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Showing releases 976-1000 out of 1299.

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Public Release: 9-Jul-2015
JAMA Oncology
Two-thirds of teen and young adult cancer patients facing end of life use aggressive measures
More than two-thirds of adolescents and young adults dying of cancer utilized one or more aggressive interventions in the last month of life, according to a retrospective study published July 9 in JAMA Oncology. The findings suggest the need for more research into whether patients have been adequately supported to contemplate their end-of-life options or whether the pattern reflects their well-considered wishes.
Cancer Research Network, NIH/National Cancer Institute

Contact: Irene Sege
Dana-Farber Cancer Institute

Public Release: 9-Jul-2015
JAMA Oncology
Studies, commentary, editorial, editor's note focus on teens, adults at end of life
A related package of articles published online by JAMA Oncology focuses on end-of-life care for teens and young adults and advance care planning for patients with cancer. The package of articles includes two original investigations, an invited commentary, an editorial, an accompanying editor's note and an author audio interview.

Contact: Irene Sege
The JAMA Network Journals

Public Release: 9-Jul-2015
New technique for precise light-activated chemotherapy drugs
A new technique that uses light to activate chemotherapy drugs in specific cells shows promise as a way to improve the effectiveness of cancer therapies while preventing severe side effects, according to a study published July 9 in Cell. The approach could be used to treat a range of tumors with unprecedented precision by making existing cancer drugs sensitive to light -- an approach that requires less time and effort compared with traditional drug discovery programs.

Contact: Joseph Caputo
Cell Press

Public Release: 9-Jul-2015
UEA scientists separate medical benefits of cannabis from unwanted side effects
Scientists at the University of East Anglia have found a way to separate medical benefits of cannabis from its unwanted side effects. The research was carried out in mice, but it is hoped that the breakthrough will pave the way for safe cannabis-based therapies that do not cause alterations in mood, perception or memory. Last year the team discovered how the main psychoactive ingredient in cannabis, known as THC, reduces tumor growth in cancer patients.

Contact: Lisa Horton
University of East Anglia

Public Release: 9-Jul-2015
Nature Communications
Study advances potential of tumor genome sequencing and DNA-based blood tests in precision treatment
In a genome-sequencing study of pancreatic cancers and blood in 101 patients, Johns Hopkins Kimmel Cancer Center scientists say they found at least one-third of the patients' tumors have genetic mutations that may someday help guide precision therapy of their disease. Results of blood tests to detect DNA shed from tumors, they say, also predicted cancer recurrence more than half a year earlier than standard imaging methods.
American Association for Cancer Research Stand Up To Cancer-Dream Team, NIH/National Cancer Institute FasterCures, European Community's Seventh Framework Programme, Swim Across America, Dennis Troper and Susan Wojcicki

Contact: Vanessa Wasta
Johns Hopkins Medicine

Public Release: 9-Jul-2015
JAMA Oncology
Aggressive cancer treatment near end of life persists despite rise in advance planning efforts
In a review of nearly 2,000 surveys with people whose loved ones died of cancer, researchers led by Johns Hopkins experts say they found a 40 percent increase over a 12-year period in the number of patients with cancer who participated in one form of advance care planning -- designating durable power of attorney privileges to a loved one -- but no corresponding impact on their rates of aggressive medical care received in the last weeks of life.
NIH/National Institute on Aging, NIH/National Cancer Institute

Contact: Vanessa Wasta
Johns Hopkins Medicine

Public Release: 9-Jul-2015
The Lancet
Less intensive chemo avoids irreversible side effects in children's cancer
Children with a rare type of cancer called Wilms' tumor who are at low risk of relapsing can now be given less intensive treatment, avoiding a type of chemotherapy that can cause irreversible heart problems in later life.
Cancer Research UK

Contact: Ailsa Stevens
Cancer Research UK

Public Release: 9-Jul-2015
Researchers call for support for data in the cloud to facilitate genomics research
Today in the journal Nature prominent researchers from Canada, Europe and the US have made a powerful call to major funding agencies, asking them to commit to establishing a global genomic data commons in the cloud that could be easily accessed by authorized researchers worldwide.

Contact: Christopher Needles
Ontario Institute for Cancer Research

Public Release: 9-Jul-2015
2D Materials
Super graphene helps boost chemotherapy treatment
Silver is often used as a coating on medical equipment used for chemotherapy. The problem is that this silver coating can break down drugs. Now, researchers have found a graphene coating that will help boost the effect of chemotherapy.
Norwegian Ph.D. Network on Nanotechnology for Microsystems, Research Council of Norway

Contact: Justin Wells
Norwegian University of Science and Technology

Public Release: 9-Jul-2015
BMC Genomics
'Jumping genes' may drive esophageal cancer
Cancer Research UK scientists have found that 'jumping genes' may add to the genetic chaos behind more than three-quarters of esophageal cancer cases.

Contact: Emily Head
Cancer Research UK

Public Release: 9-Jul-2015
Promising drug for childhood acute leukemia -- where to next?
A new Australian study shows that a recently-developed drug, already used safely in adult leukemia clinical trials, holds great promise for some children with an aggressive form of cancer known as acute lymphoblastic leukemia.
NIH/National Cancer Institute, National Health and Medical Research Council of Australia

Contact: Alison Heather
Children's Cancer Institute Australia

Public Release: 9-Jul-2015
American Thoracic Society International Conference
New program using CT technology helping doctors better detect lung cancer
Long-time smokers and past smokers now have a more accurate way of detecting whether or not they have lung cancer thanks to a comprehensive lung cancer screening program that uses CT scan technology at Intermountain Medical Center in Salt Lake City.

Contact: Jess C. Gomez
Intermountain Medical Center

Public Release: 8-Jul-2015
UK study reveals new method to develop more efficient drugs
A new study led by University of Kentucky researchers suggests a new approach to develop highly potent drugs which could overcome current shortcomings of low drug efficacy and multi-drug resistance in the treatment of cancer as well as viral and bacterial infections.

Contact: Allison Perry
University of Kentucky

Public Release: 8-Jul-2015
Treating breast cancer with progesterone could aid survival
A special technique where breast cancer cells are 'rescued' for research has been developed at the University of Adelaide. Coupled with advanced scientific technologies pioneered by Cambridge University this has provided a unique insight into the hormone regulation of breast cancers, which is expected to lead to new treatments for the disease.
Cancer Research UK, European Research Council, National Health and Medical Research Council of Australia, Cancer Australia, National Breast Cancer Foundation

Contact: Wayne Tilley
University of Adelaide

Public Release: 8-Jul-2015
Study estimates number of deaths attributed to low levels of education
A new study by researchers at the University of Colorado, New York University, and the University of North Carolina at Chapel Hill estimates the number of deaths that can be linked to differences in education, and finds that variation in the risk of death across education levels has widened considerably.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development

Contact: Rachel Harrison
New York University

Public Release: 8-Jul-2015
Proceedings of the National Academy of Sciences
Hybrid cells cause chaos around cancers
Rice University researchers have built a simulation to understand how cancerous tumors manipulate blood-vessel growth.
National Science Foundation, Cancer Prevention and Research Institute of Texas, São Paulo Research Foundation, Tauber Family Funds, Maguy-Glass Chair in Physics of Complex Systems at Tel Aviv University

Contact: David Ruth
Rice University

Public Release: 8-Jul-2015
Disrupting cells' 'powerhouses' can lead to tumor growth, Penn study finds
A study by University of Pennsylvania researchers implicates defects in mitochondria, the energy-production centers of cells, as playing a key role in the transition from normal to cancerous.
National Institutes of Health, Harriet Ellison Woodward Trust

Contact: Katherine Unger Baillie
University of Pennsylvania

Public Release: 8-Jul-2015
Journal of Hepatology
Research links intrahepatic cholestasis of pregnancy with liver cancer and other diseases later in life
In a new study of more than 125,000 pregnant women in Sweden, researchers found that the risk of hepatobiliary cancer and immune-mediated and cardiovascular diseases later in life is higher in women with intrahepatic cholestasis of pregnancy than in women without this condition. Their results are published in the Journal of Hepatology.

Contact: Sybrand Boer Iwema
Elsevier Health Sciences

Public Release: 8-Jul-2015
European Journal of Immunology
Lymphoma: How the tumor escapes the immune response
Natural killer cells of the immune system can fend off malignant lymphoma cells and thus are considered a promising therapeutic approach. However, in the direct vicinity of the tumor they lose their effect. Scientists of Helmholtz Zentrum München have now elucidated which mechanisms block the natural killer cells and how this blockade could be lifted. The results were recently published in the European Journal of Immunology.
Wilhelm Sander-Stiftung

Contact: Dr. Ralph Mocikat
Helmholtz Zentrum München - German Research Center for Environmental Health

Public Release: 8-Jul-2015
Common hormone could help treat breast cancer
Around half of all breast cancer patients could one day benefit from having the cheap and widely-available female hormone progesterone added to their treatment, according to Cancer Research UK funded research published in Nature.
Cancer Research UK

Contact: Ailsa Stevens
Cancer Research UK

Public Release: 7-Jul-2015
Cell Reports
Two are better than one -- another checkpoint enzyme for flawless cell division
The error-free distribution of genetic material during cell division is important for preventing the development of tumor cells. Professor Erich Nigg's research group at the Biozentrum, University of Basel, has uncovered a new important function of the human enzyme Plk1. It plays a significant role in monitoring chromosome segregation. The results published in the journal Cell Reports may provide important clues for the treatment of cancer.

Contact: Olivia Poisson
University of Basel

Public Release: 7-Jul-2015
Proceedings of the National Academy of Sciences
Cancer drug 49 times more potent than Cisplatin
Tests have shown that a new cancer drug, FY26, is 49 times more potent than the clinically used treatment Cisplatin. Based on a compound of the rare precious metal osmium and developed by researchers at the University of Warwick's Department of Chemistry and the Warwick Cancer Research Unit, FY26 is able to shut down a cancer cell by exploiting weaknesses inherent in their energy generation.
Biotechnology and Biological Sciences Research Council, European Research Council, Wellcome Trust, European Union

Contact: Tom Frew
University of Warwick

Public Release: 7-Jul-2015
USC cancer researchers ID potential treatment for deadly lymphoma
New research from the USC Norris Comprehensive Cancer Center has identified a potential treatment for a rare but previously incurable form of lymphoma that is observed primarily in patients with HIV/AIDS infection.
National Institutes of Health, Southern California Clinical and Translational Science Institute, Stop Cancer Foundation

Contact: Alison Trinidad
University of Southern California - Health Sciences

Public Release: 7-Jul-2015
Practical Radiation Oncology
Extended-field IMRT does not increase duodenal toxicity risk
A study of women with cervical or endometrial cancer who require treatment to the para-aortic (PA) lymph nodes can safely receive extended-field intensity modulated radiation therapy without increased risk of duodenal toxicity, according to a study published in the July-August 2015 issue of Practical Radiation Oncology, the American Society for Radiation Oncology's journal focused on the clinical practice of radiation oncology.

Contact: Michelle Kirkwood
American Society for Radiation Oncology

Public Release: 7-Jul-2015
Journal of Immunotherapy
Investigators develop activated T cell therapy for advanced melanoma
T cells from patients with melanoma can trigger a protective immune response against the disease according to a new study out of University Hospitals Case Medical Center Seidman Cancer Center and Case Western Reserve University School of Medicine. Published in the July/August issue of Journal of Immunotherapy, these new findings demonstrate that T cells derived from lymph nodes of patients with melanoma can be expanded in number and activated in the laboratory for intravenous administration in the treatment of patients.

Contact: Alicia Reale
University Hospitals Case Medical Center

Showing releases 976-1000 out of 1299.

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