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Key: Meeting M      Journal J      Funder F

Showing releases 351-375 out of 747.

<< < 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 > >>

Public Release: 21-Mar-2014
With a few finger taps, draw genetic pedigrees at point of care with new app
Long used in genetic medicine, pedigrees are diagrams that show how inherited diseases may recur in a particular family. A new app adds a digital spin, letting clinicians create pedigrees with a few finger taps during a patient encounter.
NIH/National Human Genome Research Institute

Contact: John Ascenzi
Children's Hospital of Philadelphia

Public Release: 20-Mar-2014
Cancer Cell
Study reveals a major mechanism driving kidney cancer progression
The shortage of oxygen, or hypoxia, created when rapidly multiplying kidney cancer cells outgrow their local blood supply can accelerate tumor growth by causing a nuclear protein called SPOP -- which normally suppresses tumor growth -- to move out of the nucleus to the cytoplasm, where it has the opposite effect, promoting rapid proliferation. This cytoplasmic accumulation of SPOP is sufficient to convey tumorigenic properties onto otherwise non-tumorigenic cells.
National Institutes of Health, Beijing Science Foundation, Keck Foundation, Chicago Community Trust, Chicago Biomedical Consortium

Contact: John Easton
University of Chicago Medical Center

Public Release: 19-Mar-2014
World Journal of Surgery
TGen study identifies gene fusion as likely cause of rare type of thyroid cancer
In a scientific first, the fusion of two genes, ALK and EML4, has been identified as the genetic driver in an aggressive type of thyroid cancer, according to a study by the Translational Genomics Research Institute. These groundbreaking findings are based on genetic sequencing of tumor cells from a 62-year-old patient with an aggressive tall cell variant of papillary thyroid cancer, according to the study published Tuesday, March 18, in the World Journal of Surgery.

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 19-Mar-2014
Molecular Systems Biology
101 liver cancer drug candidates pave the way to personalized medicine
The heart disease drug perhexiline is one of 101 compounds predicted to prevent cancer growth in most patients suffering from our most common liver cancer, HCC. This is an outcome from a novel simulation-based approach using personal sets of proteins of six HCC patients. 'This is the first time personalized models have been used to find and evaluate new potential drugs,' says professor Jens Nielsen at Chalmers University of Technology.
Knut and Alice Wallenberg Foundation

Contact: Christian Borg
Chalmers University of Technology

Public Release: 18-Mar-2014
Journal of Economic Entomology
Planting cotton early may mean less stink bug damage
New research published in the Journal of Economic Entomology shows that planting cotton early in the planting window will allow growers to escape peak stink bug pressure and thereby possibly eliminate or minimally reduce the number of sprays required to manage them.

Contact: Richard Levine
Entomological Society of America

Public Release: 18-Mar-2014
From DNA to diagnosis
Compared to 10 years ago, sequencing the human genome has plummeted in cost by one-million-fold and can be completed in a fraction of the time. Yet there are still barriers preventing DNA sequence information from routinely being incorporated into patient care. The USTAR Center for Genetic Discovery is partnering with California-based Omicia Inc. to make patient genome analysis as routine as a blood test.

Contact: Julie Kiefer
University of Utah Health Sciences

Public Release: 18-Mar-2014
TGen-led study spotlights dog DNA role in developing new therapies for human cancers
Using genomic analysis to study cancer in dogs can help develop new therapies for humans with cancer, according to a proof-of-concept study led by the National Cancer Institute and the Translational Genomics Research Institute.
National Institutes of Health

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 17-Mar-2014
Nature Methods
Immunologists present improved mass spectrometric method for proteomic analyses
Mass spectrometry is a highly sensitive method of measurement that has been used for many years for the analysis of chemical and biological materials. Scientists at the Institute of Immunology of the University Medical Center of Johannes Gutenberg University Mainz have now significantly improved this analytical method that is widely employed within their field.

Contact: Dr. Stefan Tenzer
Johannes Gutenberg Universitaet Mainz

Public Release: 17-Mar-2014
Closer to detecting preeclampsia
Researchers have found a set of biomarkers in urine and serum samples that were different between women with preeclampsia, women with normal pregnancies and women who were not pregnant. These biomarkers tell the story of what is happening to the metabolism of women who have developed preeclampsia.

Contact: Marie Austdal
Norwegian University of Science and Technology

Public Release: 16-Mar-2014
Nature Genetics
Novel gene-finding approach yields a new gene linked to key heart attack risk factor
Scientists have discovered a previously unrecognized gene variation that makes humans have healthier blood lipid levels and reduced risk of heart attacks -- a finding that opens the door to using this knowledge in testing or treatment of high cholesterol and other lipid disorders. But even more significant is how they found the gene, which had been hiding in plain sight in previous hunts for genes that influence cardiovascular risk.
National Institutes of Health, Norwegian HUNT

Contact: Kara Gavin
University of Michigan Health System

Public Release: 16-Mar-2014
Newly identified small-RNA pathway defends genome against the enemy within
For a plant to create reproductive cells, it must first erase a series of tags attached to DNA across the genome that distinguish active and inactive genes. But the marks also keep a host of damaging 'jumping genes' inactive. As the cell wipes away the marks, it activates transposons, which can cause genetic damage. Researchers at CSHL have discovered a fail-safe mechanism that helps to keep transposons inactive even when these marks are erased.
DuPont Pioneer, National Institutes of Health, Howard Hughes Medical Institute

Contact: Jaclyn Jansen
Cold Spring Harbor Laboratory

Public Release: 16-Mar-2014
Nature Genetics
Cancer therapy may be too targeted
Targeted therapies seem to be the future of cancer treatment, but can they be too narrowly focused? In a study published in Nature Genetics, scientists have found that for a rare cancer of the blood vessel where several mutations can underlie the disease, many different parts of the pathway can be disrupted. For patients with multiple underlying mutations, previously developed therapies that focus on targeting a single component in the pathway will be ineffective.
Wellcome Trust

Contact: Mary Clarke
Wellcome Trust Sanger Institute

Public Release: 13-Mar-2014
Bioscientists develop 'grammar' to design useful synthetic living systems
Researchers at the Massachusetts Institute of Technology and Virginia Tech have used a computer-aided design tool to create genetic languages to guide the design of biological systems.
Defense Advanced Research Projects Agency, National Institutes of Health, National Science Foundation, Office of Naval Research

Contact: Tiffany Trent
Virginia Tech

Public Release: 13-Mar-2014
67th SSO Annual Cancer Symposium
Pancreatic cancer surgery findings presented at SSO
Despite the benefits of surgery for early stage pancreatic cancer, it remains under-utilized for patients with this deadly disease, according to a new national analysis of trends and outcomes. Physician-scientists at University Hospitals Case Medical Center and Case Western Reserve University School of Medicine presented their findings and strategies to increase rates at the Society of Surgical Oncology Cancer Symposium in Phoenix.

Contact: Alicia Reale
University Hospitals Case Medical Center

Public Release: 13-Mar-2014
Unraveling a mystery in the 'histone code' shows how gene activity is inherited
Every cell in our body has exactly the same DNA, yet every cell is different. The genetic code carried in our DNA provides instructions for cells to manufacture specific proteins. A second code, carried by histone proteins bound to DNA, determines which genes are activated in particular cells. Researchers at CSHL have found that the slightest variation in a histone protein can have dramatic effects on how the genes encoded in our DNA are used.
Howard Hughes Medical Institute, National Science Foundation, National Institutes of Health

Contact: Jaclyn Jansen
Cold Spring Harbor Laboratory

Public Release: 13-Mar-2014
PLOS Computational Biology
Autism and intellectual disability incidence linked with environmental factors
An analysis of 100 million US medical records reveals that autism and intellectual disability rates correlate with genital malformation incidence in newborn males, an indicator of congenital exposure to harmful environmental factors such as pesticides. Autism rates jump by 283 percent for every one percent increase in frequency of malformations in a county. In addition, the study finds that Autism and ID incidence decrease by roughly 99 percent in states with stronger regulations on diagnosis.
NIH/National Institute for Mental Health

Contact: Kevin Jiang
University of Chicago Medical Center

Public Release: 12-Mar-2014
UT Arlington research says treadmill workstation benefits employees, employers
Employees who use treadmill workstations not only receive physical benefits but also are more productive at work, according to a recently published study by researchers from the University of Texas at Arlington, the Mayo Clinic and the University of Minnesota.

Contact: Herb Booth
University of Texas at Arlington

Public Release: 10-Mar-2014
Proceedings of the National Academy of Sciences
A tale of 2 data sets: New DNA analysis strategy helps researchers cut through the dirt
Researchers from Michigan State University, the US Department of Energy Joint Genome Institute and Lawrence Berkeley National Laboratory, have published the largest soil DNA sequencing effort to date in PNAS. What has emerged in this first of the studies to come from this project is a simple, elegant solution to sifting through the deluge of information gleaned, as well as a sobering reality check on just how hard a challenge these environments will be.
Department of Energy Office of Science, US Department of Agriculture, National Science Foundation, Great Lakes Bioenergy Research Center

Contact: David Gilbert
DOE/Joint Genome Institute

Public Release: 9-Mar-2014
Nature Biotechnology
New bioinformatics tool to visualize transcriptomes
ZENBU, a new, freely available bioinformatics tool developed at the RIKEN Center for Life Science Technology in Japan, enables researchers to quickly and easily integrate, visualize and compare large amounts of genomic information resulting from large-scale, next-generation sequencing experiments.

Contact: Juliette Savin

Public Release: 7-Mar-2014
ASCO 50th Annual Meeting
TGen and Scottsdale Healthcare cancer expert Dr. Daniel D. Von Hoff is honored by ASCO
In association with its 50th anniversary, the American Society of Clinical Oncology (ASCO) has named Dr. Daniel D. Von Hoff one of ASCO's 50 Oncology Luminaries, celebrating 50 doctors who over the past half-century have significantly advanced cancer care.

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 7-Mar-2014
Slovak Republic becomes EMBL Prospect Member State
The European Molecular Biology Laboratory (EMBL) welcomes the Slovak Republic as the first country to join its new Prospect Member scheme. In a Statement of Intent signed last month, the Slovak Republic and EMBL agree to explore the possibilities for long-term cooperation, with a view to the country becoming a full Member State within three years.

Contact: Sonia Furtado Neves
European Molecular Biology Laboratory

Public Release: 6-Mar-2014
The genome of sesame sheds new lights on oil biosynthesis
Researchers from Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, BGI, University of Copenhagen and other institutes have successfully cracked the genome of high oil content crop sesame, providing new lights on the important stages of seed development and oil accumulation, and potential key genes for sesamin production.

Contact: Jia Liu
BGI Shenzhen

Public Release: 4-Mar-2014
American Naturalist
Are plants more intelligent than we assumed?
Plants are also able to make complex decisions. At least this is what scientists from the Helmholtz Center for Environmental Research and the University of Goettingen have concluded from their investigations on barberry, which is able to abort its own seeds to prevent parasite infestation. The results are the first ecological evidence of complex behavior in plants.

Contact: Tilo Arnhold
Helmholtz Centre for Environmental Research - UFZ

Public Release: 27-Feb-2014
System-wide analyses have underestimated the importance of transcription in animals
Over the last decade, a number of studies have suggested that, in animal cells, translation and protein turnover play a larger role in determining the different levels at which proteins are expressed than transcription. This new study suggests that the major reason why protein and mRNA abundance measurements are poorly correlated is because of various types of measurement error in the protein and mRNA abundance, rather than transcription having minimal impact on protein expression levels.

Contact: Mark Biggin

Public Release: 27-Feb-2014
A bird's eye view of cellular RNAs
A team at the Wyss Institute of Biologically Inspired Engineering at Harvard University and Harvard Medical School, in collaboration with the Allen Institute for Brain Science, has developed a new method that allows scientists to pinpoint the location of thousands of working copies of genes called mRNAs at once in intact cells -- while simultaneously determining the sequence of letters, or bases, that identify them and reveal their cellular function.

Contact: Dan Ferber
Wyss Institute for Biologically Inspired Engineering at Harvard

Showing releases 351-375 out of 747.

<< < 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 > >>