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Showing releases 926-950 out of 1296.

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Public Release: 13-Jul-2014
Antibody halts cancer-related wasting condition
Dana-Farber scientists pinpoint a molecular cause of cachexia, a wasting of fat and muscle occurring in half of all cancer patients, and identify a protein that when blocked might prevent the condition.
National Institutes of Health

Contact: Teresa Herbert
Dana-Farber Cancer Institute

Public Release: 10-Jul-2014
International Journal of Clinical and Experimental Hypnosis
Men's hot flashes: Hypnotic relaxation may ease the discomfort men don't talk about
Men who experience hot flashes are unlikely to talk much about it, but they may find relief from their silent suffering if they are willing to try an unusual treatment, according to findings from a Baylor University case study.
National Institutes of Health

Contact: Terry Goodrich
Baylor University

Public Release: 10-Jul-2014
Biochemical Journal
Research reveals how key controller protein is switched on
New research has uncovered how a complex protein pivotal in the development of cancer, viral infection and autoimmune diseases is activated. The discovery answers a key question about one of the most widely-researched proteins in human biology, which has been the subject of tens of thousands of research papers and millions of pounds in research funding.
Wellcome Trust, Medical Research Council, AstraZeneca, Boehringer Ingelheim, and others

Contact: Alastair Stewart
Biochemical Society

Public Release: 10-Jul-2014
Cultured CTCs reveal genetic profile, potential drug susceptibility of breast cancer cells
A study in the July 11 issue of Science finds that circulating tumor cells captured with a microchip-based device developed at Massachusetts General Hospital can be cultured to establish cell lines for genetic analysis and drug testing and that those cell lines accurately reflect a tumor's genetic mutation over time and changing susceptibility to therapeutic drugs.
Johnson & Johnson, Stand Up to Cancer, Breast Cancer Research Foundation, National Institutes of Health, Howard Hughes Medical Institute

Contact: Katie Marquedant
Massachusetts General Hospital

Public Release: 10-Jul-2014
Clinical Cancer Research
New drug active against most aggressive type of lung cancer cells
Scientists from the Cancer Research UK Manchester Institute, based at The University of Manchester and part of the Manchester Cancer Research Centre, teamed up with experts at AstraZeneca, as part of a collaboration agreed in 2010, to test a drug -- known as AZD3965 -- on small cell lung cancer cells.

Contact: Alison Barbuti
University of Manchester

Public Release: 10-Jul-2014
USC stem cell researcher targets the 'seeds' of breast cancer metastasis
For breast cancer patients, the era of personalized medicine may be just around the corner, thanks to recent advances by USC Stem Cell researcher Min Yu and scientists at Massachusetts General Hospital and Harvard Medical School. In a July 11 study in Science, Yu and her colleagues report how they isolated breast cancer cells circulating through the blood streams of six patients.
Breast Cancer Research Foundation, Stand Up to Cancer, Wellcome Trust, National Foundation for Cancer Research, National Institutes of Health, NIH/National Institute of Biomedical Imaging and Bioengineering, Susan G. Komen for the Cure K

Contact: Cristy Lytal
University of Southern California - Health Sciences

Public Release: 10-Jul-2014
British Journal of Cancer
New therapeutic combination to slow resistant sarcomas
Researchers at sarcomas research group at the Bellvitge Biomedical Research Institute and the Catalan Institute of Oncology have been tested in 19 patients a new therapeutic combination to combat resistant sarcomas. The clinical trial results, which indicate that the new treatment could stabilize the growth of these tumors have been published this week in the British Journal of Cancer.

Contact: Arantxa Mena
IDIBELL-Bellvitge Biomedical Research Institute

Public Release: 9-Jul-2014
Dermatology Online Journal
Study of dermatology on YouTube shows new ways science reaches public
A University of Colorado Cancer Center study published in the Dermatology Online Journal shows that YouTube also allows researchers, journals, and health advocates to connect directly with the public on topics of skin cancer and prevention.

Contact: Garth Sundem
University of Colorado Denver

Public Release: 9-Jul-2014
Signal may send cancer's cellular factories into overdrive
A network of signals active in almost all types of cancer sends the protein factories in our cells into overdrive, and may help fuel a tumor's uncontrolled growth, new research suggests.
Biotechnology and Biological Sciences Research Council, Wellcome Trust

Contact: Graham Shaw
Biotechnology and Biological Sciences Research Council

Public Release: 9-Jul-2014
Wake-up call for more research into cell metabolism
More scientific research into the metabolism of stromal support cells and immune cells -- and the role of the metabolism of these cell types in the development of diseases -- could open new therapeutic avenues for diabetes, inflammatory conditions and cancer. That was the conclusion of a review article by scientists from VIB and KU Leuven in the leading journal Nature.

Contact: Peter Carmeleit
VIB (the Flanders Institute for Biotechnology)

Public Release: 9-Jul-2014
Study identifies novel genomic changes in the most common type of lung cancer
Researchers from The Cancer Genome Atlas Research Network have identified novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma, the most common subtype of lung cancer.
NIH/National Cancer Institute, NIH/National Human Genome Research Institute

Contact: Press Office
NIH/National Cancer Institute

Public Release: 9-Jul-2014
Lung cancer study hints at new treatments
Studying the most common type of lung cancer, researchers have uncovered mutations in a cell-signaling pathway that plays a role in forming tumors. The new knowledge may expand treatments for patients because drugs targeting some of these genetic changes already are available or are in clinical trials.
National Institutes of Health

Contact: Julia Evangelou Strait
Washington University School of Medicine

Public Release: 9-Jul-2014
Journal of Clinical Oncology
Sunshine vitamin ups bowel cancer survival odds, study finds
Bowel cancer patients with high levels of vitamin D in their blood are more likely to survive the disease, a University of Edinburgh study shows.
Cancer Research UK

Contact: Jen Middleton
University of Edinburgh

Public Release: 9-Jul-2014
Protein pushes breast cancer cells to metastasize
Using an innovative tool that captures heretofore hidden ways that cells are regulated, scientists at Rockefeller University have identified a protein that makes breast cancer cells more likely to metastasize. What's more, the protein appears to trigger cancer's spread in part by blocking two other proteins that are normally linked to neurodegeneration, a finding that suggests these two disease processes could have unexpected ties.
National Institutes of Health, US Department of Defense

Contact: Franklin Hoke
Rockefeller University

Public Release: 9-Jul-2014
Journal of the American College of Surgeons
Fox Chase researchers recommend updating the staging criteria for breast cancer diagnoses
New findings from Fox Chase Cancer Center paint a relatively optimistic picture of women's chances of surviving a subset of breast cancers that have spread to the chest wall or skin, but not beyond.

Contact: Diana Quattrone
Fox Chase Cancer Center

Public Release: 9-Jul-2014
Journal of Clinical Oncology
Depressed men with prostate cancer are diagnosed later stage, get less effective therapies
Depressed men with localized prostate cancer were more likely to be diagnosed with more aggressive prostate cancer, received less effective treatments and survived for shorter times than prostate cancer patients who were not depressed, a UCLA study has found.
Department of Defense Physician Training Award

Contact: Kim Irwin
University of California - Los Angeles Health Sciences

Public Release: 9-Jul-2014
New England Journal of Medicine
How antioxidants can accelerate cancers, and why they don't protect against them
Two distinguished cancer researchers have proposed why antioxidant supplements might not be working to reduce cancer development, and why they may actually do more harm than good.
Lustgarden Pancreatic Cancer Foundation

Contact: Peter Tarr
Cold Spring Harbor Laboratory

Public Release: 9-Jul-2014
Journal of Clinical Oncology
Vasectomy may increase risk of aggressive prostate cancer
Vasectomy was associated with a small increased risk of prostate cancer, and a stronger risk for advanced or lethal prostate cancer according to a new study from Harvard School of Public Health.
NIH/National Cancer Institute

Contact: Todd Datz
Harvard School of Public Health

Public Release: 9-Jul-2014
Nature Communications
CNIO scientists discover that pluripotency factor NANOG is also active in adult organisms
Scientists from the Spanish National Cancer Research Center (CNIO) have discovered that NANOG, an essential gene for embryonic stem cells, also regulates cell division in stratified epithelia in adult organisms. According to the conclusions of the study, published in the journal Nature Communications, this factor could also play a role in the formation of tumors derived from stratified epithelia of the esophagus and skin.

Contact: Nuria Noriega
Centro Nacional de Investigaciones Oncologicas (CNIO)

Public Release: 8-Jul-2014
Nature Genetics
Variations in key gene predict cancer patients' risk for radiation-induced toxicity
Key genetic variants may affect how cancer patients respond to radiation treatments, according to a study published this week in Nature Genetics.

Contact: David Slotnick
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 8-Jul-2014
Archives of Toxicology
Low doses of arsenic cause cancer in male mice
Mice exposed to low doses of arsenic in drinking water, similar to what some people might consume, developed lung cancer, researchers at the National Institutes of Health have found.
NIH/National Institute of Environmental Health Sciences

Contact: Robin Mackar
NIH/National Institute of Environmental Health Sciences

Public Release: 8-Jul-2014
Nature Communications
Brain tumor invasion along blood vessels may lead to new cancer treatments
Invading glioblastoma cells may hijack cerebral blood vessels during early stages of disease progression and damage the brain's protective barrier, a study in mice indicates. This finding could ultimately lead to new ways to bring about the death of the tumor, as therapies may be able to reach these deadly cells at an earlier time point than was previously thought possible.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Barbara McMakin
NIH/National Institute of Neurological Disorders and Stroke

Public Release: 8-Jul-2014
PLOS Medicine
NCI study finds extreme obesity may shorten life expectancy up to 14 years
Adults with extreme obesity have increased risks of dying at a young age from cancer and many other causes including heart disease, stroke, diabetes, and kidney and liver diseases, according to results of an analysis of data pooled from 20 large studies of people from three countries.
NIH/National Cancer Institute

Contact: NCI Press Officers
NIH/National Cancer Institute

Public Release: 8-Jul-2014
Gene mutation may lead to treatment for liver cancer
Two genetic mutations in liver cells may drive tumor formation in intrahepatic cholangiocarcinoma.

Contact: Lucia Lee
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 8-Jul-2014
Nursing Research
Harmful hookahs: Many young smokers aren't aware of the danger
Despite warnings from the Centers for Disease Control and Prevention that hookah smoking can be just as dangerous as cigarettes, many young adults believe that using the water pipes is not harmful to their health, according to a UCLA School of Nursing study.

Contact: Laura Perry
University of California - Los Angeles

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