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Showing releases 951-975 out of 1422.

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Public Release: 2-Apr-2016
ENDO 2016
Engineered ovary implant restores fertility in mice
Northwestern University scientists created a prosthetic ovary using a 3-D printer -- an implant that allowed mice that had their ovaries surgically removed to bear live young. The results will be presented Saturday, April 2, at the Endocrine Society's annual meeting, ENDO 2016, in Boston.
National Institutes of Health, Burroughs Wellcome Fund Career Award, National Science Foundation

Contact: Jenni Gingery
jgingery@endocrine.org
202-971-3655
The Endocrine Society

Public Release: 1-Apr-2016
Cancer Epidemiology, Biomarkers & Prevention
More Latinas screened for breast cancer after 'Promotora' visits
Latina women were nearly twice as likely to be screened for breast cancer after they were visited in their homes by trained community health workers, known as Promotoras, according to a study published in Cancer Epidemiology, Biomarkers and Prevention.
NIH/National Cancer Institute

Contact: Navneet Miller
navneet.miller@creation.io
415-262-5972
Kaiser Permanente

Public Release: 1-Apr-2016
ENDO 2016
Engineered ovary implant restores fertility in mice
Northwestern University scientists created a prosthetic ovary using a 3-D printer -- an implant that allowed mice that had their ovaries surgically removed to bear live young. The results will be presented Saturday, April 2, at the Endocrine Society's annual meeting, ENDO 2016, in Boston.
National Institutes of Health, Burroughs Wellcome Fund Career Award at the Scientific Interface, National Science Foundation Graduate Research Fellowship Program

Contact: Jenni Glenn Gingery
jgingery@endocrine.org
202-971-3655
The Endocrine Society

Public Release: 1-Apr-2016
Journal of Leukocyte Biology
Vaccine adjuvant protects against post-burn infection
Research findings published in the April 2016 issue of the Journal of Leukocyte Biology, suggests that the use of a FDA-approved drug may serve a dual purpose by protecting people who are at high risk of infection, including those with severe burns, cancer, and other conditions that may compromise their immune systems' ability to ward off disease.

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology

Public Release: 1-Apr-2016
Cancer Epidemiology, Biomarkers & Prevention
New study links coffee consumption to decreased risk of colorectal cancer
Researchers at the University of Southern California (USC) Norris Comprehensive Cancer Center of Keck Medicine of USC have found that coffee consumption, including decaf, instant and espresso, decreases the risk of colorectal cancer. Moreover, these benefits increase the more coffee you drink.

Contact: Mary Dacuma
mary.dacuma@med.usc.edu
323-865-7839
University of Southern California - Health Sciences

Public Release: 1-Apr-2016
Journal of Nanomedicine & Nanotechnology
NYU Tandon researcher synthesizes hybrid molecule that delivers a blow to malignant cells
A new molecule developed at NYU Tandon School of Engineering shows promise for treating breast cancer. The protein/polymer-gold nanoparticle composite, besides being easy to synthesize, can load up with drugs, carry them to malignant cells, and unload them where they can do the most damage with the least amount of harm to the patient. It was developed by Jin Kim Montclare, an associate professor in Tandon's Department of Chemical and Biomolecular Engineering.
National Science Foundation, Shiffrin Meyer Breast Cancer Discovery Fund, NIH/National Center for Advancing Translational Sciences

Contact: Karl Greenberg
karl.greenberg@nyu.edu
646-519-1996
NYU Tandon School of Engineering

Public Release: 1-Apr-2016
Genes & Development
Seeing cell to cell differences for first time explains symptoms of rare genetic disorders
Every cell in the body has two genomes, one from the mother and one from the father. Until now, researchers have lacked the tools to examine -- in a single cell -the exact readout from each genome to make RNA. Using a new technology that allows researchers to do just that, an interdisciplinary team examined a rare disease in which these two genomes are expressed differently throughout the body, even sometimes in the same organ.
National Institutes of Health, Alex's Lemonade Stand Foundation, St. Baldrick's Foundation, Burroughs-Wellcome Fund, National Science Foundation

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Public Release: 1-Apr-2016
ENDO 2016
BPA changes fetal development of the mammary gland, can raise breast cancer risk
A new culture system that tests the role of chemical exposure on the developing mammary gland has found that bisphenol A (BPA) directly affects the mammary gland of mouse embryos. The study results, to be presented Friday at the Endocrine Society's 98th annual meeting in Boston, show that these changes to embryonic mammary tissue occur at a dose comparable to that of humans' environmental exposure to BPA.

Contact: Jenni Gingery
jgingery@endocrine.org
202-971-3655
The Endocrine Society

Public Release: 31-Mar-2016
Aplidin shows positive results in pivotal Phase 3 clinical trial for multiple myeloma
Aplidin® has shown a statistically significant 35 percent reduction in the risk of progression or death over the comparator (p=0.0054). The study has met its primary endpoint.
PHARMAMAR

Contact: Paula Fernández
pfalarcon@pharmamar.com
34-638-796-215
Pharmamar

Public Release: 31-Mar-2016
Cell Chemical Biology
Living off the fat of the land
For more than 80 years scientists have thought that cancer cells fuel their explosive growth by soaking up glucose from the blood, using its energy and atoms to crank out duplicate sets of cellular components. But is this really true? Work in a metabolomics laboratory at Washington University in St. Louis suggests not.

Contact: Diana Lutz
dlutz@wustl.edu
314-935-5272
Washington University in St. Louis

Public Release: 31-Mar-2016
Pediatrics
'Cancer gene' twice as likely to be defective in children with autism
A large study by researchers with the UC Davis MIND Institute has found that a gene whose role is to suppress cellular damage from environmental stressors is nearly twice as likely to be defective in children with autism spectrum disorder, and that the deficit is also present in their fathers.
Simons Foundation Autism Research Initiative, NIH/National Institute of Environmental Health Sciences

Contact: Phyllis Brown
pkbrown@ucdavis.edu
916-734-9023
University of California - Davis Health System

Public Release: 31-Mar-2016
JAMA Oncology
Short overnight fasting linked to increased risk of breast cancer recurrence
In patients with breast cancer, a short overnight fast of less than 13 hours was associated with a statistically significant, 36 percent higher risk of breast cancer recurrence and a non-significant, 21 percent higher probability of death from the disease compared to patients who fasted 13 or more hours per night, report University of California, San Diego School of Medicine researchers.
NIH/National Cancer Institute

Contact: Yadira Galindo
ygalindo@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 31-Mar-2016
Blood
MicroRNA controls growth in highly aggressive B-cell lymphomas
A recent study by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine showed that a microRNA called miR-181a dampens signals from the cancer-driving NFκB protein pathway in the most aggressive large B-cell lymphomas.
Lymphoma Research Foundation

Contact: Patrick Bartosch
patrick.bartosch@med.miami.edu
305-243-8219
University of Miami Miller School of Medicine

Public Release: 31-Mar-2016
JAMA Oncology
Prolonged nightly fasting may reduce risk of breast cancer recurrence
Fasting less than 13 hours per night was associated with an increased risk for breast cancer recurrence in women with early-stage breast cancer, according to an article published online by JAMA Oncology.

Contact: Yadira Galindo
ygalindo@ucsd.edu
619-543-6163
The JAMA Network Journals

Public Release: 31-Mar-2016
JAMA Oncology
Urine test improves prediction of high-grade prostate cancer
A study published online in JAMA Oncology showed that an experimental urine test that detects genetic changes associated with prostate cancer identified 92 percent of men with elevated PSA levels who had more aggressive disease.

Contact: Karin Eskenazi
ket2116@columbia.edu
212-342-0508
Columbia University Medical Center

Public Release: 31-Mar-2016
Clinical Cancer Research
Brain cancer: Two essential amino acids might hold key to better outcomes
A new study suggests that the altered metabolism of two essential amino acids helps drive the development of the most common and lethal form of brain cancer. The findings suggest new ways to treat the malignancy, slow its progression and reveal its extent more precisely. The study shows that in glioblastoma, the essential amino acids methionine and tryptophan are abnormally metabolized due to the loss of key enzymes in GBM cells.
NIH/National Cancer Institute

Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Wexner Medical Center

Public Release: 31-Mar-2016
Plastic and Reconstructive Surgery
Ibuprofen doesn't increase bleeding risk after plastic surgery
Patients are often instructed not to take ibuprofen and other nonsteroidal anti-inflammatory drugs before or after surgery because of increased bleeding risk. But available evidence suggests that ibuprofen does not increase the risk of bleeding after plastic surgery procedures, according to a research review in the April issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons.

Contact: Connie Hughes
Connie.Hughes@wolterskluwer.com
646-674-6348
Wolters Kluwer Health

Public Release: 31-Mar-2016
Journal of Adolescent and Young Adult Oncology
Helping young adult cancer survivors adopt a healthy lifestyle
A healthy lifestyle is especially important for young adult and teenage survivors of cancer, and how health behavior messages related to diet, exercise, smoking, and alcohol consumption are developed and presented may impact their effectiveness in this population, according to an article in Journal of Adolescent and Young Adult Oncology (JAYAO).

Contact: Kathryn Ryan
kryan@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 31-Mar-2016
Cell
TGen and Mayo Clinic scientists issue report in Cell on advances in basal cell carcinoma
An article in the journal Cell by top scientists from the Translational Genomics Research Institute (TGen) and Mayo Clinic in Arizona details how two relatively new drugs are helping patients with basal cell carcinoma. Basal cell carcinoma is the most common type of skin cancer, producing nearly 2.8 million new cases annually in the US, and sunny Arizona has one of the world's highest incidences of skin cancer.

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute

Public Release: 31-Mar-2016
Clinical Cancer Research
Histone deacetylase inhibitors enhance immunotherapy in lung cancer models, say Moffitt researchers
Several new immunotherapeutic antibodies that inhibit checkpoint receptors on T cells to restimulate the immune system to target tumors have been approved to treat advanced stage lung cancer and melanoma; however, only 20 percent of lung cancer patients show a response to these agents. Moffitt Cancer Center researchers have identified a class of drugs that improve the activity of immunotherapeutic antibodies by stimulating the movement of T cells into a tumor and enhancing their activity.
National Institutes of Health

Contact: Lisa Chillura
lisa.chillura@moffitt.org
813-745-1353
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 31-Mar-2016
Cell
New study implicates unusual class of circular RNAs in cancer
Cancer cells are notorious for their genomes gone haywire, often yielding fusion proteins -- mash-ups of two disparate genes that, once united, assume new and harmful capabilities. Exactly how such genome scrambling impacts RNA, particularly the vast and mysterious world of non-coding RNA, has been largely unexplored.
National Institutes of Health

Contact: Jennifer Kritz
jkritz@bidmc.harvard.edu
617-667-7301
Beth Israel Deaconess Medical Center

Public Release: 31-Mar-2016
Research Ideas & Outcomes
Better cancer care for Indigenous Canadians with arts and dialogue in a new proposal
While the number of Indigenous Canadians diagnosed with cancer is growing, little is done to study and address their unique needs in a timely manner. Dr. Chad Hammond suggests an innovative research design, based on arts-based, participatory dialogue with stakeholders involved in cancer care for First Nation, Inuit, and Métis peoples. His grant proposal, submitted to the Canadian Institutes of Health Research postdoctoral fellowship competition, is published in the open-access journal Research Ideas and Outcomes.

Contact: Chad Hammond
chammond@uottawa.ca
Pensoft Publishers

Public Release: 30-Mar-2016
42nd Annual Meeting of the European Society for Blood and Marrow Transplantation
Cyclophosphamide, old dogs with new tricks?
During the EBMT Annual Meeting, many sessions and international speakers will discuss in depth the rejuvenated role of cyclophosphamide in stem cell transplantation.

Contact: Mélanie Chaboissier
melanie.chaboissier@ebmt.org
European Society for Blood and Marrow Transplantation

Public Release: 30-Mar-2016
Clinical Cancer Research
New compounds may aid in development of targeted therapies for a rare pediatric cancer
Two recently discovered compounds have shown promise in preclinical studies for treating Ewing sarcoma, a rare cancer that predominantly affects children and adolescents.

Contact: Beth Hinshaw Hall
beth.hinshawhall@vai.org
616-234-5519
Van Andel Research Institute

Public Release: 30-Mar-2016
Cancer Discovery
New mouse model for acute myeloid leukemia opens door to research, possible treatments
A novel mouse model of a highly lethal form of acute myeloid leukemia (AML) offers a new tool for scientists working to better understand this disease and research new therapeutic targets.
Ladies Auxiliary to the Veterans of Foreign Wars Postdoctoral Fellowship, CancerFree KIDS, University of Cincinnati, Cincinnati Children's, Leukemia and Lymphoma Society, NHLBI Progenitor Cell Biology Consortium, National Institutes of Health

Contact: Jim Feuer
jim.feuer@cchmc.org
513-636-4656
Cincinnati Children's Hospital Medical Center

Showing releases 951-975 out of 1422.

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