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Bioinformatics

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Key: Meeting M      Journal J      Funder F

Showing releases 126-150 out of 816.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 > >>

Public Release: 4-May-2015
Nature Medicine
Study points to possible treatment for lethal pediatric brain cancer
Using brain tumor samples collected from children in the United States and Europe, an international team of scientists found that the drug panobinostat and similar gene regulating drugs may be effective at treating diffuse intrinsic pontine gliomas, an aggressive and lethal form of pediatric cancer.
National Institutes of Health, DIPG Collaborative, Cure Starts Now Foundation, Reflections of Grace Foundation, Smiles for Sophie Foundation, Cancer-Free Kids Foundation, Carly's Crusade Foundation and others

Contact: Christopher G. Thomas
thomaschr@ninds.nih.gov
30-149-657-511
NIH/National Institute of Neurological Disorders and Stroke

Public Release: 4-May-2015
Nature Genetics
Joining the genomic dots
Researchers have developed and used a new technique to join the dots in the genomic puzzle. Just as dot to dot puzzles needs to be completed to visualize the full picture, the researchers' analysis connected regulatory elements called promoters and enhancers and showed their physical interactions over long distances within the mouse and human genomes. The ability to map these interactions in the human genome has huge potential in understanding the genetic basis of disease.
Biotechnology and Biological Science Research Council, Medical Research Council, Leukaemia & Lymphoma Research, European Commission

Contact: Babraham Institute KEC Team
kec@babraham.ac.uk
44-012-234-96230
Babraham Institute

Public Release: 4-May-2015
Nature Genetics
Decoding DNA's phonebook
A high-res genome catalog captures long-distance calls between DNA segments that may influence diseases.
Leukaemia and Lymphoma Research Fellowship, Framework Programme 7 Epigenesys Network of Excellence, Cancer Research UK, University College London, Okinawa Institute of Science and Technology, Wellcome Trust

Contact: Kaoru Natori
kaoru.natori@oist.jp
81-989-662-389
Okinawa Institute of Science and Technology (OIST) Graduate University

Public Release: 1-May-2015
Neuro-Oncology
TGen-UCSF study in Neuro-Oncology provides comprehensive look at brain cancer treatments
Led by TGen and UCSF, a comprehensive genetic review of treatment strategies for glioblastoma brain tumors was published today in the Oxford University Press journal Neuro-Oncology. The study, 'Towards Precision Medicine in Glioblastoma: The Promise and The Challenges,' covers how these highly invasive and almost-always-deadly brain cancers may be treated, reviews the continuing challenges faced by researchers and clinicians, and presents the hope for better treatments by harnessing the power of the human genome.
Ben & Catherine Ivy Foundation

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute

Public Release: 1-May-2015
Frontiers in Ecology and the Environment
Citizen science helps predict risk of emerging infectious disease
More than 1,600 trained citizen scientists boosted the reach and accuracy of a long-term geographic mapping project to predict the spread of sudden oak death, an infectious disease that's killed millions of trees in California and Oregon. Results showed that trained volunteers were just as reliable in collecting data as professionals, resulting in accurate computer models for predicting the plant disease's spread.
National Science Foundation, US Forest Service, Gordon and Betty Moore Foundation

Contact: Ross Meentemeyer
rkmeente@ncsu.edu
919-513-2372
North Carolina State University

Public Release: 30-Apr-2015
Applications in Plant Sciences
MarkerMiner 1.0: An easy-to-use bioinformatics platform for DNA analysis in angiosperms
Researchers have developed MarkerMiner, a new software that simplifies analysis of next-generation sequencing data in angiosperms. MarkerMiner is an automated, open-source, bioinformatics workflow that aids plant researchers in the discovery of single-copy nuclear genes. The software (published in Applications in Plant Sciences) is easy to use, offers a multipurpose, configurable output, and is accessible to users with limited bioinformatics training or without access to computing resources.
National Science Foundation

Contact: Beth Parada
apps@botany.org
Botanical Society of America

Public Release: 29-Apr-2015
CLEO 2015
A phone with the ultimate macro feature
Researchers at the University of California, Los Angeles have recently developed a device that can turn any smartphone into a DNA-scanning fluorescent microscope.

Contact: Rebecca B. Andersen
RAndersen@osa.org
202-416-1443
The Optical Society

Public Release: 29-Apr-2015
PLOS Computational Biology
New Big Data era pushes training need for bioinformatics in life sciences
In the advent of big data, the requirement for bioinformatics training as an integral part in life science research is becoming increasingly apparent. For the first time, an international consortium of bioinformatics educators and trainers across the globe have come together to transcend institutional and international boundaries to share bioinformatics training expertise, experience, and resources.
Global Organisation for Bioinformatics Learning, Education & Training

Contact: Hayley London
hayley.london@tgac.ac.uk
01-603-450-107
The Genome Analysis Centre

Public Release: 28-Apr-2015
Chemotargets launches easier-to-use, more intuitive graphical interface CTlink[GUI]
Chemotargets, a spin-off company of IMIM, has launched CTlink[GUI] -- a commercial version of the CTlink software that offers users intuitive, interactive graphical tools enabling them to more easily analyze results obtained using this software. CTlink is software that can be installed on any type of computer and predicts how small molecules will interact with certain proteins; it is a key tool for biotechnology and pharmaceutical companies.

Contact: Marta Calsina
mcalsina@imim.es
34-933-160-680
IMIM (Hospital del Mar Medical Research Institute)

Public Release: 27-Apr-2015
Genome Biology
Bumblebee genome mapped
A research collaboration spearheaded by ETH Zurich has shed light on the genome of two commercially important species of bumblebees. The findings provide unexpected insights into the ecology and evolution of bumblebees and honeybees.

Contact: Paul Schmid-Hempel
paul.schmid-hempel@env.ethz.ch
41-446-336-048
ETH Zurich

Public Release: 27-Apr-2015
Nucleic Acids Research
New 3-D method improves the study of proteins
Researchers from the Institute of Biotechnology and Biomedicine at the Universitat Autònoma de Barcelona and from the University of Warsaw have developed a new computational method called AGGRESCAN3D which will allow studying in 3-D the structure of folded globular proteins and substantially improve the prediction of any propensity for forming toxic protein aggregates. Proteins can also be modeled to study the pathogenic effects of the aggregation or redesign them for therapeutic means.

Contact: Maria Jesus Delgado
MariaJesus.Delgado@uab.cat
34-935-814-049
Universitat Autonoma de Barcelona

Public Release: 27-Apr-2015
Nature Genetics
Olga Troyanskaya brings order to big data of human biology
Combining genomic data from 38,000 experiments, plus relevant GWASs, this group has generated functional genetic maps for 144 human tissues types and organs. This big step in the use of large genomic data sets enables great strides in functional human genetics, with important applications for treatment of disease.

Contact: Anastasia Greenebaum
agreenebaum@simonsfoundation.org
212-524-6097
Simons Foundation

Public Release: 27-Apr-2015
Nature Genetics
Researchers train computers to identify gene interactions in human tissues
Dartmouth researchers and their collaborators have trained a computer to crunch big biomedical data in order to recognize how genes work together in human tissues.

Contact: John Cramer
john.cramer@dartmouth.edu
603-646-9130
Dartmouth College

Public Release: 24-Apr-2015
Genome Research
Systematic interaction network filtering in biobanks
While seeking targets to attack Huntington's disease, an incurable inherited neurodegenerative disorder, neurobiologists of the research group led by Professor Erich Wanker of the Max Delbrück Center found what they were looking for. Using a filtering strategy borrowed from criminologists, the researchers systematically filtered interaction networks of various biological databases until they ultimately found a protein with protective function.
Deutsche Forschungsgemeinschaft, Federal Ministry of Education and Research, Helmholtz Association

Contact: Barbara Bachtler
bachtler@mdc-berlin.de
49-309-406-3896
Max Delbrück Center for Molecular Medicine in the Helmholtz Association

Public Release: 23-Apr-2015
Proceedings of the National Academy of Sciences
A focus on flight
A new study shows birds use two highly stereotyped postures to avoid obstacles in flight. The study could open the door to new ways to program drones and other unmanned aerial vehicles to avoid similar obstacles.

Contact: Peter Reuell
preuell@fas.harvard.edu
617-496-8070
Harvard University

Public Release: 23-Apr-2015
Genome Research
Novel regulator inhibits toxic protein aggregates in Huntington's disease
Huntington's disease is a neurodegenerative disorder characterized by huntingtin protein aggregates in a patient's brain, but how these aggregates form is not well understood. In a study published online today in Genome Research, researchers developed a novel computational strategy to identify interaction partners of the huntingtin protein and discovered a novel factor that suppresses misfolding and aggregation.
Deutsche Forschungsgemeinschaft, German Federal Ministry of Education and Research, HDSA Coalition for the Cure, European Union, Helmholtz Association

Contact: Peggy Calicchia
calicchi@cshl.edu
516-422-4012
Cold Spring Harbor Laboratory

Public Release: 21-Apr-2015
28th Fungal Genetics Conference
Fourteen early career researchers receive awards at fungal genetics conference
The Genetics Society of America (GSA) and the community of fungal geneticists are pleased to announce the winners of the GSA poster awards at the 28th Fungal Genetics Conference, which took place in Pacific Grove, Calif., March 17-22, 2015. The awards were made to graduate student and postdoctoral scientists in recognition of the research they presented at the conference.
Genetics Society of America

Contact: Adam Fagen
afagen@genetics-gsa.org
Genetics Society of America

Public Release: 21-Apr-2015
Current Biology
Why some neurons 'outsource' their cell body
Nerve cells come in very different shapes. Researchers at the Bernstein Center Berlin now reveal why, in insects, the cell body is usually located at the end of a separate extension. Using mathematical models, they show that this increases the strength of electrical signal transmission at no additional energetic cost.
Federal Ministry of Education and Research Germany, Deutsche Forschungsgemeinschaft

Contact: Mareike Kardinal
mareike.kardinal@bcos.uni-freiburg.de
49-076-120-39593
Bernstein Coordination Site (BCOS)

Public Release: 20-Apr-2015
PLOS Computational Biology
New tactic targets brain tumors
Patients who are obese, diabetic or both have the highest incidence of brain tumors, and they offer a clue that insulin is a factor for some glioblastoma patients. But a new Rice University study suggests drugs tested on such tumors targeted the wrong molecules.
National Science Foundation

Contact: David Ruth
david@rice.edu
713-348-6327
Rice University

Public Release: 20-Apr-2015
Conference on Human Factors in Computing Systems (CHI 2015)
Technology can transfer human emotions to your palm through air, say scientists
Human emotion can be transferred by technology that stimulates different parts of the hand without making physical contact with your body, a University of Sussex-led study has shown.
European Research Council

Contact: James Hakner
press@sussex.ac.uk
44-127-367-8888
University of Sussex

Public Release: 18-Apr-2015
American Association for Cancer Research Annual Meeting 2015
Study reveals a cause of poorer outcomes for African-American patients with breast cancer
Poorer outcomes for African-American women with estrogen-receptor positive breast cancer, compared with European-American patients, appears to be due, in part, to a strong survival mechanism within the cancer cells, according to a study.
Nina Hyde Center for Breast Cancer Research

Contact: Karen Teber
km463@georgetown.edu
Georgetown University Medical Center

Public Release: 16-Apr-2015
Bioinformatics
Novel online bioinformatics tool significantly reduces time of multiple genome analysis
A UK research collaboration developed a new bioinformatics pipeline that enables automated primer design for multiple genome species, significantly reducing turnaround time.

Contact: Hayley London
hayley.london@tgac.ac.uk
44-160-345-0107
The Genome Analysis Centre

Public Release: 16-Apr-2015
Molecular Systems Biology
Systems-wide genetic study of blood pressure regulation in the Framingham Heart Study
A genetic investigation of individuals in the Framingham Heart Study may prove useful to identify novel targets for the prevention or treatment of high blood pressure. The study, which takes a close look at networks of blood pressure-related genes, is published in the journal Molecular Systems Biology.

Contact: Barry Whyte
barry.whyte@embo.org
EMBO

Public Release: 15-Apr-2015
International Journal of Epidemiology
Paternal sperm may hold clues to autism
In a small study, Johns Hopkins researchers found that DNA from the sperm of men whose children had early signs of autism shows distinct patterns of regulatory tags that could contribute to the condition.
NIH/National Institute of Environmental Health Sciences, Autism Speaks

Contact: Catherine Kolf
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine

Public Release: 15-Apr-2015
PLOS ONE
New method increases accuracy of ovarian cancer prognosis and diagnosis
University of Utah scientists have uncovered patterns of DNA anomalies that predict a woman's outcome significantly better than tumor stage. In addition, these patterns are the first known indicator of how well a woman will respond to platinum therapy. Published in the journal PLOS ONE, the patterns were discovered by using a new mathematical technique in the analysis of DNA profiles from the Cancer Genome Atlas, a national database containing data from hundreds of ovarian cancer patients.
Utah Science, Technology, and Research Initiative, NIH/National Human Genome Research Institute, National Science Foundation

Contact: Julie Kiefer
jkiefer@neuro.utah.edu
801-597-4258
University of Utah Health Sciences

Showing releases 126-150 out of 816.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 > >>