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Public Release: 11-Jan-2016
Annals of Internal Medicine
Making a safe procedure even safer
In a comprehensive modeling study, researchers from UC Davis and other institutions have found that breast cancer screening with digital mammography poses only a small risk of radiation-induced breast cancer for most women.
Agency for Healthcare Research and Quality, NIH/National Cancer Institute

Contact: Dorsey Griffith
University of California - Davis Health System

Public Release: 11-Jan-2016
Annals of Internal Medicine
More research needed on evaluation of dense breasts
A systematic review of the scientific literature on dense breasts by researchers at UC Davis and other institutions has found that determinations of breast density can be unreliable and that as many as 19 percent of women are re-categorized as dense rather than non-dense or vice versa from one mammogram to the next.
Agency for Healthcare Research and Quality

Contact: Dorsey Griffith
University of California - Davis Health System

Public Release: 11-Jan-2016
Cancer Cell
McMaster researchers reveal predictive staircase to leukemia
In the paper published today by the scientific journal Cancer Cell, the researchers detail how they have been able to fingerprint myelodysplastic syndromes, a state for blood cells that turns into acute myeloid leukemia cancer in approximately 30 percent of patients.
Canadian Institutes of Health Research, Canadian Cancer Society Research Institute

Contact: Veronica McGuire
McMaster University

Public Release: 11-Jan-2016
Annals of Internal Medicine
USPSTF final recommendations on breast cancer screening
The US Preventive Services Task Force published a final recommendation statement on screening for breast cancer following an in-depth review of the science on the benefits and harms of screening mammography, and a detailed review of input received from the public and health care professionals on its 2015 draft recommendation.

Contact: Cara Graeff
American College of Physicians

Public Release: 11-Jan-2016
Future of lung treatment: Malaysian scientists join Harvard team creating safe, effective nano drugs
Scientists from Malaysia are teaming with Harvard University experts to help revolutionize the treatment of lung diseases -- the safe, effective delivery of nanomedicine deep into parts of the lung unreachable using common inhalers. Other Malaysian Institute for Innovative Nanotechnology research pursuits include converting greenhouse gases into an energy source; 'Smart farming' nanosensors; more. The new national nanotech program, initiated through Malaysia's Global Science & Innovation Advisory Council, aims to make a macro impact in health, energy, environment, agriculture, electronics.

Contact: Terry Collins
Malaysian Industry-Government Group for High Technology

Public Release: 11-Jan-2016
What's in store for survivors of childhood cancers that affect vision?
Little is known about the long-term health of survivors of childhood cancers that affect vision, but two new studies provide valuable insights that could impact patient care and follow-up. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

Contact: Dawn Peters

Public Release: 11-Jan-2016
Proceedings of the National Academy of Sciences
PNAS: Childhood leukemias forged by different evolutionary forces than in older adults
A University of Colorado Cancer Center paper published in the Proceedings of the National Academy of Sciences shows that the evolutionary force of genetic drift contributes to the ability of cancerous cells to overtake populations of healthy cells in young children. In contrast, genetic drift contributes almost not at all to leukemia formation in adults. The finding suggests important new avenues for leukemia treatment in very young patients.
NIH/National Cancer Institute, Linda Crnic Institute for Down Syndrome, Leukemia Lymphoma Society, St. Baldrick's Foundation

Contact: Garth Sundem
University of Colorado Anschutz Medical Campus

Public Release: 11-Jan-2016
Public Health Reports
One hookah tobacco smoking session delivers 25 times the tar of a single cigarette
As cigarette smoking rates fall, more people are smoking tobacco from hookahs -communal pipes that enable users to draw tobacco smoke through water. A new meta-analysis led by the University of Pittsburgh School of Medicine shows that hookah smokers are inhaling a large load of toxicants.
NIH/National Cancer Institute

Contact: Allison Hydzik
University of Pittsburgh Schools of the Health Sciences

Public Release: 11-Jan-2016
Biotech Showcase
InSilico Medicine presents advances in deep learning for drug discovery and aging research
On Tuesday, Jan. 12, at 5:15 p.m. US ET, InSilico Medicine will present an update on recent advances in applying signaling pathway activation analysis and deep learning to drug discovery and drug repurposing for age-related diseases at the Biotech Showcase in San Francisco.

Contact: Qingsong Zhu
InSilico Medicine, Inc.

Public Release: 11-Jan-2016
Annals of Internal Medicine
New analyses confirms biennial mammography starting at age 50 is optimal for average women
New and comprehensive analyses from six independent research teams examining breast cancer screening intervals have produced a unanimous finding -- that mammography screening every two years for average risk women ages 50 to 74 offers a favorable balance of benefits to harm.
National Institutes of Health

Contact: Karen Teber
Georgetown University Medical Center

Public Release: 11-Jan-2016
Nature Methods
Linking gene expression and DNA methylation in single cells
A new single-cell genomics protocol allows researchers to study links between DNA modifications (methylation) and the activity of a gene. The method is the first to enable parallel profiling of the transcriptome and epigenome of a single cell. The researchers used the method to reveal new epigenome-transcriptome associations relevant to the regulation of pluripotency in mouse embryonic stem cells; The method is potentially transformative for epigenetics research, as it reveals unprecedented detail of the epigenetic control of genes.
Biotechnology and Biological Sciences Research Council, Wellcome Trust, European Molecular Biology Laboratory, Medical Research Council, European Commission

Contact: Mary Todd Bergman
European Molecular Biology Laboratory - European Bioinformatics Institute

Public Release: 11-Jan-2016
Painkiller tapped to become future cancer-killer
Diclofenac, a common painkiller, has significant anti-cancer properties, according to researchers from the Repurposing Drugs in Oncology project. Like other drugs examined by the ReDO project, diclofenac is cheap and readily accessible -- and as it's already present in many medicine cabinets, it has been carefully tested.

Contact: Audrey Nailor

Public Release: 10-Jan-2016
2016 Genitourinary Cancers Symposium
Even after anti-androgen therapy, docetaxel remains useful in prostate cancer
A study presented at the 2016 Genitourinary Cancers Symposium shows that 40 percent of patients with castration-resistant metastatic prostate cancer (mCRPC) treated with docetaxel following abiraterone had at least 50 percent reduction in prostate specific antigen (PSA), demonstrating the activity of this drug sequencing.
Genitourinary Cancers Symposium 2016

Contact: Garth Sundem
University of Colorado Anschutz Medical Campus

Public Release: 8-Jan-2016
New report finds no significant increase in health risks for 1960s Project SHAD veterans
Veterans who participated in a series of tests during the 1960s known as Project SHAD (Shipboard Hazard and Defense) show no significant increase in adverse health outcomes, specific causes of death, or death rates compared with a similar group of veterans who were not involved in the tests, says a new report from a committee of the National Academies of Sciences, Engineering, and Medicine.

Contact: Molly Galvin
National Academy of Sciences

Public Release: 8-Jan-2016
Mutation Research/Genetic Toxicology and Environmental Mutagenesis
BRCA1 deficiency increases the sensitivity of ovarian cancer cells to auranofin
An anti-rheumatic drug could improve the prognosis for ovarian cancer patients exhibiting a deficiency of the DNA repair protein BRCA1, a study led by Plymouth University has found.

Contact: Alan Williams
University of Plymouth

Public Release: 8-Jan-2016
Science Advances
Scientists find key driver for treatment of deadly brain cancer
A factor in how malignant tumors spread may also be a key to treatment.

Contact: Salk Communications
Salk Institute

Public Release: 8-Jan-2016
Racial disparity lies at intersection of HIV, Hodgkin lymphoma
Among HIV-positive patients with Hodgkin lymphoma, a new study finds that blacks are significantly less likely than whites to receive treatment for the cancer, even though chemotherapy saves lives.
American Society of Hematology

Contact: David Orenstein
Brown University

Public Release: 7-Jan-2016
JAMA Oncology
Higher cancer death rate associated with solid-organ transplant recipients
In solid-organ transplant recipients, the cancer death rate was higher than in the general population in a new study from Ontario, Canada, published online by JAMA Oncology.

Contact: Nancy N. Baxter
The JAMA Network Journals

Public Release: 7-Jan-2016
Cell Reports
New role of protein kinases in embryo development and cancer
A group of protein kinases have been found to play an important role in embryo development and may even be a potential cancer drug target, says research led by Queen Mary University of London and the Francis Crick Institute, UK.
Cancer Research UK, Barts Cancer Institute, HEFCE, Wellcome Trust, Royal Society

Contact: Joel Winston
Queen Mary University of London

Public Release: 7-Jan-2016
American Journal of Medicine
Smokers diagnosed with pneumonia found to have higher risk of lung cancer
A new study from Tel Aviv University proposes that screening heavy smokers admitted to the hospital with community-acquired pneumonia could facilitate the early diagnosis of lung cancer and thereby reduce the incidence of mortality.

Contact: George Hunka
American Friends of Tel Aviv University

Public Release: 7-Jan-2016
CA: A Cancer Journal for Clinicians
Cancer death rate continues steady drop
Steady reductions in smoking combined with advances in cancer prevention, early detection, and treatment have resulted in a 23 percent drop in the cancer death rate since its peak in 1991.

Contact: David Sampson
American Cancer Society

Public Release: 7-Jan-2016
Clinical Cancer Research
Blocking melanoma's escape: Avatars break theraping resistance in relapsed cancers
By utilizing a revolutionary method that allows mice to serve as 'avatars' for patients, scientists at The Wistar Institute have shown that a previously ineffective targeted drug for melanoma may actually be quite potent in halting the progression of disease in certain patients.
Novartis, Dr. Miriam and Sheldon G. Adelson Medical Research Foundation

Contact: Ben Leach
The Wistar Institute

Public Release: 7-Jan-2016
Molecular Cell
Scientist identifies energy sensor as potential target for cancer drugs
An international research team formed by a University of Cincinnati cancer researcher has shown for the first time that a specific enzyme is responsible for sensing the available supply of GTP, an energy source that fuels the uncontrolled growth of cancer cells. The research underscores the enzyme's potential to become a therapeutic target for future cancer drugs.

Contact: Cindy Starr
University of Cincinnati Academic Health Center

Public Release: 7-Jan-2016
Nature Chemistry
A 'printing press' for nanoparticles
Gold nanoparticles have unusual properties, which scientists are seeking to put to use in a range of technologies. Some of the most interesting properties emerge when nanoparticles are brought close together. But a major challenge has been finding ways to assemble these bits of gold while controlling the three-dimensional shape of their arrangement. In results reported in Nature Chemistry, researchers from McGill University outline a new technique.
Natural Sciences and Engineering Research Council of Canada, Canada Foundation for Innovation, Centre for Self-Assembled Chemical Structures, Canada Research Chairs Program, Canadian Institutes of Health Research

Contact: Chris Chipello
McGill University

Public Release: 7-Jan-2016
Proceedings of the National Academy of Sciences
Epigenetic regulation of metastatic breast cancer progression may guide prognosis and future therapy
A gene that plays a role in the development of breast cancer to metastatic disease has been identified which may help to predict disease progression and serve as a target for the development of future breast cancer therapies.
Susan G. Komen for the Cure, National Institutes of Health, BU Genome Science Institute, Research Promotion Foundation of Cyprus

Contact: Gina DiGravio
Boston University Medical Center

Showing releases 876-900 out of 1305.

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