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Showing releases 51-75 out of 1255.

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Public Release: 11-Aug-2014
Cancer Epidemiology, Biomarkers & Prevention
Postmenopausal breast cancer risk decreases rapidly after starting reg. physical activity
Postmenopausal women who in the past four years had undertaken regular physical activity equivalent to at least four hours of walking per week had a lower risk for invasive breast cancer compared with women who exercised less during those four years, according to data published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
Institut National du Cancer, Fondation de France, Institut de Recherche en Santé Publique, Mutuelle Générale de l'Education Nationale, Institut de Cancérologie Gustave Roussy, Institut National de la Santé

Contact: Jeremy Moore
American Association for Cancer Research

Public Release: 11-Aug-2014
JAMA Internal Medicine
Bone drugs may not protect osteoporotic women from breast cancer
Osteoporosis drugs known as bisphosphonates may not protect women from breast cancer as had been thought, according to a new study led by researchers at UC San Francisco.

Contact: Laura Kurtzman
University of California - San Francisco

Public Release: 11-Aug-2014
Journal of Experimental Medicine
Tackling liver injury
Researchers uncover a new drug that spurs liver regeneration after surgery.
National Institutes of Health, National Natural Science Foundation of China, Guangxi Natural Science Foundation, Science & Technology Planning Project of Guangxi Province, Science &Technology Planning Project of Guilin City

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 11-Aug-2014
Cancer Cell
Stanford researchers uncover cancer-causing mechanism behind powerful human oncogene
A protein present at high levels in more than half of all human cancers drives cell growth by blocking the expression of just a handful of genes involved in DNA packaging and cell death, according to a new study by researchers at the Stanford University School of Medicine.

Contact: Krista Conger
Stanford University Medical Center

Public Release: 11-Aug-2014
American Chemical Society 248th National Meeting & Exposition
Venom gets good buzz as potential cancer-fighter (video)
Bee, snake or scorpion venom could form the basis of a new generation of cancer-fighting drugs, scientists will report. They devised a method for targeting venom proteins specifically to malignant cells while sparing healthy ones, which reduces or eliminates side effects that the toxins would otherwise cause. Their study is part of the 248th National Meeting of the American Chemical Society. A brand-new video on the research is available at

Contact: Michael Bernstein
American Chemical Society

Public Release: 11-Aug-2014
Nature Chemistry
Synthetic molecule makes cancer self-destruct
Researchers from The University of Texas at Austin and five other institutions have created a molecule that can cause cancer cells to self-destruct by ferrying sodium and chloride ions into the cancer cells. These synthetic ion transporters, described this week in the journal Nature Chemistry, confirm a two-decades-old hypothesis that could point the way to new anticancer drugs while also benefitting patients with cystic fibrosis.
National Creative Research Initiative, Office of Basic Energy Sciences, Chemical Biology Research Center

Contact: Steve Franklin
University of Texas at Austin

Public Release: 11-Aug-2014
Proceedings of the National Academy of Sciences
Scientists demonstrate long-sought drug candidate can halt tumor growth
Scientists at The Scripps Research Institute have disrupted the function of MYC, a cancer regulator thought to be 'undruggable.' The researchers found that a credit card-like molecule they developed somehow moves in and disrupts the critical interactions between MYC and its binding partner.
Pfizer Inc., NIH/National Cancer Institute, The Skaggs Institute for Chemical Biology, Austrian Science Fund

Contact: Mika Ono
Scripps Research Institute

Public Release: 11-Aug-2014
Developmental Cell
How breast cancer usurps the powers of mammary stem cells
During pregnancy, certain hormones trigger specialized mammary stem cells to create milk-producing cells essential to lactation. Scientists at the University of California, San Diego School of Medicine and Moores Cancer Center have found that mammary stem cells associated with the pregnant mammary gland are related to stem cells found in breast cancer.
National Institutes of Health, California Breast Cancer Research Program

Contact: Yadira Galindo
University of California - San Diego

Public Release: 11-Aug-2014
Cancer Cell
Malaria medicine chloroquine inhibits tumor growth and metastases
A recent study by investigators at VIB and KU Leuven has demonstrated that chloroquine also normalizes the abnormal blood vessels in tumors. This blood vessel normalization results in an increased barrier function on the one hand -- thereby blocking cancer cell dissemination and metastasis -- and in enhanced tumor perfusion on the other hand, which increases the response of the tumor to chemotherapy.

Contact: Sooike Stoops
VIB (the Flanders Institute for Biotechnology)

Public Release: 11-Aug-2014
JAMA Internal Medicine
Bisphosphonates for osteoporosis not associated with reduced breast cancer risk
An analysis of data from two randomized clinical trials finds that 3-4 years of treatment with bisphosphonates to improve bone density is not linked to reduced risk of invasive postmenopausal breast cancer.

Contact: Laura Kurtzman
The JAMA Network Journals

Public Release: 11-Aug-2014
Proceedings of the National Academy of Sciences
Aberrant mTOR signaling impairs whole body physiology
The protein mTOR is a central controller of growth and metabolism. Deregulation of mTOR signaling increases the risk of developing metabolic diseases such as diabetes, obesity and cancer. In the current issue of the journal Proceedings of the National Academy of Sciences, researchers from the Biozentrum of the University of Basel describe how aberrant mTOR signaling in the liver not only affects hepatic metabolism but also whole body physiology.

Contact: Olivia Poisson
University of Basel

Public Release: 11-Aug-2014
Cancer Cell
CRI scientists pinpoint gene likely to promote childhood cancers
Researchers at the Children's Medical Center Research Institute at UT Southwestern have identified a gene that contributes to the development of several childhood cancers, in a study conducted with mice designed to model the cancers.

Contact: Randy Sachs
UT Southwestern Medical Center

Public Release: 11-Aug-2014
Proceedings of the National Academy of Sciences
Novel drug action against solid tumors explained
Researchers at UC Davis, City of Hope, Taipai Medical University and National Health Research Institutes in Taiwan have discovered how a drug that deprives the cells of a key amino acid specifically kills cancer cells.

Contact: Carole Gan
University of California - Davis Health System

Public Release: 11-Aug-2014
US lung cancer rates vary by subtype, sex, race/ethnicity, and age
A new analysis confirms that US lung cancer rates are declining overall, but it also uncovers previously unrecognized trends related to cancer subtype, sex, race/ethnicity, and age.

Contact: Evelyn Martinez

Public Release: 10-Aug-2014
Scientists unlock key to blood vessel formation
Scientists from the University of Leeds have discovered a gene that plays a vital role in blood vessel formation, research which adds to our knowledge of how early life develops.
British Heart Foundation, Wellcome Trust, Medical Research Council

Contact: Ben Jones
University of Leeds

Public Release: 8-Aug-2014
Journal of Virology
Editing HPV's genes to kill cervical cancer cells
Using the genome editing tool known as CRISPR, Duke University researchers were able to selectively silence two genes in human papilloma virus that are responsible for the growth and survival of cervical carcinoma cells. After silencing the two HPV genes, the cancer cell's normal self-destruct machinery went into action.
National Institutes of Health

Contact: Karl Bates
Duke University

Public Release: 7-Aug-2014
Nature Communications
Mutations in a gene essential for cell regulation cause kidney cancer in children
Mutations in a gene that helps regulate when genes are switched on and off in cells have been found to cause rare cases of Wilms tumor, the most common kidney cancer occurring in children.
Wellcome Trust, Cancer Research UK

Contact: Henry French
Institute of Cancer Research

Public Release: 7-Aug-2014
Cancer categories recast in largest-ever genomic study
New research partly led by UC San Francisco-affiliated scientists suggests that one in 10 cancer patients would be more accurately diagnosed if their tumors were defined by cellular and molecular criteria rather than by the tissues in which they originated, and that this information, in turn, could lead to more appropriate treatments.

Contact: Peter Farley
University of California - San Francisco

Public Release: 7-Aug-2014
Cell Reports
University of Minnesota research finds key piece to cancer cell survival puzzle
An international team led by Eric A. Hendrickson of the University of Minnesota and Duncan Baird of Cardiff University has solved a key mystery in cancer research: What allows some malignant cells to circumvent the normal process of cell death that occurs when chromosomes get too old to maintain themselves properly?

Contact: Stephanie Xenos
University of Minnesota

Public Release: 7-Aug-2014
Cell Reports
Scientists uncover key piece to cancer cell survival puzzle
A chance meeting between two leading UK and US scientists could have finally helped solve a key mystery in cancer research. Professor Duncan Baird and his team from Cardiff University, working in collaboration with Eric A. Hendrickson from the University of Minnesota, have identified a specific gene that human cells require in order to survive chromosomal defects.

Contact: Chris Jones
Cardiff University

Public Release: 7-Aug-2014
Nature Cell Biology, Cell Cycle
A*Star scientists make breakthroughs in ovarian cancer research
Scientists at A*STAR's Institute of Medical Biology and the Bioinformatics Institute have found new clues to early detection and personalised treatment of ovarian cancer, currently one of the most difficult cancers to diagnose early due to the lack of symptoms that are unique to the illness.
Agency for Science, Technology and Research (A*STAR)

Contact: Vanessa Loh
Biomedical Sciences Institutes (BMSI)

Public Release: 7-Aug-2014
Largest cancer genetic analysis reveals new way of classifying cancer
The work, led by researchers at the UNC Lineberger Comprehensive Cancer Center, UNC-Chapel Hill and other TCGA sites, revamps traditional ideas of how cancers are diagnosed and treated and could also have a profound impact on the future landscape of drug development.
NIH/National Cancer Institute, NIH/National Human Genome Research Institute

Contact: Katy Jones
University of North Carolina Health Care

Public Release: 7-Aug-2014
Nature Communications
Cell mechanics may hold key to how cancer spreads and recurs
Cancer cells that break away from tumors to go looking for a new home may prefer to settle into a soft bed, according to new findings from researchers at the University of Illinois. Some particularly enterprising cancer cells can cause a cancer to spread to other organs or evade treatment to resurface after a patient is thought to be in remission. The researchers found that these tumor-repopulating cells may lurk quietly in stiffer cellular environments, but thrive in a softer space.
National Institutes of Health

Contact: Liz Ahlberg
University of Illinois at Urbana-Champaign

Public Release: 7-Aug-2014
Pancreatic survival rates at standstill for 4 decades
Long-term survival from pancreatic cancer has failed to improve in 40 years -- with the outlook remaining the lowest of the 21 most common cancers, according to new figures published by Cancer Research UK.

Contact: Ailsa Stevens
Cancer Research UK

Public Release: 7-Aug-2014
Cell Reports
Scientists uncover stem cell behavior of human bowel for the first time
For the first time, scientists have uncovered new information on how stem cells in the human bowel behave, revealing vital clues about the earliest stages in bowel cancer development and how we may begin to prevent it.

Contact: Charli Scouller
Queen Mary, University of London

Showing releases 51-75 out of 1255.

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