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Showing releases 76-100 out of 1198.

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Public Release: 6-May-2013
Journal of Cell Biology
Wip1 could be new target for cancer treatment
Researchers have uncovered mutations in the phosphatase Wip1 that enable cancer cells to foil the tumor suppressor p53, according to a study in The Journal of Cell Biology. The results could provide a new target for the treatment of certain cancers.

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press

Public Release: 6-May-2013
Pediatric Academic Societies Annual Meeting
Children living near toxic waste sites experience higher blood lead levels resulting in lower IQ
Children living near toxic waste sites in lower and middle income countries such as India, Philippines and Indonesia may experience higher blood lead levels, resulting in a loss of IQ points and a higher incidence of mental retardation, according to a study presented today by Kevin Chatham-Stephens, M.D., Pediatric Environmental Health Fellow at the Icahn School of Medicine at Mount Sinai, at the Pediatric Academic Societies annual meeting on May 6 in Washington, DC.
Blacksmith Institute

Contact: Renatt Brodsky
Renatt.Brodsky@mountsinai.org
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 6-May-2013
93rd American Association for Thoracic Surgery Annual Meeting
Minimal dose CT superior to chest X-ray for detection of recurrent lung cancer
In this study presented at the 93rd AATS Annual Meeting, investigators from the University of Toronto departments of Thoracic Surgery and Diagnostic Radiology show that minimal dose computed tomography of the thorax offers much greater sensitivity at detecting new or recurrent lung cancer, with equivalent amount of radiation, compared to conventional chest X-rays.

Contact: Nicole Baritot
press@aats.org
978-299-4520
American Association for Thoracic Surgery

Public Release: 6-May-2013
The Lancet
New class of drug targets skin cancer
A new class of drug targeting skin cancer's genetic material has been successfully tested in humans for the first time, opening the way to new treatments for a range of conditions from skin cancers to eye diseases.
National Health and Medical Research Council, Australia

Contact: Susi Hamilton
susi.hamilton@unsw.edu.au
61-422-934-024
University of New South Wales

Public Release: 6-May-2013
Oncogene
Activity of cancer inducing genes can be controlled by the cell's skeleton
In the latest issue of the journal Oncogene, Florence Janody and her team at the Instituto Gulbenkian de Ciência, identified a novel mechanism by which the activity of Src is limited by the cell's skeleton, limiting the development of tumors.
Fundação para a Ciência e a Tecnologia (Portugal)

Contact: Inês Domingues
idomingues@igc.gulbenkian.pt
351-214-464-642
Instituto Gulbenkian de Ciencia

Public Release: 5-May-2013
AUA Annual Meeting 2013
Some prostate cancer patients more likely to die after weekend ER visits
Patients with prostate cancer that has metastasized, or spread, to other parts of the body face a significantly higher risk of dying when visiting a hospital emergency department on the weekend instead of on a weekday, according to researchers at Henry Ford Hospital in Detroit.

Contact: Dwight Angell
dwight.angell@hfhs.org
313-850-3471
Henry Ford Health System

Public Release: 5-May-2013
AUA Annual Meeting 2013
Hospital surgical volume should be considered when judging value of procedures
The volume of cases performed at an institution each year has a direct effect on the outcome of surgical procedures, and should always be considered when looking at the benefits of a technique, according to a team of researchers at Henry Ford Hospital in Detroit.
Vattikuti Urology Institute

Contact: Dwight Angell
dwight.angell@hfhs.org
313-850-3471
Henry Ford Health System

Public Release: 5-May-2013
Nature Genetics
Protein complex may play role in preventing many forms of cancer, Stanford study shows
Researchers at the Stanford University School of Medicine have identified a group of proteins that are mutated in about one-fifth of all human cancers. The finding suggests that the proteins, which are members of a protein complex that affects how DNA is packaged in cells, work to suppress the development of tumors in many types of tissues.

Contact: Krista Conger
kristac@stanford.edu
650-725-5371
Stanford University Medical Center

Public Release: 5-May-2013
Nature Medicine
Discovery may help prevent chemotherapy-induced anemia
Researchers at Albert Einstein College of Medicine have discovered that chemotherapy induces an insidious type of nerve damage inside bone marrow that can cause delays in recovery after bone marrow transplantation. The findings, made in mice and published online today in Nature Medicine, suggest that combining chemotherapy with nerve-protecting agents may prevent long-term bone marrow injury that causes anemia and may improve the success of bone marrow transplants.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, NIH/National Heart, Lung, and Blood Institute

Contact: Kim Newman
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine

Public Release: 5-May-2013
Nature
Assembly of a protein degradation machine could lead to treatments in cancer, neurological diseases
Scientists discovered new details about an assembly intricate process in cells and the proteins named chaperones that controls it. Their finding may advance treatments for cancer and neurological diseases.

Contact: Jeroen Roelofs
jroelofs@k-state.edu
785-532-3969
Kansas State University

Public Release: 5-May-2013
Nature Cell Biology
Discovery helps show how breast cancer spreads
Researchers at Washington University School of Medicine in St. Louis have discovered why breast cancer patients with dense breasts are more likely than others to develop aggressive tumors that spread. The finding opens the door to drug treatments that prevent metastasis.
National Institutes of Health, Susan G. Komen for the Cure

Contact: Julia Evangelou Strait
straitj@wustl.edu
314-286-0141
Washington University School of Medicine

Public Release: 4-May-2013
Pediatric Academic Societies Annual Meeting
Environmental Health Perspectives
Toxic waste sites cause healthy years of life lost
Toxic waste sites with elevated levels of lead and chromium cause a high number of "healthy years of life lost" in individuals living near 373 sites located in India, Philippines and Indonesia, according to a study by a Mount Sinai researcher published online today in Environmental Health Perspectives.
Blacksmith Institute

Contact: Renatt Brodsky
Renatt.Brodsky@mountsinai.org
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 3-May-2013
Science Express
'Dark oxidants' form away from sunlight in lake and ocean depths, underground soils
Indeed, our bodies aren't perfect. They make mistakes, among them producing toxic chemicals, called oxidants, in cells. We fight these oxidants naturally, and by eating foods rich in antioxidants such as blueberries and dark chocolate.
National Science Foundation

Contact: Cheryl Dybas
cdybas@nsf.gov
703-292-7734
National Science Foundation

Public Release: 3-May-2013
ASSAY and Drug Development Technologies
Identifying inhibitors of human proteins that promote tumor formation
Tumor repressor genes, which inhibit tumor formation, can be "turned off" due to undesirable molecular changes affecting the chromosomes on which the genes reside. Understanding and being able to control these alterations could lead to new approaches for activating or inactivating genes linked to cancer.

Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2100 x2156
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 2-May-2013
5th IMPAKT Breast Cancer Conference
Annals of Oncology
Study confirms everolimus can overcome trastuzumab resistance in HER-2 positive early breast cancer
A study that aimed to understand how the cancer drug everolimus helps overcome the resistance breast cancers can develop to trastuzumab showed a statistically non-significant benefit in clinical response rates when everolimus is added to trastuzumab.

Contact: Vanessa Pavinato
media@esmo.org
European Society for Medical Oncology

Public Release: 2-May-2013
5th IMPAKT Breast Cancer Conference
Annals of Oncology
Study opens new prospects for developing new targeted therapies for breast cancer
A study led by prominent breast cancer experts from Europe and the US has revealed a number of potentially important prospects for targeted therapies, and brings opportunities of truly personalized therapy for breast cancer a step closer.

Contact: Vanessa Pavinato
media@esmo.org
European Society for Medical Oncology

Public Release: 2-May-2013
5th IMPAKT Breast Cancer Conference
Annals of Oncology
Study reveals magnitude of variation in gene expression measurements within breast cancers
An important new study has revealed the clearest picture yet of precisely how much measurement variation influences gene expression profiles of breast cancer.

Contact: Vanessa Pavinato
media@esmo.org
European Society for Medical Oncology

Public Release: 2-May-2013
5th IMPAKT Breast Cancer Conference
Annals of Oncology
Genetic and clinical factors best to predict late recurrence in estrogen receptor POS breast cancer
A new analysis has provided a comprehensive comparison of scores designed to predict which women with estrogen-receptor positive breast cancer are at high risk of recurrence beyond five years after diagnosis, and may benefit from prolonged endocrine treatment.

Contact: Vanessa Pavinato
media@esmo.org
European Society for Medical Oncology

Public Release: 2-May-2013
5th IMPAKT Breast Cancer Conference
Annals of Oncology
Gene expression test distinguishes between breast cancer patients at high and low risk of late recurrence
A test that measures the expression levels of 58 genes in estrogen receptor-positive breast cancers can effectively differentiate between patients who are at higher and lower risk for having their cancer recur elsewhere in the body more than five years after diagnosis.

Contact: Vanessa Pavinato
media@esmo.org
European Society for Medical Oncology

Public Release: 2-May-2013
5th IMPAKT Breast Cancer Conference
Annals of Oncology
Breast cancer heterogeneity no barrier to predictive testing, study shows
Breast cancers contain many different cell types with different patterns of gene expression, but a new study provides reassurance that this variability should not be a barrier to using gene expression tests to help tailor cancer treatments to individual patients.

Contact: Vanessa Pavinato
media@esmo.org
European Society for Medical Oncology

Public Release: 2-May-2013
Health Communication
Focus on STD, not cancer prevention, to promote HPV vaccine use
The HPV vaccine can prevent both cervical cancer and a nasty sexually transmitted disease in women. But emphasizing the STD prevention will persuade more young women to get the vaccine.

Contact: Janice Krieger
Raup-krieger.1@osu.edu
614-342-0330
Ohio State University

Public Release: 2-May-2013
Optics Express
On-site asbestos detector offers promise of better workplace safety
Asbestos was once called a miracle material because of its toughness and fire-resistant properties, used as insulation, incorporated into cement and even woven into firemen's protective clothing. Over time, however, scientists pinned the cause of lung cancers such as mesothelioma on asbestos fiber inhalation. Now a team of researchers from the University of Hertfordshire in the UK has developed and tested the first portable, real-time airborne asbestos detector.

Contact: Angela Stark
astark@osa.org
202-416-1443
The Optical Society

Public Release: 2-May-2013
Cell
Scientists revolutionize the creation of genetically altered mice to model human disease
Using a bacteria-based technique, Whitehead Institute Founding Member Rudolf Jaenisch has efficiently created mouse models with multiple gene mutations in a matter of weeks. Because the method does not require embryonic stem cells, the approach also could allow any animal to become a model organism.
National Institutes of Health, Damon Runyon Cancer Research Foundation, Croucher Foundation

Contact: Nicole Rura
rura@wi.mit.edu
617-258-6851
Whitehead Institute for Biomedical Research

Public Release: 2-May-2013
Journal of the National Cancer Institute
DCIS Score quantifies risk of IBE
The ductal carcinoma in situ (DCIS) Score quantifies the risk of ipsilateral breast event (IBE) and invasive IBE risk, complements both traditional clinical and pathologic factors, and helps provide a new clinical tool to improve the process of selecting individualized treatment for women with DCIS who meet the criteria, according to a study published May 2 in the Journal of the National Cancer Institute.

Contact: Zachary Rathner
Zachary.Rathner@oup.com
919-677-2697
Journal of the National Cancer Institute

Public Release: 2-May-2013
Cancer Cell
CWRU School of Medicine researchers discover new target for personalized cancer therapy
A common cancer pathway causing tumor growth is now being targeted by a number of new cancer drugs and shows promising results. A team of researchers at Case Western Reserve University School of Medicine have developed a novel method to disrupt this growth signaling pathway, with findings that suggest a new treatment for breast, colon, melanoma and other cancers.

Contact: Christine A. Somosi
christine.somosi@case.edu
216-368-6287
Case Western Reserve University

Showing releases 76-100 out of 1198.

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