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Public Release: 4-May-2016
Acta Obstetricia et Gynecologica Scandinavica
Medical conditions are more common in women who are sexually abused
Researchers have found that a variety of conditions are more common in women before and after sexual assault.

Contact: Penny Smith

Public Release: 3-May-2016
Chemoradiotherapy vs. chemotherapy for locally advanced pancreatic cancer
In a study appearing in the May 3 issue of JAMA, Pascal Hammel, M.D., of Beaujon Hospital, Clichy, France and colleagues assessed whether chemoradiotherapy improves overall survival of patients with locally advanced pancreatic cancer controlled after four months of gemcitabine-based induction chemotherapy, and assessed the effect of erlotinib on survival. Gemcitabine and erlotinib are drugs used to treat cancer.

Contact: Pascal Hammel, M.D.
The JAMA Network Journals

Public Release: 3-May-2016
EMBO Reports
Herbal remedies are an overlooked global health hazard
Scientists raise are raising awareness that long-term use of herbal remedies is no guarantee of their safety. Herbal remedies are an overlooked global hazard.

Contact: Dipali Pathak
Baylor College of Medicine

Public Release: 3-May-2016
Nature Genetics
Scientists double number of known genetic risk factors for endometrial cancer
An international collaboration of researchers has identified five new gene regions that increase a woman's risk of developing endometrial cancer, one of the most common cancers to affect women, taking the number of known gene regions associated with the disease to nine.
Cancer Research UK

Contact: Craig Brierley
University of Cambridge

Public Release: 3-May-2016
Trends in Genetics
Autism and cancer share a remarkable number of risk genes in common
Autism and cancer share more than 40 risk genes, suggesting that common mechanisms underlying the functions of some of these genes could conceivably be leveraged to develop therapies not just for cancer but for autism as well, an extensive assessment by researchers with the UC Davis MIND Institute and Comprehensive Cancer Center has found.

Contact: Phyllis K. Brown
University of California - Davis Health System

Public Release: 3-May-2016
Neurosurgical Focus
Barrow researchers prove utility of imaging tool in surgeon's hand
Barrow researchers prove the utility of new brain tumor imaging tool in the surgeon's hand.

Contact: Lynne Reaves
St. Joseph's Hospital and Medical Center

Public Release: 3-May-2016
Research points to a new treatment for pancreatic cancer
Researchers have shown how controlling cholesterol metabolism in pancreatic cancer cells reduces metastasis, pointing to a potential new treatment using drugs previously developed for atherosclerosis.
National Institutes of Health, NIH/National Cancer Institute

Contact: emil venere
Purdue University

Public Release: 2-May-2016
Five new breast cancer genes and range of mutations pave way for personalized treatment
The largest-ever study to sequence the whole genomes of breast cancers has uncovered five new genes associated with the disease and 13 new mutational signatures that influence tumor development. The results of two papers published in Nature and Nature Communications also reveal what genetic variations exist in breast cancers and where they occur in the genome.
European Union

Contact: Press Officer
Wellcome Trust Sanger Institute

Public Release: 2-May-2016
Proceedings of the National Academy of Sciences
Prevalent cancer-associated mutations detected in apparently healthy group
In a study of 36 women -- 16 diagnosed with ovarian cancer and a control group of 20 with no cancer diagnosis -- nearly all of the women were found to carry cancer-associated gene mutations. The study was an early test of DNA duplex sequencing, a technology developed at the University of Washington. Duplex sequencing independently tags molecules along both strands of DNA. In terms of a prospective diagnostic, its accuracy is thought to be unmatched.
Mary Kay Foundation, National Institutes of Health

Contact: Brian Donohue
University of Washington Health Sciences/UW Medicine

Public Release: 2-May-2016
Annals of Internal Medicine
ACP recommendations for treating chronic insomnia
The May 2 issue of Annals of Internal Medicine includes: 'ACP recommends cognitive behavioral therapy over drugs for treating chronic insomnia'; 'ICDs associated with high risk for long-term complications'; 'Scientific community seeks answers about explosive Zika outbreak'; 'Internists Recommend Ways to Better Align Graduate Medical Education Financing with Workforce Needs'; and more.

Contact: Cara Graeff
American College of Physicians

Public Release: 2-May-2016
Health Affairs
May Health Affairs: Value of cancer drugs in 9 countries
The May issue of Health Affairs includes a study examining real-world cancer drug consumption in nine countries. The authors, Sebastian Salas-Vega and Elias Mossialos, both with the London School of Economics and Political Science, compared the value in lives saved for cancer drug spending in Australia, Canada, France, Germany, Italy, Japan, Sweden, the United Kingdom and the United States, for the years 2004-14.

Contact: Sue Ducat
Health Affairs

Public Release: 2-May-2016
Journal of the National Cancer Institute
Elevated bladder cancer risk in New England and arsenic in drinking water
A new study has found that drinking water from private wells, particularly dug wells established during the first half of the 20th century, may have contributed to the elevated risk of bladder cancer that has been observed in Maine, New Hampshire, and Vermont for over 50 years.
NIH/National Cancer Institute

Contact: NCI press office
NIH/National Cancer Institute

Public Release: 2-May-2016
Nature Methods
Current cancer drug discovery method flawed: Study
The primary method used to test compounds for anti-cancer activity in cells is flawed, Vanderbilt University researchers report May 2 in Nature Methods. The findings cast doubt on methods used by the entire scientific enterprise and pharmaceutical industry to discover new cancer drugs. The researchers have developed a new metric to evaluate a compound's effect on cell proliferation -- called the DIP (drug-induced proliferation) rate -- that overcomes the flawed bias in the traditional method.
Uniting Against Lung Cancer, National Library of Medicine, NIH/National Cancer Institute, NIH/National Center for Advancing Translational Sciences

Contact: Leigh MacMillan
Vanderbilt University Medical Center

Public Release: 2-May-2016
Nature Cell Biology
Hormel Institute's Hinchcliffe leads groundbreaking cancer research study
A recent research study at The Hormel Institute, University of Minnesota is providing insight into the regulation of chromosome segregation and the mechanisms used by cells to prevent them from forming tumors.
'Paint the Town Pink'' initiative, US Department of Defensem, National Institutes of Health

Contact: Mandie Siems
University of Minnesota

Public Release: 2-May-2016
UTSW identifies new function of genes linked to Fanconi anemia and certain types of cancer
Researchers from UT Southwestern Medical Center have identified an important new function of genes in the Fanconi anemia pathway -- a finding that could have implications for development of new therapies to treat this disorder and some cancers.

Contact: Debbie Bolles
UT Southwestern Medical Center

Public Release: 2-May-2016
Cancer Research
Two known chemotherapy agents effectively target breast cancer stem cells
Two existing chemotherapy drugs appear to be a powerful pair in targeting errant stem cells that are making breast cancer and enabling its spread and recurrence, scientists report.
National Cancer Institute, Department of Defense

Contact: Toni Baker
Medical College of Georgia at Augusta University

Public Release: 2-May-2016
Cognitive-behavioral therapy may help reduce memory problems in cancer survivors who have received chemotherapy
A new analysis indicates that a type of psychotherapy delivered by videoconference may help prevent some of the long-term memory issues caused by chemotherapy

Contact: Dawn Peters

Public Release: 1-May-2016
Clinical Oncology
Radiotherapy more effective than chemotherapy for early stage II testicular cancer
A large study of testicular cancer patients has shown that radiation therapy is a better treatment than chemotherapy for patients with stage IIa disease (where one or more regional lymph nodes contain cancer cells but they are less than 2 cm in diameter). These findings, presented at the ESTRO 35 conference and published simultaneously in Clinical Oncology, are important because, until now, there has been little evidence about which treatment for testicular seminoma is more effective.

Contact: Emma Mason
European Society for Radiotherapy and Oncology (ESTRO)

Public Release: 1-May-2016
Bulletin of the World Health Organization
Growing threat of noncommunicable diseases to survival in pregnancy and childbirth
Fewer women in low and middle-income countries die due to conditions related to pregnancy and childbirth than 10 years ago. The study from Mexico highlights the risk that noncommunicable diseases could undermine recent progress in improving maternal survival.

Contact: Fiona Fleck
Bulletin of the World Health Organization

Public Release: 1-May-2016
Radiotherapy for lung cancer patients is linked to increased risk of non-cancer deaths
Researchers have found that treating patients who have early stage non-small cell lung cancer with a type of radiotherapy called stereotactic body radiation therapy is associated with a small but increased risk of death from causes other than cancer. The findings are presented at the annual meeting of the European Society for Radiotherapy and Oncology - ESTRO35.
Elekta Oncology Systems Ltd, Dutch Cancer Society

Contact: Emma Mason
European Society for Radiotherapy and Oncology (ESTRO)

Public Release: 1-May-2016
Cancer Research
New cancer drugs could treat lethal resistant prostate cancers
Men with aggressive prostate cancer that has stopped responding to conventional treatment could potentially benefit from a new class of cancer drug designed to overcome drug resistance, a new study suggests. Researchers found that the drugs, called Hsp90 inhibitors, specifically target and inactivate a mechanism commonly used by prostate cancer cells to evade the effects of standard treatment.
Wellcome Trust

Contact: Claire Hastings
Institute of Cancer Research

Public Release: 30-Apr-2016
Pediatric Academic Societies 2016 Meeting
Stress and depression is linked to HPV-related health problems
New research to be highlighted at the Pediatric Academic Societies 2016 Meeting is the first to suggest that stress and depression play a significant role in whether a woman with human papillomavirus (HPV) can get rid of her infection or not. HPV that lingers in a woman's system eventually can lead to cervical cancer.

Contact: Laura Milani Alessio
American Academy of Pediatrics

Public Release: 30-Apr-2016
Radiation and immunotherapy combination can destroy both primary and secondary tumors
Research to be presented to the ESTRO 35 conference today has shown that the addition of an immune system-strengthening compound to radiation therapy can extend the radiation therapy-induced immune response against the tumor sites and that this response even has an effect on tumors outside the radiation field.

Contact: Mary Rice
European Society for Radiotherapy and Oncology (ESTRO)

Public Release: 29-Apr-2016
Clay nanotube-biopolymer composite scaffolds for tissue engineering
Scientists of Bionanotechnology Lab, Kazan Federal University, combined three biopolymers, chitosan and agarose (polysaccharides), and a protein gelatine, as the materials to produce tissue engineering scaffolds and demonstrated the enhancement of mechanical strength (doubled pick load), higher water uptake and thermal properties in chitosan-gelatine-agarose hydrogels doped with halloysite.

Contact: Yevgeniya Litvinova
Kazan Federal University

Public Release: 29-Apr-2016
Plastic and Reconstructive Surgery
Good long-term quality of life after 'DIEP flap' breast reconstruction
For women who have undergone mastectomy for breast cancer, breast reconstruction using the abdominal 'DIEP flap' provides good long-term quality of life (QOL) -- similar to that of women without breast cancer, reports a study in the May issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).

Contact: Connie Hughes
Wolters Kluwer Health

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