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Showing releases 76-100 out of 1198. << < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 > >>
Public Release: 6-May-2013
Wip1 could be new target for cancer treatment Researchers have uncovered mutations in the phosphatase Wip1 that enable cancer cells to foil the tumor suppressor p53, according to a study in The Journal of Cell Biology. The results could provide a new target for the treatment of certain cancers. Contact: Rita Sullivan King Public Release: 6-May-2013
Children living near toxic waste sites experience higher blood lead levels resulting in lower IQ Children living near toxic waste sites in lower and middle income countries such as India, Philippines and Indonesia may experience higher blood lead levels, resulting in a loss of IQ points and a higher incidence of mental retardation, according to a study presented today by Kevin Chatham-Stephens, M.D., Pediatric Environmental Health Fellow at the Icahn School of Medicine at Mount Sinai, at the Pediatric Academic Societies annual meeting on May 6 in Washington, DC. Contact: Renatt Brodsky Public Release: 6-May-2013
Minimal dose CT superior to chest X-ray for detection of recurrent lung cancer In this study presented at the 93rd AATS Annual Meeting, investigators from the University of Toronto departments of Thoracic Surgery and Diagnostic Radiology show that minimal dose computed tomography of the thorax offers much greater sensitivity at detecting new or recurrent lung cancer, with equivalent amount of radiation, compared to conventional chest X-rays. Contact: Nicole Baritot Public Release: 6-May-2013
New class of drug targets skin cancer A new class of drug targeting skin cancer's genetic material has been successfully tested in humans for the first time, opening the way to new treatments for a range of conditions from skin cancers to eye diseases. Contact: Susi Hamilton Public Release: 6-May-2013
Activity of cancer inducing genes can be controlled by the cell's skeleton In the latest issue of the journal Oncogene, Florence Janody and her team at the Instituto Gulbenkian de Ciência, identified a novel mechanism by which the activity of Src is limited by the cell's skeleton, limiting the development of tumors. Contact: Inês Domingues Public Release: 5-May-2013
Some prostate cancer patients more likely to die after weekend ER visits Patients with prostate cancer that has metastasized, or spread, to other parts of the body face a significantly higher risk of dying when visiting a hospital emergency department on the weekend instead of on a weekday, according to researchers at Henry Ford Hospital in Detroit. Contact: Dwight Angell Public Release: 5-May-2013
Hospital surgical volume should be considered when judging value of procedures The volume of cases performed at an institution each year has a direct effect on the outcome of surgical procedures, and should always be considered when looking at the benefits of a technique, according to a team of researchers at Henry Ford Hospital in Detroit. Contact: Dwight Angell Public Release: 5-May-2013
Protein complex may play role in preventing many forms of cancer, Stanford study shows Researchers at the Stanford University School of Medicine have identified a group of proteins that are mutated in about one-fifth of all human cancers. The finding suggests that the proteins, which are members of a protein complex that affects how DNA is packaged in cells, work to suppress the development of tumors in many types of tissues. Contact: Krista Conger Public Release: 5-May-2013
Discovery may help prevent chemotherapy-induced anemia Researchers at Albert Einstein College of Medicine have discovered that chemotherapy induces an insidious type of nerve damage inside bone marrow that can cause delays in recovery after bone marrow transplantation. The findings, made in mice and published online today in Nature Medicine, suggest that combining chemotherapy with nerve-protecting agents may prevent long-term bone marrow injury that causes anemia and may improve the success of bone marrow transplants. Contact: Kim Newman Public Release: 5-May-2013
Assembly of a protein degradation machine could lead to treatments in cancer, neurological diseases Scientists discovered new details about an assembly intricate process in cells and the proteins named chaperones that controls it. Their finding may advance treatments for cancer and neurological diseases. Contact: Jeroen Roelofs Public Release: 5-May-2013
Discovery helps show how breast cancer spreads Researchers at Washington University School of Medicine in St. Louis have discovered why breast cancer patients with dense breasts are more likely than others to develop aggressive tumors that spread. The finding opens the door to drug treatments that prevent metastasis. Contact: Julia Evangelou Strait Public Release: 4-May-2013
Toxic waste sites cause healthy years of life lost Toxic waste sites with elevated levels of lead and chromium cause a high number of "healthy years of life lost" in individuals living near 373 sites located in India, Philippines and Indonesia, according to a study by a Mount Sinai researcher published online today in Environmental Health Perspectives. Contact: Renatt Brodsky Public Release: 3-May-2013
'Dark oxidants' form away from sunlight in lake and ocean depths, underground soils Indeed, our bodies aren't perfect. They make mistakes, among them producing toxic chemicals, called oxidants, in cells. We fight these oxidants naturally, and by eating foods rich in antioxidants such as blueberries and dark chocolate. Contact: Cheryl Dybas Public Release: 3-May-2013
Identifying inhibitors of human proteins that promote tumor formation Tumor repressor genes, which inhibit tumor formation, can be "turned off" due to undesirable molecular changes affecting the chromosomes on which the genes reside. Understanding and being able to control these alterations could lead to new approaches for activating or inactivating genes linked to cancer. Contact: Vicki Cohn Public Release: 2-May-2013
Study confirms everolimus can overcome trastuzumab resistance in HER-2 positive early breast cancer A study that aimed to understand how the cancer drug everolimus helps overcome the resistance breast cancers can develop to trastuzumab showed a statistically non-significant benefit in clinical response rates when everolimus is added to trastuzumab. Contact: Vanessa Pavinato Public Release: 2-May-2013
Study opens new prospects for developing new targeted therapies for breast cancer A study led by prominent breast cancer experts from Europe and the US has revealed a number of potentially important prospects for targeted therapies, and brings opportunities of truly personalized therapy for breast cancer a step closer. Contact: Vanessa Pavinato Public Release: 2-May-2013
Study reveals magnitude of variation in gene expression measurements within breast cancers An important new study has revealed the clearest picture yet of precisely how much measurement variation influences gene expression profiles of breast cancer. Contact: Vanessa Pavinato Public Release: 2-May-2013
Genetic and clinical factors best to predict late recurrence in estrogen receptor POS breast cancer A new analysis has provided a comprehensive comparison of scores designed to predict which women with estrogen-receptor positive breast cancer are at high risk of recurrence beyond five years after diagnosis, and may benefit from prolonged endocrine treatment. Contact: Vanessa Pavinato Public Release: 2-May-2013
Gene expression test distinguishes between breast cancer patients at high and low risk of late recurrence A test that measures the expression levels of 58 genes in estrogen receptor-positive breast cancers can effectively differentiate between patients who are at higher and lower risk for having their cancer recur elsewhere in the body more than five years after diagnosis. Contact: Vanessa Pavinato Public Release: 2-May-2013
Breast cancer heterogeneity no barrier to predictive testing, study shows Breast cancers contain many different cell types with different patterns of gene expression, but a new study provides reassurance that this variability should not be a barrier to using gene expression tests to help tailor cancer treatments to individual patients. Contact: Vanessa Pavinato Public Release: 2-May-2013
Focus on STD, not cancer prevention, to promote HPV vaccine use The HPV vaccine can prevent both cervical cancer and a nasty sexually transmitted disease in women. But emphasizing the STD prevention will persuade more young women to get the vaccine. Contact: Janice Krieger Public Release: 2-May-2013
On-site asbestos detector offers promise of better workplace safety Asbestos was once called a miracle material because of its toughness and fire-resistant properties, used as insulation, incorporated into cement and even woven into firemen's protective clothing. Over time, however, scientists pinned the cause of lung cancers such as mesothelioma on asbestos fiber inhalation. Now a team of researchers from the University of Hertfordshire in the UK has developed and tested the first portable, real-time airborne asbestos detector. Contact: Angela Stark Public Release: 2-May-2013
Scientists revolutionize the creation of genetically altered mice to model human disease Using a bacteria-based technique, Whitehead Institute Founding Member Rudolf Jaenisch has efficiently created mouse models with multiple gene mutations in a matter of weeks. Because the method does not require embryonic stem cells, the approach also could allow any animal to become a model organism. Contact: Nicole Rura Public Release: 2-May-2013
DCIS Score quantifies risk of IBE The ductal carcinoma in situ (DCIS) Score quantifies the risk of ipsilateral breast event (IBE) and invasive IBE risk, complements both traditional clinical and pathologic factors, and helps provide a new clinical tool to improve the process of selecting individualized treatment for women with DCIS who meet the criteria, according to a study published May 2 in the Journal of the National Cancer Institute. Contact: Zachary Rathner Public Release: 2-May-2013
CWRU School of Medicine researchers discover new target for personalized cancer therapy A common cancer pathway causing tumor growth is now being targeted by a number of new cancer drugs and shows promising results. A team of researchers at Case Western Reserve University School of Medicine have developed a novel method to disrupt this growth signaling pathway, with findings that suggest a new treatment for breast, colon, melanoma and other cancers. Contact: Christine A. Somosi
Showing releases 76-100 out of 1198. << < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 > >>
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