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Showing releases 76-100 out of 1365.

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Public Release: 16-Jun-2016
Journal of Occupational and Environmental Medicine
Women's long work hours linked to alarming increases in cancer, heart disease
Women who put in long hours for the bulk of their careers may pay a steep price: life-threatening illnesses, including heart disease and cancer. Work weeks that averaged 60 hours or more over three decades appear to triple the risk of diabetes, cancer, heart trouble and arthritis for women, according to new research from The Ohio State University.
US Centers for Disease Control and Prevention, NIH/National Institute of Occupational Safety and Health

Contact: Allard Dembe
adembe@cph.osu.edu
614-292-2129
Ohio State University

Public Release: 16-Jun-2016
JCI Insight
Combined radiotherapy and immunotherapy improve efficacy in a murine lung cancer model
In this issue of JCI Insight, researchers from the NYU Langone Medical Center and the Dana Farber Cancer Institute used a genetically engineered mouse model of non-small cell lung cancer to examine the efficacy of treatment with radiotherapy and a PD-1 inhibitory antibody.
Deutsche Forschungsgemeinschaft, Else Kroner-Fresenius-Stiftung, Damon Runyon Cancer Research Foundation, Starr Consortium for Cancer Research, NIH/National Cancer Institute, National Institutes of Health, Stand Up to Cancer

Contact: Corinne Williams
press_releases@the-jci.org
JCI Journals

Public Release: 16-Jun-2016
Cell Reports
Summer session fruit fly data leads to promising new target in colorectal cancer
University of Colorado Cancer Center study shows role of TIP60 (alongside previously known CDK8) in allowing human colorectal cancer cells to survive at the oxygen-poor centers of tumors.
National Science Foundation, National Institutes of Health

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Anschutz Medical Campus

Public Release: 16-Jun-2016
Genome Research
Cancer-preventing protein finds its own way in our DNA
Geneticists from KU Leuven, Belgium, have shown that tumor protein TP53 knows exactly where to bind to our DNA to prevent cancer. Once bound to this specific DNA sequence, the protein can activate the right genes to repair damaged cells.

Contact: Stein Aerts
stein.aerts@kuleuven.be
32-163-30710
KU Leuven

Public Release: 16-Jun-2016
JAMA Oncology
Extent of resection associated with likelihood of survival in glioblastoma
The extent of resection in patients with glioblastoma, an aggressive and often fatal brain tumor, was associated with the likelihood of survival and disease progression, according to a new study published online by JAMA Oncology.

Contact: Scott Gilbert
Sgilbert1@hmc.psu.edu
717-531-8606
The JAMA Network Journals

Public Release: 15-Jun-2016
Clinical Cancer Research
Chemotherapy may boost immunotherapy power in ovarian cancer
Cancer Research UK scientists have found that women with advanced ovarian cancer may benefit more from immunotherapy drug treatments if they are given straight after chemotherapy.
Cancer Research UK, Swiss Cancer League, European Research Council, Barts and the London Charity

Contact: Simon Shears
simon.shears@cancer.org.uk
44-203-469-8054
Cancer Research UK

Public Release: 15-Jun-2016
British Journal of Cancer
International Tree Nut Council funds study linking tree nut consumption to prostate cancer mortality
New study on nut consumption and prostate cancer published in the British Journal of Cancer.
International Tree Nut Council

Contact: Erin McGraw
erin@motionpr.net
312-670-8943
Motion PR

Public Release: 15-Jun-2016
Clinical Cancer Research
New imaging technique could ID additional ovarian tumors not visible to surgeons' eyes
A newly devised tumor-specific fluorescent agent and imaging system guided surgeons in real time to remove additional tumors in ovarian cancer patients that were not visible without fluorescence or could not be felt during surgery.
On Target Laboratories LLC

Contact: Lauren Riley
lauren.riley@aacr.org
215-446-7155
American Association for Cancer Research

Public Release: 15-Jun-2016
AcademyHealth 2016
Allina Health presents LifeCourse developments at national conference
These are three new tools to help caregivers involved in late life care from LifeCourse in Minneapolis. LifeCourse is a multi-year study to test a unique whole-person approach to late life care.
Robina Foundation

Contact: Gloria O'Connell
gloria.oconnell@allina.com
612-863-4801
Allina Health

Public Release: 15-Jun-2016
Clinical Cancer Research
Presurgery chemotherapy may make advanced ovarian cancers responsive to immunotherapy
Metastatic ovarian cancer patients treated with chemotherapy prior to surgery had altered immune cells in their tumors, and specific alterations identified suggest that immunotherapy given after chemotherapy may help in preventing the cancer from coming back.
Swiss Cancer League, European Research Council, Cancer Research UK, Barts and the London Charity

Contact: Lauren Riley
lauren.riley@aacr.org
215-446-7155
American Association for Cancer Research

Public Release: 15-Jun-2016
2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging
Journal of Nuclear Medicine
PET/CT imaging of prostate cancer proves accurate biopsy guide
Prostate cancer is the leading cancer among men, second only to skin cancer. With surgical removal at the frontline of defense, oncologists are considering prostate-specific molecular imaging at the point of initial biopsy and pre-operative planning to root out the full extent of disease, researchers revealed at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging.

Contact: Laurie Callahan
lcallahan@snmmi.org
Society of Nuclear Medicine

Public Release: 15-Jun-2016
Structure
Engineering the immune system to kill cancer cells
A research team led by University of Notre Dame chemist Brian Baker is developing a new immunotherapy, a treatment that enhances immune system function in order to treat or prevent disease, as a means to more effectively target and kill cancer cells.

Contact: Brian Baker
brian-baker@nd.edu
574-631-9810
University of Notre Dame

Public Release: 15-Jun-2016
Cancer Research
Sylvester scientists provide proof of concept for potential new class of cancer drugs
A recent study led by scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, in collaboration with the Univerity of Maryland School of Pharmacy and StemSynergy Therapeutics, Inc., has identified a small-molecule inhibitor of the Notch pathway, paving the way for a potential new class of personalized cancer medicines. Aberrant activity in the Notch pathway contributes to the initiation and maintenance of cancer stem cells.
NIH/National Cancer Institute, National Institutes of Health

Contact: Patrick Bartosch
patrick.bartosch@med.miami.edu
305-243-8219
University of Miami Miller School of Medicine

Public Release: 15-Jun-2016
Gastroenterology
Penn-led study resolves long-disputed theory about stem cell populations
A team from the University of Pennsylvania has helped identify key characteristics that distinguish reserve stem cells from other stem cell populations that had been purported to have similar properties. The work, which employed single-cell gene expression analyses as well as other cutting-edge techniques, demonstrated that, in the intestines, reserve stem cells are a distinct population from so-called 'label-retaining cells.' The two populations were long believed to be one and the same.
NIH/National Cancer Intistitute, NIH/National Institute for Diabetes and Digestive and Kidney Disorders

Contact: Katherine Unger Baillie
kbaillie@upenn.edu
215-898-9194
University of Pennsylvania

Public Release: 15-Jun-2016
The Lancet
Piping hot drinks may lead to cancer of the esophagus
Drinking piping hot coffee, tea and the caffeine-infused beverage yerba mate probably causes cancer, the World Health Organization announced. USC's Mariana Stern was part of the panel of scientists who came to this determination.

Contact: Zen Vuong
zvuong@usc.edu
213-300-1381
University of Southern California

Public Release: 15-Jun-2016
The BMJ
Seven servings of whole grains a day keep the doctor away
A recent meta-analysis shows that consuming a lot of whole grains decreases the risk of dying prematurely.
Olav og Gerd Meidel Raagholt's Stiftelse for Medisinsk Forskning, and others

Contact: Dagfinn Aune
d.aune@imperial.ac.uk
Norwegian University of Science and Technology

Public Release: 15-Jun-2016
Cancer
Shorter radiation course recommended for early-stage breast cancer patients
Early-stage breast cancer patients receiving a shorter course of whole breast radiation with higher radiation doses per fraction reported equivalent cosmetic, functional and pain outcomes over time as those receiving a longer, lower-dose per fraction course of treatment, according to researchers from the University of Texas MD Anderson Cancer Center.

Contact: Lany Kimmons
rlkimmons@mdanderson.org
713-563-5801
University of Texas M. D. Anderson Cancer Center

Public Release: 14-Jun-2016
Colloids and Surfaces B: Biointerfaces
Sleep hormone helps breast cancer drug kill more cancer cells
Tiny bubbles filled with the sleep hormone melatonin can make breast cancer treatment more effective, which means people need a lower dose, giving them less severe side effects. In a new study published in Colloids and Surfaces B: Biointerfaces, researchers show that the bubbles, called nanostructured lipid carriers, made tamoxifen stronger and help it kill cancer cells.
Drug Applied Research Center, Tabriz University of Medical Sciences

Contact: Aileen Christensen
a.christensen@elsevier.com
31-204-852-053
Elsevier

Public Release: 14-Jun-2016
Oncotarget
MicroRNAs help to predict disease progression in brain tumors
Scientists at the Helmholtz Zentrum München and the Ludwig Maximilians University of Munich have developed a new method of predicting disease progression in gliobastoma patients who have undergone standard treatment. Their findings, published in the journal Oncotarget, show that four miRNAs may hold the vital clue. An application for the corresponding patent has already been filed.

Contact: Dr. Kristian Unger
unger@helmholtz-muenchen.de
49-893-187-3515
Helmholtz Zentrum München - German Research Center for Environmental Health

Public Release: 14-Jun-2016
2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging
Journal of Nuclear Medicine
CT-based calculations improve accuracy of PET for cancer patients
Cancer patients often experience significant fluctuations in weight and lean body mass (LBM). Neglecting to account for these changes can prevent clinicians from obtaining precise data from molecular imaging, but a new method of measuring LBM takes changes in individual body composition into account for better staging of disease and therapy monitoring, say researchers at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI).

Contact: Laurie Callahan
lcallahan@snmmi.org
Society of Nuclear Medicine

Public Release: 14-Jun-2016
Journal of Biological Chemistry
New study explains how very aggressive cancer cells use energy to divide, move
A new study explains how cancer cells use energy to fuel this switch between motion and proliferation. The researchers identified for the first time a connection between a cancer gene that controls motility and how cancer cells metabolize energy to move and divide so quickly.
Metavivor Foundation, Avon Foundation, Breast Cancer Research Foundation, James S. McDonnell Foundation, Liz and Eric Lefkofsky Innovative Research Fund, National Institutes of Health

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 13-Jun-2016
Journal of Clinical Oncology
Screening strategy may predict lethal prostate cancer later in life
Through a prospective study of US men, investigators from Brigham and Women's Hospital and the Harvard T.H. Chan School of Public Health have found that measuring PSA levels in younger men (between the ages of 40 and 59) could accurately predict future risk of lethal prostate cancer later in life. Their findings suggest that screening PSA levels in men at mid-life may help identify those who are at greater risk and should be monitored more closely.

Contact: Haley Bridger
hbridger@partners.org
617-525-6383
Brigham and Women's Hospital

Public Release: 13-Jun-2016
Nature Genetics
Probing proteins' 3-D structures suggests existing drugs may work for many cancers
Examining databases of proteins' 3-D shapes, scientists at Washington University School of Medicine in St. Louis have identified more than 850 DNA mutations that appear to be linked to cancer. The information may expand the number of cancer patients who can benefit from existing drugs.
National Institutes of Health, US Department of Defense, Genetics and Genomics of Disease Pathway at Washington University School of Medicine in St. Louis

Contact: Diane Duke Williams
williamsdia@wustl.edu
314-286-0111
Washington University School of Medicine

Public Release: 13-Jun-2016
Veterinary Comparative Oncology
A common enemy: Through clinical trials, veterinarian fights cancer in animals, humans
A Kansas State University veterinarian is conducting clinical trials to treat cancers in dogs, cats and other companion animals.
American College of Veterinary Internal Medicine Foundation, Mark Derrick Canine Research Fund, Zoetis Animal Health

Contact: Jennifer Tidball
jtidball@k-state.edu
785-532-0847
Kansas State University

Public Release: 13-Jun-2016
2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging
Journal of Nuclear Medicine
FDG PET evaluates immunotherapy for non-small cell lung cancer
Non-small cell lung cancers (NSCLC) have a collective reputation for not responding very well to chemotherapy. Researchers at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) are presenting a means of evaluating an immunotherapy that fights off NSCLC by strengthening a patient's own immune system.

Contact: Laurie Callahan
lcallahan@snmmi.org
Society of Nuclear Medicine

Showing releases 76-100 out of 1365.

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