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Showing releases 301-325 out of 1291.

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Public Release: 22-Mar-2016
Mount Sinai first hospital to treat liver cancer with radiopaque bead
The M1 LUMI™ Bead provides visible confirmation during embolization treatment for liver cancer.

Contact: Lucia Lee
newsmedia@mssm.edu
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 22-Mar-2016
JAMA
New treatment reduces precancerous polyps in hereditary cancer patients
Inheriting a mutation in the APC gene leads to a nearly 100 percent lifetime risk of colorectal cancer. A new study published in the Journal of the American Medical Association, has identified the first prevention treatment for these patients, a two-drug combination that significantly reduces the number and size of precancerous polyps in the small intestine.
NIH/National Cancer institute, Huntsman Cancer Institute, Huntsman Cancer Foundation, American College of Gastroenterology, National Institutes of Health

Contact: Linda Aagard
linda.aagard@hci.utah.edu
801-587-7639
University of Utah Health Sciences

Public Release: 22-Mar-2016
CA: A Cancer Journal for Clinicians
New guideline addresses long-term needs of head and neck cancer survivors
A new American Cancer Society guideline provides clinicians with recommendations on key areas of clinical follow-up care for survivors of head and neck cancer.
Centers for Disease Control and Prevention

Contact: David Sampson
david.sampson@cancer.org
American Cancer Society

Public Release: 22-Mar-2016
Journal of Biological Chemistry
Lymphoma overrides a key protein's quadruple locks
Protein chemists at Johns Hopkins report they are closer to explaining why certain blood cancers are able to crack a molecular security system and run rampant.
NIH/National Cancer Institute, Johns Hopkins University Institute for Cell Engineering, Leukemia and Lymphoma Society

Contact: Catherine Gara
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine

Public Release: 22-Mar-2016
JAMA
Drug combination reduces polyps for patients with high risk for colorectal cancer
In a study appearing in the March 22/29 issue of JAMA, Deborah W. Neklason, Ph.D., N. Jewel Samadder, M.D., M.S., of the Huntsman Cancer Institute, University of Utah, Salt Lake City, and colleagues randomly assigned 92 patients with familial adenomatous polyposis to the drugs sulindac twice daily and erlotinib daily (n = 46) or placebo (n = 46) for 6 months.

Contact: Linda Aagard
Linda.Aagard@hci.utah.edu
801-587-7639
The JAMA Network Journals

Public Release: 21-Mar-2016
Journal of Clinical Oncology
Racial, socioeconomic disparities in genomic test used in early-stage breast cancer
A University of Colorado Cancer Center study published today in the Journal of Clinical Oncology shows that African American patients are significantly less likely to receive a common test that predicts the seriousness of early-stage, estrogen-receptor-positive breast cancer.

Contact: Erika Matich
erika.matich@ucdenver.edu
University of Colorado Anschutz Medical Campus

Public Release: 21-Mar-2016
International Journal of Radiation Oncology, Biology, Physics
Travel burden linked with likelihood of receiving radiation therapy to treat rectal cancer
Increased travel distance to a cancer treatment facility negatively impacts the likelihood that patients with stage II/III rectal cancer will receive radiation therapy (RT) to treat their disease, according to a study analyzing 26,845 patient records from the National Cancer Data Base (NCDB) that was published in the March 2016 issue of International Journal of Radiation Oncology * Biology * Physics (Red Journal), the official scientific journal of the American Society for Radiation Oncology (ASTRO).

Contact: Liz Gardner
liz.gardner@astro.org
703-286-1600
American Society for Radiation Oncology

Public Release: 21-Mar-2016
Annals of Internal Medicine
Pathologists often disagree on breast biopsy results when diagnosing DCIS
A study applying B-Path (Breast Pathology) Study results to patient populations found that pathologists disagree with one another about 8 percent of the time when diagnosing a single breast biopsy slide. Discordance was more likely in cases of DCIS or atypia, with a tendency toward overdiagnosing disease. The findings are published in Annals of Internal Medicine.

Contact: Cara Graeff
cgraeff@acponline.org
215-351-2513
American College of Physicians

Public Release: 21-Mar-2016
Cytoskeleton
New way to treat cancer and vessel diseases
Cell biologists from the Lomonosov Moscow State University discovered a new way of regulating of cell motility -- this discovery will make possible development of new drugs for curing onco- and vessel diseases.

Contact: Vladimir Koryagin
science-release@rector.msu.ru
Lomonosov Moscow State University

Public Release: 21-Mar-2016
Nature Immunology
A healthy gut could help prevent deadly side effect of bone marrow transplant
Researchers found a metabolite in the gut microbiome that could improve outcomes after bone marrow transplant. Butyrate was significantly reduced in the intestinal tract of experimental mice that received bone marrow transplant. When the researchers increased butyrate in these mouse models, they saw a decrease in the incidence and severity of graft vs. host disease.
National Institutes of Health

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 21-Mar-2016
JAMA Pediatrics
Review and view of future in cancer in adolescents, young adults
A narrative review published online by JAMA Pediatrics examines the current status of cancer in adolescents and young adults and offers a view of the future.

Contact: Ronald D. Barr
rbarr@mcmaster.ca
The JAMA Network Journals

Public Release: 21-Mar-2016
Proceedings of the National Academy of Sciences
Nanoparticle-based cancer therapies shown to work in humans
A team of researchers led by Caltech scientists have shown that nanoparticles can function to target tumors while avoiding adjacent healthy tissue in human cancer patients. The findings demonstrate that nanoparticle-based therapies can act as a 'precision medicine' for targeting tumors while leaving healthy tissue intact.
NIH/National Cancer Institute, National Institutes of Health, Cerulean Pharma Inc.

Contact: Deborah Williams-Hedges
debwms@caltech.edu
626-395-3227
California Institute of Technology

Public Release: 21-Mar-2016
Lancet Oncology
High-risk lung cancer patients may not need annual screenings
Most high-risk lung cancer patients might not need annual low-dose computed tomography (LDCT) screenings if they are cleared of disease in their initial test, according to a study led by a Duke Cancer Institute researcher.

Contact: Sarah Avery
sarah.avery@duke.edu
919-660-1306
Duke University Medical Center

Public Release: 21-Mar-2016
Nature Protocols
Individualized cancer treatment targeting the tumor, not the whole body, a step closer
QUT researchers have developed a new 3-D printable hydrogel that opens the way to rapid, personalized cancer treatment by enabling multiple, simultaneous tests to find the correct therapy to target a particular tumor.
Harvard Club of Australia Foundation, National Health and Medical Research Council, Australian Research Council, National Breast Cancer Foundation, Queensland Cancer Council

Contact: Niki Widdowson
n.widdowson@qut.edu.auQUT
61-731-382-999
Queensland University of Technology

Public Release: 21-Mar-2016
Nanomedicine: Nanotechnology, Biology, and Medicine
UGA researchers find potential treatment for prostate cancer
Researchers at the University of Georgia have created a new therapeutic for prostate cancer that has shown great efficacy in mouse models of the disease. They published their findings recently in the journal Nanomedicine: Nanotechnology, Biology and Medicine. The treatment is designed to inhibit the activity of a protein called PAK-1, which contributes to the development of highly invasive prostate cancer cells.
National Institutes of Health, UGA College of Pharmacy, UGA Research Foundation, American Legion, College Scientists Foundation Award

Contact: Stephanie Schupska
schupska@uga.edu
706-542-6927
University of Georgia

Public Release: 21-Mar-2016
Nature Reviews Genetics
Beyond DNA: TGen points the way to enhanced precision medicine with RNA sequencing
Researchers at the Translational Genomics Research Institute (TGen) are showing how genetic analysis using RNA sequencing can vastly enhance that understanding, providing doctors and their patients with more precise tools to target the underlying causes of disease, and help recommend the best course of action. Published today in the journal Nature Reviews Genetics, TGen scientists highlight the many advantages of using RNA-sequencing in the detection and management of everything from cancer to infectious diseases
Ben & Catherine Ivy Foundation of Scottsdale, National Center for Advancing Translational Sciences, Stand Up To Cancer-Melanoma Research Alliance Melanoma Dream Team Translational Cancer Research Grant

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute

Public Release: 21-Mar-2016
EMBO Reports
'Silencer molecules' switch off cancer's ability to spread around body
Scientists have revealed that a key molecule in breast and lung cancer cells can help switch off the cancers' ability to spread around the body. The findings by researchers at Imperial College London, published in the journal EMBO Reports, may help scientists develop treatments that prevent cancer travelling around the body -- or produce some kind of test that allows doctors to gauge how likely a cancer is to spread.
National Institute for Health Research Imperial Biomedical Research Centre, Medical Research Council, Action Against Cancer and the Cancer Treatment and Research Trust

Contact: Kate Wighton
k.wighton@imperial.ac.uk
44-020-759-42410
Imperial College London

Public Release: 21-Mar-2016
PLOS ONE
Free pap screening did not increase participation
1,562 women were offered free gynecological pap test screening in three socioeconomically disadvantaged areas in Gothenburg, in 2013. A new study from Sahlgrenska Academy, Narhalsan and the Regional Cancer Center West now shows that these women did not participate to a greater degree than the group that was offered the screening for the usual fee.

Contact: Emilia Alfonzo, Researcher at University of Gothenburg
emilia.alfonzo@vgregion.se
University of Gothenburg

Public Release: 18-Mar-2016
American Journal of Pathology
New effects of ketamine abuse uncovered
Research conducted by scientists at the University of York has revealed how recreational ketamine abuse damages the bladder.
Wellcome Trust

Contact: Saskia Angenent
saskia.angenent@york.ac.uk
44-019-043-23918
University of York

Public Release: 18-Mar-2016
American Journal of Pathology
New gene identified as cause, early indicator of breast cancer
When mutated, a gene known for its ability to repair DNA, appears to instead cause breast cancer, scientists report.

Contact: Toni Baker
tbaker@augusta.edu
706-721-4421
Medical College of Georgia at Augusta University

Public Release: 18-Mar-2016
United States & Canadian Academy of Pathology Annual Meeting
Moffitt pathologists identify new potential target in ovarian serous cancer
Moffitt Cancer Center researchers discovered that patients with ovarian serous cancer and an overexpression of the HER4 protein are less likely to respond to chemotherapy and have a lower rate of survival. That's according to a study Carolina Strosberg, M.D., is presenting this week at the 2016 United States and Canadian Academy of Pathology (USCAP) Annual Conference in Seattle, Washington.

Contact: Lisa Chillura
lisa.chillura@moffitt.org
813-745-1353
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 18-Mar-2016
Pan Pacific Symposium on Stem Cells and Cancer Research
Cell Transplantation
Cell Transplantation research presented at Eighth Annual PPSSC Conference
Studies published in the May 2016 issue of Cell Transplantation (25(5)) were presented at the 8th Annual Meeting of the Pan Pacific Symposium on Stem Cells and Cancer Research, held in in Hsinchu, Taiwan from April 11-13 of 2015. Researchers presented papers on targeting stem cells, clinical trials and translation, emerging drug targets in development and discovery, cutting edge research in stem cell and immune modulation, and adipose-derived stem cell plasticity for regenerative medicine.

Contact: Robert Miranda
bob@cognizantcommunication.com
Cell Transplantation Center of Excellence for Aging and Brain Repair

Public Release: 18-Mar-2016
Scientific Reports
Stanford scientists develop new technique for imaging cells and tissues under the skin
A team of Stanford Bio-X scientists developed the first technique for viewing cells and tissues in three dimensions under the skin. The work could improve diagnosis and treatment for some forms of cancer and blindness.
US Air Force, NIH/Directors Office, National Science Foundation, Damon Runyon Cancer Research Foundation, Susan G. Komen Breast Cancer Foundation, Mary Kay Foundation, Donald E. and Delia B. Baxter Foundation

Contact: Amy Adams
amyadams@stanford.edu
650-796-3695
Stanford University

Public Release: 17-Mar-2016
Emerging Infectious Diseases
TGen helps track down deadly bloodstream infection
The Translational Genomics Research Institute (TGen), working with international investigators, have discovered the source of a potential deadly blood infection in more than 50 South American cancer patients. All of the patients infected with S. Kiliense received ondansetron from the same source, a pharmaceutical company in Columbia.

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute

Public Release: 17-Mar-2016
ACS Central Science
Stanford chemists develop an ultra-sensitive test for cancers, HIV
Catching a disease in its earliest stages can lead to more effective therapies. Stanford chemists have increased the likelihood of detecting these diseases via a test that is thousands of times more sensitive than current diagnostics.

Contact: Bjorn Carey
bccarey@stanford.edu
650-725-1944
Stanford University

Showing releases 301-325 out of 1291.

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