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Showing releases 976-1000 out of 1182. << < 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 > >>
Public Release: 17-Dec-2012
 Journal of Clinical InvestigationJCI early table of contents for Dec. 17, 2012 This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be publish online, Monday, Dec. 17, 2012, in the JCI: Harnessing the ID in glioma; An inflammatory protein plays an unexpected rol in lung infections; Breast cancer cells interact with non-cancerous tissue to drive metastasis; Intestinal wound repair relies on ANXA1; and many more. Contact: Jillian Hurst
Public Release: 17-Dec-2012
Journal of Clinical InvestigationHarnessing the ID in glioma In this issue of the Journal of Clinical Investigation, researchers led by Antonio Iavarone at Columbia University report on the role of ID proteins in glioma. 
NIH/National Cancer Institute, NIH/National Institute of Neurological Disorders and Stroke
Contact: Jillian Hurst
Public Release: 17-Dec-2012
American Society for Cell Biology 2012 Annual MeetingNew type of cell division discovered The new type of cell division, which the researchers named klerokinesis, could be an evolutionary failsafe mechanism that rescues a range of cell functions during embryonic development to genetic repair that can become abnormal if cell division fails to produce normal cells. Contact: Cathy Yarbrough
Public Release: 17-Dec-2012
American Society for Cell Biology 2012 Annual MeetingBreast cancer cells growing in 3D-matrix revert to normal Cancer cells in lab cultures have not "forgotten" how to be healthy since they can be guided back into their "normal" growth program by giving them the right cues. Applying compressive force to malignant breast epithelial cells growing within a laminin-rich 3D extracellular matrix caused them to turn into highly organized, growth-arrested acini, the milk-secreting spherical structures that are central to breast tissue. Contact: Cathy Yarbrough
Public Release: 17-Dec-2012
American Society for Cell Biology 2012 Annual MeetingChanges in progenitor cell population in breast may be overlooked factor in breast cancer DNA mutations that accumulate as women age are not the sole contributor to higher frequency of breast cancer in women over 50. In breast cancer and aging, changes in the populations of progenitor cells in breast tissue may be a powerful and until now overlooked factor. Contact: Cathy Yarbrough
Public Release: 17-Dec-2012
Annals of Internal MedicineAnnals of Internal Medicine tip sheet for Dec. 18, 2012 Below is information about articles being published in the Dec. 18 issue of Annals of Internal Medicine. The information is not intended to substitute for the full articles as a source of information. Annals of Internal Medicine attribution is required for all coverage. Contact: Megan Hanks
Public Release: 17-Dec-2012
Advanced MaterialsNew technology allows scientists to capture and preserve cancer cells circulating in the bloodstream Scientists from the RIKEN Advanced Science Institute in Japan and University of California Los Angeles report a new nanoscale Velcro-like device that captures and releases tumor cells that have broken away from primary tumors and are circulating in the bloodstream. This new nanotechnology could be used for cancer diagnosis and give insight into the mechanisms of how cancer spreads throughout the body. Contact: Juliette Savin
Public Release: 17-Dec-2012
Proceedings of the National Academy of SciencesDuke Medicine News new immune therapy successfully treats brain tumors in mice Using an artificial protein that stimulates the body's natural immune system to fight cancer, a research team at Duke Medicine has engineered a lethal weapon that kills brain tumors in mice while sparing other tissue. If it can be shown to work in humans, it would overcome a major obstacle that has hampered the effectiveness of immune-based therapies.
National Institutes of Health, Pediatric Brain Tumor Foundation, Ben and Catherine Ivy Foundation
Contact: Sarah Avery
Public Release: 17-Dec-2012
Archives of Internal MedicineStudy examines risk reduction and screening for ovarian cancer among women following BRCA testing Following BRCA testing, many women who are non-BRCA carriers undergo risk-reducing procedures and additional ovarian cancer screenings, despite limited data to determine the effectiveness of these interventions among the general population. Contact: Elizabeth Fernandez
Public Release: 17-Dec-2012
American Society for Cell Biology 2012 Annual MeetingTo revert breast cancer cells, give them the squeeze UC Berkeley researchers have found that compression can guide malignant breast cells back to a normal growth pattern. The findings, to be presented Dec. 17 at the American Society for Cell Biology meeting, demonstrate the influence of mechanical forces on a cell's destiny.
National Institutes of Health
Contact: Sarah Yang
Public Release: 17-Dec-2012
CancerSnack attack: Eating unhealthy snack foods may affect cancer risk in patients with Lynch syndrome A new analysis has found that loading up on snack foods may increase cancer risk in individuals with an inborn susceptibility to colorectal and other cancers. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study suggests that an eating pattern low in snack foods could help these individuals -- who have a condition called Lynch syndrome -- lower their risk. Contact: Amy Molnar
Public Release: 17-Dec-2012
OncogeneStudy uncovers mechanism used by BRCA1 to suppress tumors A new reveals how a well-known tumor suppressor gene may be functioning to stop cancer cell growth. The findings focus on the gene BRCA1. "There is a debate in the scientific community about whether BRCA1 enzymatic activity is important in tumor suppressor function," says Ronit I. Yarden, PhD. "My lab thinks it is."
Please see complete list in body of press release
Contact: Karen Mallet
Public Release: 16-Dec-2012
Nature BiotechnologyNew technique could make cell-based immune therapies for cancer safer and more effective A team led by Michel Sadelain, M.D., Ph.D., Director of the Center for Cell Engineering at Memorial Sloan-Kettering Cancer Center, has shown for the first time the effectiveness of a new technique that could allow the development of more-specific, cell-based immune therapies for cancer.
Mr. William H. and Mrs. Alice Goodwin, Commonwealth Foundation for Cancer Research, and others
Contact: Andrea Molinatti
Public Release: 15-Dec-2012
Journal of Thoracic OncologyStudy shows immunohistochemistry is reliable screening tool for ALK rearrangement A recent study published in the January 2013 issue of the International Association for the Study of Lung Cancer's Journal of Thoracic Oncology, concludes immunohistochemistry is a reliable screening tool for identification of ALK rearrangement. Contact: Kristal Griffith
Public Release: 15-Dec-2012
Journal of Thoracic OncologyStudy confirms prognostic value of new IASLC/ATS/ERS adenocarcinoma sub-classification A new study published in the January 2013 issue of the International Association for the Study of Lung Cancer's Journal of Thoracic Oncology, concludes the new IASLC/ATS/ERS classification identifies histologic subtypes of lung adenocarcinomas with prognostic value among Japanese patients. Contact: Kristal Griffith
Public Release: 15-Dec-2012
Journal of Thoracic OncologyStudy shows COPD is not independent risk factor for lung cancer A recent study published in the January 2013 issue of the International Association for the Study of Lung Cancer's Journal of Thoracic Oncology, concludes that COPD is not an independent risk factor for lung cancer. Contact: Kristal Griffith
Public Release: 14-Dec-2012
Journal of the National Cancer InstituteLow adiponcetin associated with increased pancreatic cancer risk Low prediagnostic levels of circulating adiponectin were associated with an increased risk of pancreatic cancer, according to a study published December 14 in the Journal of the National Cancer Institute. Contact: Zachary Rathner
Public Release: 14-Dec-2012
Cancer DiscoveryHard-to-treat Myc-driven cancers may be susceptible to drug already used in clinic Drugs that are used in the clinic to treat some forms of breast and kidney cancer and that work by inhibiting the signaling molecule mTORC1 might have utility in treating some of the more than 15 percent of human cancers driven by alterations in the Myc gene, according to data from a preclinical study published in Cancer Discovery. Contact: Jeremy Moore
Public Release: 14-Dec-2012
Molecular Cancer ResearchPitt Cancer Institute finds new targets for drugs to defeat aggressive brain tumor University of Pittsburgh Cancer Institute researchers have identified over 125 genetic components in a chemotherapy-resistant, brain tumor-derived cell line, which could offer new hope for drug treatment to destroy the cancer cells. The potential drug targets were identified after testing more than 5,000 genes derived from glioblastoma multiforme.
National Institutes of Health, National Brain Tumor Society
Contact: Allison Hydzik
Public Release: 14-Dec-2012
Clinical Cancer ResearchThe HER2 paradox: HER2-positive stem cells found in HER2-negative breast cancer A multicenter study led by researchers at UC Davis describes new, paradoxical characteristics of the most common type of breast cancer.
National Institutes of Health, US Department of Energy Office of Science
Contact: Dorsey Griffith
Public Release: 14-Dec-2012
54th Annual Meeting of the American Society of HematologyIbrutinib has 'unprecedented' impact on mantle cell lymphoma An international study of ibrutinib in people with relapsed or refractory mantle cell lymphoma continues to show unprecedented and durable results with few side effects. Contact: Scott Merville
Public Release: 13-Dec-2012
Journal of the National Cancer InstituteDespite hype, costly prostate cancer treatment offers little relief from side effects Prostate cancer patients receiving the costly treatment known as proton radiotherapy experienced minimal relief from side effects such as incontinence and erectile dysfunction, compared to patients undergoing a standard radiation treatment called intensity modulated radiotherapy, Yale School of Medicine researchers report in the Journal of the National Cancer Institute.
NIH/National Cancer Institute, National Institutes of Health, NIH/National Center for Research Resources, NIH/National Center for Advancing Translational Sciences
Contact: Karen N. Peart
Public Release: 13-Dec-2012
Science Translational Medicine'Two-faced' cells discovered in colon cancer A "two-faced" group of cells at work in human colon cancer can either suppress or promote tumor growth. These cells are a subset of T-regulatory (Treg) cells, known to suppress immune responses in healthy people. The discovery of Treg diversity in cancer and its role in control of cancer inflammation may lead to new approaches for therapeutics. Contact: Marla Paul
Public Release: 13-Dec-2012
Clinical Gastroenterology and HepatologyRural dwellers less likely to follow cancer screening guidelines People who reside in rural areas of Utah are less likely to follow colorectal cancer screening recommendations than their urban counterparts, according to researchers from Huntsman Cancer Institute at the University of Utah. Contact: Linda Aagard
Public Release: 13-Dec-2012
eLifeTeam solves mystery associated with DNA repair Scientists have long sought to understand how a DNA repair protein, known as RecA in bacterial cells, helps broken DNA find a way to bridge the gap. In a new study, researchers report they have identified how the RecA protein does its job.
National Science Foundation, Howard Hughes Medical Institute
Contact: Diana Yates
Showing releases 976-1000 out of 1182. << < 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 > >>
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