). This method will become a precious ally in a wide range of scientific research, with particular applications for genomics.
Natural Sciences and Engineering Research Council of Canada, Fonds de recherché santé du Québec, Canadian Institutes of Health Research, Genome Canada, FROUM

Contact: Julie Gazaille
University of Montreal

Public Release: 24-May-2016
Digestive Disease Week
Colorectal cancer rate rising among younger people
A new study shows the rate of colorectal cancer (CRC) continues to increase in individuals under 50 years old, despite the fact that the overall rate of the disease has been declining in recent years. Following examination of more than 1 million CRC patient records over 10 years, researchers suggested that health-care providers should be more vigilant about detecting symptoms in younger patients. The findings were presented at Digestive Disease Week®.

Contact: Aimee Frank
Digestive Disease Week

Public Release: 24-May-2016
2016 Asia Pacific Lung Cancer Conference (APLCC)
APLCC 2016 calls on Asian-Pacific governments to help reduce lung cancer deaths
The biennial Asia Pacific Lung Cancer Conference was successfully organized in Chiang Mai, Thailand, by the International Association for the Study of Lung Cancer, and others. More than 870 participants from 26 countries with a wide range of expertise spanning prevention, treatment, research, and care and support fields actively participated in this regional meeting.

Contact: Jeff Wolf
International Association for the Study of Lung Cancer

Public Release: 24-May-2016
Nature Communications
Research points to possible new prevention strategies for ovarian cancer
The discovery of early changes in the cells of the Fallopian tubes of women carrying the BRCA genetic mutation could open the way for new preventative strategies for ovarian cancer, reducing the need for invasive surgery, according to research published today in science journal Nature Communications.

Contact: Wesley Hutchins
University College London

Public Release: 24-May-2016
American Society of Clinical Oncology
Exercise, future anticancer therapy?
First international clinical trial evaluating the effect of intense physical exercise to improve survival of men with advanced prostate cancer.
Movember Foundation

Contact: Isabelle Girard
University of Montreal Hospital Research Centre (CRCHUM)

Public Release: 24-May-2016
PLOS Genetics
May repairs full of mistakes develop into cancer?
A group of researchers at Osaka University found that if DNA damage response does not work when DNA is damaged by radiation, proteins which should be removed remain instead, and a loss of genetic information can be incited, which, when repaired incorrectly, will lead to the tumor formation.
Japan Society for the Promotion of Science, Ministry of Education, Culture, Sports, Science and Technology of Japan

Contact: Saori Obayashi
Osaka University

Public Release: 24-May-2016
International Journal of Epidemiology
Living near a landfill could damage your health
According to research published today in the International Journal of Epidemiology, health is at risk for those who live within five kilometres of a landfill site.
Lazio Waste General Directorate

Contact: Chloe Foster
Oxford University Press

Public Release: 24-May-2016
Nature Medicine
Targeted treatment for liver cancer under way
Researchers at the University of Eastern Finland and Eberhard Karls Universität Tübingen have discovered a new molecular mechanism that can be used to inhibit the growth of hepatocellular carcinoma, which is the most common liver cancer. The findings were published in Nature Medicine.
Academy of Finland, EU, Deutsche Forschungsgemeinschaft

Contact: Antti Poso
University of Eastern Finland

Public Release: 24-May-2016
Journal of Pathology
Vitamin A may help improve pancreatic cancer chemotherapy
The addition of high doses of a form of vitamin A could help make chemotherapy more successful in treating pancreatic cancer, according to an early study by Queen Mary University of London. The promising initial results have led to the potential treatment being tested in a new clinical trial.
Engineering and Physical Sciences Research Council's Knowledge Transfer Network, Pancreatic Cancer Research Fund, Cancer Research UK, Barts Charity

Contact: Joel Winston
Queen Mary University of London

Public Release: 24-May-2016
INNOCOS World Beauty Innovation Summit
Deep learning enters the beauty industry
Insilico Medicine will present their results in applying deep learning to biomarker development and cosmetics applications at the INNOCOS World Beauty Innovation Summit in Vienna June 9-10.

Contact: Qingsong Zhu
InSilico Medicine, Inc.

Public Release: 23-May-2016
Nature Immunology
Harnessing the 'Natural Killer' within us to fight cancer
Walter and Eliza Hall Institute researchers, led by Dr. Sandra Nicholson and Dr. Nicholas Huntington, together with colleagues from the Queensland Institute of Medical Research, are investigating ways to 'switch on' our Natural Killer cells. The researchers identified a protein 'brake' within Natural Killer cells that controls their ability to destroy their target tumor cells.
National Health and Medical Research Council, Victorian Government, Harry J. Lloyd Charitable Trust

Contact: Ebru Yaman
Walter and Eliza Hall Institute

Public Release: 23-May-2016
Proceedings of the National Academy of Sciences
Rare evolutionary event detected in University of Texas lab
Researchers witnessed a rare event and perhaps solved an evolutionary puzzle about how introns, non-coding sequences of DNA located within genes, multiply in a genome. The results address fundamental questions about the evolution of new species and could expand our understanding of gene expression and the causes of diseases such as cancer.

Contact: Kristin Phillips
University of Texas at Austin

Public Release: 23-May-2016
Evidence of link between cancer & light therapy inconclusive but warrants consideration
Two new studies raise enough questions about a possible link between childhood cancer and light therapy for newborn jaundice that clinicians should exercise caution in prescribing it for infants whose jaundice will likely resolve on its own, according to an editorial in Pediatrics. The suggestion of a link, however, should not deter use of the treatment, also known as phototherapy, in babies who otherwise would be at risk of brain damage or hearing loss.

Contact: Irene Sege
Dana-Farber Cancer Institute

Public Release: 23-May-2016
Cancer Discovery
Investigational CDK4/6 inhibitor abemaciclib is active against a range of cancer types
The investigational anticancer therapeutic abemaciclib, which targets CDK4 and CDK6, showed durable clinical activity when given as continuous single-agent therapy to patients with a variety of cancer types, including breast cancer, non-small cell lung cancer (NSCLC), glioblastoma, and melanoma, according to results from a phase I clinical trial.
Eli Lilly and Company

Contact: Lauren Riley
American Association for Cancer Research

Public Release: 23-May-2016
American Society of Clinical Oncology
Dana-Farber research presented at 2016 ASCO conference
A brief look at select studies Dana-Farber Cancer Institute researchers are presenting at the American Society of Clinical Oncology Annual Meeting.

Contact: Teresa M Herbert
Dana-Farber Cancer Institute

Public Release: 23-May-2016
European Society of Human Genetics Conference 2016
American Journal of Human Genetics
Loss of Y chromosome in blood cells associated with developing Alzheimer's disease
Men with blood cells that do not carry the Y chromosome are at greater risk of being diagnosed with Alzheimer's disease. This is in addition to an increased risk of death from other causes, including many cancers. These new findings by researchers at Uppsala University could lead to a simple test to identify those at risk of developing Alzheimer's disease.

Contact: Jan Dumanski
Uppsala University

Public Release: 23-May-2016
International Journal of Molecular Sciences
Study finds breast and ovarian cancer may have similar origins
While breast cancer is the most common cause of cancer death in women worldwide, ovarian cancer also is a significant source of mortality as the fifth leading cause of cancer death among women. These facts reflect the continued need for further understanding and innovation in cancer treatment. A new study published in the International Journal of Molecular Sciences, describes a new concept of how these two cancers may evolve in a similar way and may eventually lead to more effective therapies for both.
American Cancer Society

Contact: Kristen Perfetuo
Boston University Medical Center

Public Release: 23-May-2016
American Association for Cancer Research annual meeting
Purdue research may expand engineered T-cell cancer treatment
Researchers may have figured out a way to call off a cancer cell assassin that sometimes goes rogue. The scientists designed genetically engineered CAR T cells that must be activated and targeted by a small molecule adaptor. The technology has been tested in animal models. A poster presentation describing the work was presented at the American Association for Cancer Research annual meeting in New Orleans.
Endocyte Inc.

Contact: Elizabeth Gardner
Purdue University

Public Release: 23-May-2016
Journal of Thoracic Oncology
Consensus statement on optimizing management of EGFR mutation positive NSCLC patients
The International Association for the Study of Lung Cancer (IASLC) created the 2016 consensus statement on optimizing management of epidermal growth factor receptor (EGFR) mutation positive (M+) non-small cell lung cancer (NSCLC) patients to discuss key pathologic, diagnostic, and therapeutic considerations. The statement also makes recommendations for clinical guidance and research priorities, such as optimal choice of EGFR tyrosine kinase inhibitors, management of brain metastasis, role of re-biopsies, and use of circulating free DNA for molecular studies.

Contact: Jeff Wolf
International Association for the Study of Lung Cancer

Public Release: 23-May-2016
Breast Cancer Research and Treatment
Sylvester researchers identify novel treatment for aggressive form of breast cancer
A recent study by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine revealed that triple-negative breast cancer, which has generally been unresponsive to hormone receptor-targeted treatments, can indeed be treated using vitamin D and androgen receptor-targeted therapy.

Contact: Patrick Bartosch
University of Miami Miller School of Medicine

Public Release: 23-May-2016
Clinical Cancer Research
Proteins key to unlocking cancer for National Cancer Moonshot
The National Cancer Moonshot initiative needs to move beyond genomics to target the proteins that are driving cancer, according to an Inova Health System and George Mason University collaborative paper published Thursday in the American Association for Cancer Research.

Contact: Michele McDonald
George Mason University

Public Release: 23-May-2016
Chemistry - A European Journal
Rice University lab simplifies total synthesis of anti-cancer agent
Rice University researchers reported the streamlined total synthesis of delta12-prostaglandin J3, a molecule that has been reported as killing leukemic cancer cells. The work has led to the production of numerous designed synthetic derivatives that show even greater potential for fighting many forms of cancer.
National Institutes of Health, Cancer Prevention and Research Institute of Texas, Welch Foundation

Contact: David Ruth
Rice University

Public Release: 23-May-2016
Journal of Medicinal Chemistry
Breast cancer drug discovery offers hope of new treatments
A new drug discovery approach has yielded a potential therapy for breast cancer that may be more effective than existing medicines. Scientists at the University of Edinburgh have identified a chemical compound that is highly effective at blocking the growth of breast cancer cells in the laboratory.

Contact: Jen Middleton
University of Edinburgh

Showing releases 301-325 out of 1386.

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