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Key: Meeting M      Journal J      Funder F

Showing releases 401-425 out of 707.

<< < 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 > >>

Public Release: 17-Oct-2013
Science
Researchers advance toward engineering 'wildly new genome'
In two parallel projects, researchers have rewritten the genetic code of the bacterium E. coli. In the first study they created a genetically and biochemically novel organism by erasing every example of a single codon from the entire genome. In the second, they tested whether all codons could be swapped to a synonymous codon in 42 separate genes, while eliminating every instance of 13 codons throughout each of those genes.
Department of Energy, National Science Foundation, Defense Advanced Research Projects Agency, Arnold and Mabel Beckman Foundation, Department of Defense

Contact: David Cameron
david_cameron@hms.harvard.edu
617-432-0441
Harvard Medical School

Public Release: 16-Oct-2013
New England Journal of Medicine
Pancreatic cancer patient survival 'significantly higher' with nab-paclitaxel, says TGen-led study
By all measures, the addition of nab-paclitaxel for the treatment of patients with advanced pancreatic cancer was superior to the survival for patients who received only gemcitabine, according to the results of a study led by the Translational Genomics Research Institute and Scottsdale Healthcare, published today by The New England Journal of Medicine.
Celgene Corporation

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute

Public Release: 16-Oct-2013
Science Translational Medicine
Study suggests: Blood test can differentiate between benign lung nodules and early stage lung cancer
Indi today announced the results of a major study, which suggests that quantifying a combination of blood proteins can distinguish between benign lung nodules and early-stage lung cancer with high probability. The study, published today in Science Translational Medicine, suggests that when this group of proteins is detected, and their relative concentrations are used to identify a patient's lung nodule as benign, the classifier result is correct more than 90 percent of the time.

Contact: Eliot Dobris
eliot@eliotdobris.com
415-902-1241
Indi (Integrated Diagnostics)

Public Release: 13-Oct-2013
Nature Methods
Database of disease genes shows potential drug therapies
Researchers at Washington University School of Medicine in St. Louis have created a massive online database that matches thousands of genes linked to cancer and other diseases with drugs that target those genes. Some of the drugs are approved by the US Food and Drug Administration, while others are in clinical trials or just entering the drug development pipeline.
NIH/National Human Genome Research Institute

Contact: Caroline Arbanas
arbanasc@wustl.edu
314-286-0109
Washington University School of Medicine

Public Release: 10-Oct-2013
University of Utah awarded $20.4 million from NIH to advance translational research in medicine
The Center's track record of success this month has earned it a $20.4 million grant from the National Institutes of Health that will allow it to provide support for all aspects of translational research over the next five years.
National Institutes of Health

Contact: Melinda Rogers
melinda.rogers@hsc.utah.edu
801-608-9888
University of Utah Health Sciences

Public Release: 10-Oct-2013
Cell
The Cancer Genome Atlas exposes more secrets of lethal brain tumor
Scientists at UT MD Anderson Cancer Center and collaborators paint a more detailed picture of the genomic abnormalities that drive glioblastoma multiforme. Rich data set will underpin research and treatment advances.
National Institutes of Health/The Cancer Genome Atlas

Contact: Scott Merville
smerville@mdanderson.org
713-792-0661
University of Texas M. D. Anderson Cancer Center

Public Release: 10-Oct-2013
PLOS Computational Biology
New theory of synapse formation in the brain
The human brain keeps changing throughout a person's lifetime. Jülich neuroinformatician Dr. Markus Butz has now been able to ascribe the formation of new neural networks in the visual cortex to a simple homeostatic rule. With this explanation, he and his colleague Dr. Arjen van Ooyen from Amsterdam also provide a new theory on the plasticity of the brain -- and a novel approach to understanding learning processes and treating brain injuries and diseases.

Contact: Tobias Schlößer
t.schloesser@fz-juelich.de
49-246-161-4771
Forschungszentrum Juelich

Public Release: 9-Oct-2013
PLOS ONE
McGill discovery should save wheat farmers millions of dollars
Research by a McGill team suggest that the solution to pre-harvest wheat sprouting may lie not with genetics alone, but rather with a combination of genetic and epigenetic factors.
Natural Sciences and Engineering Research Council of Canada

Contact: Katherine Gombay
katherine.gombay@mcgill.ca
514-398-2189
McGill University

Public Release: 7-Oct-2013
2 Gladstone scientists inducted into the California Academy of Sciences
In an unprecedented move, the California Academy of Sciences today will induct two scientists from the Gladstone Institutes, President R. Sanders "Sandy" Williams, M.D., and Investigator Katherine Pollard, Ph.D., as Academy Fellows, bestowing yet another honor on two of San Francisco's most esteemed scientists.

Contact: Anne Holden
anne.holden@gladstone.ucsf.edu
415-734-2534
Gladstone Institutes

Public Release: 7-Oct-2013
PLOS Genetics
Unexpected genomic change through 400 years of French-Canadian history
Researchers at the Sainte-Justine University Hospital Center and University of Montreal have discovered that the genomic signature inherited by today's 6 million French-Canadians from the first 8,500 French settlers who colonized New France some 400 years ago has gone through an unparalleled change in human history, in a remarkably short timescale.
Génome Québec, Fondation canadienne pour l'innovation, Institut de recherche en santé du Canada

Contact: William Raillant-Clark
w.raillant-clark@umontreal.ca
514-343-7593
University of Montreal

Public Release: 7-Oct-2013
American Journal of Botany
Microsatellites are repetitive, but the lab work doesn't have to be
Researchers at the University of Cincinnati have established a method that increases the ease and affordability of microsatellite marker development -- streamlining the process by reducing the number of steps involved. The new protocol is described in the Oct. issue of Applications in Plant Sciences. In the new protocol, multiple microsatellites can be fluorescently labeled and amplified in the same PCR reaction, significantly reducing the total number of PCR reactions required for each study.

Contact: Beth Parada
apps@botany.org
American Journal of Botany

Public Release: 6-Oct-2013
Nature Genetics
Massive DNA study points to new heart drug targets and a key role for triglycerides
A global hunt for genes that influence heart disease risk has uncovered 157 changes in human DNA that alter the levels of cholesterol and other blood fats -- a discovery that could lead to new medications. Each of the changes points to genes that can modify levels of cholesterol and other blood fats and are potential drug targets. Many of the changes point to genes not previously linked to blood fats, also called lipids.
National Institutes of Health, National Science Foundation

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 3-Oct-2013
NSF grant funds study to unlock secrets of biodiversity
The tropics are home to a far greater diversity of life than any other region on the planet, but the reasons for this disparity have puzzled scientists for centuries. To help shed light on the ultimate causes of biodiversity, the National Science Foundation has awarded $2 million over five years through the Dimensions in Biodiversity program to a group of researchers from five institutions, including the University of Chicago. The collaboration will investigate the biological mechanisms that drive biodiversity in butterflies.
National Science Foundation

Contact: Kevin Jiang
kevin.jiang@uchospitals.edu
773-795-5227
University of Chicago Medical Center

Public Release: 3-Oct-2013
Molecular Cell
Scientists discover new role for cell dark matter in genome integrity
University of Montreal researchers have discovered how telomerase, a molecule essential for cancer development, is directed to structures on our genome called telomeres in order to maintain its integrity and in turn, the integrity of the genome.
Canadian Institutes of Health Research

Contact: William Raillant-Clark
w.raillant-clark@umontreal.ca
514-343-7593
University of Montreal

Public Release: 3-Oct-2013
Science
New technique identifies novel class of cancer's drivers
Scientists have revealed nearly 100 genetic variants implicated in the development of cancers such as breast cancer and prostate cancer. The new method designed by the team, described in the journal Science, identified these variants in the under-explored regions of DNA that do not code for proteins, but instead influence activity of other genes. As even more whole genome sequences become available, this approach can be applied to find any potential disease-causing variant in the non-coding regions of the genome.

Contact: Aileen Sheehy
press.office@sanger.ac.uk
44-012-234-92368
Wellcome Trust Sanger Institute

Public Release: 2-Oct-2013
IRICoR and Université de Montréal license a novel program for early-onset morbid obesity to Pfizer
The Institute for Research in Immunology and Cancer -- Commercialization of Research and its host institution, the Université de Montréal today announced the licensing to Pfizer Inc. of a novel early-onset morbid obesity pre-clinical program developed at the Institute for Research in Immunology and Cancer.

Contact: William Raillant-Clark
w.raillant-clark@umontreal.ca
514-343-7593
University of Montreal

Public Release: 1-Oct-2013
64th Annual Meeting of the American Association for the Study of Liver Diseases
TGen-led study identifies genes associated with unhealthy liver function
A groundbreaking study of nearly 2,300 extremely obese diabetes patients, led by the Translational Genomics Research Institute, has identified genes associated with unhealthy liver function. This is believed to be the nation's first large-scale genome-wide association study in overweight patients with diabetes.

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute

Public Release: 1-Oct-2013
Nature Methods
Search tool for gene expression databases could uncover therapeutic targets, biological processes
A new computational tool developed by US and Israeli scientists will help scientists exploit the massive databases of gene expression experimental results that have been created over the past decade. Researchers say it could uncover new links between diseases and treatments and provide new insights into biological processes.
National Institutes of Health, National Science Foundation

Contact: Byron Spice
bspice@cs.cmu.edu
412-268-9068
Carnegie Mellon University

Public Release: 1-Oct-2013
PhytoKeys
The MGC Herbarium: Information source of plant diversity in the Mediterranean
The MGC Herbarium of the University of Malaga (Spain), which contains the impressive 76.000 sheets of vascular plants, is one of the most important resources for understanding the biodiversity in the South of Spain. The basic information about the MGC Herbarium has been published in a recent data paper available through the open access journal PhytoKeys.

Contact: José García-Sánchez
jgarcias@uma.es
Pensoft Publishers

Public Release: 1-Oct-2013
PeerJ
Scientists who share data publicly receive more citations
A new study finds that papers with data shared in public gene expression archives received increased numbers of citations for at least five years. The large size of the study allowed the researchers to exclude confounding factors that have plagued prior studies of the effect and to spot a trend of increasing dataset reuse over time. The findings will be important in persuading scientists that they can benefit directly from publicly sharing their data.

Contact: Heather Piwowar
hpiwowar@gmail.com
PeerJ

Public Release: 27-Sep-2013
MOgene awarded $1.5 million from US Department of Energy
The MGC project is one of 15 energy projects selected by the ARPA-E to participate in the agency's new REMOTE program -- Reducing Emissions using Methanotrophic Organisms for Transportation Energy.

Contact: Melanie Bernds
mbernds@danforthcenter.org
314-587-1647
Donald Danforth Plant Science Center

Public Release: 27-Sep-2013
Magnetic Resonance in Medicine
New breast cancer imaging technique could cut down on false positives
A joint BYU-Utah research team is developing a new breast cancer screening technique that has the potential to reduce false positives, and, possibly, minimize the need for invasive biopsies. The group has created an MRI device that could improve both the process and accuracy of breast cancer screening by scanning for sodium levels in the breast.
National Institutes of Health

Contact: Todd Hollingshead
toddh@byu.edu
801-422-8373
Brigham Young University

Public Release: 26-Sep-2013
Cell
A genetic map for complex diseases
University of Chicago scientists have created one of the most expansive analyses to date of the genetic factors at play in complex diseases such as autism and heart disease by using diseases with known genetic causes to guide them. Identifying trends of co-occurrence among hundreds of diseases in 120 million patients, they created a unique genetic map that has the potential to help diagnose, identify risk factors for and someday develop therapies against complex diseases.
National Institutes of Health

Contact: Kevin Jiang
kevin.jiang@uchospitals.edu
773-795-5227
University of Chicago Medical Center

Public Release: 25-Sep-2013
New NIH-funded resource focuses on use of genomic variants in medical care
Three new grants from the National Institutes of Health totaling more than $25 million over four years will help three research groups to develop authoritative information on the millions of genomic variants relevant to human disease and the hundreds that are expected to be useful for clinical practice.
National Institutes of Health

Contact: Steven Benowitz
steven.benowitz@nih.gov
301-451-8325
NIH/National Human Genome Research Institute

Public Release: 25-Sep-2013
Infection and Immunity
Researchers develop model to study human response to infections that cause peptic ulcers
Virginia Tech esearchers have developed a model that helps scientists and clinicians understand that complex interactions of a type of bacteria that is the leading cause of peptic ulcers. The discovery may inform changes in the ways doctors treat patients. An estimated 4 million Americans have peptic ulcers.
National Institutes of Health

Contact: Tiffany Trent
ttrent@vt.edu
540-231-6822
Virginia Tech

Showing releases 401-425 out of 707.

<< < 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 > >>