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Showing releases 901-925 out of 1242.

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Public Release: 9-Jun-2014
Most breast cancer patients may not be getting enough exercise
Physical activity after breast cancer diagnosis has been linked with prolonged survival and improved quality of life, but most participants in a large breast cancer study did not meet national physical activity guidelines after they were diagnosed.

Contact: Evelyn Martinez

Public Release: 9-Jun-2014
Journal of Clinical Investigation
Resistance to lung cancer targeted therapy can be reversed, study suggests
Up to 40 percent of lung cancer patients do not respond to a targeted therapy designed to block tumor growth -- a puzzling clinical setback that researchers have long tried to solve. Now, scientists have discovered why that intrinsic resistance occurs -- and they pinpoint a drug they say could potentially reverse it.

Contact: Karen Teber
Georgetown University Medical Center

Public Release: 9-Jun-2014
2014 SNMMI Annual Meeting
Radioluminescence tells the story of single cells
With a new molecular imaging system powerful enough to peer down to 20-micrometer resolution, researchers can now use radioluminescence to examine the characteristics of single, unconnected cells. The result is a fascinating picture of diversity among cells previously assumed to behave the same, revealed researchers at the Society of Nuclear Medicine and Molecular Imaging's 2014 Annual Meeting.

Contact: Kimberly Brown
Society of Nuclear Medicine

Public Release: 9-Jun-2014
Nature Communications
UNC researchers pinpoint new role for enzyme in DNA repair, kidney cancer
Twelve years ago, UNC School of Medicine researcher Brian Strahl, PhD, found that a protein called Set2 plays a role in how yeast genes are expressed -- specifically how DNA gets transcribed into messenger RNA. Now his lab has found that Set2 is also a major player in DNA repair, a complicated and crucial process that can lead to the development of cancer cells if the repair goes wrong.
National Institutes of Health

Contact: Mark Derewicz
University of North Carolina Health Care

Public Release: 9-Jun-2014
Annals of Internal Medicine
News from Annals of Internal Medicine tip sheet -- June 10, 2014
The June 10 issue of Annals of Internal Medicine contains articles titled 'Increase screening rates to prevent cervical cancer, experts suggest' and 'Experts explain merits and shortcomings of Medicare data release.'

Contact: Megan Hanks
American College of Physicians

Public Release: 9-Jun-2014
Annals of Internal Medicine
What's the best test for cervical cancer? Pap, HPV or both?
Should US women be screened for cervical cancer with Pap tests, HPV tests or both? According to researchers from Boston University School of Medicine and Boston Medical Center while the merits of screening tests and screening intervals warrant further discussion, they firmly believe that increasing the number of women who participate in cancer screenings and ensuring that women are not lost to follow-up with lengthened screening intervals is more important than the choice of test to decrease rates of cervical cancer.

Contact: Gina DiGravio
Boston University Medical Center

Public Release: 9-Jun-2014
2014 SNMMI Annual Meeting
Chemo-radionuclide therapy halts neuroendocrine cancer
Advanced cancer of the neuroendocrine system can lead to dismal prognoses, but a novel therapy is packing a punch by uniting powerful radionuclide treatment and chemotherapy drugs, revealed researchers at the Society of Nuclear Medicine and Molecular Imaging's 2014 Annual Meeting.

Contact: Kimberly Brown
Society of Nuclear Medicine

Public Release: 9-Jun-2014
Journal of Experimental Medicine
Combination therapy may help patients with follicular lymphoma
Follicular lymphoma is an incurable form of non-Hodgkin lymphoma that is diagnosed each year in 120,000 people worldwide. Researchers show that a high-risk group of patients with the disease could benefit from a novel drug combination.
NIH/National Cancer Institute, American Cancer Society, Leukemia Research Foundation, and others

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 8-Jun-2014
Nature Genetics
Longer telomeres linked to risk of brain cancer
New genomic research led by UC San Francisco scientists reveals that two common gene variants that lead to longer telomeres, the caps on chromosome ends thought by many scientists to confer health by protecting cells from aging, also significantly increase the risk of developing the deadly brain cancers known as gliomas.
National Institutes of Health, National Brain Tumor Foundation, University of California, San Francisco

Contact: Peter Farley
University of California - San Francisco

Public Release: 8-Jun-2014
Nature Chemical Biology
New molecule enables quick drug monitoring
Scientists at EPFL have invented a molecule that can easily and quickly show how much drug is in a patient's system. The molecule, now the basis of a start-up company, is expected to enable point-of-care therapeutic drug monitoring.
École polytechnique fédérale de Lausanne, Swiss National Science Foundation, National Centre of Competence in Research Chemical Biology, Defense Threat Reduction

Contact: Nik Papageorgiou
Ecole Polytechnique Fédérale de Lausanne

Public Release: 8-Jun-2014
Nature Materials
Targeting tumors using silver nanoparticles
Scientists at UC Santa Barbara have designed a nanoparticle that has a couple of unique -- and important -- properties. Spherical in shape and silver in composition, it is encased in a shell coated with a peptide that enables it to target tumor cells. What's more, the shell is etchable so those nanoparticles that don't hit their target can be broken down and eliminated. The research findings appear today in the journal Nature Materials.

Contact: Julie Cohen
University of California - Santa Barbara

Public Release: 8-Jun-2014
Health Affairs
Health Affairs asks: Where can we find savings in health care?
The June issue of Health Affairs features various approaches to cost savings in the US health care system, and several other articles that may be of interest to the global community.

Contact: Sue Ducat
Health Affairs

Public Release: 6-Jun-2014
Journal of Virology
Herpesviruses undercover
Pathogens entering our body only remain unnoticed for a short period. Within minutes our immune cells detect the invader and trigger an immune response. However, some viruses have developed strategies to avoid detection and elimination by our immune system. Researchers from the Helmholtz Centre for Infection Research in Braunschweig have now been able to show how the herpesviruses achieve this.

Contact: Rebecca Winkels
Helmholtz Centre for Infection Research

Public Release: 6-Jun-2014
Endocrine-Related Cancer
Prostate cancer biomarkers identified in seminal fluid
Improved diagnosis and management of one of the most common cancers in men -- prostate cancer -- could result from research at the University of Adelaide, which has discovered that seminal fluid contains biomarkers for the disease.
Prostate Cancer Foundation

Contact: Dr. Luke Selth
University of Adelaide

Public Release: 6-Jun-2014
Journal of Molecular Diagnostics
Biomarkers accurately distinguish mesothelioma from non-cancerous tissue
Scientists have identified four biomarkers that may help resolve the difficult differential diagnosis between malignant pleural mesothelioma (MPM) and non-cancerous pleural tissue with reactive mesothelial proliferations. This is a frequent differential diagnostic problem in pleural biopsy samples taken from patients with clinical suspicion of MPM. The ability to make more accurate diagnoses earlier may facilitate improved patient outcomes. This new study appears in the Journal of Molecular Diagnostics.

Contact: Eileen Leahy
Elsevier Health Sciences

Public Release: 6-Jun-2014
Scientists reveal details of calcium 'safety-valve' in cells
The New York Consortium on Membrane Protein Structure used X-rays at Brookhaven Lab's National Synchrotron Light Source to decipher the atomic level structure of a protein that regulates the level of calcium in cells, providing clues about a key signaling agent that can trigger programmed cell death and potentially leading to new anticancer drug targets.
National Institutes of Health, US Department of Energy

Contact: Karen McNulty Walsh
DOE/Brookhaven National Laboratory

Public Release: 6-Jun-2014
Clinical Gastroenterology and Hepatology
Probiotics prevent deadly complications of liver disease
Probiotics are effective in preventing hepatic encephalopathy in patients with cirrhosis of the liver, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

Contact: Rachel Steigerwald
American Gastroenterological Association

Public Release: 6-Jun-2014
Gastrointestinal Endoscopy
Endoscope with an oxygen sensor detects pancreatic cancer
An optical blood oxygen sensor attached to an endoscope is able to identify pancreatic cancer in patients via a simple lendoscopic procedure, according to researchers at Mayo Clinic in Florida.
National Institutes of Health, NIH/National Cancer Institute, Mayo Clinic Foundation for Medical Education & Research

Contact: Kevin Punsky
Mayo Clinic

Public Release: 5-Jun-2014
European Society for Medical Oncology World Conference on Gastrointestinal Cancer
New therapy for pancreatic cancer patients shows promising results
A clinical trial conducted by researchers at the Virginia G. Piper Cancer Center Clinical Trials, a partnership between Scottsdale Healthcare and the Translational Genomics Research Institute, showed that a new drug called MM-398, given in combination with 5-flourouracil and leucovorin, produced a significant overall survival rate in patients with advanced, previously-treated pancreatic cancer.
Merrimack Pharmaceuticals

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 5-Jun-2014
Cell Stem Cell
Stem cells hold keys to body's plan
Case Western Reserve researchers have discovered landmarks within pluripotent stem cells that guide how they develop to serve different purposes within the body. This breakthrough offers promise that scientists eventually will be able to direct stem cells in ways that prevent disease or repair damage from injury or illness. The study and its results appear in the June 5 edition of the journal Cell Stem Cell.
National Institutes of Health, New York Stem Cell Foundation, Mount Sinai Health Care Foundation, Case Comprehensive Cancer Center, Case Western Reserve University

Contact: Jeannette Spalding
Case Western Reserve University

Public Release: 5-Jun-2014
Brain circuit problem likely sets stage for the 'voices' that are symptom of schizophrenia
St. Jude Children's Research Hospital scientists have identified problems in a connection between brain structures that may predispose individuals to hearing the 'voices' that are a common symptom of schizophrenia. The work appears in the June 6 issue of the journal Science.
National Institutes of Health, American-Lebanese-Syrian Associated Charities

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Public Release: 5-Jun-2014
MAD: Scientists shed light on braking mechanisms in cellular signaling
A team of researchers studying a flowering plant has zeroed in on the way cells manage external signals about prevailing conditions, a capability that is essential for cells to survive in a fluctuating environment.

Contact: Zhiyong Wang
Carnegie Institution

Public Release: 5-Jun-2014
Cancer Discovery
Seemingly invincible cancers stem cells reveal a weakness
Metastatic cancer cells, which can migrate from primary tumors to seed new malignancies, have thus far been resistant to the current arsenal of anticancer drugs. Now, however, researchers at Whitehead Institute have identified a critical weakness that actually exploits one of these cells' apparent strengths -- their ability to move and invade tissues. Their research could inform novel approaches to screening tumors for personalized therapy or to drugs that specifically target these cells.
Richard and Susan Smith Family Foundation, Breast Cancer Alliance

Contact: Nicole Giese Rura
Whitehead Institute for Biomedical Research

Public Release: 5-Jun-2014
Scientists find new targets that could increase effectiveness of breast cancer treatments
Scientists from the Florida campus of the Scripps Research Institute have found new targets for potential intervention in breast cancer. These new targets could eventually increase effectiveness and reduce the undesirable side effects associated with current treatments.
National Institutes of Health, NIH/National Cancer Institute

Contact: Eric Sauter
Scripps Research Institute

Public Release: 5-Jun-2014
Analytical Chemistry
Research could lead to new cancer assay, aid both dogs and humans
Veterinary researchers have identified a unique group of proteins that indicate the presence of transitional cell carcinoma -- the most common cause of bladder cancer -- and may lead to a new assay which could better diagnose this disease in both dogs and humans.
NIH/National Insitutes of Environmental Health Sciences

Contact: Shay Bracha
Oregon State University

Showing releases 901-925 out of 1242.

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