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Public Release: 23-May-2014
Scientific Reports
New sensor could light the way forward in low-cost medical imaging
New research published today in Nature's Scientific Reports, identifies a new type of light sensor that could allow medical and security imaging, via low cost cameras.

Contact: Amy Sutton
University of Surrey

Public Release: 22-May-2014
Nature Communications
Scientists find new way to combat drug resistance in skin cancer
Rapid resistance to vemurafenib -- a treatment for a type of advanced melanoma, the deadliest form of skin cancer -- could be prevented by blocking a druggable family of proteins, according to research published in Nature Communications.
Cancer Research UK

Contact: Simon Shears
Cancer Research UK

Public Release: 22-May-2014
CA: A Cancer Journal for Clinicians
Review says inexpensive food a key factor in rising obesity
A new review identifies an important factor fueling the obesity epidemic: Americans now have the cheapest food available in history.
National Institutes of Health, RAND

Contact: David Sampson
American Cancer Society

Public Release: 22-May-2014
Discovery of how Taxol works could lead to better anticancer drugs
Taxol, one of the most widely used anticancer drugs, interferes with the splitting of cells, preferentially killing actively dividing cancer cells. A UC Berkeley team led by biophysicist Eva Nogales has discovered how Taxol works. The drug binds to microtubules, part of the cell's skeleton, and prevents compaction of the tubulin subunits, which normally spring-loads the molecule so that it rapidly peels apart when required. Taxol prevents that peeling, immobilizing microtubules and killing the cell.
NIH/National Institute of General Medical Sciences, Damon Runyon, Howard Hughes Medical Institute

Contact: Robert Sanders
University of California - Berkeley

Public Release: 22-May-2014
Cancer Cell
Study: Some pancreatic cancer treatments may be going after the wrong targets
New research represents a significant change in the understanding of how pancreatic cancer grows -- and how it might be defeated.
National Institutes of Health, American Gastroenterological Association/Foundation for Digestive Health and Nutrition

Contact: Nicole Fawcett
University of Michigan Health System

Public Release: 22-May-2014
Cancer Cell
Supportive tissue in tumors hinders, rather than helps, pancreatic cancer
Study finds that fibrosis is part of the body's effort to contain and thwart pancreatic cancer. When it's stopped, the disease progresses faster, which aligns with clinical trial results.
NIH/National Cancer Institute, Cancer Prevention and Research Institute of Texas

Contact: Scott Merville
University of Texas M. D. Anderson Cancer Center

Public Release: 22-May-2014
RaDAR guides proteins into the nucleus
A Ludwig Cancer Research study has identified a novel pathway by which proteins are actively and specifically shuttled into the nucleus of a cell. Published online today in Cell, the finding captures a precise molecular barcode that flags proteins for such import and describes the biochemical interaction that drives this critically important process. The discovery could help illuminate the molecular dysfunction that underpins a broad array of ailments, ranging from autoimmune diseases to cancers.
Ludwig Institute for Cancer Research

Contact: Rachel Steinhardt
Ludwig Institute for Cancer Research

Public Release: 22-May-2014
Proceedings of the National Academy of Sciences
Signals found that recruit host animals' cells, enabling breast cancer metastasis
Working with mice, Johns Hopkins researchers report they have identified chemical signals that certain breast cancers use to recruit two types of normal cells needed for the cancers' spread. A description of the findings appears in the online early May edition of the Proceedings of the National Academy of Sciences.
American Cancer Society, NIH/National Cancer Institute

Contact: Shawna Williams
Johns Hopkins Medicine

Public Release: 22-May-2014
New details on microtubules and how the anti-cancer drug Taxol works
Berkeley Lab researchers have produced images of microtubule assembly and disassembly at the unprecedented resolution of 5 angstroms, providing new insight into the success of the anti-cancer drug Taxol and pointing the way to possible improvements.
National Institutes of Health

Contact: Lynn Yarris
DOE/Lawrence Berkeley National Laboratory

Public Release: 22-May-2014
Cell Reports
Researchers identify key mechanism in metabolic pathway that fuels cancers
A UT Southwestern research team has taken a significant step in cracking the code of an atypical metabolic pathway that allows certain cancerous tumors to thrive, providing a possible roadmap for defeating such cancers.

Contact: Mark Lane
UT Southwestern Medical Center

Public Release: 22-May-2014
Clinical trials designed to block autophagy in multiple cancers show promise
In the largest group of results to date, researchers from Penn Medicine's Abramson Cancer Center and other institutions have shown in clinical trials that the malaria drug hydroxychloroquine blocked autophagy in a host of aggressive cancers -- glioblastoma, melanoma, lymphoma and myeloma, renal and colon cancers -- and in some cases helped stabilize disease.

Contact: Steve Graff
University of Pennsylvania School of Medicine

Public Release: 22-May-2014
Which way is up?
The Denise Montell Lab used fruit-fly ovaries to uncover how E-cadherin guides collective cell migration.

Contact: Julie Cohen
University of California - Santa Barbara

Public Release: 22-May-2014
Yale Cancer Center studies find lifestyle changes improve biomarkers for breast cancer recurrence and mortality
A pair of Yale Cancer Center interventional studies involving breast cancer survivors found that lifestyle changes in the form of healthy eating and regular exercise can decrease biomarkers related to breast cancer recurrence and mortality. The abstracts are scheduled to be presented at the 2014 annual meeting of the American Society of Clinical Oncology in Chicago May 30-June 3rd.

Contact: Vicky Agnew
Yale University

Public Release: 21-May-2014
ASCO 50th Annual Meeting
EORTC to present cancer research results at ASCO 2014
The EORTC will present nine abstracts at the ASCO 2014 Annual Meeting which will be held May 30-June 3, 2014, in Chicago, Ill. Four abstracts will be presented in Oral Abstract Sessions, one in a Poster Highlights Session, and another four in General Poster Sessions.

Contact: John Bean
European Organisation for Research and Treatment of Cancer

Public Release: 21-May-2014
Molecular Cancer Research
Molecule linked to aggressive pancreatic cancer offers potential clinical advances
Mayo Clinic researchers have discovered an enzyme they say is tightly linked to how aggressive pancreatic cancer will be in a patient.
NIH/National Cancer Institute, Mayo Clinic SPORE in Pancreatic Cancer

Contact: Kevin Punsky
Mayo Clinic

Public Release: 21-May-2014
JAMA Surgery
Study examines prophylactic double mastectomy following breast cancer diagnosis
Many women diagnosed with cancer in one breast consider, and eventually undergo, a contralateral prophylactic mastectomy to remove both breasts, although few of them have a clinically significant risk of developing cancer in both breasts.

Contact: Nicole Fawcett
The JAMA Network Journals

Public Release: 21-May-2014
JAMA Surgery
Most women who have double mastectomy don't need it, U-M study finds
About 70 percent of women who have both breasts removed following a breast cancer diagnosis do so despite a very low risk of facing cancer in the healthy breast, new research from the University of Michigan Comprehensive Cancer Center finds.
NIH/National Cancer Institute

Contact: Nicole Fawcett
University of Michigan Health System

Public Release: 21-May-2014
Molecular Cancer Therapeutics
Finnish researchers discovered a new anticancer compound
A team of research scientists from VTT Technical Research Centre of Finland, the University of Turku and the University of Eastern Finland has discovered a previously unknown Cent-1 molecule that kills cancer cells.

Contact: Marko Kallio
VTT Technical Research Centre of Finland

Public Release: 21-May-2014
Journal of Translational Medicine
Cancer avatars for personalized medicine
Researchers at University of California, San Diego School of Medicine and Moores Cancer Center have used computer simulations of cancer cells -- cancer avatars -- to identify drugs most likely to kill cancer cells isolated from patients' brain tumors.
National Brain Tumor Society, Barbara and Joseph Ajello Trust Fund, Tuttleman Family Foundation

Contact: Scott LaFee
University of California - San Diego

Public Release: 21-May-2014
Drug-target database lets researchers match old drugs to new uses
A study recently published in the journal Bioinformatics describes a new database and pattern-matching algorithm that allows researchers to evaluate rational drugs and drug combinations, and also recommends a new drug combination to treat drug-resistant non-small cell lung cancer.
National Institutes of Health

Contact: Garth Sundem
University of Colorado Denver

Public Release: 21-May-2014
Molecule acts as umpire to make tough life-or-death calls
Researchers have demonstrated that an enzyme required for animal survival after birth functions like an umpire, making the tough calls required for a balanced response to signals that determine if cells live or die. St. Jude Children's Research Hospital scientists led the study, which was published online and appears in the May 22 edition of the scientific journal Cell.
National Institutes of Health, ALSAC

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Public Release: 21-May-2014
Cell Reports
TSRI scientists catch misguided DNA-repair proteins in the act
Scientists led by a group of researchers at The Scripps Research Institute in La Jolla, CA, have discovered some of the key proteins involved in one type of DNA repair gone awry.
Pew Scholars, National Institutes of Health, Novartis Advanced Discovery Institute, Italian Ministry of Health, FIRC

Contact: Madeline McCurry Schmidt
Scripps Research Institute

Public Release: 21-May-2014
Journal of Urology
Study shows image fusion-guided biopsy improves accuracy of prostate cancer diagnosis
The detection rate is twice as high using MRI and ultrasound fusion-guided biopsy.

Contact: Betty Olt
North Shore-Long Island Jewish (LIJ) Health System

Public Release: 21-May-2014
Nature Chemical Biology
Team validates potentially powerful new way to treat HER2-positive breast cancer
A CSHL-led research team reports that it has found a means of inhibiting a protein called PTP1B, whose expression is upregulated in HER2-positive breast cancer. They show that PTP1B plays a critical role in the development of tumors in which HER2 signaling is aberrant. Therefore, PTP1B may be a therapeutic target via which to treat the disease.
National Institutes of Health, Cold Spring Harbor Laboratory Cancer Center, American Diabetes Association

Contact: Peter Tarr
Cold Spring Harbor Laboratory

Public Release: 21-May-2014
International Journal of Cancer
The interruption of biological rhythms during chemotherapy worsen its side effects
Patients receiving chemical treatment for cancer often suffer fatigue and body weight loss, two of the most worrying effects of this therapy linked to the alteration of their circadian rhythms.

Contact: Press Office
FECYT - Spanish Foundation for Science and Technology

Showing releases 901-925 out of 1259.

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