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Showing releases 951-975 out of 1212.

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Public Release: 15-Mar-2013
28th Annual EAU Congress
New study: Incidence and mortality of PCa after termination of PSA-based screening
Men who participate in biennial PSA based screening have a lower risk of being diagnosed as well as dying from prostate cancer up to 9 years after their last PSA test, according to the results of a new study to be presented at the 28th Annual EAU Congress in Milan.

Contact: Ivanka Moerkerken
i.moerkerken@uroweb.org
31-026-389-0680
European Association of Urology

Public Release: 15-Mar-2013
Journal of Clinical Investigation
Sorting out fertility after childhood cancer
In this issue of the Journal of Clinical Investigation, Orwig and colleagues report the development of a multi-parameter sorting approach to separate spermatagonial stem cells from cancerous cells.
National Institutes of Health, Richard King Mellon Foundation, Magee-Womens Research Institute

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 15-Mar-2013
Journal of Clinical Investigation
JCI early table of contents for Mar. 15, 2013
The following release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, Mar. 15, 2013, in the JCI: Cytoskeletal dysregulation underlies Buruli ulcer formation; Sorting out fertility after childhood cancer; and many more.

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 15-Mar-2013
28th Annual EAU Congress
Japanese P2 study shows potential of combined vaccine and steroid drug in castration-resistant PCa
Multi-peptide vaccination therapy combined with the low-dose steroid drug dexamethasone shows promise in treating chemotherapy-naive castration resistant prostate cancer patients.

Contact: Ivanka Moerkerken
i.moerkerken@uroweb.org
31-026-389-0680
European Association of Urology

Public Release: 15-Mar-2013
28th Annual EAU Congress
Surgery is superior to radiotherapy in men with localized PCa, says prize-winning Swedish study
Surgery offers better survival benefit for men with localized prostate cancer, according to a large observational study, conducted by a group of researchers in Sweden and the Netherlands.

Contact: Ivanka Moerkerken
i.moerkerken@uroweb.org
31-026-389-0680
European Association of Urology

Public Release: 15-Mar-2013
28th Annual EAU Congress
Stem cells transplantation technique has high potential as a novel therapeutic strategy for ED
Transplantation of mesenchymal stem cells cultivated on the surface of nanofibrous meshes could be a novel therapeutic strategy against post-prostatectomy erectile dysfunction, conclude the authors of a study which is to be presented at the 28th Annual EAU Congress later this week.

Contact: Ivanka Moerkerken
i.moerkerken@uroweb.org
31-026-389-0680
European Association of Urology

Public Release: 15-Mar-2013
28th Annual EAU Congress
PCa markers improve predictive performance of existing clinical variables
A genetic score based on PCa risk-associated single nucleotide polymorphisms is an independent predictor of prostate biopsy outcomes, suggest the results of a new study conducted by a group from the Department of Urology Huashan Hospital, Fudan University in Shanghai, China.

Contact: Ivanka Moerkerken
i.moerkerken@uroweb.org
31-026-389-0680
European Association of Urology

Public Release: 15-Mar-2013
28th Annual EAU Congress
Study shows additional role for abiraterone in blocking tumor growth in CRPC
As part of an EU-supported IMI-PREDECT consortium, a Dutch study showed that anti-androgenic properties of the drug abiraterone may provide an additional mechanism of action in blocking tumor growth of castration resistant prostate cancer.
IMI-PREDECT Consortium

Contact: Ivanka Moerkerken
i.moerkerken@uroweb.org
31-026-389-0680
European Association of Urology

Public Release: 14-Mar-2013
PLOS ONE
New cancer diagnostic technique debuts
Cancer cells break down sugars and produce the metabolic acid lactate at a much higher rate than normal cells. This phenomenon provides a telltale sign that cancer is present, via diagnostics such as PET scans, and possibly offers an avenue for novel cancer therapies. Now a team of Chilean researchers and Carnegie's Wolf Frommer have devised a molecular sensor that can detect levels of lactate in individual cells in real time.
National Institutes of Health, Chilean Government, Carnegie

Contact: Wolf Frommer
wfrommer@carnegiescience.edu
650-739-4208
Carnegie Institution

Public Release: 14-Mar-2013
Journal of the National Cancer Institute
High-fat dairy products linked to poorer breast cancer survival
Patients who consume high-fat dairy products following breast cancer diagnosis increase their chances of dying from the disease years later, according to a study by Kaiser Permanente researchers.
NIH/National Cancer Institute

Contact: Vincent Staupe
vstaupe@golinharris.com
415-318-4386
Kaiser Permanente

Public Release: 14-Mar-2013
Journal of Neuro-Ophthalmology
Brain stent offers alternative to shunt for fixing potentially blinding vein narrowing
A team of interventional neuroradiologists and neurosurgeons at Johns Hopkins reports wide success with a new procedure to treat pseudotumor cerebri, a rare but potentially blinding condition marked by excessive pressure inside the skull, caused by a dangerous narrowing of a vein located at the base of the brain.

Contact: David March
dmarch1@jhmi.edu
410-955-1534
Johns Hopkins Medicine

Public Release: 14-Mar-2013
BJU International
Smoking linked with worse urothelial cancer prognosis in patients, especially women
Smoking significantly increases individuals' risk of developing serious forms of urothelial carcinoma and a higher likelihood of dying from the disease, particularly for women. That is the conclusion of a recent study published in BJU International. While the biological mechanisms underlying this gender difference are unknown, the findings indicate that clinicians and society in general should focus on smoking prevention and cessation to safeguard against deadly cancers of the bladder, ureters, and renal pelvis, especially in females.

Contact: Amy Molnar
sciencenewsroom@wiley.com
Wiley

Public Release: 14-Mar-2013
Biomedical Optics Express
Intense terahertz pulses cause DNA damage but also induce DNA repair
Terahertz radiation, a slice of the electromagnetic spectrum that occupies the middle ground between microwaves and infrared light, is rapidly finding important uses in medical diagnostics, security, and scientific research. As scientists and engineers find evermore practical uses for this form of radiation, questions persist about its potential human health risks.

Contact: Angela Stark
astark@osa.org
202-416-1443
The Optical Society

Public Release: 14-Mar-2013
Human Vaccines & Immunotherapeutics
HPV vaccine trends point to failures in patient education, vaccine programs
Completion rates for the human papillomavirus vaccine series across both genders continue to remain alarmingly low nearly seven years after its introduction, suggesting that better patient education and increased public vaccine financing programs are needed, according to new research from the University of Texas Medical Branch.
NIH/National Institute of Child Health and Human Development

Contact: Lauren Whisenant
lauren.whisenant@gabbe.com
832-723-2236
University of Texas Medical Branch at Galveston

Public Release: 14-Mar-2013
Science Signaling
Study shows how vitamin E can help prevent cancer
Researchers have identified an elusive anti-cancer property of vitamin E that has long been presumed to exist, but difficult to find.
National Institutes of Health

Contact: Ching-Shih Chen
chen@pharmacy.ohio-state.edu
614-688-4008
Ohio State University

Public Release: 14-Mar-2013
Public Health
Children of divorced parents more likely to start smoking
Both daughters and sons from divorced families are significantly more likely to initiate smoking in comparison to their peers from intact families, shows a new analysis of 19,000 Americans.

Contact: Dominic Ali
d.ali@utoronto.ca
416-978-6974
University of Toronto

Public Release: 13-Mar-2013
Journal of the National Cancer Institute
Lower incidence of genital warts in young girls
The incidence of genital warts, or condylomata, declined by 93 percent in girls given the HPV vaccine before the age of 14, according to a Swedish national registry study.
Merck, Sharp & Dohme

Contact: Press Office
pressinfo@ki.se
46-852-486-077
Karolinska Institutet

Public Release: 13-Mar-2013
Nature
Tapeworm DNA contains drug weak spots
Tapeworms cause devastating disease around the world and new treatments are urgently needed. This study describes possible targets on which currently licensed drugs could act, identified by genome sequencing. Re-using existing therapies will help to develop treatments more rapidly.

Contact: Aileen Sheehy
press.office@sanger.ac.uk
0044-012-234-92368
Wellcome Trust Sanger Institute

Public Release: 13-Mar-2013
Journal of the National Cancer Institute
Implementing HPV vaccinations at a young age is significant for vaccine effectiveness
Initial vaccinations for human papillomavirus (HPV) at a young age is important for maximizing quadrivalent HPV vaccine effectiveness according to a Swedish study published March 13 in the Journal of the National Cancer Institute.

Contact: Zachary Rathner
Zachary.Rathner@oup.com
919-677-2697
Journal of the National Cancer Institute

Public Release: 13-Mar-2013
Journal of Experimental Medicine
Breakthrough in battle against leukemia
Scientists at Griffith University's Institute for Glycomics have discovered a critical weakness in leukemic cells, which may pave the way to new treatments.

Contact: Helen Wright
helen.wright@griffith.edu.au
61-047-840-6565
Griffith University

Public Release: 13-Mar-2013
Science Translational Medicine
New monoclonal antibody developed that can target proteins inside cancer cells
Scientists from Memorial Sloan-Kettering Cancer Center and Eureka Therapeutics have collaborated to create a unique monoclonal antibody that can effectively reach inside a cancer cell.
NIH/National Cancer Institute, Leukemia and Lymphoma Society

Contact: Caitlin Hool
hoolc@mskcc.org
212-639-3573
Memorial Sloan-Kettering Cancer Center

Public Release: 13-Mar-2013
Journal of Biological Chemistry
Scientists discover novel chemical that controls cell behavior
It's the spread of the original cancer tumor that kills most people. That's why cancer researchers vigorously search for drugs that can prevent metastases, the spread of cancer. The research team co-led by Angela Wandinger-Ness, Ph.D., and Larry Sklar, Ph.D., has found a chemical compound that controls cell migration and adhesion, two important characteristics of metastatic cancer cells. The team recently published a paper describing how the first-in-class compound acts on various cells.

Contact: Michele Sequeira
MSequeira@salud.unm.edu
505-925-0486
University of New Mexico Cancer Center

Public Release: 13-Mar-2013
JAMA Internal Medicine
1 in 4 colonoscopies in Medicare patients found to be potentially inappropriate
A new study by researchers at the University of Texas Medical Branch at Galveston published online today in JAMA Internal Medicine shows that one out of four colonoscopies paid for by Medicare is potentially inappropriate under current screening guidelines set forth by the United States Preventive Services Task Force.
National Institutes of Health, Comparative Effectiveness Research on Cancer in Texas, Cancer Prevention Research Institute of Texas

Contact: Molly Dannenmaier
mjdannen@utmb.edu
409-771-5105
University of Texas Medical Branch at Galveston

Public Release: 13-Mar-2013
Molecular Therapy
Evidence supports blocking immune response to enhance viral therapy against solid tumors
Following several years of study, investigators have found more evidence that viral therapy to treat solid tumors can be enhanced by blocking the body's natural immune response.
National Institutes of Health

Contact: Mary Ellen Peacock
maryellen.peacock@nationwidechildrens.org
614-355-0492
Nationwide Children's Hospital

Public Release: 13-Mar-2013
Proceedings of the National Academy of Sciences
Polo takes the bait
A seemingly obscure gene in the female fruit fly that is only active in cells that will become eggs has led researchers at the Stowers Institute for Medical Research to the discovery of a atypical protein that lures, traps, and inactivates the powerful Polo kinase, widely considered the master regulator of cell division. Its human homolog, Polo-like kinase-1, is misregulated in many types of cancer.
Stowers Institute for Medical Research, American Cancer Society

Contact: Gina Kirchweger
gxk@stowers.org
816-806-1036
Stowers Institute for Medical Research

Showing releases 951-975 out of 1212.

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