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Showing releases 301-325 out of 1331.

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Public Release: 20-Apr-2015
Nature Medicine
Pancreatic cancer loses viral defenses when talking with supporting cells
Ottawa researchers have unlocked a way to make pancreatic cancer cells more vulnerable to cancer-killing viruses, known as oncolytic viruses. Outlined in a paper published today by Nature Medicine, the scientists have discovered how they can exploit the communication, or cross-talk, between pancreatic cancer and a specific cell type that supports the tumor. They found that this cross-talk weakens the ability of both cell types to fight off cancer-fighting viruses.
Terry Fox Research Institute, Canadian Institutes of Health Research, Ontario Institute for Cancer Research, Alberta Innovative Health Solutions, Natural Sciences and Engineering Research Council of Canada, Ottawa Regional Cancer Foundation

Contact: Lois Ross
loross@ohri.ca
613-297-8315
Ottawa Hospital Research Institute

Public Release: 20-Apr-2015
American Association for Cancer Research Annual Meeting 2015
Cancer-inflammation 'vicious cycle' detailed in new study
New findings hidden within the complex machinery behind the chronic inflammation-cancer feedback loop are presented today by researchers from the University of Pittsburgh Cancer Institute, partner with UPMC Cancer Center, at the American Association for Cancer Research (AACR) Annual Meeting in Philadelphia.
National Institutes of Health, NIH/National Cancer Institute, Fondazione RiMED

Contact: Allison Hydzik
hydzikam@upmc.edu
412-647-9975
University of Pittsburgh Schools of the Health Sciences

Public Release: 20-Apr-2015
Current Oncology
South-Asian women more likely to be diagnosed with later stage breast cancer: Study
South-Asian women are more likely to be diagnosed with later stage breast cancer compared to the general population, while Chinese women are more likely to be diagnosed with early stage cancer, according to a new study by Women's College Hospital and the Institute for Clinical Evaluative Sciences.
Ontario Institute for Cancer Research, Cancer Care Ontario, Canadian Institutes for Health Research, Institute for Clinical Evaluative Sciences

Contact: Rebecca Cheung
rebecca.cheung@wchospital.ca
416-323-6400 x3210
Women's College Hospital

Public Release: 20-Apr-2015
Oncogene
NFCR-supported scientists discover key factor in brain cancer resistance
Researchers at the NFCR Center for Cancer System Informatics at MD Anderson Cancer Center have discovered a key factor that may explain drug resistance in glioblastoma, the most common and deadliest form of brain cancer.
National Foundation for Cancer Research

Contact: Adam Belmar
abelmar@qga.com
202-680-4865
The Science Coalition

Public Release: 20-Apr-2015
Pancreas
Pancreatic cancer breakthrough: Scientists turn cancer cells into normal cells
Scientists find a novel avenue for therapeutic intervention of the 'silent cancer.'
Hartwell Foundation, Hirshberg Foundation, National Institutes of Health, NIH/National Cancer Institute, National Research Foundation of Korea, Yonsei University College of Medicine

Contact: Susan Gammon
sgammon@sanfordburnham.org
858-795-5012
Sanford-Burnham Medical Research Institute

Public Release: 20-Apr-2015
Proceedings of the National Academy of Sciences
Imaging immunity
A novel approach that allows real-time imaging of the immune system's response to the presence of tumors -- without the need for blood draws or invasive biopsies -- offers a potential breakthrough both in diagnostics and in the ability to monitor efficacy of cancer therapies.
National Institutes of Health, Cancer Research Institute, Calouste Gulbenkian Foundation, Champalimaud Foundation, Portuguese Science and Technology Foundation, Portuguese Ministry of Health, Lustgarten Foundation

Contact: Matt Fearer
fearer@wi.mit.edu
617-452-4630
Whitehead Institute for Biomedical Research

Public Release: 20-Apr-2015
American Association for Cancer Research Annual Meeting 2015
New drug combination shows promise for breaking breast cancer resistance
Researchers from the University of Manchester working with drug development company Evgen Pharma, have developed a new combination of drugs which could overcome treatment resistance and relapse in breast cancer.

Contact: Jamie Brown
jamie.brown@manchester.ac.uk
44-161-275-8383
University of Manchester

Public Release: 20-Apr-2015
American Association for Cancer Research Annual Meeting 2015
Tumor genome sequencing shows the most frequently altered gene in bladder cancer: Telomerase reverse transcriptase
In results presented at the American Association for Cancer Research Annual Meeting 2015, a collaborative study by the University of Colorado Cancer Center and the National Cancer Institute reports that the telomerase reverse transcriptase gene promoter was altered in 69 percent of 54 cases of bladder cancer. Telomerase reverse transcriptase alterations frequently co-occur with alterations in recently identified bladder cancer genes such as STAG2 and KDM6A.

Contact: Garth Sundem
garth.sundem@ucdenver.edu
805-559-2023
University of Colorado Denver

Public Release: 20-Apr-2015
American Association for Cancer Research Annual Meeting 2015
Cancer Epidemiology, Biomarkers & Prevention
Overnight fasting may reduce breast cancer risk in women
A decrease in the amount of time spent eating and an increase in overnight fasting reduces glucose levels and may reduce the risk of breast cancer among women, report University of California, San Diego School of Medicine researchers in the journal Cancer Epidemiology, Biomarkers & Prevention.
NIH/National Cancer Institute, Carol Vassiliadis and Family

Contact: Yadira Galindo
ygalindo@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 20-Apr-2015
Journal of Clinical Oncology
Cancer diagnosis leads to higher quit rates among smokers
The largest study of its kind to date finds smokers diagnosed with cancer were more likely to quit than other smokers.
American Cancer Society

Contact: David Sampson
david.sampson@cancer.org
American Cancer Society

Public Release: 20-Apr-2015
American Association for Cancer Research Annual Meeting 2015
Oral milk thistle extract stops colorectal cancer stem cells from growing tumors
'It's very simple: tumors from mice that were initially fed silibinin had fewer cancer stem cells, were smaller, had lower metabolisms and showed decreased growth of new blood vessels,' says University of Colorado Cancer Center researcher, describing results to be presented at AACR 2015.

Contact: Garth Sundem
garth.sundem@ucdenver.edu
805-559-2023
University of Colorado Denver

Public Release: 20-Apr-2015
American Association for Cancer Research Annual Meeting 2015
Immune therapy tested in study of women with triple-negative breast cancer
Early data in a preliminary human study show that an experimental immune system drug is generally safe and well tolerated in women with metastatic, triple-negative breast cancer, a persistently difficult form of the disease to treat.
Genentech, Merck, EMD Serono, Amplimmune, Maxcyte

Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medicine

Public Release: 20-Apr-2015
Most Americans say medical marijuana shouldn't be used by kids or in front of kids
Medical marijuana and children don't mix, most Americans say.

Contact: Beata Mostafavi
bmostafa@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 20-Apr-2015
European Urology
Use of radiotherapy after prostate cancer surgery declining, despite evidence of benefit
Despite strong evidence and guidelines supporting its use, post-surgical radiation therapy for prostate cancer patients at risk of recurrence is declining in the United States.
American Cancer Society

Contact: David Sampson
david.sampson@cancer.org
American Cancer Society

Public Release: 20-Apr-2015
American Association for Cancer Research Annual Meeting 2015
Long non-coding RNA modulates colorectal cancer metabolism
Long non-coding RNAs are unusual in that they don't encode proteins like normal RNA. Yet they do play a role in regulating cellular functions and interest cancer researchers.

Contact: Ron Gilmore
rlgilmore1@mdanderson.org
713-745-1898
University of Texas M. D. Anderson Cancer Center

Public Release: 20-Apr-2015
PLOS Computational Biology
New tactic targets brain tumors
Patients who are obese, diabetic or both have the highest incidence of brain tumors, and they offer a clue that insulin is a factor for some glioblastoma patients. But a new Rice University study suggests drugs tested on such tumors targeted the wrong molecules.
National Science Foundation

Contact: David Ruth
david@rice.edu
713-348-6327
Rice University

Public Release: 20-Apr-2015
Nature Chemistry
Happily ever after: Scientists arrange protein-nanoparticle marriage
University at Buffalo researchers have discovered a way to easily and effectively fasten proteins to nanoparticles -- essentially an arranged marriage -- by simply mixing them together. The biotechnology, described April 20 online in the journal Nature Chemistry, is in its infancy. But it already has shown promise for developing an HIV vaccine and as a way to target cancer cells.
National Institutes of Health

Contact: Cory Nealon
cmnealon@buffalo.edu
716-645-4614
University at Buffalo

Public Release: 20-Apr-2015
American Journal of Hematology
Decreased red blood cell clearance predicts development and worsening of serious diseases
Massachusetts General Hospital investigators have found the probable mechanism underlying a previously described biomarker associated with the risk of developing serious diseases ranging from cancer to cardiovascular disease and the risk of serious complications.
NIH/National Institute for Diabetes and Kidney Disease, National Institutes of Health, Abbott Hematology

Contact: McKenzie Ridings
mridings@partners.org
617-726-0274
Massachusetts General Hospital

Public Release: 20-Apr-2015
Lancet Oncology
Adjuvant Ipilimumab effects survival after high risk lymph node and melanoma resection
Results of an EORTC trial appearing in The Lancet Oncology show that adjuvant Ipilimumab significantly improves recurrence-free survival in patients with completely resected stage III melanoma at high risk of disease recurrence, but that this treatment was also associated with a high rate of immune-related adverse events.
Bristol-Myers Squibb

Contact: John Bean
john.bean@eortc.be
European Organisation for Research and Treatment of Cancer

Public Release: 20-Apr-2015
Statistics and Public Policy
Higher-than-expected pediatric cancer rates identified in 2 Florida areas
Higher-than-expected rates of pediatric cancers have been identified in the Miami metro area and an area west of the Everglades in a series of five statistical analyses conducted for Science and Public Policy, an open-access, online public-policy journal published by the American Statistical Association.

Contact: Jeff Myers
jeffrey@amstat.org
703-684-1221 x1865
American Statistical Association

Public Release: 20-Apr-2015
New breast cancer screening analysis confirms biennial interval optimal for average risk women
Results from a second comprehensive analysis of mammography screening, this time using data from digital mammography, confirms findings from a 2009 analysis of film mammography: biennial (every two years) screening offers a favorable balance of benefits to harm for women ages 50 to 74 who have an average risk of developing breast cancer.
National Institutes of Health

Contact: Karen Teber
km463@georgetown.edu
Georgetown University Medical Center

Public Release: 20-Apr-2015
American Association for Cancer Research Annual Meeting 2015
Clinical Cancer Research
Throwing light on how to conduct a personalized pancreas cancer clinical trial
Australian leaders of an ongoing pancreatic cancer clinical trial known as the Individualized Molecular Pancreatic Cancer Therapy or 'IMPaCT' trial, have been learning ways to bring about about a new paradigm of personalized cancer care for pancreatic cancer and other aggressive cancer types.
National Health and Medical Research Council of Australia, Cancer Council NSW, Cancer Institute NSW, Queensland Government, Institute of Molecular Bioscience at the University of Queensland, Avner Nahmani Pancreatic Cancer Foundation

Contact: Alison Heather
a.heather@garvan.org.au
61-292-958-128
Garvan Institute of Medical Research

Public Release: 20-Apr-2015
EMBO Journal
Cancer gene unintentionally ends the life of cancer cells, turns off life supporting genes
A new study from the University of Wurzburg, Germany, and the University of Helsinki, Finland, suggests that Myc cancer gene makes cells to commit suicide by repressing life supporting 'well-being' genes. These findings provide new opportunities to develop drugs, which could switch Myc from a cancer driver gene to a deadly assassin of the cancer cells.

Contact: Dr. Juha Klefström
juha.klefstrom@helsinki.fi
358-294-125-493
University of Helsinki

Public Release: 20-Apr-2015
Analyst
Detecting lung cancer at an early stage
A new diagnostic method, namely spectral histopathology, facilitates marker-free detection of individual subtypes of lung cancers. It was developed by researchers at the PURE consortium at Ruhr-Universität Bochum. They have successfully applied it in collaboration with clinicians at the Ruhrlandklinik in Essen. It is an automated imaging process which, by classifying specific forms of lung cancer, facilitates a prognosis regarding a tumor's aggressiveness.
Deutsche Gesetzliche Unfallversicherung

Contact: Dr. Klaus Gerwert
gerwert@bph.rub.de
49-234-322-4461
Ruhr-University Bochum

Public Release: 20-Apr-2015
American Association for Cancer Research Annual Meeting 2015
MD Anderson study seeks earlier ovarian cancer detection
Successful ovarian cancer treatment often relies on catching it early. A study at the University of Texas MD Anderson Cancer Center may help point to a new method for women at risk.

Contact: Ron Gilmore
rlgilmore1@mdanderson.org
713-745-1898
University of Texas M. D. Anderson Cancer Center

Showing releases 301-325 out of 1331.

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