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Key: Meeting M      Journal J      Funder F

Showing releases 376-400 out of 712.

<< < 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 > >>

Public Release: 2-Aug-2013
Cell
Wired for change
A study of gene expression led by scientists at the EMBL-European Bioinformatics Institute and the University of Cambridge has revealed the first steps of evolution in gene regulation in mice. Published in the journal Cell, the research has implications for the study of differences in gene regulation between people.
European Research Council, Marie Curie Re-Integration Award, EMBO Young Investigator Programme

Contact: Sonia Furtado Neves
sonia.furtado@embl.de
European Molecular Biology Laboratory

Public Release: 1-Aug-2013
Cell
How 'junk DNA' can control cell development
Researchers from the Gene and Stem Cell Therapy Program at Sydney's Centenary Institute have confirmed that, far from being "junk," the 97 percent of human DNA that does not encode instructions for making proteins can play a significant role in controlling cell development. And in doing so, the researchers have unravelled a previously unknown mechanism for regulating the activity of genes, increasing our understanding of the way cells develop and opening the way to new possibilities for therapy.
Centenary Institute

Contact: Tamzin Byrne
tamzin@scienceinpublic.com.au
043-297-4400
Centenary Institute

Public Release: 1-Aug-2013
Cell
Targeted therapy identified for protein that protects and nourishes cancer
UT MD Anderson scientists identify the first targeted therapy to block Skp2, which suppresses a cellular defense against cancer and activates glycolysis to feed tumors. The drug restores the senescence program and stifles glycolysis to thwart tumor progression.
NIH/National Cancer Institute, American Cancer Society, Susan G. Komen for the Cure

Contact: Scott Merville
smerville@mdanderson.org
713-792-0661
University of Texas M. D. Anderson Cancer Center

Public Release: 1-Aug-2013
Cell
New designer compound treats heart failure by targeting cell nucleus
Researchers from Case Western Reserve University School of Medicine and the Dana-Farber Cancer Institute have made a fundamental discovery relevant to the understanding and treatment of heart failure -- a leading cause of death worldwide. The team discovered a new molecular pathway responsible for causing heart failure and showed that a first-in-class prototype drug, JQ1, blocks this pathway to protect the heart from damage.
National Institutes of Health

Contact: Jessica Studeny
Jessica.studeny@case.edu
216-368-4692
Case Western Reserve University

Public Release: 31-Jul-2013
Stem Cells
Computational biology: Cells reprogrammed on the computer
Scientists at the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg have developed a model that makes predictions from which differentiated cells -- for instance skin cells -- can be very efficiently changed into completely different cell types -- such as nerve cells, for example. This can be done entirely without stem cells. These computer-based instructions for reprogramming cells are of huge significance for regenerative medicine. The LCSB researchers present their results today in the prestigious scientific journal "Stem Cells".

Contact: Britta Schlüter
britta.schlueter@uni.lu
352-466-644-6563
University of Luxembourg

Public Release: 31-Jul-2013
Wonders of nature inspire exotic man-made materials
In this month's edition of Physics World, a group of physicists describe how unique structures in the natural world are inspiring scientists to develop new types of materials with unprecedented properties.

Contact: Michael Bishop
michael.bishop@iop.org
01-179-301-032
Institute of Physics

Public Release: 31-Jul-2013
Ecological Society of America 2013 Annual Meeting
Entomological Society of America announces 2013 fellows
The Entomological Society of America has elected ten new Fellows of the Society for 2013. The election as a Fellow acknowledges outstanding contributions to entomology in research, teaching, extension, or administration.

Contact: Richard Levine
rlevine@entsoc.org
301-731-4535
Entomological Society of America

Public Release: 31-Jul-2013
New England Journal of Medicine
ITN achieves scientific manuscript first -- provides open, interactive access to clinical trial data
Immune Tolerance Network researchers published data of their "Rituximab for the Treatment of Wegener's Granulomatosis and Microscopic Polyangiitis (RAVE)" clinical trial using ITN TrialShare, a clinical trial data and analysis portal that provides open, unprecedented access to clinical trial data, analyses and specimens.

Contact: Philip Bernstein, Ph.D.
ITNCommunications@immunetolerance.org
240-235-6132
Immune Tolerance Network

Public Release: 29-Jul-2013
Chaos
Unraveling genetic networks
Now a special issue of the journal CHAOS, produced by AIP Publishing, explores new experimental and theoretical techniques for unraveling genetic networks.

Contact: Jason Socrates Bardi
jbardi@aip.org
240-535-4954
American Institute of Physics

Public Release: 26-Jul-2013
PhytoKeys
Database simplifies finding Canadian plant names and distribution
Determining the correct name of plants present in a particular area is often a chore to users of biodiversity information. VASCAN, the Database of Vascular plants of Canada, Saint Pierre and Miquelon, and Greenland, simplifies the task of finding such names, as well as the plant distribution at a regional level for all vascular plants established in the area covered.

Contact: Dr. Luc Brouillet
luc.brouillet@umontreal.ca
514-343-2142
Pensoft Publishers

Public Release: 25-Jul-2013
PLOS ONE
Microbial who-done-it for biofuels
A multi-institutional collaboration led by researchers with the Joint BioEnergy Institute and Joint Genome Institute has developed a promising technique for identifying microbial enzymes that can effectively deconstruct biomass into fuel sugars under refinery processing conditions.
US Department of Energy Office of Science

Contact: Lynn Yarris
lcyarris@lbl.gov
510-486-5375
DOE/Lawrence Berkeley National Laboratory

Public Release: 23-Jul-2013
HudsonAlpha awarded grant to improve diagnoses of childhood genetic disorders
Even in the absence of a ready solution, knowing why a child faces physical, emotional and intellectual challenges is helpful to physicians and families. Researchers at the HudsonAlpha Institute for Biotechnology are using high throughput genomic sequencing to meet major diagnostic needs for childhood genetic disorders through a multi-year grant potentially totaling more than $7.6 million from the National Institutes of Health. The study grant is part of the NIH's Clinical Sequencing Exploratory Research program.
NIH/National Human Genome Research Institute Clinical Sequencing Exploratory Research

Contact: Holly Ralston
hralston@hudsonalpha.org
256-508-8954
HudsonAlpha Institute for Biotechnology

Public Release: 22-Jul-2013
Diabetes
Could turning on a gene prevent diabetes?
The resistance to insulin seen in type 2 diabetics is caused partly by the lack of a protein that has not previously been associated with diabetes.
Association canadienne du diabète, Instituts de recherche en santé du Canada

Contact: William Raillant-Clark
rw.raillantclark@gmail.com
514-343-7593
University of Montreal

Public Release: 22-Jul-2013
Using GitHub as a repository for machine-readable scholarly articles
Pensoft now provides the XML of all articles in ZooKeys, PhytoKeys and MycoKeys in version-controlled repositories on GitHub for all to see, comment, improve and more. GitHub can be described as a social platform used mostly by software developers for coding, discussing, changing, and keeping track of all that. A major benefit of such re-use is that it acts as an additional check for quality.

Contact: Lyubomir Penev
info@pensoft.net
Pensoft Publishers

Public Release: 18-Jul-2013
Dartmouth researchers aim to discover the unknown causes of premature birth
Dartmouth researchers from the Institute for Quantitative Biomedical Sciences, the Center for Integrative Biomedical Sciences, and the Center for Genomic Medicine at the Geisel School of Medicine are studying the unknown causes of premature birth, as part of a $10 million March of Dimes grant. Scott Williams, Jason Moore and Christopher Amos will examine diverse world populations with different levels of premature birth to understand how genetic variation impacts the underlying biology of preterm birth.
March of Dimes

Contact: Derik Hertel
kenneth.d.hertel@dartmouth.edu
603-650-1211
The Geisel School of Medicine at Dartmouth

Public Release: 18-Jul-2013
Genes & Development
Newly found CLAMP protein regulates genes
A newly discovered protein, found in many species, turns out to be the missing link that allows a key regulatory complex to find and operate on the lone X chromosome of male fruit flies, bringing them to parity with females. Called CLAMP, the protein provides a model of how such regulatory protein complexes find their chromosome targets.
National Institutes of Health, National Science Foundation, Pew Biomedical Scholars Program, Rhode Island Foundation

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University

Public Release: 15-Jul-2013
Clinical trials for cancer, 1 patient at a time
New department at Columbia University Medical Center is developing a different approach to cancer clinical trials, in which therapies are designed and tested one patient at a time. The patient's tumor is "reverse engineered" to determine its unique genetic characteristics and to identify existing US Food and Drug Administration-approved drugs that may target them.

Contact: Karin Eskenazi
ket2116@columbia.edu
212-305-3900
Columbia University Medical Center

Public Release: 11-Jul-2013
AMP concerned about the structure and application of gap fill payment amounts
The Association for Molecular Pathology submitted comments to the Centers for Medicare and Medicaid Services expressing serious concerns about the gap fill process.

Contact: Catherine Davidge
cdavidge@amp.org
301-634-7400
Association for Molecular Pathology

Public Release: 10-Jul-2013
Molecular Biology and Evolution
Malaria in the Americas presents a complex picture
In a new study, Ananias Escalante and an international team explore the genetic diversity of malarial parasite P. vivax in the Americas and other areas of the world. The study shows greater genetic diversity for P. vivax compared with earlier studies and points to plausible routes of malarial introduction into the New World.

Contact: Joseph Caspermeyer
Joseph.Caspermeyer@asu.edu
Arizona State University

Public Release: 3-Jul-2013
Cell
New approaches to understanding infection may uncover novel therapies against influenza
The influenza virus' ability to mutate quickly has produced new, emerging strains that make drug discovery more critical than ever. For the first time, researchers at Seattle BioMed, along with collaborators at the University of California, San Diego School of Medicine, St. Jude Children's Research Hospital and the University of Washington, have mapped how critical molecules regulate both the induction and resolution of inflammation during flu infection. The results are published in the journal Cell.
National Institutes of Health

Contact: Hannah Krakauer
hannah.krakauer@seattlebiomed.org
206-256-7259
Seattle Biomedical Research Institute

Public Release: 3-Jul-2013
Nature
First comprehensive regulatory map is a blueprint for how to defeat tuberculosis
Despite decades of research on the bacterium that causes tuberculosis (TB), scientists have not had a comprehensive understanding of how the bacterium is wired to adapt to changing conditions in the host. Now, researchers have taken the first steps toward a complete representation of the regulatory network for Mycobacterium tuberculosis. This map of the network of genes that control the TB bacterium will yield unique insights into how the bacteria survive in the host.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Hannah Krakauer
hannah.krakauer@seattlebiomed.org
206-256-7259
Seattle Biomedical Research Institute

Public Release: 3-Jul-2013
American Journal of Human Genetics
DNA markers in low-IQ autism suggest heredity
Researchers who compared the DNA of patients with autism and intellectual disability to that of their unaffected siblings found that the affected siblings had significantly more "runs of homozygosity," or blocks of DNA that are the same from both parents. The finding suggests a role for recessive inheritance in this autism subgroup and highlights homozygosity as a new approach to understanding genetic mechanisms in autism.
Simons Foundation, National Institutes of Health, Burroughs Wellcome Fund

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University

Public Release: 1-Jul-2013
Genome Research
ACRG and BGI report new evidence for the genetic bases of liver cancer
The Asian Cancer Research Group, an independent, not-for-profit company in collaboration with BGI, the world's largest genomics organization, and The University of Hong Kong, jointly announced the publication of findings from a study of recurrent mutations in hepatocellular carcinoma, one of the most deadly cancers worldwide, in the international journal Genome Research. The study provides new insights into potential therapeutic intervention strategies for this common form of liver cancer.

Contact: Jia Liu
liujia@genomics.cn
BGI Shenzhen

Public Release: 26-Jun-2013
Cell biologist to begin work on discovering structure of malaria parasite genome
Plasmodium, which causes malaria, requires specific human and mosquito tissues to complete its life cycle. The progression and control of this life cycle could be better understood by studying changes of the 3-D structure of the parasite's genome. The University of California, Riverside and the University of Washington have received a four-year grant exceeding $2 million from the National Institutes of Health to discover this 3-D structure of Plasmodium's genome during the parasite's erythrocytic cycle.
National Institutes of Health

Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside

Public Release: 26-Jun-2013
Nature
The evolution of throwing
The ability to throw an object with great speed and accuracy is a uniquely human adaptation, one that Harvard researchers say played a key role in our evolution. They find that a suite of changes to the upper body that evolved by two million years ago allowed early humans to hunt more effectively by throwing, paving the way for a host of later adaptations, including increases in brain size and migration out of Africa.

Contact: Peter Reuell
preuell@fas.harvard.edu
617-496-8070
Harvard University

Showing releases 376-400 out of 712.

<< < 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 > >>