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Showing releases 951-975 out of 1182.

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Public Release: 5-Sep-2014
Nature Communications
UT Southwestern researchers find new gene mutations for Wilms Tumor
Researchers at UT Southwestern Medical Center and the Gill Center for Cancer and Blood Disorders at Children's Medical Center, Dallas, have made significant progress in defining new genetic causes of Wilms tumor, a type of kidney cancer found only in children.

Contact: Lori Sundeen Soderbergh
UT Southwestern Medical Center

Public Release: 5-Sep-2014
Cancer Epidemiology, Biomarkers & Prevention
Research finds no association between wearing a bra and breast cancer
A population-based case-control study found no association between bra wearing and increased breast cancer risk among postmenopausal women, according to research published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
NIH/National Cancer Institute

Contact: Jeremy Moore
American Association for Cancer Research

Public Release: 5-Sep-2014
Combination microRNA therapy shown to suppress non-small-cell lung cancer
New findings show that a combination of two microRNAs suppressed tumor growth in an an animal model of non-small-cell lung cancer.
American Cancer Society, National Institutes of Health, Cancer Prevention & Research Institute of Texas

Contact: Bonnie Prescott
Beth Israel Deaconess Medical Center

Public Release: 5-Sep-2014
Clinical Cancer Research
New blood test could offer more tailored treatment of ovarian cancer
Researchers from the University of Manchester and The Christie NHS Foundation Trust -- both part of Manchester Cancer Research Centre -- say the test could be developed and used in hospitals within the next few years.

Contact: Alison Barbuti
University of Manchester

Public Release: 4-Sep-2014
New England Journal of Medicine
Phase III FIRST (MM-020/IFM 07-01) trial of REVLIMID (lenalidomide) plus dexamethasone in newly diagnosed multiple myeloma patients who are not candidates for stem cell transplant published in New England Journal of Medicine
The study met the primary endpoint as a significant progression-free survival benefit was seen for patients treated with continuous REVLIMID plus dexamethasone compared with those treated with a standard of care.
Intergroupe Francophone du Myélome, Celgene

Contact: Celgene Corporation
Celgene Corporation

Public Release: 4-Sep-2014
Breast Cancer Symposium 2014
Breast radiation trial provides more convenience, better compliance, lowered cost
An experimental regimen of once-weekly breast irradiation following lumpectomy provides more convenience to patients at a lower cost, results in better completion rates of prescribed radiation treatment, and produces cosmetic outcomes comparable to the current standard of daily radiation.

Contact: Jill Scoggins
University of Louisville

Public Release: 4-Sep-2014
Journal of the National Cancer Institute
Soy supplementation adversely effects expression of breast cancer-related genes
Soy supplementation alters expression of genes associated with breast cancer, raising concerns that soy could have adverse effects in breast cancer, according to a new study published Sept. 4 in the JNCI: Journal of the National Cancer Institute.

Contact: Zachary Rathner
Oxford University Press USA

Public Release: 4-Sep-2014
Breast Cancer Symposium 2014
Disparities persist in early-stage breast cancer treatment, MD Anderson study finds
Despite its acceptance as standard of care for early stage breast cancer almost 25 years ago, barriers still exist that preclude patients from receiving breast conserving therapy, with some still opting for a mastectomy, according to research from The University of Texas MD Anderson Cancer Center.

Contact: Laura Sussman
University of Texas M. D. Anderson Cancer Center

Public Release: 4-Sep-2014
The newest precision medicine tool: Prostate cancer organoids
Research led by investigators at Memorial Sloan Kettering Cancer Center has shown for the first time that organoids derived from human prostate cancer tumors can be grown in the laboratory, giving researchers an exciting new tool to test cancer drugs and personalize cancer treatment.
Stand Up To Cancer-Prostate Cancer Foundation Prostate Dream Team Translational Cancer Research Grant, National Institutes of Health, US Department of Defense, Movember Foundation, Geoffrey Beene Cancer Research Center

Contact: Andrea Baird
Memorial Sloan Kettering Cancer Center

Public Release: 4-Sep-2014
Cell Reports
Study identifies gene network behind untreatable leukemia and possible treatment target
Researchers have identified a genetic/molecular network that fuels a high-risk and aggressive form of acute myeloid leukemia and its precursor disease myelodysplastic syndrome -- providing a possible therapeutic strategy for an essentially untreatable form of the blood cancer. Scientists from the Cancer and Blood Diseases Institute at Cincinnati Children's Hospital Medical Center report their results in a study posted online Sept. 4 by Cell Reports.
Cincinnati Children's Hospital Research Foundation, American Society of Hematology, National Institutes of Health, Department of Defense, NIH/National Institute of Diabetes, Digestive and Kidney Diseases

Contact: Nick Miller
Cincinnati Children's Hospital Medical Center

Public Release: 4-Sep-2014
Nature Biotechnology
Most accurate measures of gene expression
RNA-sequencing data analysis method BitSeq developed by Academy Research Fellow Antti Honkela's, Univeristy of Helsinki, research group and University of Manchester researchers has been found to be the most accurate gene transcript expression estimation method in a large international assessment. The method is based on probabilistic modelling which can capture the uncertainty related to the measurements.

Contact: Antti Honkela
University of Helsinki

Public Release: 4-Sep-2014
SingHealth Duke-NUS Scientific Congress 2014
Study reveals breast surgery as a definitive and safe treatment for elderly patients
A study conducted by National Cancer Centre Singapore has shown that age per se is not a contraindication to breast cancer surgery, and such surgeries may be safely performed for women aged 80 years and above. Led by Dr. Ong Kong Wee, Senior Consultant in the Division of Surgical Oncology, the team consists of Dr. Veronique Tan, Consultant, and Dr. Lee Chee Meng, Resident Doctor. The study explores the safety of breast cancer surgery in women aged 80 years and above.

Contact: Edwin Yong

Public Release: 4-Sep-2014
Breast Cancer Symposium 2014
Breast conserving therapy shows survival benefit compared to mastectomy in early-stage patients
When factoring in what is now known about breast cancer biology and heterogeneity, breast conserving therapy may offer a greater survival benefit over mastectomy to women with early stage, hormone-receptor positive disease, according to research from The University of Texas MD Anderson Cancer Center.

Contact: Laura Sussman
University of Texas M. D. Anderson Cancer Center

Public Release: 4-Sep-2014
Team identifies important regulators of immune cell response
In a collaborative study, scientists from the Florida campus of The Scripps Research Institute and the La Jolla Institute for Allergy and Immunology have developed a more effective method to determine how immune cells called T cells differentiate into specialized types of cells that help eradicate infected cells and assist other immune cells during infection.
National Institutes of Health, Frenchman's Creek Women for Cancer Research

Contact: Eric Sauter
Scripps Research Institute

Public Release: 4-Sep-2014
International Conference of the American Thoracic Society
A minimally invasive, high-performance intervention for staging lung cancer
Endoscopic biopsy of lymph nodes between the two lungs (mediastinum) is a sensitive and accurate technique that can replace mediastinal surgery for staging lung cancer in patients with potentially resectable tumours.
Canadian Foundation for Innovation, Society of University Surgeons, Fonds de recherche en santé du Québec, Thoracic Surgery Research Foundation of Montreal

Contact: Benjamin Augereau
University of Montreal

Public Release: 4-Sep-2014
Nature Communications
Avian influenza virus isolated in harbor seals poses a threat to humans
A study led by St. Jude Children's Research Hospital scientists found the avian influenza A H3N8 virus that killed harbor seals along the New England coast can spread through respiratory droplets and poses a threat to humans. The research appears in the current issue of the scientific journal Nature Communications.
NIH/National Institutes of Allergy and Infectious Diseases US Geological Survey, American Lebanese Syrian Associated Charities

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Public Release: 4-Sep-2014
Breast Cancer Symposium 2014
2014 Breast Cancer Symposium highlights research advances in prevention, screening, therapy
Five studies from the 2014 Breast Cancer Symposium were highlighted today in an embargoed presscast for reporters. Presentations focused on new studies exploring preventive mastectomy, compliance with recommended screening mammography, and risk of recurrence after pre-surgery therapy for breast cancer. The Symposium will take place Sept. 4-6, 2014, at the San Francisco Marriott Marquis in San Francisco, CA.

Contact: Kate Blackburn
American Society of Clinical Oncology

Public Release: 3-Sep-2014
New England Journal of Medicine
Blood test for 'nicked' protein predicts prostate cancer treatment response
Prostate cancer patients whose tumors contain a shortened protein called AR-V7, which can be detected in the blood, are less likely to respond to two widely used drugs for metastatic prostate cancer, according to results of a study led by researchers at the Johns Hopkins Kimmel Cancer Center.
Prostate Cancer Foundation, US Department of Defense, NIH/National Cancer Institute

Contact: Vanessa Wasta
Johns Hopkins Medicine

Public Release: 3-Sep-2014
JAMA Dermatology
Airline pilots, cabin crews have higher incidence of melanoma
Airline pilots and cabin crews appear to have twice the incidence of melanoma as the general population.

Contact: Elizabeth Fernandez
The JAMA Network Journals

Public Release: 3-Sep-2014
Nature Communications
CNIO experts discover the genomic origin of telomere protectors
A study led by Centro Nacional de Investigaciones Oncologicas researchers has discovered that telomeric repeat-containing RNA do not originate in all telomeres that protect the 20 murine chromosomes, but do exclusively in chromosome 18 and, to a lesser extent, in chromosome 9. This peculiarity sets the stage for future genetic manipulation in mice with the aim of researching the in vivo role of these molecules in telomere biology and in illness. The results have been published in Nature Communications.
Ministry of Economy and Competitiveness, Community of Madrid, European Union, Lilly Foundation, Fundación Botín, AXA Research Fund

Contact: Nuria Noriega
Centro Nacional de Investigaciones Oncologicas (CNIO)

Public Release: 3-Sep-2014
PLOS Pathogens
Leaky gut -- A source of non-AIDS complications in HIV-positive patients
Human immunodeficiency virus infection is no longer a fatal condition, thanks to newer medications inhibiting the retrovirus, but a phenomenon has surfaced among these patients -- non-AIDS complications. Scientists at Case Western Reserve University School of Medicine have resolved the mystery with their discovery of the leaky gut as the offender. Bacterial products seep out of the colon, trigger inflammation and set off the processes of cardiovascular, neurodegenerative, chronic kidney and metabolic diseases, and cancer.
National Institutes of Health

Contact: Jeannette Spalding
Case Western Reserve University

Public Release: 3-Sep-2014
Innovative algorithm spots interactions lethal to cancer
An ideal anti-cancer treatment -- one that's immediately lethal to cancer cells, harmless to healthy cells, and resistant to cancer's relapse -- is still a dream. New research from Tel Aviv University takes a step closer to the realization of that dream with an innovative computer algorithm that spots cancer-busting 'genetic partners' whose interactions are lethal to cancer cells.

Contact: George Hunka
American Friends of Tel Aviv University

Public Release: 3-Sep-2014
ACS Nano
Handheld scanner could make brain tumor removal more complete, reducing recurrence
Cancerous brain tumors are notorious for growing back despite surgical attempts to remove them -- and for leading to a dire prognosis for patients. But scientists are developing a new way to try to root out malignant cells during surgery so fewer or none get left behind to form new tumors. The method, reported in the journal ACS Nano, could someday vastly improve the outlook for patients.

Contact: Michael Bernstein
American Chemical Society

Public Release: 3-Sep-2014
Journal of the National Cancer Institute
Genetic 'hotspot' linked to endometrial cancer aggressiveness
Scientists at The University of Texas MD Anderson Cancer Center in Houston have identified genetic mutations in endometrioid endometrial carcinoma, the most common form of this cancer of the uterine lining.

Contact: Ron Gilmore
University of Texas M. D. Anderson Cancer Center

Public Release: 2-Sep-2014
Proceedings of the National Academy of Sciences
Enzyme controlling metastasis of breast cancer identified
Researchers at the University of California, San Diego School of Medicine have identified an enzyme that controls the spread of breast cancer. The findings, reported in the current issue of PNAS, offer hope for the leading cause of breast cancer mortality worldwide. An estimated 40,000 women in America will die of breast cancer in 2014, according to the American Cancer Society.
Susan G. Komen for the Cure, National Institutes of Health, Pedal the Cause San Diego

Contact: Scott LaFee
University of California - San Diego

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