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Key: Meeting M      Journal J      Funder F

Showing releases 351-375 out of 707.

<< < 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 > >>

Public Release: 19-Nov-2013
Study to identify functions of hypothetical genes in 2 infectious disease pathogens
The National Institute of Allergy and Infectious Diseases has awarded the University of Chicago $4.4 million over five years to study genes of unknown function in bacteria that cause plague and brucellosis.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Kevin Jiang
kevin.jiang@uchospitals.edu
773-795-5227
University of Chicago Medical Center

Public Release: 17-Nov-2013
Nature Methods
Protein coding 'junk genes' may be linked to cancer
By using a new analysis method, researchers at Karolinska Institutet and Science for Life Laboratory in Sweden have found close to one hundred novel human gene regions that code for proteins. A number of these regions are so-called pseudogenes, which may be linked to cancer.
Swedish Research Council, Swedish Cancer Society, EU FP7 project GlycoHit, and others

Contact: The Press Office
pressinfo@ki.se
46-852-486-077
Karolinska Institutet

Public Release: 14-Nov-2013
Journal of Experimental Medicine
A*STAR scientists bring to light mechanism of drug for infections
Scientists at A*STAR's Singapore Immunology Network have discovered the exact mode of action by plerixafor, a drug commonly prescribed to stimulate immune responses in patients suffering from neutropenia, which causes them to become prone to oral, skin, genital infections and in worst cases, a fatal whole-body infection . A better understanding of the drug's mechanism can improve its usage to more effectively reduce risk of infections in these patients.

Contact: Tan Yun Yun
tan_yun_yun@a-star.edu.sg
65-682-66273
Agency for Science, Technology and Research (A*STAR), Singapore

Public Release: 13-Nov-2013
Molecular Cell
Deletion of any single gene provokes mutations elsewhere in the genome
Johns Hopkins researchers report that the deletion of any single gene in yeast cells puts pressure on the organism's genome to compensate, leading to a mutation in another gene. Their discovery, which is likely applicable to human genetics because of the way DNA is conserved across species, could have significant consequences for the way genetic analysis is done in cancer and other areas of research, they say.
NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute of General Medical Sciences

Contact: Catherine Kolf
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine

Public Release: 13-Nov-2013
PLOS ONE
Gut microbes in healthy kids carry antibiotic resistance genes
Friendly microbes in the intestinal tracts of healthy American children have numerous antibiotic resistance genes, according to results of a pilot study by scientists at Washington University School of Medicine in St. Louis. The genes are cause for concern because they can be shared with harmful microbes, interfering with the effectiveness of antibiotics in ways that can contribute to serious illness and, in some cases, death.

Contact: Michael C. Purdy
purdym@wustl.edu
314-286-0122
Washington University School of Medicine

Public Release: 13-Nov-2013
Wireless sensors used to study meditation's effect on heart health
Demystifying meditation with science, researchers at the Scripps Translational Science Institute have teamed with The Chopra Foundation and The Chopra Center for Wellbeing in a novel study of the ancient practice that uses wireless health sensors to collect physiological data from meditators. The research might for the first time demonstrate the immediate influence of meditation on blood pressure and markers of stress, and eventually guide better and more individualized treatments.
Chopra Foundation

Contact: Keith Darce
darce.keith@scrippshealth.org
858-678-7121
Scripps Health

Public Release: 10-Nov-2013
Philosophical Transactions of the Royal Society B
Fast-mutating DNA sequences shape early development; guided evolution of uniquely human traits
What does it mean to be human? According to scientists the key lies, ultimately, in the billions of lines of genetic code that comprise the human genome. The problem, however, has been deciphering that code. But now, researchers at the Gladstone Institutes have discovered how the activation of specific stretches of DNA control the development of uniquely human characteristics -- and tell an intriguing story about the evolution of our species.
NIH/National Institute of General Medical Sciences, NIH/National Heart, Lung and Blood Institute

Contact: Anne Holden
anne.holden@gladstone.ucsf.edu
415-734-2534
Gladstone Institutes

Public Release: 10-Nov-2013
Nature Biotechnology
Single-cell genome sequencing gets better
Researchers led by bioengineers at the University of California, San Diego have generated the most complete genome sequences from single E. coli cells and individual neurons from the human brain. Preliminary data suggest that individual neurons from the same brain have different genetic compositions. The breakthrough, published in Nature Biotechnology, comes from a new single-cell genome sequencing technique that confines genome amplification to fluid-filled wells with a volume of just 12 nanoliters.
National Institutes of Health, US National Science Foundation

Contact: Daniel Kane
dbkane@ucsd.edu
858-534-3262
University of California - San Diego

Public Release: 8-Nov-2013
Journal of Biological Chemistry
TGen-led study reveals TWEAK-Fn14 as key drug target
A cellular pathway interaction known as TWEAK-Fn14, often associated with repair of acute injuries, also is a viable target for drug therapy that could prevent the spread of cancer, especially brain cancer, according to a study led by the Translational Genomics Research Institute.
Ben and Catherine Ivy Foundation, NIH/National Cancer Institute

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute

Public Release: 7-Nov-2013
PLOS Genetics
Dartmouth researcher finds novel genetic patterns that make us rethink biology and individuality
Scott Williams, Ph.D., of the iQBS at Dartmouth, has made two novel discoveries: 1) a person can have several DNA mutations in parts of their body, with their original DNA in the rest -- resulting in several different genotypes in one individual -- and 2) some of the same genetic mutations occur in unrelated people. We think of each person's DNA as unique, but if a person can have more than one genotype, this may have broad implications.
National Institutes of Health

Contact: Derik Hertel
derik.hertel@dartmouth.edu
603-650-1203
The Geisel School of Medicine at Dartmouth

Public Release: 7-Nov-2013
Nature Biotechnology
Cost-effective method accurately orders DNA sequencing along entire chromosomes
A new computational method has been shown to quickly assign, order and orient DNA sequencing information along entire chromosomes. The method may help overcome a major obstacle that has delayed progress in designing rapid, low-cost -- but still accurate -- ways to assemble genomes from scratch. Data gleaned through this new method can also validate certain types of chromosomal abnormalities in cancer.
National Institutes of Health, NIH/National Human Genome Research Institute, National Science Foundation

Contact: Leila Gray
leilag@uw.edu
206-685-0381
University of Washington

Public Release: 7-Nov-2013
UNH, UC Davis launch network to study environmental microbes
A grant to the University of New Hampshire and the University of California, Davis, will help biologists identify an abundant yet largely unknown category of organisms, leading to better understanding of the vital environmental functions they play. The National Science Foundation awarded the universities $500,000 to develop a Research Coordination Network on eukaryotic biodiversity. The work will apply new genome sequencing technology to study and classify microscopic eukaryote species like nematodes, fungi, and single-celled animals.
National Science Foundation

Contact: Beth Potier
beth.potier@unh.edu
603-862-1566
University of New Hampshire

Public Release: 7-Nov-2013
Allen Institute for Brain Science partners with imec for development of next-generation tools
The Allen Institute in partnership with imec, the Howard Hughes Medical Institute, the Gatsby Charitable Foundation, the Wellcome Trust and University College London, have committed $5.5 million in R&D for the revolutionary neuroscience research tools including the proposed sensor array.

Contact: Steven Cooper
press@alleninstitute.org
646-358-2765
Edelman Public Relations

Public Release: 6-Nov-2013
ZooKeys
Nature's great diversity: Remarkable 277 new wasp species from Costa Rica
Costa Rica reveals astonishing biodiversity of braconid wasps, with 277 new species of the tribe Heterospilini described, from a total of 286 attributed to the group. The study published in the open access journal ZooKeys is the second part of an extensive two-part study of the braconid subfamily Doryctinae from Costa Rica, to reveal the great species diversity within such a small territory.

Contact: Paul M. Marsh
swampy@wildblue.net
Pensoft Publishers

Public Release: 4-Nov-2013
Strata + Hadoop World 2013
New computing model could lead to quicker advancements in medical research, according to Virginia Tech
For the past two years, Wu Feng has led a research team that has now created a new generation of efficient data management and analysis software for large-scale, data-intensive scientific applications in the cloud. "Our goal was to keep up with the data deluge in the DNA sequencing space. Our result is that we are now analyzing data faster, and we are also analyzing it more intelligently," Feng said.
National Science Foundation and Microsoft

Contact: Lynn Nystrom
tansy@vt.edu
540-231-4371
Virginia Tech

Public Release: 4-Nov-2013
Nature Genetics
Mutations linked to breast cancer treatment resistance
Researchers at the University of Michigan Comprehensive Cancer Center have identified a type of mutation that develops after breast cancer patients take anti-estrogen therapies. The mutations explain one reason why patients often become resistant to this therapy.
NIH/Clinical Sequencing Exploratory Research Consortium

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 4-Nov-2013
ZooKeys
Next-generation global e-infrastructure for taxon names registry
Issue no. 346 of ZooKeys has been automatically registered in ZooBank on its day of publication last Friday. This marks the successful deployment of an automated registration-to-publication pipeline for taxonomic names for animals. The innovative workflow sets directions towards building a next-generation e-infrastructure for a common global taxon names registry.

Contact: Dr. Richard Pyle
deepreef@bishopmuseum.org
Pensoft Publishers

Public Release: 1-Nov-2013
ZooKeys
GenSeq: Updated nomenclature for genetic sequences to solve taxonomic determination issues
An improved and expanded nomenclature for genetic sequences is introduced that corresponds with a ranking of the reliability of the taxonomic identification of the source specimens. Verifying the taxonomic identity of the voucher specimens that are the source of genetic materials has become increasingly difficult but remains vitally important; this new nomenclatural system for DNA sequences helps remedy this issue. The study was published in the open access journal Zookeys.

Contact: Prosanta Chakrabarty
prosanta@lsu.edu
Pensoft Publishers

Public Release: 31-Oct-2013
PLOS Computational Biology
Automated system promises precise control of medically induced coma
Putting patients with severe head injuries or persistent seizures into a medically induced coma currently requires that a nurse or other health professional constantly monitor the patient's brain activity and manually adjust drug infusion to maintain a deep state of anesthesia. Now a computer-controlled system developed by Massachusetts General Hospital investigators promises to automate the process, making it more precise and efficient and opening the door to more advanced control of anesthesia.
National Institutes of Health

Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital

Public Release: 31-Oct-2013
Journal of Clinical Investigation
Newly identified proteins make promising targets for blocking graft-vs.-host disease
Researchers from the University of Michigan Comprehensive Cancer Center have identified new proteins that control the function of critical immune cell subsets called T-cells, which are responsible for a serious and often deadly side effect of lifesaving bone marrow transplants.
National Institutes of Health, Leukemia Lymphoma Society, American Society of Transplantation

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 31-Oct-2013
Cell Reports
Researchers discover how retinal neurons claim the best brain connections
Virginia Tech Carilion Research Institute scientists have discovered how retinal neurons claim prime real estate in the brain by controlling the abundance of a protein called aggrecan. The discovery could shed light on how to repair the injured brain.

Contact: Paula Byron
pbyron@vt.edu
540-526-2027
Virginia Tech

Public Release: 31-Oct-2013
Current Biology
Cellular tail length tells disease tale
Simon Fraser University molecular biologist Lynne Quarmby's adventures in pond scum have led her and four student researchers to discover a mutation that can make cilia, the microscopic antennae on our cells, grow too long. When the antennae aren't the right size, the signals captured by them get misinterpreted. The result can be fatal. They have discovered that the regulatory gene CNK2 is present in cilia and controls the length of these hair-like projections.

Contact: Carol Thorbes
cthorbes@sfu.ca
778-782-3035
Simon Fraser University

Public Release: 31-Oct-2013
Cell Reports
Evolution of new species requires few genetic changes
Only a few genetic changes are needed to spur the evolution of new species -- even if the original populations are still in contact and exchanging genes. Once started, however, evolutionary divergence evolves rapidly, ultimately leading to fully genetically isolated species, report scientists from the University of Chicago in the Oct. 31 Cell Reports.
National Science Foundation

Contact: Kevin Jiang
kevin.jiang@uchospitals.edu
773-795-5227
University of Chicago Medical Center

Public Release: 30-Oct-2013
Switzerland signs the ELIXIR consortium agreement and contributes €35 million
Switzerland's State Secretary for Education, Research and Innovation, Dr. Mauro Dell'Ambrogio, has signed the ELIXIR consortium agreement for the establishment of ELIXIR, the European Life Science Infrastructure for Biological Information.

Contact: Irene Perovsek
irene.perovsek@isb-sib.ch
41-216-924-054
Swiss Institute of Bioinformatics

Public Release: 30-Oct-2013
PLOS ONE
Absence of the SMG1 protein could contribute to Parkinson's and other neurological disorders
The absence of a protein called SMG1 could be a contributing factor in the development of Parkinson's disease and other related neurological disorders, according to a study led by the Translational Genomics Research Institute.
Arizona Parkinson's Disease Consortium

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute

Showing releases 351-375 out of 707.

<< < 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 > >>