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Showing releases 76-100 out of 1290.

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Public Release: 2-Feb-2016
eLife
Scientists create imaging 'toolkit' to help identify new brain tumor drug targets
Stopping the growth of blood vessels in tumors is a key target for glioblastoma therapies, and imaging methods are essential for initial diagnosis and monitoring the effects of treatments. A team of researchers have developed a combined magnetic resonance imaging (MRI) and ultramicroscopy 'toolkit' to study vessel growth in glioma models in more detail than previously possible. Their study is to be published in the journal eLife.
CHS Stiftung/CHS Foundation, Medical Faculty of the University of Heidelberg

Contact: Emily Packer
e.packer@elifesciences.org
01-223-855-373
eLife

Public Release: 2-Feb-2016
British Journal of Cancer
Backing from their GP could lead thousands more to take bowel cancer test
Almost 40,000 more people might take a bowel cancer test in England each year if the letter inviting them to do so was endorsed by their GP.

Contact: Fiona
fiona.dennehy@cancer.org.uk
020-346-98300
Cancer Research UK

Public Release: 2-Feb-2016
Nature Immunology
Sharpin emerges from the pack as a regulator of inflammation
it is normal -- in fact necessary -- for our immune system to occasionally fly into an inflammatory rage to defend the host (us) against pathogens or even tumor cells. Problems arise when the rage persists or is re-directed against one's self, as occurs in autoimmune disease.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Jessica Roi
Jroi@lji.org
858-752-6645
La Jolla Institute for Allergy and Immunology

Public Release: 2-Feb-2016
Nature Communications
'Junk' DNA plays role in preventing breast cancer
Supposed "junk" DNA, found in between genes, plays a role in suppressing cancer, according to new research by Universities of Bath and Cambridge.
Cancer Research UK, Cancer Research at Bath, The University of Cambridge, Hutchison Whampoa Limited

Contact: Vicky Just
v.j.just@bath.ac.uk
01-225-386-883
University of Bath

Public Release: 2-Feb-2016
JAMA
Rate of office visits, cumulative costs prior to colonoscopies for colon cancer screening
Kevin R. Riggs, M.D., M.P.H., of the Johns Hopkins University School of Medicine, Baltimore, and colleagues analyzed billing data to determine the proportion of colonoscopies for colon cancer screening and polyp surveillance that were preceded by office visits and the associated payments for those visits. The study appears in the Feb. 2 issue of JAMA.

Contact: Marin Hedin
mhedin2@jhmi.edu
The JAMA Network Journals

Public Release: 2-Feb-2016
Lancet Diabetes & Endocrinology
Height influences risk of cardiovascular disease, diabetes, and cancer
Scientists at the German Center for Diabetes Research (DZD) and the Harvard School of Public Health describe the relationship of the worldwide increase in height with the development of leading chronic non-communicable diseases in the journal The Lancet Diabetes & Endocrinology. Tall people have a lower risk for cardiovascular disease and type 2 diabetes, but a higher risk of cancer. The authors discuss which dietary factors and other mechanisms may explain these associations.

Contact: Dr. Astrid Glaser
glaser@dzd-ev.de
Deutsches Zentrum fuer Diabetesforschung DZD

Public Release: 2-Feb-2016
Autophagy
Autophagy -- a review of techniques
The third edition of 'Guidelines for the use and interpretation of assays for monitoring autophagy' was recently published in the leading journal Autophagy, featuring TGAC's Autophagy Regulatory Network resource and co-authored by Dr. Tamas Korcsmaros, Computational Biology Fellow at The Genome Analysis Centre and Institute of Food Research.

Contact: Hayley London
hayley.london@tgac.ac.uk
01-603-450-107
The Genome Analysis Centre

Public Release: 2-Feb-2016
Proceedings of the National Academy of Sciences
Minority of cancer cells affect the growth and metastasis of tumors
New research shows that a small minority of cancer cells in neuroendocrine tumors of the pancreas contribute to the overall growth and metastasis of the tumor. This discovery was made by a research group at Lund University, in collaboration with researchers at Karolinska Institutet, in Sweden.
Göran and Birgitta Grosskopf, European Research Council, Swedish Cancer Society, Swedish Research Council, and BioCARE

Contact: Cecilia Schubert
cecilia.schubert@kommunikation.lu.se
46-708-661-383
Lund University

Public Release: 1-Feb-2016
Endocrinology
'BPA-free' plastic accelerates embryonic development, disrupts reproductive system
Companies advertise 'BPA-free' as a safer version of plastic products ranging from water bottles to sippy cups to toys. Yet a new UCLA study demonstrates that BPS, a common replacement for BPA, speeds up embryonic development and disrupts the reproductive system. The research is the first to examine the effects of BPA and BPS on key brain cells and genes that control organs involved in reproduction.
UCLA, National Natural Science Foundation of China, Program for Innovative Research Team in University

Contact: Elaine Schmidt
eschmidt@mednet.ucla.edu
310-794-2272
University of California - Los Angeles Health Sciences

Public Release: 1-Feb-2016
Proceedings of the National Academy of Sciences
Shedding new light on breast cancer metastasis
It has long been thought that cancer metastasizes, or spreads, when a single cancer cell escapes from the original tumor, travels through the bloodstream and sets up shop in distant organs. However, a growing body of evidence suggests that these bad actors don't travel alone; instead they migrate through the body in cellular clusters, like gangs.
US Department of Defense, Burroughs Wellcome Fund, American Cancer Society, NIH/National Cancer Institute, Mary Kay Ash Foundation, Cindy Rosencrans Fund for Triple Negative Breast Cancer Research

Contact: Kristen Woodward
kwoodwar@fredhutch.org
206-667-5095
Fred Hutchinson Cancer Research Center

Public Release: 1-Feb-2016
Nature Genetics
Abnormal gene is a triple threat in driving pediatric brain tumors
Oncology researchers have discovered that an abnormal fused gene that drives pediatric brain tumors poses a triple threat, operating simultaneously through three distinct biological mechanisms -- the first such example in cancer biology. This finding potentially offers triple benefits as well -- more accurate diagnoses, clues for more effective treatments and new insights into molecular processes underlying other types of cancer.
National Institutes of Health, A Kids' Brain Tumor Cure Foundation/Pediatric Low-Grade Astrocytoma Foundation, Voices Against Brain Cancer, Thea's Star of Hope, Why Not Me Inc.

Contact: John Ascenzi
Ascenzi@email.chop.edu
267-426-6055
Children's Hospital of Philadelphia

Public Release: 1-Feb-2016
Proceedings of the National Academy of Sciences
Cancer cells travel together to forge 'successful' metastases
There's apparently safety in numbers, even for cancer cells. New research in mice suggests that cancer cells rarely form metastatic tumors on their own, preferring to travel in groups since collaboration seems to increase their collective chances of survival, according to researchers at Johns Hopkins.
US Department of Defense, Burroughs Wellcome Fund, American Cancer Society, NIH/National Cancer Institute, Mary Kay Ash Foundation, Cindy Rosencrans Fund for Triple Negative Breast Cancer Research, Metastatic Breast Cancer Network, and others

Contact: Catherine Gara
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine

Public Release: 1-Feb-2016
European Physical Journal Plus
Physical parameters matter in terms of cancer cells' metastatic ability
The micro-environment surrounding cancer cells is just as important as genes in regulating tumor progression. Scientists have therefore examined the biophysical and biochemical cues occurring in the vicinity of cancer cells. This represents a departure from the traditional measurement of secreted molecules, called biomarkers.

Contact: Sabine Lehr
sabine.lehr@springer.com
49-622-148-78336
Springer

Public Release: 1-Feb-2016
Nature Genetics
Genetic cause identified in rare pediatric brain tumor
Researchers found a way of differentiating angiocentric gliomas from other low-grade pediatric brain tumors and developed a pathological test that will help children avoid unnecessary and potentially damaging additional therapies.
A Kids' Brain Tumor Cure Foundation Pediatric Low-Grade Astrocytoma Foundation, National Institutes of Health

Contact: Teresa Herbert
teresa_herbert@dfci.harvard.edu
617-632-4090
Dana-Farber Cancer Institute

Public Release: 1-Feb-2016
Gut
10-fold difference worldwide in new cases of, and deaths from, bowel cancer
There's a 10-fold difference worldwide in the numbers of new cases of bowel cancer and deaths from the disease, finds research published online in the journal Gut.

Contact: Caroline White
CWhite@bmj.com
44-798-080-0465
BMJ

Public Release: 1-Feb-2016
Journal of Clinical Oncology
Does radiation therapy improve survival for women with ductal carcinoma in situ?
Investigators from Brigham and Women's Hospital (BWH) and the Dana-Farber Cancer Institute have found that a set of easily measurable risk factors can predict the magnitude of survival benefit offered by radiation therapy following breast cancer surgery. Their results appear online in The Journal of Clinical Oncology on Feb. 1.
National Institutes of Health

Contact: Haley Bridger
hbridger@partners.org
617-525-6383
Brigham and Women's Hospital

Public Release: 1-Feb-2016
Journal of Women's Health
Preventing cardiovascular disease in women -- one physician's approach to juggling the many guidelines
Nanette K. Wenger, M.D., Professor of Medicine (Cardiology) Emeritus, Emory University School of Medicine, provides a comprehensive perspective on how to apply the many new and continuously updated guidelines for preventing cardiovascular disease (CVD) and reducing CVD risk factors in women, in a clear and concise review article published in Journal of Women's Health.

Contact: Kathryn Ryan
kryan@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 1-Feb-2016
Proceedings of the National Academy of Sciences
A 'gap in the armor' of DNA may allow enzyme to trigger cancer-causing mutations
Research from Indiana University published in the Proceedings of the National Academy of Sciences has identified a genetic mechanism that is likely to drive mutations that can lead to cancer.
US Army Research Office, National Institutes of Health

Contact: Kevin D. Fryling
kfryling@iu.edu
812-856-2988
Indiana University

Public Release: 1-Feb-2016
Computers, Informatics, Nursing
When loved ones battle cancer, families head to Web for information more than support
Loved ones of cancer patients are likely to search for further information about the disease online but less inclined to seek emotional support from social media forums, according to a University of Georgia study. It is fairly common for loved ones of cancer patients to develop depression or anxiety disorders, but there aren't many studies focusing specifically on cancer patients' caregivers and family members, said the study's author, Carolyn Lauckner.
Michigan State University's College of Communication Arts and Sciences

Contact: Stephanie Schupska
schupska@uga.edu
706-542-6927
University of Georgia

Public Release: 1-Feb-2016
Cancer Research
Turning down the volume on cancer
When the audio on your television set is too loud, you simply turn down the volume. What if we could do the same for signaling in our bodies that essentially causes normal cells to turn cancerous? New discoveries by researchers at the Stephenson Cancer Center at the University of Oklahoma may point to ways to do just that. Hiroshi Y. Yamada, Ph.D., and his team identified previously unknown targets for colon cancer prevention and treatment.
NIH/National Cancer Institute, Chris4Life Colon Cancer Foundation, NIH/National Center for Research Resources, NIH/National Institute of General Medical Sciences

Contact: Theresa Green
theresa-green@ouhsc.edu
405-833-9824
University of Oklahoma

Public Release: 1-Feb-2016
Cell Reports
Researchers identify potential targeted therapy for lung cancer using fly model
A drug approved by the Food and Drug Administration for melanoma in combination with a common cholesterol-lowering drug may show promise in controlling cancer growth in patients with non-small cell lung cancer, according to new research from the Icahn School of Medicine at Mount Sinai.
National Institutes of Health

Contact: Lucia Lee
newsmedia@mssm.edu
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 1-Feb-2016
Obstetrics & Gynecology
Sparing ovaries and removing fallopian tubes may cut cancer risk, but few have procedure
During hysterectomies for non-cancerous conditions, removing both fallopian tubes while keeping the ovaries may help protect against ovarian cancer and preserve hormonal levels, but few women receive this surgical option, according to a new study by Yale School of Medicine researchers.

Contact: Karen N. Peart
karen.peart@yale.edu
203-432-1326
Yale University

Public Release: 1-Feb-2016
Americans favor a tax increase to support the 'moonshot' cancer initiative
Vice President Joe Biden's 'moonshot' initiative to defeat cancer earns support for a tax increase to fund cancer research among half of respondents (50 percent) in a new national public opinion survey commissioned by Research!America. Thirty-eight percent disagree and an additional 12 percent are not sure. A significant majority of Democrats (67 percent), and more than a third of Republicans (38 percent) and Independents (39 percent) support a tax increase, and support is particularly strong among Americans ages 18 - 49.

Contact: Anna Briseno
abriseno@researchamerica.org
571-482-2737
Research!America

Public Release: 1-Feb-2016
British Journal of Pharmacology
Cancer drug helps combat asthma in mice
In a mouse model of allergic asthma, dasatinib -- an enzyme inhibitor approved for the treatment of chronic myelogenous leukemia -- reduced inflammation, enhanced airway repair, and improved lung mechanics.

Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley

Public Release: 1-Feb-2016
BJU International
Targeted antibiotics may help protect against infections in men being tested for prostate cancer
A new review indicates that antimicrobial therapy given before clinicians take transrectal ultrasound-guided prostate biopsies to diagnose prostate cancer may lead to lower rates of sepsis, a potentially life-threatening infection.

Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley

Showing releases 76-100 out of 1290.

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