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Showing releases 876-900 out of 1336.

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Public Release: 3-Feb-2016
Promising compounds against a cancer target
Advances in new treatments for diseases, including cancer, come about from innovative research with therapeutic potential. This was the starting point for the Peptides and Proteins Lab at the Institute for Research in Biomedicine (IRB Barcelona) three years ago when it began to design compounds that block the binding of Epidermal Growth Factor (EGF) to its receptor (EGFR). The interaction between these two proteins accelerates the metabolism of tumor cells, thus favoring their growth and division.

Contact: Sònia Armengou
Institute for Research in Biomedicine (IRB Barcelona)

Public Release: 3-Feb-2016
Future Oncology
Consensus statement from the International Radiosurgery Oncology Consortium for Kidney
Future Science Group today announced the publication of a new article in Future Oncology, presenting a consensus statement from the International Radiosurgery Oncology Consortium for Kidney for primary renal cell carcinoma.

Contact: Leela Ripton
Future Science Group

Public Release: 3-Feb-2016
Hepatitis virus-like particles as potential cancer treatment
UC Davis researchers have developed a way to use the empty shell of a hepatitis E virus to carry vaccines or drugs into the body. The technique has been tested in rodents as a way to target breast cancer, and is available for commercial licensing through UC Davis Office of Research.
National Institutes of Health, Academia Sinica

Contact: Andy Fell
University of California - Davis

Public Release: 3-Feb-2016
American Journal of Clinical Oncology
No proof that radiation from X rays and CT scans causes cancer
The widespread belief that radiation from X rays, CT scans and other medical imaging can cause cancer is based on an unproven, decades-old theoretical model, according to a study published in the American Journal of Clinical Oncology.

Contact: Jim Ritter
Loyola University Health System

Public Release: 3-Feb-2016
Genes & Development
Enzyme key to link between age-related inflammation and cancer
For the first time, researchers have shown that an enzyme key to regulating gene expression -- and also an oncogene when mutated -- is critical for the expression of numerous inflammatory compounds that have been implicated in age-related increases in cancer and tissue degeneration, according to new research from Penn. Inhibitors of the enzyme are being developed as a new anti-cancer target.
NIH/National Institute of Aging, Dermatology Foundation, American Skin Association, and Melanoma Research Foundation

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 3-Feb-2016
Nature Communications
CNIO scientists find new tumor markers for the prognosis of head and neck cancer
Researchers have found that these tumors can be classified into two types using the p21 and mTOR markers . The presence of these markers corresponds to a less aggressive evolution of the disease. This could be the basis for more specific treatments depending on the type of cancer. Head and neck cancers are listed sixth in incidence and constitute the eighth leading cause of death by cancer.

Contact: Vanessa Pombo
Centro Nacional de Investigaciones Oncológicas (CNIO)

Public Release: 3-Feb-2016
Cancer Research
Nutrient deprivation kills kidney cancer cells
Duke researchers have exploited the greedy metabolism of cancer cells to target kidney cell carcinomas, which kill more than 100,000 Americans each year. The team showed that the majority of renal cell cancers rewire their metabolism in a way that leaves them addicted to the nutrient cystine. By depriving the cancer cells of cystine, the researchers were able to trigger a form of cell death called necrosis in tumor cells.
National Institutes of Health, Department of Defense, Duke Cancer Center Pilot Project fund

Contact: Karl Bates
Duke University

Public Release: 3-Feb-2016
Cochrane Library
Cochrane news: Have national smoking bans worked in reducing harms in passive smoking?
The most robust evidence yet, published today in the Cochrane Library, suggests that national smoking legislation does reduce the harms of passive smoking, and particularly risks from heart disease.

Contact: Dawn Peters

Public Release: 3-Feb-2016
New England Journal of Medicine
Preventive surgery for women at high risk of breast and ovarian cancer
In a review article published in the Feb. 4 issue of the New England Journal of Medicine, a pair of Mayo Clinic Cancer Center researchers provide an in-depth look at the issues associated with the care of women in families with hereditary breast and ovarian cancer syndrome who have not yet developed cancer themselves.

Contact: Joe Dangor
Mayo Clinic

Public Release: 2-Feb-2016
Nature Communications
'Junk' DNA plays role in preventing breast cancer
Supposed "junk" DNA, found in between genes, plays a role in suppressing cancer, according to new research by Universities of Bath and Cambridge.
Cancer Research UK, Cancer Research at Bath, The University of Cambridge, Hutchison Whampoa Limited

Contact: Vicky Just
University of Bath

Public Release: 2-Feb-2016
Scientists create imaging 'toolkit' to help identify new brain tumor drug targets
Stopping the growth of blood vessels in tumors is a key target for glioblastoma therapies, and imaging methods are essential for initial diagnosis and monitoring the effects of treatments. A team of researchers have developed a combined magnetic resonance imaging (MRI) and ultramicroscopy 'toolkit' to study vessel growth in glioma models in more detail than previously possible. Their study is to be published in the journal eLife.
CHS Stiftung/CHS Foundation, Medical Faculty of the University of Heidelberg

Contact: Emily Packer

Public Release: 2-Feb-2016
Rate of office visits, cumulative costs prior to colonoscopies for colon cancer screening
Kevin R. Riggs, M.D., M.P.H., of the Johns Hopkins University School of Medicine, Baltimore, and colleagues analyzed billing data to determine the proportion of colonoscopies for colon cancer screening and polyp surveillance that were preceded by office visits and the associated payments for those visits. The study appears in the Feb. 2 issue of JAMA.

Contact: Marin Hedin
The JAMA Network Journals

Public Release: 2-Feb-2016
Lancet Diabetes & Endocrinology
Height influences risk of cardiovascular disease, diabetes, and cancer
Scientists at the German Center for Diabetes Research (DZD) and the Harvard School of Public Health describe the relationship of the worldwide increase in height with the development of leading chronic non-communicable diseases in the journal The Lancet Diabetes & Endocrinology. Tall people have a lower risk for cardiovascular disease and type 2 diabetes, but a higher risk of cancer. The authors discuss which dietary factors and other mechanisms may explain these associations.

Contact: Dr. Astrid Glaser
Deutsches Zentrum fuer Diabetesforschung DZD

Public Release: 2-Feb-2016
British Journal of Cancer
Backing from their GP could lead thousands more to take bowel cancer test
Almost 40,000 more people might take a bowel cancer test in England each year if the letter inviting them to do so was endorsed by their GP.

Contact: Fiona
Cancer Research UK

Public Release: 2-Feb-2016
Nature Immunology
Sharpin emerges from the pack as a regulator of inflammation
it is normal -- in fact necessary -- for our immune system to occasionally fly into an inflammatory rage to defend the host (us) against pathogens or even tumor cells. Problems arise when the rage persists or is re-directed against one's self, as occurs in autoimmune disease.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Jessica Roi
La Jolla Institute for Allergy and Immunology

Public Release: 2-Feb-2016
Proceedings of the National Academy of Sciences
Minority of cancer cells affect the growth and metastasis of tumors
New research shows that a small minority of cancer cells in neuroendocrine tumors of the pancreas contribute to the overall growth and metastasis of the tumor. This discovery was made by a research group at Lund University, in collaboration with researchers at Karolinska Institutet, in Sweden.
Göran and Birgitta Grosskopf, European Research Council, Swedish Cancer Society, Swedish Research Council, and BioCARE

Contact: Cecilia Schubert
Lund University

Public Release: 2-Feb-2016
Nature Genetics
'Gene fusion' mutation uses 3-way mechanism to drive childhood brain cancers
A powerful, three-way mechanism by which a mutation drives the growth of childhood brain cancers, was discovered by scientists. The team hopes the discovery will lead to better methods for diagnosing and treating these cancers, which cannot always be cured with surgery.
National Institutes of Health, A Kids' Brain Tumor Cure Foundation/Pediatric Low-Grade Astrocytoma Foundation, Voices Against Brain Cancer, Thea's Star of Hope, and Why Not Me Inc.

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 2-Feb-2016
European Journal of Cardio-Thoracic Surgery
Study suggests improvements in how mesothelioma is staged
A new study suggests that significant improvements could be made in the scoring system physicians use to estimate the stage (severity) of mesothelioma, an aggressive and deadly cancer.

Contact: Jim Ritter
Loyola University Health System

Public Release: 2-Feb-2016
Novel nanoparticle made of common mineral may help keep tumor growth at bay
Engineers at Washington University in St. Louis found a way to keep a cancerous tumor from growing by using nanoparticles of the main ingredient in common antacid tablets.
National Institutes of Health

Contact: Erika Ebsworth-Goold
Washington University in St. Louis

Public Release: 2-Feb-2016
Autophagy -- a review of techniques
The third edition of 'Guidelines for the use and interpretation of assays for monitoring autophagy' was recently published in the leading journal Autophagy, featuring TGAC's Autophagy Regulatory Network resource and co-authored by Dr. Tamas Korcsmaros, Computational Biology Fellow at The Genome Analysis Centre and Institute of Food Research.

Contact: Hayley London
The Genome Analysis Centre

Public Release: 1-Feb-2016
Cell Reports
Researchers identify potential targeted therapy for lung cancer using fly model
A drug approved by the Food and Drug Administration for melanoma in combination with a common cholesterol-lowering drug may show promise in controlling cancer growth in patients with non-small cell lung cancer, according to new research from the Icahn School of Medicine at Mount Sinai.
National Institutes of Health

Contact: Lucia Lee
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 1-Feb-2016
Journal of Women's Health
Preventing cardiovascular disease in women -- one physician's approach to juggling the many guidelines
Nanette K. Wenger, M.D., Professor of Medicine (Cardiology) Emeritus, Emory University School of Medicine, provides a comprehensive perspective on how to apply the many new and continuously updated guidelines for preventing cardiovascular disease (CVD) and reducing CVD risk factors in women, in a clear and concise review article published in Journal of Women's Health.

Contact: Kathryn Ryan
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 1-Feb-2016
Computers, Informatics, Nursing
When loved ones battle cancer, families head to Web for information more than support
Loved ones of cancer patients are likely to search for further information about the disease online but less inclined to seek emotional support from social media forums, according to a University of Georgia study. It is fairly common for loved ones of cancer patients to develop depression or anxiety disorders, but there aren't many studies focusing specifically on cancer patients' caregivers and family members, said the study's author, Carolyn Lauckner.
Michigan State University's College of Communication Arts and Sciences

Contact: Stephanie Schupska
University of Georgia

Public Release: 1-Feb-2016
Cancer Research
Turning down the volume on cancer
When the audio on your television set is too loud, you simply turn down the volume. What if we could do the same for signaling in our bodies that essentially causes normal cells to turn cancerous? New discoveries by researchers at the Stephenson Cancer Center at the University of Oklahoma may point to ways to do just that. Hiroshi Y. Yamada, Ph.D., and his team identified previously unknown targets for colon cancer prevention and treatment.
NIH/National Cancer Institute, Chris4Life Colon Cancer Foundation, NIH/National Center for Research Resources, NIH/National Institute of General Medical Sciences

Contact: Theresa Green
University of Oklahoma

Public Release: 1-Feb-2016
Proceedings of the National Academy of Sciences
A 'gap in the armor' of DNA may allow enzyme to trigger cancer-causing mutations
Research from Indiana University published in the Proceedings of the National Academy of Sciences has identified a genetic mechanism that is likely to drive mutations that can lead to cancer.
US Army Research Office, National Institutes of Health

Contact: Kevin D. Fryling
Indiana University

Showing releases 876-900 out of 1336.

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