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Key: Meeting M      Journal J      Funder F

Showing releases 26-50 out of 828.

<< < 1 | 2 | 3 | 4 | 5 | 6 > >>

Public Release: 10-Aug-2015
Nature Genetics
New computational method predicts genes likely to be causal in disease
A new computational method improves the detection of genes that are likely to be causal for complex diseases and biological traits. The method, PrediXcan, estimates gene expression levels across the whole genome -- a better measure of biological action than single mutations -- and integrates it with genome-wide association study data. PrediXcan has the potential to identify gene targets for therapeutic applications faster and with greater accuracy than traditional methods.
National Institutes of Health

Contact: Kevin Jiang
kevin.jiang@uchospitals.edu
773-795-5227
University of Chicago Medical Center

Public Release: 10-Aug-2015
Nature Biotechnology
Life is but a DREAM
Can we use computers to predict whether a compound will have a toxic effect on people? The DREAM challenge uses crowdsourcing to test the state of the art.

Contact: Sonia Furtado-Neves
sonia.furtado@embl.de
European Molecular Biology Laboratory

Public Release: 7-Aug-2015
PLOS Biology
Studying yeast provides new insight to genome evolution
Researchers at the Centre for Genomic Regulation have proposed a new theory about the origins of the yeast lineage 100 million years ago. By studying the whole-genome duplication in yeast, the scientists have determined that it actually represents a hybrid between two distinct species. Their new proposal differs radically from the currently accepted theories within the scientific community.
European Research Council/European Union's Seventh Framework Programme, European Research Council, Spanish ministry of Economy and Competitiveness, Qatar National Research Fund

Contact: Laia Cendrós
laia.cendros@crg.eu
34-607-611-798
Center for Genomic Regulation

Public Release: 7-Aug-2015
Cell
Scientists adopt new strategy to find Huntington's disease therapies
Scientists searched the chromosomes of more than 4,000 Huntington's disease patients and found that DNA repair genes may determine when the neurological symptoms begin. The results may provide a guide for discovering new treatments for Huntington's disease and a roadmap for studying other neurological disorders.
National Institutes of Health, Medical Research Council, CHDI Foundation

Contact: Christopher G. Thomas
nindspressteam@ninds.nih.gov
301-496-5751
NIH/National Institute of Neurological Disorders and Stroke

Public Release: 7-Aug-2015
Basel Life Science Week 2015
Anti-aging researchers develop new algorithm that provides precision medicine for cancer patients
A targeted drug therapy avoids many of the negative side effects of traditional chemotherapy because it more specifically targets tumor cells. However, it has been limited in its effectiveness because it needs to be tailored to each individual patient. InSilico Medicine, Inc. has developed an algorithm to more effectively gauge what targeted drugs work on which patient. This algorithm will be presented at Basel Life Science Week 2015.

Contact: Qingsong Zhu
zhu@insilicomedicine.com
443-451-7212
InSilico Medicine, Inc.

Public Release: 6-Aug-2015
Stem Cells and Development
Protein identified that favors neuroprotective glial cell formation from stem cells
An international team of researchers has shown that NFIX, a protein that regulates neuronal stem cell activity (NSC), also has a role in driving NSC differentiation toward oligodendrocytes, a type of glial cell. These cells produce the myelin that surrounds and protects neurons. Evidence supporting this mechanism in mice and its potential in the development of NSC-based therapy for brain injury, demyelinating diseases, and brain tumors are discussed in a study published in Stem Cells and Development.

Contact: Kathryn Ryan
kryan@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 6-Aug-2015
Diabetes Care
Diabetes drug modulates cholesterol levels
Besides affecting the blood sugar levels, the substance Metformin, also has an impact on blood fat levels. This was elucidated by an interdisciplinary team of the German Center for Diabetes Research (DZD) headed by Dr. Rui Wang-Sattler of the Helmholtz Zentrum München. Especially the harmful LDL cholesterol can be reduced. The results have recently been published in the journal 'Diabetes Care.'

Contact: Dr. Rui Wang-Sattler
rui.wang-sattler@helmholtz-muenchen.de
49-893-187-3978
Helmholtz Zentrum München - German Research Center for Environmental Health

Public Release: 4-Aug-2015
Journal of Marketing Research
How to trust what your customers say about your brand
Marketers would love to get inside the consumer brain. And now they can. Researchers at UC Berkeley's Haas School of Business are using functional magnetic resonance imaging (fMRI) to see if what people say about brands matches what they are actually thinking.

Contact: Pamela Tom
ptom@berkeley.edu
510-642-2734
University of California - Berkeley Haas School of Business

Public Release: 3-Aug-2015
Technology
BioLEGO
This study introduces a freely available web-based application, BioLEGO, which provides access to computer-assisted single and two-step multiorganism fermentation process design.

Contact: Philly Lim
mllim@wspc.com
65-646-65775
World Scientific

Public Release: 3-Aug-2015
California Initiative to Advance Precision Medicine announces first project awards
Two projects have been selected by the California Initiative to Advance Precision Medicine, a public-private effort launched by Governor Edmund G. Brown, Jr. One will harness big data bioinformatics to help doctors identify effective treatments for California children with cancer who fail to respond to standard therapies. The other will enable detection of all known pathogens with a single DNA sequencing test, to diagnose acute infections in hospitalized patients.
California Initiative to Advance Precision Medicine

Contact: Laura Kurtzman
Laura.Kurtzman@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 3-Aug-2015
Nature Methods
New method reveals hidden population of regulatory molecules in cells
A recently discovered family of small RNA molecules, some of which have been implicated in cancer progression, has just gotten much larger thanks to a new RNA sequencing technique enabling sensitive detection of small RNAs that are chemically modified (methylated) after being transcribed from the genome. The researchers used the technique to reveal an abundance of modified fragments derived from transfer RNA molecules in both yeast cells and human cells.
National Institutes of Health

Contact: Tim Stephens
stephens@ucsc.edu
831-459-4352
University of California - Santa Cruz

Public Release: 31-Jul-2015
Nature Communications
RNA-binding protein influences key mediator of cellular inflammation and stress responses
RNA-binding proteins such as RC3H1 regulate the degradation of the mRNA molecules and thus prevent the production of specific proteins. Researchers at the Max Delbrück Center have now shown that ROQUIN binds several thousand mRNA molecules. They demonstrated that ROQUIN also influences the gene regulator NF-kappaB, a key mediator of cellular inflammation and stress responses.
Federal Ministry for Education and Research, Germany; Senate of Berlin, Berlin, Germany; Deutscher Akademischer Austauschdienst

Contact: Barbara Bachtler
bachtler@mdc-berlin.de
49-030-940-63896
Max Delbrück Center for Molecular Medicine in the Helmholtz Association

Public Release: 30-Jul-2015
ZooKeys
I think I found a new species, now how do I illustrate it?
No matter if you are a specialist or not, there is one vital rule in illustrating descriptions of new plant or animal species: you have to do it! A paper published in the open-access journal ZooKeys describes a new fast and free method to make accurate digital line drawings.

Contact: Giuseppe Montesanto
giuseppe.montesanto@unipi.it
Pensoft Publishers

Public Release: 30-Jul-2015
Cell
Take a trip through the brain
A new imaging tool developed by Boston scientists could do for the brain what the telescope did for space exploration. In the first demonstration of how the technology works, published in Cell, the researchers look inside the brain of an adult mouse at a scale previously unachievable, generating images at a nanoscale resolution. The inventors' goal is to make the resource available to the scientific community in the form of a national brain observatory.

Contact: Joseph Caputo
jcaputo@cell.com
617-397-2802
Cell Press

Public Release: 30-Jul-2015
GigaScience
Reproducible research for biofuels and biogas
New research in the open-access journal GigaScience presents a virtual package of data for the production of biogas, which is promising for use in biofuels. Biogas is the production of methane through the anaerobic digestion (fermentation) of organic matter. The work here provides not only an enormous amount of, freely available, data; but is also presented in a reproducible, reusable containerized form, allowing scientists to recreate the experiments at the touch of a button.
Deutsche Forschungsgemeinschaft, OpenAccess Publication Funds of Bielefeld University, Federal Ministry of Food and Agriculture, German Federal Ministry of Education and Research, CLIB Graduate Cluster Industrial Biotechnology

Contact: Scott Edmunds
scott@gigasciencejournal.com
852-361-03531
GigaScience

Public Release: 29-Jul-2015
UT Arlington Interdisciplinary Research Program projects reach across disciplines
Five collaborative research projects involving faculty from seven colleges and schools ranging from innovations in pain management to personal security have won inaugural Interdisciplinary Research Program awards through a University of Texas at Arlington initiative aimed at advancing true interdisciplinary research and enhance the University's competitive position nationally.
University of Texas at Arlington

Contact: Herb Booth
hbooth@uta.edu
817-272-7075
University of Texas at Arlington

Public Release: 29-Jul-2015
Human Molecular Genetics
Long telomere length associated with increased lung cancer risk
A large-scale genetic study of the links between telomere length and risk for five common cancers finds that long telomeres are associated with an increased risk of lung adenocarcinoma. No significant associations between telomere length and other cancer types were observed. The study uses a novel method to measure genetic predisposition for telomere length, rather than physiological measures which are confounded by factors such as age and lifestyle.
NIH/National Cancer Institute, NIH/National Institute on Aging, Cancer Research Foundation, Wellcome Trust, National Health and Medical Research Council

Contact: Kevin Jiang
kevin.jiang@uchospitals.edu
773-795-5227
University of Chicago Medical Center

Public Release: 28-Jul-2015
Journal of American Chemical Society
Understanding the molecular origin of epigenetic markers
The study published in the Journal of the American Chemical Society reveals the effect of lysine acetylation in histone tails.

Contact: Sònia Armengou
armengou@irbbarcelona.org
34-934-037-255
Institute for Research in Biomedicine (IRB Barcelona)

Public Release: 28-Jul-2015
Nature Genetics
Major European mouse study reveals the role of genes in disease
The role of over 300 genes has been revealed by scientists across Europe in a major initiative to understand the part they play in disease and biology. The results have now been published in the journal 'Nature Genetics'.
European Commission, Government of Canada through Genome Canada and Genome Prairie, French state funds through the 'Agence Nationale de la Recherche',

Contact: Martin Hrabe de Angelis
hrabe@helmholtz-muenchen.de
49-893-187-3502
Helmholtz Zentrum München - German Research Center for Environmental Health

Public Release: 27-Jul-2015
Nature Genetics
Yale study identifies 'major player' in skin cancer genes
A multidisciplinary team at Yale, led by Yale Cancer Center members, has defined a subgroup of genetic mutations that are present in a significant number of melanoma skin cancer cases. Their findings shed light on an important mutation in this deadly disease, and may lead to more targeted anti-cancer therapies.
Yale SPORE in Skin Cancer, NIH/National Cancer Institute, US National Institutes of Health, Melanoma Research Alliance, Gilead Sciences, Inc., Howard Hughes Medical Institute

Contact: Ziba Kashef
ziba.kashef@yale.edu
203-436-9317
Yale University

Public Release: 23-Jul-2015
Cell
An innovative algorithm is helping scientists decipher how drugs work inside the body
Researchers have developed a computer algorithm that is helping scientists see how drugs produce pharmacological effects inside the body.
National Institutes of Health

Contact: Lucky Tran
lucky.tran@columbia.edu
212-305-3689
Columbia University Medical Center

Public Release: 23-Jul-2015
AIBS Complex Data Integration Workshop
Biologists identify ways to enhance complex data integration across research domains
The American Institute of Biological Sciences has published a new report that identifies key barriers to complex data integration and offers recommendations for the research community, research funding organizations, and others.
National Science Foundation

Contact: Julie Palakovich Carr
jpalakovichcarr@aibs.org
202-568-8117
American Institute of Biological Sciences

Public Release: 23-Jul-2015
BioTechniques
Faster, better, cheaper: A new method to generate extended data for genome assemblies
Scientists at The Genome Analysis Centre have developed a new library construction method for genome sequencing that can simultaneously construct up to 12 size-selected long mate pair or 'jump' libraries ranging in sizes from 1.7kb to 18kb with reduced DNA input, time and cost.

Contact: Hayley London
hayley.london@tgac.ac.uk
44-160-345-0107
The Genome Analysis Centre

Public Release: 21-Jul-2015
PeerJ
DNA sequencing of noninvasively collected hair expands the field of conservation genetics
Information embedded within DNA has long contributed to biodiversity conservation, helping to reconstruct the past history of species, assess their current status, and guide strategies for their protection. A new study shows that the entire genome of hard to study species may now be available to scientists without the need to handle or even see their study organism, opening up the field of conservation genomics to the use of noninvasive sampling techniques.

Contact: Michael Russello
michael.russello@ubc.ca
250-807-8762
PeerJ

Public Release: 20-Jul-2015
Yale leads NIH-funded autism biomarkers study of pre-school and school-aged children
Yale School of Medicine researchers will lead a national multi-center study of preschool and school-aged children with Autism Spectrum Disorders to identify non-invasive biological markers (biomarkers) that could help physicians diagnose, track, and assess treatments in autism patients.
NIH/National Institutes of Mental Health, Foundation for the National Institutes of Health, Simons Foundation Autism Research Initiative, Yale Clinical and Translational Science Award

Contact: Karen N. Peart
karen.peart@yale.edu
203-432-1326
Yale University

Showing releases 26-50 out of 828.

<< < 1 | 2 | 3 | 4 | 5 | 6 > >>