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Showing releases 51-75 out of 1216. << < 1 | 2 | 3 | 4 | 5 | 6 | 7 > >>
Public Release: 25-Jul-2013
Need for national Canadian strategy for EGFR testing Researchers in Canada examined the barriers to the initial implementation of the national EGFR testing policy. In the September issue of the International Association for the Study of Lung Cancer's journal, the Journal of Thoracic Oncology, researchers conclude that the uptake of EGFR mutation testing dropped substantially once funding from the pharmaceutical industry was discontinued. Contact: Kristal Griffith Public Release: 25-Jul-2013
A lifespan-extending drug has limited effects on aging In the current issue of the Journal of Clinical Investigation, Dan Ehninger and colleagues at the German Center for Neurodegenrative Diseases evaluated age-associated characteristics in mice treated with rapamycin. Contact: Corinne Williams Public Release: 25-Jul-2013
Women's height linked to cancer risk The taller a postmenopausal woman is, the greater her risk for developing cancer, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research. Contact: Jeremy Moore Public Release: 25-Jul-2013
Cancer researchers PTEN discovery provides knowledge to individualize treatment Scientists at the Princess Margaret Cancer Centre have discovered a function of the tumor suppressor gene PTEN that helps explain why certain promising therapies fail in many cancer patients, a finding that could aid in delivering tailored, personalized cancer medicine based on an individual's genetics. Contact: Jane Finlayson Public Release: 25-Jul-2013
Suffocating tumors could lead to new cancer drugs Scientists have discovered a new molecule that prevents cancer cells from responding and surviving when starved of oxygen and which could be developed into new treatments for the disease, according to new research published in the Journal of the American Chemical Society today. Contact: Becky Attwood Public Release: 25-Jul-2013
Researchers find potential new target to treat malignant pleural mesothelioma In the September issue of the International Association for the Study of Lung Cancer's journal, the Journal of Thoracic Oncology, researchers conclude that Ephrin B2 seems to play an important role in malignant pleural mesothelioma cell lines and tumors. Contact: Kristal Griffith Public Release: 25-Jul-2013
Should a woman's ovaries be removed during a hysterectomy for noncancerous disease? Other than a woman's cancer risk, the most important factor that should determine ovarian conservation vs. removal is her age -- whether she is older or younger than 50 -- according to a Review article published in Journal of Women's Health. Contact: Vicki Cohn Public Release: 24-Jul-2013
Large study reveals increased cancer risks associated with family history of the disease A family history of cancer increases the risk of other members of the family developing not only the same cancer but also a different (discordant) cancer, according to a large study of 23,000 people in Italy and Switzerland. The research, published in the leading cancer journal Annals of Oncology, is one of the few large studies of this kind that takes into account other important factors, such as individual characteristics and lifestyles, that could affect the degree of risk as well. Contact: Emma Mason Public Release: 24-Jul-2013
HPV's link to esophageal cancer The human papillomavirus triples the risk of people developing yet another cancer, esophageal squamous cell carcinoma, according to research led by University of New South Wales academics. Contact: Susi Hamilton Public Release: 24-Jul-2013
Hospital mammography recall rates higher The rate at which women get called back for additional imaging after screening mammography may be higher at hospitals than at community office practices, mostly due to differences among the patients, according to a new study. The findings highlight the limitations of recall rates as a quality measure for breast cancer screening. Contact: Linda Brooks Public Release: 24-Jul-2013
RI Hospital study finds differences in mammography recall rate between 2 centers A new study at Rhode Island Hospital has found that academic medical centers have higher rates of recall following mammography than community radiology centers. The study found that patients who received their mammogram at the hospital were typically younger -- average age 56 at the hospital and 63 at the community practice -- and younger patients have a higher rate of recall. The hospital patients also had a higher incidence of previous surgeries and biopsies. Contact: Ellen Slingsby Public Release: 24-Jul-2013
Novel gene target shows promise for bladder cancer detection and treatment Scientists from Virginia Commonwealth University Massey Cancer Center have provided evidence from preclinical experiments that a gene known as melanoma differentiation associated gene-9/syntenin (mda-9/syntenin) could be used as a therapeutic target to kill bladder cancer cells, help prevent metastasis and even be used to non-invasively diagnose the disease and monitor its progression. Contact: John Wallace Public Release: 24-Jul-2013
Researchers target HER1 receptor for peptide cancer vaccine, therapeutic agents Small proteins called peptides are being studied as cancer vaccines and as alternatives to antibody-based drugs and inhibitors now used to treat many malignancies. Researchers have identified two regions on the HER1/EGFR receptor, a protein important for cancer-cell growth and metastasis and for poor patient survival, as targets for peptide agents. The findings could lead to novel vaccines and safer more effective therapies for tumors of the breast, lung, colon and head and neck. Contact: Darrell E. Ward Public Release: 24-Jul-2013
More central line infections seen in children with cancer once they leave the hospital Pediatric cancer patients whose central lines are used to treat them at home develop three times as many dangerous bloodstream infections from their devices than their hospitalized counterparts, according to the results of a new Johns Hopkins Children's Center study. Contact: Ekaterina Pesheva Public Release: 24-Jul-2013
New techniques use lasers, LEDs, and optics to 'see' under the skin A special section just published in the Journal of Biomedical Optics reports on new non-invasive optical techniques using lasers, light-emitting diodes, and spectroscopic methods to probe and render images from beneath the surface of the skin. The technologies have a wide variety of medical and cosmetic applications such as treating burns, identifying cancer, and speeding the healing of wounds. Contact: Amy Nelson Public Release: 24-Jul-2013
URMC study clarifies surgical options for kidney cancer Surgery is often the first step in treating kidney cancer, and new data from the University of Rochester Medical Center, which contradicts earlier research, questions whether removal of only the tumor (partial nephrectomy) is better than removing the entire kidney (radical nephrectomy). Contact: Leslie Orr Public Release: 24-Jul-2013
NYU-Poly nano scientists reach holy grail in label-free cancer marker detection: Single molecules Just months after setting a record for detecting the smallest single virus in solution, researchers at the Polytechnic Institute of New York University announced a new breakthrough: A nano-enhanced version of their biosensor detected a single cancer marker protein and even smaller molecules below the mass of all known markers. This achievement sets a new benchmark for the most sensitive limit of detection, and may significantly advance early disease diagnostics. Contact: Kathleen Hamilton Public Release: 23-Jul-2013
Sharing data with providers associated with plummeting rates of unnecessary medical tests in Sweden The rate of inappropriate cancer scans for low-risk prostate cancer patients in Sweden plummeted in the decade following a joint campaign to curtail such tests, suggest that curtailing unneeded medical tests, an urgent healthcare policy goal in the United States highlighted in the Choosing Wisely Campaign, among other initiatives, is achievable, says Danil V. Makarov, M.D., assistant professor of urology and population health at NYU Langone Medical Center and lead author of the study. Contact: Lorinda Klein Public Release: 23-Jul-2013
Digital PCR technology detects brain-tumor-associated mutation in cerebrospinal fluid Massachusetts General Hospital researchers and their colleagues have used digital versions of a standard molecular biology tool to detect a common tumor-associated mutation in the cerebrospinal fluid of patients with brain tumors. Contact: Sue McGreevey Public Release: 23-Jul-2013
Difference in breast cancer survival between black and white women has not changed substantially In an analysis of five-year survival rates among black and white women diagnosed with breast cancer between 1991 and 2005, black women continued to have a lower rate of survival, with most of the difference related to factors including poorer health of black patients at diagnosis and more advanced disease, rather than treatment differences, according to a study in the July 24/31 issue of JAMA. Contact: Dana Mortensen Public Release: 23-Jul-2013
Keeping centrioles in check to ensure proper cell division How cell division occurs and is coordinated with organismal development is subject of intense research interest, as is how this process malfunctions in the development of tumors. Alex Dammermann and his team from the Max F. Perutz Laboratories of the University of Vienna and the Medical University of Vienna, together with his collaborators from the Institute of Molecular Pathology, have been investigating how the duplication of centrioles is coordinated with the cell cycle. Contact: Alex Dammermann Public Release: 23-Jul-2013
Oxygen -- key to most life -- decelerates many cancer tumors when combined with radiation therapy A multidisciplinary team at UT Southwestern Medical Center has found that measuring the oxygenation of tumors can be a valuable tool in guiding radiation therapy, opening the door for personalized therapies that keep tumors in check with oxygen enhancement. Contact: Alex Lyda Public Release: 23-Jul-2013
Pathways activated in most K9 bone tumors not driving the worst bone tumors CU Cancer Center and CSU Flint Animal Cancer Center study shows NOTCH signaling was elevated in K9 osteosarcoma, but aspects of Notch signaling were noticeably deactivated in the worst cancers. Contact: Garth Sundem Public Release: 23-Jul-2013
Researchers develop new approach for studying deadly brain cancer Human glioblastoma multiforme, one of the most common, aggressive and deadly forms of brain cancer, is notoriously difficult to study. Now a team of engineers has developed a three-dimensional hydrogel that more closely mimics conditions in the brain than other platforms used to study brain cancer. In a paper in the journal Biomaterials, the researchers describe the new material and their approach, which allows them to selectively tune up or down the malignancy of the cancer cells they study. Contact: Diana Yates Public Release: 23-Jul-2013
Researchers reveal the clearest new pictures of immune cells Scientists from The University of Manchester have revealed new images which provide the clearest picture yet of how white blood immune cells attack viral infections and tumors. They show how the cells, which are responsible for fighting infections and cancer in the human body, change the organization of their surface molecules, when activated by a type of protein found on viral-infected or tumor cells. Contact: Alison Barbuti
Showing releases 51-75 out of 1216. << < 1 | 2 | 3 | 4 | 5 | 6 | 7 > >>
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