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Public Release: 19-Aug-2016
Therapeutic Advances in Gastroenterology
MRI technology quantifies liver response in nonalcoholic steatohepatitis patients
Researchers at the University of California San Diego School of Medicine have found that a form of magnetic resonance imaging (MRI) that non-invasively measures fat density in the liver corresponds with histological (microscopic tissue analyses) responses in patients with nonalcoholic steatohepatitis (NASH).
Atlantic Philanthropies, Inc., John A. Hartford Foundation, Association of Specialty Professors, American Gastroenterological Association and National Institutes of Health

Contact: Scott LaFee
slafee@ucsd.edu
858-249-0456
University of California - San Diego

Public Release: 19-Aug-2016
Cancer Epidemiology, Biomarkers & Prevention
Parents more likely to support HPV vax requirements if states include opt-out provisions
Parents are more likely to support laws that would make the human papillomavirus vaccine mandatory for school entry if their state offers opt-out provisions, however, the study's lead author cautioned that such opt-out provisions may weaken the effectiveness of the vaccine requirements.
Merck Sharp & Dohme Investigator Studies Program

Contact: Lauren Riley
lauren.riley@aacr.org
215-446-7155
American Association for Cancer Research

Public Release: 19-Aug-2016
Cancer Epidemiology, Biomarkers & Prevention
Majority of parents support HPV vaccination requirements for school, but with opt-outs
A national survey found that parents were more likely to agree that laws requiring students to be vaccinated against HPV for school entry are a 'good idea' when there is an opt-out clause. This provision, said the University of North Carolina researchers, could make the laws far less effective. It also means physicians and other health care providers are key to improving HPV vaccination rates.
Merck Sharp & Dohme Investigator Studies Program, NIH/National Cancer Institute

Contact: Bill Schaller
bill_schaller@med.unc.edu
919-962-3405
UNC Lineberger Comprehensive Cancer Center

Public Release: 19-Aug-2016
Scientific Reports
Increased eye cancer risk linked to pigmentation genes that dictate eye color
New research links specific inherited genetic differences to an increased risk for eye (uveal) melanoma, a rare form of melanoma that arises from pigment cells that determine eye color. scientists report the first evidence of a strong association between genes linked to eye color and development of uveal melanoma. Reported data suggests that inherited genetic factors associated with eye and skin pigmentation could increase a person's risk for uveal melanoma.
NIH/National Cancer Institute, NIH/National Eye Institute

Contact: Amanda Harper
amanda.harper2@osumc.edu
614-685-5420
Ohio State University Wexner Medical Center

Public Release: 19-Aug-2016
Nature Communications
'Born to be bad' or 'born to be benign' -- testing cells for esophageal cancer risk
Genetically analyzing lesions in the food pipe could provide an early and accurate test for esophageal cancer, according to research led by Queen Mary University of London, Academic Medical Center in Amsterdam and Arizona State University.

Contact: Joel Winston
j.winston@qmul.ac.uk
Queen Mary University of London

Public Release: 18-Aug-2016
PLOS ONE
Moffitt study highlights importance of regular lung cancer screenings for those at high risk
A new study by researchers at Moffitt Cancer Center found patients who tested negative for lung cancer by a detailed X-ray screening called low-dose helical computed tomography but later went on to develop lung cancer within the following two years had poorer outcomes than patients who initially had a non-cancerous positive LDCT screen.

Contact: Steve Blanchard
steve.blanchard@moffitt.org
813-745-1718
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 18-Aug-2016
Cogent Psychology
Face changing technology showing sun damage is most effective at promoting sun safe behavior
Researchers from the University of Surrey examined the way sun safe messages are conveyed to young women, and found that visual communication using technology to age participant's faces to emphasis sun damage and premature aging is most effective.

Contact: Peter La
p.la@surrey.ac.uk
44-148-368-9191
University of Surrey

Public Release: 18-Aug-2016
JAMA Oncology
Rates of early prostate cancer continue decline after USPSTF recommendation
Incidence rates of early prostate cancer have continued to drop since the US Preventive Services Task Force recommendation against routine prostate-specific antigen (PSA) testing in all men, according to an article published online by JAMA Oncology.

Contact: David Sampson
david.sampson@cancer.org
The JAMA Network Journals

Public Release: 18-Aug-2016
Journal of the American College of Radiology
New report presents bundled payment model for breast cancer screening
According to a new report by the Harvey L. Neiman Health Policy Institute, mammography may present an opportunity for the expanded use of bundled payments in radiology. The study, published online in the Journal of the American College of Radiology, reports that breast cancer screening provides a framework for radiologist-led bundled payment models, and can be implemented with different services included in the bundle depending upon a practice's specific patient panel.

Contact: Nicole Racadag
nracadag@neimanhpi.org
703-716-7559
Harvey L. Neiman Health Policy Institute

Public Release: 18-Aug-2016
International Journal of Cancer
Natural compound from a deep-water marine sponge found to reduce pancreatic tumor size
A deep-water marine sponge collected off of Fort Lauderdale's coast contains leiodermatolide, a natural product that has the ability to inhibit the growth of cancer cells as well as block cancer cells from dividing using extremely low concentrations of the compound. Sea sponges are an ancient group of animals that appeared more than 600 million years ago that have many of the same genes as humans.
National Institutes of Health, State of Florida Center of Excellence in Biomedical & Marine Biotechnology, National Oceanic and Atmospheric Administration

Contact: Gisele Galoustian
ggaloust@fau.edu
561-297-2676
Florida Atlantic University

Public Release: 18-Aug-2016
Gastroenterology
Not all tumor cells are equal
Scientists led by Dr. Manel Esteller find that colorectal tumors present epigenetic heterogeneity relates to the clinical course of the disease. This heterogeneity can be used as a predictive biomarker.

Contact: Gemma Fornons
gfornons@idibell.cat
34-638-685-074
IDIBELL-Bellvitge Biomedical Research Institute

Public Release: 18-Aug-2016
Cell
Nobel laureate, new technologies show how cancer cells protect chromosomes from decay
Nobel laureate and University of Colorado Cancer Center investigator, Thomas Cech, PhD, uses CRISPR gene editing technology and live cell, single molecule microscopy to watch in real-time, for the first time, the essential interaction between telomerase and telomeres.
National Institutes of Health, Damon Runyon Cancer Research Foundation

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Anschutz Medical Campus

Public Release: 18-Aug-2016
Structure
First 3-D map of cell-building protein linked to cancer
Walter and Eliza Hall Institute researchers have revealed for the first time the three-dimensional molecular 'map' of a protein that has been pinpointed as a driver of many types of cancers.
Australian Research Council, Australian Cancer Research Foundation, National Health and Medical Research Council and the Victorian Government Operational Infrastructure Support Scheme

Contact: Vanessa S Solomon
solomon@wehi.edu.au
61-431-766-715
Walter and Eliza Hall Institute

Public Release: 18-Aug-2016
Cell Stem Cell
Penn team identifies strategy to reverse the disease dyskeratosis congenita
In a new study published in Cell Stem Cell, researchers from the University of Pennsylvania led by Christopher J. Lengner of the School of Veterinary Medicine and Brad Johnson of the Perelman School of Medicine have found a link between telomeres and a molecular signaling cascade called the Wnt pathway that may point to a treatment option for dyskeratosis congenita patients.
NIH/National Institute on Aging, NIH/National Institute of Diabetes and Digestive and Kidney Disorders, NIH/National Cancer Institute

Contact: Katherine Unger Baillie
kbaillie@upenn.edu
215-898-9194
University of Pennsylvania

Public Release: 18-Aug-2016
PLOS Pathogens
Fruit flies could be key to fighting cervical cancer caused by human papillomavirus
HPV is one of the most common sexually transmitted infections in the US and has been identified as a cause of cancer in women. A team of researchers led by the University of Missouri has completed studies on fruit flies with a condition that mimics a form of HPV-induced cancer. The fly models they developed may help scientists understand the underlying mechanism by which HPV can cause cancer. The study appears in PLoS Pathogens.
National Institutes of Health

Contact: Jeff Sossamon
sossamonj@missouri.edu
573-882-3346
University of Missouri-Columbia

Public Release: 18-Aug-2016
Behavioral Brain Research
Study confirms long-term effects of 'chemobrain' in mice
Women undergoing chemotherapy for breast cancer have long complained of lingering cognitive impairments after treatment. These effects are referred to as 'chemobrain,' a feeling of mental fogginess. A new study from the University of Illinois reports long-lasting cognitive impairments in mice when they are administered a chemotherapy regimen used to treat breast cancer in humans.

Contact: Sarah Banducci
diya@illinois.edu
217-333-5802
University of Illinois at Urbana-Champaign

Public Release: 18-Aug-2016
American Journal of Roentgenology
Osteoblastic metastases distinguished from enostoses using CT attenuation measurements
A team of Boston researchers found that CT attenuation measurements can be used to distinguish untreated osteoblastic (bone-related) metastases from enostoses (benign bone lesions).

Contact: Kimberly Coghill
kcoghill@arrs.org
703-858-4332
American Roentgen Ray Society

Public Release: 18-Aug-2016
JAMA Oncology
How genomic sequencing may be widening racial disparities in cancer care
As scientists learn more about which genetic mutations are driving different types of cancer, they're targeting treatments to small numbers of patients with the potential for big payoffs in improved outcomes. But even as we learn more about these driver mutations, a new study suggests the science might be leaving racial and ethnic minorities behind.
NIH/National Cancer Institute, Prostate Cancer Foundation

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 17-Aug-2016
Journal of Molecular Diagnostics
New standard helps ensure accurate clinical measurements of HER2 breast cancer gene
Study demonstrates value of new measurement reference for both evaluating assay performance and increasing confidence in reporting HER2 amplification for clinical applications.

Contact: Mark Bello
mark.bello@nist.gov
301-975-3776
National Institute of Standards and Technology (NIST)

Public Release: 17-Aug-2016
Blood
Leukaemia blood testing has 'massive potential'
Researchers at The University of Manchester have unlocked the potential of a new test which could revolutionise the way doctors diagnose and monitor a common childhood Leukaemia.
Bloodwise, Cancer Research UK, European Union's Seventh Framework Programme

Contact: Jamie Brown
jamie.brown@manchester.ac.uk
44-161-275-8383
University of Manchester

Public Release: 17-Aug-2016
Journal of Molecular Diagnostics
Association for molecular pathology establishes new standard for clinical utility of molecular Dx
The Association for Molecular Pathology, the premier global, non-profit organization serving molecular diagnostic professionals, today announced a new report that addresses the challenges in defining the clinical utility of molecular diagnostics for inherited diseases and cancer. The manuscript titled 'The Spectrum of Clinical Utilities in Molecular Pathology Testing Procedures for Inherited Conditions and Cancer: A Report of the Association for Molecular Pathology' has been released online ahead of publication in the Sept. 2016 issue of The Journal of Molecular Diagnostics.
Association for Molecular Pathology

Contact: Andrew Noble
anoble@amp.org
415-722-2129
Association for Molecular Pathology

Public Release: 17-Aug-2016
Biomaterials
Lab team spins ginger into nanoparticles to heal inflammatory bowel disease
Researchers with the Department of Veterans Affairs and the Institute for Biomedical Sciences at Georgia State University have developed 'edible ginger-derived nanoparticles' that they believe may be good medicine for Crohn's disease and ulcerative colitis, the two main forms of inflammatory bowel disease. The particles may also help fight cancer linked to colitis, according to experiments in mice.
US Department of Veterans Affairs, National Institutes of Health, Crohn's and Colitis Foundation of America

Contact: Greg Kendall
Gregory.Kendall@va.gov
404-417-5385
Veterans Affairs Research Communications

Public Release: 17-Aug-2016
Journal of Nuclear Medicine
Novel tracer safely and effectively maps sentinel lymph nodes in breast cancer patients
A recent study by researchers at Peking University Cancer Hospital & Institute demonstrates the effectiveness and safety of Tc-99m-rituximab, a new SLN radiotracer, that targets the antigen CD20, which is expressed extensively in lymph nodes. The study is published in the August issue of the Journal of Nuclear Medicine.
National Natural Science Foundation of China, Beijing Natural Science Foundation, Beijing Municipal Commission of Health and Family Planning

Contact: Laurie Callahan
lcallahan@snmmi.org
Society of Nuclear Medicine

Public Release: 17-Aug-2016
Nature Communications
Isotope research opens new possibilities for cancer treatment
A new study at Los Alamos National Laboratory and in collaboration with Stanford Synchrotron Radiation Lightsource greatly improves scientists' understanding of the element actinium. The insights could support innovation in creating new classes of anticancer drugs.

Contact: Nancy Ambrosiano
nwa@lanl.gov
505-667-0471
DOE/Los Alamos National Laboratory

Public Release: 17-Aug-2016
Cochrane Library
Music demonstrated to alleviate cancer patients' symptoms
A review looking at studies on the effect music interventions have on the treatment of cancer patients found treatment benefits for anxiety, pain, fatigue and overall quality of life.
Drexel University, State of Pennsylvania Formula Fund

Contact: Frank Otto
fmo26@drexel.edu
215-571-4244
Drexel University

Showing releases 76-100 out of 1391.

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