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Public Release: 16-Jul-2014
Journal of the National Cancer Institute
Marginal life expectancy benefit from contralateral prophylactic mastectomy
The choice of contralateral prophylactic mastectomy by women with breast cancer diagnosed in one breast has recently increased in the US but may confer only a marginal life expectancy benefit depending on the type and stage of cancer, according to a study published July 16 in the JNCI: Journal of the National Cancer Institute.

Contact: Zachary Rathner
Oxford University Press USA

Public Release: 16-Jul-2014
European Urology
Study: Robot-assisted surgery for prostate cancer controls the disease for 10 years
Robot-assisted surgery to remove cancerous prostate glands is effective in controlling the disease for 10 years, according to a new study led by researchers at Henry Ford Hospital. The study also suggested that traditional methods of measuring the severity and possible spread of the cancer together with molecular techniques might, with further research, help to create personalized, cost-effective treatment regimens for prostate cancer patients who undergo the surgical procedure.
Vattikuti Urology Institute

Contact: Dwight Angell
Henry Ford Health System

Public Release: 16-Jul-2014
Nicotine and Tobacco Research
Study: Smoking may contribute to suicide risk
Cigarette smokers are more likely to commit suicide than people who don't smoke, a relationship that has been attributed to the fact that numerous people with psychiatric disorders, who have higher suicide rates, also tend to smoke. But a new study by researchers at Washington University School of Medicine in St. Louis finds that smoking itself may increase suicide risk and that policies to limit smoking reduce suicide rates.
American Foundation for Suicide Prevention, NIH/National Institute on Drug Abuse, NIH/National Cancer Institute, American Cancer Society.

Contact: Jim Dryden
Washington University School of Medicine

Public Release: 16-Jul-2014
Journal of the National Cancer Institute
Screening costs increased in older women without changing detection rates of ESBC
Medicare spending on breast cancer screening increased substantially between 2001 and 2009 but the detection rates of early stage tumors were unchanged, according to a new study published July 16 in the JNCI: Journal of the National Cancer Institute.

Contact: Zachary Rathner
Oxford University Press USA

Public Release: 16-Jul-2014
New England Journal of Medicine
Promising medication counteracts constipation caused by opioid painkillers
Opioids -- strong morphine-based painkillers -- are widely prescribed to patients experiencing chronic severe pain. While these drugs are very effective for treating and managing pain, they have one particularly bothersome side effect: constipation. A new drug, called naloxegol, could bring relief. In stage 3 trials reported in the New England Journal of Medicine, KU Leuven and international researchers provide new evidence that the drug relieves constipation without dulling opioids' pain-relieving effects.

Contact: Jan Tack
KU Leuven

Public Release: 16-Jul-2014
Angewandte Chemie
Self-assembling nanoparticle could improve MRI scanning for cancer diagnosis
Scientists have designed a new self-assembling nanoparticle that targets tumours, to help doctors diagnose cancer earlier.
Cancer Research UK, Engineering and Physical Sciences Research Council, Medical Research Council, Department of Health

Contact: Gail Wilson
Imperial College London

Public Release: 15-Jul-2014
Physics in Medicine and Biology
How strongly does tissue decelerate the therapeutic heavy ion beam?
Cancer treatment with heavy ion irradiation: Scientists of the Physikalisch-Technische Bundesanstalt in Germany have established an experiment for the more exact determination of the stopping power of tissue for carbon ions in the therapeutically relevant area which is so far unique worldwide. This can contribute to clearly improving the dosing for cancer therapy with carbon ions.

Contact: Woon Yong Baek
Physikalisch-Technische Bundesanstalt (PTB)

Public Release: 15-Jul-2014
Science Signaling
Neurons, brain cancer cells require the same little-known protein for long-term survival
Researchers at the UNC School of Medicine have discovered that the protein PARC/CUL9 helps neurons and brain cancer cells override the biochemical mechanisms that lead to cell death in most other cells. In neurons, long-term survival allows for proper brain function as we age. In brain cancer cells, though, long-term survival contributes to tumor growth and the spread of the disease.
National Institutes of Health, American Heart Association, American Brain Tumor Association, Michael J. Fox Foundation for Parkinson's Research

Contact: Mark Derewicz
University of North Carolina Health Care

Public Release: 15-Jul-2014
Clinical Cancer Research
New skin gel fights breast cancer without blood clot risk
A gel form of tamoxifen applied to the breasts of women with noninvasive breast cancer reduced the growth of cancer cells equally to the oral drug but with fewer side effects that deter some women from taking it. The gel is intended to minimize blood clots and uterine cancer risk. Tamoxifen is used for breast cancer prevention and for cancer treatment.
National Cancer Institute

Contact: Marla Paul
Northwestern University

Public Release: 15-Jul-2014
Annals of Surgery
Saltier intravenous fluids reduce complications from surgery
Infusing a saltier saline solution during and after surgery decreases overall complication rate for a complex procedure.

Contact: Edyta Zielinska
Thomas Jefferson University

Public Release: 15-Jul-2014
Nature Communications
Cholesterol activates signaling pathway that promotes cancer
Everyone knows that cholesterol, at least the bad kind, can cause heart disease and hardening of the arteries. Now, researchers at the University of Illinois at Chicago describe a new role for cholesterol in the activation of a cellular signaling pathway that has been linked to cancer.
National Institutes of Health, World Class University program, National Research Foundation of Korea

Contact: Sharon Parmet
University of Illinois at Chicago

Public Release: 15-Jul-2014
Nature Reviews Urology
Prostate cancer in young men -- More frequent and more aggressive?
The number of younger men diagnosed with prostate cancer has increased nearly 6-fold in the last 20 years, and the disease is more likely to be aggressive in these younger men, according to a new analysis from researchers at the University of Michigan Comprehensive Cancer Center.
National Cancer Institute

Contact: Nicole Fawcett
University of Michigan Health System

Public Release: 15-Jul-2014
American Journal of Preventive Medicine
4 lessons for effective, efficient research in health care settings
University of Colorado Cancer Center study shows that by taking into account the real-world constraints of the systems in which providers deliver care and patients receive it, researchers can help speed results, cut costs, and increase chances that recommendations from their findings will be implemented.

Contact: Garth Sundem
University of Colorado Denver

Public Release: 15-Jul-2014
Molecular Cell
New UK study helps scientists understand melanoma development
A new study by University of Kentucky researchers shows how a genetic defect in a specific hormonal pathway may make people more susceptible to developing melanoma, the deadliest type of skin cancer.
National Institutes of Health, Drury Pediatric Research Endowed Chair Fund, Wendy Will Case Cancer Research Fund, Markey Cancer Foundation, Children's Miracle Network, Jennifer and David Dickens Melanoma Research Foundation

Contact: Allison Perry
University of Kentucky

Public Release: 15-Jul-2014
Interface Focus
Game theory model reveals vulnerable moments for cancer cells' energy production
Cancer's no game, but researchers at Johns Hopkins are borrowing ideas from evolutionary game theory to learn how cells cooperate within a tumor to gather energy. Their experiments, they say, could identify the ideal time to disrupt metastatic cancer cell cooperation and make a tumor more vulnerable to anti-cancer drugs.
NIH/National Cancer Institute

Contact: Vanessa Wasta
Johns Hopkins Medicine

Public Release: 14-Jul-2014
Nature Communications
Wisconsin scientists find genetic recipe to turn stem cells to blood
The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality. Writing today in the journal Nature Communications, a group led by University of Wisconsin-Madison stem cell researcher Igor Slukvin reports the discovery of two genetic programs responsible for taking blank-slate stem cells and turning them into both red and the array of white cells that make up human blood.
National Institutes of Health, Charlotte Geyer Foundation

Contact: Igor Slukvin
University of Wisconsin-Madison

Public Release: 14-Jul-2014
Testicular cancer rates are on the rise in young Hispanic Americans
A new analysis has found that rates of testicular cancer have been rising dramatically in recent years among young Hispanic American men, but not among their non-Hispanic counterparts.

Contact: Evelyn Martinez

Public Release: 14-Jul-2014
Annals of Family Medicine
Bonuses for doctors do little to improve cancer screening in Ontario
Ontario spent nearly $110 million dollars between 2006 and 2010 on bonuses to motivate family doctors to screen more of their patients for cancer but these bonuses were associated with little or no improvement in actual cancer screening rates, according to researchers at St. Michael's Hospital and the Institute for Clinical Evaluative Sciences.

Contact: Geoff Koehler
416-864-6060 x6537
St. Michael's Hospital

Public Release: 14-Jul-2014
Journal of Biological Chemistry
UEA research reveals how cannabis compound could slow tumour growth
Scientists at the University of East Anglia have shown how the main psychoactive ingredient in cannabis could reduce tumor growth in cancer patients. Research published today reveals the existence of previously unknown signaling platforms which are responsible for the drug's success in shrinking tumours. It is hoped that the findings could help develop a synthetic equivalent with anti-cancer properties.

Contact: Lisa Horton
University of East Anglia

Public Release: 14-Jul-2014
JAMA Internal Medicine
Prostate cancer is focus of 2 studies, commentary
Management of low-risk prostate cancer, which is unlikely to cause symptoms or affect survival if left untreated, varies widely among urologists and radiation oncologists, with patients whose diagnosis is made by a urologist that treats non-low-risk prostate cancer more likely to receive treatment vs. observation.

Contact: William B. Fitzgerald
The JAMA Network Journals

Public Release: 14-Jul-2014
JAMA Internal Medicine
Study finds diagnosing physicians influence therapy decisions for prostate cancer patients
New research from The University of Texas MD Anderson Cancer Center is shedding light on the important role a diagnosing urologist plays in whether older men with low-risk prostate cancer receive treatment for their disease, and if so, the type of treatment they receive as a result.

Contact: William Fitzgerald
University of Texas M. D. Anderson Cancer Center

Public Release: 14-Jul-2014
Proceedings of the National Academy of Sciences
New combination drug controls tumor growth and metastasis in mice
Researchers at UC Davis, University of Massachusetts and Harvard Medical School have created a combination drug that controls both tumor growth and metastasis. By combining a COX-2 inhibitor, similar to Celebrex, and an epoxide hydrolase inhibitor, the drug controls angiogenesis, limiting a tumor's ability to grow and spread.
NIH/National Institute of Environmental Health Scien, Superfund, NIH/National Institute for Occupational Safety, Stop and Shop Pediatric Brain Tumor Fund, C.J. Buckley Pediatric Brain Tumor Fund, US Department of Veterans Affairs, American Asthma Society

Contact: Dorsey Griffith
University of California - Davis Health System

Public Release: 14-Jul-2014
Proceedings of the National Academy of Sciences
Capturing cancer: A powerful new technique for early diagnosis
In research appearing in today's issue of the journal Proceedings of the National Academy of Science, Stafford and his team describe an innovative technique for early disease detection, which they call immunosignaturing.

Contact: Joseph Caspermeyer
Arizona State University

Public Release: 14-Jul-2014
Scientists developed new technology for the diagnosis of cancer cells
The type of therapy a cancer patient receives, largely depends on the eye of a pathologist. However, human judgment is, by its very nature, subject to variation. To enhance the quality of diagnosis, scientists at Vetmeduni Vienna, the Medical University of Vienna and the Ludwig Boltzmann Institute for Cancer Research have developed a software that identifies cell structures and proteins in order to provide reliable diagnoses. The data was published in the journal PLOS ONE.

Contact: Lukas Kenner
University of Veterinary Medicine -- Vienna

Public Release: 14-Jul-2014
Biophysical Reviews and Letters
Cancer is avoidable as you grow older. Here's how.
Although it is widely thought that cancer is an inevitable consequence of aging, the risk of developing several common cancers decreases with age.

Contact: Jason Lim Chongjin
65-646-65775 x247
World Scientific

Showing releases 901-925 out of 1275.

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