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Key: Meeting M      Journal J      Funder F

Showing releases 426-450 out of 743.

<< < 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 > >>

Public Release: 2-Dec-2013
The importance of standardizing drug screening studies
A bioinformatics expert at the IRCM, Benjamin Haibe-Kains, recently published an article stressing the importance of standardizing drug screening studies in the prestigious scientific journal Nature. The study supports the need for further development and standardization to improve the reproducibility of drug screening studies, as they are important in identifying new therapeutic agents and their potential combinations with existing drugs.

Contact: Julie Langelier
Institut de recherches cliniques de Montreal

Public Release: 28-Nov-2013
Nucleic Acids Research
CNIO scientists create the first large catalog of interactions between drugs and proteins
A Spanish National Cancer Research Centre work, led by Alfonso Valencia, Vice-Director of Basic Research, and Michael L. Tress, brings together the biggest collection of interactions between pharmacological molecules, including other compounds, and proteins. The catalog includes 16,600 compounds, of which 1,300 contain pharmacological descriptions, and 500,000 interactions that witness the extensive social network that governs the functioning of organisms. The information is available to the entire scientific community via the public FireDB database.

Contact: Nuria Noriega
Centro Nacional de Investigaciones Oncologicas (CNIO)

Public Release: 26-Nov-2013
Scientists characterize effects of transplanted fecal microbiota
Scientists at the Institute for Genome Sciences at the University of Maryland School of Medicine and physicians at Sinai Hospital, Baltimore, Md., have found that restoring the normal, helpful bacteria of the gut and intestines may treat patients suffering from recurrent Clostridium difficile infections. Transplanting fecal matter of healthy donors into patients with recurrent C. difficile infection appears to restore normal bacterial composition and resolve infection. The study findings appear in the Nov. 26 issue of PLOS ONE.
Weinberg Foundation, Friedman and Friedman Group, and others

Contact: Sarah Pick
University of Maryland Medical Center

Public Release: 25-Nov-2013
Nature Biotechnology
University of Massachusetts Medical School scientists re-imagine how genomes are assembled
Scientists at the University of Massachusetts Medical School have developed a new method for piecing together the short DNA reads produced by next-generation sequencing technologies that are the basis for building complete genome sequences.

Contact: Jim Fessenden
University of Massachusetts Medical School

Public Release: 25-Nov-2013
Chromosomes show off their shapes
Weizmann Institute researchers calculate the shape of a chromosome.

Contact: Yivsam Azgad
Weizmann Institute of Science

Public Release: 25-Nov-2013
Journal of Clinical Investigation
Identification of a genetic mutation associated with steroid-resistant nephritic syndrome
In this issue of the Journal of Clinical Investigation, Friedhelm Hildebrandt and colleagues at Boston Children's Hospital identified mutations in gene encoding the aarF domain containing kinase 4 (ADCK4) in 15 individuals with steroid-resistant nephritic syndrome from eight different families.
National Institutes of Health, Kidney Foundation of Canada and Nephcure Canada, National Research Foundation

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 25-Nov-2013
Journal of Clinical Investigation
Identifying targets of autoantibodies
In this issue of the Journal of Clinical Investigation, Jordan Price and colleagues at Stanford University developed a microarray to identify cytokines, chemokines, and other circulating proteins as potential targets of the autoantibodies produced by SLE patients.
National Science Foundation, National Institutes of Health, Canadian Institutes of Health, National Organization for Rare Disorders

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 21-Nov-2013
Stanford scientists think mysterious virus could be a signal of a weak immune system
Genomic analysis of transplant patients finds an opportunistic microorganism whose elevated presence could be used an indicator in treatment. This paper offers a comprehensive look at the virome as well as suggestions of how the discovered indicator could be used in therapies involving the immune system.
Howard Hughes Medical Institute

Contact: Tom Abate
Stanford School of Engineering

Public Release: 20-Nov-2013
Geneticists receive funding to improve citrus production and health
Two plant geneticists at the University of California, Riverside have received a $450,000 grant from the National Institute of Food and Agriculture of the US Department of Agriculture to develop a "high-density SNP genotyping array," a genetic tool that citrus breeders can use to improve the efficiency with which citrus varieties are bred. UC Riverside has a long tradition in citrus research, with citrus production and development of new varieties being a major focus.
National Institute of Food and Agriculture, US Department of Agriculture

Contact: Iqbal Pittalwala
University of California - Riverside

Public Release: 19-Nov-2013
HIV virus spread and evolution studied through computer modeling
Researchers at Los Alamos National Laboratory are investigating the complex relationships between the spread of the HIV virus in a population (epidemiology) and the actual, rapid evolution of the virus (phylogenetics) within each patient's body.
National Institutes of Health

Contact: Nancy Ambrosiano
DOE/Los Alamos National Laboratory

Public Release: 19-Nov-2013
UT Dallas computer scientists create 3-D technique
UT Dallas computer scientists are using a famous mathematician's theory to make 3-D images that are more accurate approximations of the shapes of the original objects.

Contact: LaKisha Ladson
University of Texas at Dallas

Public Release: 19-Nov-2013
Biology Open
A CNIO study recreates the history of life through the genome
One of the most important processes in the life of cells is genome replication. In most organisms genome replication follows a set plan, in which certain regions of the genome replicate before others; alterations in the late replication phases had previously been related to cancer and aging. Now, a team from the Spanish National Cancer Research Centre has for the first time related this process to evolution of life.

Contact: Nuria Noriega
Centro Nacional de Investigaciones Oncologicas (CNIO)

Public Release: 19-Nov-2013
Study to identify functions of hypothetical genes in 2 infectious disease pathogens
The National Institute of Allergy and Infectious Diseases has awarded the University of Chicago $4.4 million over five years to study genes of unknown function in bacteria that cause plague and brucellosis.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Kevin Jiang
University of Chicago Medical Center

Public Release: 17-Nov-2013
Nature Methods
Protein coding 'junk genes' may be linked to cancer
By using a new analysis method, researchers at Karolinska Institutet and Science for Life Laboratory in Sweden have found close to one hundred novel human gene regions that code for proteins. A number of these regions are so-called pseudogenes, which may be linked to cancer.
Swedish Research Council, Swedish Cancer Society, EU FP7 project GlycoHit, and others

Contact: The Press Office
Karolinska Institutet

Public Release: 14-Nov-2013
Journal of Experimental Medicine
A*STAR scientists bring to light mechanism of drug for infections
Scientists at A*STAR's Singapore Immunology Network have discovered the exact mode of action by plerixafor, a drug commonly prescribed to stimulate immune responses in patients suffering from neutropenia, which causes them to become prone to oral, skin, genital infections and in worst cases, a fatal whole-body infection . A better understanding of the drug's mechanism can improve its usage to more effectively reduce risk of infections in these patients.

Contact: Tan Yun Yun
Agency for Science, Technology and Research (A*STAR), Singapore

Public Release: 13-Nov-2013
Molecular Cell
Deletion of any single gene provokes mutations elsewhere in the genome
Johns Hopkins researchers report that the deletion of any single gene in yeast cells puts pressure on the organism's genome to compensate, leading to a mutation in another gene. Their discovery, which is likely applicable to human genetics because of the way DNA is conserved across species, could have significant consequences for the way genetic analysis is done in cancer and other areas of research, they say.
NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute of General Medical Sciences

Contact: Catherine Kolf
Johns Hopkins Medicine

Public Release: 13-Nov-2013
Gut microbes in healthy kids carry antibiotic resistance genes
Friendly microbes in the intestinal tracts of healthy American children have numerous antibiotic resistance genes, according to results of a pilot study by scientists at Washington University School of Medicine in St. Louis. The genes are cause for concern because they can be shared with harmful microbes, interfering with the effectiveness of antibiotics in ways that can contribute to serious illness and, in some cases, death.

Contact: Michael C. Purdy
Washington University School of Medicine

Public Release: 13-Nov-2013
Wireless sensors used to study meditation's effect on heart health
Demystifying meditation with science, researchers at the Scripps Translational Science Institute have teamed with The Chopra Foundation and The Chopra Center for Wellbeing in a novel study of the ancient practice that uses wireless health sensors to collect physiological data from meditators. The research might for the first time demonstrate the immediate influence of meditation on blood pressure and markers of stress, and eventually guide better and more individualized treatments.
Chopra Foundation

Contact: Keith Darce
Scripps Health

Public Release: 10-Nov-2013
Philosophical Transactions of the Royal Society B
Fast-mutating DNA sequences shape early development; guided evolution of uniquely human traits
What does it mean to be human? According to scientists the key lies, ultimately, in the billions of lines of genetic code that comprise the human genome. The problem, however, has been deciphering that code. But now, researchers at the Gladstone Institutes have discovered how the activation of specific stretches of DNA control the development of uniquely human characteristics -- and tell an intriguing story about the evolution of our species.
NIH/National Institute of General Medical Sciences, NIH/National Heart, Lung and Blood Institute

Contact: Anne Holden
Gladstone Institutes

Public Release: 10-Nov-2013
Nature Biotechnology
Single-cell genome sequencing gets better
Researchers led by bioengineers at the University of California, San Diego have generated the most complete genome sequences from single E. coli cells and individual neurons from the human brain. Preliminary data suggest that individual neurons from the same brain have different genetic compositions. The breakthrough, published in Nature Biotechnology, comes from a new single-cell genome sequencing technique that confines genome amplification to fluid-filled wells with a volume of just 12 nanoliters.
National Institutes of Health, US National Science Foundation

Contact: Daniel Kane
University of California - San Diego

Public Release: 8-Nov-2013
Journal of Biological Chemistry
TGen-led study reveals TWEAK-Fn14 as key drug target
A cellular pathway interaction known as TWEAK-Fn14, often associated with repair of acute injuries, also is a viable target for drug therapy that could prevent the spread of cancer, especially brain cancer, according to a study led by the Translational Genomics Research Institute.
Ben and Catherine Ivy Foundation, NIH/National Cancer Institute

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 7-Nov-2013
PLOS Genetics
Dartmouth researcher finds novel genetic patterns that make us rethink biology and individuality
Scott Williams, Ph.D., of the iQBS at Dartmouth, has made two novel discoveries: 1) a person can have several DNA mutations in parts of their body, with their original DNA in the rest -- resulting in several different genotypes in one individual -- and 2) some of the same genetic mutations occur in unrelated people. We think of each person's DNA as unique, but if a person can have more than one genotype, this may have broad implications.
National Institutes of Health

Contact: Derik Hertel
The Geisel School of Medicine at Dartmouth

Public Release: 7-Nov-2013
Nature Biotechnology
Cost-effective method accurately orders DNA sequencing along entire chromosomes
A new computational method has been shown to quickly assign, order and orient DNA sequencing information along entire chromosomes. The method may help overcome a major obstacle that has delayed progress in designing rapid, low-cost -- but still accurate -- ways to assemble genomes from scratch. Data gleaned through this new method can also validate certain types of chromosomal abnormalities in cancer.
National Institutes of Health, NIH/National Human Genome Research Institute, National Science Foundation

Contact: Leila Gray
University of Washington

Public Release: 7-Nov-2013
UNH, UC Davis launch network to study environmental microbes
A grant to the University of New Hampshire and the University of California, Davis, will help biologists identify an abundant yet largely unknown category of organisms, leading to better understanding of the vital environmental functions they play. The National Science Foundation awarded the universities $500,000 to develop a Research Coordination Network on eukaryotic biodiversity. The work will apply new genome sequencing technology to study and classify microscopic eukaryote species like nematodes, fungi, and single-celled animals.
National Science Foundation

Contact: Beth Potier
University of New Hampshire

Public Release: 7-Nov-2013
Allen Institute for Brain Science partners with imec for development of next-generation tools
The Allen Institute in partnership with imec, the Howard Hughes Medical Institute, the Gatsby Charitable Foundation, the Wellcome Trust and University College London, have committed $5.5 million in R&D for the revolutionary neuroscience research tools including the proposed sensor array.

Contact: Steven Cooper
Edelman Public Relations

Showing releases 426-450 out of 743.

<< < 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 > >>