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Public Release: 9-Jun-2014
Cancer
Most breast cancer patients may not be getting enough exercise
Physical activity after breast cancer diagnosis has been linked with prolonged survival and improved quality of life, but most participants in a large breast cancer study did not meet national physical activity guidelines after they were diagnosed.

Contact: Evelyn Martinez
sciencenewsroom@wiley.com
201-748-6358
Wiley

Public Release: 9-Jun-2014
Journal of Clinical Investigation
Resistance to lung cancer targeted therapy can be reversed, study suggests
Up to 40 percent of lung cancer patients do not respond to a targeted therapy designed to block tumor growth -- a puzzling clinical setback that researchers have long tried to solve. Now, scientists have discovered why that intrinsic resistance occurs -- and they pinpoint a drug they say could potentially reverse it.

Contact: Karen Teber
km463@georgetown.edu
Georgetown University Medical Center

Public Release: 9-Jun-2014
Annals of Internal Medicine
News from Annals of Internal Medicine tip sheet -- June 10, 2014
The June 10 issue of Annals of Internal Medicine contains articles titled 'Increase screening rates to prevent cervical cancer, experts suggest' and 'Experts explain merits and shortcomings of Medicare data release.'

Contact: Megan Hanks
mhanks@acponline.org
215-351-2656
American College of Physicians

Public Release: 9-Jun-2014
2014 SNMMI Annual Meeting
Molecular imaging finds novel way to knock down breast cancer
For years researchers have been developing molecular imaging techniques that visualize hormonally active breast cancer cells -- specifically those testing positive for human epidermal growth factor receptor 2. A recent innovation in breast cancer biomarkers seeks the HER3 receptor instead, which could mean more comprehensive breast cancer imaging and potential treatments, say experts presenting data during the Society of Nuclear Medicine and Molecular Imaging's 2014 Annual Meeting.

Contact: Kimberly Brown
kbrown@snmmi.org
703-652-6773
Society of Nuclear Medicine

Public Release: 9-Jun-2014
Nature Communications
UNC researchers pinpoint new role for enzyme in DNA repair, kidney cancer
Twelve years ago, UNC School of Medicine researcher Brian Strahl, PhD, found that a protein called Set2 plays a role in how yeast genes are expressed -- specifically how DNA gets transcribed into messenger RNA. Now his lab has found that Set2 is also a major player in DNA repair, a complicated and crucial process that can lead to the development of cancer cells if the repair goes wrong.
National Institutes of Health

Contact: Mark Derewicz
mark.derewicz@unchealth.unc.edu
919-923-0959
University of North Carolina Health Care

Public Release: 9-Jun-2014
Annals of Internal Medicine
What's the best test for cervical cancer? Pap, HPV or both?
Should US women be screened for cervical cancer with Pap tests, HPV tests or both? According to researchers from Boston University School of Medicine and Boston Medical Center while the merits of screening tests and screening intervals warrant further discussion, they firmly believe that increasing the number of women who participate in cancer screenings and ensuring that women are not lost to follow-up with lengthened screening intervals is more important than the choice of test to decrease rates of cervical cancer.

Contact: Gina DiGravio
gina.digravio@bmc.org
617-638-8480
Boston University Medical Center

Public Release: 9-Jun-2014
2014 SNMMI Annual Meeting
A few circulating cancer cells could cue risk of metastases
A simple noninvasive blood test matched with state-of-the-art molecular imaging of individual cells could help oncologists understand their patients' chances of survival, say researchers at the Society of Nuclear Medicine and Molecular Imaging's 2014 Annual Meeting.

Contact: Kimberly Brown
kbrown@snmmi.org
703-652-6773
Society of Nuclear Medicine

Public Release: 9-Jun-2014
2014 SNMMI Annual Meeting
Enzyme-inhibition could revolutionize molecular imaging
The prominent role a single enzyme plays in cancer imaging has eluded researchers for years, but not anymore. This discovery could pave new avenues in nuclear medicine. The enzyme, called neutral endopeptidase, has a way of breaking down most radiopeptide imaging agents in the body. Researchers have developed an elegant new concept that improves molecular imaging, according to study results presented during the Society of Nuclear Medicine and Molecular Imaging's 2014 Annual Meeting.

Contact: Kimberly Brown
kbrown@snmmi.org
703-652-6773
Society of Nuclear Medicine

Public Release: 9-Jun-2014
2014 SNMMI Annual Meeting
Radioluminescence tells the story of single cells
With a new molecular imaging system powerful enough to peer down to 20-micrometer resolution, researchers can now use radioluminescence to examine the characteristics of single, unconnected cells. The result is a fascinating picture of diversity among cells previously assumed to behave the same, revealed researchers at the Society of Nuclear Medicine and Molecular Imaging's 2014 Annual Meeting.

Contact: Kimberly Brown
kbrown@snmmi.org
703-652-6773
Society of Nuclear Medicine

Public Release: 9-Jun-2014
Journal of Experimental Medicine
Combination therapy may help patients with follicular lymphoma
Follicular lymphoma is an incurable form of non-Hodgkin lymphoma that is diagnosed each year in 120,000 people worldwide. Researchers show that a high-risk group of patients with the disease could benefit from a novel drug combination.
NIH/National Cancer Institute, American Cancer Society, Leukemia Research Foundation, and others

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press

Public Release: 9-Jun-2014
2014 SNMMI Annual Meeting
Chemo-radionuclide therapy halts neuroendocrine cancer
Advanced cancer of the neuroendocrine system can lead to dismal prognoses, but a novel therapy is packing a punch by uniting powerful radionuclide treatment and chemotherapy drugs, revealed researchers at the Society of Nuclear Medicine and Molecular Imaging's 2014 Annual Meeting.

Contact: Kimberly Brown
kbrown@snmmi.org
703-652-6773
Society of Nuclear Medicine

Public Release: 8-Jun-2014
Nature Chemical Biology
New molecule enables quick drug monitoring
Scientists at EPFL have invented a molecule that can easily and quickly show how much drug is in a patient's system. The molecule, now the basis of a start-up company, is expected to enable point-of-care therapeutic drug monitoring.
École polytechnique fédérale de Lausanne, Swiss National Science Foundation, National Centre of Competence in Research Chemical Biology, Defense Threat Reduction

Contact: Nik Papageorgiou
n.papageorgiou@epfl.ch
41-216-932-105
Ecole Polytechnique Fédérale de Lausanne

Public Release: 8-Jun-2014
Nature Genetics
Longer telomeres linked to risk of brain cancer
New genomic research led by UC San Francisco scientists reveals that two common gene variants that lead to longer telomeres, the caps on chromosome ends thought by many scientists to confer health by protecting cells from aging, also significantly increase the risk of developing the deadly brain cancers known as gliomas.
National Institutes of Health, National Brain Tumor Foundation, University of California, San Francisco

Contact: Peter Farley
peter.farley@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 8-Jun-2014
Nature Materials
Targeting tumors using silver nanoparticles
Scientists at UC Santa Barbara have designed a nanoparticle that has a couple of unique -- and important -- properties. Spherical in shape and silver in composition, it is encased in a shell coated with a peptide that enables it to target tumor cells. What's more, the shell is etchable so those nanoparticles that don't hit their target can be broken down and eliminated. The research findings appear today in the journal Nature Materials.

Contact: Julie Cohen
julie.cohen@ucsb.edu
805-893-7220
University of California - Santa Barbara

Public Release: 8-Jun-2014
Health Affairs
Health Affairs asks: Where can we find savings in health care?
The June issue of Health Affairs features various approaches to cost savings in the US health care system, and several other articles that may be of interest to the global community.

Contact: Sue Ducat
sducat@projecthope.org
301-841-9962
Health Affairs

Public Release: 6-Jun-2014
Journal of Molecular Diagnostics
Biomarkers accurately distinguish mesothelioma from non-cancerous tissue
Scientists have identified four biomarkers that may help resolve the difficult differential diagnosis between malignant pleural mesothelioma (MPM) and non-cancerous pleural tissue with reactive mesothelial proliferations. This is a frequent differential diagnostic problem in pleural biopsy samples taken from patients with clinical suspicion of MPM. The ability to make more accurate diagnoses earlier may facilitate improved patient outcomes. This new study appears in the Journal of Molecular Diagnostics.

Contact: Eileen Leahy
jmdmedia@elsevier.com
732-238-3628
Elsevier Health Sciences

Public Release: 6-Jun-2014
Endocrine-Related Cancer
Prostate cancer biomarkers identified in seminal fluid
Improved diagnosis and management of one of the most common cancers in men -- prostate cancer -- could result from research at the University of Adelaide, which has discovered that seminal fluid contains biomarkers for the disease.
Prostate Cancer Foundation

Contact: Dr. Luke Selth
luke.selth@adelaide.edu.au
61-882-223-618
University of Adelaide

Public Release: 6-Jun-2014
Journal of Virology
Herpesviruses undercover
Pathogens entering our body only remain unnoticed for a short period. Within minutes our immune cells detect the invader and trigger an immune response. However, some viruses have developed strategies to avoid detection and elimination by our immune system. Researchers from the Helmholtz Centre for Infection Research in Braunschweig have now been able to show how the herpesviruses achieve this.

Contact: Rebecca Winkels
rebecca.winkels@helmholtz-hzi.de
49-531-618-11403
Helmholtz Centre for Infection Research

Public Release: 6-Jun-2014
Clinical Gastroenterology and Hepatology
Probiotics prevent deadly complications of liver disease
Probiotics are effective in preventing hepatic encephalopathy in patients with cirrhosis of the liver, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

Contact: Rachel Steigerwald
media@gastro.org
301-272-1603
American Gastroenterological Association

Public Release: 6-Jun-2014
Science
Scientists reveal details of calcium 'safety-valve' in cells
The New York Consortium on Membrane Protein Structure used X-rays at Brookhaven Lab's National Synchrotron Light Source to decipher the atomic level structure of a protein that regulates the level of calcium in cells, providing clues about a key signaling agent that can trigger programmed cell death and potentially leading to new anticancer drug targets.
National Institutes of Health, US Department of Energy

Contact: Karen McNulty Walsh
kmcnulty@bnl.gov
631-344-8350
DOE/Brookhaven National Laboratory

Public Release: 6-Jun-2014
Gastrointestinal Endoscopy
Endoscope with an oxygen sensor detects pancreatic cancer
An optical blood oxygen sensor attached to an endoscope is able to identify pancreatic cancer in patients via a simple lendoscopic procedure, according to researchers at Mayo Clinic in Florida.
National Institutes of Health, NIH/National Cancer Institute, Mayo Clinic Foundation for Medical Education & Research

Contact: Kevin Punsky
punsky.kevin@mayo.edu
904-953-0746
Mayo Clinic

Public Release: 5-Jun-2014
Analytical Chemistry
Research could lead to new cancer assay, aid both dogs and humans
Veterinary researchers have identified a unique group of proteins that indicate the presence of transitional cell carcinoma -- the most common cause of bladder cancer -- and may lead to a new assay which could better diagnose this disease in both dogs and humans.
NIH/National Insitutes of Environmental Health Sciences

Contact: Shay Bracha
shay.bracha@oregonstate.edu
541-737-4844
Oregon State University

Public Release: 5-Jun-2014
Science
MAD: Scientists shed light on braking mechanisms in cellular signaling
A team of researchers studying a flowering plant has zeroed in on the way cells manage external signals about prevailing conditions, a capability that is essential for cells to survive in a fluctuating environment.

Contact: Zhiyong Wang
zwang@carnegiescience.edu
650-739-4205
Carnegie Institution

Public Release: 5-Jun-2014
Cancer Discovery
Seemingly invincible cancers stem cells reveal a weakness
Metastatic cancer cells, which can migrate from primary tumors to seed new malignancies, have thus far been resistant to the current arsenal of anticancer drugs. Now, however, researchers at Whitehead Institute have identified a critical weakness that actually exploits one of these cells' apparent strengths -- their ability to move and invade tissues. Their research could inform novel approaches to screening tumors for personalized therapy or to drugs that specifically target these cells.
Richard and Susan Smith Family Foundation, Breast Cancer Alliance

Contact: Nicole Giese Rura
rura@wi.mit.edu
617-258-6851
Whitehead Institute for Biomedical Research

Public Release: 5-Jun-2014
Structure
Scientists find new targets that could increase effectiveness of breast cancer treatments
Scientists from the Florida campus of the Scripps Research Institute have found new targets for potential intervention in breast cancer. These new targets could eventually increase effectiveness and reduce the undesirable side effects associated with current treatments.
National Institutes of Health, NIH/National Cancer Institute

Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute

Showing releases 951-975 out of 1260.

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