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Public Release: 30-Apr-2014
JAMA Dermatology
Study examines UV nail salon lamps, risk of skin cancer
Using higher-wattage ultra violet lamps at nail salons to dry and cure polish was associated with more ultra violet-A radiation being emitted, but the brief exposure after a manicure would require multiple visits for potential DNA damage and the risk for cancer remains small.

Contact: Jennifer Scott
The JAMA Network Journals

Public Release: 30-Apr-2014
94th AATS Annual Meeting
CT in the operating room allows more precise removal of small lung cancers
A new technique that brings CT imaging into the operating room will allow surgeons to precisely demarcate and remove small sub-centimeter lung nodules, leaving as much healthy tissue as possible, according to Raphael Bueno, M.D., of Brigham and Women's Hospital in Boston. His team is presenting the results of this late-breaking research at the 94th AATS Annual Meeting in Toronto, ON, Canada on April 30, 2014.

Contact: Nicole Baritot
American Association for Thoracic Surgery

Public Release: 30-Apr-2014
Journal of American Chemical Society
Cutting cancer to pieces: New research on bleomycin
In a new study, lead author Basab Roy -- a researcher at Arizona State University's Biodesign Institute -- describes bleomycin's ability to cut through double-stranded DNA in cancerous cells, like a pair of scissors. Such DNA cleavage often leads to cell death in particular types of cancer cells.

Contact: Joseph Caspermeyer
Arizona State University

Public Release: 30-Apr-2014
American Society of Breast Surgeons Annual Meeting
Surgeons and health care settings influence type of breast cancer surgery women undergo
Breast cancer is one of the few major illnesses for which physicians may not recommend a specific treatment option. North American women are more likely to opt for precautionary breast surgery when physicians don't specifically counsel against it, according to a new study.

Contact: Geoff Koehler
416-864-6060 x6537
St. Michael's Hospital

Public Release: 30-Apr-2014
Genes and Development
Damage control: Recovering from radiation and chemotherapy
Researchers at the University of California, San Diego School of Medicine report that a protein called beta-catenin plays a critical, and previously unappreciated, role in promoting recovery of stricken hematopoietic stem cells after radiation exposure.
National Institutes of Health, California Institute for Regenerative Medicine

Contact: Scott LaFee
University of California - San Diego

Public Release: 30-Apr-2014
Academic Pediatrics
Coached extracurricular activities may help prevent pre-adolescent smoking and drinking
Dartmouth researchers have found that tweens (preadolescents aged 10-14) who participate in a coached team sport a few times a week or more are less likely to try smoking. Their findings on the relationship between extracurricular activity and health risk behaviors are reported in 'The relative roles of types of extracurricular activity on smoking and drinking initiation among tweens,' which was recently published in Academic Pediatrics.
National Institutes of Health, NIH/National Cancer Institute

Contact: Robin Dutcher
The Geisel School of Medicine at Dartmouth

Public Release: 30-Apr-2014
American Society of Breast Surgeons Annual Meeting
Lymph node ultrasounds more accurate in obese breast cancer patients
Mayo Clinic research into whether ultrasounds to detect breast cancer in underarm lymph nodes are less effective in obese women has produced a surprising finding. Fat didn't obscure the images -- and ultrasounds showing no suspicious lymph nodes actually proved more accurate in overweight and obese patients than in women with a normal body mass index, the study found.

Contact: Sharon Theimer
Mayo Clinic

Public Release: 30-Apr-2014
International Journal of Epidemiology
Prostate cancer and blood lipids share genetic links
A new study by researchers at the University of California, San Diego School of Medicine, with colleagues in Norway, significantly refines the association, highlighting genetic risk factors associated with low density lipoprotein cholesterol and triglycerides as key players and identifying 17 related gene loci that make risk contributions to levels of these blood lipids and to prostate cancer.
Kristian Gerhard Jebsen Foundation, Centre for Molecular Medicine Norway

Contact: Scott LaFee
University of California - San Diego

Public Release: 30-Apr-2014
Water-based 'engine' propels tumor cells through tight spaces in the body
Johns Hopkins researchers have discovered how cancer cells spread through extremely narrow three-dimensional spaces in the body, identifying a propulsion system based on water and charged particles.
National Science Foundatoin, NIH/National Cancer Institute

Contact: Phil Sneiderman
Johns Hopkins University

Public Release: 29-Apr-2014
94th AATS Annual Meeting
Breath analysis offers non-invasive method to detect early lung cancer
Researchers at the University of Louisville School of Medicine are using breath analysis to detect the presence of lung cancer. Preliminary data indicate that this promising noninvasive tool offers the sensitivity of PET scanning, and has almost twice the specificity of PET for distinguishing patients with benign lung disease from those with early stage cancer. Michael Bousamra II, M.D., Associate Professor, Department of Cardiovascular and Thoracic Surgery, is presenting the results of the study at the AATS 2014 Conference on Apr. 29, 2014.

Contact: Nicole Baritot
American Association for Thoracic Surgery

Public Release: 29-Apr-2014
Journal of Clinical Endocrinology and Metabolism
Vitamin D may raise survival rates among cancer patients
Cancer patients who have higher levels of vitamin D when they are diagnosed tend to have better survival rates and remain in remission longer than patients who are vitamin D-deficient, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

Contact: Jenni Glenn Gingery
The Endocrine Society

Public Release: 29-Apr-2014
Genome Research
Immunogenic mutations in tumor genomes correlate with increased patient survival
Developing immunotherapies for cancer is challenging because of significant variability among tumors and diversity in human immune types. In a study published online today in Genome Research, researchers examined the largest collection of tumor samples to date to predict patient-specific tumor mutations that may activate the patient's immune system, paving the way for more successful, personalized cancer immunotherapy.
BC Cancer Foundation, Canadian Institutes of Health Research, US Department of Defense

Contact: Peggy Calicchia
Cold Spring Harbor Laboratory

Public Release: 29-Apr-2014
Microfluidic technology reveals potential biomarker for early pancreatic cancer
The findings, published in Gastroenterology, revealed circulating pancreas cells seed the bloodstream before tumors can be detected using current clinical tests. The data suggest that the detection of pancreas cells in the blood may be an early sign of cancer.
Naitonal Institutes of Health

Contact: Shantell M. Kirkendoll
University of Michigan Health System

Public Release: 29-Apr-2014
94th AATS Annual Meeting
Major lung resection safer than ever, especially at the busiest hospitals
A major new study using data from the National Cancer Data Base details the impact of annual hospital volume on 30- and 90-day mortality rates. Investigators found that major lung surgery has become progressively safer over the last few decades, although higher death rates at low-volume hospitals and an unexpected increase in mortality at 90 days compared to 30 days were observed. The study further suggests that choosing a center that performs major lung surgery regularly can have a strong impact on survival.

Contact: Nicole Baritot
American Association for Thoracic Surgery

Public Release: 29-Apr-2014
94th AATS Annual Meeting
Poor QOL doesn't predict low survival in high-risk lung cancer patients undergoing surgery
High-risk operable lung cancer patients have poorer quality of life scores than the normal US population. However surgery can still be undertaken safely: Low global quality of life scores were not associated with lower survival, recurrence-free rate, or for higher risk for adverse events following sublobar resection, a major surgical procedure.

Contact: Nicole Baritot
American Association for Thoracic Surgery

Public Release: 29-Apr-2014
ACS Nano
Brain tumor cells penetrated by tiny, degradable particles carrying genetic instructions
Working together, Johns Hopkins biomedical engineers and neurosurgeons report that they have created tiny, biodegradable 'nanoparticles' able to carry DNA to brain cancer cells in mice. The team says the results of their proof of principle experiment suggest that such particles loaded with 'death genes' might one day be given to brain cancer patients during neurosurgery to selectively kill off any remaining tumor cells without damaging normal brain tissue.
NIH/National Institute of Biomedical Imaging and Bioengineering, NIH/National Cancer Institute, Maryland Stem Cell Research Fund, Technology Development Corporation

Contact: Catherine Kolf
Johns Hopkins Medicine

Public Release: 29-Apr-2014
Lancet Oncology
NCI, NCRI and EORTC outline risk-assessment approach for biomarker-driven cancer clinical trials
In an article published in The Lancet Oncology, an NCI, NCRI, and EORTC working group outline a practical risk-management approach for effective integration of biomarkers into cancer clinical trials. Their work provides the international community with a set of common principles by which biomarkers can be integrated into clinical trials, exchange of data can be facilitated, quality promoted, and research accelerated while simultaneously respecting local approaches and legislation.
EORTC Charitable Trust, UK Department of Health

Contact: John Bean
European Organisation for Research and Treatment of Cancer

Public Release: 29-Apr-2014
Nature Communications
UNC researchers discover 'master regulator' role for little-known protein in cancer cells
Researchers in the UNC School of Medicine found that the protein DAZAP1 plays a key role in the regulation of many genes through a process known as alternative splicing, and when highly expressed in cancer cell line experiments, DAZAP1 was shown to inhibit several types of cancer cells from dividing and moving. The discovery, published in the journal Nature Communications, marks the first time this little-known protein has been characterized in relation to cancer development and tumor growth.

Contact: Mark Derewicz
University of North Carolina Health Care

Public Release: 29-Apr-2014
Clinical Cancer Research
CNIO team presents a new strategy to personalise cancer therapies
Researchers led by Manuel Hidalgo, Vice-Director of Translational Research at CNIO, have developed a new strategy to personalized medicine in advanced cancer patients with a poor prognosis. The study has been published in the journal Clinical Cancer Research. Applying this new tool, the treatments induced clinical responses in up to 77 percent of patients, either through the stabilization of their condition or through a partial clinical response.

Contact: Nuria Noriega
Centro Nacional de Investigaciones Oncologicas (CNIO)

Public Release: 29-Apr-2014
Journal of Health Communication
Anti-smoking TV ads should use anger, Dartmouth-Cornell study suggests
Anti-smoking television advertisements that appeal to viewers' emotions are more persuasive when they use anger rather than sadness, a Dartmouth-Cornell study suggests.

Contact: John Cramer
Dartmouth College

Public Release: 29-Apr-2014
Genome Biology
Like puzzle pieces, 3-D genomics holds a key to classifying human diseases
To solve a puzzle, you need to recognize shapes, patterns and a particular kind of order. In much the same way, researchers at McGill University have discovered that the 3-D shape of a leukemia cell's genome holds a key to solving the puzzle of human diseases. The researchers report their findings in the open access journal Genome Biology.

Contact: Cynthia Lee
McGill University

Public Release: 28-Apr-2014
Journal of Biological Chemistry
Researchers identify potential new strategy to treat ovarian cancer
Scientists studying cancerous tumor tissues in a laboratory believe they have identified a potential new strategy to treat ovarian cancer -- which affects around 7,000 women in the UK each year.

Contact: Alison Barbuti
University of Manchester

Public Release: 28-Apr-2014
Current Oncology
Breast cancer patients place huge emphasis on gene expression profiling test
Gene expression profiling tests play a critical role when women with early-stage breast cancer decide whether to have chemotherapy, but many of them do not fully understand what some of the test results mean, new research suggests.
Cancer Care Ontario, Ontario Institute for Cancer Research

Contact: Leslie Shepherd
St. Michael's Hospital

Public Release: 28-Apr-2014
Well-informed patients key to accepting gene-based drug dosing
A new study out of Western University led by Dr. Michael Rieder, illustrates the need for a lot more education around pharmacogenetics -- the study of how a patient's genes can affect drug reaction and dosage. Pharmacogenetics promises to optimize patient response to therapy, but this is the first study to really investigate how patients perceive this kind of genetic testing, and whether those perceptions differ when it comes to parents and their children.
Schulich School of Medicine & Dentistry, Western University

Contact: Kathy Wallis
519-661-2111 x81136
University of Western Ontario

Public Release: 28-Apr-2014
European Journal of Immunology
One cell type may quash tumor vaccines
Researchers suspect that many cancer vaccines fail because the immune cells that would destroy the tumor are actively suppressed. Now, researchers at Thomas Jefferson University have found that a single cell type may be to blame for the suppression, paving the way to better cancer vaccine design.

Contact: Edyta Zielinska
Thomas Jefferson University

Showing releases 976-1000 out of 1232.

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