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Key: Meeting M      Journal J      Funder F

Showing releases 176-200 out of 817.

<< < 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 > >>

Public Release: 16-Mar-2015
American Journal of Epidemiology
Genetics: No evidence of role in racial mortality gap
There is still no evidence of genetic difference between blacks and whites to account for the health disparities in cardiovascular disease, according to a new study by McGill University researchers. Published in the American Journal of Epidemiology, the researchers suggest that after a decade of genetic studies, factors such as lifestyle, education and socio-economics -- not genetics -- are more promising avenues to understanding racial health disparities.

Contact: Cynthia Lee
cynthia.lee@mcgill.ca
514-398-6754
McGill University

Public Release: 16-Mar-2015
Nature Communications
Penn vet team points to new colon cancer culprit
Colon cancer is a heavily studied disease -- and for good reason. It is one of the leading causes of cancer-related deaths worldwide, and its numbers are on the rise, from 500,000 deaths in 1990 to 700,000 in 2010. This growth comes despite scientists' ever-increasing knowledge of the genetic mutations that initiate and drive this disease. Now, a team of researchers from the University of Pennsylvania has found evidence of a new culprit in the disease, a protein called MSI2.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, NIH/National Cancer Institute

Contact: Katherine Unger Baillie
kbaillie@upenn.edu
215-898-9194
University of Pennsylvania

Public Release: 16-Mar-2015
PLOS Computational Biology
New possibilities for the treatment of breast cancer arise, with the help of mathematics
Researchers of three of Switzerland's leading scientific institutions have brought to light a means of reprogramming a flawed immune response into an efficient anti-tumoral one by the results of a translational trial relating to breast cancer. Thanks to the innovative combination of mathematical modelization and experimentation, only 20 tests were necessary, whereas traditional experimentation would have required 596 tests to obtain the same results.

Contact: Ioannis Xenarios
Ioannis.Xenarios@isb-sib.ch
41-216-924-031
Swiss Institute of Bioinformatics

Public Release: 16-Mar-2015
BMC Psychiatry
Risk patterns identified that make people more vulnerable to PTSD
Researchers from NYU Langone Medical Center have built a new computational tool that identifies 800 different ways people are at increased risk for post-traumatic stress disorder, permitting for the first time a personalized prediction guide.
NIH/National Institute of Mental Health

Contact: Jim Mandler
jim.mandler@nyumc.org
212-404-3525
NYU Langone Medical Center / New York University School of Medicine

Public Release: 16-Mar-2015
Oncogene
When cancer cells stop acting like cancer
Cancer cells crowded tightly together suddenly surrender their desire to spread, and this change of heart is related to a cellular pathway that controls organ size.
National Institutes of Health

Contact: Karen Teber
km463@georgetown.edu
Georgetown University Medical Center

Public Release: 13-Mar-2015
Stem Cell Reports
OSKM stoichiometry determines iPS cell reprogramming
Researchers at Kyoto University's Center for iPS Cell Research and Application discover a simple way to increase the production of induced pluripotent stem cells. A major hurdle in reprogramming science is generating a sufficient number of iPS cells to conduct basic research experiments. Yet, a report published in Stem Cell Reports shows that simply adding 9 amino acids to the induction transgene Klf4 dramatically elevates the production of fully reprogrammed mouse iPS cells.

Contact: Akemi Nakamura
media@cira.kyoto-u.ac.jp
81-753-667-005
Center for iPS Cell Research and Application - Kyoto University

Public Release: 11-Mar-2015
Molecular Systems Biology
Researchers develop tool to understand how the gut microbiome works
Researchers at Harvard Medical School and Columbia University in the United States have developed a way to study the functions of hard-to-grow bacteria that contribute to the composition of the gut microbiome.

Contact: Barry Whyte
barry.whyte@embo.org
EMBO

Public Release: 11-Mar-2015
Nature
Length matters
Mutations in the MECP2 gene are the cause of the devastating childhood neurological disorder Rett Syndrome. Despite intense efforts spanning several decades the precise function of MECP2 has been difficult to pin down. Research primarily funded by the Rett Syndrome Research Trust and NINDS, and published today in Nature reveals important information that could lead to new treatment approaches. The study, led by Michael Greenberg, Ph.D., Chairman of the Department of Neurobiology at Harvard University, shows that MECP2 dampens the expression of long genes.
Rett Syndrome Research Trust, NIH/National Institute of Neurological Disorders and Stroke, Damon Runyon Cancer Research Foundation, William Randolph Hearst, Howard Hughes Medical Institute, and others

Contact: Monica Coenraads
monica@rsrt.org
203-445-0041
Rett Syndrome Research Trust

Public Release: 9-Mar-2015
DNA and Cell Biology
Viagra in combination with new drugs can have anti-cancer, antibacterial, and therapeutic effects
Chaperone proteins play an important role in protein folding in human cells and in bacteria and are promising new targets for drugs to treat cancer and Alzheimer's disease and for novel antiviral drugs and antibiotics. How existing drugs such as Viagra or Cialis and a derivative of the drug Celebrex, for example, can reduce the activity of a specific chaperone protein, with the potential for anti-tumor and anti-Alzheimer's disease effects, is described in a Review article in DNA and Cell Biology.

Contact: Kathryn Ryan
kryan@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 9-Mar-2015
Nature Biotechnology
New technique can locate genes' on-off switches
Researchers at the Stowers Institute for Medical Research have developed a high-resolution method that can precisely and reliably map individual transcription factor binding sites in the genome, vastly outperforming standard techniques.
Stowers Institute for Medical Research, National Institutes of Health

Contact: Kim Bland
ksb@stowers.org
816-926-4015
Stowers Institute for Medical Research

Public Release: 3-Mar-2015
Molecular Biology and Evolution
Grand tree of life study shows a clock-like trend in new species emergence and diversity
Temple University researchers have assembled the largest and most accurate tree of life calibrated to time, and surprisingly, it reveals that life has been expanding at a constant rate. The study also challenges the conventional view of adaptation being the principal force driving species diversification, but rather, underscores the importance of random genetic events and geographic isolation in speciation, taking about 2 million years on average for a new species to emerge onto the scene.

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-258-8972
Molecular Biology and Evolution (Oxford University Press)

Public Release: 2-Mar-2015
Nature Cell Biology
Researchers discover 'milk' protein that enables survival of the species
Australian researchers have discovered the protein MCL-1 is critical for keeping milk-producing cells alive and sustaining milk production in the breast. Without milk production, offspring cannot survive, making MCL-1 essential for survival of mammalian species.
National Health and Medical Research Council, Australian Cancer Research Foundation, National Breast Cancer Foundation, Cure Cancer Australia Foundation, Victorian Government

Contact: Liz Williams
williams@wehi.edu.au
61-428-034-089
Walter and Eliza Hall Institute

Public Release: 27-Feb-2015
Enhancing studies on a possible blood biomarker for traumatic brain injury
New technology being introduced at NYU Langone Medical Center could help researchers advance blood biomarker capabilities that show changes in low concentrations of specific proteins present following a neurological injury.
The Steven & Alexandra Cohen Foundation

Contact: Jim Mandler
jim.mandler@nyumc.org
212-404-3525
NYU Langone Medical Center / New York University School of Medicine

Public Release: 27-Feb-2015
Modern Pathology
New breast cancer test links immune 'hotspots' to better survival
Scientists have developed a new test which can predict the survival chances of women with breast cancer by analyzing images of 'hotspots' where there has been a fierce immune reaction to a tumor. Researchers used statistical software previously used in criminology studies of crime hotspots to track the extent to which the immune system was homing in and attacking breast cancer cells.
Engineering and Physical Sciences Research Council, The Institute of Cancer Research, London

Contact: Claire Hastings
chastings@icr.ac.uk
020-715-35380
Institute of Cancer Research

Public Release: 26-Feb-2015
Applications in Plant Sciences
Better genes for better (more adaptable) beans
Out of thousands of legume species, only a few are used in mainstream agriculture. Among the underutilized legume species are crops that can tolerate poor soil with limited water. A new genetic resource identifying over 30,000 genes and nearly 3,000 genetic markers will help researchers link genetic sequences to traits found in legumes that thrive in harsh environmental conditions. This study, published in Applications in Plant Sciences, marks a new, valuable genetic resource for Fabaceae.
University of Southampton

Contact: Beth Parada
apps@botany.org
Botanical Society of America

Public Release: 25-Feb-2015
mBio
Sewage provides insight into human microbiome
A new study demonstrates that sewage is an effective means to sample the fecal bacteria from millions of people. Researchers say the information gleaned from the work provides a unique opportunity to monitor, through gut microbes, the public health of a large population without compromising the privacy of individuals.
National Institutes of Health

Contact: Gina Hebert
ghebert@mbl.edu
508-289-7725
Marine Biological Laboratory

Public Release: 24-Feb-2015
Clinical Cancer Research
TGen study: Destroying tumor material that 'cloaks' cancer cells could benefit patients
Like a stealth jet cloaks itself from radar, cancer cells cloak themselves within tumors by hiding behind a dense layer of cellular material known as stroma. According to a new study by the Translational Genomics Research Institute, drugs that target and strip away the stroma would pave the way for drugs to reach the cancerous cells within the tumor, which could have a beneficial effect on the survival of pancreatic cancer patients.
NIH/National Cancer Institute, Stand Up To Cancer, Katz Family Foundation, National Foundation for Cancer Research

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute

Public Release: 24-Feb-2015
UC Davis leads new effort in functional annotation of animal genomes
Scientists and breeders working with poultry and livestock species will get a new set of tools from an international project that includes the University of California, Davis. The University of California Davis team, led by functional genomicist Huaijun Zhou will focus on the genomes of the chicken, cow and pig, which make up the largest meat-producing industries in the United States. The broad international effort is called the Functional Annotation of Animal Genomes Initiative.
U.S. Department of Agriculture - National Institute of Food and Agriculture, the U.S. Poultry, Cattle and Swine Genomes Coordination Funds, the National Pork Board, Aviagen LTD

Contact: Patricia Bailey
pjbailey@ucdavis.edu
530-752-9843
University of California - Davis

Public Release: 24-Feb-2015
Nature Reviews Cancer
Scientists find cancer weak spots for new targeted drugs
Scientists have identified weak spots in cancer cells that could be targeted and attacked by new precision drugs.
Cancer Research UK

Contact: James Hakner
press@sussex.ac.uk
44-127-367-8888
University of Sussex

Public Release: 23-Feb-2015
Nature
'DNA spellchecker' means that our genes aren't all equally likely to mutate
A study that examined 17 million mutations in the genomes of 650 cancer patients concludes that large differences in mutation rates across the human genome are caused by the DNA repair machinery. 'DNA spellchecker' is preferentially directed towards more important parts of chromosomes that contain key genes. The study illustrates how data from medical sequencing projects can answer basic questions about how cells work.
Sanger Institute, Spanish Ministry of Economy and Competitiveness

Contact: Laia Cendrós
laia.cendros@crg.eu
34-607-611-798
Center for Genomic Regulation

Public Release: 22-Feb-2015
2015 IEEE International Solid State Circuits Conference
Fever alarm armband: A wearable, printable, temperature sensor
University of Tokyo researchers have developed a 'fever alarm armband,' a flexible, self-powered wearable device that sounds an alarm in case of high body temperature. This armband will be presented at the 2015 IEEE International Solid State Circuits Conference, San Francisco, on Feb. 22-26, 2015. The flexible organic components developed for this device are well-suited to wearable devices that continuously monitor vital signs including temperature and heart rate for applications in healthcare settings.
Japan Science and Technology Agency, Exploratory Research for Advanced Technology, JST ERATO Someya Bio-Harmonized Electronics Project

Contact: Takao Someya
someya@ee.t.u-tokyo.ac.jp
81-358-410-411
University of Tokyo

Public Release: 20-Feb-2015
Biopreservation and Biobanking
Future of biobanking and translational research in China
As clinical medical research in China reaches a turning point, the country's strategy for expanding its biosample collection and analysis capabilities and its focus on acquiring new sources of biomedical data to accelerate translational research are highlighted in a special issue of Biopreservation and Biobanking.

Contact: Kathryn Ryan
kryan@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 19-Feb-2015
Journal for Nurse Practitioners
Mobile app with evidence-based decision support diagnoses more obesity, smoking, and depression, Columbia Nursing study finds
Smartphones and tablets may hold the key to getting more nurses to diagnose patients with chronic health issues like obesity, smoking, and depression -- three of the leading causes of preventable death and disability.
NIH/National Institute for Nursing Research

Contact: Lisa Rapaport
lr2692@cumc.columbia.edu
212-342-3795
Columbia University Medical Center

Public Release: 19-Feb-2015
ACS Chemical Biology
The promiscuity of chemical probes discovered
Researchers at IMIM have applied a new computational methodology to anticipate the degree of selectivity of the molecules that are used to study protein functions and reduce the risk of establishing erroneous relations between proteins and diseases.The study has proven that many of these small molecules or chemical probes are not as selective as believed, but instead interact with multiple proteins, which could lead to confusion in experimental results.This is key to developing safer pharmaceuticals

Contact: Marta Calsina Freixas
mcalsina@imim.es
34-933-160-680
IMIM (Hospital del Mar Medical Research Institute)

Public Release: 19-Feb-2015
Science
New ALS gene and signaling pathways identified
Using advanced DNA sequencing methods, researchers have identified a new gene that is associated with sporadic amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease.
Biogen Idec, Wellcome Trust, Medical Research Council, MND Association, American ALS Association, National Institutes of Health, Angel Fund, Project ALS/P2ALS, ALS Therapy Alliance, Pierre L. de Bourghknecht ALS Research Foundation, and others

Contact: Karin Eskenazi
ket2116@columbia.edu
212-342-0508
Columbia University Medical Center

Showing releases 176-200 out of 817.

<< < 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 > >>