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Key: Meeting M      Journal J      Funder F

Showing releases 251-275 out of 846.

<< < 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 > >>

Public Release: 9-Apr-2015
Molecular Genetics & Genomic Medicine
TGen finds likely genetic source of muscle weakness in 6 previously undiagnosed children
TGen scientists, using state-of-the-art genetic technology, have discovered the likely cause of a child's rare type of severe muscle weakness. The child was one of six cases in which TGen sequenced -- or decoded -- the genes of patients with Neuromuscular Disease and was then able to identify the genetic source, or likely genetic source, of each child's symptoms, according to a study published April 8 in the journal Molecular Genetics & Genomic Medicine.
Muscular Dystrophy Association, Flinn Foundation, Helios Education Foundation, Freeport-McMoRan Copper & Gold Foundation, and Arizona Biomedical Research Commission

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 9-Apr-2015
NSF brings together UT Dallas computer scientists, industry for new tech hub
UT Dallas computer scientists hope that funding from the National Science Foundation to create an Industry/University Cooperative Research Center will help the Dallas area become a research hub for technology that enhances human abilities.
National Science Foundation

Contact: LaKisha Ladson
University of Texas at Dallas

Public Release: 9-Apr-2015
Nature Communications
Epigenomic changes play an important role during the progression of melanoma
KU Leuven researchers have zeroed in on what makes cancer cells in melanoma so aggressive. They also succeeded in taming the effect in cell cultures. Melanoma, a type of skin cancer, is notoriously quick to metastasize and responds poorly to existing cancer treatments. In their study, published in Nature Communications, the researchers report a significant step forward in the characterization and potential treatment of melanoma.

Contact: Katrien Bollen
KU Leuven

Public Release: 8-Apr-2015
Improved understanding of protein complex offers insight into DNA replication initiation mechanism basics
A clearer understanding of the origin recognition complex -- a protein complex that directs DNA replication -- through its crystal structure offers new insight into fundamental mechanisms of DNA replication initiation. This will also provide insight into how ORC may be compromised in a subset of patients with Meier-Gorlin syndrome, a form of dwarfism in humans.
National Institutes of Health, US Department of Energy

Contact: Tona Kunz
DOE/Argonne National Laboratory

Public Release: 8-Apr-2015
Hidden burden: Most people carry recessive disease mutations
Humans carry an average of one to two mutations per person that can cause severe genetic disorders or prenatal death when two copies of the same mutation are inherited, according to estimates published today in the journal Genetics. The new numbers were made possible by a long-term collaboration between medical researchers and a unique community that has maintained detailed family histories for many generations.

Contact: Cristy Gelling
Genetics Society of America

Public Release: 8-Apr-2015
Journal of the National Cancer Institute
Genetic screening could improve breast cancer prevention
A test for a wide range of genetic risk factors could improve doctors' ability to work out which women are at increased risk of developing breast cancer, a major study of more than 65,000 women has shown. Improving the accuracy of risk analysis using genetic screening could guide breast cancer prevention in several ways -- for instance by offering high-risk women increased monitoring, personalized advice and preventative therapies.
Cancer Research UK, European Union, Breakthrough Breast Cancer, National Institutes of Health

Contact: Henry French
Institute of Cancer Research

Public Release: 7-Apr-2015
Human Genome Variation
A better biomarker to predict cetuximab response in CRC patients
Scientists at Insilico Medicine Inc. and Champions Oncology Inc. have successfully demonstrated a method to predict response to cetuximab in patients with colorectal cancer using OncoFinder pathway activation strength. The study identified a novel prognostic marker in colorectal cancer treated with cetuximab.

Contact: Qingsong Zhu
InSilico Medicine, Inc.

Public Release: 7-Apr-2015
Seena Magowitz Foundation funds TGen's zebrafish studies of pancreatic cancer
Today, scientists at the Translational Genomics Research Institute (TGen) are using zebrafish to accelerate investigations of pancreatic cancer, the nation's fourth-leading cause of cancer-related death. The studies are funded by the Scottsdale, Arizona-based Seena Magowitz Foundation. The amount of the funding was not disclosed.
Seena Magowitz Foundation

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 6-Apr-2015
ROIS collaboration on Data Centric Science
ROIS based in Tokyo signed MoUs on Data Centric Science research collaboration with European organizations, CSC -- IT Center for Science, Finland, DSI and EUDAT. The MoUs were signed on Feb. 25-26 in Tokyo, and are expected to form the basis of further collaboration between the parties.
Research Organization of Information and Systems

Contact: Ms. Rue Ikeya
Research Organization of Information and Systems

Public Release: 6-Apr-2015
Cancer Biotherapy and Radiopharmaceuticals
Can cancer vaccines prolong survival?
Therapeutic anti-cancer vaccines developed to treat metastatic disease such as advanced prostate cancer or melanoma rarely have a noticeable effect on the tumor but have been associated with a statistically significant increase in patient survival. Robert O. Dillman, M.D., NeoStem Inc., asserts that 'overall survival' rather than 'progression-free survival' should be the gold standard for evaluating the efficacy of cancer vaccines in clinical trials, in a provocative new article published in Cancer Biotherapy and Radiopharmaceuticals.

Contact: Kathryn Ryan
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 2-Apr-2015
Journal of Applied Ecology
Bridging the gap between biodiversity data and policy reporting needs
Reporting under policy instruments to inform on the trends in biodiversity requires information from a range of different elements of biodiversity, from genetically viable populations to the structure of ecosystems. A new research funded by the EU FP7 project EU BON looks into the Essential Biodiversity Variables as an analytic framework to identify ways in which gaps between biodiversity data and policy reporting needs could be bridged.

Contact: Dr. Ilse Geijzendorffer
Pensoft Publishers

Public Release: 1-Apr-2015
Genome Research
Longer DNA fragments reveal rare species diversity
A challenge in metagenomics is that the more commonly used sequencing machines generate data in short lengths, while short-read assemblers may not be able to distinguish among multiple occurrences of the same or similar sequences, making it difficult to identify all the members in a microbial community. In the April 2015 issue of Genome Research, a team including DOE JGI researchers compared two ways of using next generation Illumina sequencing machines to help with this.
DOE/Office of Science

Contact: David Gilbert
DOE/Joint Genome Institute

Public Release: 1-Apr-2015
Scientists drill down to genetic root of prostate tumor development
Scientists have revealed the root of prostate cancers in individual men, discovering that despite huge genetic variety between tumors they also share common gene faults -- insight that could offer new treatment hopes.

Contact: Emily Head
Cancer Research UK

Public Release: 31-Mar-2015
Applications in Plant Sciences
Simplifying SNP discovery in the cotton genome
Researchers have developed a strategy that simplifies the discovery of useful single-nucleotide polymorphisms within the complex cotton genome. This method, recently published in Applications in Plant Sciences, will be useful for marker-assisted selection, linkage and QTL mapping, and genetic diversity studies. It has the added benefit of being applicable to other economically important allotetraploid species, including the brassicas, and can be extended to species that do not currently have a reference genome.
Cotton Incorporated Fellowship

Contact: Beth Parada
Botanical Society of America

Public Release: 31-Mar-2015
Four centers in Spain join forces to bridge the gap between research and clinical practice
Today, four centers in Barcelona jointly launch a program that seeks to offer advanced research training for physicians and to strengthen the collaboration between basic research centers and hospitals.

Contact: Laia Cendrós
Center for Genomic Regulation

Public Release: 30-Mar-2015
Scientists honored in Biochemical Society awards
Eleven distinguished scientists and exceptional early career researchers have been honored in the Biochemical Society's annual awards.

Contact: Alastair Stewart
Biochemical Society

Public Release: 30-Mar-2015
Journal of Clinical Investigation
DNA alterations may predict treatment response in chronic myelomonocytic leukemia patients
A new study in the Journal of Clinical Investigation identifies a molecular signature that is predictive of chronic myelomonocytic leukemia patient response to the DNA methyltransferase inhibitor decitabine.
Leukemia and Lymphoma Society, Sass Foundation, National Institutes of Health, US Department of Defense, Josie Robertson Investigator Program, Damon Runyon Clinical Investigator Award, Evans Foundation, French National Cancer Institute

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 26-Mar-2015
Sea slug provides new way of analyzing brain data
Scientists say our brains may not be as complicated as we once thought -- and they're using sea slugs to prove it.
Medical Research Council, Agence Nationale de la Recherche

Contact: Morwenna Grills
University of Manchester

Public Release: 25-Mar-2015
Mobile DNA sequencer shows potential for disease surveillance
A pocket-sized device that can rapidly determine the sequence of an organism's DNA has shown its potential in disease detection, according to a study published in the open access, open data journal GigaScience.

Contact: Joel Winston
BioMed Central

Public Release: 23-Mar-2015
Journal of Clinical Microbiology
Unraveling cystic fibrosis puzzle, taking it personally matters
A comprehensive bioinformatics analysis of human lung bacteria from a uniquely detailed, long-term data set has discovered a previously unknown relationship between population changes in a single bacterial species and subsequent flare-ups of disease in cystic fibrosis. The study was made possible by the unusual cooperation of a single cystic fibrosis patient -- the lead author in the study.
National Institutes of Health, Cystic Fibrosis Foundation

Contact: James Hathaway
University of North Carolina at Charlotte

Public Release: 23-Mar-2015
Cell Reports
Cytomegalovirus hijacks human enzyme for replication
Researchers at Princeton have discovered that cytomegalovirus manipulates a process called fatty acid elongation, which makes the very-long-chain fatty acids necessary for virus replication. Published in the journal Cell Reports on March 3, the research team identified a specific human enzyme -- elongase enzyme 7 -- that the virus induces to turn on fatty acid elongation.
National Institutes of Health, American Heart Association

Contact: Tien Nguyen
Princeton University

Public Release: 20-Mar-2015
Journal of Antimicrobial Chemotherapy
Scientists must reduce antibiotic use in experiments
Scientists should reduce antibiotic use in lab experiments -- according to a researcher at the University of East Anglia. Microbiology, molecular biology and genetic research such as the Human Genome Project use antibiotics in experiments. But it all adds to the global problem of antibiotic resistance according to Dr. Laura Bowater, from UEA's Norwich Medical School.

Contact: Lisa Horton
University of East Anglia

Public Release: 19-Mar-2015
Advances in Genome Biology & Technology (AGBT) 2015
TGAC's take on the first portable DNA sequencing 'laboratory'
The Genome Analysis Centre (TGAC) take part in ground breaking portable DNA sequencing trial, the MinION Access Programme. The first remote laboratory will allow TGAC's researchers to carry out live experiments for immediate analysis out in the field.
Oxford Nanopore Technologies

Contact: Hayley London
The Genome Analysis Centre

Public Release: 18-Mar-2015
Nucleic Acids Research
Los Alamos creates bioinformatics tool for metagenome analysis
Scientists at Los Alamos National Laboratory have developed a new method for DNA analysis of microbial communities such as those found in the ocean, the soil, and our own guts.
Defense Threat Reduction Agency/Chemical and Biological Technologies-Joint Science and Technology Office

Contact: Nancy Ambrosiano
DOE/Los Alamos National Laboratory

Public Release: 17-Mar-2015
New metabolic mechanisms discovered that regulate the macrophage's role in immune response
A group of researchers from Washington University in St. Louis, Agios Pharmaceuticals and ITMO University has discovered new metabolic mechanisms that regulate macrophage polarization - the unique ability of these immune cells to change their specialization depending on the required task. The research opens new possibilities for the development of a new class of drugs based on controlling the metabolism of immune cells. The results were published today in the Immunity journal.

Contact: Dmitry Malkov
ITMO University

Showing releases 251-275 out of 846.

<< < 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 > >>