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Public Release: 23-Apr-2014
Science Translational Medicine
Study shows aspirin can reduce colorectal cancer risks for those with specific gene
The humble aspirin may have just added another beneficial effect beyond its ability to ameliorate headaches and reduce the risk of heart attacks: lowering colon cancer risk among people with high levels of a specific type of gene.
NIH/National Cancer Institute, National Institutes of Health

Contact: Amanda Petrak
amanda.petrak@case.edu
216-317-7347
Case Western Reserve University

Public Release: 23-Apr-2014
Journal of Adolescent Health
RI Hospital physician: Legalizing medical marijuana doesn't increase use among adolescents
Parents and physicians concerned about an increase in adolescents' marijuana use following the legalization of medical marijuana can breathe a sigh of relief. According to a new study at Rhode Island Hospital, which compared 20 years worth of data from states with and without medical marijuana laws, legalizing the drug did not lead to increased use among adolescents. The study is published online in advance of print in the Journal of Adolescent Health.

Contact: Ellen Slingsby
eslingsby@lifespan.org
401-444-6421
Lifespan

Public Release: 23-Apr-2014
Annals of Oncology
Death rates from pancreatic cancer predicted to rise in Europe in 2014
Pancreatic cancer is the only cancer for which deaths are predicted to increase in men and women rather than decrease in 2014 and beyond, according to a comprehensive study published in the leading cancer journal Annals of Oncology. The study by researchers in Italy and Switzerland shows that the proportion of deaths due to any sort of cancer is expected to fall overall in Europe in 2014.

Contact: Emma Mason
wordmason@mac.com
European Society for Medical Oncology

Public Release: 23-Apr-2014
Nature
New target for prostate cancer resistant to anti-hormone therapies
Researchers have found a new target that could remain sensitive even when prostate cancer becomes resistant to current treatments.
Prostate Cancer Foundation, NIH/National Cancer Institute, Doris Duke Charitable Foundation, American Cancer Society

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 23-Apr-2014
Oncotarget
Non-uniform genetic mutations identified in lung cancers could lead to targeted treatment
Victorian researchers have extensively studied three of the more common genetic mutations and their distribution across individual lung cancers to see if they matched up to regions of different tumor architecture under the microscope.

Contact: Liz Banks-Anderson
banks@unimelb.edu.au
61-383-444-362
University of Melbourne

Public Release: 23-Apr-2014
Cancer Research
Scientists identify cancer specific cell for potential treatment of gastric cancer
A team of scientists led by a researcher from the Cancer Science Institute of Singapore at the National University of Singapore has identified the cancer specific stem cell which causes gastric cancer. This discovery opens up the possibility of developing new drugs for the treatment of this disease and other types of cancers.

Contact: Kimberley Wang
kimberley.wang@nus.edu.sg
National University of Singapore

Public Release: 22-Apr-2014
ACS Nano
Cloaked DNA nanodevices survive pilot mission
By mimicking a viral strategy, scientists at Harvard's Wyss Institute for Biologically Inspired Engineering have created the first cloaked DNA nanodevice that survives the body's immune defenses. Their success opens the door to smart DNA nanorobots that use logic to spot cancerous tissue and manufacture drugs on the spot to cripple it, as well as artificial microscopic containers called protocells that detect pathogens in food or toxic chemicals in drinking water.

Contact: Dan Ferber
dan.ferber@wyss.harvard.edu
617-432-1547
Wyss Institute for Biologically Inspired Engineering at Harvard

Public Release: 22-Apr-2014
JAMA Internal Medicine
False-positive mammogram anxiety has limited impact on women's well-being
Dartmouth researchers have found that the anxiety experienced with a false-positive mammogram is temporary and does not negatively impact a woman's overall well-being. Their findings are reported in 'Consequences of False-Positive Screening Mammograms,' which was published online in the April 21, 2014, JAMA Internal Medicine.
NIH/National Cancer Institute

Contact: Robin Dutcher
Robin.Dutcher@hitchcock.org
603-653-9056
The Geisel School of Medicine at Dartmouth

Public Release: 22-Apr-2014
American Journal of Physiology - Gastrointestinal and Liver Physiology
Two genes linked to inflammatory bowel disease
Cincinnati Cancer Center and University of Cincinnati Cancer Institute researcher Susan Waltz, Ph.D., and scientists in her lab have done what is believed to be the first direct genetic study to document the important function for the Ron receptor, a cell surface protein often found in certain cancers, and its genetic growth factor, responsible for stimulating cell growth, in the development and progression of inflammatory bowel disease.
Public Health Services, National Institutes of Health, US Veterans Administration, American Heart Association Great Rivers Affiliates

Contact: Katie Pence
katie.pence@uc.edu
513-558-4561
University of Cincinnati Academic Health Center

Public Release: 22-Apr-2014
Journal of Molecular Diagnostics
AMP publishes curriculum recommendations for medical laboratory scientists
The Association for Molecular Pathology released a report today in the Journal of Molecular Diagnostics on recommendations for a molecular diagnostics curriculum at both the baccalaureate and master's levels of education.

Contact: Catherine Davidge
cdavidge@amp.org
Association for Molecular Pathology

Public Release: 22-Apr-2014
Annals of Oncology
EORTC and SIOG update expert opinion on management of elderly patients with NSCLC
In an article appearing in the Annals of Oncology, the EORTC Cancer in the Elderly Task Force and Lung Cancer Group along with the International Society for Geriatric Oncology have updated their expert opinion on managing treatment for elderly patients with non-small cell lung cancer. This update includes recommendations for screening, surgery, adjuvant chemotherapy and radiotherapy, treatment of locally advanced and metastatic disease as well as new data on patient preferences and geriatric assessment.
Fonds Cancer

Contact: John Bean
john.bean@eortc.be
European Organisation for Research and Treatment of Cancer

Public Release: 22-Apr-2014
Cell Death & Disease
Scientists pinpoint protein that could improve small cell lung cancer therapies
Approximately 15 percent of all lung cancers are small cell lung cancers, which grow rapidly and often develop resistance to chemotherapy. However, researchers at Virginia Commonwealth University Massey Cancer Center have revealed new insights into the mechanisms leading to this resistance that may lead to improved therapies.
National Institutes of Health, NIH/National Cancer Institute

Contact: Alaina Schneider
afschneider@vcu.edu
804-628-4578
Virginia Commonwealth University

Public Release: 21-Apr-2014
Proceedings of the National Academy of Sciences
Scientists find key steps linking dietary fats and colon cancer tumor growth
Scientists have shown new genetic evidence that could strengthen the link between the role of dietary fats with colon cancer progression. The study, led by Arizona State University researcher and physician Dr. Raymond DuBois, M.D., Ph.D., has identified a molecular culprit, called peroxisome proliferator-activated receptor delta, that, when deleted in a mouse model of colon cancer, stopped key steps required for the initiation and progression of tumor growth.
National Institutes of Health

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-258-8972
Arizona State University

Public Release: 21-Apr-2014
Proceedings of the National Academy of Sciences
Fast, simple-to-use assay reveals the 'family tree' of cancer metastases
A Mass. General Hospital-based research team has developed a simple assay that can reveal the evolutionary relationships between primary tumors and metastases within a patient, information that may someday help with treatment planning.
US Department of Defense

Contact: Katie Marquedant
kmarquedant@partners.org
617-726-0337
Massachusetts General Hospital

Public Release: 21-Apr-2014
Proceedings of the National Academy of Sciences
'Dustman' protein helps bin cancer cells
Cancer researchers have discovered a new 'dustman' role for a molecule that helps a drug kill cancer cells according to a study, published in the journal Proceedings of the National Academy of Sciences.
Cancer Research UK

Contact: Paul Thorne
paul.thorne@cancer.org.uk
44-203-469-8352
Cancer Research UK

Public Release: 21-Apr-2014
JAMA Internal Medicine
False-positive mammograms associated with anxiety, willingness for future screening
Mammograms with false-positive results were associated with increased short-term anxiety for women, and more women with false-positive results reported that they were more likely to undergo future breast cancer screening.

Contact: Linda Kennedy
Linda.S.Kennedy@Dartmouth.edu
603-653-3612
The JAMA Network Journals

Public Release: 21-Apr-2014
Science Signaling
A gene within a gene contributes to the aggressiveness of acute myeloid leukemia
A small gene that is embedded in a larger gene plays a much greater role in promoting acute myeloid leukemia than the better-known host gene, according to a new study by Ohio State University cancer researchers. The research also identified a drug that inhibits expression of the smaller gene.
NIH/National Cancer Institute, Coleman Leukemia Research Foundation, Pelotonia Fellowship Program

Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Wexner Medical Center

Public Release: 21-Apr-2014
Stem Cell Reports
A protein required for integrity of induced pluripotent stem cells
A study published today in the journal Stem Cell Reports, from the Cell Publishing Group, reveals that the SIRT1 protein is needed to lengthen and maintain telomeres during cell reprogramming. SIRT1 also guarantees the integrity of the genome of stem cells that come out of the cell reprogramming process; these cells are known as induced pluripotent stem cells.

Contact: Nuria Noriega
comunicacion@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)

Public Release: 21-Apr-2014
Journal of Health Communication
IU study: Death of public figures provides important opportunities for health education
An Indiana University study of reactions to the 2011 death of Apple co-founder Steve Jobs suggests health communicators have a critical window of opportunity after a public figure dies to disseminate information about disease prevention and detection.

Contact: Jessica Gall Myrick
jgmyrick@indiana.edu
812-856-7380
Indiana University

Public Release: 21-Apr-2014
Proceedings of the National Academy of Sciences
Malfunction in molecular 'proofreader' prevents repair of UV-induced DNA damage
Malfunctions in the molecular 'proofreading' machinery, which repairs structural errors in DNA caused by ultraviolet light damage, help explain why people who have the disease xeroderma pigmentosum are at an extremely high risk for developing skin cancer, according to researchers at the University of Pittsburgh School of Medicine and the University of Pittsburgh Cancer Institute. Their findings will be published in the early online version of the Proceedings of the National Academy of Sciences.
University of Pittsburgh Cancer Institute, National Institutes of Health

Contact: Anita Srikameswaran
srikamav@upmc.edu
412-578-9193
University of Pittsburgh Schools of the Health Sciences

Public Release: 20-Apr-2014
Nature Cell Biology
Cancer stem cells linked to drug resistance
Most drugs used to treat lung, breast and pancreatic cancers also promote drug-resistance and ultimately spur tumor growth. Researchers at the University of California, San Diego School of Medicine have discovered a molecule, or biomarker, called CD61 on the surface of drug-resistant tumors that appears responsible for inducing tumor metastasis by enhancing the stem cell-like properties of cancer cells.
National Institutes of Health, NIH/National Cancer Institute

Contact: Yadira Galindo
ygalindo@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 20-Apr-2014
Nature Genetics
Dana-Farber researchers uncover link between Down syndrome and leukemia
A team of researchers led by Dana-Farber Cancer Institute investigators has uncovered a connection between people with Down syndrome and having a heightened risk of developing acute lymphoblastic leukemia during childhood.
Conquer Cancer Foundation, Lauri Strauss Leukemia Foundation, Leukemia and Lymphoma Society

Contact: Teresa Herbert
teresamarieherbert@gmail.com
617-632-4090
Dana-Farber Cancer Institute

Public Release: 20-Apr-2014
Nature Biotechnology
Computational method dramatically speeds up estimates of gene expression
With gene expression analysis growing in importance for both basic researchers and medical practitioners, researchers at Carnegie Mellon University and the University of Maryland have developed a new computational method that dramatically speeds up estimates of gene activity from RNA sequencing data.
National Science Foundation, National Institutes of Health

Contact: Byron Spice
bspice@cs.cmu.edu
412-268-9068
Carnegie Mellon University

Public Release: 18-Apr-2014
Cancer Epidemiology, Biomarkers & Prevention
Chronic inflammation may be linked to aggressive prostate cancer
The presence of chronic inflammation in benign prostate tissue was associated with high-grade, or aggressive, prostate cancer, and this association was found even in those with low prostate-specific antigen levels, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
NIH/National Cancer Institute

Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research

Public Release: 18-Apr-2014
Cancer Epidemiology, Biomarkers & Prevention
Chronic inflammation linked to 'high-grade' prostate cancer
Men who show signs of chronic inflammation in non-cancerous prostate tissue may have nearly twice the risk of actually having prostate cancer than those with no inflammation, according to results of a new study led by researchers from the Johns Hopkins Kimmel Cancer Center.
NIH/National Cancer Institute

Contact: Michelle Potter
mpotter8@jhmi.edu
410-614-2914
Johns Hopkins Medicine

Showing releases 876-900 out of 1234.

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