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Showing releases 876-900 out of 1195. << < 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 > >>
Public Release: 17-Jan-2013
 Cancer ResearchNew model may help predict response to chemotherapy for colorectal cancer Scientists may be able to better predict which patients with colorectal cancer will respond to chemotherapy using a new mathematical model that measures the amount of stress required for a cancer cell to die without harming healthy tissue. Contact: Jeremy Moore
Public Release: 17-Jan-2013
CA: A Cancer Journal for CliniciansCancer mortality down 20 percent from 1991 peak An annual report from the American Cancer Society finds as of 2009, the overall death rate for cancer in the United States had declined 20 percent from its peak in 1991, translating to the avoidance of approximately 1.2 million deaths from cancer, 152,900 of these in 2009 alone. 
American Cancer Society
Contact: David Sampson
Public Release: 16-Jan-2013
PLOS ONEUAlberta medical researchers find DNA marker that predicts breast cancer recurrence Medical researchers at the University of Alberta tested the DNA of more than 300 women in Alberta and discovered a 'genetic marker' method to help accurately profile which women were more apt to have their breast cancer return years later.
Canadian Breast Cancer Foundation -- Prairies/NWT region, Alberta Cancer Foundation
Contact: Raquel Maurier
Public Release: 16-Jan-2013
JAMA SurgeryStudy suggests lung cancer mortality highest in black persons living in most segregated counties Lung cancer mortality appears to be higher in black persons and highest in blacks living in the most segregated counties in the United States, regardless of socioeconomic status. Contact: Clare LaFond
Public Release: 16-Jan-2013
Journal of Clinical InvestigationHepatitis B virus promotes oncogenesis through microRNA modulation In this issue of the Journal of Clinical Investigation, Xiaoje Xu and colleagues at the Beijing Institute of Biotechnology report that miR-148a is repressed by hepatitis B virus (HBV) X protein (HBx) to promote growth and metastasis of liver cancer.
Major State Basic Research Development Program, National Natural Science Foundation
Contact: Jillian Hurst
Public Release: 16-Jan-2013
JAMA DermatologyInaccurate diagnoses of melanoma by smartphone apps could delay doctor visits, life-saving treatment Smartphone applications that claim to evaluate a user's photographs of skin lesions for the likelihood of cancer instead returned highly variable and often inaccurate feedback, according to a study led by researchers at the University of Pittsburgh School of Medicine. The findings, published in JAMA Dermatology and available online today, suggest that relying on these "apps" instead of consulting with a physician may delay the diagnosis of melanoma and timely, life-saving treatment.
National Institutes of Health, University of Pittsburgh Clinical and Translational Science Institute
Contact: Carrie Stevenson
Public Release: 16-Jan-2013
Journal of Clinical InvestigationBody's ibuprofen, SPARC, reduces inflammation and thus bladder cancer development and metastasis A University of Colorado Cancer Center study published today in the Journal of Clinical Investigation shows that the protein SPARC (Secreted Protein Acidic and Rich in Cysteine) acts much like an anti-inflammatory drug, attempting to heal tissues inflamed by tumors.
NIH/National Cancer Institute
Contact: Garth Sundem
Public Release: 16-Jan-2013
Journal of Clinical InvestigationJCI early table of contents for Jan. 16, 2013 This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, Jan. 16, 2013, in the JCI: Could probiotics help HIV patients?; Hepatitis B virus promotes oncogenesis through microRNA modulation; Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation; Dynamic visualization of RANKL and Th17-mediated osteoclast function; and many more. Contact: Jillian Hurst
Public Release: 16-Jan-2013
Nature GeneticsGene in eye melanomas linked to good prognosis Melanomas that develop in the eye often are fatal. Now, scientists at Washington University School of Medicine in St. Louis report they have identified a mutated gene in melanoma tumors of the eye that appears to predict a good outcome.
National Institutes of Health, Melanoma Research Alliance, Melanoma Research Foundation
Contact: Caroline Arbanas
Public Release: 16-Jan-2013
Cancer LettersAs colorectal cancer gets more aggressive, treatment with grape seed extract is even more effective "This study shows that many of the same mutations that allow colorectal cancer cells to metastasize and survive traditional therapies make them especially sensitive to treatment with GSE," says Molly Derry, doctoral candidate in the lab of Rajesh Agarwal, Ph.D., investigator at the CU Cancer Center and professor at the Skaggs School of Pharmacy and Pharmaceutical Sciences.
NIH/National Cancer Institute
Contact: Garth Sundem
Public Release: 16-Jan-2013
Public HealthBreast cancer mortality has not declined in women over 85 Since 1992 the number of deaths linked to breast cancer in Spain has decreased among young and middle aged patients, but not among the elderly. Spanish researchers also predict that it will continue to decline over the next decade, although more slowly. Contact: Press Office
Public Release: 16-Jan-2013
European Journal of Human GeneticsDeveloped new method to diagnose hereditary breast and ovarian cancer Researchers of the Catalan Institute of Oncology at the Bellvitge Biomedical Research Institute have developed and validated a new method to diagnose hereditary breast and ovarian cancer syndrome based on mass sequencing of BRCA1 and BRCA2 genes. The model is based on a genetic and bioinformatic analysis which has been proved very effective. The new protocol has been described in an article published in the European Journal of Human Genetics. Contact: Raül Toran
Public Release: 16-Jan-2013
Journal of Medicinal ChemistryDevelopment of the first way to make large amounts of promising anti-cancer substance Scientists are reporting development of the first practical way to make large amounts of a promising new anti-cancer substance that kills cancer cells differently than existing medicines. Their article on synthesis of the substance, and tests demonstrating its effectiveness in the laboratory, appears in ACS' Journal of Medicinal Chemistry. Contact: Michael Bernstein
Public Release: 16-Jan-2013
Pharmacoepidemiology and Drug SafetyBreast Cancer Message Board study finds frequent discussion of drug side effects, stopping therapy In the first study to examine discussion of drug side effects on Internet message boards, researchers from the Perelman School of Medicine at the University of Pennsylvania found that breast cancer survivors taking the commonly prescribed adjuvant therapy known as aromatase inhibitors often detailed in these forums troublesome symptoms resulting from the drugs, and they were apt to report discontinuing the treatment or switching to a different drug in the same class.
National Institutes of Health, NIH/National Library of Medicine, American Cancer Society
Contact: Holly Auer
Public Release: 15-Jan-2013
Nature GeneticsResearchers identify genetic mutation for rare cancer By looking at the entire DNA from this one patient's tumor, researchers have found a genetic anomaly that provides an important clue to improving how a rare type of cancer is diagnosed and treated.
NIH/National Cancer Institute
Contact: Nicole Fawcett
Public Release: 15-Jan-2013
British Journal of Urology InternationalKaiser Permanente study: Change in PSA levels over time can help predict aggressive prostate cancer Measurements taken over time of prostate specific antigen, the most commonly used screening test for prostate cancer in men, improve the accuracy of aggressive prostate cancer detection when compared to a single measurement of PSA, according to a Kaiser Permanente study published today in the British Journal of Urology International.
Beckman Coulter
Contact: Jacqueline Brown
Public Release: 15-Jan-2013
Journal of Thoracic OncologyEGFR mutation not prognostic factor in non-small cell lung cancer A recent study published in the February 2013 issue of the International Association for the Study of Lung Cancer's Journal of Thoracic Oncology, concludes EGFR mutations are not a prognostic factor in surgically resected patients or patients with recurrence treated with conventional therapies. However, after disease recurrence, administration of EGFR tyrosine kinase inhibitors can prolong survival. Contact: Kristal Griffith
Public Release: 15-Jan-2013
Journal of Thoracic OncologyPatients with EGFR exon 20 insertions have poorer prognosis A recent study published in the February 2013 issue of the International Association for the Study of Lung Cancer's Journal of Thoracic Oncology, concludes that patients with EGFR exon 20 insertions have similar clinical characteristics to those with common EGFR mutations, but a poorer prognosis. Contact: Kristal Griffith
Public Release: 15-Jan-2013
Journal of Thoracic OncologyComparable patterns of failure between SBRT, lobectomy or pneumonectomy for stage I NSCLC For patients with medically operable clinical stage I non–small-cell lung cancer (NSCLC), lobectomy or pneumonectomy is the standard approach. For patients with medically inoperable stage I NSCLC, stereotactic body radiotherapy has become a standard of care. Researchers from the Washington University School of Medicine wanted to compare the patterns of failure between each method. Contact: Kristal Griffith
Public Release: 14-Jan-2013
PLOS ONECervical cancer screening in less-developed areas should be tailored to local conditions The best approach to detecting cervical cancer in HIV-positive women living in research limited countries such as those in Sub-Saharan Africa combines commonly used testing methods tailored to local levels of development and medical infrastructure, according to a study by researchers from and the University of Witwatersrand in South Africa and the University of North Carolina. Contact: William Davis
Public Release: 14-Jan-2013
EMBO Molecular MedicineLiver controls wasting in cancer Many cancer patients suffer from a dramatic loss of fat and muscle mass. This extreme wasting, or cachexia, is often the actual cause of death in cancer patients. Heidelberg scientists have now discovered in mice that tumors stimulate the production of a key gene switch in the liver. Activity of this switch lowers blood fat levels so that the animals lose weight. This finding may lead to approaches to slow down this fatal loss of body mass. Contact: Dr. Sibylle Kohlstädt
Public Release: 14-Jan-2013
Gynecologic OncologyResearch makes connetion between tubal ligation and increase in cervical cancer rates Women who have a tubal ligation -- the surgical tying or severing of fallopian tubes to prohibit pregnancy -- have less frequent Pap smears, which puts them at an increased risk for cervical cancer, according to research recently released by a team that included Cara A. Mathews, M.D., a gynecologic oncologist at the Program in Women's Oncology at Women & Infants Hospital of Rhode Island. Contact: Susan McDonald
Public Release: 14-Jan-2013
OncogeneFox Chase researchers discover novel role of the NEDD9 gene in early stages of breast cancer Breast cancer is the second leading cause of cancer deaths among women in the United States. Many of these deaths occur when there is an initial diagnosis of invasive or metastatic disease. A protein called NEDD9 has been linked to tumor invasion and metastasis in a variety of cancers. Researchers at Fox Chase have now shown that NEDD9 plays a surprising role in the early stages of breast tumor development by controlling the growth of progenitor cells that give rise to tumors. Contact: Diana Quattrone
Public Release: 14-Jan-2013
Cancer DiscoveryScientists find a new way to boost common cancer drugs Shutting down a specific pathway in cancer cells appears to improve the ability of common drugs to wipe those cells out, according to new research from scientists at Fox Chase Cancer Center, published in the January issue of Cancer Discovery. Contact: Diana Quattrone
Public Release: 14-Jan-2013
Cancer CellTeam finds gene that promotes drug resistance in cancer Scientists from the UI and BYU have identified a gene that may be a target for overcoming drug resistance in cancer. The finding could improve prognostic and diagnostic tools for evaluating cancer and monitoring patient response to treatment. It also could lead to new therapies for eradicating drug-resistant cancer cells.
NIH/National Cancer Institute, Leukemia and Lymphoma Society, Multiple Myeloma Research Foundation
Contact: Jennifer Brown
Showing releases 876-900 out of 1195. << < 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 > >>
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