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Key: Meeting M      Journal J      Funder F

Showing releases 26-50 out of 840.

<< < 1 | 2 | 3 | 4 | 5 | 6 > >>

Public Release: 6-Nov-2015
Nature Communications
Neurodermatitis genes influence other allergies
There's a typical 'career' for some allergic people, and it starts very early on the skin: babies develop atopic dermatitis, food allergies may follow, then comes asthma and later on hay fever. A group of scientists led by Ingo Marenholz and Young-Ae Lee at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association, working with colleagues from several institutions, has now identified seven genetic risk loci for this course of disease.

Contact: Josef Zens
Max Delbrück Center for Molecular Medicine in the Helmholtz Association

Public Release: 5-Nov-2015
New from CSHLPress, an indispensable bench-side handbook for biologists using R
'Using R at the Bench: Step-by-Step Data Analytics for Biologists,' from Cold Spring Harbor Laboratory Press, is a convenient bench-side handbook for biologists, designed as a handy reference guide for elementary and intermediate statistical analyses using the free/public software package known as 'R.' It is both a simple refresher as well as an overview, and is available in both spiral bound hardcover and eBook formats.

Contact: Robert Redmond
Cold Spring Harbor Laboratory

Public Release: 4-Nov-2015
Science Translational Medicine
More than skin deep
Most products on the market today that are used to treat skin problems target the effects of the disease or wound such as inflammation, which can prolong the healing process and result in scarring. However, LSU Assistant Professor Wei Xu and collaborators at Northwestern University discovered a new way to prevent inflammation and to speed up the skin's healing process.

Contact: Alison Satake
Louisiana State University

Public Release: 4-Nov-2015
Nature Communications
'Liquid biopsy' promotes precision medicine by tracking patient's cancer
A team of researchers, including scientists from the Translational Genomics Research Institute (TGen), has reported that analyzing circulating tumor DNA (ctDNA) can track how a patient's cancer evolves and responds to treatment. In a study published today in Nature Communications, Dr. Muhammed Murtaza of TGen and Mayo Clinic, and colleagues, describe an extensive comparison between biopsy results and analysis of ctDNA in a patient with breast cancer.

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 3-Nov-2015
Grant establishes center for 3-D structure and physics of the genome at UMMS
The University of Massachusetts Medical School has been awarded a five-year, $15 million grant from the National Institutes of Medicine Common Fund to establish the Center for 3-D Structure and Physics of the Genome. The center is part of the NIH's 4-D Nucleome Program, an interdisciplinary effort comprising 29 research teams across the country with the goal of mapping the three-dimensional architecture of the human genome and how this organization changes over time -- the fourth dimension.
National Institutes of Medicine Common Fund, NIH/National Cancer Institute, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, NIH/National Institute of Biomedical Imaging and Bioengineering, NIH/National Heart, Lung and Blood Institute

Contact: Jim Fessenden
University of Massachusetts Medical School

Public Release: 3-Nov-2015
Chemical Research in Toxicology
New computational approach to predicting adverse drug reactions with higher confidence
A new integrated computational method helps predicting adverse drug reaction -- which are often lethal -- more reliably than with traditional computing methods. This improved ability to foresee the possible adverse effects of drugs may entail saving many lives in the future. The study is being conducted by researchers from IMIM (Hospital del Mar Medical Research Institute), University Pompeu Fabra, and the company Chemotargets, within the framework of the European eTOX project.

Contact: Marta Calsina Freixas
IMIM (Hospital del Mar Medical Research Institute)

Public Release: 2-Nov-2015
Nature Methods
Tissue cartography
Today's state-of-the-art optical microscopes produce voluminous three-dimensional data sets that are difficult to analyze. Now, two postdoctoral scholars from UC Santa Barbara's Kavli Institute for Theoretical Physics have developed a means of reducing data size and processing by orders of magnitude.

Contact: Julie Cohen
University of California - Santa Barbara

Public Release: 30-Oct-2015
New computational strategy finds brain tumor-shrinking molecules
Patients with glioblastoma, a type of malignant brain tumor, usually survive fewer than 15 months following diagnosis. Since there are no effective treatments for the deadly disease, University of California, San Diego researchers developed a new computational strategy to search for molecules that could be developed into glioblastoma drugs. In mouse models of human glioblastoma, one molecule they found shrank the average tumor size by half. The study is published October 30 by Oncotarget.
NIH/National Institutes of Health, Voices Against Brain Cancer Foundation, Christopher and Bronwen Gleeson Family Trust, American Brain Tumor Association Drug Discovery Grant

Contact: Heather Buschman
University of California - San Diego

Public Release: 30-Oct-2015
Nucleic Acids Research
Genetics of cancer cells: Computational models to sort out the chaos
Scientists of the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg have developed a method for analysing the genome of cancer cells more precisely than ever before. The team led by Prof. Antonio del Sol, head of the research group Computational Biology, is employing bioinformatics: Using novel computing processes, the researchers have created models of the genome of cancer cells based on known changes to the genome. These models are useful for determining the structure of DNA in tumors

Contact: Sabine Mosch
University of Luxembourg

Public Release: 29-Oct-2015
UC San Diego unveils campus-wide microbiome and microbial sciences initiative
University of California, San Diego Chancellor Pradeep K. Khosla announces the launch of the UC San Diego Microbiome and Microbial Sciences Initiative, a concerted research and education effort that leverages the university's strengths in science, medicine, engineering and the humanities to produce a detailed understanding of microbiomes -- distinct constellations of bacteria, viruses and other microorganisms that live within and around us -- and methods for manipulating them for the benefit of human health and the environment.

Contact: Heather Buschman
University of California - San Diego

Public Release: 29-Oct-2015
Streamlined import of specimen & occurrence records into taxonomic manuscripts
Substantial amount of documented occurrence (specimen and observational) records is awaiting publication stored in repositories and data indexing platforms, such as GBIF, BOLD systems, and iDigBio. In order to streamline the authoring process, save taxonomists time, and provide a workflow for peer-review and quality checks, Pensoft has introduced an innovative feature that makes it possible to easily import occurrence records into a taxonomic manuscript.

Contact: Lyubomir Penev
Pensoft Publishers

Public Release: 29-Oct-2015
Space station investigation goes with the flow
The investigation's success could help scientists develop countermeasures that will influence the future of human spaceflight on long-duration missions.

Contact: Rachel Hobson
NASA/Johnson Space Center

Public Release: 29-Oct-2015
PLOS Computational Biology
'Ensemble' modeling could lead to better flu forecasts
By combining data from a variety of non-traditional sources, a research team led by computational epidemiologists at Boston Children's Hospital has developed predictive models of flu-like activity that provide robust real-time estimates (a.k.a. 'now-casts') of flu activity and accurate forecasts of flu-like illness levels up to three weeks into the future.

Contact: Mauricio Santillana

Public Release: 28-Oct-2015
Hot processor speeds up UK genome analysis
The Genome Analysis Centre is the first Institute in the UK to deploy a new bioinformatics processor called DRAGEN, which dramatically reduces genomic pipeline run times from hours to minutes. This collaboration between Edico Genome and TGAC resulted in the first adaptation of the DRAGEN technology for the analysis of non-human genomes as part of the Institute's endeavors to sequence the DNA of plant, animal and microbial species to promote a sustainable bioeconomy.

Contact: Hayley London
The Genome Analysis Centre

Public Release: 26-Oct-2015
Proceedings of the National Academy of Sciences
CRISPR/Cas9 used for rapid functional study of cancer-causing genes
A novel approach using the recently developed CRISP/Cas9 technique to switch off genes has been used for the first time to identify genes that cause liver cancer in adult mice. Rapid, scalable and flexible, this new method can identify novel cancer-causing genes, determine which combinations cause cancer and model development of cancer in adults. The team show that CRISPR/Cas9 can be used to induce and study liver cancer, the sixth most prevalent cancer worldwide.
German Cancer Consortium, Helmholtz Gemeinschaft

Contact: Samantha Wynne
Wellcome Trust Sanger Institute

Public Release: 26-Oct-2015
Twenty-three researchers recognized as EMBO Young Investigators
EMBO announced today the selection of 23 young researchers as EMBO Young Investigators. The scientists join a network of 365 current and past Young Investigators who represent some of the best young group leaders contributing to research in Europe and beyond.
European Molecular Biology Organization

Contact: Yvonne Kaul

Public Release: 26-Oct-2015
FDA approves new therapy for pancreatic cancer patients
Patients with advanced pancreatic cancer now have access to the new FDA approved drug, Onivyde, that produced significant overall survival rates in an international clinical study conducted in part by researchers at HonorHealth Research Institute and the Translational Genomics Research Institute.

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 23-Oct-2015
Proceedings of the National Academy of Sciences
A new algorithm to predict the dynamic language of proteins
Researchers have developed the first computational method based on evolutionary principles to predict the changes in shape that proteins experience to carry out their functions. This method is a step forward in the study of protein dynamics, of great importance for the design of drugs and the investigation of genetic diseases such as cancer. The work, published in the journal Proceedings of the National Academy of Sciences, was prepared by researchers at the CNIO and University College London.

Contact: Vanessa Pombo
Centro Nacional de Investigaciones Oncologicas (CNIO)

Public Release: 22-Oct-2015
The ties that bind: WPI researchers search for the hidden genetic code across species
When species as different as humans and yeast share common genetic elements, those snippets of DNA are likely to perform fundamental biological functions. The National Science Foundation has awarded Worcester Polytechnic Institute $768,000 to identify such elements across all known genomes of plants, animals, fungi, and other complex organisms to gain insight into the roles they play. A team led by Dmitry Korkin will conduct the search using mathematical algorithms and advanced computing technology.
National Science Foundation

Contact: Michael Cohen
Worcester Polytechnic Institute

Public Release: 22-Oct-2015
Acta Diabetologica
Simple test to detect diabetes risk after pregnancy
Gestational diabetes is one of the most common conditions that can occur during pregnancy. Although the symptoms generally disappear after delivery, women suffering from gestational diabetes are at increased risk of developing postpartum diabetes in the following years. Researchers at the Helmholtz Zentrum München have now developed an accurate method of predicting the probability of developing this progressive disease following childbirth. Their findings were published recently in 'Acta Diabetologica.'

Contact: Prof. Dr. Anette-Gabriele Ziegler
Helmholtz Zentrum München - German Research Center for Environmental Health

Public Release: 22-Oct-2015
New gene a key to fighting sepsis
Scientists have identified a gene that could potentially open the door for the development of new treatments of the lethal disease sepsis.

Contact: Professor Simon Foote
Australian National University

Public Release: 21-Oct-2015
The Auk: Ornithological Advances
Advances in genetic studies of birds are changing ornithology research
How do birds evolve over generations? How do different bird populations diverge into new species? Ornithologists have been asking these questions since the days of Darwin, but rapid advances in genetic sequencing techniques in the last few years have brought answers more in reach than ever.

Contact: Rebecca Heisman
Central Ornithology Publication Office

Public Release: 20-Oct-2015
Molecular Cell
A new way to starve lung cancer?
Scientists have identified a new way to stop the growth of lung cancer cells, by blocking their ability to use alternative sources of nutrition. The discovery was made possible by identifying the metabolic programs used by cancer cells to fuel their growth. The findings point to possible new avenues for treating lung cancer, which is the second most common cancer and accounts for over one-quarter of all cancer-related deaths. The results of the study were published Oct. 15 in the journal Molecular Cell.

Contact: Cynthia Lee
McGill University

Public Release: 19-Oct-2015
Site of inflammatory bowel disease crucial
A groundbreaking study of more than 30,000 patients with inflammatory bowel disease has shown that genetic factors affect the location of the inflammation in the gut, with important implications for diagnosis and treatment of patients. The largest study of its kind, this research uncovered a genetic similarity between Crohn's disease and ulcerative colitis, suggesting they form a continuum of subtypes in the bowel. That genetic information could be used to inform treatment and reveal misdiagnoses.
National Association for Colitis and Crohn's disease, Wellcome Trust, Medical Research Council, Catherine McEwan Foundation, Peninsula College of Medicine and Dentistry, National Institute for Health Research, and others

Contact: Sam Wynne
Wellcome Trust Sanger Institute

Public Release: 19-Oct-2015
Proceedings of the National Academy of Sciences
Regrow a tooth? Fish -- yes; humans -- maybe some day
When a Lake Malawi cichlid loses a tooth, a new one drops neatly into place as a replacement. Why can't humans similarly regrow teeth lost to injury or disease?
NIH/National Institute of Dental and Craniofacial Research

Contact: John Toon
Georgia Institute of Technology

Showing releases 26-50 out of 840.

<< < 1 | 2 | 3 | 4 | 5 | 6 > >>