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Showing releases 926-950 out of 1240.

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Public Release: 12-Aug-2014
Flexible sigmoidoscopy screening reduces colorectal cancer incidence, rate of death
Among about 100,000 study participants, screening with flexible sigmoidoscopy resulted in a reduced incidence and rate of death of colorectal cancer, compared to no screening, according to a study in the Aug. 13 issue of JAMA.

Contact: Øyvind Holme, M.D.
The JAMA Network Journals

Public Release: 12-Aug-2014
European Urology
Less radical procedures offer similar cancer control for kidney cancer patients
Needle-guided tumor destruction procedures offer near equivalent lengths of local cancer control compared to surgery for patients with small kidney cancer tumors, according to the results of a large study published in the journal European Urology. 'If validated, these data suggest that an update to clinical guidelines would be warranted,' says the study's lead author, R. Houston Thompson, M.D., a Mayo Clinic urologist.

Contact: Joe Dangor
Mayo Clinic

Public Release: 12-Aug-2014
Hijacking the brain's blood supply: Tumor discovery could aid treatment
Dangerous brain tumors hijack the brain's existing blood supply throughout their progression, by growing only within narrow potential spaces between and along the brain's thousands of small blood vessels, new research shows for the first time.
NIH/National Institute of Neurological Diseases and Stroke

Contact: Kara Gavin
University of Michigan Health System

Public Release: 12-Aug-2014
'Trojan horse' treatment could beat brain tumors
A 'Trojan horse' treatment for an aggressive form of brain cancer, which involves using tiny nanoparticles of gold to kill tumor cells, has been successfully tested by scientists. The ground-breaking technique could eventually be used to treat glioblastoma multiforme, which is the most common and aggressive brain tumor in adults, and notoriously difficult to treat.

Contact: Tom Kirk
University of Cambridge

Public Release: 12-Aug-2014
Journal of Cancer Survivorship
Beating childhood cancer does not make survivors healthier adults
Having survived cancer as a child does not necessarily have a ripple effect that makes people lead a healthier lifestyle once they grow up.

Contact: Alexander K. Brown
Springer Science+Business Media

Public Release: 12-Aug-2014
New analysis reveals tumor weaknesses
Epigenetic markers in cancer cells could improve patient treatment.
National Science Foundation, Burroughs Wellcome Fund, NIH/National Institute for Environmental Health Sciences, James H. Ferry Fund for Innovation

Contact: Andrew Carleen
Massachusetts Institute of Technology

Public Release: 11-Aug-2014
JAMA Internal Medicine
Bone drugs may not protect osteoporotic women from breast cancer
Osteoporosis drugs known as bisphosphonates may not protect women from breast cancer as had been thought, according to a new study led by researchers at UC San Francisco.

Contact: Laura Kurtzman
University of California - San Francisco

Public Release: 11-Aug-2014
Proceedings of the National Academy of Sciences
Scientists demonstrate long-sought drug candidate can halt tumor growth
Scientists at The Scripps Research Institute have disrupted the function of MYC, a cancer regulator thought to be 'undruggable.' The researchers found that a credit card-like molecule they developed somehow moves in and disrupts the critical interactions between MYC and its binding partner.
Pfizer Inc., NIH/National Cancer Institute, The Skaggs Institute for Chemical Biology, Austrian Science Fund

Contact: Mika Ono
Scripps Research Institute

Public Release: 11-Aug-2014
Cancer Epidemiology, Biomarkers & Prevention
Postmenopausal breast cancer risk decreases rapidly after starting reg. physical activity
Postmenopausal women who in the past four years had undertaken regular physical activity equivalent to at least four hours of walking per week had a lower risk for invasive breast cancer compared with women who exercised less during those four years, according to data published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
Institut National du Cancer, Fondation de France, Institut de Recherche en Santé Publique, Mutuelle Générale de l'Education Nationale, Institut de Cancérologie Gustave Roussy, Institut National de la Santé

Contact: Jeremy Moore
American Association for Cancer Research

Public Release: 11-Aug-2014
American Chemical Society 248th National Meeting & Exposition
Venom gets good buzz as potential cancer-fighter (video)
Bee, snake or scorpion venom could form the basis of a new generation of cancer-fighting drugs, scientists will report. They devised a method for targeting venom proteins specifically to malignant cells while sparing healthy ones, which reduces or eliminates side effects that the toxins would otherwise cause. Their study is part of the 248th National Meeting of the American Chemical Society. A brand-new video on the research is available at

Contact: Michael Bernstein
American Chemical Society

Public Release: 11-Aug-2014
JAMA Internal Medicine
Bisphosphonates for osteoporosis not associated with reduced breast cancer risk
An analysis of data from two randomized clinical trials finds that 3-4 years of treatment with bisphosphonates to improve bone density is not linked to reduced risk of invasive postmenopausal breast cancer.

Contact: Laura Kurtzman
The JAMA Network Journals

Public Release: 11-Aug-2014
Developmental Cell
How breast cancer usurps the powers of mammary stem cells
During pregnancy, certain hormones trigger specialized mammary stem cells to create milk-producing cells essential to lactation. Scientists at the University of California, San Diego School of Medicine and Moores Cancer Center have found that mammary stem cells associated with the pregnant mammary gland are related to stem cells found in breast cancer.
National Institutes of Health, California Breast Cancer Research Program

Contact: Yadira Galindo
University of California - San Diego

Public Release: 11-Aug-2014
Cancer Cell
Stanford researchers uncover cancer-causing mechanism behind powerful human oncogene
A protein present at high levels in more than half of all human cancers drives cell growth by blocking the expression of just a handful of genes involved in DNA packaging and cell death, according to a new study by researchers at the Stanford University School of Medicine.

Contact: Krista Conger
Stanford University Medical Center

Public Release: 11-Aug-2014
Journal of Experimental Medicine
Tackling liver injury
Researchers uncover a new drug that spurs liver regeneration after surgery.
National Institutes of Health, National Natural Science Foundation of China, Guangxi Natural Science Foundation, Science & Technology Planning Project of Guangxi Province, Science &Technology Planning Project of Guilin City

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 11-Aug-2014
Proceedings of the National Academy of Sciences
Novel drug action against solid tumors explained
Researchers at UC Davis, City of Hope, Taipai Medical University and National Health Research Institutes in Taiwan have discovered how a drug that deprives the cells of a key amino acid specifically kills cancer cells.

Contact: Carole Gan
University of California - Davis Health System

Public Release: 11-Aug-2014
ASU-Mayo researchers use calcium isotope analysis to predict myeloma progression
A team of researchers from Arizona State University and Mayo Clinic is showing how a staple of Earth science research can be used in biomedical settings to predict the course of disease. The researchers tested a new approach to detecting bone loss in cancer patients by using calcium isotope analysis to predict whether myeloma patients are at risk for developing bone lesions, a hallmark of the disease.

Contact: Skip Derra
Arizona State University

Public Release: 11-Aug-2014
Focal blood-brain-barrier disruption with high-frequency pulsed electric fields
Novel method uses bursts of nanosecond duration electric pulses to open the blood-brain-barrier as a potential therapy for brain cancer and neurological disorders.
National Science Foundation, Golfers Against Cancer, Center for Biomolecular Imaging in the Wake Forest School of Medicine

Contact: Philly Lim
World Scientific

Public Release: 11-Aug-2014
US lung cancer rates vary by subtype, sex, race/ethnicity, and age
A new analysis confirms that US lung cancer rates are declining overall, but it also uncovers previously unrecognized trends related to cancer subtype, sex, race/ethnicity, and age.

Contact: Evelyn Martinez

Public Release: 11-Aug-2014
Nature Chemistry
Synthetic molecule makes cancer self-destruct
Researchers from The University of Texas at Austin and five other institutions have created a molecule that can cause cancer cells to self-destruct by ferrying sodium and chloride ions into the cancer cells. These synthetic ion transporters, described this week in the journal Nature Chemistry, confirm a two-decades-old hypothesis that could point the way to new anticancer drugs while also benefitting patients with cystic fibrosis.
National Creative Research Initiative, Office of Basic Energy Sciences, Chemical Biology Research Center

Contact: Steve Franklin
University of Texas at Austin

Public Release: 11-Aug-2014
Cancer Cell
CRI scientists pinpoint gene likely to promote childhood cancers
Researchers at the Children's Medical Center Research Institute at UT Southwestern have identified a gene that contributes to the development of several childhood cancers, in a study conducted with mice designed to model the cancers.

Contact: Randy Sachs
UT Southwestern Medical Center

Public Release: 11-Aug-2014
Proceedings of the National Academy of Sciences
Aberrant mTOR signaling impairs whole body physiology
The protein mTOR is a central controller of growth and metabolism. Deregulation of mTOR signaling increases the risk of developing metabolic diseases such as diabetes, obesity and cancer. In the current issue of the journal Proceedings of the National Academy of Sciences, researchers from the Biozentrum of the University of Basel describe how aberrant mTOR signaling in the liver not only affects hepatic metabolism but also whole body physiology.

Contact: Olivia Poisson
University of Basel

Public Release: 11-Aug-2014
Cancer Cell
Malaria medicine chloroquine inhibits tumor growth and metastases
A recent study by investigators at VIB and KU Leuven has demonstrated that chloroquine also normalizes the abnormal blood vessels in tumors. This blood vessel normalization results in an increased barrier function on the one hand -- thereby blocking cancer cell dissemination and metastasis -- and in enhanced tumor perfusion on the other hand, which increases the response of the tumor to chemotherapy.

Contact: Sooike Stoops
VIB (the Flanders Institute for Biotechnology)

Public Release: 10-Aug-2014
Scientists unlock key to blood vessel formation
Scientists from the University of Leeds have discovered a gene that plays a vital role in blood vessel formation, research which adds to our knowledge of how early life develops.
British Heart Foundation, Wellcome Trust, Medical Research Council

Contact: Ben Jones
University of Leeds

Public Release: 8-Aug-2014
Journal of Virology
Editing HPV's genes to kill cervical cancer cells
Using the genome editing tool known as CRISPR, Duke University researchers were able to selectively silence two genes in human papilloma virus that are responsible for the growth and survival of cervical carcinoma cells. After silencing the two HPV genes, the cancer cell's normal self-destruct machinery went into action.
National Institutes of Health

Contact: Karl Bates
Duke University

Public Release: 7-Aug-2014
Nature Cell Biology, Cell Cycle
A*Star scientists make breakthroughs in ovarian cancer research
Scientists at A*STAR's Institute of Medical Biology and the Bioinformatics Institute have found new clues to early detection and personalised treatment of ovarian cancer, currently one of the most difficult cancers to diagnose early due to the lack of symptoms that are unique to the illness.
Agency for Science, Technology and Research (A*STAR)

Contact: Vanessa Loh
Biomedical Sciences Institutes (BMSI)

Showing releases 926-950 out of 1240.

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