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Showing releases 901-925 out of 1206. << < 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 > >>
Public Release: 16-Jan-2013
 PLOS ONEUAlberta medical researchers find DNA marker that predicts breast cancer recurrence Medical researchers at the University of Alberta tested the DNA of more than 300 women in Alberta and discovered a 'genetic marker' method to help accurately profile which women were more apt to have their breast cancer return years later. 
Canadian Breast Cancer Foundation -- Prairies/NWT region, Alberta Cancer Foundation
Contact: Raquel Maurier
Public Release: 16-Jan-2013
Journal of Clinical InvestigationBody's ibuprofen, SPARC, reduces inflammation and thus bladder cancer development and metastasis A University of Colorado Cancer Center study published today in the Journal of Clinical Investigation shows that the protein SPARC (Secreted Protein Acidic and Rich in Cysteine) acts much like an anti-inflammatory drug, attempting to heal tissues inflamed by tumors.
NIH/National Cancer Institute
Contact: Garth Sundem
Public Release: 16-Jan-2013
Journal of Clinical InvestigationJCI early table of contents for Jan. 16, 2013 This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, Jan. 16, 2013, in the JCI: Could probiotics help HIV patients?; Hepatitis B virus promotes oncogenesis through microRNA modulation; Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation; Dynamic visualization of RANKL and Th17-mediated osteoclast function; and many more. Contact: Jillian Hurst
Public Release: 16-Jan-2013
JAMA SurgeryStudy suggests lung cancer mortality highest in black persons living in most segregated counties Lung cancer mortality appears to be higher in black persons and highest in blacks living in the most segregated counties in the United States, regardless of socioeconomic status. Contact: Clare LaFond
Public Release: 16-Jan-2013
Journal of Clinical InvestigationHepatitis B virus promotes oncogenesis through microRNA modulation In this issue of the Journal of Clinical Investigation, Xiaoje Xu and colleagues at the Beijing Institute of Biotechnology report that miR-148a is repressed by hepatitis B virus (HBV) X protein (HBx) to promote growth and metastasis of liver cancer.
Major State Basic Research Development Program, National Natural Science Foundation
Contact: Jillian Hurst
Public Release: 15-Jan-2013
British Journal of Urology InternationalKaiser Permanente study: Change in PSA levels over time can help predict aggressive prostate cancer Measurements taken over time of prostate specific antigen, the most commonly used screening test for prostate cancer in men, improve the accuracy of aggressive prostate cancer detection when compared to a single measurement of PSA, according to a Kaiser Permanente study published today in the British Journal of Urology International.
Beckman Coulter
Contact: Jacqueline Brown
Public Release: 15-Jan-2013
Nature GeneticsResearchers identify genetic mutation for rare cancer By looking at the entire DNA from this one patient's tumor, researchers have found a genetic anomaly that provides an important clue to improving how a rare type of cancer is diagnosed and treated.
NIH/National Cancer Institute
Contact: Nicole Fawcett
Public Release: 15-Jan-2013
Journal of Thoracic OncologyEGFR mutation not prognostic factor in non-small cell lung cancer A recent study published in the February 2013 issue of the International Association for the Study of Lung Cancer's Journal of Thoracic Oncology, concludes EGFR mutations are not a prognostic factor in surgically resected patients or patients with recurrence treated with conventional therapies. However, after disease recurrence, administration of EGFR tyrosine kinase inhibitors can prolong survival. Contact: Kristal Griffith
Public Release: 15-Jan-2013
Journal of Thoracic OncologyComparable patterns of failure between SBRT, lobectomy or pneumonectomy for stage I NSCLC For patients with medically operable clinical stage I non–small-cell lung cancer (NSCLC), lobectomy or pneumonectomy is the standard approach. For patients with medically inoperable stage I NSCLC, stereotactic body radiotherapy has become a standard of care. Researchers from the Washington University School of Medicine wanted to compare the patterns of failure between each method. Contact: Kristal Griffith
Public Release: 15-Jan-2013
Journal of Thoracic OncologyPatients with EGFR exon 20 insertions have poorer prognosis A recent study published in the February 2013 issue of the International Association for the Study of Lung Cancer's Journal of Thoracic Oncology, concludes that patients with EGFR exon 20 insertions have similar clinical characteristics to those with common EGFR mutations, but a poorer prognosis. Contact: Kristal Griffith
Public Release: 14-Jan-2013
OncogeneUnderstanding brain tumor growth opens door for non-surgical treatment Researchers from Plymouth University Peninsula Schools of Medicine and Dentistry have for the first time identified a new group of growth factor receptors for brain tumors. Understanding how these work could mean that existing drugs could be used as alternative therapy to surgery or radiotherapy for patients with multiple brain tumors. Contact: Andrew Gould
Public Release: 14-Jan-2013
Cancer CellResearchers reveal aggressive breast cancer's metastatic path Scientists at Weill Cornell Medical College have discovered the molecular switch that allows aggressive triple negative breast cancer cells to grow the amoeba-like protrusions they need to crawl away from a primary tumor and metastasize throughout the body. Their findings, published in Cancer Cell, suggest a novel approach for developing agents to treat cancer once it has spread.
Neuberger Berman Lung Cancer Laboratory, Robert I. Goldman Foundation
Contact: Lauren Woods
Public Release: 14-Jan-2013
CancerSmoking intensity and cancer markers predict seriousness of bladder cancer Smoking not only causes bladder cancer--it also affects its course, in that people who smoke more have greater likelihood of developing more aggressive and deadly disease. That is one of the conclusions of a new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society. The study also found that a panel of bladder cancer markers can predict which particular cases are at the highest risk for a fatal outcome. Contact: Amy Molnar
Public Release: 14-Jan-2013
Annals of Family MedicineJanuary/February 2013 Annals of Family Medicine tip sheet This advisory offers synopses of new research published in the January/February 2013 issue of Annals of Family Medicine research journal. Contact: Angela Sharma
Public Release: 14-Jan-2013
FEBS LettersResearch suggests molecular 'switch' may play role in tumor suppression Indiana University structural biologist Joel Ybe and colleagues identify a "topology switch" in the protein clathrin, the function of which may shed light on molecular processes involved in tumor suppression.
National Institutes of Health
Contact: Steve Hinnefeld
Public Release: 14-Jan-2013
Cancer CellTeam finds gene that promotes drug resistance in cancer Scientists from the UI and BYU have identified a gene that may be a target for overcoming drug resistance in cancer. The finding could improve prognostic and diagnostic tools for evaluating cancer and monitoring patient response to treatment. It also could lead to new therapies for eradicating drug-resistant cancer cells.
NIH/National Cancer Institute, Leukemia and Lymphoma Society, Multiple Myeloma Research Foundation
Contact: Jennifer Brown
Public Release: 14-Jan-2013
EMBO Molecular MedicineLiver controls wasting in cancer Many cancer patients suffer from a dramatic loss of fat and muscle mass. This extreme wasting, or cachexia, is often the actual cause of death in cancer patients. Heidelberg scientists have now discovered in mice that tumors stimulate the production of a key gene switch in the liver. Activity of this switch lowers blood fat levels so that the animals lose weight. This finding may lead to approaches to slow down this fatal loss of body mass. Contact: Dr. Sibylle Kohlstädt
Public Release: 14-Jan-2013
OncogeneFox Chase researchers discover novel role of the NEDD9 gene in early stages of breast cancer Breast cancer is the second leading cause of cancer deaths among women in the United States. Many of these deaths occur when there is an initial diagnosis of invasive or metastatic disease. A protein called NEDD9 has been linked to tumor invasion and metastasis in a variety of cancers. Researchers at Fox Chase have now shown that NEDD9 plays a surprising role in the early stages of breast tumor development by controlling the growth of progenitor cells that give rise to tumors. Contact: Diana Quattrone
Public Release: 14-Jan-2013
Cancer DiscoveryScientists find a new way to boost common cancer drugs Shutting down a specific pathway in cancer cells appears to improve the ability of common drugs to wipe those cells out, according to new research from scientists at Fox Chase Cancer Center, published in the January issue of Cancer Discovery. Contact: Diana Quattrone
Public Release: 14-Jan-2013
Gynecologic OncologyResearch makes connetion between tubal ligation and increase in cervical cancer rates Women who have a tubal ligation -- the surgical tying or severing of fallopian tubes to prohibit pregnancy -- have less frequent Pap smears, which puts them at an increased risk for cervical cancer, according to research recently released by a team that included Cara A. Mathews, M.D., a gynecologic oncologist at the Program in Women's Oncology at Women & Infants Hospital of Rhode Island. Contact: Susan McDonald
Public Release: 14-Jan-2013
PLOS ONECervical cancer screening in less-developed areas should be tailored to local conditions The best approach to detecting cervical cancer in HIV-positive women living in research limited countries such as those in Sub-Saharan Africa combines commonly used testing methods tailored to local levels of development and medical infrastructure, according to a study by researchers from and the University of Witwatersrand in South Africa and the University of North Carolina. Contact: William Davis
Public Release: 13-Jan-2013
Nature MedicinePill-sized device provides rapid, detailed imaging of esophageal lining Physicians may soon have a new way to screen patients for Barrett's esophagus, a precancerous condition usually caused by chronic exposure to stomach acid. Researchers at the Wellman Center for Photomedicine at Massachusetts General Hospital have developed an imaging system enclosed in a capsule about the size of a multivitamin pill that creates detailed, microscopic images of the esophageal wall.
National Institutes of Health
Contact: Sue McGreevey
Public Release: 13-Jan-2013
NatureFoot soldiers of the immune system Researchers at McGill University and the Research Center for Molecular Medicine of the Austrian Academy of Sciences have discovered the molecular blueprint behind the IFIT protein. This key protein enables the human immune system to detect viruses and prevent infection by acting as foot soldiers guarding the body against infection. The findings are a promising step towards developing new drugs for combating a wide range of immune system disorders. Contact: Cynthia Lee
Public Release: 13-Jan-2013
NatureCancer suppressor gene links metabolism with cellular aging The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, as opposed to ones based on enzymes. Now, researchers have identified a class of p53 target genes and regulatory molecules that represent more promising therapeutic candidates.
NIH/National Cancer Institute, Department of Defense
Contact: Karen Kreeger
Public Release: 11-Jan-2013
Proceedings of the National Academy of SciencesUGA discovery promises to improve drugs used to fight cancer, other diseases Even when at rest, the human body is a flurry of activity. Like a microscopic metropolis locked in a state of perpetual rush hour traffic, the trillions of cells that make us who we are work feverishly policing the streets, making repairs, building new structures and delivering important cargo throughout the bustling organic society. Contact: Natarajan Kannan
Showing releases 901-925 out of 1206. << < 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 > >>
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