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Public Release: 14-May-2015
2015 ASCO Annual Conference
PharmaMar announces new advances in oncology at ASCO 2015 for compounds YONDELIS® and PM1183
PharmaMar announces new advances in oncology at ASCO 2015 for its compounds YONDELIS® and PM1183 highlighting data in small cell lung cancer, soft tissue sarcoma, and mesothelioma.

Contact: Carolina Pola

Public Release: 14-May-2015
New release of Glioblastoma Atlas sheds light on deadly disease
Robust new data added to the Ivy Glioblastoma Atlas Project changes the scope and impact of this publicly available resource for researchers and clinicians searching for treatments for this most deadly and aggressive of brain cancers, glioblastoma multiforme.
Ben and Catherine Ivy Foundation

Contact: Rob Piercy
Allen Institute

Public Release: 14-May-2015
JAMA Otolaryngology - Head & Neck Surgery
Study examines treatment factors associated with oral cavity cancer survival
The surgical procedure known as neck dissection to remove lymph nodes and receiving treatment at academic or research institutions was associated with improved survival in patients with stages I and II oral cavity squamous cell cancer, according to a report published online by JAMA Otolaryngology-Head & Neck Surgery.

Contact: Ziba Kashef
The JAMA Network Journals

Public Release: 14-May-2015
Proceedings of the National Academy of Sciences
Georgia State research paves way for early detection of liver cancer
Led by Georgia State University, researchers have developed the first robust and noninvasive detection of early stage liver cancer and liver metastases, in addition to other liver diseases, such as cirrhosis and liver fibrosis.
National Institutes of Health

Contact: Brian Mullen
Georgia State University

Public Release: 14-May-2015
Frontiers in Neurology
Geneticists clock genetic differences between 'larks' and 'owls'
A new study from University of Leicester uncovers clues for 'morningness' and 'eveningness.'
Biotechnology and Biological Sciences Research Council

Contact: Dr Eran Tauber (PhD)
University of Leicester

Public Release: 14-May-2015
Molecular Cell
Scientists discover how a promising anti-leukemia drug harms cancer cells
Due to overwhelming evidence of their effectiveness in mice, inhibitors of the leukemia protein BRD4, including the drug JQ1, moved into clinical trials starting in 2013. There are 12 trials targeting BRD4 in progress. Last year, clinical trial findings indicated that an oral inhibitor of BRD4 similar to JQ1 had led to complete remission in some patients. Now a team at CSHL has determined the pathway through which JQ1 acts.
National Institutes of Health, Alex's Lemonade Stand Foundation, V Foundation, Martin Sass Foundation, Lauri Strauss Leukemia Foundation, Burroughs Wellcome Fund, Japan Society for the Promotion of Science, Boehringer Ingelheim Fonds

Contact: Peter Tarr
Cold Spring Harbor Laboratory

Public Release: 14-May-2015
Unemployment linked to rise in prostate cancer deaths
The knock-on effects of the economic downturn have been explored in economy and psychology. Now researchers are examining the effects of unemployment on an even darker subject -- cancer mortality. One would think that dealing with unemployment was challenge enough. But according to the latest research published in ecancermedicalscience, rises in unemployment are associated with significant increases in prostate cancer mortality.

Contact: Audrey Nailor

Public Release: 14-May-2015
Cancer Research
Contraceptive and cholesterol-lowering drugs used to treat cancer
The combination of a cholesterol-lowering drug, Bezafibrate, and a contraceptive steroid, Medroxyprogesterone Acetate, could be an effective, non-toxic treatment for a range of cancers, researchers at the University of Birmingham have found.

Contact: Luke Harrison
University of Birmingham

Public Release: 14-May-2015
JAMA Oncology
Smoking induces early signs of cancer in cheek swabs
DNA damage caused by smoking can be detected in cheek swabs, finds research published today in JAMA Oncology. The study provides evidence that smoking induces a general cancer program that is also present in cancers which aren't usually associated with it -- including breast and gynecological cancers.
Eve Appeal

Contact: Wesley Hutchins
University College London

Public Release: 14-May-2015
2015 ASCO Annual Conference
Experimental immunotherapy shows high response rate in advanced lung cancer
An early phase study testing an anti-PDL1 agent in combination with standard chemotherapy in the treatment of advanced non-small cell lung cancer has provided promising early results, prompting multiple phase III studies in lung cancer.

Contact: Karen Teber
Georgetown University Medical Center

Public Release: 13-May-2015
European Journal of Epidemiology
No link found between PTSD and cancer risk
In the largest study to date that examines post-traumatic stress disorder (PTSD) as a risk factor for cancer, researchers from Boston University School of Medicine, have shown no evidence of an association.
NIH/National Institute of Mental Health

Contact: Gina DiGravio
Boston University Medical Center

Public Release: 13-May-2015
Scientists discover new molecules that kill cancer cells and protect healthy cells
A new family of molecules that kill cancer cells and protect healthy cells could be used to treat a number of different cancers, including cervical, breast, ovarian and lung cancers. Research published in EBioMedicine shows that as well as targeting and killing cancer cells, the molecules generate a protective effect against toxic chemicals in healthy cells.

Contact: Nienke Swankhuisen

Public Release: 13-May-2015
Starving cancer cells instead of feeding them poison
An enzyme-drug that prevents the essential nutrient asparagine from reaching cancer cells seem an effective way to kill them, but that enzyme-drug also does away with the nutrient glutamine that all cells need. Now a simulation has directed the mutation of the enzyme so that, in wet labs, it left normal cells unharmed in Petri dishes and cancer cells dead in test tubes. Lab tests are underway with mice. If successful, human tests are next.
Sandia National Laboratories' Laboratory-Directed Research and Development

Contact: Neal Singer
DOE/Sandia National Laboratories

Public Release: 13-May-2015
Researcher discovers molecules that could kill cancer while protecting healthy cells
Researchers have identified new molecules that kill cancer cells while protecting healthy cells and that could be used to treat a variety of different cancers. The research shines a light on what happens to cells at the moment they become cancerous.

Contact: Nick Manning
University of Waterloo

Public Release: 13-May-2015
2015 ASCO Annual Conference
Myriad showcases its pioneering research at the 2015 ASCO Annual Meeting
Myriad will present data from 19 clinical studies at the 2015 American Society of Clinical Oncology annual meeting to be held May 29-June 2, 2015 in Chicago, Ill. Key podium presentations will highlight new prospective research programs with advanced companion diagnostic and molecular diagnostic tests aimed at revolutionizing how we treat and prevent cancers. Myriad's pioneering research in personalized medicine will be showcased.

Contact: Ron Rogers
Myriad Genetics, Inc.

Public Release: 13-May-2015
New England Journal of Medicine
Drug extends survival of patients with metastatic colorectal cancer
A drug developed 50 years ago and abandoned because it was considered to be too toxic has gained a second life in an international clinical trial. Research led by scientists at Dana-Farber Cancer Institute showed the drug and a potentiating agent lengthened the lives of patients with metastatic colorectal cancer, all of whom had exhausted available standard treatments.
Taiho Oncology-Taiho Pharmaceutical

Contact: Anne Doerr
Dana-Farber Cancer Institute

Public Release: 13-May-2015
Journal of Clinical Oncology
Moffitt researchers say androgen deprivation therapy may lead to cognitive impairment
Cognitive impairment can occur in cancer patients who are treated with a variety of therapies, including radiation therapy, hormone therapy, and chemotherapy. After chemotherapy treatment it is commonly called 'chemo brain.' Signs of cognitive impairment include forgetfulness, inability to concentrate, problems recalling information, trouble multi-tasking and becoming slower at processing information. The number of people who experience cognitive problems following cancer therapy is broad, with an estimate range of 15 to 70 percent.
National Cancer Institute

Contact: Kim Polacek
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 13-May-2015
Lancet Oncology
Stereotactic Ablative Radiotherapy achieves better overall survival than surgery for early lung cancer
Patients with operable stage I non-small cell lung cancer (NSCLC) could achieve better overall survival rates if treated with Stereotactic Ablative Radiotherapy (SABR) rather than the current standard of care -- invasive surgery -- according to research from a phase III randomized international study from The University of Texas MD Anderson Cancer Center.

Contact: Laura Sussman
University of Texas M. D. Anderson Cancer Center

Public Release: 13-May-2015
2015 ASCO Annual Conference
Tumor sequencing study highlights benefits of profiling healthy tissue as well
As the practice of genetically profiling patient tumors for clinical treatment decision making becomes more commonplace, a recent study from The University of Texas MD Anderson Cancer Center suggests that profiling normal DNA also provides an important opportunity to identify inherited mutations that could be critical for patients and their families.

Contact: Clayton R. Boldt
University of Texas M. D. Anderson Cancer Center

Public Release: 13-May-2015
2015 ASCO Annual Conference
New cancer treatment and prevention studies signal major advances for children and adults
The American Society of Clinical Oncology today announced results from four major studies to be presented at ASCO's 51st Annual Meeting, May 29-June 2, in Chicago. Findings showed that use of a widely available vitamin pill reduces the risk of non-melanoma skin cancers; that early chemotherapy extends the lives of men with advanced prostate cancers; and that new therapies can improve outcomes for children with a rare form of kidney cancer and adults with relapsed multiple myeloma.

Contact: Alise Fisher
American Society of Clinical Oncology

Public Release: 13-May-2015
2015 ASCO Annual Conference
Variations in liver cancer attributable to hepatitis virus variations
Significant clinical variations exist among patients with the most common type of liver cancer called hepatocellular carcinoma, depending on the viral cause of the disease --hepatitis B virus or hepatitis C virus. These differences suggest that hepatitis status should be considered when developing treatment plans for newly diagnosed patients, according to researchers at The University of Texas MD Anderson Cancer Center.
National Institutes of Health

Contact: Laura Sussman
University of Texas M. D. Anderson Cancer Center

Public Release: 13-May-2015
Journals of Gerontology: Medical Sciences
When it comes to testosterone, more isn't always better
A study connects increased diabetes risk and higher levels of testosterone to prostate enlargement.

Contact: Andrea Estrada
University of California - Santa Barbara

Public Release: 13-May-2015
Journal of National Cancer Institute
Protein FGL2 may have potential as therapy target for brain cancer
Blocking FGL2, a protein known to promote cancer, may offer a new strategy for treating brain cancer, according to a study at The University of Texas MD Anderson Cancer Center.
National Institutes of Health

Contact: Ron Gilmore
University of Texas M. D. Anderson Cancer Center

Public Release: 13-May-2015
Research shows how antibodies produce vaccine-like effect against tumors
New research at Rockefeller University shows how antibody therapy destroys tumor cells then prompts a patient's immune system to form immunological memory that can suppress the same cancer should it try to return.

Contact: Wynne Parry
Rockefeller University

Public Release: 13-May-2015
2015 ASCO Annual Conference
Economic burden of cancer extends into survivorship
A new study finds the economic burden of cancer extends beyond diagnosis and treatment, and concludes that cancer survivors face thousands of dollars of excess medical expenses every year.
American Cancer Society

Contact: David Sampson
American Cancer Society

Showing releases 976-1000 out of 1324.

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