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Public Release: 6-Jan-2016
Cell Metabolism
Scientists root out the 'bad seeds' of liver cancer
Researchers have found the 'bad seeds' of liver cancer and believe they could one day reprogram them to remain responsive to cancer treatment, a new USC study has found. The key to disrupting chemo-resistant stem cells that become liver tumors from multiplying is to target the stem cell marker NANOG, said Keigo Machida, senior author.
National Institutes of Health, Animal Core, Morphology Core, and Pilot Project Program, Non-Parenchymal Liver Cell Core, Research Scholar Grant, American Cancer Society

Contact: Zen Vuong
University of Southern California

Public Release: 6-Jan-2016
Human Molecular Genetics
Cancer drug shows promise for treating Duchenne muscular dystrophy
A drug commonly used to treat leukemia is showing potential as a treatment that could slow the progression of the muscle-wasting condition, Duchenne muscular dystrophy.
Muscular Dystrophy UK, Medical Research Council, Duchenne Parent Project NL

Contact: Beck Lockwood
University of Sheffield

Public Release: 6-Jan-2016
The Lancet
Winship multiple myeloma study in The Lancet
Winship multiple myeloma expert Sagar Lonial, M.D., played a key role in the testing of daratumumab (trade name Darzalex), which received accelerated approval from the US FDA in November 2015.
Janssen Biotech

Contact: Catherine Williams
Emory Health Sciences

Public Release: 6-Jan-2016
Cancer screening has never been shown to 'save lives,' argue experts
Cancer screening has never been shown to 'save lives' as advocates claim, argue experts in The BMJ today.

Contact: Emma Dickinson

Public Release: 6-Jan-2016
Cancer Discovery
New drug may overcome treatment resistance in a high-risk children's cancer
Pediatric oncologists from The Children's Hospital of Philadelphia have reported their latest results in devising new treatments for stubbornly deadly forms of the childhood cancer neuroblastoma. The 'unparalleled' strength of an ALK inhibitor in their preclinical studies, say the researchers, justifies fast-tracking the drug into pediatric clinical trials this year.
National Institutes of Health, US Army Peer Reviewed Medical Research Program

Contact: John Ascenzi
Children's Hospital of Philadelphia

Public Release: 6-Jan-2016
Contemporary Clinical Trials Communications
New open access journal highlights methods and clinical trial results
The first issue of Elsevier's new open access journal Contemporary Clinical Trials Communications features a new method to make cancer clinical trials more effective, a better way of determining whether a trial was successful and a dashboard that helps patients enroll in trials.

Contact: Jason Awerdick

Public Release: 6-Jan-2016
Science Translational Medicine
Early trial shows injectable agent illuminates cancer during surgery
Doctors at the Duke University School of Medicine have tested a new injectable agent that causes cancer cells in a tumor to fluoresce, potentially increasing a surgeon's ability to locate and remove all of a cancerous tumor on the first attempt. The imaging technology was developed through collaboration with scientists at Duke, the Massachusetts Institute of Technology and Lumicell Inc.
American Society of Clinical Oncology, National Institutes of Health, NIH/National Cancer Institute, NIH/National Center for Advancing Translational Science, Duke Comprehensive Cancer Center

Contact: Samiha Khanna
Duke University Medical Center

Public Release: 6-Jan-2016
Lung cancer clinical trial finds lung function without additional imaging
A newly NIH funded clinical trial by University of Colorado Cancer Center investigators and collaborators is evaluating a new method for pinpointing and sparing healthy lung tissue during lung cancer radiotherapy.
National Institutes of Health

Contact: Garth Sundem
University of Colorado Anschutz Medical Campus

Public Release: 6-Jan-2016
Human Gene Therapy
Proposed link between liver cancer and adeno-associated virus challenged in human gene therapy
The conclusion drawn from a recent study that insertion of adeno-associated virus 2 into human DNA causes mutations leading to the development of hepatocellular carcinoma was resoundingly rejected by leading researchers in the fields of gene therapy and molecular genetics. Calling the conclusions of the study authors 'an enormous leap from their data,' the team of researchers challenge details of the experimental methods, interpretation of the findings, and limitations of the study design in an Editorial published in Human Gene Therapy.

Contact: Kathryn Ryan
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 6-Jan-2016
DNA research offers clues on cell mutation
A Colorado State University team has found that RNA plays a new and important role in the DNA repair process.
NIH/Division of Intramural Research, NIH/National Institute of Environmental Health Sciences, Boettcher Foundation/Webb-Waring Biomedical Research Award, CNPq/Brazil, National Science Foundation/REU

Contact: Mary Guiden
Colorado State University

Public Release: 6-Jan-2016
16th IASLC World Conference on Lung Cancer
International CTCA study shows statins could be effective against small cell lung cancer
Researchers at Cancer Treatment Centers of America® (CTCA) at Western Regional Medical Center (Western), in collaboration with international colleagues, found that statins could be an effective therapeutic against metastatic small cell lung cancer. The study of 876 late-stage SCLC patients, published today in the scientific journal PLOS ONE, showed that statins, a class of drugs primarily used to lower cholesterol in patients at risk for heart disease, appeared to provide an increase in overall survival.
Hungarian Society of Pulmonology 2015/Lung Cancer Research Scholarship

Contact: Steve Yozwiak
Cancer Treatment Centers of America

Public Release: 6-Jan-2016
UC San Diego researchers link higher risk of leukemia to low sunlight and vitamin D
Epidemiologists at University of California, San Diego School of Medicine report that persons residing at higher latitudes, with lower sunlight/ultraviolet B (UVB) exposure and greater prevalence of vitamin D deficiency, are at least two times at greater risk of developing leukemia than equatorial populations.
University of California - San Diego Department of Family Medicine and Public Health

Contact: Scott LaFee
University of California - San Diego

Public Release: 6-Jan-2016
American Journal of Medicine
New FAU study suggests benefits of regular mammography extend to the elderly
Although a number of randomized trials demonstrate the clear benefits of mammography screening in women up to age 74 on reducing mortality, data are sparse in women over the age of 74, especially minorities. A new study shows that black and white women ages 75 to 84 years who had an annual mammogram had lower 10-year breast cancer mortality than corresponding women who had biennial or no/irregular mammograms.

Contact: Gisele Galoustian
Florida Atlantic University

Public Release: 5-Jan-2016
Long-term follow-up of risk of cancer among twins
In a long-term follow-up study among approximately 200,000 Nordic twin individuals, there was an increased cancer risk in twins whose co-twin was diagnosed with cancer, with an increased risk for cancer overall and for specific types of cancer, including prostate, melanoma, breast, ovary, and uterus, according to a study in the Jan. 5 issue of JAMA.

Contact: Lorelei A. Mucci
The JAMA Network Journals

Public Release: 5-Jan-2016
DHEA improves vaginal discomfort after menopause
A new phase III trial with positive results is taking intravaginal DHEA a step closer to governmental approval. The formulation could provide women who cannot or do not wish to use intravaginal estrogen with an effective vaginal alternative for easing vaginal symptoms and pain with sex after menopause. The trial results were published online today in Menopause, the journal of The North American Menopause Society.

Contact: Eileen Petridis
The North American Menopause Society (NAMS)

Public Release: 5-Jan-2016
Twin study estimates familial risks of 23 different cancers
A large new study of twins has found that having a twin sibling diagnosed with cancer poses an excess risk for the other twin to develop any form of cancer.
Ellison Foundation to Harvard T.H. Chan School of Public Health, Nordic Cancer Union

Contact: Todd Datz
Harvard T.H. Chan School of Public Health

Public Release: 5-Jan-2016
International Journal of Radiation Oncology, Biology, Physics
Radiation an important addition to treatment for pancreatic cancer surgery candidates
Radiation therapy was associated with a lower risk of cancer recurrence in pancreatic cancer surgery patients, making it, like chemotherapy, an important addition to treatment, Mayo Clinic research found.

Contact: Sharon Theimer
Mayo Clinic

Public Release: 5-Jan-2016
Nature Communications
CNIO finds a possible new pharmacological target for one of the most important and elusive oncogenes
MYC is altered in more than half of human cancers, and it is often associated with very aggressive tumors. Researchers have identified a second gene, called BPTF, that has an important role in the chain of molecular events that allow MYC to function, therefore revealing itself as a possible new therapeutic target.

Contact: Vanessa Pombo
Centro Nacional de Investigaciones Oncológicas (CNIO)

Public Release: 5-Jan-2016
Association for Cancer Physicians releases cancer patient strategy for UK
The Association for Cancer Physicians, which represents and supports medical oncologists in the UK, has published a new strategy for improving cancer patient services and outcomes.

Contact: Audrey Nailor

Public Release: 5-Jan-2016
Proceedings of the National Academy of Sciences
Novel RNA delivery system may treat incurable blood cancers
Mantle Cell Lymphoma is considered the most aggressive known blood cancer, and available therapies are scarce. A new study by Tel Aviv University researchers offers tangible hope of curing the currently incurable cancer -- and others like it.

Contact: George Hunka
American Friends of Tel Aviv University

Public Release: 4-Jan-2016
Journal of Urology
Prostate cancer surveillance criteria may not be accurate for African American men
A new study published in The Journal of Urology revealed that African American men with Gleason score 3+3=6 prostate cancer (PCa) produce less prostate specific antigen (PSA) and have significantly lower PSA density (PSAD) than Caucasian men. These findings could have important implications when selecting patients for inclusion in active PCa surveillance programs.

Contact: Linda Gruner
Elsevier Health Sciences

Public Release: 4-Jan-2016
BJU International
Prostate surgery patients may have unrealistic expectations concerning their recovery
Patients who have undergone radical prostatectomy often have largely unrealistic expectations with regard to their postoperative sexual function, new research shows.

Contact: Dawn Peters

Public Release: 4-Jan-2016
Journal of Hunger & Environmental Nutrition
Miriam Hospital, R.I. Community Food Bank study dispels belief healthy diets are costly
Research conducted by The Miriam Hospital and The Rhode Island Community Food Bank demonstrated that -- contrary to popular belief -- healthy diets rich in fruits and vegetables are affordable.

Contact: Elena Falcone-Relvas

Public Release: 4-Jan-2016
Annals of Neurology
Medical research influenced by training 'genealogy'
By analyzing peer-reviewed scientific papers that examined the effectiveness of a surgical procedure, researchers at University of California, San Diego School of Medicine provide evidence suggesting that the conclusions of these studies appear to be influenced by the authors' mentors and medical training.
UC San Diego/Czech Duck Research Fellowship in Neurosurgery

Contact: Heather Buschman
University of California - San Diego

Public Release: 4-Jan-2016
Journal of Thoracic Oncology
Improving access to clinical trials when biopsies are required
The requirement for tumor tissue specimens and associated analyses in order to participate in clinical trials appears to be a significant barrier to clinical trial enrollment and may delay treatment. Potential solutions to reducing or eliminating these barriers include routine tissue banking at diagnosis, easing use of available diagnostic samples, development of less invasive tests, faster turnaround time at central laboratories or allowing for local testing and more resources for timely tissue collection.

Contact: Jeff Wolf
International Association for the Study of Lung Cancer

Showing releases 901-925 out of 1300.

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